Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
MousePhenoglomerulosclerosis

GLIS2 LBR GRM1 LEPR

1.28e-0568304MP:0005264
MousePhenoincreased urine protein level

IKZF3 SCAMP5 GLIS2 GRM1 LEPR

1.48e-05149305MP:0002962
MousePhenocortical renal glomerulopathies

IKZF3 GLIS2 LBR GRM1 LEPR

1.85e-05156305MP:0000523
MousePhenoincreased B cell number

TET2 IKZF3 NFATC2 SH3BP2 FES DGKZ

2.02e-05271306MP:0005014
MousePhenoabnormal urine protein level

IKZF3 SCAMP5 GLIS2 GRM1 LEPR

2.79e-05170305MP:0006315
MousePhenoincreased pre-B cell number

IKZF3 SH3BP2 FES

3.14e-0529303MP:0003132
MousePhenoabnormal pre-B cell morphology

TET2 IKZF3 SH3BP2 FES

4.99e-0596304MP:0002403
MousePhenoconstricted vagina orifice

LBR LEPR

6.64e-056302MP:0001143
MousePhenotremors

LKAAEAR1 EGR2 WDR81 GRM1 RREB1 LEPR

8.83e-05353306MP:0000745
MousePhenoincreased monocyte cell number

TET2 SH3BP2 FES LBR LEPR

8.94e-05217305MP:0000220
MousePhenoincreased hemoglobin content

TET2 EPOR FES LEPR

9.43e-05113304MP:0005564
MousePhenoabnormal B cell number

TET2 IKZF3 NFATC2 SH3BP2 FES DGKZ LBR

9.82e-05526307MP:0002458
MousePhenoincreased hematocrit

C19orf81 EPOR FES LEPR

1.31e-04123304MP:0002608
MousePhenoincreased lymphocyte cell number

TET2 IKZF3 NFATC2 SH3BP2 FES DGKZ FNDC3A LEPR

2.05e-04797308MP:0005013
MousePhenoabnormal B cell morphology

TET2 IKZF3 NFATC2 SH3BP2 FES DGKZ LBR

2.16e-04597307MP:0004939
MousePhenoabnormal renal glomerulus morphology

IKZF3 GLIS2 LBR GRM1 LEPR

2.24e-04264305MP:0005325
MousePhenoabnormal nephron morphology

TET2 IKZF3 GLIS2 LBR GRM1 LEPR

2.47e-04426306MP:0003881
MousePhenoshort tibia

EGR2 SH3BP2 FNDC3A LBR LEPR

2.66e-04274305MP:0002764
MousePhenoalbuminuria

GLIS2 GRM1 LEPR

3.25e-0463303MP:0002871
MousePhenoabnormal renal corpuscle morphology

IKZF3 GLIS2 LBR GRM1 LEPR

3.62e-04293305MP:0002827
MousePhenoabnormal monocyte cell number

TET2 SH3BP2 FES LBR LEPR

3.74e-04295305MP:0012441
MousePhenoabnormal monocyte morphology

TET2 SH3BP2 FES LBR LEPR

4.10e-04301305MP:0002620
MousePhenoabnormal lymphocyte cell number

TET2 IKZF3 NFATC2 SH3BP2 FES DGKZ FNDC3A LBR SERF1A LEPR

4.26e-0413903010MP:0000717
MousePhenoabnormal kidney cortex morphology

IKZF3 GLIS2 LBR GRM1 LEPR

5.74e-04324305MP:0000521
MousePhenoincreased susceptibility to endotoxin shock

FES TREML1 LEPR

5.86e-0477303MP:0008735
MousePhenoabnormal pro-B cell morphology

TET2 SH3BP2 FES

6.09e-0478303MP:0005432
MousePhenorenal fibrosis

GLIS2 LBR LEPR

6.09e-0478303MP:0003985
MousePhenodecreased exploration in new environment

FNDC3A LBR GRM1 ZDHHC8 LEPR SLC44A3

6.44e-04510306MP:0001417
MousePhenoabnormal lymphocyte morphology

TET2 IKZF3 NFATC2 SH3BP2 FES DGKZ FNDC3A LBR SERF1A LEPR

7.16e-0414833010MP:0002619
MousePhenoincreased IgE level

IKZF3 NFATC2 LEPR

7.30e-0483303MP:0002497
MousePhenodecreased lymphocyte cell number

TET2 IKZF3 SH3BP2 FES DGKZ LBR SERF1A LEPR

8.96e-04992308MP:0005016
MousePhenoincreased neutrophil cell number

TET2 IKZF3 FES LBR LEPR

1.02e-03368305MP:0000219
MousePhenoincreased glomerular capsule space

GLIS2 LEPR

1.10e-0323302MP:0011501
MousePhenoabnormal tibia morphology

EGR2 SH3BP2 FNDC3A LBR LEPR

1.11e-03375305MP:0000558
MousePhenodecreased myeloid cell number

TET2 EPOR IKZF3 RREB1 TREML1 LEPR

1.12e-03567306MP:0013662
MousePhenoabnormal cell proliferation

IKZF3 EGR2 SH3BP2 GCM1 DGKZ LBR GRM1 RREB1 LEPR

1.15e-031294309MP:0000350
MousePhenoabnormal hindlimb zeugopod morphology

EGR2 SH3BP2 FNDC3A LBR LEPR

1.19e-03381305MP:0003857
MousePhenopremature death

TET2 IKZF3 SCAMP5 SH3BP2 GLIS2 LBR GRM1 LEPR

1.31e-031051308MP:0002083
MousePhenoabnormal myeloid cell number

