Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionbenzodiazepine receptor binding

RIMBP3 RIMBP3C RIMBP3B

2.32e-0651243GO:0030156
GeneOntologyMolecularFunctionmedium-chain fatty acid omega-hydroxylase activity

CYP4A11 CYP4A22

3.83e-0521242GO:0140981
GeneOntologyMolecularFunction16-hydroxypalmitate dehydrogenase activity

CYP4A11 CYP4A22

3.83e-0521242GO:0103002
GeneOntologyMolecularFunctiondinitrosyl-iron complex binding

GSTA1 GSTA2

3.78e-0451242GO:0035731
GeneOntologyMolecularFunctionphosphatidylinositol-5-phosphate binding

WASHC2C OBSCN WASHC2A

3.78e-04231243GO:0010314
GeneOntologyMolecularFunctionlipid binding

TRPV1 CYP26B1 WASHC2C CYP4A11 OBSCN SNX16 ZCCHC2 CPNE5 WASHC2A OPHN1 CYP4A22 GSTA1 GSTA2 MYOF CPNE1 SNX9

4.10e-0498812416GO:0008289
GeneOntologyMolecularFunctionmonocarboxylic acid binding

CYP26B1 CYP4A11 CYP4A22 GSTA1 GSTA2

5.46e-041071245GO:0033293
GeneOntologyMolecularFunctionphospholipid binding

TRPV1 WASHC2C OBSCN SNX16 ZCCHC2 CPNE5 WASHC2A OPHN1 MYOF CPNE1 SNX9

6.22e-0454812411GO:0005543
GeneOntologyMolecularFunctionsteroid delta-isomerase activity

GSTA1 GSTA2

7.87e-0471242GO:0004769
GeneOntologyMolecularFunctionleukotriene-B4 20-monooxygenase activity

CYP4A11 CYP4A22

7.87e-0471242GO:0050051
GeneOntologyMolecularFunctionalkane 1-monooxygenase activity

CYP4A11 CYP4A22

7.87e-0471242GO:0018685
GeneOntologyMolecularFunctionfatty acid binding

CYP4A11 CYP4A22 GSTA1 GSTA2

8.97e-04691244GO:0005504
GeneOntologyMolecularFunctionphosphatidylinositol-3,4-bisphosphate binding

WASHC2C OBSCN WASHC2A

1.32e-03351243GO:0043325
GeneOntologyMolecularFunctionaromatase activity

CYP4A11 CYP4B1 CYP4A22

1.32e-03351243GO:0070330
GeneOntologyMolecularFunctionphosphatidylinositol-4-phosphate binding

WASHC2C OBSCN WASHC2A

1.44e-03361243GO:0070273
GeneOntologyMolecularFunctionarachidonate omega-hydroxylase activity

CYP4A11 CYP4A22

1.67e-03101242GO:0052869
GeneOntologyMolecularFunctionfatty acid omega-hydroxylase activity

CYP4A11 CYP4A22

1.67e-03101242GO:0120250
GeneOntologyMolecularFunctionretromer complex binding

WASHC2C WASHC2A

1.67e-03101242GO:1905394
GeneOntologyMolecularFunctionlong-chain fatty acid omega-hydroxylase activity

