Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	activin receptor activity, type I	ACVR1 ACVR1B ACVRL1	1.10e-06	5	97	3	GO:0016361
GeneOntologyMolecularFunction	serine-type endopeptidase activity	OVCH2 RHBDF2 PRSS41 CTSC PRSS29P LONP1 PARL TPSG1	4.07e-06	190	97	8	GO:0004252
GeneOntologyMolecularFunction	serine-type peptidase activity	OVCH2 RHBDF2 PRSS41 CTSC PRSS29P LONP1 PARL TPSG1	7.64e-06	207	97	8	GO:0008236
GeneOntologyMolecularFunction	serine hydrolase activity	OVCH2 RHBDF2 PRSS41 CTSC PRSS29P LONP1 PARL TPSG1	9.10e-06	212	97	8	GO:0017171
GeneOntologyMolecularFunction	activin receptor activity	ACVR1 ACVR1B ACVRL1	9.14e-06	9	97	3	GO:0017002
GeneOntologyMolecularFunction	activin binding	ACVR1 ACVR1B ACVRL1	2.37e-05	12	97	3	GO:0048185
GeneOntologyMolecularFunction	endopeptidase activity	OVCH2 RHBDF2 PRSS41 CTSC SPPL2B CAPN13 PRSS29P LONP1 PARL TPSG1	4.58e-05	430	97	10	GO:0004175
GeneOntologyMolecularFunction	ATP:phosphate antiporter activity	SLC25A24 SLC25A25	6.98e-05	3	97	2	GO:0140987
GeneOntologyMolecularFunction	transmembrane receptor protein serine/threonine kinase activity	ACVR1 ACVR1B ACVRL1	1.19e-04	20	97	3	GO:0004675
GeneOntologyMolecularFunction	signaling receptor complex adaptor activity	FRS3 SHANK3 SHANK2 LAT	1.37e-04	54	97	4	GO:0030159
GeneOntologyMolecularFunction	synaptic receptor adaptor activity	SHANK3 SHANK2	1.39e-04	4	97	2	GO:0030160
GeneOntologyMolecularFunction	AMPA glutamate receptor activity	GRIA3 GRIA4	1.39e-04	4	97	2	GO:0004971
GeneOntologyMolecularFunction	transforming growth factor beta receptor activity, type I	ACVR1 ACVRL1	2.31e-04	5	97	2	GO:0005025
GeneOntologyMolecularFunction	organophosphate:phosphate antiporter activity	SLC25A24 SLC25A25	4.83e-04	7	97	2	GO:0015315
GeneOntologyMolecularFunction	BMP receptor activity	ACVR1 ACVRL1	6.42e-04	8	97	2	GO:0098821
GeneOntologyMolecularFunction	transmembrane receptor protein kinase activity	NTRK1 ACVR1 ACVR1B ACVRL1	7.84e-04	85	97	4	GO:0019199
GeneOntologyMolecularFunction	growth factor binding	RHBDF2 NTRK1 ACVR1 ACVR1B ACVRL1	9.87e-04	156	97	5	GO:0019838
GeneOntologyMolecularFunction	structural constituent of postsynaptic density	SHANK3 SHANK2	1.25e-03	11	97	2	GO:0098919
GeneOntologyMolecularFunction	peptidase activity	OVCH2 RHBDF2 PRSS41 CTSC SPPL2B CAPN13 PRSS29P LONP1 PARL TPSG1	1.29e-03	654	97	10	GO:0008233
GeneOntologyMolecularFunction	transforming growth factor beta receptor activity	ACVR1 ACVRL1	1.76e-03	13	97	2	GO:0005024
GeneOntologyMolecularFunction	structural constituent of postsynaptic specialization	SHANK3 SHANK2	1.76e-03	13	97	2	GO:0098879
GeneOntologyMolecularFunction	ATP transmembrane transporter activity	SLC25A24 SLC25A25	2.05e-03	14	97	2	GO:0005347
GeneOntologyMolecularFunction	oxysterol binding	OSBP SMO	2.68e-03	16	97	2	GO:0008142
GeneOntologyCellularComponent	BMP receptor complex	ACVR1 ACVRL1	1.32e-04	4	99	2	GO:0070724
GeneOntologyCellularComponent	activin receptor complex	ACVR1 ACVR1B	3.29e-04	6	99	2	GO:0048179
MousePheno	abnormal thermal nociception	NTRK1 CTSC GRIA3 GRIA4 TRIM14 SHANK3 ZNF106	2.03e-05	168	70	7	MP:0002733
Domain	SH3	MYO1E CD2AP PSTPIP1 SHANK3 RUSC2 SHANK2 MAP3K21 DNMBP VAV1 VAV2	1.10e-07	216	92	10	SM00326
Domain	SH3	MYO1E CD2AP PSTPIP1 SHANK3 RUSC2 SHANK2 MAP3K21 DNMBP VAV1 VAV2	1.10e-07	216	92	10	PS50002
Domain	SH3_domain	MYO1E CD2AP PSTPIP1 SHANK3 RUSC2 SHANK2 MAP3K21 DNMBP VAV1 VAV2	1.30e-07	220	92	10	IPR001452
Domain	GS	ACVR1 ACVR1B ACVRL1	3.99e-06	7	92	3	SM00467
Domain	GS_dom	ACVR1 ACVR1B ACVRL1	3.99e-06	7	92	3	IPR003605
Domain	GS	ACVR1 ACVR1B ACVRL1	3.99e-06	7	92	3	PS51256
Domain	TGF_beta_GS	ACVR1 ACVR1B ACVRL1	3.99e-06	7	92	3	PF08515
Domain	SH3_2	CD2AP SHANK3 RUSC2 SHANK2 DNMBP VAV2	4.15e-06	86	92	6	IPR011511
Domain	SH3_2	CD2AP SHANK3 RUSC2 SHANK2 DNMBP VAV2	4.15e-06	86	92	6	PF07653
Domain	SH3_1	MYO1E CD2AP PSTPIP1 MAP3K21 DNMBP VAV1 VAV2	1.66e-05	164	92	7	PF00018
Domain	TGFB_receptor	ACVR1 ACVR1B ACVRL1	2.46e-05	12	92	3	IPR000333
Domain	Vav	VAV1 VAV2	7.18e-05	3	92	2	IPR028530
Domain	Graves_DC	SLC25A24 SLC25A25	1.43e-04	4	92	2	IPR002167
Domain	CAMSAP_CH	VAV1 VAV2	4.96e-04	7	92	2	PF11971
Domain	CAMSAP_CH	VAV1 VAV2	4.96e-04	7	92	2	IPR022613
Domain	SH3_9	CD2AP PSTPIP1 MAP3K21 DNMBP	5.95e-04	78	92	4	PF14604
Domain	GPS	ADGRG2 PKD1 ADGRA3	6.20e-04	34	92	3	SM00303
Domain	Peptidase_S54_rhomboid	RHBDF2 PARL	6.59e-04	8	92	2	IPR002610
Domain	N6_MTASE	HEMK1 MGAM2	6.59e-04	8	92	2	PS00092
Domain	GPS	ADGRG2 PKD1 ADGRA3	6.75e-04	35	92	3	PF01825
Domain	GPS	ADGRG2 PKD1 ADGRA3	7.34e-04	36	92	3	PS50221
Domain	GPS	ADGRG2 PKD1 ADGRA3	7.96e-04	37	92	3	IPR000203
Domain	Rhomboid	RHBDF2 PARL	8.45e-04	9	92	2	PF01694
Domain	Peptidase_S54_rhomboid_dom	RHBDF2 PARL	8.45e-04	9	92	2	IPR022764
