Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	nuclear receptor binding	NR1H3 TACC2 ISL1 PAGR1 ZBTB7A TAF1 TAF11 TAF1L HR	1.43e-05	187	153	9	GO:0016922
GeneOntologyMolecularFunction	promoter-specific chromatin binding	ISL1 TRIM33 TAF1 TAF5 TAF1L NIPBL	4.26e-05	83	153	6	GO:1990841
GeneOntologyMolecularFunction	ubiquitin conjugating enzyme activity	UBE2O TAF1 TAF1L UBE2Z	1.80e-04	37	153	4	GO:0061631
GeneOntologyMolecularFunction	chromatin binding	TPR NR1H3 ISL1 MBD6 TRIM33 YBX2 TNRC18 SMARCD2 TAF1 TAF5 DMRT1 MBD2 TAF1L NIPBL CUX1 HR	1.80e-04	739	153	16	GO:0003682
GeneOntologyMolecularFunction	ubiquitin-like protein conjugating enzyme activity	UBE2O TAF1 TAF1L UBE2Z	3.24e-04	43	153	4	GO:0061650
GeneOntologyMolecularFunction	H3K27me3 modified histone binding	TAF1 TAF1L	5.75e-04	5	153	2	GO:0061628
GeneOntologyMolecularFunction	RNA polymerase II general transcription initiation factor activity	TAF1 TAF5 TAF11 TAF1L	6.74e-04	52	153	4	GO:0016251
HumanPheno	Spondylolysis	FLNA FLNB AGA	1.44e-05	6	47	3	HP:0003304
Domain	IG_FLMN	FLNA FLNB FLNC	5.73e-05	10	149	3	SM00557
Domain	TFIID_sub1_DUF3591	TAF1 TAF1L	6.32e-05	2	149	2	IPR022591
Domain	TBP-binding	TAF1 TAF1L	6.32e-05	2	149	2	PF09247
Domain	DUF3591	TAF1 TAF1L	6.32e-05	2	149	2	PF12157
Domain	TAF_II_230-bd	TAF1 TAF1L	6.32e-05	2	149	2	IPR009067
Domain	-	TAF1 TAF1L	6.32e-05	2	149	2	1.10.1100.10
Domain	TAF1_animal	TAF1 TAF1L	6.32e-05	2	149	2	IPR011177
Domain	Filamin	FLNA FLNB FLNC	7.83e-05	11	149	3	PF00630
Domain	FILAMIN_REPEAT	FLNA FLNB FLNC	7.83e-05	11	149	3	PS50194
Domain	Filamin/ABP280_rpt	FLNA FLNB FLNC	7.83e-05	11	149	3	IPR001298
Domain	Filamin/ABP280_repeat-like	FLNA FLNB FLNC	7.83e-05	11	149	3	IPR017868
Domain	CH	FLNA FLNB FLNC LRCH4 CNN2	1.70e-04	65	149	5	SM00033
Domain	CH	FLNA FLNB FLNC LRCH4 CNN2	2.41e-04	70	149	5	PF00307
Domain	-	FLNA FLNB FLNC LRCH4 CNN2	2.58e-04	71	149	5	1.10.418.10
Domain	CH	FLNA FLNB FLNC LRCH4 CNN2	2.93e-04	73	149	5	PS50021
Domain	CH-domain	FLNA FLNB FLNC LRCH4 CNN2	3.33e-04	75	149	5	IPR001715
Domain	GOLGA2L5	GOLGA6L2 GOLGA6L4 GOLGA8A	3.72e-04	18	149	3	PF15070
Domain	Golgin_A	GOLGA6L2 GOLGA6L4 GOLGA8A	3.72e-04	18	149	3	IPR024858
Domain	PH_dom-like	FRMPD4 ARHGAP23 RANBP3 ALS2 ARHGEF17 SH2B1 MTMR4 FGD5 PLCL1 MAPK8IP2 FAM43A	6.30e-04	426	149	11	IPR011993
Domain	ACTININ_2	FLNA FLNB FLNC	7.84e-04	23	149	3	PS00020
Domain	ACTININ_1	FLNA FLNB FLNC	7.84e-04	23	149	3	PS00019
Domain	Actinin_actin-bd_CS	FLNA FLNB FLNC	7.84e-04	23	149	3	IPR001589
Domain	GOLGA6L	GOLGA6L2 GOLGA6L4	9.29e-04	6	149	2	IPR026737
Domain	-	ARHGAP23 RANBP3 ALS2 ARHGEF17 SH2B1 MTMR4 FGD5 PLCL1 MAPK8IP2 FAM43A	1.19e-03	391	149	10	2.30.29.30
Domain	Transl_elong_EFTu/EF1A_C	GSPT1 GSPT2	1.72e-03	8	149	2	IPR004160
Domain	GTP_EFTU_D3	GSPT1 GSPT2	1.72e-03	8	149	2	PF03143
Domain	G_TR_CS	GSPT1 GSPT2	2.19e-03	9	149	2	IPR031157
Domain	Na_channel_asu	SCN4A SCN8A	2.73e-03	10	149	2	IPR001696
Domain	Na_trans_assoc	SCN4A SCN8A	2.73e-03	10	149	2	IPR010526
Domain	Na_trans_assoc	SCN4A SCN8A	2.73e-03	10	149	2	PF06512
Domain	Transl_elong_EF1A/Init_IF2_C	GSPT1 GSPT2	2.73e-03	10	149	2	IPR009001
Domain	BROMODOMAIN_1	TRIM33 TAF1 TAF1L	3.17e-03	37	149	3	PS00633
Domain	MBD	MBD6 MBD2	3.32e-03	11	149	2	SM00391
Domain	XK-related	XKR6 XKR4	3.32e-03	11	149	2	PF09815
Domain	MBD	MBD6 MBD2	3.32e-03	11	149	2	PS50982
Domain	Methyl_CpG_DNA-bd	MBD6 MBD2	3.32e-03	11	149	2	IPR001739
Domain	MBD	MBD6 MBD2	3.32e-03	11	149	2	PF01429
Domain	DNA-bd_dom	MBD6 MBD2	3.32e-03	11	149	2	IPR016177
Domain	XK_rel	XKR6 XKR4	3.32e-03	11	149	2	IPR018629
Domain	Bromodomain	TRIM33 TAF1 TAF1L	3.42e-03	38	149	3	PF00439
Domain	BROMODOMAIN_2	TRIM33 TAF1 TAF1L	4.25e-03	41	149	3	PS50014
Domain	Bromodomain	TRIM33 TAF1 TAF1L	4.55e-03	42	149	3	IPR001487
Domain	BROMO	TRIM33 TAF1 TAF1L	4.55e-03	42	149	3	SM00297
Domain	-	TRIM33 TAF1 TAF1L	4.55e-03	42	149	3	1.20.920.10
Domain	G_TR_1	GSPT1 GSPT2	4.65e-03	13	149	2	PS00301
Domain	Rho_GTPase_activation_prot	ARHGAP23 SH3BP1 ARHGAP30 PLXNB3	5.40e-03	88	149	4	IPR008936
Domain	uDENN	DENND2B MADD	5.40e-03	14	149	2	SM00800
Domain	PDZ	GIPC2 FRMPD4 ARHGAP23 SYNPO2L PDZD2	5.48e-03	141	149	5	PF00595
Domain	uDENN	DENND2B MADD	6.20e-03	15	149	2	PF03456
Domain	PDZ	GIPC2 FRMPD4 ARHGAP23 SYNPO2L PDZD2	6.71e-03	148	149	5	SM00228
Domain	DENN	DENND2B MADD	7.05e-03	16	149	2	SM00799
Domain	DENN	DENND2B MADD	7.05e-03	16	149	2	PF02141
Domain	dDENN	DENND2B MADD	7.05e-03	16	149	2	PF03455
Domain	UDENN	DENND2B MADD	7.05e-03	16	149	2	PS50946
Domain	DDENN	DENND2B MADD	7.05e-03	16	149	2	PS50947
Domain	dDENN	DENND2B MADD	7.05e-03	16	149	2	SM00801
Domain	dDENN_dom	DENND2B MADD	7.05e-03	16	149	2	IPR005112
Domain	uDENN_dom	DENND2B MADD	7.05e-03	16	149	2	IPR005113
Domain	DENN	DENND2B MADD	7.05e-03	16	149	2	PS50211
Domain	DENN_dom	DENND2B MADD	7.05e-03	16	149	2	IPR001194
Domain	-	GIPC2 FRMPD4 ARHGAP23 SYNPO2L PDZD2	7.09e-03	150	149	5	2.30.42.10
Domain	PDZ	GIPC2 FRMPD4 ARHGAP23 SYNPO2L PDZD2	7.29e-03	151	149	5	PS50106
Domain	PDZ	GIPC2 FRMPD4 ARHGAP23 SYNPO2L PDZD2	7.49e-03	152	149	5	IPR001478
Domain	AMP-bd_C	SLC27A5 SLC27A3	7.95e-03	17	149	2	IPR025110
Domain	AMP-binding_C	SLC27A5 SLC27A3	7.95e-03	17	149	2	PF13193
