Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	NAD transmembrane transporter activity	SLC25A17 SLC25A51 SLC25A52	1.46e-05	5	229	3	GO:0051724
GeneOntologyMolecularFunction	ATP-dependent activity	ABCA1 ATP8B4 MYO1A ACSM1 KIF4A CHD2 AK9 DDX6 KIF14 DDX60L ABCC1 DDX12P DDX60 WRN ABCE1 DNAH17 MACF1 XRCC6 HELLS	9.10e-05	614	229	19	GO:0140657
GeneOntologyMolecularFunction	alpha-1A adrenergic receptor binding	ARRB1 ARRB2	1.31e-04	2	229	2	GO:0031691
GeneOntologyMolecularFunction	angiotensin receptor binding	EDNRB ARRB1 ARRB2	1.68e-04	10	229	3	GO:0031701
GeneOntologyMolecularFunction	adenine nucleotide transmembrane transporter activity	SLC25A17 SLC25A4 SLC25A51 SLC25A52	2.07e-04	26	229	4	GO:0000295
GeneOntologyMolecularFunction	purine nucleotide transmembrane transporter activity	SLC25A17 SLC25A4 SLC25A51 SLC25A52	3.19e-04	29	229	4	GO:0015216
GeneOntologyMolecularFunction	inositol 1,4,5-trisphosphate-gated calcium channel activity	ITPR2 ITPR3	3.90e-04	3	229	2	GO:0005220
GeneOntologyMolecularFunction	follicle-stimulating hormone receptor binding	ARRB1 ARRB2	3.90e-04	3	229	2	GO:0031762
GeneOntologyMolecularFunction	alpha-1B adrenergic receptor binding	ARRB1 ARRB2	3.90e-04	3	229	2	GO:0031692
GeneOntologyMolecularFunction	helicase activity	CHD2 DDX6 DDX60L DDX12P DDX60 WRN XRCC6 HELLS	4.88e-04	158	229	8	GO:0004386
GeneOntologyMolecularFunction	gated channel activity	PIEZO1 BEST3 ITPR2 ITPR3 PTK2B CLCN2 CLCN7 SCN7A SCNN1B TRPM8 PIEZO2 P2RX5	5.02e-04	334	229	12	GO:0022836
GeneOntologyMolecularFunction	nucleotide transmembrane transporter activity	SLC25A17 SLC25A4 SLC25A51 SLC25A52	5.31e-04	33	229	4	GO:0015215
GeneOntologyMolecularFunction	kinase activity	CDK17 CDKL3 AK9 PXK MAP3K5 NRP1 PHKA1 PTK2B MYLK4 FAM20B PIP5K1A ROCK2 MINK1 PDPK2P STK16 LIMK1 EPHA2 PRKCD EIF2AK4 EIF2AK2	5.35e-04	764	229	20	GO:0016301
GeneOntologyMolecularFunction	phosphotransferase activity, alcohol group as acceptor	CDK17 CDKL3 PXK MAP3K5 NRP1 PHKA1 PTK2B MYLK4 FAM20B PIP5K1A ROCK2 MINK1 PDPK2P STK16 LIMK1 EPHA2 PRKCD EIF2AK4 EIF2AK2	5.56e-04	709	229	19	GO:0016773
GeneOntologyMolecularFunction	protein kinase activity	CDK17 CDKL3 PXK MAP3K5 NRP1 PHKA1 PTK2B MYLK4 ROCK2 MINK1 PDPK2P STK16 LIMK1 EPHA2 PRKCD EIF2AK4 EIF2AK2	5.87e-04	600	229	17	GO:0004672
GeneOntologyMolecularFunction	ATP hydrolysis activity	ABCA1 ATP8B4 CHD2 AK9 DDX6 KIF14 DDX60L ABCC1 DDX12P DDX60 WRN ABCE1 MACF1 XRCC6	6.01e-04	441	229	14	GO:0016887
GeneOntologyMolecularFunction	protein serine/threonine kinase activity	CDK17 CDKL3 MAP3K5 PHKA1 PTK2B MYLK4 ROCK2 MINK1 PDPK2P STK16 LIMK1 PRKCD EIF2AK4 EIF2AK2	6.71e-04	446	229	14	GO:0004674
GeneOntologyMolecularFunction	hedgehog family protein binding	PTCH1 HHIP	7.74e-04	4	229	2	GO:0097108
GeneOntologyMolecularFunction	organophosphate ester transmembrane transporter activity	SLC25A17 SLC25A4 SLC25A51 SLC25A52	1.01e-03	39	229	4	GO:0015605
GeneOntologyMolecularFunction	ubiquitin-like protein peptidase activity	USP45 USP25 USP9Y PAN2 USP24 USP14 COPS4	1.04e-03	137	229	7	GO:0019783
GeneOntologyMolecularFunction	adenine transmembrane transporter activity	SLC25A4 SLC43A3	1.28e-03	5	229	2	GO:0015207
GeneOntologyBiologicalProcess	NAD transmembrane transport	SLC25A17 SLC25A51 SLC25A52	1.23e-05	5	223	3	GO:0035352
GeneOntologyBiologicalProcess	cell morphogenesis	RIPOR2 CDKL3 DCC PTCH1 ADAM8 ITGB3 NRP1 PTK2B GRXCR2 DST STXBP1 NBEAL2 SEC24B ROCK2 MINK1 L1CAM NR4A3 XK SRGAP2 CFAP43 JMJD1C BTBD3 POSTN LIF LIMK1 EPHA2 MACF1 EIF2AK4 TRAK2 MYO16	1.46e-05	1194	223	30	GO:0000902
GeneOntologyBiologicalProcess	nucleotide transport	SLC25A17 ABCC1 SLC25A4 SLC25A51 EPG5 SLC25A52	1.59e-05	50	223	6	GO:0006862
GeneOntologyBiologicalProcess	cell-substrate junction assembly	ITGB3 NRP1 PTK2B DST PIP5K1A ROCK2 PDPK2P MACF1	2.29e-05	108	223	8	GO:0007044
GeneOntologyBiologicalProcess	NAD transport	SLC25A17 SLC25A51 SLC25A52	2.43e-05	6	223	3	GO:0043132
GeneOntologyBiologicalProcess	cell-substrate junction organization	ITGB3 NRP1 PTK2B DST PIP5K1A ROCK2 PDPK2P MACF1	3.61e-05	115	223	8	GO:0150115
GeneOntologyBiologicalProcess	negative regulation of apoptotic process	NUGGC PRAMEF2 ADAM8 ADAR BIRC6 ITGB3 NRP1 GHRH PTK2B SERPINB9 STXBP1 ALMS1 SCG2 MITF KIF14 NOS1 SLC25A4 NR4A3 UFL1 PDPK2P EDNRB HHIP ARRB1 ARRB2 PRKCD CCAR2 EIF2AK2 HELLS	3.89e-05	1133	223	28	GO:0043066
GeneOntologyBiologicalProcess	chemotaxis	RIPOR2 ADAM8 ITGB3 NRP1 PTK2B SCG2 PIP5K1A CCR4 DOCK2 ABCC1 L1CAM CCRL2 EDNRB USP14 ARRB2 EPHA2 PRKCD	5.07e-05	517	223	17	GO:0006935
GeneOntologyBiologicalProcess	taxis	RIPOR2 ADAM8 ITGB3 NRP1 PTK2B SCG2 PIP5K1A CCR4 DOCK2 ABCC1 L1CAM CCRL2 EDNRB USP14 ARRB2 EPHA2 PRKCD	5.32e-05	519	223	17	GO:0042330
GeneOntologyBiologicalProcess	response to abiotic stimulus	RIPOR2 PIEZO1 PTCH1 RRM1 ADAM8 ITGB3 HP1BP3 ITPR2 PTK2B KARS1 CLCN7 SCN7A SCNN1B TRPM8 NOS1 ROCK2 WRN COPS3 PDPK2P POSTN LIF EYS PIEZO2 ARRB1 ARRB2 P2RX5 RRH PRKCD CCAR2 EIF2AK4 XRCC6	6.76e-05	1361	223	31	GO:0009628
GeneOntologyBiologicalProcess	purine-containing compound transmembrane transport	SLC25A17 SLC25A4 SLC43A3 SLC25A51 SLC25A52	6.83e-05	40	223	5	GO:0072530
GeneOntologyBiologicalProcess	negative regulation of programmed cell death	NUGGC PRAMEF2 ADAM8 ADAR BIRC6 ITGB3 NRP1 GHRH PTK2B SERPINB9 STXBP1 ALMS1 SCG2 MITF KIF14 NOS1 SLC25A4 NR4A3 UFL1 PDPK2P EDNRB HHIP ARRB1 ARRB2 PRKCD CCAR2 EIF2AK2 HELLS	6.90e-05	1171	223	28	GO:0043069
GeneOntologyBiologicalProcess	organophosphate ester transport	ABCA1 ATP8B4 SLC25A17 ABCC1 SLC25A4 SLC25A51 EPG5 PRKCD SLC25A52	6.94e-05	162	223	9	GO:0015748
GeneOntologyBiologicalProcess	maintenance of protein complex location	EPG5 TMEM232	1.16e-04	2	223	2	GO:0098544
GeneOntologyBiologicalProcess	positive regulation of opioid receptor signaling pathway	ITGB3 ARRB2	1.16e-04	2	223	2	GO:2000476
GeneOntologyBiologicalProcess	mitochondrial NAD transmembrane transport	SLC25A51 SLC25A52	1.16e-04	2	223	2	GO:1990549
GeneOntologyBiologicalProcess	plasma membrane bounded cell projection assembly	RIPOR2 MYO1A FRMD7 ODAD4 RABGAP1 BBS9 NRP1 ALMS1 PIP5K1A CFAP47 CNTRL MINK1 SRGAP2 CFAP43 EPHA2 DNAH17 PRKCD CFAP74 CFAP69	1.31e-04	670	223	19	GO:0120031
GeneOntologyBiologicalProcess	regulation of muscle cell apoptotic process	MAP3K5 GHRH PTK2B SLC25A4 NR4A3 PDPK2P ARRB1 ARRB2	1.52e-04	141	223	8	GO:0010660
GeneOntologyBiologicalProcess	calcium-mediated signaling	ITPR2 ITPR3 ALMS1 TRPM8 CCR4 NOS1 ANK2 L1CAM CCRL2 EDNRB P2RX5	1.59e-04	266	223	11	GO:0019722
GeneOntologyBiologicalProcess	cell chemotaxis	RIPOR2 ADAM8 NRP1 PTK2B SCG2 PIP5K1A CCR4 ABCC1 CCRL2 EDNRB ARRB2 EPHA2 PRKCD	1.72e-04	363	223	13	GO:0060326
GeneOntologyBiologicalProcess	cell projection assembly	RIPOR2 MYO1A FRMD7 ODAD4 RABGAP1 BBS9 NRP1 ALMS1 PIP5K1A CFAP47 CNTRL MINK1 SRGAP2 CFAP43 EPHA2 DNAH17 PRKCD CFAP74 CFAP69	1.74e-04	685	223	19	GO:0030031
GeneOntologyBiologicalProcess	cell-matrix adhesion	ADAM8 ITGB3 NRP1 PTK2B PIP5K1A ROCK2 MINK1 L1CAM PDPK2P POSTN MACF1	1.81e-04	270	223	11	GO:0007160
GeneOntologyBiologicalProcess	axoneme assembly	ODAD4 CFAP47 CNTRL CFAP43 DNAH17 CFAP74 CFAP69	1.84e-04	109	223	7	GO:0035082
GeneOntologyBiologicalProcess	muscle cell apoptotic process	MAP3K5 GHRH PTK2B SLC25A4 NR4A3 PDPK2P ARRB1 ARRB2	2.32e-04	150	223	8	GO:0010657
GeneOntologyBiologicalProcess	negative regulation of neuron apoptotic process	ADAM8 NRP1 PTK2B STXBP1 KIF14 NOS1 NR4A3 PDPK2P ARRB1 ARRB2	2.60e-04	236	223	10	GO:0043524
GeneOntologyCellularComponent	perinuclear region of cytoplasm	ABCA1 PDE9A PTCH1 DDX6 ITPR3 PTK2B DST STXBP1 SYNJ1 RAB40AL NOS1 ANK2 CNTRL PPP1R13B COPS3 RAB40A EPG5 STK16 LIMK1 UNC45B LNPEP PRKCD EIF2AK2 MYO16	8.57e-05	934	227	24	GO:0048471
GeneOntologyCellularComponent	alpha9-beta1 integrin-ADAM8 complex	ADAM8 ITGB3	1.17e-04	2	227	2	GO:0071133
GeneOntologyCellularComponent	axonal growth cone	DCC PTCH1 L1CAM LIMK1 TRAK2	1.24e-04	45	227	5	GO:0044295
GeneOntologyCellularComponent	A band	MYOM1 DST ANK2 SMTNL1 UNC45B	2.48e-04	52	227	5	GO:0031672
GeneOntologyCellularComponent	motile cilium	CFAP251 ODAD4 PRAMEF2 DDX6 HAVCR1 CFAP47 CFAP43 TMEM232 DNAH17 CFAP74 CATSPERB CFAP69	5.33e-04	355	227	12	GO:0031514
GeneOntologyCellularComponent	cytoplasmic region	CFAP251 KIF4A ODAD4 DST STXBP1 BSN CNTRL CFAP43 DNAH17 CFAP74 TRAK2 CFAP69	6.03e-04	360	227	12	GO:0099568
GeneOntologyCellularComponent	retromer, cargo-selective complex	VPS26B VPS26A	6.94e-04	4	227	2	GO:0030906
GeneOntologyCellularComponent	plasma membrane bounded cell projection cytoplasm	CFAP251 KIF4A ODAD4 DST BSN CNTRL CFAP43 DNAH17 CFAP74 TRAK2 CFAP69	7.30e-04	317	227	11	GO:0032838
GeneOntologyCellularComponent	proteasome complex	USP25 PSMD1 PSMD6 PSME4 USP14	8.07e-04	67	227	5	GO:0000502
GeneOntologyCellularComponent	cilium	CFAP251 TTC21A ODAD4 PTCH1 PRAMEF2 BBS9 DDX6 HAVCR1 ALMS1 CFAP47 CNTRL CFAP43 TTLL7 HHIP EYS TMEM232 DNAH17 RRH CFAP74 CATSPERB CFAP69	8.23e-04	898	227	21	GO:0005929
HumanPheno	Coiled sperm flagella	CFAP251 TTC21A CFAP47 CFAP43 DNAH17 CFAP74 CFAP69	2.83e-07	32	75	7	HP:0032560
HumanPheno	Short sperm flagella	CFAP251 TTC21A CFAP47 CFAP43 DNAH17 CFAP74 CFAP69	3.55e-07	33	75	7	HP:0032559
HumanPheno	Abnormal sperm tail morphology	CFAP251 TTC21A CFAP47 CFAP43 DNAH17 CFAP74 CFAP69	2.38e-06	43	75	7	HP:0012868
HumanPheno	Abnormal sperm morphology	CFAP251 TTC21A CFAP47 CFAP43 DNAH17 CFAP74 CFAP69	4.39e-05	66	75	7	HP:0012864
HumanPheno	Absent sperm flagella	CFAP251 TTC21A CFAP47 CFAP43 DNAH17	4.56e-05	28	75	5	HP:0032558
HumanPheno	Abnormal germ cell morphology	CFAP251 TTC21A CFAP47 CFAP43 DNAH17 CFAP74 CFAP69	4.85e-05	67	75	7	HP:0012862
HumanPheno	Abnormal male germ cell morphology	CFAP251 TTC21A CFAP47 CFAP43 DNAH17 CFAP74 CFAP69	4.85e-05	67	75	7	HP:0012863
Domain	ARM-type_fold	RIPOR2 PSMD1 ARMH1 USP9Y ITPR2 PSME4 NBEAL2 ASPM CAB39L TARBP1 DOCK2 COPB1 USP24 CWC22 VIRMA RANBP17 UNC45B CFAP69 XPO7	2.35e-08	339	221	19	IPR016024
Domain	ARM-like	RIPOR2 PSMD1 ARMH1 USP9Y PSME4 NBEAL2 ASPM CAB39L TARBP1 DOCK2 COPB1 RANBP17 UNC45B CFAP69 XPO7	8.26e-07	270	221	15	IPR011989
Domain	-	SLC25A30 SLC25A17 SLC25A4 SLC25A14 SLC25A51 SLC25A44 SLC25A52	2.87e-06	53	221	7	1.50.40.10
Domain	Mito_carr	SLC25A30 SLC25A17 SLC25A4 SLC25A14 SLC25A51 SLC25A44 SLC25A52	2.87e-06	53	221	7	PF00153
Domain	SOLCAR	SLC25A30 SLC25A17 SLC25A4 SLC25A14 SLC25A51 SLC25A44 SLC25A52	2.87e-06	53	221	7	PS50920
Domain	Mitochondrial_sb/sol_carrier	SLC25A30 SLC25A17 SLC25A4 SLC25A14 SLC25A51 SLC25A44 SLC25A52	2.87e-06	53	221	7	IPR018108
Domain	Mt_carrier_dom	SLC25A30 SLC25A17 SLC25A4 SLC25A14 SLC25A51 SLC25A44 SLC25A52	2.87e-06	53	221	7	IPR023395
Domain	Mit_uncoupling	SLC25A30 SLC25A17 SLC25A4 SLC25A14	8.77e-06	12	221	4	IPR002030
Domain	-	DST DSP MACF1	3.18e-05	6	221	3	3.90.1290.10