Domain	-	RHBDF2 PARL	8.45e-04	9	92	2	1.20.1540.10
Domain	GDS_CDC24_CS	DNMBP VAV1 VAV2	9.30e-04	39	92	3	IPR001331
Domain	Activin_recp	ACVR1 ACVR1B	1.05e-03	10	92	2	IPR000472
Domain	Activin_recp	ACVR1 ACVR1B	1.05e-03	10	92	2	PF01064
Domain	MORN	JPH4 MORN3	2.10e-03	14	92	2	SM00698
Domain	MORN	JPH4 MORN3	2.42e-03	15	92	2	IPR003409
Domain	MORN	JPH4 MORN3	2.42e-03	15	92	2	PF02493
Domain	GPCR_2_secretin-like	ADGRG2 SMO ADGRA3	3.23e-03	60	92	3	IPR000832
Domain	GPCR_2-like	ADGRG2 SMO ADGRA3	3.23e-03	60	92	3	IPR017981
Domain	G_PROTEIN_RECEP_F2_4	ADGRG2 SMO ADGRA3	3.39e-03	61	92	3	PS50261
Domain	Iontro_rcpt	GRIA3 GRIA4	3.49e-03	18	92	2	IPR001320
Domain	Lig_chan-Glu_bd	GRIA3 GRIA4	3.49e-03	18	92	2	PF10613
Domain	Iono_rcpt_met	GRIA3 GRIA4	3.49e-03	18	92	2	IPR001508
Domain	Glu/Gly-bd	GRIA3 GRIA4	3.49e-03	18	92	2	IPR019594
Domain	Lig_chan-Glu_bd	GRIA3 GRIA4	3.49e-03	18	92	2	SM00918
Domain	Lig_chan	GRIA3 GRIA4	3.49e-03	18	92	2	PF00060
Domain	PBPe	GRIA3 GRIA4	3.49e-03	18	92	2	SM00079
Domain	DH_1	DNMBP VAV1 VAV2	3.71e-03	63	92	3	PS00741
Domain	RhoGEF	DNMBP VAV1 VAV2	4.60e-03	68	92	3	SM00325
Pathway	KEGG_MEDICUS_PATHOGEN_YERSINIA_YOPH_TO_TCR_NFAT_SIGNALING_PATHWAY	LAT VAV1 VAV2	1.22e-06	5	71	3	M48994
Pathway	KEGG_MEDICUS_REFERENCE_TCR_PLCG_ITPR_SIGNALING_PATHWAY	LAT VAV1 VAV2	1.12e-04	19	71	3	M47733
Pubmed	Activin receptor-like kinases: a novel subclass of cell-surface receptors with predicted serine/threonine kinase activity.	ACVR1 ACVR1B ACVRL1	2.37e-07	5	101	3	8397373
Pubmed	Comprehensive analysis of interactions between the Src-associated protein in mitosis of 68 kDa and the human Src-homology 3 proteome.	CD2AP PSTPIP1 RUSC2 DNMBP VAV1	6.35e-07	56	101	5	22745667
Pubmed	SB-431542 is a potent and specific inhibitor of transforming growth factor-beta superfamily type I activin receptor-like kinase (ALK) receptors ALK4, ALK5, and ALK7.	ACVR1 ACVR1B ACVRL1	8.25e-07	7	101	3	12065756
Pubmed	Regulation of NK cell-mediated cytotoxicity by the adaptor protein 3BP2.	LAT VAV1 VAV2	1.32e-06	8	101	3	11390470
Pubmed	Human retroviral gag- and gag-pol-like proteins interact with the transforming growth factor-beta receptor activin receptor-like kinase 1.	ACVR1 ACVR1B ACVRL1	2.81e-06	10	101	3	15611116
Pubmed	Mouse chromosome 17A3.3 contains 13 genes that encode functional tryptic-like serine proteases with distinct tissue and cell expression patterns.	PRSS41 PRSS29P TPSG1	2.81e-06	10	101	3	14583634
Pubmed	Modulation of activin signal transduction by inhibin B and inhibin-binding protein (INhBP).	ACVR1 ACVR1B ACVRL1	2.81e-06	10	101	3	11266516
Pubmed	Human BAMBI cooperates with Smad7 to inhibit transforming growth factor-beta signaling.	ACVR1 ACVR1B ACVRL1	3.86e-06	11	101	3	19758997
Pubmed	Murine gamma-herpesvirus 68 latency protein M2 binds to Vav signaling proteins and inhibits B-cell receptor-induced cell cycle arrest and apoptosis in WEHI-231 B cells.	VAV1 VAV2	8.35e-06	2	101	2	16150693
Pubmed	Vav1 and Vav2 play different roles in macrophage migration and cytoskeletal organization.	VAV1 VAV2	8.35e-06	2	101	2	16137676
Pubmed	Characterization of the Shank family of synaptic proteins. Multiple genes, alternative splicing, and differential expression in brain and development.	SHANK3 SHANK2	8.35e-06	2	101	2	10506216
Pubmed	Isolation and characterization of murine vav2, a member of the vav family of proto-oncogenes.	VAV1 VAV2	8.35e-06	2	101	2	8710375
Pubmed	Compensation between Vav-1 and Vav-2 in B cell development and antigen receptor signaling.	VAV1 VAV2	8.35e-06	2	101	2	11376343
Pubmed	Kinetic properties of human AMPA-type glutamate receptors expressed in HEK293 cells.	GRIA3 GRIA4	8.35e-06	2	101	2	12670305
Pubmed	Strongly reduced alloreactivity and long-term survival times of cardiac allografts in Vav1- and Vav1/Vav2-knockout mice.	VAV1 VAV2	8.35e-06	2	101	2	17326776
Pubmed	Modulation of Lon protease activity and aconitase turnover during aging and oxidative stress.	LONP1 SOD2	8.35e-06	2	101	2	12459471
Pubmed	Signal transduction through Vav-2 participates in humoral immune responses and B cell maturation.	VAV1 VAV2	8.35e-06	2	101	2	11376342
Pubmed	Control of kinetic properties of AMPA receptor channels by nuclear RNA editing.	GRIA3 GRIA4	8.35e-06	2	101	2	7992055
Pubmed	Genomic organization of a mouse type I activin receptor.	ACVR1 ACVR1B	8.35e-06	2	101	2	7639738
Pubmed	Differentially altered social dominance- and cooperative-like behaviors in Shank2- and Shank3-mutant mice.	SHANK3 SHANK2	8.35e-06	2	101	2	33126897
Pubmed	Elimination of redundant synaptic inputs in the absence of synaptic strengthening.	GRIA3 GRIA4	8.35e-06	2	101	2	22090494
