Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
DomainSushi

PAPPA2 MASP1 SEZ6L2 IL2RA F13B

6.14e-0752595PF00084
DomainCCP

PAPPA2 MASP1 SEZ6L2 IL2RA F13B

7.43e-0754595SM00032
DomainSUSHI

PAPPA2 MASP1 SEZ6L2 IL2RA F13B

8.93e-0756595PS50923
DomainSushi_SCR_CCP_dom

PAPPA2 MASP1 SEZ6L2 IL2RA F13B

9.77e-0757595IPR000436
DomainRBD

ARAF TIAM2

2.04e-047592SM00455
DomainRBD_dom

ARAF TIAM2

2.04e-047592IPR003116
DomainRBD

ARAF TIAM2

2.04e-047592PS50898
DomainCUB

MASP1 LRP3 SEZ6L2

4.98e-0449593PF00431
DomainCUB

MASP1 LRP3 SEZ6L2

5.28e-0450593SM00042
Domain-

MASP1 LRP3 SEZ6L2

5.93e-04525932.60.120.290
DomainCUB

MASP1 LRP3 SEZ6L2

6.27e-0453593PS01180
DomainCUB_dom

MASP1 LRP3 SEZ6L2

7.76e-0457593IPR000859
DomainPLAC

ADAMTS19 PAPLN

8.71e-0414592PF08686
DomainPLAC

ADAMTS19 PAPLN

1.62e-0319592PS50900
DomainPLAC

ADAMTS19 PAPLN

1.62e-0319592IPR010909
DomainADAM_spacer1

ADAMTS19 PAPLN

2.38e-0323592IPR010294
DomainADAM_spacer1

ADAMTS19 PAPLN

2.38e-0323592PF05986
DomainPeptidase_M12B_ADAM-TS

ADAMTS19 PAPLN

2.59e-0324592IPR013273
Pubmed

Crystallization and preliminary crystallographic studies of the NCoA-1/SRC-1 PAS-B domain bound to the LXXLL motif of the STAT6 transactivation domain.

NCOA1 STAT6

3.13e-06262214993689
Pubmed

Dec2 promotes Th2 cell differentiation by enhancing IL-2R signaling.

IL2RA STAT6

9.37e-06362219880450
Pubmed

An LXXLL motif in the transactivation domain of STAT6 mediates recruitment of NCoA-1/SRC-1.

NCOA1 STAT6

9.37e-06362212138096
Pubmed

Functional interaction between the p160 coactivator proteins and the transcriptional enhancer factor family of transcription factors.

TEAD2 NCOA1

9.37e-06362210934189
Pubmed

Structure of the NCoA-1/SRC-1 PAS-B domain bound to the LXXLL motif of the STAT6 transactivation domain.

NCOA1 STAT6

9.37e-06362214757047
Pubmed

Transcriptional activation by STAT6 requires the direct interaction with NCoA-1.

NCOA1 STAT6

9.37e-06362211574547
Pubmed

P160/SRC/NCoA coactivators form complexes via specific interaction of their PAS-B domain with the CID/AD1 domain.

NCOA1 STAT6

1.87e-05462218267973
Pubmed

Ras induces experimental lung metastasis through up-regulation of RbAp46 to suppress RECK promoter activity.

RBBP7 RECK

1.87e-05462225885317
Pubmed

IL13-Mediated Dectin-1 and Mannose Receptor Overexpression Promotes Macrophage Antitumor Activities through Recognition of Sialylated Tumor Cells.

MRC1 STAT6

4.67e-05662230610060
Pubmed

The transcriptional co-activator protein p100 recruits histone acetyltransferase activity to STAT6 and mediates interaction between the CREB-binding protein and STAT6.

NCOA1 STAT6

6.53e-05762215695802
Pubmed

ECM1 controls T(H)2 cell egress from lymph nodes through re-expression of S1P(1).

IL2RA STAT6

8.69e-05862221217760
Pubmed

IL-2 suppression of IL-12p70 by a recombinant HSV-1 expressing IL-2 induces T-cell auto-reactivity and CNS demyelination.

IL2RA STAT6

1.39e-041062221364747
Pubmed

Molecular patterning of the embryonic cranial mesenchyme revealed by genome-wide transcriptional profiling.

COLEC12 MASP1 AKAP12

1.63e-045962331351040
Pubmed

The transcription factor E4BP4 regulates the production of IL-10 and IL-13 in CD4+ T cells.

IL2RA STAT6

5.82e-042062221460847
Pubmed

Deficiency of STING Signaling in Embryonic Cerebral Cortex Leads to Neurogenic Abnormalities and Autistic-Like Behaviors.

SLC4A5 STAT6

7.06e-042262233304758
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

MYCL TEAD2 C2CD3 LRP3 PAPLN DHX34 TIAM2 PHC2

7.49e-04110562835748872
Pubmed

Identification of motif-based interactions between SARS-CoV-2 protein domains and human peptide ligands pinpoint antiviral targets.

NCOA1 NACAD AKAP12 STAT6

8.08e-0423362437704626
Pubmed

A directed protein interaction network for investigating intracellular signal transduction.

ZNF133 MASP1 YY1AP1 DHX34 NACAD TIAM2 AKAP12 PHC2

8.36e-04112462821900206
Pubmed

CTDP1 regulates breast cancer survival and DNA repair through BRCT-specific interactions with FANCI.

ARFGEF3 ARAF AKAP12

8.64e-0410462331240132
Pubmed

Recent acquisition of imprinting at the rodent Sfmbt2 locus correlates with insertion of a large block of miRNAs.

MRC1 IL2RA

1.07e-032762221510876
Pubmed

Genetic polymorphisms in adaptive immunity genes and childhood acute lymphoblastic leukemia.

IL2RA STAT6

1.23e-032962220716621
Pubmed

Voltage-gated potassium channel genes are clustered in paralogous regions of the mouse genome.

KCNB2 ARAF

1.41e-03316228034307
Pubmed

Quantitative interaction proteomics and genome-wide profiling of epigenetic histone marks and their readers.