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	TPR CASC3 TRAF3IP1 CLASP1 ZBTB22 SH3BP1 WDR81 LMTK3 UBN2 KANK2 CCDC177 AKAP12 UBE2O PTPRN2 LZTS1 ZSCAN18 NAV1 PLCL1 TAF5 GOLGA8A PCDH8 NIPBL CEP170B CUX1 MAPK8IP2 LRRFIP1	2.91e-13	963	158	26	28671696
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	VWA5B2 USP34 FLNA FLNC SZT2 INTS1 AKNA LRRK1 ZFPM1 MBD6 MADD SCAF1 TNRC18 TMCC2 SCN8A NAV1 ZNRF1 SLC7A5 SH3BP5L C3orf18 RGL2 CEP170B ZNF687 HR	2.28e-10	1105	158	24	35748872
Pubmed	N-Terminomics for the Identification of In Vitro Substrates and Cleavage Site Specificity of the SARS-CoV-2 Main Protease.	TPR FLNA FLNB FLNC RANBP3 AKAP12 LIG3 GSPT2 NIPBL CNN2 ATPAF1 DYNC1I2 LRRFIP1	1.21e-08	360	158	13	33111431
Pubmed	Filamin A and Filamin B are co-expressed within neurons during periods of neuronal migration and can physically interact.	FLNA FLNB FLNC	9.20e-08	3	158	3	12393796
Pubmed	Genomic structure and fine mapping of the two human filamin gene paralogues FLNB and FLNC and comparative analysis of the filamin gene family.	FLNA FLNB FLNC	9.20e-08	3	158	3	11153914
Pubmed	Filamins as integrators of cell mechanics and signalling.	FLNA FLNB FLNC	9.20e-08	3	158	3	11252955
Pubmed	The SH2-containing inositol polyphosphate 5-phosphatase, SHIP-2, binds filamin and regulates submembraneous actin.	FLNA FLNB FLNC	3.67e-07	4	158	3	11739414
Pubmed	Structural interaction and functional regulation of polycystin-2 by filamin.	FLNA FLNB FLNC	3.67e-07	4	158	3	22802962
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	BICD2 FRMPD4 CLASP1 ALS2 ARHGEF17 MADD RHOBTB2 NAV1 SH3BP5L CEP170B PLXNB3 PDZD2	3.98e-07	407	158	12	12693553
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	BICD2 USP34 GAD2 FLNB NAGK TRAF3IP1 COPA CLIC6 KANK2 SH2B1 MADD TRIM33 UBE2O GLS FMN2 TAF1 NIPBL CUX1 PLXNB3 MAPK8IP2 LRRFIP1	4.14e-07	1285	158	21	35914814
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	CASC3 ZBTB16 CLASP1 RANBP3 ALS2 ARHGEF17 DENND2B MADD KIAA1671 MTMR4 CASKIN2 EIF4B NAV1 FMN2 SH3BP5L RGL2 CEP170B	4.45e-07	861	158	17	36931259
Pubmed	Proximity-dependent Mapping of the Androgen Receptor Identifies Kruppel-like Factor 4 as a Functional Partner.	RANBP3 PAGR1 UBN2 TRIM33 TNRC18 SMARCD2 TAF1 MBD2 NIPBL CUX1	4.59e-07	268	158	10	33640491
Pubmed	The TBN protein, which is essential for early embryonic mouse development, is an inducible TAFII implicated in adipogenesis.	TAF1 TAF5 TAF11 TAF1L	5.38e-07	15	158	4	14580349
Pubmed	Nephrocystin-conserved domains involved in targeting to epithelial cell-cell junctions, interaction with filamins, and establishing cell polarity.	FLNA FLNB FLNC	9.14e-07	5	158	3	12006559
Pubmed	Filamin B deficiency in mice results in skeletal malformations and impaired microvascular development.	FLNA FLNB FLNC	9.14e-07	5	158	3	17360453
Pubmed	HIV infection of T cells: actin-in and actin-out.	FLNA FLNB FLNC	9.14e-07	5	158	3	19366992
Pubmed	Neuron-specific protein network mapping of autism risk genes identifies shared biological mechanisms and disease-relevant pathologies.	BICD2 TPR FLNA GAD2 FLNB FRMPD4 TACC2 MADD TNRC18 UBE2O GSPT2 EIF4B TMCC2 GLS NAV1 SLC7A5 PCDH8 CEP170B LRRFIP1	1.14e-06	1139	158	19	36417873
Pubmed	The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.	DNAJB12 CASC3 PRSS8 GIPC2 CLASP1 INTS1 CMSS1 UBN2 KANK2 KIAA1671 TRIM33 SCAF1 ZBTB7A EIF4B LRCH4 SLC7A5 TAF5 MBD2 TAF1L NIPBL CEP170B ZNF687	1.26e-06	1497	158	22	31527615
Pubmed	Protein-protein interactions between large proteins: two-hybrid screening using a functionally classified library composed of long cDNAs.	FRMPD4 SH2B1 MADD PTPRN2 NAV1 PLXNB3 PDZD2	2.31e-06	130	158	7	12421765
Pubmed	Prediction of the coding sequences of mouse homologues of FLJ genes: the complete nucleotide sequences of 110 mouse FLJ-homologous cDnas identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	FLNA WDR81 ARHGAP30 LRCH4 SLC12A7 SLC27A3	2.60e-06	85	158	6	15449545
Pubmed	Large-scale characterization of HeLa cell nuclear phosphoproteins.	BICD2 TPR FLNA COPA CLASP1 PAGR1 ZFPM1 SCAF1 ZBTB7A EIF4B SLC7A5 NIPBL DYNC1I2 ZNF687 LRRFIP1	2.76e-06	774	158	15	15302935
Pubmed	The Z-disc proteins myotilin and FATZ-1 interact with each other and are connected to the sarcolemma via muscle-specific filamins.	FLNA FLNB FLNC	3.18e-06	7	158	3	16076904
Pubmed	Up-regulated expression of a novel gene in activated human peripheral blood mononuclear cells that is a truncated paralog of the human system L-amino acid transporter 1.	SLC7A5P2 SLC7A5 SLC7A5P1	3.18e-06	7	158	3	12009310
Pubmed	Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.	BICD2 TPR USP34 FLNA FLNB KIAA1671 GLS NAV1 TAF1 CUX1 ZNF687	3.67e-06	418	158	11	34709266
Pubmed	Specific interactions and potential functions of human TAFII100.	TAF1 TAF5 TAF11	5.07e-06	8	158	3	9045704
Pubmed	MEKK4 signaling regulates filamin expression and neuronal migration.	FLNA FLNB FLNC	5.07e-06	8	158	3	17145501
Pubmed	Interaction network of human early embryonic transcription factors.	PAGR1 MBD6 UBN2 KIAA1671 TRIM33 LIG3 TNRC18 SMARCD2 TAF1 NIPBL	5.15e-06	351	158	10	38297188
Pubmed	The SOX2-interactome in brain cancer cells identifies the requirement of MSI2 and USP9X for the growth of brain tumor cells.	USP34 IRF2BP1 INTS1 TRIM33 ZBTB7A TNRC18 MBD2 CUX1 ZNF687	6.24e-06	282	158	9	23667531