Pubmed	Regulatory and signaling properties of the Vav family.	VAV1 VAV2	8.35e-06	2	101	2	10669724
Pubmed	Role of substrates and products of PI 3-kinase in regulating activation of Rac-related guanosine triphosphatases by Vav.	VAV1 VAV2	8.35e-06	2	101	2	9438848
Pubmed	The TrkAIII oncoprotein inhibits mitochondrial free radical ROS-induced death of SH-SY5Y neuroblastoma cells by augmenting SOD2 expression and activity at the mitochondria, within the context of a tumour stem cell-like phenotype.	NTRK1 SOD2	8.35e-06	2	101	2	24736663
Pubmed	Structure and function of vav.	VAV1 VAV2	8.35e-06	2	101	2	9115846
Pubmed	Recognition and activation of Rho GTPases by Vav1 and Vav2 guanine nucleotide exchange factors.	VAV1 VAV2	8.35e-06	2	101	2	15850391
Pubmed	Absence seizures in C3H/HeJ and knockout mice caused by mutation of the AMPA receptor subunit Gria4.	GRIA3 GRIA4	8.35e-06	2	101	2	18316356
Pubmed	Expression profiles of the autism-related SHANK proteins in the human brain.	SHANK3 SHANK2	8.35e-06	2	101	2	37953224
Pubmed	The Adaptor Protein CD2AP Is a Coordinator of Neurotrophin Signaling-Mediated Axon Arbor Plasticity.	NTRK1 CD2AP	8.35e-06	2	101	2	27076424
Pubmed	Shank2/3 double knockout-based screening of cortical subregions links the retrosplenial area to the loss of social memory in autism spectrum disorders.	SHANK3 SHANK2	8.35e-06	2	101	2	36100669
Pubmed	Autistic-like behaviours and hyperactivity in mice lacking ProSAP1/Shank2.	SHANK3 SHANK2	8.35e-06	2	101	2	22699619
Pubmed	Proline-rich synapse-associated protein-1 and 2 (ProSAP1/Shank2 and ProSAP2/Shank3)-scaffolding proteins are also present in postsynaptic specializations of the peripheral nervous system.	SHANK3 SHANK2	8.35e-06	2	101	2	20800661
Pubmed	Chromosomal localization of three human genes encoding members of the TGF-beta superfamily of type I serine/threonine kinase receptors.	ACVR1 ACVR1B	8.35e-06	2	101	2	9501322
Pubmed	Altered Intestinal Morphology and Microbiota Composition in the Autism Spectrum Disorders Associated SHANK3 Mouse Model.	SHANK3 SHANK2	8.35e-06	2	101	2	31052177
Pubmed	Vav proteins are required for B-lymphocyte responses to LPS.	VAV1 VAV2	8.35e-06	2	101	2	15811961
Pubmed	Selective Localization of Shanks to VGLUT1-Positive Excitatory Synapses in the Mouse Hippocampus.	SHANK3 SHANK2	8.35e-06	2	101	2	27199660
Pubmed	SHANK3 in vagal sensory neurons regulates body temperature, systemic inflammation, and sepsis.	SHANK3 SHANK2	8.35e-06	2	101	2	36845137
Pubmed	GluA4 is indispensable for driving fast neurotransmission across a high-fidelity central synapse.	GRIA3 GRIA4	8.35e-06	2	101	2	21690196
Pubmed	TSC-22 promotes transforming growth factor β-mediated cardiac myofibroblast differentiation by antagonizing Smad7 activity.	ACVR1 ACVR1B ACVRL1	8.45e-06	14	101	3	21791611
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	ENGASE RHBDF2 MYO1E PIEZO1 LAMC3 SPPL2B BIRC6 SHANK2 PKD1 HERC2 SNAPC4 MRPL46 DNMBP	1.93e-05	1105	101	13	35748872
Pubmed	Vav family proteins are required for optimal regulation of PLCgamma2 by integrin alphaIIbbeta3.	VAV1 VAV2	2.50e-05	3	101	2	17054426
Pubmed	The number and distribution of AMPA receptor channels containing fast kinetic GluA3 and GluA4 subunits at auditory nerve synapses depend on the target cells.	GRIA3 GRIA4	2.50e-05	3	101	2	28397107
Pubmed	The Shank family of scaffold proteins.	SHANK3 SHANK2	2.50e-05	3	101	2	10806096
Pubmed	Immunosuppression-Independent Role of Regulatory T Cells against Hypertension-Driven Renal Dysfunctions.	VAV1 VAV2	2.50e-05	3	101	2	26240279
Pubmed	The Rho exchange factors Vav2 and Vav3 favor skin tumor initiation and promotion by engaging extracellular signaling loops.	VAV1 VAV2	2.50e-05	3	101	2	23935450
Pubmed	The role of activin type I receptors in activin A-induced growth arrest and apoptosis in mouse B-cell hybridoma cells.	ACVR1 ACVR1B	2.50e-05	3	101	2	9884026
Pubmed	Study on GRIA2, GRIA3 and GRIA4 genes highlights a positive association between schizophrenia and GRIA3 in female patients.	GRIA3 GRIA4	2.50e-05	3	101	2	18163426
Pubmed	Translational neurobiology in Shank mutant mice--model systems for neuropsychiatric disorders.	SHANK3 SHANK2	2.50e-05	3	101	2	25917711
Pubmed	Blockage of Ca(2+)-permeable AMPA receptors suppresses migration and induces apoptosis in human glioblastoma cells.	GRIA3 GRIA4	2.50e-05	3	101	2	12172541
Pubmed	Retroviral proteins that interact with the host cell cytoskeleton.	VAV1 VAV2	2.50e-05	3	101	2	17707624
Pubmed	Vav exchange factor counteracts the HIV-1 Nef-mediated decrease of plasma membrane GM1 and NF-AT activity in T cells.	VAV1 VAV2	2.50e-05	3	101	2	12884293
Pubmed	VAV2 signaling promotes regenerative proliferation in both cutaneous and head and neck squamous cell carcinoma.	VAV1 VAV2	2.50e-05	3	101	2	32963234