Domain	Plectin	DST DSP MACF1	5.52e-05	7	221	3	PF00681
Domain	Plectin_repeat	DST DSP MACF1	5.52e-05	7	221	3	IPR001101
Domain	PLEC	DST DSP MACF1	5.52e-05	7	221	3	SM00250
Domain	PIEZO	PIEZO1 PIEZO2	1.39e-04	2	221	2	PF15917
Domain	Piezo	PIEZO1 PIEZO2	1.39e-04	2	221	2	IPR027272
Domain	Piezo_RRas_bdg	PIEZO1 PIEZO2	1.39e-04	2	221	2	PF12166
Domain	Piezo_RRas-bd_dom	PIEZO1 PIEZO2	1.39e-04	2	221	2	IPR031334
Domain	Piezo_dom	PIEZO1 PIEZO2	1.39e-04	2	221	2	IPR031805
Domain	UCH	USP45 USP25 USP9Y PAN2 USP24 USP14	1.93e-04	71	221	6	PF00443
Domain	USP_3	USP45 USP25 USP9Y PAN2 USP24 USP14	2.09e-04	72	221	6	PS50235
Domain	USP_dom	USP45 USP25 USP9Y PAN2 USP24 USP14	2.09e-04	72	221	6	IPR028889
Domain	Peptidase_C19_UCH	USP45 USP25 USP9Y PAN2 USP24 USP14	2.09e-04	72	221	6	IPR001394
Domain	Aden_trnslctor	SLC25A17 SLC25A4 SLC25A14 SLC25A44	3.13e-04	28	221	4	IPR002113
Domain	-	RIPOR2 PSMD1 ARMH1 PSME4 ASPM CAB39L COPB1 RANBP17 UNC45B CFAP69	3.24e-04	222	221	10	1.25.10.10
Domain	Vps26-related	VPS26B VPS26A	4.15e-04	3	221	2	IPR028934
Domain	MITF_TFEB_C_3_N	MITF TFE3	4.15e-04	3	221	2	PF15951
Domain	Vps26	VPS26B VPS26A	4.15e-04	3	221	2	PF03643
Domain	InsP3_rcpt-bd	ITPR2 ITPR3	4.15e-04	3	221	2	IPR000493
Domain	Elf-1_N	ELF1 ELF2	4.15e-04	3	221	2	PF12310
Domain	MiT/TFE_N	MITF TFE3	4.15e-04	3	221	2	IPR031867
Domain	TF_Elf_N	ELF1 ELF2	4.15e-04	3	221	2	IPR022084
Domain	TPR-like_helical_dom	TTC21A ODAD4 PSMD6 COPS3 ZFC3H1 RMDN3 UNC45B CAPN7 COPS4 NUB1	4.74e-04	233	221	10	IPR011990
Domain	Mit_carrier	SLC25A17 SLC25A4 SLC25A14 SLC25A44	5.29e-04	32	221	4	IPR002067
Domain	IQ_motif_EF-hand-BS	MYO1A SCN7A ASPM IQSEC3 IQCH MYO16	6.98e-04	90	221	6	IPR000048
Domain	Kinase-like_dom	CDK17 CDKL3 PXK MAP3K5 PTK2B DST MYLK4 ROCK2 MINK1 STK16 LIMK1 EPHA2 MACF1 PRKCD EIF2AK4 EIF2AK2	7.58e-04	542	221	16	IPR011009
Domain	Disintegrin_CS	ADAM8 ADAM30 ADAM12	8.17e-04	16	221	3	IPR018358
Domain	PINT	PSMD6 COPS3 COPS4	8.17e-04	16	221	3	SM00088
Domain	Arrestin_N	ARRB1 ARRB2	8.23e-04	4	221	2	IPR014753
Domain	Arrestin_CS	ARRB1 ARRB2	8.23e-04	4	221	2	IPR017864
Domain	ARRESTINS	ARRB1 ARRB2	8.23e-04	4	221	2	PS00295
Domain	DUF3371	MITF TFE3	8.23e-04	4	221	2	PF11851
Domain	Arrestin	ARRB1 ARRB2	8.23e-04	4	221	2	IPR000698
Domain	-	ARRB1 ARRB2	8.23e-04	4	221	2	2.60.40.840
Domain	MiT/TFE_C	MITF TFE3	8.23e-04	4	221	2	IPR021802
Domain	PCI_dom	PSMD6 COPS3 COPS4	9.83e-04	17	221	3	IPR000717
Domain	PCI	PSMD6 COPS3 COPS4	9.83e-04	17	221	3	PF01399
Domain	USP_CS	USP45 USP25 USP9Y USP24 USP14	1.10e-03	66	221	5	IPR018200
Domain	ADAM_CR	ADAM8 ADAM30 ADAM12	1.17e-03	18	221	3	PF08516
Domain	USP_1	USP45 USP25 USP9Y USP24 USP14	1.44e-03	70	221	5	PS00972
Domain	USP_2	USP45 USP25 USP9Y USP24 USP14	1.53e-03	71	221	5	PS00973
Domain	Ubiquitin-rel_dom	FRMD7 PTK2B PTPN3 TLN2 USP24 PPP1R13B USP14 NUB1	1.60e-03	184	221	8	IPR029071
Domain	-	ADAM8 ADAM30 ADAM12	1.61e-03	20	221	3	4.10.70.10
Domain	Helicase_C	CHD2 DDX6 DDX60L DDX60 WRN HELLS	1.72e-03	107	221	6	PF00271
Domain	HELICc	CHD2 DDX6 DDX60L DDX60 WRN HELLS	1.72e-03	107	221	6	SM00490
Domain	Helicase_C	CHD2 DDX6 DDX60L DDX60 WRN HELLS	1.80e-03	108	221	6	IPR001650
Domain	Disintegrin	ADAM8 ADAM30 ADAM12	1.86e-03	21	221	3	PF00200
Domain	DISIN	ADAM8 ADAM30 ADAM12	1.86e-03	21	221	3	SM00050
Domain	HELICASE_CTER	CHD2 DDX6 DDX60L DDX60 WRN HELLS	1.89e-03	109	221	6	PS51194
Domain	HELICASE_ATP_BIND_1	CHD2 DDX6 DDX60L DDX60 WRN HELLS	1.89e-03	109	221	6	PS51192
Domain	DEXDc	CHD2 DDX6 DDX60L DDX60 WRN HELLS	1.89e-03	109	221	6	SM00487
Domain	Protein_kinase_ATP_BS	CDK17 CDKL3 MAP3K5 PTK2B MYLK4 ROCK2 MINK1 LIMK1 EPHA2 PRKCD EIF2AK4 EIF2AK2	1.93e-03	379	221	12	IPR017441
Domain	Helicase_ATP-bd	CHD2 DDX6 DDX60L DDX60 WRN HELLS	1.98e-03	110	221	6	IPR014001
Domain	Pkinase	CDK17 CDKL3 PXK MAP3K5 MYLK4 ROCK2 MINK1 STK16 LIMK1 PRKCD EIF2AK4 EIF2AK2	2.01e-03	381	221	12	PF00069
Domain	Sec23/24_helical_dom	SEC24A SEC24B	2.03e-03	6	221	2	IPR006900
Domain	RIH_assoc-dom	ITPR2 ITPR3	2.03e-03	6	221	2	IPR013662
Domain	Sec23_24_beta_S	SEC24A SEC24B	2.03e-03	6	221	2	IPR012990
Domain	zf-Sec23_Sec24	SEC24A SEC24B	2.03e-03	6	221	2	PF04810
Domain	Sec23_trunk	SEC24A SEC24B	2.03e-03	6	221	2	PF04811
Domain	Sec23_helical	SEC24A SEC24B	2.03e-03	6	221	2	PF04815
Domain	GAR	DST MACF1	2.03e-03	6	221	2	PS51460
Domain	Ins145_P3_rec	ITPR2 ITPR3	2.03e-03	6	221	2	PF08709
Domain	GAS2	DST MACF1	2.03e-03	6	221	2	PF02187
Domain	RIH_assoc	ITPR2 ITPR3	2.03e-03	6	221	2	PF08454
Domain	RIH_dom	ITPR2 ITPR3	2.03e-03	6	221	2	IPR000699
Domain	Ins145_P3_rcpt	ITPR2 ITPR3	2.03e-03	6	221	2	IPR014821
Domain	Ryanodine_recept-rel	ITPR2 ITPR3	2.03e-03	6	221	2	IPR015925
Domain	Sec23_BS	SEC24A SEC24B	2.03e-03	6	221	2	PF08033
Domain	-	ITPR2 ITPR3	2.03e-03	6	221	2	1.25.10.30
Domain	-	DST MACF1	2.03e-03	6	221	2	3.30.920.20
Domain	RYDR_ITPR	ITPR2 ITPR3	2.03e-03	6	221	2	PF01365
Domain	Sec23/24_trunk_dom	SEC24A SEC24B	2.03e-03	6	221	2	IPR006896
Domain	Znf_Sec23_Sec24	SEC24A SEC24B	2.03e-03	6	221	2	IPR006895
Domain	GAS_dom	DST MACF1	2.03e-03	6	221	2	IPR003108
Domain	GAS2	DST MACF1	2.03e-03	6	221	2	SM00243
Domain	FERM_M	FRMD7 PTK2B PTPN3 TLN2	2.11e-03	46	221	4	PF00373
Domain	Prot_kinase_dom	CDK17 CDKL3 PXK MAP3K5 PTK2B MYLK4 ROCK2 MINK1 STK16 LIMK1 EPHA2 PRKCD EIF2AK4 EIF2AK2	2.13e-03	489	221	14	IPR000719
Domain	PROTEIN_KINASE_DOM	CDK17 CDKL3 PXK MAP3K5 PTK2B MYLK4 ROCK2 MINK1 STK16 LIMK1 EPHA2 PRKCD EIF2AK4 EIF2AK2	2.30e-03	493	221	14	PS50011
Domain	-	FRMD7 PTK2B PTPN3 TLN2	2.66e-03	49	221	4	1.20.80.10
Domain	FERM_central	FRMD7 PTK2B PTPN3 TLN2	2.66e-03	49	221	4	IPR019748
Domain	FERM_domain	FRMD7 PTK2B PTPN3 TLN2	2.66e-03	49	221	4	IPR000299
Domain	IQ	MYO1A SCN7A ASPM IQCH MYO16	2.74e-03	81	221	5	SM00015
Domain	FERM_CS	FRMD7 PTPN3 TLN2	2.75e-03	24	221	3	IPR019747
Domain	-	ARRB1 ARRB2	2.81e-03	7	221	2	2.60.40.640
Domain	FERM/acyl-CoA-bd_prot_3-hlx	FRMD7 PTK2B PTPN3 TLN2	2.87e-03	50	221	4	IPR014352
Domain	FERM_1	FRMD7 PTK2B PTPN3 TLN2	2.87e-03	50	221	4	PS00660
Domain	FERM_2	FRMD7 PTK2B PTPN3 TLN2	2.87e-03	50	221	4	PS00661
Domain	FERM_3	FRMD7 PTK2B PTPN3 TLN2	2.87e-03	50	221	4	PS50057
Domain	Band_41_domain	FRMD7 PTK2B PTPN3 TLN2	2.87e-03	50	221	4	IPR019749
Domain	B41	FRMD7 PTK2B PTPN3 TLN2	2.87e-03	50	221	4	SM00295
Domain	fn3	MYOM1 DCC UMODL1 SDK2 L1CAM EPHA2 ANKFN1	3.21e-03	162	221	7	PF00041
Domain	PROTEIN_KINASE_ATP	CDK17 CDKL3 MAP3K5 PTK2B MYLK4 ROCK2 MINK1 STK16 LIMK1 EPHA2 PRKCD EIF2AK4 EIF2AK2	3.34e-03	459	221	13	PS00107
Pubmed	Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.	PDCD2 RPS10 KIF4A PSMD1 CHD2 RRM1 ADAR BIRC6 DDX6 KARS1 DST PSME4 GLYR1 SEC24B ASPM AP1M1 DDX60L COPB1 DSP COPS3 VPS26A DIS3 USP14 ARRB2 ABCE1 CSTF1 MACF1 PRKCD CCAR2 EIF2AK2 XRCC6	2.38e-09	1353	232	31	29467282
Pubmed	Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.	RPS10 KIF4A PSMD1 CHD2 BIRC6 HP1BP3 ITPR3 KARS1 DST GLYR1 KIF14 COPB1 DSP USP24 VIRMA DIS3 ABCE1 MACF1 CCAR2 XRCC6 XPO7	3.69e-09	653	232	21	22586326
Pubmed	Defining the membrane proteome of NK cells.	RPS10 KIF4A PSMD1 TUBGCP4 ADAR BIRC6 CLCC1 DDX6 ITPR2 ITPR3 SERPINB9 CLCN7 NBEAL2 DHCR24 KIF14 AP1M1 ZDHHC13 SLC25A17 DOCK2 ABCC1 COPB1 CNTRL DIS3 ABCE1 LNPEP EIF2AK2 XRCC6	2.33e-08	1168	232	27	19946888
Pubmed	The mitochondrial transporter family SLC25: identification, properties and physiopathology.	SLC25A30 SLC25A17 SLC25A4 SLC25A14 SLC25A51 SLC25A44 SLC25A52	6.37e-08	53	232	7	23266187
Pubmed	Mapping the MOB proteins' proximity network reveals a unique interaction between human MOB3C and the RNase P complex.	LRRC49 KIF4A PSMD1 PSMD6 KARS1 COPB1 DSP MINK1 UFL1 COPS3 CWC22 EPHA2 COPS4 CCAR2 XRCC6	9.25e-08	399	232	15	37536630
Pubmed	Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.	TUBGCP4 ITGB3 HP1BP3 NRP1 DST PSME4 PIP5K1A AP1M1 PZP SLC25A17 SLC25A4 MINK1 CWC22 JMJD1C DIS3 ABCE1 EIF2AK4 TNFAIP2 HELLS	9.37e-08	650	232	19	38777146
Pubmed	KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.	CDK17 TTC21A LRRC49 RPS10 DDX6 HP1BP3 ITPR2 PSMD6 PTK2B KARS1 DST STXBP1 SYNJ1 TLN2 BSN NOS1 ROCK2 IQSEC3 ANK2 SLC25A4 COPB1 DSP MINK1 L1CAM SRGAP2 COPS3 VIRMA MACF1 CEP170B	1.14e-07	1431	232	29	37142655
Pubmed	Large-scale mapping of human protein-protein interactions by mass spectrometry.	CDK17 PCDHB5 RPS10 KIF4A PSMD1 ODAD4 DDX6 PSMD6 PTPN3 ASPM CAB39L ROCK2 DSP UFL1 SRGAP2 COPS3 JMJD1C TFE3 STK16 RMDN3 ARRB1 ARRB2 COPS4 CCAR2 EIF2AK2 HELLS XPO7	1.57e-07	1284	232	27	17353931
Pubmed	Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.	SEC24A PSMD1 BIRC6 CLCC1 ITPR2 ITPR3 PSMD6 PHKA1 PTPN3 KARS1 CLCN7 GLYR1 SEC24B KIF14 ABCC1 DSP CTDSPL2 MINK1 PPP1R13B POSTN LNPEP CCAR2 EIF2AK4 HELLS	1.79e-07	1049	232	24	27880917
Pubmed	BioID-based intact cell interactome of the Kv1.3 potassium channel identifies a Kv1.3-STAT3-p53 cellular signaling pathway.	SEC24A PSMD1 RRM1 CLCC1 DDX6 PSMD6 DST SEC24B ROCK2 ANK2 COPB1 DSP MINK1 USP24 JMJD1C ABCE1 EPHA2 MACF1 XRCC6	3.46e-07	708	232	19	39231216
Pubmed	Acetylation of ELF5 suppresses breast cancer progression by promoting its degradation and targeting CCND1.	PDCD2 PSMD1 RRM1 ADAR DDX6 PSMD6 AP1M1 BSN ROCK2 COPB1 UFL1 DIS3 ABCE1 COPS4 CCAR2 NUB1 XRCC6 HELLS	4.84e-07	653	232	18	33742100
Pubmed	Qualitative and quantitative analyses of protein phosphorylation in naive and stimulated mouse synaptosomal preparations.	PSMD1 DST STXBP1 SYNJ1 BSN IQSEC3 ANK2 SLC25A4 MINK1 L1CAM PDPK2P MACF1 CEP170B	7.04e-07	347	232	13	17114649
Pubmed	Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.	ACACB LRRC49 PSMD1 RABGAP1 BIRC6 DST ALMS1 SYNJ1 KIF14 DSP USP24 ZDBF2 JMJD1C ARRB2	9.93e-07	418	232	14	34709266
Pubmed	Assembly of the U5 snRNP component PRPF8 is controlled by the HSP90/R2TP chaperones.	SEC24A RPS10 KIF4A PSMD1 RRM1 BIRC6 DDX6 HP1BP3 KARS1 DHCR24 AP1M1 TARBP1 ROCK2 SLC25A4 DSP USP24 UFL1 SRGAP2 DIS3 ARRB1 DNAJC17 ARRB2 MACF1 CCAR2 EIF2AK2 XRCC6 HELLS	1.03e-06	1415	232	27	28515276
Pubmed	A Multipronged Unbiased Strategy Guides the Development of an Anti-EGFR/EPHA2-Bispecific Antibody for Combination Cancer Therapy.	ACACB LRRC49 DST STXBP1 PIP5K1A ROCK2 ABCC1 MINK1 PPP1R13B UFL1 SRGAP2 ARRB2 EPHA2 MACF1	1.08e-06	421	232	14	36976175
Pubmed	Involvement of general control nonderepressible kinase 2 in cancer cell apoptosis by posttranslational mechanisms.	ARRB1 ARRB2 EIF2AK4	1.17e-06	4	232	3	25589675
Pubmed	Identification of a motif in the carboxyl terminus of beta -arrestin2 responsible for activation of JNK3.	MAP3K5 ARRB1 ARRB2	1.17e-06	4	232	3	11356842
Pubmed	beta-Arrestins facilitate ubiquitin-dependent degradation of apoptosis signal-regulating kinase 1 (ASK1) and attenuate H2O2-induced apoptosis.	MAP3K5 ARRB1 ARRB2	1.17e-06	4	232	3	19306926