Pubmed	An antibody-based proximity labeling map reveals mechanisms of SARS-CoV-2 inhibition of antiviral immunity.	DNAJB12 USP34 CASC3 CLASP1 KANK2 MADD UBE2O MTMR4 PGRMC2 LRCH4 NAV1 SLC7A5 SH3BP5L ZNF687	7.09e-06	733	158	14	34672954
Pubmed	Assembly of the U5 snRNP component PRPF8 is controlled by the HSP90/R2TP chaperones.	DNAJB12 TPR FLNA FLNB COPA CLASP1 TACC2 CMSS1 GSPT1 UBE2O TRIR GSPT2 EIF4B NAV1 SLC7A5 DCTPP1 NIPBL CNN2 DYNC1I2 LRRFIP1	7.11e-06	1415	158	20	28515276
Pubmed	Different splice variants of filamin-B affect myogenesis, subcellular distribution, and determine binding to integrin [beta] subunits.	FLNA FLNB FLNC	7.57e-06	9	158	3	11807098
Pubmed	Human transcription factor protein interaction networks.	FOXQ1 IRF2BP1 COPA PAGR1 MBD6 UBN2 KIAA1671 TRIM33 LIG3 ZBTB7A UBE2O ZSCAN18 SMARCD2 TAF1 TAF5 MBD2 TAF1L NIPBL CUX1 ZNF687	8.21e-06	1429	158	20	35140242
Pubmed	Filamin-interacting proteins, Cfm1 and Cfm2, are essential for the formation of cartilaginous skeletal elements.	FLNA FLNB ACAN	1.08e-05	10	158	3	24436304
Pubmed	EWS, but not EWS-FLI-1, is associated with both TFIID and RNA polymerase II: interactions between two members of the TET family, EWS and hTAFII68, and subunits of TFIID and RNA polymerase II complexes.	TAF1 TAF5 TAF11	1.08e-05	10	158	3	9488465
Pubmed	E-cadherin interactome complexity and robustness resolved by quantitative proteomics.	FLNA FLNB ARHGAP23 VASN KANK2 GSPT1 KIAA1671 CASKIN2 EIF4B PGRMC2 CNN2 LRRFIP1	1.16e-05	565	158	12	25468996
Pubmed	Comparative proximity biotinylation implicates the small GTPase RAB18 in sterol mobilization and biosynthesis.	BICD2 TPR FLNA FLNB FLNC RANBP3 AKAP12 PGRMC2 SLC7A5 SLC12A7 CNN2 CUX1	1.22e-05	568	158	12	37774976
Pubmed	Mouse endothelial OTUD1 promotes angiotensin II-induced vascular remodeling by deubiquitinating SMAD3.	FLNA FLNB FLNC	1.48e-05	11	158	3	36579465
Pubmed	CCAAT binding NF-Y-TBP interactions: NF-YB and NF-YC require short domains adjacent to their histone fold motifs for association with TBP basic residues.	TAF1 TAF5 TAF11	1.48e-05	11	158	3	9153318
Pubmed	Host PDZ-containing proteins targeted by SARS-CoV-2.	GIPC2 FRMPD4 SYNPO2L PDZD2	1.92e-05	35	158	4	33864728
Pubmed	Involvement of human release factors eRF3a and eRF3b in translation termination and regulation of the termination complex formation.	GSPT1 GSPT2	2.05e-05	2	158	2	15987998
Pubmed	Disruption of the Flnb gene in mice phenocopies the human disease spondylocarpotarsal synostosis syndrome.	FLNA FLNB	2.05e-05	2	158	2	17635842
Pubmed	A novel human actin-binding protein homologue that binds to platelet glycoprotein Ibalpha.	FLNB FLNC	2.05e-05	2	158	2	9694715
Pubmed	Taf1 knockout is lethal in embryonic male mice and heterozygous females show weight and movement disorders.	TAF1 TAF1L	2.05e-05	2	158	2	38804708
Pubmed	Mapping of two genes encoding isoforms of the actin binding protein ABP-280, a dystrophin like protein, to Xq28 and to chromosome 7.	FLNA FLNC	2.05e-05	2	158	2	7689010
Pubmed	Sustained expression of a neuron-specific isoform of the Taf1 gene in development stages and aging in mice.	TAF1 TAF1L	2.05e-05	2	158	2	22842574
Pubmed	Frameshift Mutations in the Mononucleotide Repeats of TAF1 and TAF1L Genes in Gastric and Colorectal Cancers with Regional Heterogeneity.	TAF1 TAF1L	2.05e-05	2	158	2	27571988
Pubmed	Striatal Cholinergic Dysregulation after Neonatal Decrease in X-Linked Dystonia Parkinsonism-Related TAF1 Isoforms.	TAF1 TAF1L	2.05e-05	2	158	2	34403156
Pubmed	Filamin depletion blocks endoplasmic spreading and destabilizes force-bearing adhesions.	FLNA FLNB	2.05e-05	2	158	2	21325628
Pubmed	Interaction between DMRT1 and PLZF protein regulates self-renewal and proliferation in male germline stem cells.	ZBTB16 DMRT1	2.05e-05	2	158	2	33200378
Pubmed	Filamin isogene expression during mouse myogenesis.	FLNA FLNC	2.05e-05	2	158	2	10679933
Pubmed	A novel structural unit in the N-terminal region of filamins.	FLNA FLNC	2.05e-05	2	158	2	24469451
Pubmed	The limits of promiscuity: isoform-specific dimerization of filamins.	FLNB FLNC	2.05e-05	2	158	2	12525170
Pubmed	Structural and functional aspects of filamins.	FLNA FLNB	2.05e-05	2	158	2	11336782
Pubmed	The variants at FLNA and FLNB contribute to the susceptibility of hypertension and stroke with differentially expressed mRNA.	FLNA FLNB	2.05e-05	2	158	2	33649519
Pubmed	Adapter protein SH2B1beta binds filamin A to regulate prolactin-dependent cytoskeletal reorganization and cell motility.	FLNA SH2B1	2.05e-05	2	158	2	21566085
Pubmed	TAFII250, Egr-1, and D-type cyclin expression in mice and neonatal rat cardiomyocytes treated with doxorubicin.	TAF1 TAF1L	2.05e-05	2	158	2	10070062
Pubmed	The Promyelocytic Leukemia Zinc Finger (PLZF ) gene is a novel transcriptional target of the CCAAT-Displacement-protein (CUX1) repressor.	ZBTB16 CUX1	2.05e-05	2	158	2	20945532
Pubmed	Functional role of Tia1/Pub1 and Sup35 prion domains: directing protein synthesis machinery to the tubulin cytoskeleton.	GSPT1 GSPT2	2.05e-05	2	158	2	24981173
Pubmed	The in vivo Interaction Landscape of Histones H3.1 and H3.3.	MIER2 CENPT INTS1 UBN2 LIG3 UBE2O TRIR ZSCAN18 SMARCD2 TAF1 NIPBL CUX1	2.38e-05	608	158	12	36089195