CYP4A11 CYP4A22

1.67e-03101242GO:0102033
DomainFAM21

WASHC2C WASHC2A

4.23e-0521222IPR027308
DomainATPase_dyneun-rel_AAA

DNAH3 MDN1 DNAH6

9.39e-05141223IPR011704
DomainAAA_5

DNAH3 MDN1 DNAH6

9.39e-05141223PF07728
DomainCAP-ZIP_m

WASHC2C WASHC2A

1.26e-0431222PF15255
DomainFAM21/CAPZIP

WASHC2C WASHC2A

1.26e-0431222IPR029341
DomainCyt_P450_CS

CYP26B1 CYP4A11 CYP4B1 CYP4A22

3.96e-04531224IPR017972
DomainGST_alpha

GSTA1 GSTA2

4.18e-0451222IPR003080
DomainCYTOCHROME_P450

CYP26B1 CYP4A11 CYP4B1 CYP4A22

5.24e-04571224PS00086
Domain-

CYP26B1 CYP4A11 CYP4B1 CYP4A22

5.60e-045812241.10.630.10
Domainp450

CYP26B1 CYP4A11 CYP4B1 CYP4A22

5.60e-04581224PF00067
DomainCyt_P450

CYP26B1 CYP4A11 CYP4B1 CYP4A22

6.37e-04601224IPR001128
DomainCopine

CPNE5 CPNE1

1.48e-0391222PF07002
DomainCopine

CPNE5 CPNE1

1.48e-0391222IPR010734
Domain-

EWSR1 SHARPIN

1.84e-031012224.10.1060.10
DomainFN3

IL13RA1 OBSCN RIMBP3 PTPRD RIMBP3C RIMBP3B

1.97e-031991226PS50853
DomainGlutathione-S-Trfase_C-like

GSTA1 GSTA2 MTX3

2.09e-03391223IPR010987
Domain-

GSTA1 GSTA2 MTX3

2.09e-033912231.20.1050.10
DomainPDZ

SHANK1 RHPN1 AHNAK SIPA1L1 AHNAK2

2.34e-031411225PF00595
DomainSH3_2

SHANK1 RIMBP3 RIMBP3C RIMBP3B

2.44e-03861224PF07653
DomainSH3_2

SHANK1 RIMBP3 RIMBP3C RIMBP3B

2.44e-03861224IPR011511
DomainFN3_dom

IL13RA1 OBSCN RIMBP3 PTPRD RIMBP3C RIMBP3B

2.52e-032091226IPR003961
DomainPP2C_BS

PPM1E PPM1F

2.68e-03121222IPR000222
DomainPDZ

SHANK1 RHPN1 AHNAK SIPA1L1 AHNAK2

2.88e-031481225SM00228
DomainSH3

SHANK1 OBSCN RIMBP3 RIMBP3C RIMBP3B SNX9

2.97e-032161226SM00326
DomainSH3

SHANK1 OBSCN RIMBP3 RIMBP3C RIMBP3B SNX9

2.97e-032161226PS50002
Domain-

SHANK1 RHPN1 AHNAK SIPA1L1 AHNAK2

3.05e-0315012252.30.42.10
DomainPDZ

SHANK1 RHPN1 AHNAK SIPA1L1 AHNAK2

3.14e-031511225PS50106
DomainCyt_P450_E_grp-I

CYP4A11 CYP4B1 CYP4A22

3.16e-03451223IPR002401
DomainPDZ

SHANK1 RHPN1 AHNAK SIPA1L1 AHNAK2

3.23e-031521225IPR001478
DomainSH3_domain

SHANK1 OBSCN RIMBP3 RIMBP3C RIMBP3B SNX9

3.25e-032201226IPR001452
DomainDynein_heavy_chain_D4_dom

DNAH3 DNAH6

3.66e-03141222IPR024317
DomainPP2C_SIG

PPM1E PPM1F

3.66e-03141222SM00331
DomainDynein_HC_stalk

DNAH3 DNAH6

3.66e-03141222IPR024743
DomainDynein_heavy_dom-2

DNAH3 DNAH6

3.66e-03141222IPR013602
DomainDHC_N2

DNAH3 DNAH6

3.66e-03141222PF08393
DomainMT

DNAH3 DNAH6

3.66e-03141222PF12777
DomainAAA_8

DNAH3 DNAH6

3.66e-03141222PF12780
DomainDHC_fam

DNAH3 DNAH6

4.20e-03151222IPR026983
DomainDynein_heavy

DNAH3 DNAH6

4.20e-03151222PF03028
DomainDynein_heavy_dom

DNAH3 DNAH6

4.20e-03151222IPR004273
DomainPPM_1

PPM1E PPM1F

4.20e-03151222PS01032
Domain-

SNX16 ZCCHC2 SNX9

4.51e-035112233.30.1520.10
DomainPhox

SNX16 ZCCHC2 SNX9

4.76e-03521223IPR001683
DomainPP2C

PPM1E PPM1F

5.40e-03171222IPR015655
PathwayREACTOME_EICOSANOIDS

CYP4A11 CYP4B1 CYP4A22

4.80e-0512873M27129
PathwayREACTOME_MISCELLANEOUS_SUBSTRATES

CYP4A11 CYP4B1 CYP4A22

4.80e-0512873M27128
PathwayREACTOME_EICOSANOIDS

CYP4A11 CYP4B1 CYP4A22

4.80e-0512873MM14845
PathwayREACTOME_FATTY_ACIDS

CYP4A11 CYP4B1 CYP4A22

9.79e-0515873M27126
PathwayREACTOME_MISCELLANEOUS_SUBSTRATES

CYP4A11 CYP4B1 CYP4A22

1.73e-0418873MM14843
PathwayREACTOME_FATTY_ACIDS

CYP4A11 CYP4B1 CYP4A22

1.73e-0418873MM14841
PathwayREACTOME_PROTEIN_PROTEIN_INTERACTIONS_AT_SYNAPSES

SHANK1 PTPRD SIPA1L1 SHARPIN SLITRK6

1.98e-0487875M27617
PathwayREACTOME_SYNTHESIS_OF_LEUKOTRIENES_LT_AND_EOXINS_EX

CYP4A11 CYP4B1 CYP4A22

2.79e-0421873M27137
PathwayREACTOME_BIOLOGICAL_OXIDATIONS

CYP26B1 CYP4A11 CYP4B1 PAPSS1 CYP4A22 GSTA1 GSTA2

4.05e-04219877MM14838
PathwayREACTOME_BIOLOGICAL_OXIDATIONS

CYP26B1 CYP4A11 CYP4B1 PAPSS1 CYP4A22 GSTA1 GSTA2

4.16e-04220877M10320
PathwayREACTOME_SYNTHESIS_OF_LEUKOTRIENES_LT_AND_EOXINS_EX

CYP4A11 CYP4B1 CYP4A22

4.73e-0425873MM14858
PathwayWP_OXIDATION_BY_CYTOCHROME_P450

CYP26B1 CYP4A11 CYP4B1 CYP4A22

5.75e-0462874M39653
PathwayREACTOME_RNA_POLYMERASE_III_TRANSCRIPTION_INITIATION_FROM_TYPE_1_PROMOTER

GTF3C4 GTF3C1 POLR3E

5.97e-0427873MM15457
PathwayREACTOME_CYTOCHROME_P450_ARRANGED_BY_SUBSTRATE_TYPE

CYP26B1 CYP4A11 CYP4B1 CYP4A22

6.48e-0464874M5650
PathwayREACTOME_RNA_POLYMERASE_III_TRANSCRIPTION_INITIATION_FROM_TYPE_1_PROMOTER

GTF3C4 GTF3C1 POLR3E

6.65e-0428873M27716
PathwayREACTOME_CYTOCHROME_P450_ARRANGED_BY_SUBSTRATE_TYPE

CYP26B1 CYP4A11 CYP4B1 CYP4A22

7.29e-0466874MM14839
PathwayWP_EICOSANOID_METABOLISM_VIA_LIPOOXYGENASES_LOX

TRPV1 CYP4A11 CYP4A22

7.39e-0429873M39858
PathwayBIOCARTA_RNAPOL3_PATHWAY

GTF3C4 GTF3C1

7.75e-047872M22046
PathwayWP_CONSTITUTIVE_ANDROSTANE_RECEPTOR_PATHWAY

NCOA6 CYP4A11 GSTA2

9.01e-0431873M39476
PathwayBIOCARTA_NUCLEARRS_PATHWAY

CYP4A11 CYP4B1 CYP4A22

1.08e-0333873MM1448
PathwayBIOCARTA_NUCLEARRS_PATHWAY

CYP4A11 CYP4B1 CYP4A22

1.18e-0334873M16393
PathwayREACTOME_RNA_POLYMERASE_III_TRANSCRIPTION

GTF3C4 GTF3C1 POLR3E

1.18e-0334873MM15435
PathwayWP_EICOSANOID_METABOLISM_VIA_CYTOCHROME_P450_MONOOXYGENASES_PATHWAY

CYP4A11 CYP4A22

1.32e-039872M39819
Pubmed

N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.

FAM193B ISYNA1 IRS4 AFTPH WASHC2C ICE1 RFC1 PRPF8 NSUN2 GTF3C4 GPALPP1 RBM12 AHNAK KIAA1217 PRDX1 CCT8 KMT2A SNX9 AHNAK2

1.45e-099341271933916271
Pubmed

Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.

IRS4 MYCBP2 MSANTD2 ICE1 RABGAP1 GTF3C4 GTF3C1 ZNF608 SLC16A1 PPM1F AHNAK CCT8 ZFHX3

5.00e-094181271334709266
Pubmed

Loss of ER retention motif of AGR2 can impact mTORC signaling and promote cancer metastasis.

IRS4 MYCBP2 EWSR1 PRPF8 NSUN2 GTF3C4 RYR1 MYOF GUF1 ARID1B MDN1 AHNAK PRDX1 CCT8 KMT2A ZFHX3 AHNAK2

6.85e-098071271730575818
Pubmed

Mapping genes encoding drug-metabolizing enzymes in recombinant inbred mice.

CYP4A11 CYP4A22 GSTA1 GSTA2

2.11e-08912741685137
Pubmed

PRISMA and BioID disclose a motifs-based interactome of the intrinsically disordered transcription factor C/EBPα.

NCOA6 ESS2 MYCBP2 MAML1 MSANTD2 EWSR1 RFC1 LCP1 NSUN2 GPALPP1 ARID1B RBM12 GTF3C1 PRDX1 CCT8 CPNE1 KMT2A SNX9 SNRPF

2.11e-0811031271934189442
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

FAM193B NCOA6 HIVEP2 MYCBP2 LAT2 OBSCN MAML1 TBC1D25 ICE1 TEP1 WASHC2A RYR1 RHPN1 MYOF SLC38A10 MDN1 RBM19 AHNAK AHNAK2

2.17e-0811051271935748872
Pubmed

A novel murine P-450 gene, Cyp4a14, is part of a cluster of Cyp4a and Cyp4b, but not of CYP4F, genes in mouse and humans.

CYP4A11 CYP4B1 CYP4A22

4.76e-08312739271096
Pubmed

MYC Protein Interactome Profiling Reveals Functionally Distinct Regions that Cooperate to Drive Tumorigenesis.

IRS4 ESS2 MAML1 PRPF8 NSUN2 GTF3C4 AAR2 BLM ARID1B GTF3C1 KMT2A

5.22e-083391271130415952
Pubmed

Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.

IRS4 MYCBP2 EWSR1 RFC1 LCP1 PRPF8 NSUN2 TASOR2 BLM MDN1 GTF3C1 AHNAK KMT2A SNX9

1.30e-076531271422586326
Pubmed

Targeting USP10 induces degradation of oncogenic ANLN in esophageal squamous cell carcinoma.

PKP4 EWSR1 RFC1 PRPF8 NSUN2 GTF3C4 TASOR2 AAR2 RALY MYOF GTF3C1 SLC16A1 RBM19 AHNAK KIAA1217 SIPA1L1 PRDX1 CCT8 SNRPF

1.62e-0712571271936526897
Pubmed

AHNAK, a novel component of the dysferlin protein complex, redistributes to the cytoplasm with dysferlin during skeletal muscle regeneration.

MYOF AHNAK AHNAK2

1.90e-074127317185750
Pubmed

RIM-BP3 is a manchette-associated protein essential for spermiogenesis.

RIMBP3 RIMBP3C RIMBP3B

1.90e-074127319091768
Pubmed

The Tumor Suppressor CIC Directly Regulates MAPK Pathway Genes via Histone Deacetylation.

IRS4 RFC1 PRPF8 GTF3C4 RALY GTF3C1 SLC16A1 POLR3E PRDX1 PNMA2 CCT8 ZFHX3 SNX9

2.41e-075831271329844126
Pubmed

Prohibitin 1 regulates tumor cell apoptosis via the interaction with X-linked inhibitor of apoptosis protein.

IRS4 EWSR1 PRPF8 NSUN2 GTF3C4 AAR2 MDN1 GTF3C1 SLC16A1 PPM1F PRDX1 CCT8 SNX9 SNRPF

4.58e-077251271427025967
Pubmed

Structure and evolution of RIM-BP genes: identification of a novel family member.

RIMBP3 RIMBP3C RIMBP3B

4.73e-075127317855024
Pubmed

Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.

MYCBP2 PKP4 RFC1 PRPF8 NSUN2 GTF3C4 AAR2 RALY BLM GUF1 MDN1 GTF3C1 SLC16A1 PPM1F RBM19 AHNAK PRDX1 CCT8 AHNAK2

4.94e-0713531271929467282
Pubmed

SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.

NCOA6 IRS4 MYCBP2 GTF3C4 ARID1B GTF3C1 SLC16A1 AHNAK PRDX1 CCT8 KMT2A SNX9

8.82e-075491271238280479
Pubmed

Synthetic Lethal and Resistance Interactions with BET Bromodomain Inhibitors in Triple-Negative Breast Cancer.

RABGAP1 RFC1 PRPF8 PAPSS1 NSUN2 GTF3C4 RALY BLM RBM12 MDN1 GTF3C1 AHNAK CCT8 CPNE1 KMT2A UBE2S

9.61e-0710141271632416067
Pubmed

Large-scale characterization of HeLa cell nuclear phosphoproteins.

NCOA6 AFTPH WASHC2C MYCBP2 RFC1 NSUN2 GTF3C4 BLM MYOF MDN1 GTF3C1 USP42 SIPA1L1 KMT2A

9.92e-077741271415302935
Pubmed

BAP1 regulation of the key adaptor protein NCoR1 is critical for γ-globin gene repression.

ESS2 EWSR1 RFC1 LCP1 PRPF8 NSUN2 RALY GPALPP1 GUF1 MDN1 USP42 SLC16A1 AHNAK PRDX1 CCT8 KMT2A UBE2S SNRPF

1.51e-0613181271830463901
Pubmed

Mapping the MOB proteins' proximity network reveals a unique interaction between human MOB3C and the RNase P complex.

NSUN2 GTF3C4 KIAA0753 MYOF MDN1 GTF3C1 AHNAK SIPA1L1 CCT8 FKBP8

2.24e-063991271037536630
Pubmed

E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.

DNAH3 CYP26B1 OBSCN ICE1 PRPF8 RYR1 SLC38A10 MDN1 GTF3C1 CEP95 AHNAK PRDX1 CCT8

3.20e-067361271329676528
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

NCOA6 IRS4 HIVEP2 AFTPH MYCBP2 KIAA0753 MDN1 SLC16A1 CEP95 AHNAK KIAA1217 SIPA1L1 KMT2A AHNAK2

3.42e-068611271436931259
Pubmed

MYC multimers shield stalled replication forks from RNA polymerase.

ESS2 EWSR1 RFC1 PRPF8 NSUN2 BLM MDN1 GTF3C1 USP42 SLC16A1 RBM19 AHNAK PRDX1 CCT8 SNRPF

3.48e-069891271536424410
Pubmed

Systematic analysis of human protein complexes identifies chromosome segregation proteins.

WASHC2C PRPF8 PAPSS1 WASHC2A NSUN2 GTF3C4 TASOR2 AAR2 RALY BLM ARID1B GTF3C1 PHF20L1 AHNAK BTG3 SNRPF

5.09e-0611551271620360068
Pubmed

Identification of proximal SUMO-dependent interactors using SUMO-ID.

ESS2 WASHC2C GTF3C4 BLM RBM12 ZNF608 AHNAK PRDX1 CCT8 AHNAK2

5.75e-064441271034795231
Pubmed

Wnt regulation: exploring Axin-Disheveled interactions and defining mechanisms by which the SCF E3 ubiquitin ligase is recruited to the destruction complex.