TADA1 RBBP7 PHC2

1.43e-0312462320850016
GeneFamilyHyalectan proteoglycans|V-set domain containing|Sushi domain containing|C-type lectin domain containing

PAPPA2 MASP1 SEZ6L2 IL2RA F13B

2.89e-07574551179
CoexpressionGSE22886_IGM_MEMORY_BCELL_VS_BLOOD_PLASMA_CELL_UP

FRY C2CD3 RETREG1 MMRN2 NCOA1 RECK

7.45e-06198626M4451
ToppCellsevere_influenza-Treg|World / disease group, cell group and cell class (v2)

MRC1 HOXB2 APC2 IL2RA AQP3

2.07e-061496252a3a00cdf604c8f3f3863df0ddb06938549bf86d
ToppCell3'-Pediatric_IBD-SmallIntestine-Epithelial-neuro-epithelial-L_cells_(PYY+)|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ARFGEF3 TBC1D30 ABCC8 KCNB2 NACAD

3.51e-06166625d96c562e1483adb4cdd817b68133f03356d7279b
ToppCellfacs-Large_Intestine-Distal-24m-Epithelial-enteroendocrine_cell|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PAPPA2 ACSL6 ABCC8 KCNB2 SEZ6L2

5.50e-06182625398ce074a04f6482470b488f1affae4af7d2ec58
ToppCellfacs-Large_Intestine-Distal-3m-Epithelial-enteroendocrine_cell|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PAPPA2 ACSL6 ABCC8 KCNB2 SEZ6L2

5.80e-061846253da93e7d8b62463e307cc0425c47dbd3bef66799
ToppCelldroplet-Kidney-nan-18m-Epithelial-Pecam____Kidney_cortex_artery_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADRA2C MMRN2 KCNB2 RECK INSYN2A

6.28e-06187625e93cad16a087d1443cbf4e1690dc1b35d7a84c41
ToppCellILEUM-inflamed-(7)_Endothelial_cell-(7)_Lymphatics|(7)_Endothelial_cell / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

MRC1 COLEC12 RCSD1 RECK AKAP12

7.14e-06192625d43caf42ec744e895137f31ef65a990e250669d2
ToppCell(3)_Chondrocytes-(30)_Chondro|(3)_Chondrocytes / Cell class and subclass of bone marrow stroma cells in homeostatis

PAPPA2 COLEC12 MMRN2 RECK AKAP12

7.69e-06195625f5597d3ed37770c6fa2b339f98a80ac7ecd4f9ff
ToppCellEndothelial_cells-Endothelial-B|Endothelial_cells / lung cells shred on cell class, cell subclass, sample id

MRC1 COLEC12 PAPLN AKAP12 PGM5

7.89e-0619662536f95f9ef74eb951e41ef46fd136ceaef45208fc
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

RETREG1 SLC47A1 PAPLN SEZ6L2 AKAP12

8.28e-06198625be305d89d48c67ce922fa71aaf15e24d00c89ff6
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

RETREG1 SLC47A1 PAPLN SEZ6L2 AKAP12

8.70e-06200625105564ee05bd11685b5747ee32d5350cf3c2e2e1
ToppCell368C-Lymphocytic-NK_cells-NK_cell_C|NK_cells / Donor, Lineage, Cell class and subclass (all cells)

IL2RA AQP3 STAT6

2.96e-0543623edb371157503e0ce7c578a5920a35294aca2afc7
ToppCellLPS-antiTNF-Epithelial_alveolar-Mes-Like-Differentiating_AT1|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PLEKHG4B WDR91 MASP1 TIAM2

3.07e-051286242cf0384240a4a663869cf6b27d954236f6214a9a
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

MASP1 PAPLN CCDC168 AKAP12

6.97e-05158624e7db0ee4740e3c7a4d97d7cd7462e2c2ab458a4b
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell-Parietal_Epithelial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

MASP1 PAPLN CCDC168 AKAP12

6.97e-05158624d39e020c3e77eb9d3de600a171d22f94357061d4
ToppCellFetal_29-31_weeks-Epithelial-lung_neuroendocrine_cell_(PNEC)-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

ARFGEF3 RETREG1 KCNB2 SEZ6L2

7.14e-051596247747cef94c55144fddcd024a7495318357f1351b
ToppCellNS-critical-d_16-33-Myeloid-Mast_cell|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

PLEKHG4B HOXB2 SLC47A1 AKAP12

7.32e-05160624c61869d9dbba250270e59366e15af204e5b4395d
ToppCellMild-MAIT|Mild / Disease group and Cell class

COLEC12 TEAD2 FRY AQP3

7.50e-051616240c1a04485708d5302600cdc2d7dac1cb76b4033a
ToppCellmild-Myeloid-Eosinophils|mild / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

FRY SSH2 RAB44 AKAP12

7.86e-051636247c57d541a88e9afa079e95b8a6ecdea60a0c6aaa
ToppCell5'-GW_trimst-2-SmallIntestine-Epithelial-neuro-epithelial-K_cells_(GIP+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ARFGEF3 ABCC8 KCNB2 SEZ6L2

8.44e-05166624afba41e15478053f11815acf568d29187de75492
ToppCellmild_COVID-19_(asymptomatic)-CD4+_T_naive|mild_COVID-19_(asymptomatic) / disease group, cell group and cell class (v2)

RETREG1 SEZ6L2 AQP3 SLC4A5

8.64e-0516762478d264af390bd89942ffbb2991dc94f50756d4c9
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid-Macrophage_Dendritic-M2_Macrophage|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

MRC1 COLEC12 RCSD1 IL2RA

8.84e-0516862461a5435b27b01ff1a509ea463a6af220c5d2c9b3
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid-Macrophage_Dendritic|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

MRC1 COLEC12 RCSD1 IL2RA

8.84e-0516862426fce414439ccd204e3acb41f2b4f75072df5a26
ToppCell10x5'-lymph-node_spleen-Myeloid_Dendritic-pDC|lymph-node_spleen / Manually curated celltypes from each tissue

MYCL SLC47A1 PAPLN INSYN2A

8.84e-05168624cfed36fece51871a5abbcde71f6bd5e7212357ff
ToppCell3'-GW_trimst-2-LargeIntestine-Mesenchymal-immature_mesenchymal_cell-Mesoderm_1_(HAND1+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PLEKHG4B PAPPA2 TTC1 TIAM2

9.04e-051696243f738fc56bbc70dc77c9ba41025631f8264cd2b3
ToppCellE17.5-Mesenchymal-developing_mesenchymal_cell-mesenchymal_immature_unknown_1|E17.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

COLEC12 MMRN2 AKAP12 PGM5

9.25e-051706247fa022471e14ac8a3bc147c793368a4d56a8e591
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Endothelial-lymphatic_endothelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

MRC1 COLEC12 VSIG10L2 PGM5

9.25e-051706246035c92cd39c5ac54e7ec57d94888ee19f574639
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_medulla|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

MRC1 COLEC12 VSIG10L2 PGM5

9.25e-05170624c8c42eda44b61440c96b202e7f54650046eb95d3
ToppCell5'-GW_trimst-2-LargeIntestine-Epithelial-neuro-epithelial-L_cells_(PYY+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PAPPA2 ARFGEF3 ABCC8 KCNB2

9.25e-051706246a98f47f8c2b5b15e09169bd82eff1e6bf76e5a6
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_medulla-lymphatic_endothelial_cell_of_renal_medulla|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