Pubmed	Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.	ATP8B4 RPS10 PSMD1 ADAR DDX6 PSMD6 KARS1 GLYR1 DHCR24 KIF14 AP1M1 TLN2 BSN COPB1 DSP UFL1 COPS3 CWC22 DIS3 ABCE1 COPS4 CSTF1 PRKCD CCAR2 EIF2AK2 XRCC6 HELLS	1.18e-06	1425	232	27	30948266
Pubmed	Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB.	ACACB SEC24A KIF4A BIRC6 CLCC1 HP1BP3 PTPN3 DST SEC24B COPB1 CNTRL MINK1 WRN MUC16 BTBD3 EPHA2 CCAR2 HELLS XPO7	1.38e-06	777	232	19	35844135
Pubmed	N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.	ACACB KIF4A ADAR HP1BP3 KARS1 DST ALMS1 SYNJ1 SEC24B ANK2 COPB1 DSP SRGAP2 DIS3 USP14 ABCE1 COPS4 MACF1 ELF2 XRCC6 HELLS	1.44e-06	934	232	21	33916271
Pubmed	C5orf51 is a component of the MON1-CCZ1 complex and controls RAB7A localization and stability during mitophagy.	RABGAP1 CLCC1 ITPR2 ITPR3 DST CLCN7 SEC24B ZDHHC13 FNIP2 VPS26B VPS26A ATF6B RMDN3 LNPEP EPHA2	1.76e-06	504	232	15	34432599
Pubmed	The deubiquitinase TRABID stabilizes the K29/K48-specific E3 ubiquitin ligase HECTD1.	PDCD2 KIF4A ITPR2 PHKA1 DST PSME4 PAN2 USP24 ZFC3H1 NADSYN1	1.81e-06	212	232	10	33853758
Pubmed	ZZW-115-dependent inhibition of NUPR1 nuclear translocation sensitizes cancer cells to genotoxic agents.	KIF4A ADAR KRT80 DDX6 HP1BP3 ITPR3 DST KIF14 CTDSPL2 SRGAP2 CWC22 ARRB2 EPHA2 CSTF1 MACF1 EIF2AK2 XRCC6	2.53e-06	660	232	17	32780723
Pubmed	Neuron-specific protein network mapping of autism risk genes identifies shared biological mechanisms and disease-relevant pathologies.	ACACB PSMD1 RABGAP1 BIRC6 PSMD6 STXBP1 SYNJ1 GLYR1 AP1M1 TLN2 BSN NOS1 IQSEC3 ANK2 DSP MINK1 USP24 ZDBF2 SLC25A51 ABCE1 MACF1 SLC25A52 CEP170B	2.72e-06	1139	232	23	36417873
Pubmed	Global landscape of HIV-human protein complexes.	RABGAP1 DDX6 PTK2B KARS1 ALMS1 DHCR24 AP1M1 DSP COPS3 VIRMA ARRB2 COPS4 CCAR2 EIF2AK2	2.81e-06	457	232	14	22190034
Pubmed	Mechanosensitive brain tumor cells construct blood-tumor barrier to mask chemosensitivity.	PIEZO1 PTCH1 PIEZO2	2.90e-06	5	232	3	36323321
Pubmed	Inactivation of the FLCN tumor suppressor gene induces TFE3 transcriptional activity by increasing its nuclear localization.	MITF FNIP2 TFE3	2.90e-06	5	232	3	21209915
Pubmed	Viral delivery of L1CAM promotes axonal extensions by embryonic cerebral grafts in mouse brain.	DCC NRP1 L1CAM	2.90e-06	5	232	3	36963389
Pubmed	A scanning peptide array approach uncovers association sites within the JNK/beta arrestin signalling complex.	MAP3K5 ARRB1 ARRB2	2.90e-06	5	232	3	19782076
Pubmed	InsP₃receptors and Orai channels in pancreatic acinar cells: co-localization and its consequences.	ITPR2 ITPR3 XRCC6	2.90e-06	5	232	3	21568942
Pubmed	Rho-associated protein kinase-dependent moesin phosphorylation is required for PD-L1 stabilization in breast cancer.	RRM1 PSMD6 KARS1 DHCR24 ROCK2 DSP RADX DIS3 ABCE1 XPO7	2.96e-06	224	232	10	32941674
Pubmed	LCP1 preferentially binds clasped αMβ2 integrin and attenuates leukocyte adhesion under flow.	SEC24A PSMD1 BIRC6 ITGB3 KARS1 C3 COPB1 VPS26B USP24 VPS26A ARRB2 XPO7	3.95e-06	344	232	12	30333137
Pubmed	USP7 targets XIAP for cancer progression: Establishment of a p53-independent therapeutic avenue for glioma.	ACACB ADAR DST ASPM SDK2 DSP DDX60 MINK1 VIRMA MACF1	4.36e-06	234	232	10	36243803
Pubmed	In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.	ACACB MYO1A TRO PSMD1 CHD2 DCC HP1BP3 DST STXBP1 UMODL1 ASPM BSN ROCK2 ANK2 SLC25A4 DSP CTDSPL2 CNTRL ZFC3H1 ARRB1 MACF1 CFAP74 CCAR2 EIF2AK4 CFAP69 XRCC6	4.62e-06	1442	232	26	35575683
Pubmed	Viral Infection-Induced Differential Expression of LncRNAs Associated with Collagen in Mouse Placentas and Amniotic Sacs.	PSMD1 CLCN2 TRPM8 ZDHHC13 SLC25A51 CAPN7 SLC25A52	5.08e-06	100	232	7	26073538
Pubmed	β-arrestin-1 participates in thrombosis and regulates integrin aIIbβ3 signalling without affecting P2Y receptors desensitisation and function.	ITGB3 ARRB1 ARRB2	5.77e-06	6	232	3	22318609
Pubmed	Beta-arrestin-dependent regulation of the cofilin pathway downstream of protease-activated receptor-2.	LIMK1 ARRB1 ARRB2	5.77e-06	6	232	3	17500066
Pubmed	eIF2α phosphorylation controls thermal nociception.	ELF2 EIF2AK4 EIF2AK2	5.77e-06	6	232	3	27698114
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	CDK17 SEC24A DDX6 PTK2B PTPN3 DST ALMS1 SYNJ1 SEC24B KIF14 AP1M1 DSP MINK1 SRGAP2 VIRMA LIMK1 MACF1 NUB1 CEP170B	6.05e-06	861	232	19	36931259
Pubmed	ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.	PIEZO1 KIF4A RABGAP1 RRM1 CLCC1 NRP1 ITPR2 GLYR1 FAM20B ZDHHC13 ROCK2 ABCC1 L1CAM SLC43A3 ADAM12 ATF6B P2RX5 ABCE1 LNPEP EPHA2 COPS4 LRPAP1 EIF2AK2	6.47e-06	1201	232	23	35696571
Pubmed	H4K20me0 recognition by BRCA1-BARD1 directs homologous recombination to sister chromatids.	RPS10 KIF4A CHD2 ADAR HP1BP3 ITPR3 KARS1 DST GLYR1 DHCR24 MITF ABCC1 SLC25A4 DSP CTDSPL2 WRN ZFC3H1 JMJD1C TFE3 ELF2 LRIF1 JRKL XRCC6 HELLS	6.89e-06	1294	232	24	30804502
Pubmed	TNF-α inhibits glucocorticoid receptor-induced gene expression by reshaping the GR nuclear cofactor profile.	ACACB CHD2 ITPR3 STXBP1 BSN TARBP1 USP24 MUC16 NR4A3 ADAM30 ZDBF2 VIRMA TFE3 ANKRD36B ABCE1 HELLS	7.02e-06	638	232	16	31182584
Pubmed	Proximity biotinylation and affinity purification are complementary approaches for the interactome mapping of chromatin-associated protein complexes.	RPS10 KIF4A PSMD6 KARS1 DST ALMS1 GLYR1 KIF14 PIP5K1A C3 DNAJC17 ARRB2 ELF2 LRIF1 XRCC6 HELLS	8.04e-06	645	232	16	25281560
Pubmed	Construction of a multi-functional cDNA library specific for mouse pancreatic islets and its application to microarray.	ABCA1 ADAR ITPR3 ABCC1 ANK2 XK ATF6B JMJD1C TTLL7 LIF DNAJC17 TNFAIP2	8.47e-06	371	232	12	15747579
Pubmed	A High-Density Human Mitochondrial Proximity Interaction Network.	SEC24A LRRC49 PSMD1 RABGAP1 BIRC6 CLCC1 ITPR2 ITPR3 PSMD6 DST ALMS1 ALDH1L2 SEC24B SLC25A4 UFL1 ZDBF2 SLC25A51 RMDN3 ARRB2 CLYBL ABCE1 PRKCD CCAR2 TRAK2 EIF2AK2 XRCC6	8.82e-06	1496	232	26	32877691
Pubmed	Loss of ER retention motif of AGR2 can impact mTORC signaling and promote cancer metastasis.	RPS10 PSMD1 DDX6 HP1BP3 PSMD6 DST DOCK2 COPB1 DSP CNTRL COPS3 EPG5 USP14 RMDN3 ABCE1 MACF1 MYO16 XRCC6	9.27e-06	807	232	18	30575818
Pubmed	Direct interaction between hnRNP-M and CDC5L/PLRG1 proteins affects alternative splice site choice.	KIF4A PSMD1 TUBGCP4 DDX6 TLN2 DOCK2 ROCK2 COPB1 DSP USP24 COPS3 MACF1 TNFAIP2 XRCC6 HELLS	9.91e-06	582	232	15	20467437
Pubmed	Analysis of hedgehog interacting protein in the brain and its expression in nitric oxide synthase-positive cells.	PTCH1 NOS1 HHIP	1.01e-05	7	232	3	16272887
Pubmed	PlexinA1 is crucial for the midline crossing of callosal axons during corpus callosum development in BALB/cAJ mice.	DCC NRP1 L1CAM	1.01e-05	7	232	3	31430342
Pubmed	The HIV-1 Tat protein recruits a ubiquitin ligase to reorganize the 7SK snRNP for transcriptional activation.	CDK17 RPS10 PSMD1 CHD2 USP9Y RRM1 KRT80 DDX6 HP1BP3 PSMD6 KARS1 GLYR1 PIP5K1A AP1M1 SLC25A4 COPB1 DSP RADX MACF1 CCAR2 EIF2AK2 XRCC6	1.10e-05	1153	232	22	29845934
Pubmed	ARHGAP24 represses β-catenin transactivation-induced invasiveness in hepatocellular carcinoma mainly by acting as a GTPase-independent scaffold.	PSMD1 AK9 RRM1 ADAR HP1BP3 COPB1 UFL1 DIS3 USP14 ZNF716 ABCE1 CCAR2 XRCC6	1.22e-05	451	232	13	36168627
Pubmed	FBW7 suppresses ovarian cancer development by targeting the N6-methyladenosine binding protein YTHDF2.	RPS10 ADAR HP1BP3 KARS1 GLYR1 AP1M1 C3 COPB1 UFL1 DIS3 MACF1 EIF2AK4 EIF2AK2 CEP170B HELLS	1.44e-05	601	232	15	33658012
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	PIEZO1 KARS1 DST PSME4 NBEAL2 DHCR24 FAM20B PAN2 BSN SDK2 UFL1 CWC22 DIS3 EIF2AK4	1.47e-05	529	232	14	14621295
Pubmed	The E3 ubiquitin ligase HECTD1 contributes to cell proliferation through an effect on mitosis.	KIF4A ADAR BIRC6 DDX6 HP1BP3 KARS1 GLYR1 ASPM SLC25A4 RADX WRN ZFC3H1 VIRMA MACF1 CCAR2 EIF2AK2 XRCC6	1.57e-05	759	232	17	35915203
Pubmed	A high-throughput approach for measuring temporal changes in the interactome.	SEC24A RPS10 USP25 PSMD1 RABGAP1 RRM1 BIRC6 PSMD6 KARS1 PSME4 AP1M1 ROCK2 COPB1 USP24 COPS3 VPS26A DIS3 USP14 ABCE1 LNPEP COPS4 MACF1 CCAR2 XRCC6 XPO7	1.61e-05	1455	232	25	22863883
Pubmed	Two-Dimensional Fractionation Method for Proteome-Wide Cross-Linking Mass Spectrometry Analysis.	GIN1 TRO RPS10 RABGAP1 RRM1 ADAR DDX6 PSMD6 KARS1 AP1M1 TLN2 ROCK2 SLC25A4 COPB1 DSP MACF1 CCAR2 XRCC6	1.77e-05	847	232	18	35235311
Pubmed	Integrative analysis of kinase networks in TRAIL-induced apoptosis provides a source of potential targets for combination therapy.	PXK MAP3K5 PSMD6 DST DHCR24 DSP MINK1 COPS3 ZFC3H1 COPS4 CEP170B XRCC6	1.83e-05	401	232	12	25852190
Pubmed	Identifying biological pathways that underlie primordial short stature using network analysis.	RPS10 PSMD1 ADAR KRT80 DDX6 HP1BP3 NRP1 ITPR2 ITPR3 PSMD6 DST KIF14 COPB1 DSP UFL1 MACF1 CCAR2 XRCC6 HELLS XPO7	2.01e-05	1024	232	20	24711643
Pubmed	Synaptic GAP and GEF Complexes Cluster Proteins Essential for GTP Signaling.	PTK2B STXBP1 SYNJ1 TLN2 IQSEC3 ANK2 MINK1 SRGAP2 MACF1 CEP170B	2.14e-05	281	232	10	28706196
Pubmed	Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.	CDK17 PIEZO1 RPS10 RRM1 CLCC1 HP1BP3 ITPR2 ITPR3 CLCN7 GLYR1 ASPM PIP5K1A ANK2 MINK1 UFL1 ZFC3H1 ATF6B DNAJC17 LNPEP EPHA2 COPS4 MACF1 LRPAP1 XRCC6 HELLS	2.30e-05	1487	232	25	33957083
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	PDE9A TTC21A PSMD1 CHD2 RABGAP1 CLCC1 HP1BP3 NRP1 GLYR1 PIP5K1A CAB39L ZDHHC13 MINK1 SRGAP2 JMJD1C RANBP17 USP14 NADSYN1 ARRB1 ARRB2 MACF1 EIF2AK4 CFAP69 CEP170B XPO7	2.36e-05	1489	232	25	28611215
Pubmed	An Interaction Landscape of Ubiquitin Signaling.	CDK17 USP25 PSMD1 ITPR3 PSMD6 DST USP24 PDPK2P USP14 COPS4 MACF1 NUB1 XRCC6	2.39e-05	481	232	13	28190767
Pubmed	A human MAP kinase interactome.	RIPOR2 PSMD1 MAP3K5 PTPN3 DST DSP CNTRL PPP1R13B RMDN3 ARRB1 ARRB2 MACF1 LRPAP1	2.66e-05	486	232	13	20936779
Pubmed	The Hsp70-Hsp90 co-chaperone Hop/Stip1 shifts the proteostatic balance from folding towards degradation.	RPS10 PSMD1 RRM1 ADAR DDX6 PSMD6 KARS1 AP1M1 COPB1 USP24 UFL1 DIS3 CCAR2 XRCC6 HELLS	2.88e-05	638	232	15	33239621
Pubmed	Comparative proximity biotinylation implicates the small GTPase RAB18 in sterol mobilization and biosynthesis.	SEC24A RABGAP1 CLCC1 ITPR3 DST CLCN7 SEC24B ROCK2 SLC25A4 DSP UFL1 ZDBF2 USP14 RMDN3	3.20e-05	568	232	14	37774976
Pubmed	A human skeletal muscle interactome centered on proteins involved in muscular dystrophies: LGMD interactome.	MYOM1 PSMD1 CHD2 BIRC6 MAP3K5 KARS1 DST ALMS1 ANK2 DSP JMJD1C MACF1 XRCC6	3.35e-05	497	232	13	23414517
Pubmed	Human transcription factor protein interaction networks.	ACACB SEC24A LRRC49 RPS10 PSMD1 HP1BP3 PSMD6 DST ALMS1 GLYR1 SEC24B MITF COPB1 RADX PPP1R13B JMJD1C TFE3 CSTF1 ELF1 CCAR2 ELF2 LRIF1 XRCC6 HELLS	3.44e-05	1429	232	24	35140242