TET2 EPOR IKZF3 FES RREB1 TREML1 LEPR

1.31e-03806307MP:0013661
MousePhenodecreased B cell number

TET2 IKZF3 SH3BP2 FES LBR

1.38e-03394305MP:0005017
MousePhenoincreased cell proliferation

IKZF3 EGR2 GCM1 DGKZ RREB1

1.41e-03396305MP:0000351
MousePhenoincreased granulocyte number

TET2 IKZF3 FES SLC7A5 LBR LEPR

1.46e-03597306MP:0000322
MousePhenoabnormal liver physiology

TET2 EPOR SH3BP2 FES LEPR

1.49e-03401305MP:0000609
MousePhenodecreased leukocyte cell number

TET2 IKZF3 SH3BP2 FES DGKZ LBR SERF1A LEPR PHACTR1

1.50e-031342309MP:0000221
MousePhenoabnormal glomerular capsule space morphology

GLIS2 LEPR

1.51e-0327302MP:0011499
MousePhenoabnormal renal glomerular capsule morphology

GLIS2 GRM1 LEPR

1.52e-03107303MP:0002828
MousePhenoincreased inflammatory response

TET2 IKZF3 SH3BP2 GLIS2 FES DGKZ TREML1 LEPR

1.53e-031077308MP:0001846
MousePhenoabnormal eye physiology

EPOR SH3BP2 FES LBR GRM1 LEPR

1.58e-03606306MP:0005253
MousePhenoabnormal hemoglobin content

TET2 EPOR FES RREB1 LEPR

1.61e-03408305MP:0005563
MousePhenodecreased length of long bones

EGR2 SH3BP2 FNDC3A LBR LEPR

1.63e-03409305MP:0004686
DomainNPIP

NPIPB8 NPIPB13 NPIPB9 NPIPB6 NPIPA5 NPIPA1 NPIPB3 NPIPA3 NPIPB5 NPIPA7 NPIPA2 NPIPB2

6.45e-30145312IPR009443
Pubmed

Novel retinal and cone photoreceptor transcripts revealed by human macular expression profiling.

NPIPA5 NPIPA1 NPIPA3 NPIPA2

8.56e-12461418055785
Pubmed

The sequence and analysis of duplication-rich human chromosome 16.

NPIPB8 NPIPB9 NPIPB11 NPIPB3 NPIPB2

5.50e-079061515616553
Pubmed

Positive selection of a gene family during the emergence of humans and African apes.

NPIPA1 NPIPA8

3.03e-06261211586358
Pubmed

Diacylglycerol kinase zeta in hypothalamus interacts with long form leptin receptor. Relation to dietary fat and body weight regulation.

DGKZ LEPR

3.03e-06261211078732
Pubmed

Tyrosine phosphorylation of 3BP2 regulates B cell receptor-mediated activation of NFAT.

NFATC2 SH3BP2

3.03e-06261219833725
Pubmed

Receptor-mediated dimerization of JAK2 FERM domains is required for JAK2 activation.

EPOR LEPR

9.07e-06361230044226
Pubmed

Erythropoietin protects against diabetes through direct effects on pancreatic beta cells.

EPOR LEPR

9.07e-06361221149549
Pubmed

Calcineurin Undergoes a Conformational Switch Evoked via Peptidyl-Prolyl Isomerization.

NFATC2 RCAN3

9.07e-06361226248042
Pubmed

Model for growth hormone receptor activation based on subunit rotation within a receptor dimer.

EPOR LEPR

9.07e-06361216116438
Pubmed

Divergent origins and concerted expansion of two segmental duplications on chromosome 16.

NPIPB3 NPIPB5

9.07e-06361211948212
Pubmed

The Majority of CD45- Ter119- CD31- Bone Marrow Cell Fraction Is of Hematopoietic Origin and Contains Erythroid and Lymphoid Progenitors.

EPOR LEPR

1.81e-05461230314756
Pubmed

NFATc1 in mice represses osteoprotegerin during osteoclastogenesis and dissociates systemic osteopenia from inflammation in cherubism.

NFATC2 SH3BP2

1.81e-05461218846253
Pubmed

Regulation of Vascular Smooth Muscle Cell Dysfunction Under Diabetic Conditions by miR-504.

EGR2 LEPR

1.81e-05461226941017
Pubmed

Early growth response proteins (EGR) and nuclear factors of activated T cells (NFAT) form heterodimers and regulate proinflammatory cytokine gene expression.

NFATC2 EGR2

3.02e-05561212560487
Pubmed

CD44 variant inhibits insulin secretion in pancreatic β cells by attenuating LAT1-mediated amino acid uptake.

SLC7A5 LEPR

4.52e-05661229434323
Pubmed

Up-regulated expression of a novel gene in activated human peripheral blood mononuclear cells that is a truncated paralog of the human system L-amino acid transporter 1.