MRC1 COLEC12 VSIG10L2 PGM5

9.25e-05170624dcc64b73134e89ae37990d4878813b86ce91dae9
ToppCell3'-Child09-12-SmallIntestine-Epithelial-neuro-epithelial-N_cells_(NTS+)|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ARFGEF3 TBC1D30 ABCC8 KCNB2

9.25e-0517062402f0be0aab8ba2d35a83238609352ef3677511c9
ToppCellsevere-Myeloid-Eosinophils|severe / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

FRY IL2RA RAB44 AKAP12

9.25e-05170624863f0266d5837cdbc3e09a3fe6a99dd3e6261674
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PAPPA2 WDR91 RETREG1 SEZ6L2

9.68e-051726240c2d0bb767e5ce089b42ad49e8b303a103de2d5c
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PAPPA2 WDR91 RETREG1 SEZ6L2

9.68e-05172624eeed177a03c116e9815a8e086d24efc9643b16a4
ToppCellfacs-Pancreas-Exocrine-3m-Epithelial-pancreatic_acinar_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TEAD2 RETREG1 DHX34 SLC4A5

9.90e-05173624c62e3ffed55bbb00dcaef6da0aab8446f3f55085
ToppCell5'-Adult-LargeIntestine-Endothelial-lymphatic_endothelial-LEC3_(ADGRG3+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MRC1 COLEC12 AKAP12 PGM5

9.90e-051736247dc988fc0ba29990567bf1bcdeb3faeeee507eb1
ToppCellfacs-Pancreas-Exocrine-3m-Epithelial-pancreatic_acinar_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TEAD2 RETREG1 DHX34 SLC4A5

9.90e-05173624f612d4ea9ab8dcde475f4118bca3e49be786e7fa
ToppCellEndothelial-B-Donor_03|World / lung cells shred on cell class, cell subclass, sample id

PAPLN RECK AKAP12 PGM5

9.90e-05173624a81992965137195d20fc498f750975303961a828
ToppCell3'-GW_trimst-2-SmallIntestine-Epithelial-neuro-epithelial-K_cells_(GIP+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ARFGEF3 ABCC8 KCNB2 SEZ6L2

1.06e-04176624d54543510c804474c5c32e007cd699e75fc5aaba
ToppCelldroplet-Liver-Npc-18m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MRC1 HOXB2 ADRA2C MMRN2

1.06e-041766243494ffa8555e6edf4b1250e10434bae9b73ec845
ToppCell3'-Pediatric_IBD-SmallIntestine-Epithelial-neuro-epithelial|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ARFGEF3 ABCC8 KCNB2 SEZ6L2

1.06e-04176624fb718a6b07aa5d56600263280afa530bcb63db42
ToppCelldroplet-Liver-Npc-18m-Endothelial|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MRC1 HOXB2 ADRA2C MMRN2

1.06e-04176624d43f6b7828b98e1dab7b726a5f99499d65a7db80
ToppCell3'-Parenchyma_lung-Endothelial-Blood_vessel_EC-pulmonary_artery_endothelial_cell-EC_arterial-EC_arterial_L.2.4.1.3|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TEAD2 FRY MMRN2 CCDC9

1.08e-0417762416197068260fc062bf8b730a51a199887ea580b9
ToppCell3'-GW_trimst-1.5-SmallIntestine-Epithelial-neuro-epithelial-M/X_cells_(MLN/GHRL+)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ARFGEF3 ABCC8 KCNB2 SEZ6L2

1.08e-04177624c80893e5cf5688ee9f5afc8f11b3890f296c9e1f
ToppCell10x5'-GI_large-bowel-Lymphocytic_T_CD4-Trm_Th1/Th17|GI_large-bowel / Manually curated celltypes from each tissue

ACSL6 FRY IL2RA AQP3

1.13e-041796246359f30005b17dc5b5c4c8f3a6a38c87ccfe4ee9
ToppCellCOVID-19-Heart-Lymph_EC|Heart / Disease (COVID-19 only), tissue and cell type

MRC1 COLEC12 AKAP12 PGM5

1.13e-04179624411620201a860716a8773b92f50f7b94ef34a586
ToppCellsevere-Myeloid-Eosinophils|Myeloid / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

FRY IL2RA RAB44 AKAP12

1.15e-04180624ac03812b1409435c55d323a7516deeac82bd3509
ToppCell5'-GW_trimst-2-SmallIntestine-Epithelial-neuro-epithelial-M/X_cells_(MLN/GHRL+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ARFGEF3 ABCC8 KCNB2 SEZ6L2

1.18e-04181624cb17c904ab86d56dd30cac9b61acbb3b76f84ded
ToppCellfacs-Brain_Non-Myeloid-Cerebellum_-18m|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FRY MMRN2 RECK AKAP12

1.20e-04182624ef65b095f4240d61cfd4a59aec19d72d324dba1d
ToppCellfacs-Brain_Non-Myeloid-Cerebellum_|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FRY MMRN2 RECK AKAP12

1.20e-0418262497a805783a1f2b055c21307db250e3688674eff3
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_cortex|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

MRC1 COLEC12 RCSD1 PGM5

1.20e-0418262441b070085edba7a58b81c20aa4942d06f745acf8
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_cortex-lymphatic_endothelial_cell_of_renal_cortex|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

MRC1 COLEC12 RCSD1 PGM5

1.20e-041826245e9a67b2de0daa4fdc344b10a857d8a901ad810e
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Endothelial-lymphatic_endothelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

MRC1 COLEC12 RCSD1 PGM5

1.20e-04182624b0fe042c71d6ab8c75abd7ba9d2de00b72d01c0c
ToppCelldroplet-Liver-Npc-21m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MRC1 HOXB2 MMRN2 PGM5

1.20e-04182624b1ec2015aad1181eac1bbf8d48ad6f2f7ed24a01
ToppCellsevere-Myeloid-Neutrophils_1|severe / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

FRY SSH2 DHX34 PHC2

1.23e-0418362460a6112aa4fc4f5debda4c7e81b37539ba2e4e6e
ToppCellwk_15-18-Epithelial-Proximal_epithelial-GHRL+_neuroendocrine|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

ARFGEF3 ABCC8 KCNB2 SEZ6L2

1.23e-041836248820cfed27b292bc0bc9cde4005219ed41900552
ToppCell3'-Adult-LargeIntestine-Epithelial-neuro-epithelial-L_cells_(PYY+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PAPPA2 ABCC8 KCNB2 NACAD

1.23e-0418362449f3ddc1c7c04b4ca837dbd6dad995add82941d6
ToppCellfacs-Mammary_Gland-Mammary_Gland-3m-Epithelial-luminal_epithelial_cell_of_mammary_gland|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYCL ARFGEF3 TEAD2 ABCC8