Pubmed	Vav1/2/3-null mice define an essential role for Vav family proteins in lymphocyte development and activation but a differential requirement in MAPK signaling in T and B cells.	VAV1 VAV2	2.50e-05	3	101	2	14623913
Pubmed	TGFbeta/BMP type I receptors ALK1 and ALK2 are essential for BMP9-induced osteogenic signaling in mesenchymal stem cells.	ACVR1 ACVRL1	2.50e-05	3	101	2	20628059
Pubmed	Modeling autism by SHANK gene mutations in mice.	SHANK3 SHANK2	2.50e-05	3	101	2	23583105
Pubmed	Phosphotyrosine-dependent activation of Rac-1 GDP/GTP exchange by the vav proto-oncogene product.	VAV1 VAV2	2.50e-05	3	101	2	8990121
Pubmed	Identification of the mitochondrial ATP-Mg/Pi transporter. Bacterial expression, reconstitution, functional characterization, and tissue distribution.	SLC25A24 SLC25A25	2.50e-05	3	101	2	15123600
Pubmed	Vav2 pharmaco-mimetic mice reveal the therapeutic value and caveats of the catalytic inactivation of a Rho exchange factor.	VAV1 VAV2	2.50e-05	3	101	2	32528129
Pubmed	Functional and physical interactions of Syk family kinases with the Vav proto-oncogene product.	VAV1 VAV2	2.50e-05	3	101	2	8986718
Pubmed	Human immunodeficiency virus type 1 Nef recruits the guanine exchange factor Vav1 via an unexpected interface into plasma membrane microdomains for association with p21-activated kinase 2 activity.	VAV1 VAV2	2.50e-05	3	101	2	18094167
Pubmed	Heterogeneity of Cell Surface Glutamate and GABA Receptor Expression in Shank and CNTN4 Autism Mouse Models.	SHANK3 SHANK2	2.50e-05	3	101	2	29970989
Pubmed	Synaptic AMPA receptor plasticity and behavior.	GRIA3 GRIA4	2.50e-05	3	101	2	19217372
Pubmed	Identification of a novel human subfamily of mitochondrial carriers with calcium-binding domains.	SLC25A24 SLC25A25	2.50e-05	3	101	2	15054102
Pubmed	S100B dysregulation during brain development affects synaptic SHANK protein networks via alteration of zinc homeostasis.	SHANK3 SHANK2	2.50e-05	3	101	2	34741005
Pubmed	A Paradoxical Tumor-Suppressor Role for the Rac1 Exchange Factor Vav1 in T Cell Acute Lymphoblastic Leukemia.	VAV1 VAV2	2.50e-05	3	101	2	29136506
Pubmed	Glucagon regulation of oxidative phosphorylation requires an increase in matrix adenine nucleotide content through Ca2+ activation of the mitochondrial ATP-Mg/Pi carrier SCaMC-3.	SLC25A24 SLC25A25	2.50e-05	3	101	2	23344948
Pubmed	Dynamic Change of Shanks Gene mRNA Expression and DNA Methylation in Epileptic Rat Model and Human Patients.	SHANK3 SHANK2	2.50e-05	3	101	2	32564287
Pubmed	Shotgun sequencing of the human transcriptome with ORF expressed sequence tags.	COL7A1 RHBDF2 PIEZO1 PSTPIP1 CAPN13 SHANK2 TNRC6A HERC2 RSKR	3.43e-05	552	101	9	10737800
Pubmed	Vav proteins are necessary for correct differentiation of mouse cecal and colonic enterocytes.	VAV1 VAV2	4.99e-05	4	101	2	19139088
Pubmed	A phylogenetic analysis reveals an unusual sequence conservation within introns involved in RNA editing.	GRIA3 GRIA4	4.99e-05	4	101	2	10688364
Pubmed	Phospholipase C-gamma2 and Vav cooperate within signaling microclusters to propagate B cell spreading in response to membrane-bound antigen.	VAV1 VAV2	4.99e-05	4	101	2	18362175
Pubmed	BMP type I receptor ALK2 is required for angiotensin II-induced cardiac hypertrophy.	ACVR1 ACVRL1	4.99e-05	4	101	2	26873969
Pubmed	Signalling through AMPA receptors on oligodendrocyte precursors promotes myelination by enhancing oligodendrocyte survival.	GRIA3 GRIA4	4.99e-05	4	101	2	28608780
Pubmed	Vav1, but not Vav2, contributes to platelet aggregation by CRP and thrombin, but neither is required for regulation of phospholipase C.	VAV1 VAV2	4.99e-05	4	101	2	12411320
Pubmed	Neutrophil-mediated oxidative burst and host defense are controlled by a Vav-PLCgamma2 signaling axis in mice.	VAV1 VAV2	4.99e-05	4	101	2	17932569
Pubmed	AMPA receptor subunits expressed by single astrocytes in the juvenile mouse hippocampus.	GRIA3 GRIA4	4.99e-05	4	101	2	9221927
Pubmed	Interaction proteomics reveals brain region-specific AMPA receptor complexes.	GRIA3 GRIA4	4.99e-05	4	101	2	25337787
Pubmed	Auditory sensitivity regulation via rapid changes in expression of surface AMPA receptors.	GRIA3 GRIA4	4.99e-05	4	101	2	17828255
Pubmed	Murine implantation serine proteinases 1 and 2: structure, function and evolution.	PRSS29P TPSG1	4.99e-05	4	101	2	16257142
Pubmed	The N-terminal domain modulates α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptor desensitization.	GRIA3 GRIA4	4.99e-05	4	101	2	24652293
Pubmed	Electrophysiological properties of AMPA receptors are differentially modulated depending on the associated member of the TARP family.	GRIA3 GRIA4	4.99e-05	4	101	2	17409242