IRS4 MYCBP2 EWSR1 SNX16 RFC1 PRPF8 NSUN2 MDN1 SLC16A1 AHNAK PRDX1 CCT8 SNRPF

8.84e-068091271332129710
Pubmed

Mapping the Ku Interactome Using Proximity-Dependent Biotin Identification in Human Cells.

NCOA6 EWSR1 RFC1 GTF3C4 RALY BLM CCT8 ZFHX3

1.01e-05283127830585729
Pubmed

The Nse5/6-like SIMC1-SLF2 complex localizes SMC5/6 to viral replication centers.

NCOA6 IRS4 EWSR1 ICE1 RFC1 PRPF8 TASOR2 BLM ARID1B RBM19 AHNAK PRDX1 CCT8 KMT2A

1.09e-059541271436373674
Pubmed

Proteomic analysis of integrin-associated complexes identifies RCC2 as a dual regulator of Rac1 and Arf6.

EWSR1 LCP1 PRPF8 NSUN2 RALY RBM12 MDN1 AHNAK PRDX1 CCT8 CPNE1 SNRPF

1.16e-057071271219738201
Pubmed

Inhibition of calpain 1 restores plasma membrane stability to pharmacologically rescued Phe508del-CFTR variant.

KRT34 EWSR1 LCP1 NSUN2 RALY AHNAK PRDX1 CCT8 CPNE1 FKBP8

1.31e-054881271031324722
Pubmed

Fine mapping and candidate gene analysis of a dravet syndrome modifier locus on mouse chromosome 11.

TRPV1 SCN1A

1.32e-052127235606653
Pubmed

Functional variant of CYP4A11 20-hydroxyeicosatetraenoic acid synthase is associated with essential hypertension.

CYP4A11 CYP4A22

1.32e-052127215611369
Pubmed

Polymorphism of human Alpha class glutathione transferases.

GSTA1 GSTA2

1.32e-052127211668220
Pubmed

Human liver glutathione S-transferases: complete primary sequence of an Ha subunit cDNA.

GSTA1 GSTA2

1.32e-05212723800996
Pubmed

The eighth Cct gene, Cctq, encoding the theta subunit of the cytosolic chaperonin containing TCP-1.

TEP1 CCT8

1.32e-05212727890169
Pubmed

Nucleotide sequence of the human liver glutathione S-transferase subunit 1 cDNA.

GSTA1 GSTA2

1.32e-05212723678589
Pubmed

The basic glutathione S-transferases from human livers are products of separate genes.

GSTA1 GSTA2

1.32e-05212723036131
Pubmed

Androgen-sensitive hypertension associates with upregulated vascular CYP4A12-20-HETE synthase.

CYP4A11 CYP4A22

1.32e-052127223641057
Pubmed

The extended catalysis of glutathione transferase.

GSTA1 GSTA2

1.32e-052127221163259
Pubmed

Human glutathione S-transferase A2 polymorphisms: variant expression, distribution in prostate cancer cases/controls and a novel form.

GSTA1 GSTA2

1.32e-052127215128049
Pubmed

The Blood Pressure-Lowering Effect of 20-HETE Blockade in Cyp4a14(-/-) Mice Is Associated with Natriuresis.

CYP4A11 CYP4A22

1.32e-052127228912346
Pubmed

Altered inflammatory responses to Citrobacter rodentium infection, but not bacterial lipopolysaccharide, in mice lacking the Cyp4a10 or Cyp4a14 genes.

CYP4A11 CYP4A22

1.32e-052127224413902
Pubmed

Effect of polymorphism in the human glutathione S-transferase A1 promoter on hepatic GSTA1 and GSTA2 expression.

GSTA1 GSTA2

1.32e-052127211692074
Pubmed

Control of HIV replication in astrocytes by a family of highly conserved host proteins with a common Rev-interacting domain (Risp).

WASHC2C WASHC2A

1.32e-052127220827171
Pubmed

The AHNAKs are a class of giant propeller-like proteins that associate with calcium channel proteins of cardiomyocytes and other cells.

AHNAK AHNAK2

1.32e-052127215007166
Pubmed

Deduced amino acid sequence of a murine cytochrome P-450 Cyp4a protein: developmental and hormonal regulation in liver and kidney.

CYP4A11 CYP4A22

1.32e-05212728031839
Pubmed

FAM21 is critical for TLR2/CLEC4E-mediated dendritic cell function against Candida albicans.

WASHC2C WASHC2A

1.32e-052127236717248
Pubmed

Structural and functional investigation of the human snRNP assembly factor AAR2 in complex with the RNase H-like domain of PRPF8.

PRPF8 AAR2

1.32e-052127236322420
Pubmed

Human fatty acid omega-hydroxylase, CYP4A11: determination of complete genomic sequence and characterization of purified recombinant protein.

CYP4A11 CYP4A22

1.32e-052127210860550
Pubmed

Alterations in the regulation of androgen-sensitive Cyp 4a monooxygenases cause hypertension.

CYP4A11 CYP4A22

1.32e-052127211320253
Pubmed

Characterization of the CYP4A11 gene, a second CYP4A gene in humans.

CYP4A11 CYP4A22

1.32e-052127212464262
Pubmed

Evidence that glutathione S-transferases B1B1 and B2B2 are the products of separate genes and that their expression in human liver is subject to inter-individual variation. Molecular relationships between the B1 and B2 subunits and other Alpha class glutathione S-transferases.

GSTA1 GSTA2

1.32e-05212722604726
Pubmed

The Heat Sensing Trpv1 Receptor Is Not a Viable Anticonvulsant Drug Target in the Scn1a +/- Mouse Model of Dravet Syndrome.

TRPV1 SCN1A

1.32e-052127234079465
Pubmed

Expression of cytochrome P450 4A mRNA in mouse lung: effect of clofibrate and interleukin-1beta.

CYP4A11 CYP4A22

1.32e-052127215066132
Pubmed

Promoter-sharing by different genes in human genome--CPNE1 and RBM12 gene pair as an example.

RBM12 CPNE1

1.32e-052127218831769
Pubmed

Isolation of a cDNA clone and localization of human glutathione S-transferase 2 genes to chromosome band 6p12.

GSTA1 GSTA2

1.32e-05212723031680
Pubmed

20-HETE induces remodeling of renal resistance arteries independent of blood pressure elevation in hypertension.

CYP4A11 CYP4A22

1.32e-052127223825080
Pubmed

Salt-sensitive hypertension is associated with dysfunctional Cyp4a10 gene and kidney epithelial sodium channel.

CYP4A11 CYP4A22

1.32e-052127216691295
Pubmed

The P450 gene superfamily: recommended nomenclature.

CYP4A11 CYP4A22

1.32e-05212723829886
Pubmed

Sharpin, a novel postsynaptic density protein that directly interacts with the shank family of proteins.

SHANK1 SHARPIN

1.32e-052127211178875
Pubmed

Identification of a novel Rev-interacting cellular protein.

WASHC2C WASHC2A

1.32e-052127215847701
Pubmed

Induction of cytochrome P450 4A14 contributes to angiotensin II-induced renal fibrosis in mice.

CYP4A11 CYP4A22

1.32e-052127229277328
Pubmed

Genetic polymorphism of CYP4A11 and CYP4A22 genes and in silico insights from comparative 3D modelling in a French population.

CYP4A11 CYP4A22

1.32e-052127221820496
Pubmed

Genetic variation and haplotype structures of the glutathione S-transferase genes GSTA1 and GSTA2 in Japanese colorectal cancer patients.

GSTA1 GSTA2

1.32e-052127221844655
Pubmed

Renal function and vasomotor activity in mice lacking the Cyp4a14 gene.

CYP4A11 CYP4A22

1.32e-052127220943934
Pubmed

The rat clofibrate-inducible CYP4A subfamily. II. cDNA sequence of IVA3, mapping of the Cyp4a locus to mouse chromosome 4, and coordinate and tissue-specific regulation of the CYP4A genes.

CYP4A11 CYP4A22

1.32e-05212722766933
Pubmed

AHNAK1 and AHNAK2 are costameric proteins: AHNAK1 affects transverse skeletal muscle fiber stiffness.

AHNAK AHNAK2

1.32e-052127220833135
Pubmed

Human glutathione S-transferases. The Ha multigene family encodes products of different but overlapping substrate specificities.

GSTA1 GSTA2

1.32e-05212723138230
Pubmed

Heterologous expression of recombinant human glutathione transferase A1-1 from a hepatoma cell line.

GSTA1 GSTA2

1.32e-05212721330133
Pubmed

Mouse Cyp4a isoforms: enzymatic properties, gender- and strain-specific expression, and role in renal 20-hydroxyeicosatetraenoic acid formation.

CYP4A11 CYP4A22

1.32e-052127217112342
Pubmed

The role of GSTA2 polymorphisms and haplotypes in breast cancer susceptibility: a case-control study in the Portuguese population.

GSTA1 GSTA2

1.32e-052127219639209
Pubmed

Characterization of two novel subunits of the alpha-class glutathione S-transferases of human liver.

GSTA1 GSTA2

1.32e-05212728431482
Pubmed

High-fat diet-induced obesity and insulin resistance in CYP4a14-/- mice is mediated by 20-HETE.

CYP4A11 CYP4A22

1.32e-052127230088983
Pubmed

Mechanisms of podocyte injury in diabetes: role of cytochrome P450 and NADPH oxidases.

CYP4A11 CYP4A22

1.32e-052127219208908
Pubmed

C9orf72 protein quality control by UBR5-mediated heterotypic ubiquitin chains.

ISYNA1 IRS4 MYCBP2 EWSR1 RFC1 PRPF8 NSUN2 GTF3C4 AAR2 MDN1 GTF3C1 SLC16A1 PPM1F PRDX1 CCT8 FKBP8

1.46e-0512571271637317656
Pubmed

FBXO22 promotes leukemogenesis by targeting BACH1 in MLL-rearranged acute myeloid leukemia.

OBSCN LCP1 PRPF8 GTF3C4 MAP3K4 BLM MDN1 GTF3C1 KMT2A FKBP8

1.53e-054971271036774506
Pubmed

The human cytoplasmic dynein interactome reveals novel activators of motility.