1.23e-041836247eaa6ef7c6cf848fd6489f97677f4406318da22f
ToppCelldroplet-Kidney-KIDNEY-1m-Epithelial-Epcam____podocyte-2|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HOXB2 ADRA2C AKAP12 PGM5

1.25e-04184624e123ad8ee46a032825a0bd4b3586ddcb3eda03d4
ToppCellCOPD-Myeloid-Macrophage_Alveolar|World / Disease state, Lineage and Cell class

MRC1 COLEC12 SLC47A1 AQP3

1.25e-041846247fd0b227c3750ffb80e41e92c60fcce46656be14
ToppCell3'-Child04-06-SmallIntestine-Mesenchymal-myocytic-myofibroblast_(RSPO2+)|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MASP1 NACAD VSIG10L2 AKAP12

1.25e-04184624590fb32bb1f348ea5fa2aece30ebe1e212512991
ToppCellfacs-Large_Intestine-Proximal-24m-Epithelial-enteroendocrine_cell|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PAPPA2 ABCC8 KCNB2 SEZ6L2

1.28e-041856242a8104f610fa5ce618f8105521616722462a0d42
ToppCellfacs-Brain_Non-Myeloid-Cerebellum_-18m-Endothelial-Endothelial_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FRY MMRN2 RECK AKAP12

1.31e-04186624ba6ba75218efc26371cea24ddbb0e9b3e3f421ac
ToppCellfacs-Brain_Non-Myeloid-Cerebellum_-18m-Endothelial|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FRY MMRN2 RECK AKAP12

1.31e-0418662465e25a9dcef5fc71510aaf170e220deef5b2feb2
ToppCellfacs-Brain_Non-Myeloid-Cerebellum_-18m-Endothelial-endothelial_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FRY MMRN2 RECK AKAP12

1.31e-04186624e4f1259725160719e5fd13d76e5a707efed70013
ToppCell3'_v3-bone_marrow-Lymphocytic_T_CD4-Tregs|bone_marrow / Manually curated celltypes from each tissue

HOXB2 RETREG1 IL2RA AQP3

1.34e-04187624bda716a64262325e6e68b281caf131f1840fd298
ToppCelldroplet-Lung-LUNG-30m-Mesenchymal|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COLEC12 HOXB2 SLC47A1 AKAP12

1.34e-04187624976b74d081b7fba8620768613cc26f9262cd7b16
ToppCell5'-Adult-LargeIntestine-Mesenchymal-fibroblastic-Stromal_2_(NPY+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PAPPA2 COLEC12 PAPLN INSYN2A

1.36e-04188624997dcfc4f08738ab398d8abc15e4fd2fc6619862
ToppCellfacs-Pancreas-Endocrine-24m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ARFGEF3 ABCC8 NCOA1 SEZ6L2

1.36e-04188624a91443aa8fa8fa87f7501c59219daa0305bd0bbf
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

RETREG1 SLC47A1 PAPLN AKAP12

1.39e-041896243b48b0d220cc24d5170713d61fa91f5bb6c21841
ToppCellGlobus_pallidus-Endothelial|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

TEAD2 RCSD1 PGM5 STAT6

1.39e-04189624ad7dc9d25edd68fb624380a082c389fe7d640e7d
ToppCellStriatum-Endothelial|Striatum / BrainAtlas - Mouse McCarroll V32

COLEC12 RCSD1 RECK PGM5

1.39e-0418962495ee3b6d7fbbfcf91c780dfcd0926acec05f0a2d
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

RETREG1 SLC47A1 PAPLN KCNB2

1.39e-0418962428b502611829e4a24caff2562545c7db97686099
ToppCellfacs-Thymus-Flowthrough-24m-Mesenchymal-fibroblast|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PAPPA2 HOXB2 RECK TIAM2

1.42e-04190624990ac07f4b0a22041daac7502f74fafd6d258cba
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid-Macrophage_Dendritic-M2_Macrophage|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

MRC1 COLEC12 RCSD1 IL2RA

1.42e-04190624788ff9d8888d2dd25b7e1d7e0e5d57751ce86f19
ToppCellfacs-Thymus-Flowthrough-24m-Mesenchymal-fibroblast|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PAPPA2 HOXB2 RECK TIAM2

1.42e-04190624fc9bbe5e6e0ec3cfa47bf479d8b09a0fc53169cc
ToppCelldroplet-Lung-18m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell-pulmonary_artery_endothelial_cell_l27|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

TEAD2 ADRA2C MMRN2 PGM5

1.42e-041906243cf464664d6aa22b212e60b70885953887e92483
ToppCellfacs-Thymus-Flowthrough-24m-Mesenchymal|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PAPPA2 HOXB2 RECK TIAM2

1.42e-0419062439ecdf8815e235771132684dfc1aff1917e20965
ToppCellLV-08._Macrophage|World / Chamber and Cluster_Paper

MRC1 COLEC12 RCSD1 IL2RA

1.45e-04191624e7a0bc46ba9ba772636a583f3387748418e18832
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid-Macrophage_Dendritic|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

MRC1 COLEC12 RCSD1 IL2RA

1.45e-04191624baa70781633a3fe5bf987f9d8dff3884f5167e7f
ToppCellBAL-Severe-Myeloid-TRAM-TRAM3|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

MRC1 COLEC12 RETREG1 SLC47A1

1.45e-041916242b10a73c5d80e83d67a7121fb004a1aa86a537ef
ToppCellBAL-Severe-Myeloid-TRAM-TRAM3-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

MRC1 COLEC12 RETREG1 SLC47A1

1.45e-0419162402e1ae144da7274171e055356d10e8d175c5347f
ToppCellfacs-Pancreas-Endocrine-24m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ARFGEF3 ABCC8 NCOA1 SEZ6L2

1.45e-041916243387b95a3f2445c672d407922fdce3a91eabaef8
ToppCellSevere_COVID-19-Myeloid-TRAM3|Severe_COVID-19 / Disease group,lineage and cell class (2021.01.30)

MRC1 COLEC12 RETREG1 SLC47A1

1.45e-0419162405867b96199a46a415848409130697c810d18937
ToppCellBAL-Severe-Myeloid-TRAM|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

MRC1 COLEC12 RETREG1 SLC47A1

1.45e-041916244c4f50a502e3f6768a89df686fa2830b83b8b33f
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c07-AHNAK|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

FRY RETREG1 DDX21 AQP3

1.45e-04191624e94dfd2d8da81bfd16f2f1a4f3ac27b078eeb3ca
ToppCellControl-Myeloid-Macrophage_Alveolar|Myeloid / Disease state, Lineage and Cell class