Pubmed	The PHLPP1 N-Terminal Extension Is a Mitotic Cdk1 Substrate and Controls an Interactome Switch.	TPR FLNA FLNB RANBP3 KANK2 EIF4B SLC7A5 CNN2	2.40e-05	256	158	8	33397691
Pubmed	Transcription factor TFIID recruits factor CPSF for formation of 3' end of mRNA.	TAF1 TAF5 TAF11	2.54e-05	13	158	3	9311784
Pubmed	A Degradation Motif in STAU1 Defines a Novel Family of Proteins Involved in Inflammation.	BICD2 FLNA FLNC COPA UBN2 AKAP12 GSPT1 TRIR EIF4B SMARCD2 CNN2 DYNC1I2 LRRFIP1	2.89e-05	724	158	13	36232890
Pubmed	Structure of promoter-bound TFIID and model of human pre-initiation complex assembly.	TAF1 TAF5 TAF11	3.23e-05	14	158	3	27007846
Pubmed	Identification of a small TAF complex and its role in the assembly of TAF-containing complexes.	TAF1 TAF5 TAF11	3.23e-05	14	158	3	17375202
Pubmed	Human TFIID binds to core promoter DNA in a reorganized structural state.	TAF1 TAF5 TAF11	3.23e-05	14	158	3	23332750
Pubmed	TNF-α inhibits glucocorticoid receptor-induced gene expression by reshaping the GR nuclear cofactor profile.	IRF2BP1 GOLGA6L2 CMSS1 LIG3 PTPRN2 LZTS1 GLS FGD5 DNAAF1 NIPBL CUX1 ZNF687	3.79e-05	638	158	12	31182584
Pubmed	Dominant and redundant functions of TFIID involved in the regulation of hepatic genes.	TAF1 TAF5 TAF11 TAF1L	4.41e-05	43	158	4	18722179
Pubmed	SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.	TPR FLNA RANBP3 UBN2 KIAA1671 UBE2O PGRMC2 TAF1 TAF5 CUX1 LRRFIP1	4.58e-05	549	158	11	38280479
Pubmed	Mutations in the carboxy-terminal domain of TBP affect the synthesis of human immunodeficiency virus type 1 full-length and short transcripts similarly.	TAF1 TAF5 TAF11	4.93e-05	16	158	3	8764009
Pubmed	Differential expression of the Tmem132 family genes in the developing mouse nervous system.	ISL1 EN2 CUX1	4.93e-05	16	158	3	35690356
Pubmed	Wild-type and transactivation-defective mutants of human immunodeficiency virus type 1 Tat protein bind human TATA-binding protein in vitro.	TAF1 TAF5 TAF11	4.93e-05	16	158	3	8680883
Pubmed	A novel LBP-1-mediated restriction of HIV-1 transcription at the level of elongation in vitro.	TAF1 TAF5 TAF11	4.93e-05	16	158	3	7836461
Pubmed	Novel mechanism and factor for regulation by HIV-1 Tat.	TAF1 TAF5 TAF11	4.93e-05	16	158	3	7835343
Pubmed	Filamin A- and formin 2-dependent endocytosis regulates proliferation via the canonical Wnt pathway.	FLNA FLNB FMN2	4.93e-05	16	158	3	27789627
Pubmed	Direct interaction of human TFIID with the HIV-1 transactivator tat.	TAF1 TAF5 TAF11	4.93e-05	16	158	3	8121496
Pubmed	Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.	USP34 ARHGAP23 KANK2 KIAA1671 TRIM33 SCAF1 ZBTB7A IL21R FMN2 SMARCD2 TAF1 TAF5 TAF11 MBD2 CEP170B ZNF687	5.26e-05	1116	158	16	31753913
Pubmed	Integrated Proteomics-Based Physical and Functional Mapping of AXL Kinase Signaling Pathways and Inhibitors Define Its Role in Cell Migration.	FLNA KANK2 AKAP12 PGRMC2	5.77e-05	46	158	4	35022314
Pubmed	Opposing FlnA and FlnB interactions regulate RhoA activation in guiding dynamic actin stress fiber formation and cell spreading.	FLNA FLNB	6.13e-05	3	158	2	28175289
Pubmed	Altered mucosal DNA methylation in parallel with highly active Helicobacter pylori-related gastritis.	FLNC THBD	6.13e-05	3	158	2	23292007
Pubmed	Indications for a novel muscular dystrophy pathway. gamma-filamin, the muscle-specific filamin isoform, interacts with myotilin.	FLNA FLNC	6.13e-05	3	158	2	11038172
Pubmed	The regulatory repertoire of PLZF and SALL4 in undifferentiated spermatogonia.	ZBTB16 DMRT1	6.13e-05	3	158	2	27068105
Pubmed	Prominent role of forebrain excitatory neurons in SCN8A encephalopathy.	GAD2 SCN8A	6.13e-05	3	158	2	30601941
Pubmed	Polypeptide chain release factor eRF3 is a novel molecular partner of survivin.	GSPT1 GSPT2	6.13e-05	3	158	2	23377885
Pubmed	An acetylation switch in p53 mediates holo-TFIID recruitment.	TAF1 TAF5	6.13e-05	3	158	2	17996705
Pubmed	Localization and enhanced current density of the Kv4.2 potassium channel by interaction with the actin-binding protein filamin.	FLNA FLNC	6.13e-05	3	158	2	11102480
Pubmed	Filamin A negatively regulates the transcriptional activity of p73alpha in the cytoplasm.	FLNA FLNC	6.13e-05	3	158	2	17825253
Pubmed	Multiple microRNAs within the 14q32 cluster target the mRNAs of major type 1 diabetes autoantigens IA-2, IA-2β, and GAD65.	GAD2 PTPRN2	6.13e-05	3	158	2	26148972
Pubmed	Cytoskeletal protein ABP-280 directs the intracellular trafficking of furin and modulates proprotein processing in the endocytic pathway.	FLNA FLNC	6.13e-05	3	158	2	9412467
Pubmed	The F-actin cross-linking and focal adhesion protein filamin A is a ligand and in vivo substrate for protein kinase C alpha.	FLNA FLNC	6.13e-05	3	158	2	12704190
Pubmed	Molecular cloning of a novel member of the eukaryotic polypeptide chain-releasing factors (eRF). Its identification as eRF3 interacting with eRF1.	GSPT1 GSPT2	6.13e-05	3	158	2	9712840
Pubmed	Regulated expression of TAF1 in 1-cell mouse embryos.	TAF1 TAF1L	6.13e-05	3	158	2	16822332
Pubmed	Cut-like homeobox 1 and nuclear factor I/B mediate ENGRAILED2 autism spectrum disorder-associated haplotype function.	EN2 CUX1	6.13e-05	3	158	2	22180456