SLC7A5P2 SLC7A5

6.32e-05761212009310
Pubmed

Identification of novel roles of the cytochrome p450 system in early embryogenesis: effects on vasculogenesis and retinoic Acid homeostasis.

EPOR EGR2

2.33e-041361212917333
Pubmed

A high-throughput candidate gene mutation screen in lymphoproliferative and myeloproliferative neoplasias.

EPOR FES

3.57e-041661219464057
Pubmed

Activin promotes differentiation of cultured mouse trophoblast stem cells towards a labyrinth cell fate.

KDM5C GCM1

4.05e-041761219716815
Pubmed

Phactr4 regulates neural tube and optic fissure closure by controlling PP1-, Rb-, and E2F1-regulated cell-cycle progression.

EGR2 PHACTR1

5.08e-041961217609112
Pubmed

The histone demethylase Jarid1b ensures faithful mouse development by protecting developmental genes from aberrant H3K4me3.

EGR2 KDM5C

5.63e-042061223637629
Pubmed

Genome duplications and other features in 12 Mb of DNA sequence from human chromosome 16p and 16q.

NPIPB7 NPIPB4 NPIPA1

5.77e-049261310493829
Pubmed

Jak2 is essential for signaling through a variety of cytokine receptors.

EPOR FES

6.22e-04216129590173
Pubmed

Biological pathway-based genome-wide association analysis identified the vasoactive intestinal peptide (VIP) pathway important for obesity.

NFATC2 EGR2

7.48e-042361220379146
Pubmed

Failure of extra-embryonic progenitor maintenance in the absence of dosage compensation.

KDM5C GCM1

7.48e-042361222573614
Pubmed

A Grhl2-dependent gene network controls trophoblast branching morphogenesis.

TNK1 GCM1

1.03e-032761225758223
Pubmed

Synaptic GAP and GEF Complexes Cluster Proteins Essential for GTP Signaling.

DGKZ GRM1 NCDN PHACTR1

1.52e-0328161428706196
CytobandEnsembl 112 genes in cytogenetic band chr16p12

NPIPB7 NPIPB4 NPIPB6 SLC7A5P2 NPIPB3 NPIPB5 NPIPA8

3.37e-09172617chr16p12
Cytoband16p13.11

NPIPA5 NPIPA1 NPIPA3 NPIPA2

2.45e-082361416p13.11
Cytoband16p12.2

NPIPB4 SLC7A5P2 NPIPB3 NPIPB5

1.80e-073761416p12.2
Cytoband16p11.2

NPIPB8 NPIPB7 NPIPB13 NPIPB12 NPIPB6 NPIPB11

2.20e-0719161616p11.2
CytobandEnsembl 112 genes in cytogenetic band chr16p13

NPIPA5 GLIS2 NPIPA1 NPIPA3 NPIPA7 NPIPA2 NPIPB2

1.60e-06426617chr16p13
CytobandEnsembl 112 genes in cytogenetic band chr16p11

NPIPB8 NPIPB13 NPIPB12 NPIPB9 NPIPB11

3.54e-05278615chr16p11
CytobandEnsembl 112 genes in cytogenetic band chr6p24

RREB1 PHACTR1

3.96e-0370612chr6p24
GeneFamilyPHD finger proteins

TAF3 KDM5C

7.93e-039027288
GeneFamilySH2 domain containing

SH3BP2 FES

9.90e-03101272741
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Immune-Lymphocytic_B|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

IKZF3 NYAP2 SLC7A5 FNDC3A PKD1L1-AS1

3.34e-061676150130743084dbcb20e10f96715d30961122150cbf
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Immune-Lymphocytic_B-Plasma_Cell-|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

IKZF3 NYAP2 SLC7A5 FNDC3A PKD1L1-AS1

3.34e-061676157bcae3797d3a0811e7f39885afdfd29ec517f11b
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Immune-Lymphocytic_B-Plasma_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

IKZF3 NYAP2 SLC7A5 FNDC3A PKD1L1-AS1

3.34e-06167615c6f0209a1ad797631fdfa3efab6db6b1d3e8e315
ToppCellICU-SEP-Myeloid-pDC|ICU-SEP / Disease, Lineage and Cell Type

C19orf81 NPIPB8 SCAMP5 SLC7A5 PHACTR1

3.75e-0617161572c448a0dc4c569bd6b465f9aa395f38034e7ea6
ToppCell(6)_ILC|World / Spleen cell shreds - cell class (v1) and cell subclass (v1)

C19orf81 ZNF385D FES TREML1 SLC44A3

5.94e-06188615de7cb273899d0e0748c85f45c6b5e7f0642ab057
ToppCell(6)_ILC|World / Spleen cell shreds - cell class (v1) and cell subclass (v1)

C19orf81 ZNF385D FES TREML1 SLC44A3

5.94e-06188615f4734d5b703678670ece204a0519cf015e180a6e
ToppCellcellseq2-Endothelial-Endothelial_Vascular-Endothelial_large_blood_vessel-VEC|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

PIK3C2B EGR2 FBXO31 WDR81 ZDHHC8

6.10e-06189615bccb3481ffed597c845fe860da658505316105b5
ToppCellCD8+_Memory_T_cell-CV-3|CD8+_Memory_T_cell / cell class, Virus stimulation and cluster