ZNF589 RETREG1 SLC47A1 AQP3

1.45e-04191624a7bb8aba9c59c037d995a77928cc7b4d5cbb82b9
ToppCellBAL-Severe-Myeloid-TRAM|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

MRC1 COLEC12 RETREG1 SLC47A1

1.45e-04191624de7c88bb46f794291025ef121a89fcd94dea4ffe
ToppCell367C-Endothelial_cells-Endothelial-F_(Lymphatics)|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)

MRC1 COLEC12 PAPLN RCSD1

1.48e-041926245e709c0714e8eba27e03a6def0544256bedb3ced
ToppCell368C-Endothelial_cells-Endothelial-F_(Lymphatics)|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)

MRC1 COLEC12 AKAP12 PGM5

1.48e-04192624b016e229300c183e14c0e2bba494bf49c7899112
ToppCellBAL-Severe-Myeloid-TRAM-TRAM3|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

MRC1 COLEC12 RETREG1 SLC47A1

1.48e-0419262434505a13b8a47c9286c560122fa7861b9c331a08
ToppCell5'-GW_trimst-2-SmallIntestine-Epithelial-neuro-epithelial|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ARFGEF3 ABCC8 KCNB2 SEZ6L2

1.48e-041926245692bd57093852d442400383850f416c497dcc7d
ToppCell368C-Endothelial_cells-Endothelial-F_(Lymphatics)-|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)

MRC1 COLEC12 AKAP12 PGM5

1.48e-04192624ac96831492c62ad9e1f7d0b764fbdf7d8a189ad9
ToppCellCOVID-19-lung-Lymphatic_EC|COVID-19 / Disease (COVID-19 only), tissue and cell type

MRC1 COLEC12 AKAP12 PGM5

1.48e-04192624cbe57cda44232b183821ac633b60a2668265e616
ToppCellBAL-Severe-Myeloid-TRAM-TRAM3-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

MRC1 COLEC12 RETREG1 SLC47A1

1.48e-0419262457c1410ebf90c230993e065eb78385daa3360960
ToppCellCOVID-19_Severe-CD4+_Tcm|World / disease group, cell group and cell class

ACSL6 RETREG1 IL2RA AQP3

1.48e-041926243352f13a6e706991dcf3ec173587bb6aba36a385
ToppCell367C-Endothelial_cells-Endothelial-F_(Lymphatics)-|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)

MRC1 COLEC12 PAPLN RCSD1

1.48e-041926245f4f44f15d3a2846981e68296643a4634930a211
ToppCellSevere-Myeloid-Macrophages-FABP4+|Severe / Condition, Lineage, Cell class and cell subclass

MRC1 COLEC12 RETREG1 SLC47A1

1.48e-0419262430aad927ad40d8abaf9d0539bf8cb9d88d16f24d
ToppCellPCW_10-12-Mesenchymal-Mesenchymal_myocytic-mes_pericyte_(14)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

MASP1 FRY ADRA2C RCSD1

1.48e-041926245000440dc1ed17e7474d340921bdff945646f27e
ToppCellCOVID-19-Myeloid-TRAM1|Myeloid / Condition, Lineage and Cell class

COLEC12 RETREG1 SLC47A1 AQP3

1.51e-041936246e6a7f4e50c8ae70bc187b9ce77140a7049dd288
ToppCellsevere-CD4+_Tcm|World / disease stage, cell group and cell class

ACSL6 RETREG1 DDX21 AQP3

1.51e-04193624be0370b2f0093ad0b9d876297bd196d0160f3d99
Drug17-AAG; Down 200; 1uM; HL60; HT_HG-U133A

MYCL TBC1D30 ZNF589 APBA3 DHX34 RECK

1.33e-051946161166_DN
DrugFenofibrate [49562-28-9]; Down 200; 11uM; MCF7; HT_HG-U133A

UBE2D4 ITFG2 RETREG1 NCOA1 DHX34 STAT6

1.37e-051956167432_DN
DrugBerberine chloride [633-65-8]; Down 200; 10.8uM; MCF7; HT_HG-U133A

MYCL WDR91 TBC1D30 UBE2D4 ITFG2 RETREG1

1.45e-051976166791_DN
DrugAcetaminophen [103-90-2]; Down 200; 26.4uM; MCF7; HT_HG-U133A

MYCL ZNF133 ITFG2 RETREG1 APBA3 AQP3

1.45e-051976163364_DN
DrugNeostigmine bromide [114-80-7]; Down 200; 13.2uM; MCF7; HT_HG-U133A

ADRA2C ITFG2 RETREG1 APBA3 CAMTA2 DHX34

1.50e-051986165335_DN
DrugSulfachloropyridazine [80-32-0]; Up 200; 14uM; MCF7; HT_HG-U133A

MYCL COLEC12 MMRN2 APBA3 IL2RA STAT6

1.54e-051996163944_UP
DrugCholecalciferol [67-97-0]; Down 200; 10.4uM; MCF7; HT_HG-U133A

UBE2D4 ITFG2 RETREG1 APBA3 SLC47A1 STAT6

1.54e-051996165002_DN
DrugSpironolactone [52-01-7]; Down 200; 9.6uM; PC3; HT_HG-U133A

MYCL ITFG2 MMRN2 LRP3 DHX34 RECK

1.54e-051996165781_DN
DrugCytisine (-) [485-35-8]; Down 200; 21uM; MCF7; HT_HG-U133A

WDR91 TBC1D30 ZNF589 LRP3 NCOA1 DHX34

1.58e-052006162759_DN
DrugDicloxacillin sodium salt [13412-64-1]; Down 200; 8.2uM; MCF7; HT_HG-U133A

ZNF133 ITFG2 ZNF589 LRP3 SLC47A1 DHX34

1.58e-052006165012_DN
DrugFolinic acid calcium salt [6035-45-6]; Down 200; 7.8uM; MCF7; HT_HG-U133A

WDR91 ZNF589 APBA3 SLC47A1 CAMTA2 CCDC9

1.58e-052006163442_DN
DrugHydrocotarnine hydrobromide [5985-00-2]; Down 200; 13.2uM; PC3; HT_HG-U133A

TBC1D30 UBE2D4 ITFG2 MMRN2 DHX34 CCDC9

1.58e-052006164489_DN
DrugClenbuterol hydrochloride [21898-19-1]; Up 200; 12.8uM; PC3; HT_HG-U133A

APC2 ZNF589 AQP3 AKAP12 STAT6

8.78e-051686154671_UP
DrugAlprostadil [745-65-3]; Down 200; 11.2uM; HL60; HT_HG-U133A

FRY TBC1D30 ZNRD2 LRP3 DDX21

1.06e-041756152938_DN
DrugThiostrepton [1393-48-2]; Down 200; 2.4uM; HL60; HT_HG-U133A