Pubmed	Decreased A-to-I RNA editing as a source of keratinocytes' dsRNA in psoriasis.	FLNA COPA	6.13e-05	3	158	2	29592874
Pubmed	GPIbα regulates platelet size by controlling the subcellular localization of filamin.	FLNA FLNB	6.13e-05	3	158	2	22174152
Pubmed	TAFII55 binding to TAFII250 inhibits its acetyltransferase activity.	TAF1 TAF1L	6.13e-05	3	158	2	11592977
Pubmed	Functional substitution for TAF(II)250 by a retroposed homolog that is expressed in human spermatogenesis.	TAF1 TAF1L	6.13e-05	3	158	2	12217962
Pubmed	TAF7: a possible transcription initiation check-point regulator.	TAF1 TAF1L	6.13e-05	3	158	2	16407123
Pubmed	The processed isoform of the translation termination factor eRF3 localizes to the nucleus to interact with the ARF tumor suppressor.	GSPT1 GSPT2	6.13e-05	3	158	2	24569073
Pubmed	Sustained generation of neurons destined for neocortex with oxidative metabolic upregulation upon filamin abrogation.	FLNA FLNB	6.13e-05	3	158	2	38989458
Pubmed	BioID Performed on Golgi Enriched Fractions Identify C10orf76 as a GBF1 Binding Protein Essential for Golgi Maintenance and Secretion.	TPR FLNB RANBP3 KANK2 GSPT1 EIF4B CNN2	6.24e-05	216	158	7	31519766
Interaction	RAPGEF5 interactions	FLNC ARHGAP23 ARHGAP30 ARHGEF17 SLC7A5 MAPK8IP2	6.68e-06	60	155	6	int:RAPGEF5
GeneFamily	Sodium voltage-gated channel alpha subunits	SCN4A SCN8A	8.82e-04	9	91	2	1203
GeneFamily	PDZ domain containing	GIPC2 FRMPD4 ARHGAP23 SYNPO2L PDZD2	1.02e-03	152	91	5	1220
GeneFamily	Blood group antigens\|XK related family	XKR6 XKR4	1.34e-03	11	91	2	955
GeneFamily	Zinc fingers CXXC-type\|Methyl-CpG binding domain containing	MBD6 MBD2	1.34e-03	11	91	2	1025
GeneFamily	Rho GTPase activating proteins\|BCH domain containing	ARHGAP23 SH3BP1 ARHGAP30	2.04e-03	50	91	3	721
Coexpression	MARTENS_BOUND_BY_PML_RARA_FUSION	DNAJB12 TPR FLNB ZBTB16 WDR81 AKNA ARHGAP30 MBD6 UBN2 SH2B1 UBE2O TMCC2 SLC7A5 SLC7A5P1 CUX1	1.22e-07	456	158	15	M2094
Coexpression	LIU_PROSTATE_CANCER_DN	FLNA FLNC FOXQ1 ARHGAP23 MRGPRF CLIC6 KANK2 DENND2B AKAP12 MSRB3 FCGBP PNMA8A FGD5 LTBP1 PLCL1	3.32e-07	493	158	15	M19391
Coexpression	IVANOVA_HEMATOPOIESIS_STEM_CELL_AND_PROGENITOR	MIER2 FLNB PRSS8 ARHGEF17 KANK2 SH2B1 KIAA1671 PTPRCAP SCN8A NAV1 FGD5 SLC12A7 EN2 CEP170B FAM43A	2.20e-06	574	158	15	M8215
Coexpression	IVANOVA_HEMATOPOIESIS_STEM_CELL_AND_PROGENITOR	MIER2 FLNB PRSS8 ARHGEF17 KANK2 SH2B1 KIAA1671 PTPRCAP SCN8A NAV1 FGD5 SLC12A7 EN2 CEP170B FAM43A	3.78e-06	600	158	15	MM1025
Coexpression	BENPORATH_ES_WITH_H3K27ME3	GAD2 TRADD ZBTB16 FOXQ1 FRMPD4 ISL1 ZFPM1 ZBTB7A THBD KCNC4 PTPRN2 ACAN SLC35D3 GCC1 DMRT1 EN2 PCDH8 MAPK8IP2 PDZD2 HR	1.33e-05	1115	158	20	M10371
Coexpression	GSE34205_HEALTHY_VS_RSV_INF_INFANT_PBMC_UP	FBXL17 ARHGAP30 AKAP12 KIAA1671 TRIR EIF4B UBE2Z FAM43A	2.43e-05	194	158	8	M5136
Coexpression	GSE27786_NKTCELL_VS_MONO_MAC_UP	INTS1 AKNA ARHGAP30 CMSS1 UBN2 ZBTB7A AGA ATPAF1	3.03e-05	200	158	8	M4870
Coexpression	GSE34006_UNTREATED_VS_A2AR_AGONIST_TREATED_TREG_DN	DDAH2 NAGK AKNA TNRC18 PTPRCAP EIF4B IL21R SMARCD2	3.03e-05	200	158	8	M9050
Coexpression	GSE6875_WT_VS_FOXP3_KO_TREG_UP	FLNA INTS1 ZBTB22 AKAP12 TRIR SHF MBD2 CNN2	3.03e-05	200	158	8	M6803
ToppCell	Hippocampus-Neuronal\|Hippocampus / BrainAtlas - Mouse McCarroll V32	USP34 SH3BP1 LMTK3 XKR4 MADD UBE2O PTPRN2 GLS SCN8A CEP170B	2.02e-09	194	158	10	8aeb347b3024354c9505f4f0fddf0b843489dc6b
ToppCell	5'-Adult-Distal_Rectal-Mesenchymal-Pericytes\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	FLNA MRGPRF ARHGEF17 KANK2 MSRB3 ACAN RBPMS2 LTBP1 PCDH8	3.16e-08	193	158	9	7631bf3362b4fa061ffeab4879ab12c4708dc4c0
ToppCell	5'-Adult-Distal_Rectal-Mesenchymal-Pericytes-Contractile_pericyte_(PLN+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	FLNA MRGPRF ARHGEF17 KANK2 MSRB3 ACAN RBPMS2 LTBP1 PCDH8	3.16e-08	193	158	9	8d15c63f2ae48d0a00d7ef5fdafa917ab8ad0571
ToppCell	3'-Distal_airway-Mesenchymal-Mesenchymal_Myocytic-tracheobronchial_smooth_muscle_cell\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	FLNA ZBTB16 VASN MRGPRF KANK2 AKAP12 MSRB3 LZTS1 LTBP1	3.60e-08	196	158	9	f78951b460913866d092ba92af70ea76a2afa73e
ToppCell	3'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-tracheobronchial_smooth_muscle_cell-SM_activated_stress_response-SM_activated_stress_response_L.2.3.0.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	FLNA FLNC VASN MRGPRF KANK2 AKAP12 MSRB3 RBPMS2 LTBP1	3.60e-08	196	158	9	ac4c8571bd792538f8df7b9bdd90ef58405fd3b1
ToppCell	3'-Distal_airway-Mesenchymal-Mesenchymal_Myocytic-tracheobronchial_smooth_muscle_cell-Smooth_muscle\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	FLNA ZBTB16 VASN MRGPRF KANK2 AKAP12 MSRB3 LZTS1 LTBP1	3.60e-08	196	158	9	69ad90a429af4dad5a45556544224001ebcb1607
ToppCell	3'-Distal_airway-Mesenchymal-Mesenchymal_Myocytic-tracheobronchial_smooth_muscle_cell-Smooth_muscle-Smooth_muscle_L.2.3.0.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	FLNA ZBTB16 VASN MRGPRF KANK2 AKAP12 MSRB3 LZTS1 LTBP1	3.60e-08	196	158	9	4da96672a9c72268cfcc82d61eb3caae6e02d4c4
ToppCell	3'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-tracheobronchial_smooth_muscle_cell-SM_activated_stress_response\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	FLNA FLNC VASN MRGPRF KANK2 AKAP12 MSRB3 RBPMS2 LTBP1	3.60e-08	196	158	9	70b2e0b4ff4f1bc03fb72ace07a8a44f4b415922