PRR5L NFATC2 EGR2 SLC7A5 LBR

7.46e-061976159fe3d53346a95c1bbb0fc6a2f2e974889873424b
ToppCellCV-Moderate-3|CV / Virus stimulation, Condition and Cluster

PRR5L NFATC2 EGR2 SLC7A5 LBR

7.46e-061976157031286e300eaccf73b927939f8de3a9d2d5fc74
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-TAM-BDM-TAM-BDM_MHC-Z|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

STAC2 NYAP2 NPIPB4 LEPR

2.16e-051196148eefcf1ace62ad1c90fa5b62ec159c83ec527bf3
ToppCellCOVID-19_Mild-Neu_4|World / 5 Neutrophil clusters in COVID-19 patients

NPIPA5 NPIPA2 ZDHHC8 NPIPA8

2.54e-051246145ef9eb806fb2c8ee5aae0a75503d244b08ee10d4
ToppCellClub_cells-Cryobiopsy_01|World / lung cells shred on cell class, cell subclass, sample id

GCM1 NPIPA3 FER1L5 NCDN

5.21e-0514961481c813588bb5efb7b31141a75d387210dcb76094
ToppCellfacs-Diaphragm-Limb_Muscle-24m-Myeloid-macrophage|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EPOR SCAMP5 WDR81 DGKZ

5.77e-051536144b999892fb797e9f0d391630094f466463299d57
ToppCellfacs-Diaphragm-Limb_Muscle-24m-Myeloid-nan|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EPOR SCAMP5 WDR81 DGKZ

5.77e-05153614e426db29e4ba83e7930dc88c74fc975b177c9540
ToppCellfacs-Diaphragm-Limb_Muscle-24m-Myeloid|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EPOR SCAMP5 WDR81 DGKZ

5.77e-05153614668eacd76aad6054bd7d57e3af0b122c2443465f
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Immune-Lymphocytic_B-Plasma_Cell-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

IKZF3 NPIPB11 NPIPA3 NCDN

6.54e-051586140c9bb7f8d080a052ca71701544a076c6c2ea67cd
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Immune-Lymphocytic_B-Plasma_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

IKZF3 NPIPB11 NPIPA3 NCDN

6.54e-05158614cebb58878b6945074bc1c7d5848d842da5dcbae1
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Immune-Lymphocytic_B|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

IKZF3 NPIPB11 NPIPA3 NCDN

6.54e-051586142cfa6dd36c8ae534cf1dd49366d4b4433388c1e0
ToppCell15-Airway-Epithelial-Submucosal_gland_basal|Airway / Age, Tissue, Lineage and Cell class

TNK1 STAC2 ARHGEF19 EGR2

8.68e-0517061461f8dd5e27df1b8d01ccfd0d25247b34aa8d182c
ToppCellLPS-IL1RA-Lymphocytic_NKT-T_cells-T-cells|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

IKZF3 NFATC2 SLC7A5 RCAN3

8.88e-05171614539ea88acc6f948efdeae8b69e5c5ffaee29f1d9
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Lymphoid-CD4/CD8-CD4_INF-G|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

IKZF3 NFATC2 RCSD1 RCAN3

8.88e-05171614e6dfbd2652b67577c8834c05348f62150637f348
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Lymphoid-CD4/CD8-CD4_INF|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

IKZF3 NFATC2 RCSD1 RCAN3

8.88e-05171614ddaeb96ce9c9c3bf232b4a42266fa2ee7e8f3f41
ToppCellBronchial_Biopsy-Immune-Mast_cells|Bronchial_Biopsy / Tissue, Lineage and Cell class of Lung Cells from 10X

C19orf81 IKZF3 SLC7A5 NPIPA3

9.08e-05172614c477008444d2d71071177807870d7455e90c2fad
ToppCellLPS-IL1RA-Lymphocytic_NKT-T_cells|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

IKZF3 NFATC2 SLC7A5 RCAN3

9.08e-051726140fc692be845d4225ff8b63bf9195724fc8510c2c
ToppCellLPS-IL1RA+antiTNF-Lymphocytic_NKT-T_cells-T-cells|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

IKZF3 NFATC2 SLC7A5 RCAN3

9.92e-051766149d4a4dfeebb5a8a0f3ab18c37c8ddc2cd2158575
ToppCellLPS-IL1RA+antiTNF-Lymphocytic_NKT-T_cells|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

IKZF3 NFATC2 SLC7A5 RCAN3

9.92e-05176614bb41e9478373726eb460af764de0277b2d09928e
ToppCellLPS-antiTNF-Lymphocytic_NKT-T_cells|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

IKZF3 NFATC2 SLC7A5 RCAN3

9.92e-05176614ea27e18407b8a13e8212830da859efeb8f158690
ToppCellLPS-antiTNF-Lymphocytic_NKT-T_cells-T-cells|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

IKZF3 NFATC2 SLC7A5 RCAN3

9.92e-05176614bfbab3c5b738b3b0b1540f2059d0245fbd8c0031
ToppCell368C-Myeloid-Macrophage-SPP1+_Macrophage_3|Macrophage / Donor, Lineage, Cell class and subclass (all cells)