FRY C2CD3 ITFG2 RETREG1 RECK

1.12e-041776152462_DN
DrugChrysin [480-40-0]; Down 200; 15.8uM; HL60; HT_HG-U133A

TBC1D30 UBE2D4 ZNF589 NCOA1 STAT6

1.25e-041816153106_DN
DrugFenoterol hydrobromide [1944-12-3]; Up 200; 10.4uM; PC3; HT_HG-U133A

PAPPA2 TBC1D30 APC2 AQP3 AKAP12

1.28e-041826156331_UP
DrugTerbutaline hemisulfate [23031-32-5]; Up 200; 7.2uM; PC3; HT_HG-U133A

HOXB2 TBC1D30 ITFG2 AQP3 AKAP12

1.31e-041836155764_UP
DrugHelveticoside [630-64-8]; Down 200; 7.4uM; HL60; HT_HG-U133A

ZNF133 C2CD3 TBC1D30 ZNF589 NCOA1

1.42e-041866152192_DN
DrugICI 182,780; Down 200; 1uM; MCF7; HT_HG-U133A

PAPPA2 ZNF589 LRP3 APBA3 DHX34

1.49e-041886155565_DN
DrugPromazine hydrochloride [53-60-1]; Down 200; 12.4uM; MCF7; HT_HG-U133A

TBC1D30 ITFG2 RETREG1 AQP3 DHX34

1.56e-041906153927_DN
Drug16-phenyl tetranor Prostaglandin E2; Up 200; 10uM; PC3; HT_HG-U133A

MYCL ITFG2 AQP3 CCDC9 AKAP12

1.56e-041906157546_UP
Drug11-deoxy-16,16-dimethyl Prostaglandin E2; Up 200; 10uM; PC3; HT_HG-U133A

TBC1D30 LRP3 AQP3 CCDC9 AKAP12

1.60e-041916157538_UP
Drugretinoic acid; Down 200; 1uM; MCF7; HT_HG-U133A_EA

RETREG1 LRP3 NCOA1 CAMTA2 AQP3

1.60e-04191615991_DN
Drugtrichostatin A; Up 200; 0.1uM; PC3; HG-U133A

WDR91 ZNRD2 RETREG1 KCNB2 AQP3

1.60e-04191615448_UP
DrugFenbufen [36330-85-5]; Down 200; 15.8uM; MCF7; HT_HG-U133A

UBE2D4 ITFG2 SLC47A1 AQP3 AKAP12

1.64e-041926154743_DN
DrugAcacetin [480-44-4]; Down 200; 14uM; MCF7; HT_HG-U133A

PAPPA2 ITFG2 RETREG1 NCOA1 AKAP12

1.64e-041926156044_DN
DrugPF-00562151-00 [351320-12-2]; Up 200; 10uM; PC3; HT_HG-U133A

PAPPA2 TBC1D30 ITFG2 ZNF589 NACAD

1.68e-041936155922_UP
DrugCetirizine dihydrochloride [83881-52-1]; Up 200; 8.6uM; MCF7; HT_HG-U133A

ITFG2 MMRN2 SEZ6L2 CCDC9 STAT6

1.68e-041936152829_UP
DrugOxalamine citrate salt [1949-20-8]; Up 200; 9.2uM; MCF7; HT_HG-U133A

MYCL COLEC12 FRY ZNF589 DHX34

1.68e-041936153344_UP
Drug(-) -Levobunolol hydrochloride [27912-14-7]; Down 200; 12.2uM; MCF7; HT_HG-U133A

MYCL TBC1D30 ITFG2 APBA3 CCDC9

1.72e-041946154134_DN
DrugCyclizine hydrochloride [303-25-3]; Down 200; 13.2uM; MCF7; HT_HG-U133A

MYCL PAPPA2 TBC1D30 UBE2D4 CAMTA2

1.72e-041946152880_DN
DrugHydroxyzine dihydrochloride [2192-20-3]; Down 200; 9uM; PC3; HT_HG-U133A

MYCL TBC1D30 ITFG2 MMRN2 DHX34

1.72e-041946156660_DN
Drug9-deoxy-9-methylene-16,16-dimethyl Prostaglandin E2; Up 200; 10uM; PC3; HT_HG-U133A

ITFG2 ZNF589 NCOA1 AQP3 CCDC9

1.77e-041956157504_UP
DrugSulfamerazine [127-79-7]; Down 200; 15.2uM; PC3; HT_HG-U133A

HOXB2 TBC1D30 ITFG2 RETREG1 DHX34

1.77e-041956153718_DN
DrugCephapirin sodium salt [24356-60-3]; Down 200; 9uM; MCF7; HT_HG-U133A

TBC1D30 UBE2D4 APBA3 CAMTA2 AQP3

1.81e-041966153471_DN
Drug2-propylpentanoic acid; Up 200; 500uM; MCF7; HG-U133A

MASP1 ZNF589 IL2RA AKAP12 STAT6

1.81e-04196615347_UP
DrugPantothenic acid calcium salt monohydrate [63409-48-3]; Down 200; 8uM; MCF7; HT_HG-U133A

MYCL PAPPA2 ZNF589 AQP3 STAT6

1.81e-041966153248_DN
DrugPhentolamine hydrochloride [73-05-2]; Down 200; 12.6uM; MCF7; HT_HG-U133A

PAPPA2 ZNF589 SLC47A1 AQP3 DHX34

1.81e-041966153971_DN
Drug2-propylpentanoic acid; Down 200; 1000uM; MCF7; HT_HG-U133A

HOXB2 RETREG1 APBA3 AQP3 DHX34

1.81e-041966155569_DN
DrugPyrithyldione [77-04-3]; Down 200; 24uM; MCF7; HT_HG-U133A

MYCL UBE2D4 RETREG1 AQP3 CCDC9

1.81e-041966153482_DN
DrugOxprenolol hydrochloride [6452-73-9]; Up 200; 13.2uM; MCF7; HT_HG-U133A

RETREG1 SLC47A1 AQP3 DHX34 AKAP12

1.81e-041966157225_UP
DrugTestosterone propionate [57-85-2]; Down 200; 11.6uM; MCF7; HT_HG-U133A

ITFG2 ZNF589 NCOA1 APBA3 AQP3

1.81e-041966155636_DN
DrugMimosine [500-44-7]; Down 200; 20.2uM; PC3; HT_HG-U133A

TBC1D30 ITFG2 ZNF589 MMRN2 LRP3

1.81e-041966156703_DN
DrugPNU-0251126 [267429-19-6]; Down 200; 10uM; MCF7; HT_HG-U133A