AFTPH WASHC2C PKP4 MAML1 LCP1 WASHC2A RIMBP3 CEP95 PPM1F KIAA1217 SIPA1L1 CCT8 SNX9

1.54e-058531271328718761
Pubmed

Integrative characterization of germ cell-specific genes from mouse spermatocyte UniGene library.

RIMBP3 RIMBP3C RIMBP3B

1.68e-0514127317662146
Pubmed

Human transcription factor protein interaction networks.

NCOA6 IRS4 ESS2 MAML1 MSANTD2 EWSR1 RFC1 WASHC2A NSUN2 BLM ARID1B RBM12 GTF3C1 ZNF608 ZNF611 KMT2A ZFHX3

1.84e-0514291271735140242
Pubmed

ZMYM3 regulates BRCA1 localization at damaged chromatin to promote DNA repair.

GTF3C4 ARID1B MDN1 GTF3C1 PHF20L1 PRDX1

1.96e-05150127628242625
Pubmed

A protein-interaction network of interferon-stimulated genes extends the innate immune system landscape.

IRS4 RFC1 PRPF8 NSUN2 RALY MYOF MDN1 GTF3C1 AHNAK SIPA1L1 PRDX1 CCT8 KMT2A FKBP8 SNX9 SNRPF AHNAK2

2.02e-0514401271730833792
Pubmed

In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.

IRS4 KRT34 LCP1 PRPF8 TASOR2 AAR2 RALY GPALPP1 MDN1 GTF3C1 PHF20L1 ZNF608 AHNAK PRDX1 KMT2A SNX9 DNAH6

2.06e-0514421271735575683
Pubmed

The human immunodeficiency virus tat protein increases the transcription of human Alu repeated sequences by increasing the activity of the cellular transcription factor TFIIIC.

GTF3C4 GTF3C1 POLR3E

3.11e-051712731403646
Pubmed

Identification of SUMO Binding Proteins Enriched after Covalent Photo-Cross-Linking.

WASHC2C PRPF8 NSUN2 GTF3C4 MDN1 GTF3C1 AHNAK AHNAK2

3.17e-05332127832786267
Pubmed

Reciprocal interaction between SIRT6 and APC/C regulates genomic stability.

IRS4 MYCBP2 NSUN2 GTF3C4 MAP3K4 BLM ARID1B GTF3C1 SNX9

3.64e-05440127934244565
Pubmed

Genome-wide CRISPR-Cas9 Screen Identifies Leukemia-Specific Dependence on a Pre-mRNA Metabolic Pathway Regulated by DCPS.

LAT2 PRPF8 NSUN2 MDN1 RBM19 AHNAK PRDX1 SNRPF

3.76e-05340127829478914
Pubmed

PRP19 transforms into a sensor of RPA-ssDNA after DNA damage and drives ATR activation via a ubiquitin-mediated circuitry.

EWSR1 RFC1 PRPF8 RALY BLM MYOF AHNAK PRDX1

3.76e-05340127824332808
Pubmed

Genetic analysis of resistance to radiation lymphomagenesis with recombinant inbred strains of mice.

CYP4A11 CYP4A22

3.96e-05312722354437
Pubmed

Ablation of cytochrome P450 omega-hydroxylase 4A14 gene attenuates hepatic steatosis and fibrosis.

CYP4A11 CYP4A22

3.96e-053127228270609
Pubmed

The ubiquitin ligase MYCBP2 regulates transient receptor potential vanilloid receptor 1 (TRPV1) internalization through inhibition of p38 MAPK signaling.

TRPV1 MYCBP2

3.96e-053127221098484
Pubmed

Self-regulated alternative splicing at the AHNAK locus.

AHNAK AHNAK2

3.96e-053127221940993
Pubmed

H19/Mir-130b-3p/Cyp4a14 potentiate the effect of praziquantel on liver in the treatment of Schistosoma japonicum infection.

CYP4A11 CYP4A22

3.96e-053127237659685
Pubmed

Genetic variants and susceptibility to neurological complications following West Nile virus infection.

RFC1 SCN1A

3.96e-053127221881118
Pubmed

Novel human and mouse genes encoding a shank-interacting protein and its upregulation in gastric fundus of W/WV mouse.

SHANK1 SHARPIN

3.96e-053127212753155
Pubmed

Mouse cathepsin D gene: molecular organization, characterization of the promoter, and chromosomal localization.

CYP4A11 CYP4A22

3.96e-05312728011168
Pubmed

TLR3 deficiency impairs spinal cord synaptic transmission, central sensitization, and pruritus in mice.

TRPV1 TLR7

3.96e-053127222565312
Pubmed

Comparative expression of two alpha class glutathione S-transferases in human adult and prenatal liver tissues.

GSTA1 GSTA2

3.96e-053127212093480
Pubmed

The P450 superfamily: update on new sequences, gene mapping, and recommended nomenclature.

CYP4A11 CYP4A22

3.96e-05312721991046
Pubmed

Increased renal proximal convoluted tubule transport contributes to hypertension in Cyp4a14 knockout mice.

CYP4A11 CYP4A22

3.96e-053127219713718
InteractionSNRNP40 interactions

ESS2 EWSR1 RFC1 PRPF8 TASOR2 AAR2 RALY BLM GPALPP1 ARID1B PHF20L1 ZNF608 USP42 CCT8 KMT2A ZFHX3 SNRPF

3.78e-0763712417int:SNRNP40
InteractionNAA40 interactions

FAM193B ISYNA1 IRS4 AFTPH WASHC2C ICE1 RFC1 PRPF8 NSUN2 GTF3C4 GPALPP1 RBM12 AHNAK KIAA1217 PRDX1 CCT8 KMT2A SNX9 AHNAK2

8.30e-0697812419int:NAA40
Cytoband22q11.21

ESS2 RIMBP3 RIMBP3C RIMBP3B

2.66e-04111127422q11.21
CytobandEnsembl 112 genes in cytogenetic band chr20q11

NCOA6 AAR2 RALY RBM12 CPNE1

6.57e-042481275chr20q11
CytobandEnsembl 112 genes in cytogenetic band chr1p33

CYP4A11 CYP4B1 CYP4A22

6.62e-04611273chr1p33
GeneFamilyCytochrome P450 family 4

CYP4A11 CYP4B1 CYP4A22 CYP4F30P

2.17e-05368341003
GeneFamilyWASH complex

WASHC2C WASHC2A

3.09e-0468321331
GeneFamilyPDZ domain containing

SHANK1 RHPN1 AHNAK SIPA1L1 AHNAK2

6.74e-041528351220
GeneFamilyCopines

CPNE5 CPNE1

7.34e-049832829
GeneFamilyDyneins, axonemal

DNAH3 DNAH6

2.71e-0317832536
GeneFamilyProtein phosphatases, Mg2+/Mn2+ dependent

PPM1E PPM1F

2.71e-0317832701
GeneFamilyZinc fingers RANBP2-type |RNA binding motif containing

EWSR1 SHARPIN

4.13e-032183289
GeneFamilyGeneral transcription factors|Xeroderma pigmentosum complementation groups|DNA helicases|ERCC excision repair associated

GTF3C4 GTF3C1

5.83e-0325832565
GeneFamilyGlutathione S-transferases

GSTA1 GSTA2

5.83e-0325832567
GeneFamilySorting nexins|PX-BAR domain containing

SNX16 SNX9

7.80e-0329832754
ToppCellTracheal-NucSeq-Epithelial-Epi_airway_basal-Basal|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

ISYNA1 CYP4B1 OBSCN FSTL4 NCKAP5 MYOF SLITRK6 EPAS1

1.02e-07199126894a7867e800df352731796de8c24cba133c29622
ToppCellLPS_IL1RA-Endothelial-Endothelial-Gen_Cap|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

PKP4 VASH1 NCKAP5 NREP ZNF608 KIAA1217 KMT2A EPAS1

1.06e-072001268dccec522ab0d7fff62ad6273b02aa9022dbbb8eb
ToppCell10x5'v1-week_12-13-Hematopoietic-HSC/MPP_and_pro-ELP|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

ISYNA1 MYCBP2 LAT2 NREP RHPN1 PRDX1 CCT8

1.10e-0618812670a47de24812c619f6756c9351a413b109128d54f
ToppCellLPS-antiTNF-Endothelial-Endothelial-Gen_Cap|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PKP4 VASH1 NCKAP5 ZNF608 KIAA1217 SLC16A14 EPAS1

1.32e-0619312676e1982d089a9de628e6006d23ff78a223fbd9f47
ToppCellLPS_only-Endothelial-Endothelial-Gen_Cap|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PKP4 VASH1 NCKAP5 ZNF608 KIAA1217 SLC16A14 EPAS1

1.32e-061931267af5108260783e69a7d67896c5bf64f862525926d
ToppCellNS-critical-LOC-Epithelial-Ciliated|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

DNAH3 CYP4B1 EFHB GSTA1 GSTA2 OSCP1 DNAH6

1.41e-06195126734e37cff4849696ca4ba5dd8fd2cf98fed8bc912
ToppCellNS-critical-d_0-4-Epithelial-Ciliated-diff|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

DNAH3 CYP4B1 EFHB GSTA1 GSTA2 PRDX1 OSCP1

1.51e-06197126762e20ef825b92908d7732aa625dcff7b95ef6ca8
ToppCell5'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.2.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DNAH3 GSTA1 AHNAK KIAA1217 PRDX1 EPAS1 AHNAK2

1.51e-0619712675c4cee914baf7cb43e9cb99cc9e3ae823856dc15
ToppCellPBMC_fresh-frozen-Severe-critical_convalescent_d42-56-Myeloid-Dendritic-conventional_dendritic_cell-DC_c2-CD1C|Severe-critical_convalescent_d42-56 / Compartment, severity and other cell annotations on 10x 3' data (130k)