Pubmed	C9orf72 protein quality control by UBR5-mediated heterotypic ubiquitin chains.	RPS10 PSMD1 RRM1 BIRC6 DDX6 PSMD6 KARS1 PSME4 DHCR24 AP1M1 DDX12P SLC25A4 COPB1 DSP RADX DIS3 ABCE1 CSTF1 CCAR2 NUB1 XRCC6 HELLS	4.05e-05	1257	232	22	37317656
Pubmed	Proteomic analysis and identification of cellular interactors of the giant ubiquitin ligase HERC2.	PSMD1 BIRC6 KRT80 ITPR2 PHKA1 ASPM RADX	4.34e-05	139	232	7	25476789
Pubmed	Isolation of human proteasomes and putative proteasome-interacting proteins using a novel affinity chromatography method.	USP25 PSMD1 PSMD6 PSME4 USP14	4.35e-05	58	232	5	19013454
Pubmed	Ask1 regulates murine platelet granule secretion, thromboxane A2 generation, and thrombus formation.	ITGB3 MAP3K5	4.43e-05	2	232	2	28028021
Pubmed	ARRB2 (β-Arrestin-2) Deficiency Alters Fluid Homeostasis and Blood Pressure Regulation.	ARRB1 ARRB2	4.43e-05	2	232	2	36215165
Pubmed	Critical regulation of CD4+ T cell survival and autoimmunity by beta-arrestin 1.	ARRB1 ARRB2	4.43e-05	2	232	2	17618287
Pubmed	Single molecule recognition between cytochrome C 551 and gold-immobilized azurin by force spectroscopy.	ABCA1 LIMK1	4.43e-05	2	232	2	16192283
Pubmed	Identification of ADAR1 adenosine deaminase dependency in a subset of cancer cells.	ADAR EIF2AK2	4.43e-05	2	232	2	30575730
Pubmed	Acf7 (MACF) is an actin and microtubule linker protein whose expression predominates in neural, muscle, and lung development.	DST MACF1	4.43e-05	2	232	2	11002341
Pubmed	Carbachol stimulates TYR phosphorylation and association of PKCdelta and PYK2 in pancreas.	PTK2B PRKCD	4.43e-05	2	232	2	11352632
Pubmed	G protein-coupled receptors. III. New roles for receptor kinases and beta-arrestins in receptor signaling and desensitization.	ARRB1 ARRB2	4.43e-05	2	232	2	9668034
Pubmed	Metabolic effects of skeletal muscle-specific deletion of beta-arrestin-1 and -2 in mice.	ARRB1 ARRB2	4.43e-05	2	232	2	31622341
Pubmed	Differential expression of PIEZO1 and PIEZO2 mechanosensitive channels in ocular tissues implicates diverse functional roles.	PIEZO1 PIEZO2	4.43e-05	2	232	2	37820892
Pubmed	Desensitization, internalization, and signaling functions of beta-arrestins demonstrated by RNA interference.	ARRB1 ARRB2	4.43e-05	2	232	2	12582207
Pubmed	Contributions of protein kinases and β-arrestin to termination of protease-activated receptor 2 signaling.	ARRB1 ARRB2	4.43e-05	2	232	2	26927499
Pubmed	Cloning and characterization of human type 2 and type 3 inositol 1,4,5-trisphosphate receptors.	ITPR2 ITPR3	4.43e-05	2	232	2	8081734
Pubmed	Deficiency of β-Arrestin 2 in Dendritic Cells Contributes to Autoimmune Diseases.	ARRB1 ARRB2	4.43e-05	2	232	2	30541881
Pubmed	β-Arrestins regulate human cardiac fibroblast transformation and collagen synthesis in adverse ventricular remodeling.	ARRB1 ARRB2	4.43e-05	2	232	2	25134464
Pubmed	Regulation of lipopolysaccharide-induced inflammatory response and endotoxemia by beta-arrestins.	ARRB1 ARRB2	4.43e-05	2	232	2	20589830
Pubmed	β-Arrestin2 mediates the initiation and progression of myeloid leukemia.	ARRB1 ARRB2	4.43e-05	2	232	2	22773819
Pubmed	The role of PIEZO ion channels in the musculoskeletal system.	PIEZO1 PIEZO2	4.43e-05	2	232	2	36717101
Pubmed	Unique Roles of β-Arrestin in GPCR Trafficking Revealed by Photoinducible Dimerizers.	ARRB1 ARRB2	4.43e-05	2	232	2	29330504
Pubmed	SLC25A51 is a mammalian mitochondrial NAD+ transporter.	SLC25A51 SLC25A52	4.43e-05	2	232	2	32906142
Pubmed	Self-amplifying loop of NF-κB and periostin initiated by PIEZO1 accelerates mechano-induced senescence of nucleus pulposus cells and intervertebral disc degeneration.	PIEZO1 POSTN	4.43e-05	2	232	2	35619555
Pubmed	TRAK2, a novel regulator of ABCA1 expression, cholesterol efflux and HDL biogenesis.	ABCA1 TRAK2	4.43e-05	2	232	2	28655204
Pubmed	A Plug-and-Latch Mechanism for Gating the Mechanosensitive Piezo Channel.	PIEZO1 PIEZO2	4.43e-05	2	232	2	32142647
Pubmed	Conserved intermolecular salt bridge required for activation of protein kinases PKR, GCN2, and PERK.	EIF2AK4 EIF2AK2	4.43e-05	2	232	2	17202131
Pubmed	Ovarian stimulation with GnRH agonist, but not GnRH antagonist, partially restores the expression of endometrial integrin beta3 and leukaemia-inhibitory factor and improves uterine receptivity in mice.	ITGB3 LIF	4.43e-05	2	232	2	16790614
Pubmed	Trophinin-mediated cell adhesion induces apoptosis of human endometrial epithelial cells through PKC-δ.	TRO PRKCD	4.43e-05	2	232	2	21191175
Pubmed	Differential promoter usages of PTCH1 and down regulation of HHIP are associated with HNSCC progression.	PTCH1 HHIP	4.43e-05	2	232	2	35276608
Pubmed	β-arrestins negatively control human adrenomedullin type 1-receptor internalization.	ARRB1 ARRB2	4.43e-05	2	232	2	28427767
Pubmed	Beta-arrestins 1 and 2 are associated with nicotine dependence in European American smokers.	ARRB1 ARRB2	4.43e-05	2	232	2	17579607
Interaction	GRK2 interactions	PTCH1 DDX6 FBXO25 SCNN1B CCR4 EDNRB ARRB1 ARRB2 EPHA2 PRKCD	9.07e-07	119	225	10	int:GRK2
Interaction	MYH9 interactions	USP45 MYOM1 RPS10 USP25 PSMD1 ITGB3 ITPR2 ITPR3 PSMD6 FBXO25 DST CLCN2 PAN2 KIF14 PIP5K1A CTDSPL2 UFL1 COPS3 VIRMA USP14 ARRB1 ARRB2 COPS4 MACF1 XRCC6	1.25e-06	754	225	25	int:MYH9
Interaction	YWHAG interactions	CDK17 RIPOR2 SEC24A PSMD1 RRM1 DDX6 MAP3K5 PTPN3 DST ALMS1 SYNJ1 SEC24B MITF KIF14 AP1M1 COPB1 DSP MINK1 USP24 SRGAP2 CWC22 VIRMA TFE3 TTLL7 RMDN3 ARRB1 ARRB2 MACF1 PRKCD NUB1 CEP170B	2.43e-05	1248	225	31	int:YWHAG
Interaction	PSMC3 interactions	PSMD1 PTCH1 DDX6 MAP3K5 ITPR2 PSMD6 FBXO25 PSME4 KIF14 UFL1 VIRMA USP14 CCAR2 ELF2 EIF2AK4 LRIF1	2.48e-05	425	225	16	int:PSMC3
Interaction	EED interactions	ACACB SEC24A RPS10 KIF4A PSMD1 CHD2 RRM1 ADAR BIRC6 DDX6 HP1BP3 PSMD6 PTK2B SYNJ1 GLYR1 SEC24B AP1M1 SLC25A4 COPB1 DSP COPS3 CWC22 VIRMA DIS3 USP14 ABCE1 UNC45B MACF1 LRPAP1 CCAR2 CEP170B XRCC6 HELLS XPO7	2.88e-05	1445	225	34	int:EED
Interaction	GJA1 interactions	SEC24A RABGAP1 CLCC1 ITPR2 ITPR3 DST STXBP1 SEC24B PIP5K1A C3 ROCK2 ABCC1 SDK2 MINK1 UFL1 LNPEP EPHA2 MACF1 KCTD2	3.18e-05	583	225	19	int:GJA1
Interaction	PSMD2 interactions	SEC24A PSMD1 PTCH1 ITGB3 PSMD6 FBXO25 PSME4 KIF14 ABCC1 COPB1 UFL1 VIRMA USP14 CCAR2 NUB1 LRIF1	3.28e-05	435	225	16	int:PSMD2
Interaction	SIRT7 interactions	RPS10 KIF4A PSMD1 CHD2 BIRC6 HP1BP3 ITPR3 KARS1 DST GLYR1 KIF14 COPB1 DSP USP24 VIRMA DIS3 ABCE1 COPS4 MACF1 CCAR2 XRCC6 XPO7	3.30e-05	744	225	22	int:SIRT7
Interaction	PHF21A interactions	ACACB LRRC49 PSMD1 RABGAP1 BIRC6 DST ALMS1 SYNJ1 KIF14 DSP USP24 ZDBF2 JMJD1C ARRB2	3.36e-05	343	225	14	int:PHF21A
Interaction	PGBD5 interactions	PIP5K1A VIRMA RMDN3	4.65e-05	7	225	3	int:PGBD5
Interaction	CLTC interactions	RPS10 USP25 PTCH1 RRM1 ADAR ITGB3 SYNJ1 SEC24B PAN2 KIF14 CNTRL UFL1 VIRMA TFE3 BTBD3 ARRB1 ARRB2 EPHA2 CCAR2 XRCC6	4.90e-05	655	225	20	int:CLTC
Interaction	EDNRB interactions	PXK NRP1 EDNRB LNPEP XPO7	7.01e-05	39	225	5	int:EDNRB
Interaction	IMPDH2 interactions	LRRC49 PSMD1 PTCH1 PSMD6 FBXO25 ALMS1 SYNJ1 KIF14 PIP5K1A DSP UFL1 VIRMA USP14 LIMK1 SLC25A44	8.07e-05	420	225	15	int:IMPDH2
Interaction	AP2B1 interactions	PSMD1 TUBGCP4 ALMS1 SYNJ1 KIF14 AP1M1 UFL1 VIRMA ARRB1 ARRB2 LNPEP EPHA2 CEP170B XPO7	8.28e-05	373	225	14	int:AP2B1
Interaction	ATP2A1 interactions	SEC24A PIEZO1 CLCC1 ITPR2 ITPR3 CLCN7 DHCR24 SEC24B KIF14 SLC25A17 ABCC1 UFL1 FAR2 LNPEP PRKCD	8.73e-05	423	225	15	int:ATP2A1
Interaction	CGAS interactions	USP25 CHD2 HP1BP3 CLCN7 KIF14 DDX60L DDX60 UFL1 VIRMA ABCE1 CAPN7 LRIF1 MX2	8.91e-05	329	225	13	int:CGAS
Interaction	CDC5L interactions	RPS10 KIF4A PSMD1 TUBGCP4 DDX6 DST KIF14 TLN2 ROCK2 COPB1 DSP WRN USP24 PPP1R13B UFL1 ZDBF2 CWC22 VIRMA DNAJC17 MACF1 TNFAIP2 EIF2AK2 HELLS	9.20e-05	855	225	23	int:CDC5L
Interaction	NR3C1 interactions	ACACB CHD2 ITPR3 KARS1 STXBP1 C3 BSN TARBP1 FNIP2 ABCC1 SLC25A4 DSP USP24 MUC16 NR4A3 ADAM30 ZDBF2 VIRMA JMJD1C TFE3 ANKRD36B ARRB1 ABCE1 LRIF1 HELLS	9.50e-05	974	225	25	int:NR3C1
Interaction	NUP155 interactions	SEC24A LRRC49 CLCC1 ITPR2 ITPR3 ALMS1 CLCN7 DHCR24 SEC24B KIF14 C3 DDX60 UFL1 VIRMA RMDN3 EPHA2	9.73e-05	477	225	16	int:NUP155
Interaction	UBA1 interactions	TUBGCP4 ITGB3 KARS1 MYLK4 KIF14 AP1M1 TRPM8 VIRMA TFE3 USP14 LRPAP1 XRCC6 HELLS XPO7	1.01e-04	380	225	14	int:UBA1
Interaction	VIM interactions	RPS10 PSMD1 TUBGCP4 PTCH1 ITGB3 FBXO25 KARS1 CLCN2 SYNJ1 PAN2 KIF14 ROCK2 DSP CNTRL UFL1 VIRMA TFE3 USP14 ARRB1 ARRB2 ABCE1 LRIF1	1.03e-04	804	225	22	int:VIM
Interaction	YWHAH interactions	CDK17 SEC24A DDX6 MAP3K5 PTPN3 DST ALMS1 SYNJ1 SEC24B MITF KIF14 DSP CNTRL MINK1 SRGAP2 CWC22 VIRMA TFE3 TTLL7 RMDN3 ARRB1 ARRB2 ABCE1 MACF1 CCAR2 NUB1 CEP170B	1.07e-04	1102	225	27	int:YWHAH
Interaction	PSMC5 interactions	PSMD1 PTCH1 BIRC6 MAP3K5 PSMD6 FBXO25 PSME4 ASPM PAN2 KIF14 ABCC1 UFL1 VIRMA USP14 CCAR2 NUB1	1.15e-04	484	225	16	int:PSMC5
Interaction	MAGEA9 interactions	ITPR2 ITPR3 STXBP1 SYNJ1 ASPM KIF14 ZDBF2 ZFC3H1 EIF2AK4 HELLS	1.21e-04	208	225	10	int:MAGEA9
Interaction	KCNA3 interactions	SEC24A PSMD1 CHD2 RRM1 CLCC1 DDX6 PSMD6 DST SEC24B TLN2 BSN ROCK2 ANK2 COPB1 DSP MINK1 USP24 JMJD1C ABCE1 EPHA2 MACF1 EIF2AK4 XRCC6	1.21e-04	871	225	23	int:KCNA3
Interaction	AGAP2 interactions	TRO PTK2B STXBP1 SYNJ1 TLN2 IQSEC3 ANK2 MINK1 MACF1 CEP170B	1.31e-04	210	225	10	int:AGAP2
Interaction	PSMC2 interactions	PSMD1 PTCH1 DDX6 MAP3K5 PSMD6 PSME4 KIF14 ROCK2 UFL1 VPS26A VIRMA USP14 ABCE1 CCAR2	1.43e-04	393	225	14	int:PSMC2
GeneFamily	Ubiquitin specific peptidases	USP45 USP25 USP9Y PAN2 USP24 USP14	7.62e-06	56	153	6	366
GeneFamily	EF-hand domain containing\|Plakins	DST DSP MACF1	3.23e-05	8	153	3	939
GeneFamily	Inositol 1,4,5-triphosphate receptors\|Protein phosphatase 1 regulatory subunits	ITPR2 ITPR3	2.12e-04	3	153	2	297
GeneFamily	DNA helicases	CHD2 XRCC6 HELLS	3.70e-04	17	153	3	1167
GeneFamily	Classical arrestins	ARRB1 ARRB2	4.22e-04	4	153	2	1312
GeneFamily	Ankyrin repeat domain containing\|FERM domain containing	FRMD7 PTK2B PTPN3 TLN2	8.39e-04	50	153	4	1293
GeneFamily	ADAM metallopeptidase domain containing\|CD molecules	ADAM8 ADAM30 ADAM12	1.50e-03	27	153	3	47
GeneFamily	Fibronectin type III domain containing	MYOM1 DCC SDK2 L1CAM EPHA2 ANKFN1	2.42e-03	160	153	6	555
GeneFamily	COP9 signalosome	COPS3 COPS4	2.46e-03	9	153	2	932
GeneFamily	C3 and PZP like, alpha-2-macroglobulin domain containing	C3 PZP	2.46e-03	9	153	2	1234
GeneFamily	Chloride voltage-gated channels	CLCN2 CLCN7	3.06e-03	10	153	2	302
GeneFamily	Ankyrin repeat domain containing	ZDHHC13 ASB17 ANK2 PPP1R13B ANKRD36B ANKFN1 MYO16	4.59e-03	242	153	7	403
GeneFamily	DEAD-box helicases	DDX6 DDX12P DDX60	5.36e-03	42	153	3	499