MYCL WDR91 ZNF589 RETREG1 APBA3

1.81e-041966154711_DN
Drug5151277; Down 200; 14uM; MCF7; HT_HG-U133A_EA

WDR91 ZNF133 RETREG1 APBA3 AQP3

1.81e-04196615903_DN
DrugMethoxamine hydrochloride [61-16-5]; Down 200; 16.2uM; MCF7; HT_HG-U133A

PAPPA2 WDR91 ITFG2 AQP3 CCDC9

1.81e-041966154972_DN
DrugGramine [87-52-5]; Up 200; 23uM; PC3; HT_HG-U133A

HOXB2 MASP1 RETREG1 SLC4A5 CCDC9

1.81e-041966153999_UP
DrugBaclofen (R,S) [1134-47-0]; Up 200; 18.8uM; HL60; HG-U133A

PAPPA2 COLEC12 ITFG2 KCNB2 SLC4A5

1.81e-041966152036_UP
DrugPNU-0251126 [267429-19-6]; Up 200; 1uM; MCF7; HT_HG-U133A

PAPPA2 HOXB2 ZNF589 AQP3 CCDC9

1.81e-041966154714_UP
DrugLeucomisine [17946-87-1]; Down 200; 16.2uM; HL60; HT_HG-U133A

ZNF133 TBC1D30 UBE2D4 ZNF589 RETREG1

1.85e-041976156125_DN
DrugHydrastine hydrochloride [5936-28-7]; Down 200; 9.6uM; HL60; HG-U133A

ITFG2 ZNF589 RETREG1 APBA3 RECK

1.85e-041976151740_DN
DrugIfosfamide [3778-73-2]; Down 200; 15.4uM; MCF7; HT_HG-U133A

MYCL ZNF133 UBE2D4 NCOA1 APBA3

1.85e-041976156279_DN
DrugTriflusal [322-79-2]; Down 200; 16.2uM; HL60; HG-U133A

WDR91 ITFG2 RETREG1 CAMTA2 RECK

1.85e-041976151717_DN
DrugBuspirone hydrochloride [33386-08-2]; Down 200; 9.4uM; MCF7; HT_HG-U133A

WDR91 C2CD3 AQP3 AKAP12 STAT6

1.85e-041976155343_DN
DrugCefepime hydrochloride [123171-59-5]; Up 200; 7.4uM; PC3; HT_HG-U133A

HOXB2 MASP1 RETREG1 SLC47A1 DHX34

1.85e-041976155761_UP
DrugCefotiam hydrochloride; Down 200; 7.2uM; MCF7; HT_HG-U133A

C2CD3 ITFG2 RETREG1 NCOA1 DHX34

1.85e-041976155361_DN
DrugSuccinylsulfathiazole [116-43-8]; Up 200; 11.2uM; MCF7; HT_HG-U133A

PAPPA2 ABCC8 ZNF589 MMRN2 PHC2

1.85e-041976152821_UP
DrugChlortetracycline hydrochloride [64-72-2]; Down 200; 7.8uM; MCF7; HT_HG-U133A

MYCL ZNF589 RETREG1 AQP3 DHX34

1.85e-041976151541_DN
DrugBucladesine sodium salt [16980-89-5]; Down 200; 7.8uM; MCF7; HT_HG-U133A

ZNF133 ITFG2 ZNF589 RETREG1 LRP3

1.90e-041986153483_DN
DrugFlupentixol dihydrochloride cis-(Z) [2413-38-9]; Up 200; 7.8uM; HL60; HT_HG-U133A

ZNF133 MASP1 UBE2D4 APBA3 DHX34

1.90e-041986151288_UP
DrugPNU-0230031 [267429-39-0]; Down 200; 1uM; MCF7; HT_HG-U133A

ITFG2 ZNF589 APBA3 AQP3 DHX34

1.90e-041986153632_DN
DrugCefoperazone dihydrate; Up 200; 5.8uM; PC3; HT_HG-U133A

PAPPA2 ITFG2 ZNF589 DHX34 RECK

1.90e-041986156323_UP
DrugPHA-00745360 [351320-33-7]; Up 200; 1uM; PC3; HT_HG-U133A

HOXB2 ZNF589 MMRN2 DHX34 STAT6

1.90e-041986154562_UP
DrugPHA-00851261E [724719-49-7]; Down 200; 10uM; MCF7; HT_HG-U133A

WDR91 ZNF133 HOXB2 SLC47A1 AKAP12

1.90e-041986153854_DN
DrugMetixene hydrochloride [1553-34-0]; Down 200; 11.6uM; MCF7; HT_HG-U133A

MYCL PAPPA2 WDR91 TBC1D30 NCOA1

1.90e-041986153313_DN
DrugBetulinic acid [472-15-1]; Down 200; 8.8uM; MCF7; HT_HG-U133A

MYCL UBE2D4 ITFG2 ZNF589 AQP3

1.90e-041986153281_DN
Drug(+,-)-Octopamine hydrochloride [770-05-8]; Down 200; 21uM; MCF7; HT_HG-U133A

PAPPA2 HOXB2 TBC1D30 SLC47A1 STAT6

1.94e-041996156491_DN
DrugOrnidazole [16773-42-5]; Down 200; 18.2uM; PC3; HT_HG-U133A

TBC1D30 UBE2D4 ZNF589 CAMTA2 DHX34

1.94e-041996152109_DN
DrugParbendazole [14255-87-9]; Down 200; 16.2uM; MCF7; HT_HG-U133A

PAPPA2 ZNF133 TBC1D30 ZNF589 RETREG1

1.94e-041996154357_DN
DrugFlurbiprofen [5104-49-4]; Down 200; 16.4uM; MCF7; HT_HG-U133A

MYCL HOXB2 SLC47A1 AQP3 DHX34

1.94e-041996155634_DN
DrugVidarabine [5536-17-4]; Down 200; 15uM; MCF7; HT_HG-U133A

MYCL LRP3 APBA3 CAMTA2 AQP3

1.94e-041996157203_DN
Drugprochlorperazine dimaleate salt; Down 200; 10uM; MCF7; HT_HG-U133A

ZNF589 RETREG1 CCDC9 AKAP12 STAT6

1.94e-041996155575_DN
DrugAcetopromazine maleate salt [3598-37-6]; Down 200; 9uM; MCF7; HT_HG-U133A

TBC1D30 UBE2D4 ZNF589 DHX34 CCDC9

1.94e-041996152769_DN
DrugNaproxen [22204-53-1]; Up 200; 17.4uM; HL60; HT_HG-U133A

PAPPA2 ITFG2 ZNF589 NCOA1 STAT6

1.99e-042006151869_UP
DrugFluorometholone [426-13-1]; Down 200; 10.6uM; MCF7; HT_HG-U133A

MYCL ITFG2 ZNF589 LRP3 STAT6

1.99e-042006156071_DN
DrugAmbroxol hydrochloride [23828-92-4]; Down 200; 9.6uM; MCF7; HT_HG-U133A