Pubmed	SHANK3 gene mutations associated with autism facilitate ligand binding to the Shank3 ankyrin repeat region.	SHANK3 SHANK2	4.99e-05	4	101	2	23897824
Pubmed	The Rho/Rac exchange factor Vav2 controls nitric oxide-dependent responses in mouse vascular smooth muscle cells.	VAV1 VAV2	4.99e-05	4	101	2	20038798
Pubmed	The physiology and pathophysiology of inhibin, activin and follistatin in female reproduction.	ACVR1 ACVR1B	4.99e-05	4	101	2	12032389
Pubmed	Lack of association between NLGN3, NLGN4, SHANK2 and SHANK3 gene variants and autism spectrum disorder in a Chinese population.	SHANK3 SHANK2	4.99e-05	4	101	2	23468870
Pubmed	Activin A accelerates the progression of fetal oocytes throughout meiosis and early oogenesis in the mouse.	ACVR1 ACVR1B	4.99e-05	4	101	2	26083127
Pubmed	Vav3 collaborates with p190-BCR-ABL in lymphoid progenitor leukemogenesis, proliferation, and survival.	VAV1 VAV2	4.99e-05	4	101	2	22692505
Pubmed	Transcriptional factor aryl hydrocarbon receptor (Ahr) controls cardiovascular and respiratory functions by regulating the expression of the Vav3 proto-oncogene.	VAV1 VAV2	4.99e-05	4	101	2	21115475
Pubmed	Aberrant formation of glutamate receptor complexes in hippocampal neurons of mice lacking the GluR2 AMPA receptor subunit.	GRIA3 GRIA4	4.99e-05	4	101	2	14561864
Pubmed	Clustering of AMPA receptors by the synaptic PDZ domain-containing protein PICK1.	GRIA3 GRIA4	4.99e-05	4	101	2	10027300
Pubmed	Vav proteins control MyD88-dependent oxidative burst.	VAV1 VAV2	4.99e-05	4	101	2	17158234
Pubmed	Chromosomal localization of human glutamate receptor genes.	GRIA3 GRIA4	4.99e-05	4	101	2	1319477
Pubmed	The Wiskott-Aldrich syndrome protein acts downstream of CD2 and the CD2AP and PSTPIP1 adaptors to promote formation of the immunological synapse.	CD2AP PSTPIP1	4.99e-05	4	101	2	12530983
Pubmed	AMPA receptors regulate dynamic equilibrium of presynaptic terminals in mature hippocampal networks.	GRIA3 GRIA4	4.99e-05	4	101	2	12692557
Pubmed	Vav proteins regulate the plasma cell program and secretory Ig production.	VAV1 VAV2	4.99e-05	4	101	2	17142761
Pubmed	Flip and flop splice variants of AMPA receptor subunits in the spinal cord of amyotrophic lateral sclerosis.	GRIA3 GRIA4	4.99e-05	4	101	2	12125045
Pubmed	X-linked inhibitor of apoptosis protein functions as a cofactor in transforming growth factor-beta signaling.	ACVR1B ACVRL1	4.99e-05	4	101	2	11356828
Pubmed	Alk2/ACVR1 and Alk3/BMPR1A Provide Essential Function for Bone Morphogenetic Protein-Induced Retinal Angiogenesis.	ACVR1 ACVRL1	4.99e-05	4	101	2	28232325
Pubmed	The Shank family of postsynaptic density proteins interacts with and promotes synaptic accumulation of the beta PIX guanine nucleotide exchange factor for Rac1 and Cdc42.	SHANK3 SHANK2	4.99e-05	4	101	2	12626503
Pubmed	Altered glutamate protein co-expression network topology linked to spine loss in the auditory cortex of schizophrenia.	GRIA3 GRIA4	4.99e-05	4	101	2	25433904
Cytoband	Ensembl 112 genes in cytogenetic band chr19p13	CPAMD8 SCAMP4 IQCN SPPL2B LONP1 RASAL3 FDX2 MYDGF VAV1	6.90e-05	797	101	9	chr19p13
GeneFamily	Type 1 receptor serine/threonine kinases	ACVR1 ACVR1B ACVRL1	1.40e-06	7	63	3	345
GeneFamily	Proteases, serine	PRSS41 PRSS29P LONP1 TPSG1	6.83e-05	63	63	4	738
GeneFamily	Glutamate ionotropic receptor AMPA type subunits	GRIA3 GRIA4	7.14e-05	4	63	2	1200
GeneFamily	Hyalectan proteoglycans\|V-set domain containing\|Sushi domain containing\|C-type lectin domain containing	ATRN CHODL PKD1	3.91e-04	41	63	3	1298
GeneFamily	Rhomboid family	RHBDF2 PARL	1.06e-03	14	63	2	926
GeneFamily	Pleckstrin homology domain containing\|Rho guanine nucleotide exchange factors\|C2 domain containing	DNMBP VAV1 VAV2	1.58e-03	66	63	3	722
ToppCell	PCW_05-06-Hematologic_ErythroMegGranulo-Hem_Granulocytic-im_neutrophils_(9)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	PLB1 PSTPIP1 APOBR CD1C RASAL3 VAV1	3.84e-06	183	101	6	aed12b743334f3813db0c70d4fe7df90e0673f54
ToppCell	LPS_IL1RA_TNF-Hematopoietic_Lymphocytic-Lymphocytic_NK/T-iNKT-MAIT\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	MYO1E NTRK1 PSTPIP1 APOBR RASAL3 LAT	6.21e-06	199	101	6	c23a53a20487a8abfeb91fa5fc9c06823dd657e9
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW16-Neuroepithelial\|GW16 / Sample Type, Dataset, Time_group, and Cell type.	RHBDF2 PIEZO1 LAMC3 BCL2A1 ACVRL1 RASAL3	6.39e-06	200	101	6	25f4c051c2e869481f33c22ad54de97efac444ad
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW16-Neuroepithelial-Proteoglycan-expressing_cell\|GW16 / Sample Type, Dataset, Time_group, and Cell type.	RHBDF2 PIEZO1 LAMC3 BCL2A1 ACVRL1 RASAL3	6.39e-06	200	101	6	da45a85a4667965b24ba824af871157af5b4cd19