IL13RA1 NCKAP5 NREP RYR1 MYOF SERPINF2 UTF1

1.56e-061981267d0371e2ca9e25727b35985940f6228f9d8e49727
ToppCellPBMC_fresh-frozen-Severe-critical_convalescent_d42-56-Myeloid-Dendritic-conventional_dendritic_cell|Severe-critical_convalescent_d42-56 / Compartment, severity and other cell annotations on 10x 3' data (130k)

IL13RA1 NCKAP5 NREP RYR1 MYOF SERPINF2 UTF1

1.56e-06198126708ad0bece508bb4f9cc126d94839b5c89ce21ba8
ToppCellControl_saline|World / Treatment groups by lineage, cell group, cell type

CYP4B1 VASH1 NCKAP5 NREP AHNAK KIAA1217 EPAS1

1.61e-06199126711c9c1779caceb725ecccf3f23b7d4e6dbd1af64
ToppCellLPS_only-Endothelial-Endothelial-Gen_Cap|LPS_only / Treatment groups by lineage, cell group, cell type

PKP4 VASH1 NCKAP5 NREP ZNF608 KIAA1217 EPAS1

1.67e-062001267eb94a5111ef0e903ee5be9f7efe571b4e6d5fce1
ToppCellControl_saline-Endothelial-Endothelial-Gen_Cap|Control_saline / Treatment groups by lineage, cell group, cell type

PKP4 VASH1 NCKAP5 NREP ZNF608 KIAA1217 EPAS1

1.67e-0620012673b97920e1e6e2f09ddba2a861baa9c00c2970f4c
ToppCellLPS_anti-TNF-Endothelial-Endothelial-Activated_Gen_Cap|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

PKP4 VASH1 NCKAP5 NREP ZNF608 KIAA1217 EPAS1

1.67e-062001267f15fffefe372005c33e31845982e2d2714ac26af
ToppCellLPS_anti-TNF-Endothelial-Endothelial-Gen_Cap|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

PKP4 VASH1 NCKAP5 NREP ZNF608 KIAA1217 EPAS1

1.67e-062001267a2b9d1cd291d17abddc3ee2e242121412c864b8b
ToppCellLPS_IL1RA_TNF-Endothelial-Endothelial-Gen_Cap|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

PKP4 VASH1 NCKAP5 NREP ZNF608 KIAA1217 EPAS1

1.67e-062001267b2d4e6f3e8e4da62e6b02758ab2ed8f505269f9a
ToppCellPND28-Immune-Immune_Myeloid-DC|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

LAT2 LCP1 TEP1 RYR1 AHNAK UTF1

1.03e-051741266cfb4947caf7b1a856df246023fc6e5bfcc97ad36
ToppCellfacs-Thymus-Epithelium-3m-Myeloid-macrophage|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LAT2 PPM1E TLR7 RYR1 AHNAK SNX9

1.13e-051771266c2b8a3a149d70f77612759dea34df9e43953c566
ToppCellfacs-Thymus-Epithelium-3m-Myeloid-macrophage|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LAT2 PPM1E TLR7 RYR1 AHNAK SNX9

1.13e-051771266384f841aa7b2d05815af7885e481f5affc55d897
ToppCellfacs-Thymus-Epithelium-3m-Myeloid|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LAT2 PPM1E TLR7 RYR1 AHNAK SNX9

1.13e-0517712660e9e44119653abfd270e602e5e477a15e774638f
ToppCell368C-Myeloid-Dendritic-cDC_proliferating_1|Dendritic / Donor, Lineage, Cell class and subclass (all cells)

SMUG1 GTF3C4 EAF1 MDN1 MTX3 ZNF611

1.50e-0518612665cadab3271fce9ab6da3d7ba9827b8a221cac166
ToppCelldroplet-Tongue-nan-24m-Epithelial-suprabasal_differentiating|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IL13RA1 AGPAT3 GSTA1 GSTA2 MYOF PRDX1

1.60e-051881266b40146ed0af022422e6526116e5897c676ed9d71
ToppCell10x3'2.3-week_12-13-Hematopoietic-HSC/MPP_and_pro-ELP|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

ISYNA1 MYCBP2 LAT2 NREP RHPN1 PRDX1

1.65e-051891266af391c321753743709e2da01a5aa7782d8cc54e3
ToppCellhematopoetic_progenitors-CD34+_CLP|World / Lineage and Cell class

LAT2 NREP RHPN1 PTPRD PRDX1 CCT8

1.75e-05191126632f2537c97c9984629d61c6f34a337f555146ad4
ToppCell10x3'2.3-week_14-16-Hematopoietic-HSC/MPP_and_pro-ELP|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

MYCBP2 LAT2 NREP RHPN1 ZNF608 PRDX1

1.80e-05192126638ec82aa2ec4f2c0a843e83f7fe54f6b2483ca3d
ToppCellLPS-IL1RA+antiTNF-Endothelial-Endothelial-Gen_Cap|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PKP4 VASH1 NCKAP5 KIAA1217 SLC16A14 EPAS1

1.85e-051931266e09387af84d2a0a526e54d4793e6e06c6739db53
ToppCellNS-moderate-d_0-4|moderate / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

DNAH3 CYP4B1 EFHB ZNF608 DNAH6 AHNAK2

1.85e-051931266ea345d34440b25f65358a53dc72831998d1c3620
ToppCellLPS-IL1RA-Endothelial-Endothelial-Gen_Cap|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PKP4 NCKAP5 ZNF608 KIAA1217 SLC16A14 EPAS1

1.91e-0519412660b9cd96fa0b616da7cc90e92ff71157e9bba518f
ToppCellBAL-Severe-Myeloid-cDC-cDC-cDC_1|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

IL13RA1 LAT2 VASH1 TLR7 SERPINF2 UTF1

1.96e-0519512667bb3bdfb8caaae357b1f7841d8d00936c4373dfe
ToppCellPBMC_fresh-frozen-Severe-critical_convalescent_d42-56-Myeloid-Dendritic|Severe-critical_convalescent_d42-56 / Compartment, severity and other cell annotations on 10x 3' data (130k)

IL13RA1 NCKAP5 NREP RYR1 SERPINF2 UTF1

1.96e-0519512664cbc36fb3ef9aef61367d3b37070a9a85fae1418
ToppCellBAL-Severe-Myeloid-cDC-cDC-cDC_1|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

IL13RA1 LAT2 VASH1 TLR7 SERPINF2 UTF1

1.96e-051951266d579150d176e6bd81004b5146de4901ca13a3c3e
ToppCellsevere-Myeloid-CD16_Monocytes|Myeloid / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

AGPAT3 VASH1 MYOF AHNAK PRDX1 SNX9

1.96e-0519512665badcfdeed2fb7453a9c144506ca91c5475cd35f
ToppCellBL-critical-LOC-Epithelial-Ciliated|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

DNAH3 EFHB GSTA1 GSTA2 OSCP1 DNAH6

1.96e-05195126607a6bcef6af93ed87df455dee624037cb75e011a
ToppCellNS-moderate-d_07-13-Epithelial-Ciliated-diff|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

CYP4B1 EFHB GSTA1 GSTA2 OSCP1 DNAH6

2.02e-0519612669a91a6e5f93ce3bb5a0fc63677553f4c2df95c43
ToppCellNS-critical-d_07-13-Epithelial-Ciliated-diff|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

CYP4B1 GSTA1 GSTA2 PRDX1 OSCP1 DNAH6

2.08e-05197126632484fb5dde0a4525dd8028dde01ca5a4e51e4b6
ToppCellCOPD-Endothelial-VE_Capillary_B|Endothelial / Disease state, Lineage and Cell class

WASHC2C NCKAP5 WASHC2A OPHN1 KIAA1217 EPAS1

2.08e-05197126630dbc05ea66892d2e18ff375ffa86d1db7bc4083
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.4|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DNAH3 CYP4B1 EFHB GSTA1 OSCP1 DNAH6

2.08e-051971266d83c61d2b5742e463122e1a98c7197a5b5b3d41b
ToppCell3'-Broncho-tracheal-Epithelial-Airway_epithelium-respiratory_basal_cell-Suprabasal-Suprabasal_L.0.0.1.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CYP4B1 GSTA1 MYOF PRDX1 EPAS1 AHNAK2

2.14e-0519812669718f4c013c347f1b3c785ae232dd2fb6c1fe298
ToppCellHealthy-cDC|World / disease group, cell group and cell class

IL13RA1 LAT2 NCKAP5 NREP RYR1 UTF1

2.14e-0519812668976f8d26cb7ff79f74def138c4bbbb0bc2eaf00
ToppCellCOVID-19_Mild|World / Disease condition and Cell class

EWSR1 ZCCHC2 LCP1 EAF1 AHNAK MTCH1

2.14e-05198126661ceb2245b6cb58e308b999a61d218c89dbc615e
ToppCellBronchial_Biopsy|World / Tissue, Lineage and Cell class of Lung Cells from 10X

ISYNA1 ZNF608 KIAA1217 SLITRK6 EPAS1 AHNAK2

2.14e-051981266f5b7013045b61fc56894f80092f799770dde1c8f
ToppCellNS-control-d_0-4-Epithelial-Secretory|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

MYCBP2 MYOF PHF20L1 KIAA1217 SLITRK6 EPAS1

2.20e-05199126632bdfff40fd442b88489c8b0f79af3927a51a03c
ToppCell5'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-club_cell-Club_(nasal)-Club_(nasal)_L.0.2.1.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

RYR1 MYOF AHNAK PRDX1 EPAS1 AHNAK2

2.20e-051991266ba284f984909504221900bca5ea12ada5b2ffd9f
ToppCellcontrol-Epithelial-Secretory|control / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

MYCBP2 MYOF PHF20L1 KIAA1217 SLITRK6 EPAS1

2.20e-051991266262e5b8a52c8ddb0b47048c786e8bdb7158e1b9a
ToppCellcontrol|World / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

CYP4B1 MYOF AHNAK KIAA1217 EPAS1 AHNAK2

2.26e-05200126697f36d2c197e03d93a1fc59949d77ae90f6e6a9a
ToppCellLPS_IL1RA-Endothelial-Endothelial-Activated_Gen_Cap|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