GeneFamily	Proteasome	PSMD1 PSMD6 PSME4	5.72e-03	43	153	3	690
Coexpression	HOWARD_NEUTROPHIL_INACT_MONOV_INFLUENZA_A_INDONESIA_05_2005_H5N1_AGE_18_49YO_1DY_UP	ARMH1 KARS1 SERPINB9 PAN2 DDX60L TARBP1 DDX60 CNTRL CCRL2 SLC43A3 EPG5 LIMK1 SMTNL1 NUB1 EIF2AK2	2.50e-06	394	231	15	M40996
Coexpression	DESCARTES_FETAL_STOMACH_CILIATED_EPITHELIAL_CELLS	CFAP251 TTC21A TSPAN19 AK9 ODAD4 CFAP47 IQCH CFAP43 TMEM232 CFAP74 CFAP69 ANKFN1	2.72e-05	317	231	12	M40298
Coexpression	BUSSLINGER_GASTRIC_IMMUNE_CELLS	CDK17 RIPOR2 PIEZO1 USP25 CHD2 ADAM8 IL18RAP ADAR BIRC6 DDX6 ITPR2 PTK2B SERPINB9 NBEAL2 AP1M1 DOCK2 COPB1 CNTRL USP24 VPS26A ZFC3H1 JMJD1C EPG5 ARRB2 P2RX5 LNPEP MACF1 ELF1 XRCC6	5.55e-05	1492	231	29	M40023
Coexpression	GAO_ESOPHAGUS_25W_C1_CILIATED_EPITHELIAL_CELLS	TTC21A TSPAN19 AK9 ODAD4 ALMS1 PZP CFAP47 IQCH USP24 CFAP43 TTLL7 TMEM232 MACF1 CFAP69	6.29e-05	459	231	14	M39136
Coexpression	GSE2770_TGFB_AND_IL4_VS_IL12_TREATED_ACT_CD4_TCELL_2H_DN	ADAM8 ITPR2 GHRH PSME4 CAB39L CCRL2 SLC25A44 KCTD2 LRIF1	6.70e-05	197	231	9	M6075
Coexpression	GSE13522_CTRL_VS_T_CRUZI_BRAZIL_STRAIN_INF_SKIN_DN	ABCA1 ATP8B4 USP25 GHRH BBOX1 ANK2 EDNRB BTBD3 DNAH17	7.24e-05	199	231	9	M2921
Coexpression	GSE12392_CD8A_POS_VS_NEG_SPLEEN_DC_UP	USP25 TUBGCP4 CLCN7 SCG2 C3 ABCC1 VPS26A COPS4 PRKCD	7.52e-05	200	231	9	M7135
Coexpression	GSE37301_COMMON_LYMPHOID_PROGENITOR_VS_CD4_TCELL_DN	KIF4A RRM1 ITPR2 DHCR24 KIF14 ZDHHC13 VPS26A JMJD1C ANKRD36B	7.52e-05	200	231	9	M8869
Coexpression	GSE19888_CTRL_VS_TCELL_MEMBRANES_ACT_MAST_CELL_PRETREAT_A3R_INH_DN	ADAR PTK2B SERPINB9 STXBP1 DDX60 CCRL2 SLC25A44 TNFAIP2 EIF2AK2	7.52e-05	200	231	9	M7336
Coexpression	GSE34156_NOD2_LIGAND_VS_TLR1_TLR2_LIGAND_6H_TREATED_MONOCYTE_UP	ADAR GHRH SERPINB9 STXBP1 RMDN3 SLC25A44 NUB1 EIF2AK2 MX2	7.52e-05	200	231	9	M8690
Coexpression	GSE3994_WT_VS_PAC1_KO_ACTIVATED_MAST_CELL_DN	ADAM8 BBS9 ITGB3 CLCC1 MAP3K5 PTK2B PAN2 CTDSPL2 NUB1	7.52e-05	200	231	9	M6372
Coexpression	GSE32423_CTRL_VS_IL7_IL4_MEMORY_CD8_TCELL_UP	CDK17 ATP8B4 PIEZO1 BBS9 CFAP47 CTDSPL2 MUC16 CAPN7 ELF2	7.52e-05	200	231	9	M5087
Coexpression	GSE36527_CD69_NEG_VS_POS_TREG_CD62L_LOS_KLRG1_NEG_UP	RPS10 GPR87 ADAR HAVCR1 DDX60 CCRL2 CWC22 EIF2AK2 MX2	7.52e-05	200	231	9	M9030
Coexpression	DAZARD_RESPONSE_TO_UV_NHEK_DN	MAP3K5 PTPN3 DST KIF14 USP24 ZFC3H1 BTBD3 SLC25A44 PRKCD ELF1 ELF2	7.81e-05	300	231	11	M8702
Coexpression	MITSIADES_RESPONSE_TO_APLIDIN_DN	KIF4A RRM1 DHCR24 FAM20B ASPM KIF14 DSP MACF1 EIF2AK2 HELLS	8.09e-05	250	231	10	M11318
Coexpression	ERWIN_COHEN_BLOOD_TC_83_AGE_23_48YO_VACCINATED_VS_CONTROL_2DY_UP	TTC21A DDX60L DDX60 SRGAP2 NUB1 EIF2AK2 MX2	9.15e-05	119	231	7	M41139
CoexpressionAtlas	alpha beta T cells, T.8.TI.B16, 4- 8+ TCR+ 45+, B16 Melanoma Tumor, avg-2	ATP8B4 KIF4A PTCH1 RRM1 ADAM8 IL18RAP NRP1 SERPINB9 DHCR24 ASPM KIF14 NR4A3 MX2 HELLS	2.00e-05	359	216	14	GSM605773_500
CoexpressionAtlas	FacebaseRNAseq_e9.5_Mandibular Arch_top-relative-expression-ranked_2500_k-means-cluster#2	TRO KIF4A PSMD1 CHD2 ITPR2 STXBP1 SEC24B FNIP2 COPB1 CTDSPL2 USP24 JMJD1C RMDN3 PTCD2 SLC25A44 MACF1 CFAP74 EIF2AK4	2.01e-05	564	216	18	Facebase_RNAseq_e9.5_Mandibular Arch_2500_K2
ToppCell	IPF-Epithelial-Ciliated\|Epithelial / Disease state, Lineage and Cell class	CFAP251 TSPAN19 AK9 ODAD4 BBS9 CFAP47 IQCH CFAP43 TMEM232 CFAP74 CFAP69 ANKFN1	4.60e-10	193	232	12	ad58f5080e0ba65c845056ea6b79037b636e9c64
ToppCell	mild\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	CHD2 ADAR BIRC6 DDX6 DDX60L DDX60 ZFC3H1 JMJD1C MACF1 NUB1 EIF2AK2 MX2	6.92e-10	200	232	12	12f1685ce8f218433068e090c9d839cd5a1910bf
ToppCell	Calu_3-infected\|Calu_3 / Cell line, Condition and Strain	CHD2 ADAR DST DDX60L DSP DDX60 JMJD1C NUB1 TNFAIP2 EIF2AK2 MX2	3.53e-09	183	232	11	8f7f5000645f24f20a8d7700c4df1f8953a1780b
ToppCell	NS-moderate-d_16-33-Epithelial-Ciliated\|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	CFAP251 TTC21A LRRC49 TSPAN19 PZP CFAP47 CFAP43 TMEM232 CFAP74 CFAP69 ANKFN1	3.96e-09	185	232	11	5e689c2fb36ce3ac2adc8d15f67107f21cf68868
ToppCell	IPF-Epithelial-Ciliated\|IPF / Disease state, Lineage and Cell class	CFAP251 TSPAN19 AK9 ODAD4 CFAP47 IQCH CFAP43 TMEM232 CFAP74 CFAP69 ANKFN1	5.83e-09	192	232	11	354adc1354bf596fbc60dd45c0169688e6f45165
ToppCell	Control-Epithelial-Ciliated\|Epithelial / Disease state, Lineage and Cell class	CFAP251 TSPAN19 AK9 ODAD4 CFAP47 IQCH CFAP43 TMEM232 CFAP74 CFAP69 ANKFN1	6.16e-09	193	232	11	0e37d454f3735edd936ee9a5f5f516ac3aad400e
ToppCell	3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.0.2\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CFAP251 TTC21A TSPAN19 AK9 PZP MUC16 CFAP43 CFAP74 CFAP69 ANKFN1	2.14e-08	169	232	10	14aadc2d1bf66eb47dac33b4d61ddb3c942caa4f
ToppCell	systemic_lupus_erythematosus-flare-Lymphocytic_B-plasmablast\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	NUGGC KIF4A DCC ALDH1L2 ASPM SCNN1B KIF14 SLC25A4 MUC16 XK	3.14e-08	176	232	10	dc4e939a07bad21ab36181f9588df3fa662f9a92
ToppCell	droplet-Marrow-nan-3m\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	BIRC6 DDX6 HP1BP3 ROCK2 CTDSPL2 CNTRL JMJD1C LNPEP MACF1 ELF1	4.78e-08	184	232	10	1154a5ad7b8512272b7476f949ddac350910bfb7
ToppCell	COPD-Epithelial-Ciliated\|Epithelial / Disease state, Lineage and Cell class	CFAP251 TSPAN19 AK9 ODAD4 CFAP47 IQCH CFAP43 TMEM232 CFAP74 ANKFN1	6.16e-08	189	232	10	3e77883db34722b9ce0a03ea74caefc92dc7feff
ToppCell	nucseq-Epithelial-Epithelial_Airway\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	CFAP251 TSPAN19 CFAP47 IQCH MUC16 CFAP43 TMEM232 CFAP74 CFAP69 ANKFN1	6.80e-08	191	232	10	1c528f72c9ef3ef3a850b05e4a9715190832270c
ToppCell	Mild/Remission-B_activate-7\|World / disease group and sub_cluster of B and Plasma cells(res = 0.5)	RIPOR2 USP25 DDX60L DSP DDX60 JMJD1C ELF1 NUB1 EIF2AK2 MX2	6.80e-08	191	232	10	382686d62f7b8576c44bb9726a4e10dc26fd348e
ToppCell	nucseq-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	CFAP251 TSPAN19 CFAP47 IQCH MUC16 CFAP43 TMEM232 CFAP74 CFAP69 ANKFN1	6.80e-08	191	232	10	e417bf491f8b8d7838a61f7f4f6b1740ba97aa3f
ToppCell	nucseq-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	CFAP251 TSPAN19 CFAP47 IQCH MUC16 CFAP43 TMEM232 CFAP74 CFAP69 ANKFN1	6.80e-08	191	232	10	9d31c8424d35bdc0c27188b68bfd0f731af3600b
ToppCell	COPD-Epithelial-Ciliated\|World / Disease state, Lineage and Cell class	CFAP251 TSPAN19 CFAP47 IQCH MUC16 CFAP43 TMEM232 CFAP74 CFAP69 ANKFN1	7.14e-08	192	232	10	eab1105cd1a98cfcd3d74dc5c9b89e1799bba59e
ToppCell	3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CFAP251 TTC21A TSPAN19 AK9 ODAD4 CFAP47 MUC16 CFAP43 CFAP74 CFAP69	7.87e-08	194	232	10	4a2c127c90d1fefe604fcb9e796577d21b489dd6
ToppCell	Mild-CD4+_T_activated\|World / Disease group and Cell class	RIPOR2 TTC21A ADAR DDX60L DDX60 LNPEP ELF1 NUB1 EIF2AK2 MX2	8.66e-08	196	232	10	417b4fc2e4388f34c410576131b02936f93e46b6
ToppCell	LPS_IL1RA-Mesenchymal_fibroblastic-Fibroblasts-Activated_MatrixFB\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	ABCA1 MAP3K5 C3 PZP SDK2 ANK2 LIF TNFAIP2 CFAP69 MYO16	9.98e-08	199	232	10	8b86c69aaf60feff53aa782559cfece7342a23de
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-TAM-MG-TAM-MG_pro-infl_II\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	ITPR2 SERPINB9 TLN2 C3 DOCK2 GPR34 NR4A3 SRGAP2 ELF1 MX2	9.98e-08	199	232	10	e7faf7d0cb43cf93149c446e5f718f84fa85477c
ToppCell	VE\|World / Condition, Cell_class and T cell subcluster	RIPOR2 RPS10 ADAR HP1BP3 DDX60 LNPEP MACF1 NUB1 EIF2AK2 MX2	1.05e-07	200	232	10	8ae7cb81de3ffac5acdf3466d4b516d80cac95d3
ToppCell	Tracheal-10x5prime-Epithelial-Epi_airway_ciliated\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	CFAP251 TTC21A TSPAN19 ODAD4 PZP CFAP47 CFAP43 TMEM232 CFAP74 ANKFN1	1.05e-07	200	232	10	31d75c26055177d656df1fbb10b764cebd61e122
ToppCell	Tracheal-10x5prime-Epithelial-Epi_airway_ciliated-Ciliated\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	CFAP251 TTC21A TSPAN19 ODAD4 PZP CFAP47 CFAP43 TMEM232 CFAP74 ANKFN1	1.05e-07	200	232	10	e1dce91c6c531bb212002a14705e496d77ad3490
ToppCell	lung-Ciliated_Epithelia\|lung / shred on tissue and cell subclass	CFAP251 TTC21A TSPAN19 AK9 ODAD4 MUC16 CFAP43 TMEM232 CFAP69	2.44e-07	167	232	9	26cf1cfa58ee74794449a87eb19cd896e1ec8892
ToppCell	systemic_lupus_erythematosus-flare-Lymphocytic_B-plasmablast-female\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	NUGGC KIF4A DCC ALDH1L2 ASPM SCNN1B KIF14 SLC25A4 MUC16	3.62e-07	175	232	9	3b5346fba617292de71963b6175e85a4f182fe30
ToppCell	NS-moderate-d_16-33-Epithelial-Ionocyte\|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	PDE9A BEST3 ITPR2 DST SCG2 SCNN1B SDK2 ANK2 POSTN	4.59e-07	180	232	9	8af8b4af2dc72223ac71fc027e0d4280c5dd81f8
ToppCell	Fetal_29-31_weeks-Epithelial-ciliated_cell-D088\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	CFAP251 TSPAN19 ODAD4 CFAP47 IQCH CFAP43 TMEM232 CFAP74 ANKFN1	4.81e-07	181	232	9	dfce05bd472f67e6e2bb60ebd6fd34f0a9aeeca6
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L5-6_PVALB_STON2\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	SCN7A MITF ASPM NOS1 POSTN EYS PIEZO2 TNFAIP2 MYO16	5.03e-07	182	232	9	a3c5c0eff527c8d3848acda14af8f9e99c69b0de
ToppCell	COVID-19-Epithelial_cells-Airway_ciliated\|COVID-19 / group, cell type (main and fine annotations)	CFAP251 TSPAN19 ODAD4 CFAP47 MUC16 CFAP43 TMEM232 CFAP74 ANKFN1	5.77e-07	185	232	9	18a40f0a338aa398d81384b5159fb80ce8a2020c
ToppCell	T_cells-ISG-high_CD4+_T_cells\|World / Immune cells in Kidney/Urine in Lupus Nephritis	PDE9A ADAR DDX60L DDX60 LIF FAR2 NUB1 EIF2AK2 MX2	6.60e-07	188	232	9	6f8946d4710f6e32c937213f99b790b098b8819c
ToppCell	moderate-Epithelial-Ionocyte\|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	PDE9A BEST3 ITPR2 DST SCG2 SCNN1B SDK2 ANK2 POSTN	6.90e-07	189	232	9	6011b747e27d61d222380a7bffdd921a68e9b657
ToppCell	3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.4\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	TSPAN19 BEST3 ODAD4 ITPR2 GHRH SCG2 SCNN1B ANK2 CFAP43	6.90e-07	189	232	9	cd4746ea6ae48a7dd14a2960d38d9445a738cf2c
ToppCell	Adult-Epithelial-ciliated_cell\|Adult / Lineage, Cell type, age group and donor	CFAP251 TSPAN19 ODAD4 CFAP47 CFAP43 TMEM232 CFAP74 CFAP69 ANKFN1	6.90e-07	189	232	9	b679920f0993e917dd86da082113bfbd85ea1ca5
ToppCell	critical-Epithelial-Ionocyte\|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	BEST3 NRP1 ITPR2 DST SCG2 SCNN1B SDK2 ANK2 POSTN	7.21e-07	190	232	9	05a2c3549b68f49081723bf35db14974274419d5
ToppCell	5'-Airway_Nasal-Immune_Myeloid_mast-Myeloid_Mast/Baso\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ATP8B4 TRO ARMH1 GHRH SCG2 ADAM12 TTLL7 LIF MYO16	7.87e-07	192	232	9	690cf19e9b0b2ada80097c63eae827529aa5b6f3