ToppCell	Parenchymal-10x5prime-Stromal-Myofibroblastic\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	VASN MRGPRF ARHGEF17 KANK2 AKAP12 MSRB3 LZTS1 ACAN LTBP1	4.11e-08	199	158	9	20f760d92c351a1dac4cc0a424c443ea03a179fe
ToppCell	LPS_anti-TNF-Mesenchymal_myocytic-Pericyte-Pericyte_3\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	FLNA VASN MRGPRF TACC2 ARHGEF17 KANK2 ACAN RBPMS2 LTBP1	4.29e-08	200	158	9	9169a9ec8e9ab95d90a64c5a19ac666a5cf82313
ToppCell	LPS_IL1RA-Mesenchymal_myocytic-Pericyte-Pericyte_3\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	FLNA MRGPRF TACC2 ARHGEF17 KANK2 ACAN RBPMS2 LTBP1 PLCL1	4.29e-08	200	158	9	a3a1e35934d676c39f917652e50c502cb2f613c1
ToppCell	LPS_only-Mesenchymal_myocytic-Pericyte-Pericyte_3\|LPS_only / Treatment groups by lineage, cell group, cell type	FLNA VASN MRGPRF TACC2 ARHGEF17 KANK2 ACAN RBPMS2 LTBP1	4.29e-08	200	158	9	7c62678cf408aaaf98d6df0fb27814d2007c4521
ToppCell	droplet-Thymus-nan-24m-Lymphocytic-Double_negative_Thymocyte,_DN4_(Cd8-,_Cd4-),_some_undergoing_VDJ_recombination_\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ZBTB16 XKR6 LMTK3 ARHGEF17 KIAA1671 THBD RBPMS2 SLC27A3	2.49e-07	178	158	8	408e41c853f608965cef9111fb87fdc311cdc7a8
ToppCell	facs-Large_Intestine-Proximal-18m-Epithelial-enteroendocrine_cell\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	VWA5B2 ISL1 PTPRN2 SLC35D3 ZSCAN18 NAV1 SAMD14 MAPK8IP2	2.71e-07	180	158	8	9db9899ca42455310e9b63df523fe6c4780abfb7
ToppCell	Pericytes-Cryobiopsy_01\|World / lung cells shred on cell class, cell subclass, sample id	FLNC MRGPRF KANK2 MSRB3 KCNC4 ACAN RBPMS2 LTBP1	2.95e-07	182	158	8	46c213597445b1f4f09dc367f27702d24b201daf
ToppCell	Endothelial-B-Donor_07\|World / lung cells shred on cell class, cell subclass, sample id	FLNB FLNC ARHGAP23 AKAP12 MSRB3 THBD SLC7A5 FAM43A	3.34e-07	185	158	8	133c9dc64d564dae4aeeeca22f386aa3f13fa980
ToppCell	LPS-antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_3\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	MRGPRF STYXL2 KANK2 MSRB3 ACAN RBPMS2 LTBP1 PLCL1	3.48e-07	186	158	8	4780af76237d7af2abbe2d8d5530cdf53e3ed0b7
ToppCell	5'-Adult-SmallIntestine-Mesenchymal-myocytic\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	FLNA FLNC MRGPRF KANK2 AKAP12 MSRB3 FMN2 LTBP1	3.93e-07	189	158	8	ab7ece0a517499b70b7754720d3e434765363af6
ToppCell	LPS-IL1RA-Endothelial-Endothelial-Artery\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	FLNB GIPC2 LRRK1 KIAA1671 SCN4A NAV1 FGD5 LTBP1	4.09e-07	190	158	8	aed65d584ca0c25f6a8313c66b421a6618af82ea
ToppCell	LPS-antiTNF-Endothelial-Endothelial-Artery\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	FLNB GIPC2 LRRK1 KIAA1671 SCN4A NAV1 FGD5 LTBP1	4.26e-07	191	158	8	4b3d5157344dbfbf4fab518611cd9fa37fac7bd9
ToppCell	Pericytes\|World / lung cells shred on cell class, cell subclass, sample id	FLNC MRGPRF KANK2 AKAP12 MSRB3 ACAN RBPMS2 LTBP1	4.43e-07	192	158	8	057ad22b878c0c5fb59ed1412ca13db945c57a5a
ToppCell	5'-GW_trimst-2-LargeIntestine-Mesenchymal-myocytic\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	FLNA FLNC MRGPRF KANK2 DENND2B AKAP12 MSRB3 RBPMS2	4.43e-07	192	158	8	d0fb6885f023d55a2b7984c99db9c6463258f788
ToppCell	5'-GW_trimst-2-SmallIntestine-Mesenchymal-myocytic-SMC_(PLPP2+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	FLNA FLNC MRGPRF KANK2 AKAP12 MSRB3 RBPMS2 LTBP1	4.61e-07	193	158	8	173f1d83133f5ffa88e2a75d28835ad7acd2aa90
ToppCell	facs-Brain_Non-Myeloid-Cortex-3m-Mesenchymal-Pericyte\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FLNA VASN MRGPRF CMSS1 ARHGEF17 KANK2 RBPMS2 LTBP1	4.79e-07	194	158	8	bf34737ae2dc218f890fbb9201c308b324415749
ToppCell	facs-Brain_Non-Myeloid-Cortex-3m-Mesenchymal\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FLNA VASN MRGPRF CMSS1 ARHGEF17 KANK2 RBPMS2 LTBP1	4.79e-07	194	158	8	b35e33439b6d3b5d69147e617224d2c8fd056223
ToppCell	facs-Brain_Non-Myeloid-Cortex-3m-Mesenchymal-brain_pericyte\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FLNA VASN MRGPRF CMSS1 ARHGEF17 KANK2 RBPMS2 LTBP1	4.79e-07	194	158	8	4ebed7a6731b88c8359860072cbeba355a7e90ac
ToppCell	facs-Brain_Non-Myeloid-Cerebellum-3m-Mesenchymal-Pericyte\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FLNA VASN MRGPRF ARHGEF17 DENND2B KIAA1671 RBPMS2 LTBP1	5.18e-07	196	158	8	184104cbea0461dd2757668ab9755948ac7b585a
ToppCell	facs-Brain_Non-Myeloid-Cerebellum-3m-Mesenchymal\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FLNA VASN MRGPRF ARHGEF17 DENND2B KIAA1671 RBPMS2 LTBP1	5.18e-07	196	158	8	bebb20dc210576101c317011e3afb59798f5d255
ToppCell	facs-Brain_Non-Myeloid-Cerebellum-3m-Mesenchymal-brain_pericyte\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FLNA VASN MRGPRF ARHGEF17 DENND2B KIAA1671 RBPMS2 LTBP1	5.18e-07	196	158	8	8114e98923096c54b6834f21550c3061bab6773d
ToppCell	kidney_cells-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	FLNA ARHGEF17 KANK2 MSRB3 LZTS1 ACAN RBPMS2 LTBP1	5.38e-07	197	158	8	8b3bf5b45e49bf1c60e4d2703b470bb890385f67
ToppCell	kidney_cells-Adult_normal_reference-Mesenchymal\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	FLNA ARHGEF17 KANK2 MSRB3 LZTS1 ACAN RBPMS2 LTBP1	5.38e-07	197	158	8	02e70768a917c5f097bc653e9e965a1000289d2e