HIVEP2 PKP4 VASH1 ZNF608 KMT2A EPAS1

2.26e-0520012662d07237022b409c4fac6fcf99b68c8affb3007cd
ToppCellLPS_only-Endothelial|LPS_only / Treatment groups by lineage, cell group, cell type

PKP4 VASH1 NREP ZNF608 KIAA1217 EPAS1

2.26e-05200126681e76508c9050d533853d5fd2f3097b27613d836
ToppCellcontrol-cDC|control / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

IL13RA1 NCKAP5 NREP RYR1 ZFHX3 SERPINF2

2.26e-0520012664a6d17a4225be38537d3dd8a39512051f597f4e0
ToppCellCOVID-19|World / Disease, condition lineage and cell class

MYCBP2 ZCCHC2 LCP1 ARID1B AHNAK KMT2A

2.26e-0520012667dec470c379cd89f05a0f37c8628b21f136e52f0
ToppCellLPS_IL1RA_TNF-Endothelial-Endothelial-Activated_Gen_Cap|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

PKP4 VASH1 NREP ZNF608 KIAA1217 EPAS1

2.26e-0520012663585484c7e24e941708bee471ca607d8ccee74e6
ToppCellNS-control|NS / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

CYP4B1 MYOF AHNAK KIAA1217 EPAS1 AHNAK2

2.26e-052001266ecbe89ff95d046155b984c8c150e0b9e7278f839
ToppCellsevere-cDC|severe / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

IL13RA1 NREP MYOF ZFHX3 SERPINF2 UTF1

2.26e-05200126626e04ea276dbca5cde48335c401269c7123b54d2
ToppCellLPS_only-Endothelial-Endothelial|LPS_only / Treatment groups by lineage, cell group, cell type

PKP4 VASH1 NREP ZNF608 KIAA1217 EPAS1

2.26e-0520012664bb609a284d4e6066f17470a1736076aa4a1f84c
ToppCellkidney_cells-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_1_/_Segment_2|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

SLC38A10 GTF3C1 MTX3 SERPINF2 SNX9

5.79e-05145126547a3bb973a508d3097213a2d86ad1ce697af9bae
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d03-09-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c08-GZMK-FOS_h|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)

TRPV1 TEP1 RHPN1 BTG3 CPNE1

5.98e-051461265deeb2c90a478deac7805e1f0d1466bf5bc42f746
ToppCellPND14-Immune-Immune_Myeloid-DC-cDC2-cDC2_mature|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

LAT2 LCP1 TEP1 RYR1 AHNAK

7.24e-051521265b2e29fbda6b5f2d87cfc05423caf9cbf3b04ac65
ToppCellLPS_only-Epithelial_airway-Ciliated_cells-Ciliated|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DNAH3 GSTA2 RHPN1 OSCP1 DNAH6

7.70e-0515412659ca71d440c4f87781e6525b8141e7d8d470b6a8e
ToppCellLPS_only-Epithelial_airway-Ciliated_cells|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DNAH3 GSTA2 RHPN1 OSCP1 DNAH6

7.70e-05154126558072ce422d09f2de602580325eaac6c4ec6c136
ToppCellPBMC-Mild-Myeloid-cDC-cDC-cDC_6|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

IL13RA1 NREP RYR1 OSCP1 UTF1

8.96e-0515912656115cb03c2ad08e4c1b65893d522f685ff0bc692
ToppCellPBMC-Mild-Myeloid-cDC-cDC-cDC_6|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

IL13RA1 NREP RYR1 OSCP1 UTF1

9.22e-051601265a90eb621481fd07a821495db07d1032e109fd386
ToppCellTCGA-Brain-Primary_Tumor-Low_Grade_Glioma-Oligoastrocytoma|TCGA-Brain / Sample_Type by Project: Shred V9

RABGAP1 RYR1 OPHN1 MDN1 PTPRD

9.50e-051611265347edb0de10850b7d16c40945751033289289c9b
ToppCellE16.5-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Deuterosomal-Deuterosomal_G2M|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

KRT34 CPNE5 SPATS1 SNX9 DNAH6

1.04e-041641265d9531848105d606adedde65426177cf851140e31
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT2_L6_FEZF2|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

GSTA1 MYOF KIAA1217 ZFHX3 SLITRK6

1.13e-041671265a6ff7a3d9b80839c0efa91658836812e868561fa
ToppCellControl-B_intermediate-1|Control / disease group and sub_cluster of B and Plasma cells(res = 0.5)

WASHC2C ICE1 WASHC2A MDN1 AHNAK

1.13e-041671265948504367ecf58144d9dd74d2ec531358fc4b309
ToppCellPND03-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP2-CAP2_prolif|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CYP4B1 AGPAT3 VASH1 BLM EPAS1

1.16e-041681265c7021748003e5949f7caf7b3291c5bad294948c1
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT2_L6_FEZF2-Exc_L6_FEZF2_TBC1D26|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

NREP MYOF KIAA1217 ZFHX3 SLITRK6

1.19e-0416912652abdd8ae9a5d88aac30992142d1b502c959bc015
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT2_L6_FEZF2|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

GSTA1 MYOF KIAA1217 ZFHX3 SLITRK6

1.19e-0416912650c341f91dc21aaf92bead18d59684d11510502ce
ToppCelldroplet-Limb_Muscle-MUSCLE-1m-Myeloid-unknown|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LAT2 PPM1E TLR7 LCP1 BLM

1.19e-041691265bca5322880c09b78ef10d9dda6420a80c1ba7e62
ToppCellPND28-Immune-Immune_Myeloid-DC-cDC2|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

LAT2 LCP1 TEP1 MYOF AHNAK

1.26e-041711265e01bef6d814c0b7bd015c71e20a194e2dec68377
ToppCellCOVID_vent-Lymphocytic-Dendritic-pDC|COVID_vent / Disease condition, Lineage, Cell class and subclass

TLR7 NREP SERPINF2 SNX9 AHNAK2

1.26e-041711265779c951d274ecbd1d546ac425d6c8e718623be5a
ToppCellCOVID_vent-Lymphocytic-Dendritic|COVID_vent / Disease condition, Lineage, Cell class and subclass

TLR7 NREP SERPINF2 SNX9 AHNAK2

1.26e-041711265debbb071d260639b16269c94d172766908325c58
ToppCellPND28-Immune-Immune_Myeloid-DC-cDC2-cDC2_mature|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

LAT2 LCP1 TEP1 MYOF AHNAK

1.26e-04171126541f858831a2919a2cacea62f51c2b723eb87b9c4
ToppCelldroplet-Lung-1m-Hematologic-myeloid-myeloid_dendritic_cell-myeloid_dendritic_type_1|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ISYNA1 HIVEP2 LAT2 TEP1 RYR1

1.26e-04171126538a05b5ec8ef8f09a2399994c6b4b9a707918ec1
ToppCelldroplet-Lung-3m-Hematologic-myeloid-myeloid_dendritic_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ISYNA1 LAT2 TEP1 RYR1 UTF1

1.33e-041731265f66aebceb3eb389bc5ff6c0b398d6f4e9959a14f
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT2_L6_FEZF2-Exc_L6_FEZF2_TBCC|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

IRS4 MYOF RIMBP3C ZFHX3 SLITRK6

1.33e-041731265d8b5e2c31fcc38998b7f8f5e9babb6fb5c0962da
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT2_L6_FEZF2-Exc_L6_FEZF2_TBCC|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

GSTA1 MYOF KIAA1217 ZFHX3 SLITRK6

1.37e-041741265912a9e892b29d945666fc37c986009c97c668ac8
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT2_L6_FEZF2-Exc_L6_FEZF2_TBCC|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

IRS4 GSTA1 MYOF ZFHX3 SLITRK6

1.37e-041741265e0de0a14319be1a115e5be05d6f9b562e7b32c4a
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT2_L6_FEZF2|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

GSTA1 MYOF KIAA1217 ZFHX3 SLITRK6

1.37e-0417412657d4b860e05b5931f6f9d757a68f75ff35597a47a
ToppCelldroplet-Marrow-nan-24m-Myeloid-monocyte|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IL13RA1 LAT2 TEP1 AHNAK PRDX1

1.44e-041761265eddac2ba68d234e3f56f4ca0e11c19bc0e95b6e1
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT2_L6_FEZF2|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

GSTA1 MYOF KIAA1217 ZFHX3 SLITRK6

1.44e-041761265ed421d8525108d2f585265d2cf777f07b29f44f0
ToppCellControl|World / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CYP4B1 NCKAP5 GSTA2 AHNAK KIAA1217

1.48e-041771265b8ff6940e31b749776e81ae4f5bbd577dba9749c
ToppCell3'-Airway_Nasal-Epithelial-Airway_epithelium-respiratory_basal_cell-Suprabasal-Suprabasal_L.0.0.3.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ISYNA1 CYP4B1 KRT34 PRDX1 EPAS1

1.48e-041771265aadf1d10eccfb014cf3d621b1f01dd6d76df63ac
ToppCellTCGA-Colorectal-Primary_Tumor-Colorectal_Adenocarcinoma-Rectal_Adenocarcinoma|TCGA-Colorectal / Sample_Type by Project: Shred V9

NCOA6 AAR2 RALY CPNE1 SPATA25

1.60e-041801265c3d1521ac90f2e3fc31158e6e61907e05c37af39
ToppCellE16.5-samps-Endothelial-Immature_fetal_endothelial-Intermediate_Endothelial|E16.5-samps / Age Group, Lineage, Cell class and subclass

CYP26B1 CYP4B1 ZNF608 PPM1F EPAS1

1.69e-041821265fec1caf867b1dc87b24504d895ee1a27df78062e
ToppCellCOVID-19_Mild-NK_activated|COVID-19_Mild / Disease condition and Cell class

WASHC2C ICE1 LCP1 WASHC2A AHNAK

1.73e-04183126522bd05135906d0ecc4ba8c2e0a666093d1bf3b8f
ToppCell5'-GW_trimst-2-LymphNode-Endothelial|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