PRR5L FBXO31 NPIPB11 NCDN

1.01e-04177614eb0cfe8e9a91910f9979608ed47add48d98ce4dd
ToppCellPBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51-Lymphocytic-Lymphocytic_B-Plasma_cell-B_c05-MZB1-XBP1|Mild-Moderate_convalescent_d36-51 / Compartment, severity and other cell annotations on 10x 3' data (130k)

NPIPB12 SCAMP5 NPIPB6 NPIPA2

1.04e-041786146765c6970b1f2b719a20d2afd7471e1c262f3fc4
ToppCellPBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51-Lymphocytic-Lymphocytic_B-Plasma_cell|Mild-Moderate_convalescent_d36-51 / Compartment, severity and other cell annotations on 10x 3' data (130k)

NPIPB12 SCAMP5 NPIPB6 NPIPA2

1.04e-04178614693f1135d9c5545945e80c7ba3d098afc0ccac29
ToppCellSmart-start-Cell-Wel_seq-Neoplastic-Differentiated-like-MES-like-MES-like_hypoxia/MHC-G|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

C19orf81 NPIPA5 NPIPA2 NPIPB2

1.08e-04180614e4add4c94f892a2d93926e5c6dac6a738319d091
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d03-09-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c11-GNLY|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)

PRR5L NPIPB13 NFATC2 DGKZ

1.11e-041816145cecbafc29cc95896e6ccb2c74d9237b9aaece69
ToppCellURO-Myeloid-pDC|URO / Disease, Lineage and Cell Type

C19orf81 SCAMP5 SLC7A5 PHACTR1

1.18e-041846140edb5dd003c2bca0b9e3ec18d03610d68bd52538
ToppCellBac-SEP-Myeloid-pDC|Bac-SEP / Disease, Lineage and Cell Type

C19orf81 SCAMP5 SLC7A5 PHACTR1

1.20e-041856143de50b2042f22b0fb62ff12c76d85cc67649a0bd
ToppCellHealthy_donor-pDC|Healthy_donor / disease group, cell group and cell class (v2)

C19orf81 SCAMP5 SLC7A5 PHACTR1

1.20e-041856147fbb55cbdb39bdecb6063c8ba9776ab06c2666e8
ToppCellControl-Fibroblasts-Adventitial_FB|Control / group, cell type (main and fine annotations)

ZNF385D NFATC2 LEPR PDZRN4

1.28e-04188614706a26c372add839d947749f0521a0e1f5c9b0ec
ToppCellChildren_(3_yrs)-Immune-T_lymphocyte-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

IKZF3 NFATC2 RCSD1 RCAN3

1.31e-04189614df30478b288084a1bd48f660409dcc784040897c
ToppCellInt-URO-Myeloid-pDC|Int-URO / Disease, Lineage and Cell Type

C19orf81 SCAMP5 SLC7A5 PHACTR1

1.31e-0418961437aee7a0acd5fd5dd62f22608d72ff8afe210e5c
ToppCellCD8+_Memory_T_cell-CV-7|CD8+_Memory_T_cell / cell class, Virus stimulation and cluster

IKZF3 SLC7A5 LBR NPIPB5

1.36e-041916149454f642c3621370fa23640b631301346b300950
ToppCell5'-Parenchyma_lung-Immune_Lymphocytic-Lymphocytic_T/NK-CD4-positive,_alpha-beta_T_cell-CD4_T_cells-CD4_T_cells_L.1.1.1.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

IKZF3 NFATC2 SLC7A5 RCSD1

1.36e-0419161429ce21c6e810edd51f13e0fb1083cd44bd57b1d4
ToppCellnucseq-Immune-Lymphocytic_T/NK-Lymphocytic_T/NK-CD4_T|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

IKZF3 NPIPB4 NPIPB3 NPIPB5

1.41e-041936149c9434a3297b85774b4f0ecab6294f44d738e29f
ToppCellChildren_(3_yrs)-Immune-T_lymphocyte|Children_(3_yrs) / Lineage, Cell type, age group and donor

IKZF3 NFATC2 RCSD1 RCAN3

1.41e-04193614b9769b45125d2244afe53f9f71c92c04ddccf980
ToppCellFetal_brain-fetalBrain_Zhong_nature-GW10-Myeloid|GW10 / Sample Type, Dataset, Time_group, and Cell type.

EGR2 RCSD1 PKD1L1-AS1 TREML1

1.44e-041946144f28841c7f37884fc34c6689cd6976c6559d23f1
ToppCellFetal_brain-fetalBrain_Zhong_nature-GW10-Myeloid-Microglia|GW10 / Sample Type, Dataset, Time_group, and Cell type.