ToppCell	TCGA-Lung-Primary_Tumor-Lung_Carcinoma-Lung_Adenocarcinoma_Mixed_Subtype-6\|TCGA-Lung / Sample_Type by Project: Shred V9	OVCH2 LAMC3 SHANK3 CCM2L TDRD6	1.02e-05	126	101	5	b49b15ba1458488f98d54e87100257a12ee34076
ToppCell	wk_20-22-Epithelial-Proximal_epithelial-SMG_basal_1\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	COL7A1 CPAMD8 SHANK2 PAX1 MGAM2	3.03e-05	158	101	5	adad97e6cf479d42791c5ba9cbc5f15f469322bf
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Immune-Myeloid-Granulocytic-Mast_Cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	NTRK1 TDRD6 TPSG1 VAV1 KRT10-AS1	3.31e-05	161	101	5	c54010d88f1ecb6e0235bb66084876a4d5bf1ecd
ToppCell	TCGA-Kidney-Solid_Tissue_Normal-Kidney-Kidney_normal_tissue\|TCGA-Kidney / Sample_Type by Project: Shred V9	ENPP6 CPAMD8 JPH4 OVCH2 WNT8B	3.41e-05	162	101	5	a0367e9af78e4699b9d89d3e0597589e644f844c
ToppCell	TCGA-Kidney-Solid_Tissue_Normal-Kidney\|TCGA-Kidney / Sample_Type by Project: Shred V9	ENPP6 CPAMD8 JPH4 OVCH2 WNT8B	3.41e-05	162	101	5	d007ec42d6458431f6c490df61de7a9caef857f0
ToppCell	TCGA-Kidney-Solid_Tissue_Normal\|TCGA-Kidney / Sample_Type by Project: Shred V9	ENPP6 CPAMD8 JPH4 OVCH2 WNT8B	3.41e-05	162	101	5	65549ffdbfe8619693345db78e6ddbdde7b742c9
ToppCell	LPS_only-Epithelial_airway-Club_cells-Airway\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ANKRD65 KRT78 CAPN13 RNF39 MORN3	3.62e-05	164	101	5	b1243b10591e1e15a94952e39ffbf382eae6aae8
ToppCell	LPS_only-Epithelial_airway-Club_cells\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ANKRD65 KRT78 CAPN13 RNF39 MORN3	3.62e-05	164	101	5	c5b2001280a43da855017361a3f6071a0e492848
ToppCell	LPS_only-Epithelial_airway\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ANKRD65 KRT78 CAPN13 RNF39 MORN3	3.62e-05	164	101	5	56e6934e6c7503a300d7be06762d45a1d6f1ae0f
ToppCell	droplet-Kidney-KIDNEY-1m-Myeloid-nan\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ENGASE CTSC PSTPIP1 RASAL3 VAV1	4.41e-05	171	101	5	d9ad6a3bce3556abd24af1630bf4a99594437c3a
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Outer_Medullary_Collecting_Duct_Principal_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	MYO1E CD2AP SHANK2 MAP3K21 VAV2	5.78e-05	181	101	5	aa233b652921848af2257cc3687a7a09c3acfb67
ToppCell	PCW_05-06-Mesenchymal-Mesenchymal_fibroblastic-mes_immature_adventitial_fibro_(9)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	DIPK1C JPH4 GRIA3 GRIA4 BCL2A1	6.57e-05	186	101	5	8915436d09775f2828a7678af203b1082b36e21c
ToppCell	10x3'2.3-week_17-19-Endothelial-stroma-proliferating_EC\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	MYO1E ACVRL1 SHANK3 CCM2L TDRD6	6.57e-05	186	101	5	a844d4f79e0ad5d6c60a4488ffd8f4f21b7eed04
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	CPAMD8 MYO1E PIEZO1 MAP3K21 VAV2	7.09e-05	189	101	5	fc88c51ace7d883c01617f3f9b5fab70cc91cc09
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Myeloid-Macrophage_Dendritic\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	PLB1 TMEM144 PSTPIP1 TRIM14 VAV1	7.45e-05	191	101	5	51f5af610983aa73b9f4ece6f27d281ebff89a04
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Myeloid-Macrophage_Dendritic-M2_Macrophage\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	PLB1 TMEM144 PSTPIP1 TRIM14 VAV1	7.45e-05	191	101	5	8fd6bdc9d2b1c8d364221d7bc68d03921b668ab5
ToppCell	Control-Epithelial-Club\|Control / Disease state, Lineage and Cell class	CPAMD8 CAPN13 SHANK2 RNF39 ADGRA3	7.64e-05	192	101	5	d84ed1ea4a03edaa18c804f75afb03bd7b1f0e16
ToppCell	PCW_13-14-Endothelial-Endothelial_mature-endo_venous_(13)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	JPH4 CHODL ACVRL1 SHANK3 CCM2L	7.82e-05	193	101	5	84d1c1b7d3a1cb80f175527e3c89a2c3da7657f7
ToppCell	PCW_10-12-Endothelial-Endothelial_mature-endo_venous_(13)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	JPH4 CHODL ACVRL1 SHANK3 CCM2L	8.02e-05	194	101	5	efd5efed060edb7f24d59600981bb60ec28ac2ef
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	CPAMD8 MYO1E PIEZO1 CD2AP SHANK2	8.02e-05	194	101	5	04bfc555743f7d8821439d05ae442d15e9886c59
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	CPAMD8 MYO1E PIEZO1 CD2AP SHANK2	8.02e-05	194	101	5	69bff17df4a760ccf081cf52ff04af02c14f448d
ToppCell	Tracheal-NucSeq-Endothelial-Endothelia_lymphatic-Endothelia_Lymphatic\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	PIEZO1 ACVRL1 SHANK3 CDH22 CCM2L	8.41e-05	196	101	5	09a7edf4a7defb7fe70d9777dd9500ee8421ff31
ToppCell	Tracheal-NucSeq-Endothelial-Endothelia_lymphatic\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	PIEZO1 ACVRL1 SHANK3 CDH22 CCM2L	8.41e-05	196	101	5	e50d2c66d5c5cd25fdfecdcc4c8506a1d0a85755