OR10H5 PKP4 VASH1 CPNE5 EPAS1

1.77e-041841265df2d42e1eae29fa0a1ed9e389c95b38952b46892
ToppCell5'-GW_trimst-2-LymphNode-Endothelial-blood_vessel_EC|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

OR10H5 PKP4 VASH1 CPNE5 EPAS1

1.77e-0418412651ace70f12b417185bdd46042833f72b3b6815966
ToppCelldroplet-Marrow-nan-3m|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYCBP2 ZNF608 AHNAK KMT2A SNX9

1.77e-0418412651154a5ad7b8512272b7476f949ddac350910bfb7
ToppCell3'_v3-lymph-node_spleen-Lymphocytic_Invariant-Inducer-like-ILC3|lymph-node_spleen / Manually curated celltypes from each tissue

SHANK1 NREP PTPRD KIAA1217 EPAS1

1.77e-041841265479e60f76c191253e23699c9dd7ef7efc08c59ad
ToppCelldroplet-Fat-Mat-18m-Endothelial-nan|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CYP26B1 CYP4B1 PKP4 PPM1E EPAS1

1.82e-041851265d9be5853acdda7b1ac819cf50c7940d1d2362d15
ToppCellproximal-3-Hematologic-Myeloid_Dendritic_Type_1|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

VASH1 ZCCHC2 RBM12 ZNF578 SERPINF2

1.86e-041861265c920dffd24f051b54d8b48f801fffc928d99e135
ToppCellproximal-Hematologic-Myeloid_Dendritic_Type_1-3|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

VASH1 ZCCHC2 RBM12 ZNF578 SERPINF2

1.86e-041861265d740aca5dc4240851ba7bc5988c0970d785ad0c2
ToppCellThalamus-Endothelial|Thalamus / BrainAtlas - Mouse McCarroll V32

IL13RA1 ISYNA1 MYOF AHNAK EPAS1

1.86e-041861265dcc6e4417c4123d5ca6b96fa8ca4874626aaebdb
ToppCellproximal-Hematologic-Myeloid_Dendritic_Type_1|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

VASH1 ZCCHC2 RBM12 ZNF578 SERPINF2

1.86e-0418612654ca7f6c043874a0c536f75af5ca24c7c66725e54
ToppCell3'-GW_trimst-2-LargeIntestine-Endothelial-blood_vessel_EC-Fetal_arterial_EC|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

VASH1 RHPN1 PPM1F SLC16A14 EPAS1

1.91e-04187126525efb82afe863a853ecdd781ad89026c993aaa67
ToppCellCOPD-Endothelial-VE_Capillary_A|Endothelial / Disease state, Lineage and Cell class

FSTL4 OPHN1 KIAA1217 ZFHX3 EPAS1

1.96e-0418812651aa0e35b1c28ac847886fece16c3ef7fc6fcdd51
ToppCellTransplant_Alveoli_and_parenchyma-Epithelial-Ciliated_1|Transplant_Alveoli_and_parenchyma / Tissue, Lineage and Cell class of Lung Cells from 10X

DNAH3 EFHB GSTA1 SLITRK6 DNAH6

2.01e-041891265dc440015949a768188c67661b6be63b1ead1a0f0
ToppCellcellseq2-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

DNAH3 EFHB GSTA2 SPATS1 DNAH6

2.01e-041891265a3cd4c2da4feb9bdcd8957f3e344d095da1367b8
ToppCell3'-GW_trimst-1-SmallIntestine-Endothelial-blood_vessel_EC-Mature_arterial_EC|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CYP26B1 VASH1 CPNE5 PPM1F EPAS1

2.01e-0418912651d660bceee449aebf12fc9af4c74af246837b27a
ToppCellcellseq2-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

DNAH3 EFHB GSTA2 SPATS1 DNAH6

2.01e-04189126593b1026bb1ba759e5704561c9a5de14a30c08894
Diseasesuntan

NCOA6 AAR2 RALY KIAA1217 CPNE1

4.89e-051031135EFO_0004279
Diseaseurate measurement, spine bone mineral density

FAM193B LCP1 PTPRD SNX9

7.38e-05581134EFO_0004531, EFO_0007701
DiseaseCoughing

TRPV1 KNG1

8.68e-0541132C0010200
DiseaseSarcomatoid Renal Cell Carcinoma

SHANK1 RYR1 AHNAK BTG3 EPAS1

1.37e-041281135C1266043
DiseaseChromophobe Renal Cell Carcinoma

SHANK1 RYR1 AHNAK BTG3 EPAS1

1.37e-041281135C1266042
DiseaseCollecting Duct Carcinoma of the Kidney

SHANK1 RYR1 AHNAK BTG3 EPAS1

1.37e-041281135C1266044
DiseasePapillary Renal Cell Carcinoma

SHANK1 RYR1 AHNAK BTG3 EPAS1

1.37e-041281135C1306837
DiseaseRenal Cell Carcinoma

SHANK1 RYR1 AHNAK BTG3 EPAS1

1.37e-041281135C0007134
DiseaseX-14939 measurement

CYP4A11 CYP4A22

2.16e-0461132EFO_0800747
DiseaseConventional (Clear Cell) Renal Cell Carcinoma

SHANK1 RYR1 AHNAK BTG3 EPAS1

2.69e-041481135C0279702
Diseasehereditary angioedema (is_implicated_in)

MYOF KNG1

3.01e-0471132DOID:14735 (is_implicated_in)
Disease10-undecenoate 11:1n1 measurement

CYP4A11 CYP4B1

3.01e-0471132EFO_0021099
DiseaseX-18899 measurement

CYP4A11 CYP4B1

3.01e-0471132EFO_0800793
DiseaseX-24748 measurement

CYP4A11 CYP4B1

4.01e-0481132EFO_0022136
Diseasepimeloylcarnitine/3-methyladipoylcarnitine (C7-DC) measurement

CYP4A11 CYP4B1

4.01e-0481132EFO_0800494
DiseaseAttached earlobe

HIVEP2 KIAA1217

4.01e-0481132HP_0009907
Diseaseattention deficit hyperactivity disorder, conduct disorder

FSTL4 PKD1L3 PTPRD

4.87e-04401133EFO_0003888, EFO_0004216
Diseaseautosomal recessive polycystic kidney disease (biomarker_via_orthology)

CYP4A11 CYP4A22

7.82e-04111132DOID:0110861 (biomarker_via_orthology)
Diseaselipoprotein A measurement

LCP1 MAP3K4 ARID1B SNX9

9.21e-041121134EFO_0006925
Diseaseundecenoylcarnitine (C11:1) measurement

CYP4A11 CYP4B1

1.10e-03131132EFO_0800588
Diseasetriacylglycerol 52:2 measurement

AGPAT3 NCKAP5 LCP1

1.24e-03551133EFO_0010414
Diseasecerebellum cortex volume change measurement

PTPRD EPAS1

1.28e-03141132EFO_0021497
Disease1,3,7-trimethylurate measurement

GSTA1 GSTA2

1.48e-03151132EFO_0021172
Diseaseneuroticism measurement, cognitive function measurement

PKD1L3 NREP GTF3C1 PHF20L1 KIAA1217 SIPA1L1 CPNE1 ZFHX3

1.53e-035661138EFO_0007660, EFO_0008354
DiseaseChromosome Aberrations

KMT2A EPAS1

1.68e-03161132C0008625
DiseaseAutosome Abnormalities

KMT2A EPAS1

1.68e-03161132C0004403
Diseasepartial epilepsy

PTPRD SCN1A

1.90e-03171132EFO_0004263
Diseasecopine-1 measurement

AAR2 CPNE1

1.90e-03171132EFO_0008102
Diseasecognitive function measurement, self reported educational attainment

MYCBP2 PPM1E POU3F2 PKD1L3 NREP ARID1B

2.50e-033551136EFO_0004784, EFO_0008354
Diseasesarcopenia

ZCCHC2 PTPRD

2.64e-03201132EFO_1000653
Diseaseautism spectrum disorder (implicated_via_orthology)

SHANK1 PKP4 ARID1B SCN1A

2.82e-031521134DOID:0060041 (implicated_via_orthology)
DiseaseCOVID-19 (is_implicated_in)

TLR7 SERPINF2

2.91e-03211132DOID:0080600 (is_implicated_in)
Diseasehaptoglobin measurement

PKD1L3 ZFHX3

2.91e-03211132EFO_0004640
DiseasePR interval

MYCBP2 OBSCN NCKAP5 NREP CEP95 SIPA1L1 EPAS1

3.01e-034951137EFO_0004462
Diseaseintellectual disability (implicated_via_orthology)

IRS4 HIVEP2 NSUN2

3.02e-03751133DOID:1059 (implicated_via_orthology)

Protein segments in the cluster

PeptideGeneStartEntry
GPIPGLSKSPKGVEM

PKP4

806

Q99569
RKKPPMNSMRGGLPP

EWSR1

446

Q01844
KNLRGGSCPLMPDKP

EPAS1

741

Q99814
PFSGVRPQGMSKKPQ

CXorf49;