ADRA2C TBC1D30 ITFG2 RETREG1 NCOA1

1.99e-042006155319_DN
DrugPrednisone [53-03-2]; Up 200; 11.2uM; MCF7; HT_HG-U133A

MYCL ITFG2 ZNF589 AQP3 DHX34

1.99e-042006151478_UP
Drugtegafur

ADAMTS19 CHFR RECK

3.09e-0449613CID000005386
Diseasedescending aortic diameter

PAPPA2 MASP1 ABCC8 STAT6

3.38e-0588614EFO_0021788
DiseaseNeonatal diabetes mellitus

ABCC8 IL2RA

1.22e-0325612C0158981
Diseaseatopic eczema

ACSL6 IL2RA AQP3 STAT6

1.85e-03252614EFO_0000274
Diseaseinterleukin 2 receptor antagonist measurement

ZNF469 IL2RA

2.39e-0335612EFO_0008332
Diseaseasthma (implicated_via_orthology)

IL2RA STAT6

2.39e-0335612DOID:2841 (implicated_via_orthology)
DiseaseDiabetes Mellitus, Sudden-Onset

ABCC8 IL2RA

3.76e-0344612C4554117
DiseaseDiabetes Mellitus, Ketosis-Prone

ABCC8 IL2RA

3.76e-0344612C3837958
DiseaseDiabetes, Autoimmune

ABCC8 IL2RA

3.76e-0344612C0205734
DiseaseBrittle diabetes

ABCC8 IL2RA

3.76e-0344612C0342302
DiseaseDiabetes Mellitus, Insulin-Dependent

ABCC8 IL2RA

3.93e-0345612C0011854
Diseasebody weight

PAPPA2 ZNF133 ABCC8 ZNF589 CHFR KCNB2 TTC1 PHC2

4.29e-031261618EFO_0004338

Protein segments in the cluster

PeptideGeneStartEntry
AHPGEDAVPTGPDCQ

AKAP12

1466

Q02952
GENGHCAPPPADVEP

ADRA2C

271

P18825
PAPQEVPGPCDHEDL

APBA3

201

O96018
VPCQGPDAPPVQDEG

CAMTA2

661

O94983
PVSFDQPPEGSHLPC

RCSD1

141

Q6JBY9
VEPHDPDPNQEPGST

RAB44

461

Q7Z6P3
IVEEVTHPCNPNPCP

RECK

486

O95980
SPPPAQHAEPDGDEV

ADAMTS19

151

Q8TE59
PECSEQPSQTHTPPG

INSYN2A

316

Q6ZSG2
CVPLEDFGGQHPDPN

PGM5

256

Q15124
PADPGDSHQEPQDGP

MMRN2

141

Q9H8L6
PPECVENNENCKHPP

F13B

386

P05160
NEPTPAPEDNGCPPH

COLEC12

596

Q5KU26
APREPCSAQDPHPQV

LRP3

716

O75074
GEPVLSPQPCTDPDH

LMNTD2

336

Q8IXW0
HPDQPPQCAPSSLQD

ITFG2

431

Q969R8
HPAKPDPSGECNPDL

RBBP7

156

Q16576
QTQHREPPDGEPACP

HOXB2

201

P14652
GPPDVDQPCEPSLQA

PAPPA2

916

Q9BXP8
TPQGPSPRTQHCDPE

ARAF

181

P10398
EVPTHPEDGTPQPGN

APC2

256

O95996
RQAAQPPHCPAPEGE

CHFR

436

Q96EP1
QPHSHPNPDCQEKPE

KCNB2

551

Q92953
QPDEVQREGPSCPSP

C2CD3

2101

Q4AC94
PCSEQAHGVPFSPEE

CCDC9

461

Q9Y3X0
PECEGSPPEHSPEQG

ARFGEF3

1056

Q5TH69
VDQASLPGHCREPPP

IL2RA

116

P01589
AAGNECPELQPPVHG

MASP1

296

P48740
TEPVNPIVQHCDNPP

FRY

1501

Q5TBA9
SHEVGIPVDQPPCSE

CCDC168

3231

Q8NDH2
KNGFPHPEPDCNPSE

DDX21

151

Q9NR30
HENTCPQAPQDGPPG

DHX34

1086

Q14147
TEPPQLPGRCPESDH

MRC1

1221

P22897
GQNPASHPPPDDAEQ

TADA1

241

Q96BN2
PPEHAEEGCPAPAAE

RETREG1

6

Q9H6L5
IHPPDEPGTENQEAC

NCOA1

201

Q15788
QHCPSPGAPPLESVD

TEAD2

256

Q15562
GPPNAIECVDPTEPH

SEZ6L2

501

Q6UXD5
SALPQDPLHPGCPEN

SLC47A1

486

Q96FL8
EEQCAPHEPTPQGPA

ABCC8

621

Q09428
VEDCGQENHQAPVPP

ACSL6

251

Q9UKU0
GCHLEQPPPSNEEEN

AQP3

266

Q92482
QQCHPPTPDTGPQNG

PHC2

421

Q8IXK0
PDVHPEAEQQPGPES

TIAM2

1601

Q8IVF5
SPPPVESEAAQSCHP

MYCL

256

P12524
ESLENPGAPHNPEPT

SSH2

1306

Q76I76
EPCNTQPCHLPQEVP

PAPLN

531

O95428
EIPQPDSGPRDSCQP

PLEKHG4B

731

Q96PX9
PCQPQEHAVSSPDPL

STAT6

746

P42226
AHEDCDEEPQFPPPS

SLC4A5

1091

Q9BY07
CQRHCPEPPSAPEEN

TBC1D30

841

Q9Y2I9
QPPVPRPEHCEGAAA

ZNRD2

116

O60232
RGCELPSNHQECPPP

ZNF469

3511

Q96JG9
VEHSPGPPPVDKQCQ

YY1AP1

721

Q9H869
VQPDPEPCAGQPSDS

ZNF133

636

P52736
CDPNPDDPLVPEIAH

UBE2D4

111

Q9Y2X8
LHPGNPCPEDQPQSQ

ZNF589

116

Q86UQ0
ASGQPHPTPEAPVEE

VSIG10L2

26

P0DP72
PEGQPSCAVHPSPEA

VSIG10L2

331

P0DP72
AECAGPPVPDPKNQH

TTC1

26

Q99614
GDACPPQHVPPKDSA

TBC1D10A

461

Q9BXI6
PEASGPEAEPCPELH

WDR91

356

A4D1P6
QAGPPETAHAADPQP

nan

56

Q8N6K4
PHLQPCNFGPEVVAP

PRO0461

46

Q9UI25
HASPDPPPELCSQGD

NACAD

146

O15069