ToppCell	Bronchial-10x5prime-Stromal-Myofibroblastic-Muscle_smooth_pulmonary\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	FLNC MRGPRF ARHGEF17 KANK2 AKAP12 MSRB3 LZTS1 ACAN	5.59e-07	198	158	8	705118a5db366b43ffd3389c60e4cb392ad3f2e6
ToppCell	cellseq-Mesenchymal-Myocytic-Myocytic_2-VSMC\|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	FLNA FLNC VASN MRGPRF KANK2 MSRB3 RBPMS2 LTBP1	5.59e-07	198	158	8	e967c601101361fc1c48dab0e5b76dc68813276e
ToppCell	Parenchymal-10x5prime-Stromal-Myofibroblastic-Muscle_smooth_pulmonary\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	MRGPRF ARHGEF17 KANK2 AKAP12 MSRB3 LZTS1 ACAN LTBP1	5.81e-07	199	158	8	7c272a1aa7f3e931ad5d20809719d85b3bce4cb0
ToppCell	Tracheal-10x5prime-Stromal-Myofibroblastic-Muscle_smooth_systemic_arterial\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	FLNA ARHGEF17 AKAP12 MSRB3 ACAN RBPMS2 ALPK3 LTBP1	5.81e-07	199	158	8	c2903b1a4b91e94bbdaa909bacefe901255cf248
ToppCell	LPS_IL1RA_TNF-Mesenchymal_myocytic-Pericyte\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	FLNA VASN MRGPRF ARHGEF17 KANK2 LZTS1 ACAN PLCL1	6.03e-07	200	158	8	b5b5a32925f225610fe25a021a742d6397162863
ToppCell	distal-3-mesenchymal-Airway_Smooth_Muscle\|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	FLNC VASN MRGPRF KANK2 MSRB3 KCNC4 RBPMS2 LTBP1	6.03e-07	200	158	8	4072cfb3047954f507289587b4bfaf1526936992
ToppCell	kidney_cells-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell-\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	FLNA FLNC ARHGEF17 KANK2 MSRB3 ACAN LTBP1	2.88e-06	173	158	7	fc2602b2ce051cd4c33957d7e3d041ff8a529883
ToppCell	kidney_cells-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	FLNA FLNC ARHGEF17 KANK2 MSRB3 ACAN LTBP1	2.88e-06	173	158	7	901b8e6909c1f3849906fad9cee17b8f0bab050d
ToppCell	Fetal_29-31_weeks-Mesenchymal-airway_smooth_muscle_cell-D150\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	FLNA MRGPRF TACC2 KANK2 MSRB3 IL21R LTBP1	3.88e-06	181	158	7	25915e2500430a902db37d79a749ce2990b69810
ToppCell	Fetal_29-31_weeks-Mesenchymal-myofibroblast_cell-D062\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	FLNA KANK2 DENND2B MSRB3 THBD LTBP1 HR	3.88e-06	181	158	7	d7e04e0ca549eac6d9b1192b6578f9b54943d54f
ToppCell	3'-Pediatric_IBD-SmallIntestine-Mesenchymal-myocytic-myofibroblast_(RSPO2+)\|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract	FLNA FLNC MRGPRF KANK2 MSRB3 FMN2 LTBP1	3.88e-06	181	158	7	ab0f300d14b62cef57f1b0bdae143b8dfe8e6975
ToppCell	3'-Child09-12-SmallIntestine-Mesenchymal-myocytic-myofibroblast\|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	FLNA MRGPRF KANK2 DENND2B AKAP12 NAV1 LTBP1	4.17e-06	183	158	7	6b5eef96b28911c752a8b6c0975918c4572cec38
ToppCell	Fetal_29-31_weeks-Endothelial-endothelial_cell_of_lymph_vessel-D088\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	FLNB FLNC ARHGAP23 AKAP12 KIAA1671 THBD FGD5	4.17e-06	183	158	7	bc98df870de65aff6dab295c24cbc199c7f2aa15
ToppCell	facs-Brain_Non-Myeloid-Striatum-3m-Mesenchymal-brain_pericyte\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FLNA VASN MRGPRF SYNPO2L KANK2 RBPMS2 LTBP1	4.32e-06	184	158	7	89ae8bf1a6c2d355d279d23a5e24a08d9ec2334e
ToppCell	facs-Large_Intestine-Distal-3m-Epithelial-enteroendocrine_cell\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	VWA5B2 ISL1 XKR6 KCNC4 PNMA8A FMN2 MAPK8IP2	4.32e-06	184	158	7	3da93e7d8b62463e307cc0425c47dbd3bef66799
ToppCell	5'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-tracheobronchial_smooth_muscle_cell-Fibromyocytes\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	FLNC MRGPRF SYNPO2L MSRB3 ACAN RBPMS2 LTBP1	4.32e-06	184	158	7	54e5b63f55b8d6eccad53d389ea9c78f991e1414
ToppCell	facs-Brain_Non-Myeloid-Striatum-3m-Mesenchymal-Pericyte\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FLNA VASN MRGPRF SYNPO2L KANK2 RBPMS2 LTBP1	4.32e-06	184	158	7	34c84ac9a32eaf96f45b79485119cad65905817d
ToppCell	Pericytes-Donor_07\|World / lung cells shred on cell class, cell subclass, sample id	FLNC VASN AKAP12 MSRB3 LZTS1 ACAN LTBP1	4.32e-06	184	158	7	3d2d55d0f22874be21665ab37da710482f77fc36
ToppCell	5'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-tracheobronchial_smooth_muscle_cell-Fibromyocytes-Fibromyocytes_L.2.3.2.1\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	FLNC MRGPRF SYNPO2L MSRB3 ACAN RBPMS2 LTBP1	4.32e-06	184	158	7	7b5678718719020b52e7c2a7bd9797987defd7ff
ToppCell	Fetal_29-31_weeks-Epithelial-lung_neuroendocrine_cell_(PNEC)\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	VWA5B2 PTPRN2 SLC35D3 SCN8A FMN2 MARCHF11 MAPK8IP2	4.64e-06	186	158	7	b45cce768e4bf91da194fd9660cab7520dfb15ac
ToppCell	5'-GW_trimst-2-LargeIntestine-Mesenchymal-myocytic-SMC_(PLPP2+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	FLNA FLNC MRGPRF AKAP12 MSRB3 RBPMS2 LTBP1	4.81e-06	187	158	7	3912bbb610a4a84791e9bda92a2d57a52c31d29e
ToppCell	Fetal_29-31_weeks-Epithelial-lung_neuroendocrine_cell_(PNEC)-D150\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	VWA5B2 PTPRN2 SLC35D3 SCN8A FMN2 MARCHF11 MAPK8IP2	4.98e-06	188	158	7	c4c3b21ab723b0e9beff9ec84f8d68485f771528