EGR2 RCSD1 PKD1L1-AS1 TREML1

1.44e-04194614459e836bcdb6742333684ac23d960efa5e99702f
ToppCellAdult-Immune-T_lymphocyte-D231|Adult / Lineage, Cell type, age group and donor

IKZF3 NFATC2 RCSD1 RCAN3

1.44e-041946145c1dca33f382f37a7deb23e573578343c3b54986
ToppCellImmune-T_lymphocyte|World / Lineage, Cell type, age group and donor

IKZF3 NFATC2 RCSD1 RCAN3

1.44e-04194614f47fa18c87b35a3960557f8169ff7830dd6ecb80
ToppCell3'-Adult-Appendix-Endothelial-blood_vessel_EC-Mature_venous_EC|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ZNF385D NFATC2 EGR2 LEPR

1.47e-041956146a0460d949ccda7c9fe76870d3ee6c2f60677d61
ToppCellnucseq-Endothelial-Endothelial_Vascular-Endothelial_large_blood_vessel|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

ZNF385D PIK3C2B LEPR PDZRN4

1.47e-04195614023e3c97dd3696d74f002ff8da0c04d876c82aef
ToppCellfacs-Lung-ENDOMUCIN-18m-Endothelial-Capillary_Aerocyte_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GLIS2 DGKZ RCSD1 PHACTR1

1.47e-04195614cad21edd90bf3e2fefdf5773a59cb1a664a69ddd
ToppCell3'-Adult-LargeIntestine-Hematopoietic-B_cells-Memory_B|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

IKZF3 EGR2 RCSD1 PHACTR1

1.50e-04196614c7363794fb731848e4343b3a4e4f800f9c81999a
ToppCellParenchymal-10x3prime_v2-Immune_Lymphocytic-T-T_CD4-CD4_TRM/EMRA|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

IKZF3 EGR2 SLC7A5 RCAN3

1.59e-041996145a29db2610ba06a2248325a16cad755d20debf2c
ToppCellParenchymal-NucSeq-Immune_Lymphocytic-T-T_CD8-CD8|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

IKZF3 NFATC2 SLC7A5 RCSD1

1.59e-041996140d6463e368fd611a17327322413fad145f3c7f32
ToppCelldistal-2-Hematologic-CD8+_Naive_T|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

IKZF3 SLC7A5P2 SLC7A5 RCAN3

1.59e-04199614454c6dfa621be02a7fefdba431972f68c67f9383
ToppCellParenchymal-NucSeq-Immune_Lymphocytic-T-T_CD4-CD4|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

IKZF3 NFATC2 SLC7A5 RCSD1

1.59e-04199614fbdde57dd88656621801e65ee2818251588f3874
ToppCellBronchial-NucSeq-Immune_Lymphocytic-T-T_CD8-CD8_CTL|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

IKZF3 PRR5L NFATC2 RCSD1

1.59e-04199614eb188b0b457136b6ee485d3b3052baa30d9c0002
ToppCellParenchymal-NucSeq-Immune_Lymphocytic-T|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

IKZF3 NFATC2 SLC7A5 RCSD1

1.62e-04200614dfdfad881c114e1bc9a64b411e1b00fb37cc859b
ToppCellmedial-Hematologic-CD8+_Naive_T|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

IKZF3 SLC7A5P2 SLC7A5 RCAN3

1.62e-042006142de8fae1011c57270170fb200a8897add7fe9bfc
ToppCellParenchymal-NucSeq-Immune_Lymphocytic-T-T_CD4-CD4_naive/CM|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

IKZF3 NFATC2 RCSD1 RCAN3

1.62e-04200614cded40d5069a6fdbd90ac9a2a0bbef11727b28d5
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW09-Neuronal-Interneuron|GW09 / Sample Type, Dataset, Time_group, and Cell type.

ZNF385D GRM1 NCDN RCAN3

1.62e-04200614a6500d0d2e8bcac92381ab771dbdee66b0e1d48e
ToppCellBronchial-NucSeq-Immune_Lymphocytic-T-T_CD8-CD8|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

IKZF3 NFATC2 SLC7A5 RCSD1

1.62e-0420061420ffb3436d08042f77800513e6ddb3bbc38ae6fe
ToppCelldistal-Hematologic-CD8+_Naive_T-2|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

IKZF3 SLC7A5P2 SLC7A5 RCAN3

1.62e-0420061478c70174911ee465da6b0d1f4aee27043be492cd
ToppCellmedial-2-Hematologic-CD8+_Naive_T|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

IKZF3 SLC7A5P2 SLC7A5 RCAN3

1.62e-042006145e5c1c5b6d2fcfad7b93488b976a68f5be1435e5
ToppCellBronchial-NucSeq-Immune_Lymphocytic-T-T_CD4-CD4|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

IKZF3 NFATC2 SLC7A5 RCSD1

1.62e-042006148474e5d031d25bfb8461d39fa2053da01a6304fc
ToppCellmedial-Hematologic-CD8+_Naive_T-2|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

IKZF3 SLC7A5P2 SLC7A5 RCAN3

1.62e-042006142daa445f983a43ff3ace1198a6793f5c6706bdba
ToppCellCOVID-19-COVID-19_Mild-Lymphocyte-T/NK-NK_activated|COVID-19_Mild / Disease, condition lineage and cell class

IKZF3 PRR5L NFATC2 NPIPA3

1.62e-042006142281debd86e5d92e8fe0397aec9ef670800f7471
ToppCellParenchymal-NucSeq-Immune_Lymphocytic-T-T_CD8|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

IKZF3 NFATC2 SLC7A5 RCSD1

1.62e-0420061466fb892bda1d29e67a65717e85f2ec221f520b2a
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW16-Mesenchymal-BMP_responsible_cell|GW16 / Sample Type, Dataset, Time_group, and Cell type.