ToppCell	saliva-Severe-critical_progression_d12-22_with-steroid-Epithelial-Epithelial,_Airway-secretory_cell\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	PIEZO1 SLC25A25 CRLS1 NAXE CYB561	8.41e-05	196	101	5	547901c7a665770eff78eede69b8625b416c8186
ToppCell	saliva-Severe-critical_progression_d12-22_with-steroid-Epithelial-Epithelial,_Airway-secretory_cell-Epi-Secretory\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	PIEZO1 SLC25A25 CRLS1 NAXE CYB561	8.41e-05	196	101	5	6e08d7ba67da161c2dca1a17c440ffb9d9b5bc3b
ToppCell	PCW_10-12-Hematologic_Myeloid-Hem_Myeloid_monocytic-im_immature_monocyte1_(10)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	PLB1 BCL2A1 APOBR CD1C VAV1	8.83e-05	198	101	5	898be90c906ebc806a764ae6c21bbf84649b6b30
ToppCell	LPS_only-Hematopoietic_Lymphocytic-Lymphocytic_NK/T-iNKT-MAIT\|LPS_only / Treatment groups by lineage, cell group, cell type	MYO1E NTRK1 PSTPIP1 APOBR RASAL3	9.04e-05	199	101	5	b62a756b5472972156d05051a58671a58bef1f16
ToppCell	wk_20-22-Endothelial-Blood_vessel_endothelial-Venous_endo\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	JPH4 CHODL ACVRL1 SHANK3 CCM2L	9.04e-05	199	101	5	70e05d7c0c68c28754ce0e72434b205aed6287ae
ToppCell	Fetal_brain-fetalBrain_Zhong_nature-GW23-Myeloid-Microglia\|GW23 / Sample Type, Dataset, Time_group, and Cell type.	RHBDF2 CTSC PIEZO1 RASAL3 VAV1	9.04e-05	199	101	5	4ddfbcaa8054b69b3398d8c0d5fab8ae94805cb9
ToppCell	Fetal_brain-fetalBrain_Zhong_nature-GW23-Myeloid\|GW23 / Sample Type, Dataset, Time_group, and Cell type.	RHBDF2 CTSC PIEZO1 RASAL3 VAV1	9.04e-05	199	101	5	3ba48a4715d5e9387650aa97e0c5d7f7897bf380
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW23-Mesenchymal\|GW23 / Sample Type, Dataset, Time_group, and Cell type.	TMEM144 RHBDF2 CTSC PIEZO1 RASAL3	9.25e-05	200	101	5	0eccf41edefc3b8b5d0316f57d5ba572949aec2b
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW23-Mesenchymal-BMP_responsible_cell\|GW23 / Sample Type, Dataset, Time_group, and Cell type.	TMEM144 RHBDF2 CTSC PIEZO1 RASAL3	9.25e-05	200	101	5	01d707c4f8ee0daac635b7260937b1baebc6fc23
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW16-Mesenchymal\|GW16 / Sample Type, Dataset, Time_group, and Cell type.	TMEM144 RHBDF2 CTSC PIEZO1 RASAL3	9.25e-05	200	101	5	fe22f7c97f4e37dfa7881d0f1d9245c1237d873b
ToppCell	11.5-Distal-Immune\|Distal / Age, Tissue, Lineage and Cell class	PSTPIP1 APOBR CD1C RASAL3 VAV1	9.25e-05	200	101	5	c9ed06ae7a8f5a88578c8269d762d8739ae79c7f
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW10-Mesenchymal\|GW10 / Sample Type, Dataset, Time_group, and Cell type.	RHBDF2 PIEZO1 ACVRL1 RASAL3 CCM2L	9.25e-05	200	101	5	5c638c80661017c85f9390f1b398ac7728c8f001
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW10-Mesenchymal-BMP_responsible_cell\|GW10 / Sample Type, Dataset, Time_group, and Cell type.	RHBDF2 PIEZO1 ACVRL1 RASAL3 CCM2L	9.25e-05	200	101	5	604a88633d4162337e394155c7346dbdef8b9f5a
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW16-Mesenchymal-BMP_responsible_cell\|GW16 / Sample Type, Dataset, Time_group, and Cell type.	TMEM144 RHBDF2 CTSC PIEZO1 RASAL3	9.25e-05	200	101	5	26251ed8c7fa7e87973d6f59bd398c88ad025395
ToppCell	(7)_Epithelial_cells-(7)_Epithelial-C_(AT2)\|(7)_Epithelial_cells / Lung cell shreds - cell class (v4) and cell subclass (v4)	SPPL2B CRLS1 PARL MYDGF SOD2	9.25e-05	200	101	5	b6b59f56497b5a58e2d4eb6a97ada75c93729716
Drug	AC1N4UEG	ACVR1 ACVR1B ACVRL1 SMO	1.54e-06	20	99	4	CID004184747
Drug	SD-208	COL7A1 ACVR1 ACVR1B ACVRL1	2.79e-06	23	99	4	CID010316032
Disease	fibrodysplasia ossificans progressiva (implicated_via_orthology)	ACVR1 ACVRL1	1.00e-05	2	94	2	DOID:13374 (implicated_via_orthology)
Disease	esophagus adenocarcinoma (implicated_via_orthology)	SMO SOD2	1.00e-05	2	94	2	DOID:4914 (implicated_via_orthology)
Disease	pancreatic cancer (is_marker_for)	NTRK1 ACVR1 ACVR1B SMO SOD2	1.83e-05	101	94	5	DOID:1793 (is_marker_for)
Disease	eye movement measurement	CAPN13 CDH22	2.78e-04	8	94	2	EFO_0007699
Disease	tryptase beta-2 measurement	PRSS29P TPSG1	3.56e-04	9	94	2	EFO_0008306
Disease	Focal segmental glomerulosclerosis	MYO1E CD2AP	4.44e-04	10	94	2	cv:C0017668
Disease	Inherited focal segmental glomerulosclerosis	MYO1E CD2AP	4.44e-04	10	94	2	cv:CN327126
Disease	Hereditary Nephrotic Syndromes, Autosomal Dominant	MYO1E CD2AP	5.42e-04	11	94	2	cv:CN043612
Disease	Leigh disease (implicated_via_orthology)	PARL SOD2	6.49e-04	12	94	2	DOID:3652 (implicated_via_orthology)
Disease	puberty onset measurement	MCHR2 FRS3 BIRC6 HERC2	6.97e-04	125	94	4	EFO_0005677
Disease	Connective Tissue Diseases	ACVR1 PKD1	7.65e-04	13	94	2	C0009782
Disease	Familial idiopathic steroid-resistant nephrotic syndrome	MYO1E CD2AP	7.65e-04	13	94	2	cv:C4273714