ToppCell	5'-Airway_Nasal-Immune_Myeloid_mast-Myeloid_Mast/Baso-mast_cell-Mast_cells\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ATP8B4 TRO ARMH1 GHRH SCG2 ADAM12 TTLL7 LIF MYO16	7.87e-07	192	232	9	3d6c4c5847ca1e44fa380403d25af45d5b51ee9b
ToppCell	IPF-Epithelial-Ciliated\|World / Disease state, Lineage and Cell class	CFAP251 TSPAN19 CFAP47 IQCH CFAP43 TMEM232 CFAP74 CFAP69 ANKFN1	7.87e-07	192	232	9	d903bbd6c18e29e2c4cdedeb3fea1fd5ad7baa11
ToppCell	5'-Airway_Nasal-Immune_Myeloid_mast\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ATP8B4 TRO ARMH1 GHRH SCG2 ADAM12 TTLL7 LIF MYO16	7.87e-07	192	232	9	e0412964a3ee1bf3c0ef64f9a6f20f7e7835701e
ToppCell	5'-Airway_Nasal-Immune_Myeloid_mast-Myeloid_Mast/Baso-mast_cell\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ATP8B4 TRO ARMH1 GHRH SCG2 ADAM12 TTLL7 LIF MYO16	7.87e-07	192	232	9	b5871247a5f3e970fa05b33fff21bef9d2ab5741
ToppCell	NS-critical-d_07-13-Epithelial-Ciliated\|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	CFAP251 LRRC49 TSPAN19 CFAP47 CFAP43 TMEM232 CFAP74 CFAP69 ANKFN1	8.58e-07	194	232	9	1ae8a10e508e672e6677f0e3c986ac30d05adeb3
ToppCell	Mild/Remission-B_activate-7\|Mild/Remission / disease group and sub_cluster of B and Plasma cells(res = 0.5)	RIPOR2 USP25 DDX60L DSP DDX60 JMJD1C NUB1 EIF2AK2 MX2	8.58e-07	194	232	9	01c97543972159a9468272da06e7e611e2c21fae
ToppCell	COVID-19-Epithelial-Ciliated_cells\|COVID-19 / Condition, Lineage and Cell class	CFAP251 TSPAN19 ODAD4 CFAP47 MUC16 CFAP43 TMEM232 CFAP74 CFAP69	8.58e-07	194	232	9	43be5fbd51dd58839cb03ca3ddd05a458e1ddb74
ToppCell	B_cells-ISG-high_B_cells\|B_cells / Immune cells in Kidney/Urine in Lupus Nephritis	USP25 DDX60L DSP DDX60 LNPEP ELF1 NUB1 EIF2AK2 MX2	8.96e-07	195	232	9	b64d9e1a8834401b4dc501566546647754ae21fc
ToppCell	Control_saline-Epithelial_airway-airway_epithelial-Ciliated\|Control_saline / Treatment groups by lineage, cell group, cell type	TTC21A TSPAN19 ARMH1 AK9 ODAD4 UMODL1 BBOX1 IQCH CFAP69	8.96e-07	195	232	9	60067b5359174f0d1a8b5748bfc0690762e9e740
ToppCell	saliva-Mild-Moderate_progression_d12-25-Myeloid-Granulocytic-Neutrophil\|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)	RIPOR2 ADAM8 DDX60L DOCK2 JMJD1C LIF ARRB2 ELF1 MX2	9.35e-07	196	232	9	fe8d3f45a64323947c36b127355d5940eb56c0ca
ToppCell	Mild-CD4+_T_activated\|Mild / Disease group and Cell class	RIPOR2 TTC21A CCR4 DDX60L DDX60 ELF1 NUB1 EIF2AK2 MX2	9.35e-07	196	232	9	daa1c3322d81e649161e889e1d78451d2d425d09
ToppCell	Mild-CD8+_T_activated\|World / Disease group and Cell class	ADAR DDX60L TARBP1 DDX60 LNPEP ELF1 NUB1 EIF2AK2 MX2	9.35e-07	196	232	9	79632190e44fcef9d7c11d9b9e37f2ebf0e6e255
ToppCell	saliva-Mild-Moderate_progression_d12-25-Myeloid-Granulocytic\|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)	RIPOR2 ADAM8 DDX60L DOCK2 JMJD1C LIF ARRB2 ELF1 MX2	9.35e-07	196	232	9	526d037bb12d81f1c235c60ddc787fbad0bbad77
ToppCell	LPS_anti-TNF-Mesenchymal_fibroblastic-Fibroblasts-Activated_MatrixFB\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	ABCA1 DST BSN PZP SDK2 ANK2 MACF1 CFAP69 MYO16	9.75e-07	197	232	9	fdb92985f7df0c280b87d3e43c2394e70786a2c7
ToppCell	PSB-critical-LOC-Epithelial-Ciliated\|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	CFAP251 LRRC49 TSPAN19 AK9 CFAP47 CFAP43 TMEM232 CFAP74 CFAP69	9.75e-07	197	232	9	6865f4831eb23794fb88a8649d48d497bbae3f44
ToppCell	3'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.2\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CFAP251 TTC21A AK9 ODAD4 CFAP47 IQCH CFAP43 CFAP74 CFAP69	9.75e-07	197	232	9	74a2c6cb8fcfe53dd9a2b36492a16c58f38e51c9
ToppCell	COVID-19_Mild\|World / Disease group, lineage and cell class	ADAR DDX6 DDX60L DDX60 JMJD1C ELF1 ELF2 EIF2AK2 MX2	9.75e-07	197	232	9	5c33454b10023decd2f5ccda9229b6512659711e
ToppCell	Control-Control-Lymphocyte-T/NK-NK_activated\|Control / Disease, condition lineage and cell class	NUGGC IL18RAP MYLK4 DDX60 UNC45B LNPEP MACF1 EIF2AK2 MX2	1.02e-06	198	232	9	76d5fe4e5bbe6c73a6ca409b80b5c3924e07cab7
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-TAM-MG-TAM-MG_pro-infl_II-G\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	SERPINB9 TLN2 C3 DOCK2 GPR34 NR4A3 SRGAP2 ELF1 MX2	1.06e-06	199	232	9	e245851a5bddf56f7e13a7fb7c5fda2fd275dae3
ToppCell	Bronchus_Control_(B.)-Epithelial-TX-Ciliated\|Bronchus_Control_(B.) / Sample group, Lineage and Cell type	CFAP251 TTC21A TSPAN19 AK9 ODAD4 CFAP47 CFAP43 CFAP74 CFAP69	1.11e-06	200	232	9	6a2ccc71a0cbe04a542c379b28b5006de53981c3
ToppCell	LPS_only-Mesenchymal_fibroblastic-Fibroblasts-MatrixFB\|LPS_only / Treatment groups by lineage, cell group, cell type	ABCA1 PTCH1 NRP1 DST PZP SDK2 ANK2 MACF1 MYO16	1.11e-06	200	232	9	a7ef7022b8efcaedb7319b0b43d8c4e99d788fe2
ToppCell	Parenchymal-10x5prime-Epithelial-Epi_airway_ciliated\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	CFAP251 TSPAN19 ODAD4 PZP CFAP47 CFAP43 TMEM232 CFAP74 ANKFN1	1.11e-06	200	232	9	85c98da55f7cd4ffdf9d309b56c8cc5d43f3c04c
ToppCell	Parenchymal-10x5prime-Epithelial-Epi_airway_ciliated-Ciliated\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	CFAP251 TSPAN19 ODAD4 PZP CFAP47 CFAP43 TMEM232 CFAP74 ANKFN1	1.11e-06	200	232	9	12bc7d95c4166d12487081a76d210b7abe5991b0
ToppCell	COVID-19-COVID-19_Mild-Lymphocyte-T/NK-NK_activated\|COVID-19_Mild / Disease, condition lineage and cell class	PTCH1 USP9Y IL18RAP ADAR DDX60 USP24 LNPEP MACF1 EIF2AK2	1.11e-06	200	232	9	2281debd86e5d92e8fe0397aec9ef670800f7471
ToppCell	Control_saline-Mesenchymal_fibroblastic-Fibroblasts-MatrixFB\|Control_saline / Treatment groups by lineage, cell group, cell type	ABCA1 DCC PTCH1 DST PZP NAALAD2 ANK2 MACF1 MYO16	1.11e-06	200	232	9	bd8cf33502adea320e91ca2af14e1911d88ad374
ToppCell	356C-Fibroblasts-Fibroblast-G-\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	DCC NRP1 DST SCN7A XK PIEZO2 MACF1 CATSPERB	2.02e-06	160	232	8	0293b244c063a62819690bf22bbc2681f8d15252
ToppCell	356C-Fibroblasts-Fibroblast-G\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	DCC NRP1 DST SCN7A XK PIEZO2 MACF1 CATSPERB	2.02e-06	160	232	8	3eaae86fa08f7651021316f8e5811bf48055591e
ToppCell	E18.5-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK-NK-NK_G2M\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	RIPOR2 KIF4A RRM1 IL18RAP CLCN2 BSN GPR34 SLC25A14	2.54e-06	165	232	8	ec16a4979b3f203c9f66ed387a7a17bf3a1d3f86
ToppCell	BALF-PFMC-Severe-critical_progression_d12-22_no-steroids-Myeloid-Macrophage-macrophage,_alveolar-Macro_c3-EREG\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	ABCA1 ITPR2 CCR4 CCRL2 NR4A3 SLC43A3 EDNRB TNFAIP2	3.17e-06	170	232	8	9ac1ef57f14418a5dd2aa16861c3df698c28f5ed
ToppCell	NS-moderate-d_07-13-Epithelial-Ionocyte\|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	PDE9A BEST3 ITPR2 DST SCG2 SCNN1B ANK2 POSTN	4.27e-06	177	232	8	99500aed584f793aaf308f8afbf5d1c6a9b4ee55
ToppCell	T_cells-ISG-high_CD4+_T_cells\|T_cells / Immune cells in Kidney/Urine in Lupus Nephritis	TTC21A DDX60L DDX60 LIF FAR2 NUB1 EIF2AK2 MX2	4.64e-06	179	232	8	af35ef8a7768cee0c2af0590e5bec35cee6a4714
ToppCell	5'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	TTC21A TSPAN19 AK9 CFAP43 TMEM232 CFAP74 CFAP69 ANKFN1	4.64e-06	179	232	8	5e5f1cdf4aa66868d45b74ba91e20e848a3cbaff
ToppCell	5'-Airway_Nasal-Epithelial-Neuro-endocrine/ionocytic-ionocyte\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	BEST3 ITPR2 DST SCG2 SCNN1B ANK2 DSP POSTN	5.03e-06	181	232	8	6aef84616e8d2faf54b7e9e6cd02f33c3066dabc
ToppCell	5'-Airway_Nasal-Epithelial-Neuro-endocrine/ionocytic-ionocyte-Ionocyte-Ionocyte_L.0.7.0.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	BEST3 ITPR2 DST SCG2 SCNN1B ANK2 DSP POSTN	5.03e-06	181	232	8	40df0afcb6848202da54670e84f22d7c3a515d01
ToppCell	5'-Airway_Nasal-Epithelial-Neuro-endocrine/ionocytic-ionocyte-Ionocyte\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	BEST3 ITPR2 DST SCG2 SCNN1B ANK2 DSP POSTN	5.03e-06	181	232	8	2b53a65ca5616a7b9f64232c3e0b7212d1e2f063
ToppCell	5'-Airway_Nasal-Epithelial-Neuro-endocrine/ionocytic\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	BEST3 ITPR2 DST SCG2 SCNN1B ANK2 DSP POSTN	5.03e-06	181	232	8	40d3829ae4aaf81e8616c3499ff8933137fc1cc4
ToppCell	Control-Epithelial_cells-Airway_ciliated\|Control / group, cell type (main and fine annotations)	CFAP251 TSPAN19 ARMH1 CFAP47 CFAP43 TMEM232 CFAP74 ANKFN1	5.24e-06	182	232	8	fb725d10d9ed25dfc6d5bb69cfef78513f7d3e8f
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L5-6_PVALB_STON2\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	SCN7A ASPM NOS1 POSTN EYS PIEZO2 TNFAIP2 MYO16	5.24e-06	182	232	8	08aff7112c9dac0ef5540300516a604782b21169
ToppCell	droplet-Spleen-nan-18m\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CHD2 PXK DDX6 ITPR2 JMJD1C LNPEP MACF1 ELF1	5.24e-06	182	232	8	eeb5dfa4539e9ca5220f26bc2b65717ddcf13b6c
ToppCell	NS-critical-d_07-13-Epithelial-Ionocyte\|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	PDE9A BEST3 DST SCG2 SCNN1B SDK2 ANK2 POSTN	5.46e-06	183	232	8	ba43bca2b45be1008eebd3f033cecb061fb3a966
ToppCell	368C-Lymphocytic-CD4_T-cell-Treg_cell_2\|CD4_T-cell / Donor, Lineage, Cell class and subclass (all cells)	MAP3K5 DHCR24 CCR4 ABCC1 WRN SRGAP2 TFE3 EIF2AK4	5.46e-06	183	232	8	310ad42b2b5d8ddd01d3a12db338f80ac1f5d08e
ToppCell	Adult-Epithelial-ciliated_cell-D175\|Adult / Lineage, Cell type, age group and donor	CFAP251 TSPAN19 ODAD4 CFAP47 CFAP43 TMEM232 CFAP74 ANKFN1	5.91e-06	185	232	8	30f4980dee6cd5959655f8d74049f3bfb5312611
ToppCell	NS-moderate-d_07-13-Epithelial-Ciliated\|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	CFAP251 TSPAN19 CFAP47 CFAP43 TMEM232 CFAP74 CFAP69 ANKFN1	6.15e-06	186	232	8	85787ff207f109ec7e3c0f729ba9bda739c2fdc9
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L5_PVALB_CNTNAP3P2\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	BEST3 SCN7A MITF ASPM POSTN EYS PIEZO2 MYO16	6.39e-06	187	232	8	d413fb4b1531b297af5012a392b88128510c2de8
ToppCell	Fetal_29-31_weeks-Epithelial-ciliated_cell\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	CFAP251 TSPAN19 ODAD4 CFAP47 CFAP43 TMEM232 CFAP74 ANKFN1	6.39e-06	187	232	8	9e10ed56090d82589bc457788282f664b70ace4b
ToppCell	moderate-Epithelial-Ionocyte\|moderate / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	BEST3 ITPR2 DST SCG2 SCNN1B SDK2 ANK2 POSTN	6.39e-06	187	232	8	3e3fe2d5712a0ac477cddefe56705d4b8d8f7eac
ToppCell	Adult-Epithelial-ciliated_cell-D231\|Adult / Lineage, Cell type, age group and donor	CFAP251 TSPAN19 CFAP47 CFAP43 TMEM232 CFAP74 CFAP69 ANKFN1	6.65e-06	188	232	8	34b11f72ca73153d02edcd09b38983ad1a504659