NFATC2 EGR2 FES RREB1

1.62e-0420061426251ed8c7fa7e87973d6f59bd398c88ad025395
ToppCellBronchial-NucSeq-Immune_Lymphocytic-T-T_CD4|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

IKZF3 NFATC2 RCSD1 RCAN3

1.62e-042006149de4d6ebb7e9bee5d811519eb05913ef30f70786
ToppCelldistal-2-Endothelial-Vein|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

ZNF385D PIK3C2B LEPR PDZRN4

1.62e-042006142785225956d2422acab90e99b7debe3709cf3308
ToppCellParenchymal-NucSeq-Immune_Lymphocytic-T-T_CD8-CD8_TRM|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

IKZF3 NFATC2 SLC7A5 RCSD1

1.62e-042006149ef322486e46e4ff05a8cbe06cf8019e996c94b3
Diseaselysophosphatidylcholine 20:3 measurement

NFATC2 NPIPA1 NPIPA2

4.33e-0540503EFO_0010362
Diseaseselective IgA deficiency disease

IKZF3 EGR2 DGKZ

6.60e-0546503EFO_1001929
Diseasetriglycerides to total lipids in medium LDL percentage

NYAP2 NPIPA1 NPIPA2

8.48e-0550503EFO_0022334
Diseasetriglycerides to total lipids in large LDL percentage

NYAP2 NPIPA1 NPIPA2

9.00e-0551503EFO_0022331
Diseasetriglycerides to total lipids in small VLDL percentage

NYAP2 NPIPA1 NPIPA2

1.32e-0458503EFO_0022338
Diseasevery low density lipoprotein cholesterol measurement, phospholipids:total lipids ratio

NYAP2 SLC7A5P2 NPIPA1 NPIPA2 LEPR

1.33e-04291505EFO_0008317, EFO_0020946
Diseasephosphatidylcholine 40:7 measurement

NPIPA1 NPIPA2

2.17e-0413502EFO_0021477
Diseasehepatocellular carcinoma (is_implicated_in)

TET2 FES SLC7A5 LEPR

2.53e-04181504DOID:684 (is_implicated_in)
Diseasemultiple sclerosis

TET2 IKZF3 PRR5L SH3BP2 RREB1 PDZRN4

4.86e-04594506MONDO_0005301
Diseaseapolipoprotein A 1 measurement

TET2 NYAP2 FES DGKZ FNDC3A LEPR RCAN3

5.38e-04848507EFO_0004614
Diseasecholesteryl ester measurement, intermediate density lipoprotein measurement

NYAP2 NPIPA1 NPIPA2

5.51e-0494503EFO_0008595, EFO_0010351
Diseasetotal cholesterol measurement, intermediate density lipoprotein measurement

NYAP2 NPIPA1 NPIPA2

6.40e-0499503EFO_0004574, EFO_0008595
Diseasefree cholesterol measurement, intermediate density lipoprotein measurement

NYAP2 NPIPA1 NPIPA2

7.39e-04104503EFO_0008591, EFO_0008595
Diseasebody fat percentage, coronary artery disease

NYAP2 FES

7.58e-0424502EFO_0001645, EFO_0007800
DiseaseAlzheimer disease, educational attainment

TET2 NYAP2 PIK3C2B EGR2

8.16e-04247504EFO_0011015, MONDO_0004975
Diseasediastolic blood pressure, alcohol drinking