356

A8MYA2
GDKLFGPDLKLVPPM

SERPINF2

466

P08697
IPGLPRSPSGKMKGL

AMBN

361

Q9NP70
GLGMLEPTKEPLKPL

AFTPH

756

Q6ULP2
VGPKFRGVKMIPPGI

AAR2

41

Q9Y312
KLREFVQMKLPPGFP

ANKRD13C

481

Q8N6S4
PVTFPDGRSLPKGIM

CYP4A11

396

Q02928
IKFPKFSMPKIGIPG

AHNAK

5231

Q09666
EPNKDPFGGMRKVPG

ARID1B

1346

Q8NFD5
PGSTPPMTVFKGNKR

EAF1

66

Q96JC9
TDGPGRNILKFKPPM

PHYKPL

401

Q8IUZ5
KIPKMEVLSPASPGG

MSANTD2

16

Q6P1R3
GKPGPTVIKVQNMPF

RBM12

851

Q9NTZ6
DINMAGEPKPDRPKG

RALY

86

Q9UKM9
AGQEQGMPAGKKRPP

RBM19

261

Q9Y4C8
LASKPPGPKGFSRMD

PGBD4

131

Q96DM1
PSAKVIKMPRGGPQQ

RIMBP3B

1431

A6NNM3
PSAKVIKMPRGGPQQ

RIMBP3C

1431

A6NJZ7
KFLQPGSPRKPPMDE

GSTA1

196

P08263
TPMEQKPGAKQGPLD

OPHN1

301

O60890
PMLNKKGPVPAATNG

ISYNA1

526

Q9NPH2
PLPGFKSAKPMVFAG

GUF1

346

Q8N442
PLMGGQDKPFLSARP

KIR3DL2

21

P43630
VCGPPPSKKMKLFGF

NSUN2

501

Q08J23
KPEMSLPVKPGQGDS

RABGAP1

116

Q9Y3P9
SLFLMKPKPGNMPFR

MAML1

556

Q92585
AGALMRPIGPKPTKA

SLC16A1

191

P53985
PFPLSLILPGRMSKG

MTX3

131

Q5HYI7
MEGRLPKGRLPVPKE

NREP

21

Q16612
LKPKGPQSPEGDTLM

OR10H5

261

Q8NGA6
DPKLEKPGTFLSPMG

KLHL33

391

A6NCF5
KVPIFKGPGEMPEIR

MDN1

5541

Q9NU22
KLPIPKGSMGFPLIG

CYP26B1

46

Q9NR63
KFLQPGSPRKPPMDE

GSTA2

196

P09210
RVNKPPYPKLGGNMK

LCP1

441

P13796
PKRMRGPAQAKLLPG

KCT2

6

Q8NC54
KDQGPPPSFLELMKV

PNMA2

316

Q9UL42
FLNMPGDAPIAPVKG

MFSD11

326

O43934
PPIPDPGKIFKEMFG

IL13RA1

376

P78552
GLGPMNIPLVSDPKR

PRDX1

96

Q06830
LLPVEMFGPGAPKKA

PPM1E

586

Q8WY54
SKMGPGDISLPGRPK

OBSCN

7096

Q5VST9
MPKRLPPGFSAGQAN

NCOA6

511

Q14686
REGQKPPEGFMAPKA

PAPSS1

596

O43252
KGPELMGPSESKPRG

ERVK-10

166

P87889
KGPELMGPSESKPRG

HERVK_113

166

P62684
KFGSALGKMSREPPP

ESS2

86

Q96DF8
KLEFALMPPAEGKIP

DNAH6

1226

Q9C0G6
KMLGNPSRLPAKCPG

FKBP8

366

Q14318
KAMPFLQNRGPTPKP

ICE1

821

Q9Y2F5
GANSKLGIMAPPKPI

BLM

1391

P54132
KGMKPERKPDPSGSG

DNAH3

2806

Q8TD57
GLVLQGEKLPPDFMP

FAM193B

101

Q96PV7
PVTFPDGRSLPKGIM

CYP4A22

396

Q5TCH4
VGMLKNLKEPPAGPA

FSTL4

771

Q6MZW2
MARDLIGPALPPGFK

GPALPP1

1

Q8IXQ4
PPEMKDFGLGPRTFK

GPALPP1

196

Q8IXQ4
KGRVMPVLKSPTIPF

CSN2

111

P05814
KQGALCGMKPPFLPE

CYP4F30P

86

Q9H0H9
RGGLPKPNKAVPMKV

CEP95

546

Q96GE4
RMAPPETKFPLSKGL

EFHB

56

Q8N7U6
GVPKAPPMQVEGSAK

KMT2A

2496

Q03164
QPLGMISLMKRPPGF

KNG1

371

P01042
RQTLAKAMDKFPGPP

CYP4B1

36

P13584
GPGAETGDPRMKPKQ

SLC38A10

916

Q9HBR0
PKRDVEGMGPPEIKY

RYR1

326

P21817
MPKKPDAQSGPAGLV

POLR3E

441

Q9NVU0
DKMFPALGFGAKLPP

CPNE5

376

Q9HCH3
TLPLMLKPGKPAGRG

CPNE1

111

Q99829
KMPTGPPEDRLSLKF

DRICH1

66

Q6PGQ1
LAMGFLGSRKAPPPL

PPM1F

61

P49593
IPRGFPTIDMGPQLK

PTPRD

121

P23468
MSKKPPNRPGITFEI

PHF20L1

1

A8MW92
FMAPGAGAIPKNPRN

IRS4

781

O14654
YKVGMGHKPPIPERL

MAP3K4

1556

Q9Y6R4
PGPLADMAPTRKDKL

LAT2

66

Q9GZY6
EPMPPTLGTNVLGRK

MTCH1

111

Q9NZJ7
MKIPLNKFPGFAKPG

SNX9

201

Q9Y5X1
AIKEILPGTFNPMPK

SLITRK6

446

Q9H5Y7
SPLMQEVGSPKDPGK

TBC1D25

581

Q3MII6
MLYAKPPPTINGIKG

KRT34

1

O76011
LKELSPGIFGPMPNL

LRRC15

281

Q8TF66
VMALGPPKVSPKRGV

NCKAP5

1031

O14513
GALMRPLSPGKNPND

SLC16A14

206

Q7RTX9
SIAFKEGLKIPPPAM

RFC1

786

P35251
PSAKVIKMPRGGPQQ

RIMBP3

1431

Q9UFD9
PMGLPRPIRLNKKEF

PRR14

461

Q9BWN1
KRGVAIARDKMPPGP

PKD1L3

166

Q7Z443
SRLNAGKGDGKMPPP

SIPA1L1

1091

O43166
GKGDGKMPPPERAAN

SIPA1L1

1096

O43166
PMSAKNRPGTLDKPG

KIAA1217

1751

Q5T5P2
PQKMDGELGRLFPPS

SHARPIN

316

Q9H0F6
KPAPMPNIGSKYGRK

MYCBP2

1036

O75592
QQKEGRAPLFVPPGM

KIAA0753

881

Q2KHM9
MEIKKPSGPEPGFRL

OSCP1

306

Q8WVF1
RQKEKRMTPPGGTLP

POU3F2

406

P20265
KPEARMPRLSQGKGP

RHPN1

476

Q8TCX5
KMPLVRSKRGQPPGS

SPATA25

211

Q9BR10
KPIPRPGNKFQGMVF

SCN1A

1521

P35498
SFLPPGPGLMLRQKS

SHANK1

876

Q9Y566
HPLPRKKPGMYRGNG

BTG3

186

Q14201
PKFKMPSFGVSAPGK

AHNAK2

836

Q8IVF2
PKFKMPSFGVSAPGK

AHNAK2

1001

Q8IVF2
PKFKMPSFGVSAPGK

AHNAK2

1331

Q8IVF2
PKFKMPSFGVSAPGK

AHNAK2

1496

Q8IVF2
PKFKMPSFGVSAPGK

AHNAK2

1661

Q8IVF2
PKFKMPSFGVSAPGK

AHNAK2

1826

Q8IVF2
PKFKMPSFGVSAPGR

AHNAK2

1991

Q8IVF2
PKFKMPSFGVSAPGK

AHNAK2

2156

Q8IVF2
PKFKMPSFGVSAPGK

AHNAK2

2486

Q8IVF2
PKFKMPSFGVSAPGK

AHNAK2

2816

Q8IVF2
PKFKMPSFGVSAPGK

AHNAK2

2981

Q8IVF2
PKFKMPSFGVSAPGK

AHNAK2

3146

Q8IVF2
PKFKMPSFGVSAPGR

AHNAK2

3476

Q8IVF2
PKFKMPSFGVSAPGK

AHNAK2

3806

Q8IVF2
PKFKMPSFGVSAPGK

AHNAK2

3971

Q8IVF2
PKFKMPSFGVSAPGK

AHNAK2

4136

Q8IVF2
PKFKMPSFGVSAPGK

AHNAK2

4301

Q8IVF2
KPADGKTIGMLVPSP

ZCCHC2

741

Q9C0B9
MAIPGGPKFEPLVRD

PRPF8

271

Q6P2Q9
NPFAKANGLPGKLMP

USP42

691

Q9H9J4
KGKEPGMALPQGRLT

ZNF578

11

Q96N58
KGMFPGEQFKPARRP

AGPAT3

291

Q9NRZ7
VGQMDKIFKIPPPPG

TEP1

856

Q99973
RNGIPKLTPGDNPYM

SPATS1

196

Q496A3
RPVDGLPPFKMEKTG

TRPV1

456

Q8NER1
PVGGKAKSPMFPALG

WASHC2C

1141

Q9Y4E1
FNPEGKALPPMRGFK

GTF3C4

151

Q9UKN8
PSGVFDGMPPNLKNL

TLR7

666

Q9NYK1
NPKPFLNGLTGKPVM

SNRPF

6

P62306
PKEVLFLGMNPGPFG

SMUG1

76

Q53HV7
RMKLLLGKDFPASPP

UBE2S

61

Q16763
RPGIDPQEKSPGKMS

ZNF264

141

O43296
PPVGGKAKSPMFPAL

WASHC2A

1161

Q641Q2
GNPPGTPKGKRELMS

ZNF608

631

Q9ULD9
KGKEPGMALPQGRLT

ZNF611

11

Q8N823
PQDRMKDPTFLGKLP

TASOR2

226

Q5VWN6
LGPKKNRALPFVPMS

GTF3C1

1486

Q12789
PTLPLPMEGFEEKKG

HIVEP2

2251

P31629
KEMFPGFRLALPPKR

SNX16

156

P57768
MRLKIGKGTGPPSPT

VASH1

301

Q7L8A9
VDQIIMAKPAGGPKP

CCT8

521

P50990
PGPGKVEGKAEPAMR

TXNRD3NB

106

Q6F5E7
PKRALPFRKGPNFTM

ZFHX3

1521

Q15911
QPPGPFDEQIRKLMG

UTF1

131

Q5T230
RPAGKGRDEPNMNPK

MYOF

1981

Q9NZM1