ToppCell	10x5'-GI_small-bowel-Lymphocytic_T_CD4-T_CD4/CD8\|GI_small-bowel / Manually curated celltypes from each tissue	CDK17 CHD2 BIRC6 USP24 JMJD1C EPG5 LNPEP MACF1	6.65e-06	188	232	8	ab9b725d6e0cdab8e9ddda6dee09e14730e9a578
ToppCell	Epithelial-ciliated_cell\|World / Lineage, Cell type, age group and donor	CFAP251 TSPAN19 ODAD4 CFAP47 CFAP43 TMEM232 CFAP74 ANKFN1	6.65e-06	188	232	8	61a459f3fe57e5728efc72637ff2edc2d343492b
ToppCell	5'-Airway_Nasal-Immune_Myeloid_mast-Myeloid_Mast/Baso-mast_cell-Mast_cells-Mast_cells_L.1.4.0.1\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	TRO ARMH1 GHRH SCG2 ADAM12 TTLL7 LIF MYO16	6.91e-06	189	232	8	aba941ba6ce7702418b3f470bde573d123c4aade
ToppCell	Control-Epithelial-Ciliated\|Control / Disease state, Lineage and Cell class	CFAP251 TSPAN19 CFAP47 CFAP43 TMEM232 CFAP74 CFAP69 ANKFN1	6.91e-06	189	232	8	c007fccd08728db3ea99af9da91d67b9b16dabb3
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	KRT80 ITPR3 PTPN3 DST BBOX1 LIF LNPEP TNFAIP2	6.91e-06	189	232	8	aadb7a2de4cbe7f0958651f2739bba430b93f5c1
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	KRT80 ITPR3 PTPN3 DST BBOX1 LIF LNPEP TNFAIP2	6.91e-06	189	232	8	8977f3295b7df7c7474b3f371de90a82ae4bb50c
ToppCell	Fetal_29-31_weeks-Immune-monocyte-D088\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	ATP8B4 ADAM8 PTK2B HAVCR1 SERPINB9 DOCK2 ARRB2 MX2	7.18e-06	190	232	8	ad297172a74a80ed5c10f921e15efd1da0fd2d6b
ToppCell	Children_(3_yrs)-Immune-interstitial_macrophage_(C1Q_positive)\|Children_(3_yrs) / Lineage, Cell type, age group and donor	ABCA1 ATP8B4 NRP1 ITPR2 DOCK2 GPR34 SRGAP2 TNFAIP2	7.18e-06	190	232	8	f573fef3762a30c38cf8fa7f45df0ffbb49dc873
ToppCell	Entopeduncular-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)\|Entopeduncular / BrainAtlas - Mouse McCarroll V32	SYNJ1 SCG2 BSN IQSEC3 L1CAM ZDBF2 LIMK1 CEP170B	7.47e-06	191	232	8	5d24022cec293bc8d9e978ae99a109e660bb8f83
ToppCell	Entopeduncular-Neuronal-Inhibitory\|Entopeduncular / BrainAtlas - Mouse McCarroll V32	SYNJ1 SCG2 BSN IQSEC3 L1CAM ZDBF2 LIMK1 CEP170B	7.47e-06	191	232	8	73dae4cdea86aec62393ad7303dc7375a6b3fc86
ToppCell	human_hepatoblastoma-Inflammatory_Monocytes\|World / Sample and Cell Type and Tumor Cluster (all cells)	ATP8B4 PTK2B MITF DDX60L FNIP2 DOCK2 NR4A3 TNFAIP2	7.47e-06	191	232	8	3b59bfc6c106ae8a3fbcd4a74bd128c485724921
ToppCell	Fetal_29-31_weeks-Mesenchymal-matrix_fibroblast_1_cell-D088\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	ABCA1 NRP1 SDK2 LIF PIEZO2 TNFAIP2 CFAP69 MYO16	7.47e-06	191	232	8	08720998aa55131d7377c4c67c4c935865bd7d79
ToppCell	Control-Myeloid-Macrophage_Alveolar\|Myeloid / Disease state, Lineage and Cell class	ACACB USP25 NRP1 DST PSME4 MITF IQSEC3 RMDN3	7.47e-06	191	232	8	a7bb8aba9c59c037d995a77928cc7b4d5cbb82b9
ToppCell	LPS_only-Stromal_mesenchymal-Matrix_Fibroblast-Activated_MatrixFB\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	PZP SDK2 ANK2 LIF PIEZO2 TNFAIP2 CFAP69 MYO16	7.76e-06	192	232	8	df1545670370fb1010c567cd059c2783eab315f7
ToppCell	facs-Brain_Myeloid-Hippocampus-3m-Myeloid-microglial_cell\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DDX6 DST SCG2 GPR34 USP24 SRGAP2 JMJD1C MACF1	8.06e-06	193	232	8	9c16032bc03df8760ae199e8f19fdafa4c3f1827
ToppCell	Control-Myeloid-Monocyte-derived_macrophages\|Control / group, cell type (main and fine annotations)	ABCA1 ATP8B4 ITPR2 MITF DOCK2 SRGAP2 ARRB2 TNFAIP2	8.06e-06	193	232	8	a6b3bd01e585e2e3fbe9bf693a2e385773123f8e
ToppCell	facs-Brain_Myeloid-Hippocampus-3m\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DDX6 DST SCG2 GPR34 USP24 SRGAP2 JMJD1C MACF1	8.06e-06	193	232	8	a4f91bca5eaa985982d33a528f7566ffde154d47
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	BEST3 PHKA1 SCN7A MITF ASPM POSTN EYS MYO16	8.06e-06	193	232	8	c4b22b62f3cc7bf0ec0eba76e1504c236290bbc9
ToppCell	facs-Brain_Myeloid-Hippocampus-3m-Myeloid-nan\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DDX6 DST SCG2 GPR34 USP24 SRGAP2 JMJD1C MACF1	8.06e-06	193	232	8	b39d7feaac4ff8f7409cd3d15e8f3c6391367275
Drug	Nicardipine hydrochloride [54527-84-3]; Up 200; 7.8uM; MCF7; HT_HG-U133A	RIPOR2 TRO PTCH1 PTK2B CLCN7 GLYR1 NOS1 NAALAD2 ADAM12 STK16 LIMK1 CFAP74 TNFAIP2	1.13e-07	196	231	13	5397_UP
Disease	X-11787 measurement	ALMS1 CLYBL HELLS	2.45e-05	8	227	3	EFO_0021258
Disease	epilepsy (implicated_via_orthology)	KIF4A SCN7A BSN NOS1 ANK2 SLC25A4 MINK1 L1CAM	4.05e-05	163	227	8	DOID:1826 (implicated_via_orthology)
Disease	lymphocyte count	RIPOR2 PIEZO1 GPR87 RRM1 IL18RAP ITPR2 HAVCR1 SERPINB9 PSME4 ALMS1 UMODL1 AP1M1 C3 DDX60L FNIP2 DOCK2 ROCK2 ABCC1 MINK1 SLC43A3 RAB40A JMJD1C ARRB2 DNAH17 ELF1 KCTD2	6.64e-05	1464	227	26	EFO_0004587
Disease	membranous glomerulonephritis (biomarker_via_orthology)	ABCA1 MAP3K5 LRPAP1	1.54e-04	14	227	3	DOID:10976 (biomarker_via_orthology)
Disease	lysosomal storage disease (implicated_via_orthology)	CLCN7 MITF TFE3	2.34e-04	16	227	3	DOID:3211 (implicated_via_orthology)
Disease	WAARDENBURG SYNDROME, TYPE 4A	MITF EDNRB	3.50e-04	4	227	2	C1848519
Disease	alcoholic cardiomyopathy (biomarker_via_orthology)	NOS1 SLC25A4	3.50e-04	4	227	2	DOID:12935 (biomarker_via_orthology)
Disease	hypertension (biomarker_via_orthology)	PTK2B HAVCR1 C3 NOS1 EDNRB POSTN ARRB2 PRKCD	3.96e-04	227	227	8	DOID:10763 (biomarker_via_orthology)
Disease	cortical thickness	RIPOR2 LRRC49 RABGAP1 PTCH1 BBS9 PXK NRP1 UMODL1 GLYR1 MITF FNIP2 SRGAP2 ADAM12 JMJD1C HHIP FAR2 CLYBL MACF1 ANKFN1 MYO16	4.11e-04	1113	227	20	EFO_0004840
Disease	Cis-4-decenoyl carnitine measurement	FNIP2 ABCC1	5.80e-04	5	227	2	EFO_0022091
Disease	Gait, Unsteady	DDX6 L1CAM	5.80e-04	5	227	2	C0231686
Disease	Waardenburg Syndrome Type 2	MITF EDNRB	5.80e-04	5	227	2	C2700265
Disease	Waardenburg syndrome (is_implicated_in)	MITF EDNRB	5.80e-04	5	227	2	DOID:9258 (is_implicated_in)
Disease	portal hypertension (is_marker_for)	ARRB2 PRKCD	8.66e-04	6	227	2	DOID:10762 (is_marker_for)
Disease	Waardenburg Syndrome	MITF EDNRB	8.66e-04	6	227	2	C3266898
Disease	beta-citrylglutamate measurement	NAALAD2 JMJD1C	1.21e-03	7	227	2	EFO_0800060
Disease	pulmonary venoocclusive disease (biomarker_via_orthology)	EIF2AK4 EIF2AK2	1.21e-03	7	227	2	DOID:5453 (biomarker_via_orthology)
Disease	osteopetrosis (implicated_via_orthology)	CLCN7 MITF	1.21e-03	7	227	2	DOID:13533 (implicated_via_orthology)
Disease	APOE carrier status, dementia	RIPOR2 NADSYN1 FAR2 CLYBL	1.34e-03	62	227	4	EFO_0007659, MONDO_0001627
Disease	basal cell carcinoma (is_marker_for)	PTCH1 XRCC6	1.60e-03	8	227	2	DOID:2513 (is_marker_for)
Disease	cis-4-decenoylcarnitine (C10:1) measurement	ABCC1 ASB17	1.60e-03	8	227	2	EFO_0800311
Disease	cholesteryl esters to total lipids in large LDL percentage	ABCA1 HAVCR1 JMJD1C	1.72e-03	31	227	3	EFO_0022249
Disease	very low density lipoprotein cholesterol measurement, phospholipids:total lipids ratio	ABCA1 ACACB BANF2 HAVCR1 COPB1 USP24 JMJD1C MACF1	1.96e-03	291	227	8	EFO_0008317, EFO_0020946
Disease	nephronophthisis (implicated_via_orthology)	TTC21A CNTRL	2.05e-03	9	227	2	DOID:12712 (implicated_via_orthology)
Disease	underweight body mass index status	DCC ANK2	2.05e-03	9	227	2	EFO_0005936
Disease	octanoylcarnitine measurement	FNIP2 ABCC1	2.05e-03	9	227	2	EFO_0021042
Disease	membranous glomerulonephritis (implicated_via_orthology)	C3 LRPAP1	2.05e-03	9	227	2	DOID:10976 (implicated_via_orthology)
Disease	platelet-to-lymphocyte ratio	CFAP251 RIPOR2 ITPR3 AP1M1 MINK1 CCRL2 ATF6B JMJD1C FAR2	2.11e-03	363	227	9	EFO_0008446
Disease	Cleft palate	PTCH1 SCNN1B VIRMA LRPAP1	2.21e-03	71	227	4	HP_0000175
Disease	brain ischemia (implicated_via_orthology)	PTK2B NOS1 PRKCD	2.45e-03	35	227	3	DOID:2316 (implicated_via_orthology)
Disease	white matter hyperintensity measurement	DCC OR2K2 TLN2 TARBP1 ABCC1 ANK2 CWC22 CATSPERB	2.46e-03	302	227	8	EFO_0005665
Disease	interventricular septum thickness	ITPR2 MITF	2.55e-03	10	227	2	EFO_0009287
Disease	coffee consumption measurement	BIRC6 SLC25A17 FNIP2 OR5M8 RANBP17 EYS	2.93e-03	182	227	6	EFO_0006781
Disease	N-acetylhistidine measurement	ALMS1 NAT16	3.10e-03	11	227	2	EFO_0800022
Disease	Myoclonic Astatic Epilepsy	CHD2 STXBP1	3.10e-03	11	227	2	C0393702
Disease	venous thromboembolism	CDK17 NUGGC TSPAN19 ITPR3 SERPINB9 CCR4 ABCC1 ANK2 PIEZO2 CATSPERB	3.15e-03	460	227	10	EFO_0004286
Disease	Colorectal Carcinoma	ABCA1 GPR87 DCC SCNN1B PAN2 PZP ABCC1 ANK2 WRN POSTN GMCL2 HHIP ABCE1	3.26e-03	702	227	13	C0009402
Disease	Alzheimer's disease (is_implicated_in)	ABCA1 C3 NOS1 LRPAP1 EIF2AK2	3.62e-03	132	227	5	DOID:10652 (is_implicated_in)
Disease	autosomal dominant cerebellar ataxia (implicated_via_orthology)	ITPR2 ITPR3	3.70e-03	12	227	2	DOID:1441 (implicated_via_orthology)
Disease	Behavior Disorders	NOS1 XK	3.70e-03	12	227	2	C0004930
Disease	Mental disorders	NOS1 XK	3.70e-03	12	227	2	C0004936
Disease	Abruptio Placentae	DOCK2 ADAM12	3.70e-03	12	227	2	EFO_1001754
Disease	decanoylcarnitine measurement	ABCC1 ASB17	3.70e-03	12	227	2	EFO_0021039
Disease	Mental Disorders, Severe	NOS1 XK	3.70e-03	12	227	2	C4046029
Disease	Diagnosis, Psychiatric	NOS1 XK	3.70e-03	12	227	2	C0376338
Disease	smoking cessation	DCC BIRC6 ITPR3 STXBP1 ALMS1 BSN FNIP2 JMJD1C	3.84e-03	325	227	8	EFO_0004319
Disease	congestive heart failure (implicated_via_orthology)	PDE9A POSTN ARRB1	3.86e-03	41	227	3	DOID:6000 (implicated_via_orthology)
Disease	mitochondrial DNA measurement	CFAP251 TTC21A RRM1 ITPR3 PTK2B COPB1 JMJD1C FAR2	4.06e-03	328	227	8	EFO_0006312
Disease	free cholesterol measurement, low density lipoprotein cholesterol measurement	ABCA1 BANF2 HAVCR1 USP24 JMJD1C	4.24e-03	137	227	5	EFO_0004611, EFO_0008591
Disease	Drug-Induced Liver Disease	ADAM8 MAP3K5 HAVCR1 ALDH1L2 PAN2 C3 PZP ABCC1 PRKCD	4.27e-03	404	227	9	C0860207
Disease	Drug-Induced Acute Liver Injury	ADAM8 MAP3K5 HAVCR1 ALDH1L2 PAN2 C3 PZP ABCC1 PRKCD	4.27e-03	404	227	9	C3658290
Disease	Hepatitis, Toxic	ADAM8 MAP3K5 HAVCR1 ALDH1L2 PAN2 C3 PZP ABCC1 PRKCD	4.27e-03	404	227	9	C0019193
Disease	Chemically-Induced Liver Toxicity	ADAM8 MAP3K5 HAVCR1 ALDH1L2 PAN2 C3 PZP ABCC1 PRKCD	4.27e-03	404	227	9	C4279912
Disease	Chemical and Drug Induced Liver Injury	ADAM8 MAP3K5 HAVCR1 ALDH1L2 PAN2 C3 PZP ABCC1 PRKCD	4.27e-03	404	227	9	C4277682
Disease	Hepatitis, Drug-Induced	ADAM8 MAP3K5 HAVCR1 ALDH1L2 PAN2 C3 PZP ABCC1 PRKCD	4.27e-03	404	227	9	C1262760
Disease	ventricular enlargement measurement	ABCC1 CATSPERB	4.35e-03	13	227	2	EFO_0010570
Disease	developmental and epileptic encephalopathy (implicated_via_orthology)	STXBP1 MX2	4.35e-03	13	227	2	DOID:0112202 (implicated_via_orthology)
Disease	insulin metabolic clearance rate measurement, glucose homeostasis measurement	DCC SLC43A3	5.05e-03	14	227	2	EFO_0006830, EFO_0006896