SCAMP5 FES FER1L5

1.07e-03118503EFO_0004329, EFO_0006336
DiseaseGlobal developmental delay

SCAMP5 KDM5C PHACTR1

1.50e-03133503C0557874
Diseasealkaline phosphatase measurement

TET2 EGR2 GLIS2 WDR81 RREB1 LEPR PDZRN4

1.53e-031015507EFO_0004533
Diseasemean arterial pressure

NYAP2 NFATC2 FES DGKZ PHACTR1

1.54e-03499505EFO_0006340

Protein segments in the cluster

PeptideGeneStartEntry
PLQPSLDIKPFLPFP

ZNF385D

26

Q9H6B1
LFVPPVAPRPPALKL

SH3BP2

376

P78314
KPTRRKPPCSLPLFP

RCSD1

41

Q6JBY9
KPPCSLPLFPPKVDL

RCSD1

46

Q6JBY9
FLLPPPCKKCLSPPT

PKD1L1-AS1

11

Q9H7B7
NLKTPPECVLTPLPP

NPIPB3

281

Q92617
LKTPPECVLTPLPPS

NPIPB3

301

Q92617
KTPPECLLTPLPPSA

NPIPB3

321

Q92617
LLPPQPVKQFLISPP

RCAN3

136

Q9UKA8
LAKLRPPTPPVPDIC

PDZRN4

346

Q6ZMN7
CPLDTLRVPPPLTPL

EGR2

251

P11161
KDPSLLNFPPPLPAL

LBR

236

Q14739
KTPPECLLTPLPPSA

NPIPA1

306

Q9UND3
NLKTPPECVLTPLPP

NPIPB12

281

F8W0I5
LKTPPECLLTPLPPS

NPIPB12

301

F8W0I5
KTPPECLLTPLPPSA

NPIPB12

321

F8W0I5
KPPSPVCLDLFPVAP

ARHGEF19

41

Q8IW93
PKPLVPAIPICSIPV

NFATC2

376

Q13469
PCIRKFPTPPASQPL

C19orf81

66

C9J6K1
ERYPLPTVLPPLCPK

FAM166C

146

A6NJV1
CQLLPLFLPPTTVPP

NCDN

241

Q9UBB6
PPPRCSLLELPPELL

FBXO31

61

Q5XUX0
LKTPPECLLTPLPPS

NPIPB8

281

E9PQR5
LKECLFVPLPPSPLP

NPIPB8

321

E9PQR5
NLKECLFVPLPPSPL

NPIPB8

341

E9PQR5
LLKPLFPTCPVPEEA

SLC7A5

156

Q01650
LFLPPQLKPARIPDP

LKAAEAR1

156

Q8TD35
PTCVLPDSVVKPLPP

LEPR

526

P48357
NLKTPPECVLTPLPP

NPIPB5

281

A8MRT5
LKTPPECVLTPLPPS

NPIPB5

301

A8MRT5
KTPPECLLTPLPPSA

NPIPB5

321

A8MRT5
LLKPLFPTCPVPEEA

SLC7A5P2

156

Q9GIP4
TPPKDKCLSPDLPLP

GLIS2

151

Q9BZE0
NIKECPLAPLPPSPL

NPIPB7

281

O75200
KTPPECLLTPLPPSA

NPIPA3

306

F8WFD2
KGLLCDIPPPFPNLL

NYAP2

316

Q9P242
SLKTPPECLLTPLPP

NPIPA2

281

E9PIF3
NLKTPPECVLTPLPP

NPIPB4

281

C9JG80
LKTPPECVLTPLPPS

NPIPB4

301

C9JG80
KTPPECLLTPLPPSA

NPIPB4

321

C9JG80
CKKLSPPPLPPRASI

PIK3C2B

151

O00750
PDPGAPVKLPCLPVK

PHACTR1

221

Q9C0D0
PVKLPCLPVKLSPPL

PHACTR1

226

Q9C0D0
KCLLLPPSFPPPHRQ

PRR5L

321

Q6MZQ0
NLKTPPECLLTPLPP

NPIPB11

281

E5RHQ5
LKTPPECLLTPLPPS

NPIPB11

301

E5RHQ5
KTKPLPPDPPRLECV

FNDC3A

946

Q9Y2H6
LPLEPPAAKTGCPPL

GCM1

341

Q9NP62
LCPELPPTPPHLKYL

EPOR

441

P19235
PKADSLCPRLPVPPS

SLC44A3

156

Q8N4M1
LCPRLPVPPSKSFPL

SLC44A3

161

Q8N4M1
QLRLKPPPPVAILPL

DGKZ

366

Q13574
PLFLAEPALPKGLPP

GRM1

1001

Q13255
VPRSYELLKPPPICP

IKZF3

421

Q9UKT9
NNFPPLPKFIPLKPC

SCAMP5

6

Q8TAC9
LPTAPPELCLLLPPD

SBK3

201

P0C264
LKECLFVPLPPSPLP

NPIPB6

321

E9PJ23
NIKECPLAPLPPSPL

NPIPB9

296

F8W1W9
NLKTPPECVLTPLPP

NPIPB13

281

A6NJU9
LKTPPECLLTPLPPS

NPIPB13

301

A6NJU9
KTPPECLLTPLPPSA

NPIPB13

321

A6NJU9
NLKTPPECLLTPLPP

NPIPA7

281

E9PJI5
NLKTPPECLLTPLPP

NPIPA8

281

P0DM63
RPKFSLPPPLQLIPE

FES

436

P07332
APPLVLPPKELALPL

TAF3

651

Q5VWG9
PLKAPRENPCFPLPA

SERF1A

56

O75920
IDPPLAPLPRPCMSI

FER1L5

11

A0AVI2
NLKTPPECLLTPLPP

NPIPA5

281

E9PKD4
GCISPSLPPPPLKLL

RREB1

536

Q92766
KCPTEVLLTPPTPLP

STAC2

61

Q6ZMT1
PPAKLPCLSPEALLV

nan

276

A8MX80
NLKTPPECLLTPLPP

NPIPB2

296

A6NJ64
PPAKLPCLSPEALLV

nan

246

A8MV72
PPAKLPCLSPEALLV

nan

276

Q8N9G6
PPAKFPCLSPEALLV

nan

276

A8MUI8
PPAKLPCLSPEALLV

nan

276

A8MUA0
PAPTPPLLVALLCLF

TNK1

211

Q13470
PPRLPLAVSLKPPFL

ZDHHC8

256

Q9ULC8
APSSLPPLPPKVLVC

TREML1

261

Q86YW5
PFLIPSPPICQTEPL

TET2

16

Q6N021
PALAPEPPLIPKLLV

WDR81

596

Q562E7
PLPIFQEVPFAPPLC

TEX38

146

Q6PEX7
IFCLLPPLPEIPKGV

KDM5C

351

P41229