Disease	Leber hereditary optic neuropathy (is_implicated_in)	PARL SOD2	8.91e-04	14	94	2	DOID:705 (is_implicated_in)
Disease	cataract	CPAMD8 PLB1 HERC2 DNMBP	1.09e-03	141	94	4	MONDO_0005129
Disease	central nervous system disease (implicated_via_orthology)	GRIA3 GRIA4	1.17e-03	16	94	2	DOID:331 (implicated_via_orthology)
Disease	autism spectrum disorder (implicated_via_orthology)	SCAMP4 LAMC3 SHANK3 SHANK2	1.44e-03	152	94	4	DOID:0060041 (implicated_via_orthology)
Disease	mucocutaneous lymph node syndrome	ENPP6 CDH22 SHANK2	1.86e-03	76	94	3	EFO_0004246
Disease	Manic	NTRK1 SHANK3 SHANK2	2.00e-03	78	94	3	C0338831
Disease	Lewy Body Disease	NTRK1 SOD2	2.23e-03	22	94	2	C0752347
Disease	primary open angle glaucoma (is_implicated_in)	ACVR1 SOD2	2.43e-03	23	94	2	DOID:1070 (is_implicated_in)
Disease	myeloid white cell count	SLC25A24 MYO1E NTRK1 PIEZO1 BCL2A1 PSTPIP1 ACVRL1 PKD1 VAV2	3.02e-03	937	94	9	EFO_0007988

Protein segments in the cluster

Peptide	Gene	Start	Entry
DFNRGDISWGGAWAQ	BIRC6	2391	Q9NR09
GRFGEVWRGRWRGGD	ACVR1B	216	P36896
AARWDFDLLNGQGGW	ADGRA3	701	Q8IWK6
AGFGPDWRVRVWTGG	AFDN-DT	76	Q9Y6Z5
VFWDLGRNGGRGGWS	ADGRG2	571	Q8IZP9
KGRYGEVWRGSWQGE	ACVR1	216	Q04771
GEWIRQNGGWENGFV	BCL2A1	131	Q16548
GRYGEVWRGLWHGES	ACVRL1	211	P37023
AGWLQGRSCWGARGF	DNMBP	101	Q6XZF7
GWGEAEWRGRWSDGS	CAPN13	276	Q6MZZ7
AGWWRGELNGKEGVF	CD2AP	306	Q9Y5K6
LDWRMGWGGGAAEAR	CCM2L	201	Q9NUG4
SWERRQAGSGGGGSW	CCM2L	266	Q9NUG4
TGAWLGLYRGGIAWE	CYB561	31	P49447
GWFRGVDRSLLLQGW	CDK5R2	211	Q13319
GGFRWGRFAGWGRAL	RASAL3	36	Q86YV0
DAGVVGGQSWNRAWE	IQCN	876	Q9H0B3
GGQSWNRAWEPARGA	IQCN	881	Q9H0B3
WNPSLGVSERRGGDW	CDKN2A-DT	46	Q9UH64
KAGAGWGWRARRAGT	CFAP99	621	D6REC4
WWTVERNGQRGFVPG	PSTPIP1	396	O43586
SLGAQAGWRTAGWEA	FAM201A	51	Q5SY85
RRGQLGWHSWAAGPG	NTRK1	6	P04629
WGPQRLNSGGRWDSE	NAXE	36	Q8NCW5
GAGGNINARDAFWWT	GPANK1	131	O95872
GRWGGHRLGNNTAAW	MGAM2	1471	Q2M2H8
FISDGSVNGWGWRFT	HERC2	3691	O95714
GRRGSTRGWAFSSWQ	HEMK1	16	Q9Y5R4
SGIRGAQAGWGVWGP	LAT	116	O43561
SGGPHWDWDVTRAGR	ATRN	26	O75882
WTYRGEWLGGLKGRS	JPH4	81	Q96JJ6
RSLSGRIVGGVWWFF	GRIA3	626	P42263
RSLSGRIVGGVWWFF	GRIA4	616	P48058
AARGTWWNRPGGTSG	FDX2	21	Q6P4F2
GWHDVAGWLGRGGSM	PFKL	451	P17858
WGSGGRLGVRFGEWS	KRT78	56	Q8N1N4
QGGNIRGPWARGWKS	RSKR	26	Q96LW2
GRGPAIGGQWRGFWE	LONP1	56	P36776
IGGQWRGFWEASSRG	LONP1	61	P36776
RGWTAAHWAAAGGRL	ANKRD65	176	E5RJM6
EWAGRGDLGGFKRRW	KLLN	36	B2CW77
GSGSAREGWLFKWTN	OSBP	86	P22059
AGGVESARGRWPWQA	PRSS41	56	Q7RTY9
WFGGRQITAQAWDGT	HTATSF1	336	O43719
GATAAWWGLSREPRG	POM121	61	Q96HA1
HQWARGGEWVFGGPL	MCHR2	91	Q969V1
GLGSRAWRVSWEGAA	PAX1	6	P15863
VGWGSTVGRWARVEG	GMPPA	341	Q96IJ6
WTYRGGQGGRWTRRA	LINC00482	116	Q8N8I6
AIRSTWGRVGGWARG	B3GNT4	136	Q9C0J1
FVNQSWARGQGSGWL	CD1C	36	P29017
TYENVTGGLWRGAGW	FRS3	286	O43559
GFSTGWGSMGEFRIW	CPAMD8	1076	Q8IZJ3
KNSWGTGWGENGYFR	CTSC	426	P53634
KSGVGRNWGWASAGS	MAN1A2	316	O60476
GRKWSLWEGGVRGVG	ARSB	316	P15848
WVGVTGATAYRLAWG	COL7A1	796	Q02388
GAGRVKRGWVWNQFF	CDH22	56	Q9UJ99
RWVGRCGRQLSGGWV	ENGASE	551	Q8NFI3
NSTGRREGWQRGWHG	ENPP6	341	Q6UWR7
WWIGGGSGTNFGLAF	SCAMP4	61	Q969E2
AWSQCGGGGLRAWSQ	CPOX	26	P36551
VARGSWGALRGAAWA	CRLS1	6	Q9UJA2
GRGTLLAFAAWTAGW	DIPK1C	21	Q0P6D2
GDWCGSQRSGWGRMY	MORN3	116	Q6PF18
WTAWRDRGPALAGSG	PKD1	1666	P98161
WGCGQAWGASVGGRS	PARL	11	Q9H300
GSGRARWARGGQAGW	RUSC2	1256	Q8N2Y8
GVAGGWRRFERLWAG	MRPL46	11	Q9H2W6
GIRCWVTGWGYTREG	TPSG1	156	Q9NRR2
CALYGLWDGGRGWSR	TDRD6	376	O60522
LWDGGRGWSRSQVGD	TDRD6	381	O60522
RGSWRLVGVVSWGYG	PRSS29P	271	A6NIE9
RRSAATVAAWGGWGG	TRPC4AP	16	Q8TEL6
GDEGWWAGQVQRRLG	MAP3K21	76	Q5TCX8
AGVTSWGLGCGRGWR	OVCH2	256	Q7RTZ1
WRASGWDGMGFFSRR	SCOC	11	Q9UIL1
SWRGLSWSIGGDGNL	PLB1	1121	Q6P1J6
GGFWEGSARGHIGWF	SHANK2	561	Q9UPX8
WGWGDGSSHGSQAER	APOBR	101	Q0VD83
GAGAARGRASWCWAL	CLN5	16	O75503
GTGISDGDFWIGLWR	CHODL	91	Q9H9P2
DGDFWIGLWRNGDGQ	CHODL	96	Q9H9P2
WWRHLVAGGGAGAVS	SLC25A25	186	Q6KCM7
DSRNGQLGGQGWLWG	WNT8B	116	Q93098
GETFVQSGRWDGGWR	nan	66	Q9BRP9
MGGFGSRFWQEGVWD	nan	1	Q8NFD4
RLWAWRGGGESPNSR	TVP23C	246	Q96ET8
GGFWEGTVKGRTGWF	SHANK3	506	Q9BYB0
GVFWRRANEQGAFWG	SLC5A10	461	A0PJK1
GWASSRFGWFGLDAE	TMEM144	106	Q7Z5S9
GGGRRAWQTLWFQSE	STPG3	136	Q8N7X2
GQQGWWRGEIYGRVG	VAV1	816	P15498
WRRELGVFWTGSGFA	SPPL2B	491	Q8TCT7
RAWRGAWRGGGAADL	nan	6	A6NDN8
LGVGSWLLFNNWTGG	KRT10-AS1	101	Q8N816
TAASVGVQGSGWGWL	SOD2	136	P04179
AGAWGAGDSCRQGAW	SMO	716	Q99835
AGAGWWVGAAYASLR	TRIM14	331	Q14142
RQSTSQPWRGGAGAW	SNAPC4	576	Q5SXM2
REQGAGATGFLEWWV	PIEZO1	2391	Q92508
YSRIGGDQGWWKGET	VAV2	846	P52735
GAAQWFGVSGDWEGQ	RHBDF2	121	Q6PJF5
SGGGWLSNSGAVDWN	ZNF106	181	Q9H2Y7
SGQWWRQLLAGGIAG	SLC25A24	191	Q6NUK1
TWDNSPLRIGGGWGN	TNRC6A	1746	Q8NDV7
AGAVWAVEGRGGRLW	RNF39	331	Q9H2S5
QGAEGWWARSVGGSE	LAMC3	506	Q9Y6N6
GGWNGVGASLWAALL	MYDGF	6	Q969H8
SGWWTGRLRGKQGLF	MYO1E	1086	Q12965