Disease	Heart Diseases	BSN ABCC1 UNC45B	5.35e-03	46	227	3	C0018799
Disease	diastolic blood pressure, systolic blood pressure	ATP8B4 RIPOR2 LRRC49 PSMD1 ALMS1 TLN2 NAALAD2 ANK2 COPS3 PIEZO2 CLYBL PTCD2	6.00e-03	670	227	12	EFO_0006335, EFO_0006336
Disease	schizophrenia, anorexia nervosa	FTCDNL1 ALMS1 PPP1R13B	6.02e-03	48	227	3	MONDO_0005090, MONDO_0005351
Disease	cholesteryl ester measurement, intermediate density lipoprotein measurement	ABCA1 BANF2 HAVCR1 JMJD1C	6.06e-03	94	227	4	EFO_0008595, EFO_0010351
Disease	cognitive function measurement, self reported educational attainment	DCC PTCH1 BIRC6 CLCN2 ALMS1 BSN WRN JMJD1C	6.46e-03	355	227	8	EFO_0004784, EFO_0008354
Disease	lipid measurement, intermediate density lipoprotein measurement	ABCA1 BANF2 HAVCR1 JMJD1C	6.53e-03	96	227	4	EFO_0004529, EFO_0008595
Disease	interferon gamma measurement, platelet-derived growth factor BB measurement, interleukin 4 measurement, interleukin 10 measurement, stromal cell-derived factor 1 alpha measurement, interleukin-6 measurement, interleukin 12 measurement, interleukin 17 measurement, vascular endothelial growth factor measurement, fibroblast growth factor basic measurement, granulocyte colony-stimulating factor measurement	SCG2 JMJD1C	6.59e-03	16	227	2	EFO_0004750, EFO_0004753, EFO_0004762, EFO_0004810, EFO_0008130, EFO_0008142, EFO_0008165, EFO_0008174, EFO_0008184, EFO_0008264, EFO_0008293
Disease	primary autosomal recessive microcephaly (is_implicated_in)	ASPM KIF14	6.59e-03	16	227	2	DOID:0070296 (is_implicated_in)
Disease	total cholesterol measurement, intermediate density lipoprotein measurement	ABCA1 BANF2 HAVCR1 JMJD1C	7.26e-03	99	227	4	EFO_0004574, EFO_0008595
Disease	phospholipid measurement, intermediate density lipoprotein measurement	ABCA1 BANF2 HAVCR1 JMJD1C	7.26e-03	99	227	4	EFO_0004639, EFO_0008595
Disease	Antibody Deficiency Syndrome	C3 EPG5	7.43e-03	17	227	2	C0003257
Disease	glutarylcarnitine (C5-DC) measurement	FNIP2 ABCC1	7.43e-03	17	227	2	EFO_0800030
Disease	MHPG measurement, 5-HIAA measurement	ADAM12 PIEZO2	7.43e-03	17	227	2	EFO_0005132, EFO_0005133
Disease	Influenza	DDX60 EIF2AK2 MX2	7.53e-03	52	227	3	C0021400
Disease	serum IgG glycosylation measurement	BANF2 CHD2 ITGB3 UMODL1 ALDH1L2 DOCK2 WRN EYS ANKFN1 CEP170B	7.61e-03	523	227	10	EFO_0005193

Protein segments in the cluster

Peptide	Gene	Start	Entry
VGLYRQKSNLKVVLT	UMODL1	1141	Q5DID0
RLLLTGVQKRYFEKL	BEST3	51	Q8N1M1
RLPQLGEKVLVKAAY	CCAR2	86	Q8N163
NYVTKRQSLKLLGEL	CAB39L	221	Q9H9S4
LILRLKLHKNDYGIQ	EPG5	971	Q9HCE0
RVELLAKKISQLGYS	DDX6	346	P26196
RRTKLKGNILLDYTL	CFAP43	101	Q8NDM7
LILVKYKGLKRVENI	CCRL2	61	O00421
KLEVLNLSYNLIGKI	CNTRL	126	Q7Z7A1
KDLLYKQLSGRLQLV	CNTRL	491	Q7Z7A1
ILAKVEGQRLVYQFK	ELF1	276	P32519
GLTYIKIQLVKAEVA	BIRC6	3261	Q9NR09
YIKDLNILGRDLSKT	CTDSPL2	386	Q05D32
IDLGNSYVLKAKVIR	CATSPERB	736	Q9H7T0
KYILVSLILLGKVQQ	COPS3	226	Q9UNS2
GIKLQVLINLGLVYK	EIF2AK4	1306	Q9P2K8
RVYFKNKLKLALIGQ	ALDH1L2	16	Q3SY69
GLESKRLRKYLFQIL	CDKL3	96	Q8IVW4
IKDLVGYDVRQALLK	ARMH1	246	Q6PIY5
FLLIILSYIKIGKNL	GPR34	231	Q9UPC5
KLGVSIQNLVKVYRD	ABCA1	896	O95477
LYKKRVTNQLLGRKV	ALMS1	4151	Q8TCU4
VYVLDLKGKVLICRN	AP1M1	6	Q9BXS5
LELIKKGYTQQLAFR	C3	1046	P01024
IENKRKVLGKALYLI	BTBD3	306	Q9Y2F9
LAAGFVVYLKRKTLI	ADAM12	721	O43184
IIGNSTLLRIIYKNK	EDNRB	116	P24530
GNSVVVLVLFKYKRL	CCR4	56	P51679
RAVLRGNLEKLKYLL	ANKRD36B	26	Q8N2N9
LVKKYRNAVTLAIGD	ATP8B4	801	Q8TF62
LYQKLNFRVVLVGLE	ADAM8	236	P78325
LIRNLNVILAKYGLD	LRPAP1	111	P30533
QKYVTLKLNDVIRFG	CEP170B	76	Q9Y4F5
ALIIQKYIRAREAGK	ASPM	3056	Q8IZT6
LLELLQIYREKPGNK	ASPM	3346	Q8IZT6
SELRERLYGKKIQLN	PPP1R13B	311	Q96KQ4
NREILGIIVSYKVKV	ARRB1	311	P49407
ANKEVLGILVSYRVK	ARRB2	311	P32121
YLVFINRDKVGLQIL	CFAP251	861	Q8TBY9
DILYARQKIVVIAKA	CLYBL	221	Q8N0X4
YLLKQALKRELNRGV	HP1BP3	201	Q5SSJ5
KYLGNLIKGVKRILE	RANBP17	301	Q9H2T7
LNDLSVGYILLKKLV	RANBP17	616	Q9H2T7
YKTTTILLDGQRVKL	RAB40A	51	Q8WXH6
YKTTTILLDGQRVKL	RAB40AL	51	P0C0E4
QLTQEIKAKAVGYLI	PZP	1001	P20742
QLDIKTGNLLLYEKL	PCDHB5	76	Q9Y5E4
IKRIKNLIRGTEAYI	IQCH	561	Q86VS3
ISNIIVLGIFIKYKE	RRH	41	O14718
VLIQFEQLYRKKPGL	PTPN3	646	P26045
EGNTLRKILLNRYFK	ITPR2	1691	Q14571
EYKGKLQVFLRTTLR	ITPR3	256	Q14573
NCGKEKVLFLRLYLL	NUB1	331	Q9Y5A7
YSFILKVVLRIKAEG	OR56A4	221	Q8NGH8
RVGLVLLLQDYSVKK	RADX	291	Q6NSI4
VQSKKNILVDYGLRR	ACACB	1446	O00763
AKYGSLDVAKLLLQR	ANK2	571	Q01484
LRQGIDKKIVIYVQQ	RABGAP1	321	Q9Y3P9
DLKVIYILVRPKAGQ	FAR2	36	Q96K12
LLRDIQDKVTTLYKG	MUC16	14226	Q8WXI7
YLKLRFLIDIGVKFV	PAN2	1066	Q504Q3
GEEVIQLRSKKYSLL	DCC	276	P43146
LRQEVKKLGGYLQLF	KIF14	1341	Q15058
KLVRNIYKRKGTLQI	HELLS	311	Q9NRZ9
QLKEKRGVVLLYILL	IL18RAP	351	O95256
IASKRIKYLGIQLTR	nan	761	O00370
IKYLGIQLTRDVKDL	nan	766	O00370
DKGLISRIYNELKQI	nan	1046	O00370
ENILKLLKIRQYGIT	EYS	1696	Q5T1H1
IYARKGSVLQSIEKI	LRIF1	496	Q5T3J3
IIDFGKIIIYTNNLK	GRXCR2	116	A6NFK2
SKGIIYRDLKLDNVL	PRKCD	466	Q05655
LAAKYGQTNLVKLLL	MYO16	261	Q9Y6X6
GVITNYLLEKSRLVK	MYO1A	176	Q9UBC5
QLLKALKLERDTTGY	MYO1A	211	Q9UBC5
YLKAELSRQLEGILK	DST	4811	Q03001
IRYISGILRKKVEAL	PHKA1	826	P46020
QLLGKYKQIIAVLAQ	LIF	186	P15018
NIFKILLQYGILERE	ASB17	161	Q8WXJ9
VNKKLRQRLLEEYGV	JMJD1C	2431	Q15652
YLFTLQIKKDLALGR	FRMD7	96	Q6ZUT3
NVKLALDIEIATYRK	KRT80	371	Q6KB66
LKYLELGITQRKESL	BSN	2976	Q9UPA5
ELILKRLILNFRKGY	CWC22	231	Q9HCG8
KEKQLVEILFRKGYL	DDX60	1271	Q8IY21
KLVLVLANLFGRKYI	DDX60L	1466	Q5H9U9
VIGLAVALVLYIRKK	C3orf18	71	Q9UK00
IVVENLAGLKYRVIK	CLCN7	146	P51798
QLLNYLKADRLGKSI	PDCD2	296	Q16342
LYKGLEAKLLQTVLT	SLC25A17	266	O43808
SIKTKQIQYGIIRLL	OR51B2	291	Q9Y5P1
KAIYLDIDGRIQKVI	PDE9A	11	O76083
KKYRLITKQGILLVR	NAT16	171	Q8N8M0
LTKIALRYVALVQEK	COPB1	561	P53618
DLAGKYRQILEKAIQ	COPS4	21	Q9BT78
KYIQKDLRLAIALGD	GLYR1	501	Q49A26
KQIKIIDFGLARRYK	MYLK4	241	Q86YV6
VLLIQEKLDGIKTRY	MACF1	1656	O94854
ISILGDARKKQFRYL	LRRC49	561	Q8IUZ0
LGKVPLKRAFDLINY	LNPEP	741	Q9UIQ6
LAKDQKYRIQRGALI	L1CAM	376	P32004
LGQLKIIKDFYLLGR	TUBGCP4	351	Q9UGJ1
RFNYVVKLLQLIAKS	FBXO25	121	Q8TCJ0
LRYIQFETLVSGIKK	FMO6P	101	O60774
EYLRSKGLQEKAVLL	JRKL	276	Q9Y4A0
VYKGRSKLTENLVAL	CDK17	206	Q00537
RAGNEYLIFQKIIKL	PDPK2P	256	Q6A1A2
FIYTIRNKEVKGALR	OR6X1	286	Q8NH79
LVVGIYERIQQKELK	IQSEC3	826	Q9UPP2
GIIDILQSYRFVKKL	PIP5K1A	401	Q99755
FLGLISIDRYLKVVK	GPR87	131	Q9BY21
LILRLQEYFEKQGVK	BBS9	616	Q3SYG4
EKQRLLVLSKGLQEY	NOS1	1126	P29475
ALKNKELRQGLYKVL	OR56B2P	301	Q8NGI1
GRVLLHKSLKLYQVI	NRP1	766	O14786
YLDVKQRLKAAITIR	ABCE1	246	P61221
EVLGRFVIYKKSVLN	ADAM30	271	Q9UKF2
KIGTYQSLKRLFIER	SLC25A30	86	Q5SVS4
VLLLLGLASYIRKKQ	C2orf92	206	A0A1B0GVN3
IYLALQKRQILSEGK	CASD1	616	Q96PB1
ALIYIIGLIADRKFQ	DOCK2	676	Q92608
NKVRKIGELVRYLNT	ADAR	711	P55265
LAINLVTKGINKAYI	BANF2	31	Q9H503
AYERRFNKKLITGII	CAPN7	301	Q9Y6W3
KALVAVLREVKYLNF	DNAH17	676	Q9UFH2
LYQNLLAKKRTELVA	DNAH17	3026	Q9UFH2
KAIRLGQKSYLDVIE	DNAH17	3461	Q9UFH2
YIGLINRIAQKKRLT	EIF2AK2	101	P19525
QGKQLQTRADYLLKL	CHD2	1306	O14647
VVGKQKDLVQRILYV	FNIP2	506	Q9P278
LKLTQGETLRKLYEQ	DHCR24	366	Q15392
KRIAYSLLGLKDQVN	EPHA2	956	P29317
YGQIKELNEKITRLT	DSP	1101	P15924
NIGIKGLIFDRKKVY	BBOX1	61	O75936
KQILYLLEKFVAVLG	DDX12P	461	Q92771
KDVLLRLLQKYGEVL	DNAJC17	191	Q9NVM6
ILAKVEGQRLVYQFK	ELF2	276	Q15723
VLQLIVDAYGKIRSK	ITGB3	366	P05106
ALKYLIGELVSSKIQ	KIF4A	866	O95239
GKVIELRIEALKNYQ	CCDC196	196	A0A1B0GTZ2
GRKYIVENIAKAALL	FTCDNL1	21	E5RQL4
LKAKRITVSQLLEYG	CCDC168	2806	Q8NDH2
YVVVVKNVGLTLRKL	PTK2B	906	Q14289
VGLKDRQQLYKLIIS	CSTF1	6	Q05048
ENIRAKIYAILGKLD	CFAP69	716	A5D8W1
LQKDLKRYLTRKIGF	SEC24B	906	O95487
LYVLALLKQKAFRTG	SEC24B	1076	O95487
LLVFVLIIRGQSKKY	SDK2	1946	Q58EX2
TLSRKGIVKLNIYFQ	SCNN1B	486	P51168
IILSNKKIGQLIYVA	CFAP47	2101	Q6ZTR5
LLQLRGDVKETYKVI	CFAP74	1561	Q9C0B2
YQETIKKGDLLLNRV	PSMD6	366	Q15008
LGAKRYLLTDNVVKL	PTCD2	41	Q8WV60
ILNYLRHGKLIITKE	KCTD2	131	Q14681
NKKVGLLYRLLQASI	P2RX5	26	Q93086
LLITISGKRNKLRVY	MINK1	1071	Q8N4C8
LIYTLRNKVVRGAVK	OR2J3	291	O76001
AQKIDKIISLLYGVL	OR2K2	266	Q8NGT1
KTAVIGAVYRKALVI	ABCC1	396	P33527
ILNDIRKARNLYTGK	MAP3K5	276	Q99683
RKICTLGLQRIFYLK	NR4A3	591	Q92570
YLNLKRAAILTKLQG	AK9	286	Q5TCS8
KREGFQLLLNNKLVY	RMDN3	256	Q96TC7
GVKYLINRLLALIEK	NUGGC	81	Q68CJ6
GTVIIDNKRYLFIQK	STK16	11	O75716
FRTLKNLYGKQIIVN	SYNJ1	286	O43426
KLIFYDLRGEGVKLQ	KARS1	141	Q15046
LQKELQRYLTRKIGF	SEC24A	731	O95486
IQKVLFRQQLYGIKT	SLC25A51	51	Q9H1U9
LKSEKTVRQLLGELY	ODAD4	181	Q96NG3
LRKKYGVQFILDALR	NBEAL2	1056	Q6ZNJ1
IELYRLFGIKQIVIS	GIN1	216	Q9NXP7
RTTGYQILILKKDQE	GMCL2	471	Q8NEA9
VLLALLGVIIAKKYF	HAVCR1	306	Q96D42
KYKQAIGIALETRRL	PSMD1	146	Q99460
VLAYKLLVQTGSRDK	PTCH1	881	Q13635
DVSKVIAYLKRLVNA	SCG2	306	P13521
AVFLIIKLLYEKGIS	SLC43A3	171	Q8NBI5
LIIYSLRNKNVKEAL	OR5M8	286	Q8NGP6
NVLTDIKLGKYRIVY	WRN	626	Q14191
VIVVGYESLKKLSLR	SLC25A44	291	Q96H78
IQKVLFRQQLYGIKT	SLC25A52	51	Q3SY17
RKSLKIIYINSIGEL	PRAMEF2	196	O60811
RIILLYIFLKNGITE	STXBP1	406	P61764
RKNAIVVLIPKYGLE	DIS3	856	Q9Y2L1
YRKVLGQLSARKLLQ	GHRH	41	P01286
RLFILEKEGYVKILT	HHIP	241	Q96QV1
RLGVLYDLDKQIKTI	RIPOR2	111	Q9Y4F9
IIKIFKSDGLRGLYQ	SLC25A4	161	P12235
LYRLQLSKAKGIVTI	ACSM1	151	Q08AH1
NKFVKTLKRGLYIAV	ANKFN1	431	Q8N957
KKEYLQGLEARLQAV	ATF6B	346	Q99941
VFRRYLNKILIEAGK	CLCC1	96	Q96S66
LRGVVLKEYLTLKTF	CLCN2	171	P51788
KNRIAIYELLFKEGV	RPS10	6	P46783
KIGIYQSLKRLFVER	SLC25A14	121	O95258
LAKLLQERGISAKVY	TRAK2	741	O60296
IYVVDNGLRKILKVV	UNC45B	321	Q8IWX7
KDVIVGKIYFLLVRI	VPS26B	186	Q4G0F5
LKLNKDIVISVGIYN	XRCC6	261	P12956
VKEYIIQLSKGRLVL	TNFAIP2	526	Q03169
YKNLIILAGSELFKR	ZNF846	41	Q147U1
KVEGVYTNARKQLLI	USP45	661	Q70EL2
INNRLDLVKFYISKG	ZDHHC13	91	Q8IUH4
GTILKASVDYIRKLQ	MITF	351	O75030
GTILKASVDYIRKLQ	TFE3	386	P19532
ETRLVLVNAIYFKGK	SERPINB9	156	P50453
IQELYRSLVQKGLVK	SMTNL1	476	A8MU46
VAILQERANKLVKYL	TRO	441	Q12816
LERSYLLKINGKVAE	RRM1	151	P23921
EKIAKYGIRNSLLIA	RRM1	586	P23921
VEIKLAKIGYLVFLR	TMEM232	161	C9JQI7
VGYKGTQLKALLILE	FAM20B	101	O75063
EYLEGRNLITKLQAK	SRGAP2	456	O75044
YLRKTVLGKVIFQVI	PIEZO2	2251	Q9H5I5
VLQSAIKLEYARLVK	USP25	776	Q9UHP3
QGIKDSLQKVILRRY	ZNF716	101	A6NP11
FKIINRKKDYIILGE	ZDBF2	1601	Q9HCK1
KTYGRQILEVLKFLH	PXK	266	Q7Z7A4
FLNRYEKIVKKIRGL	ROCK2	71	O75116
RGAYLNALKIAKLLL	USP9Y	1146	O00507
GYLFILKNQVKEALL	TTC21A	341	Q8NDW8
VDGRKLLLYREQLVK	PSME4	686	Q14997
LKRQGAQLYVEKLEL	USP24	806	Q9UPU5
IVGKIYFLLVRIKIQ	VPS26A	191	O75436
RLKSNYQLGELVKVE	XPO7	336	Q9UIA9
ISQLIAGYIDIILKK	TLN2	391	Q9Y4G6
AVARIKKGINYVLLK	SCN7A	751	Q01118
LYLRKTVLGKLAFQV	PIEZO1	2021	Q92508
LGLKLQKFLVTYISL	TARBP1	446	Q13395
IQFETLGKKGKYIRL	TRPM8	106	Q7Z2W7
GNDQLLEILNKLIKY	POSTN	636	Q15063
KLIKYIQIKFVRGST	POSTN	646	Q15063
QEVKYLFTGLKLRLQ	USP14	281	P54578
NEKSGYQKLLELILL	VIRMA	526	Q69YN4
KTIIIKYFLNLINGA	TSPAN19	6	P0C672
ELFLGLKIGELQKLY	ZFC3H1	1081	O60293
VYGALRCNILAIKIK	XK	181	P51811
ALLVKYQGLVVKQLV	UFL1	726	O94874
KIDYDVKRGVLLNAL	TTLL7	361	Q6ZT98
VLKFIGVLYKDKRLN	LIMK1	396	P53667
IGLQIKALIKKYIQR	MX2	241	P20592
KKQLSVAQLRGALVY	NAALAD2	561	Q9Y3Q0
ILKSIEIAKNRGARY	NADSYN1	26	Q6IA69
NEAAIKNVYLKVRGL	MYOM1	1091	P52179