ToppCell	5'-Adult-SmallIntestine-Mesenchymal-myocytic-myofibroblast_(RSPO2+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	FLNA FLNC KANK2 AKAP12 MSRB3 FMN2 LTBP1	4.98e-06	188	158	7	879de94924de978478696fc7838e05a4d795b905
ToppCell	3'-Adult-Distal_Rectal-Mesenchymal-Pericytes\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	FLNA ZBTB16 VASN ARHGEF17 MSRB3 RBPMS2 LTBP1	5.16e-06	189	158	7	d69b7a01dd4d6ad043bb6210e9ab34b49578389c
ToppCell	3'-Adult-LargeIntestine-Mesenchymal-myocytic\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	FLNA FRMPD4 MRGPRF KANK2 AKAP12 MSRB3 RBPMS2	5.16e-06	189	158	7	f7e2ee5047792ab9ef6472fa88e2d193cdea6fa0
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	FLNA ZBTB16 ARHGEF17 MSRB3 ACAN RBPMS2 LTBP1	5.16e-06	189	158	7	127ad2ba3e794df8cce2eee3e4171bccb5aad51b
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell-\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	FLNA ZBTB16 ARHGEF17 MSRB3 ACAN RBPMS2 LTBP1	5.16e-06	189	158	7	2cfb4d12f75678d1619f4743838a0e954bd57761
ToppCell	3'-Adult-Distal_Rectal-Mesenchymal-Pericytes-Contractile_pericyte_(PLN+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	FLNA ZBTB16 VASN ARHGEF17 MSRB3 RBPMS2 LTBP1	5.16e-06	189	158	7	2b5f1b4f173a224342ea4f10b193ee33b7662699
ToppCell	3'-Adult-Distal_Rectal-Mesenchymal\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	FLNA ZBTB16 VASN ARHGEF17 MSRB3 RBPMS2 LTBP1	5.16e-06	189	158	7	43e131458d8a4b120f7a5fb3d0c5650abded15f6
ToppCell	PCW_07-8.5-Epithelial-Epithelial_neuroendo-epi_neuroendocrine1[NE1]_(11)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	VWA5B2 GAD2 FRMPD4 ISL1 XKR4 MARCHF11 MAPK8IP2	5.34e-06	190	158	7	b1095b2a7467c152d16e4f19a9515aeb61fc9e3d
ToppCell	3'-GW_trimst-1.5-LargeIntestine-Mesenchymal-myocytic\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	FLNA MRGPRF KANK2 AKAP12 MSRB3 FMN2 LTBP1	5.53e-06	191	158	7	de2cd94ee88a7754f86d39469e38374d668210c7
ToppCell	Mesenchymal-vascular_smooth_muscle_cell\|World / Lineage, Cell type, age group and donor	MRGPRF ARHGEF17 MSRB3 KCNC4 LZTS1 ACAN LTBP1	5.53e-06	191	158	7	fd89fbc62aa1c73e0f659991e3bd726a0c97bd68
ToppCell	PCW_13-14-Mesenchymal-Mesenchymal_myocytic-mes_pericyte_(14)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	FRMPD4 VASN ARHGEF17 KCNC4 LZTS1 ACAN PDZD2	5.72e-06	192	158	7	55f95454399fd533df75db06584eaa48d6ee3830
ToppCell	5'-GW_trimst-1.5-LargeIntestine-Mesenchymal-myocytic\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	FLNA FRMPD4 MRGPRF AKAP12 MSRB3 RBPMS2 LTBP1	5.92e-06	193	158	7	4aa976b596830b585e8d9c808d5072ed23d13a7c
ToppCell	Transplant_Alveoli_and_parenchyma-Mesenchymal-Smooth_muscle\|Transplant_Alveoli_and_parenchyma / Tissue, Lineage and Cell class of Lung Cells from 10X	MRGPRF KANK2 AKAP12 MSRB3 ACAN RBPMS2 LTBP1	5.92e-06	193	158	7	9104b572d9c3c99080e4b7455993fbb944bf117d
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Inner_Medullary_Collecting_Duct_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	FLNB ARHGAP23 ARHGAP30 TACC2 ITPKC SHROOM1 RHOBTB2	5.92e-06	193	158	7	a5695ce2e24a62026ae28f3dea07ca4a435206b8
ToppCell	3'-GW_trimst-1.5-SmallIntestine-Mesenchymal-myocytic\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	FLNA FLNC MRGPRF KANK2 AKAP12 MSRB3 LTBP1	5.92e-06	193	158	7	b1893193766ae41bf2ab6ed4083285c9c814e608
ToppCell	5'-GW_trimst-2-LargeIntestine-Mesenchymal-myocytic-SMC_(PART1/CAPN3+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	FLNA FLNC MRGPRF KANK2 AKAP12 MSRB3 RBPMS2	5.92e-06	193	158	7	0256e8fe4a47f2e2a43ef9d19bfc047d20806d69
ToppCell	Globus_pallidus\|World / BrainAtlas - Mouse McCarroll V32	SZT2 ISL1 CLIC6 MBD6 SLC35D3 RGL2	5.93e-06	126	158	6	44b63f945d5bedf1a2ca1810e7e100276ea9dd89
ToppCell	3'-GW_trimst-1.5-SmallIntestine-Mesenchymal-myocytic-SMC_(PLPP2+)\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	FLNA FLNC MRGPRF KANK2 AKAP12 MSRB3 LTBP1	6.12e-06	194	158	7	bea369e9a7018d862e4d7f1c9ec2de50f3fd38ec
ToppCell	5'-GW_trimst-2-SmallIntestine-Mesenchymal-myocytic-SMC_(PART1/CAPN3+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	FLNA FLNC MRGPRF AKAP12 MSRB3 RBPMS2 LTBP1	6.12e-06	194	158	7	d2bafd31bb8333f66b6c714944bceb2f1aa11740
ToppCell	droplet-Liver-LIVER-NPC-1m-Endothelial-endothelial_cell_of_hepatic_sinusoid\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DDAH2 ARHGAP23 AKAP12 THBD TMCC2 NAV1 FGD5	6.33e-06	195	158	7	f55ab1018a6cde7d517b53e6ce44c3f7bde485c4
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	FLNA MRGPRF ARHGEF17 KANK2 MSRB3 ACAN LTBP1	6.33e-06	195	158	7	e10b21e4dba4483efc4c82d6e395524246ca14a8
ToppCell	droplet-Liver-LIVER-NPC-1m-Endothelial\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DDAH2 ARHGAP23 AKAP12 THBD TMCC2 NAV1 FGD5	6.33e-06	195	158	7	ea1b00805391dca8be0883b635768b296369919a
ToppCell	droplet-Liver-LIVER-NPC-1m-Endothelial-nan\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DDAH2 ARHGAP23 AKAP12 THBD NAV1 ZNRF1 FGD5	6.33e-06	195	158	7	126f46dd15dddcf5701144718bb8ba1ce84b2d1d
ToppCell	droplet-Liver-LIVER-NPC-1m-Endothelial-endothelial_cell_of_hepatic_sinusoid\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DDAH2 ARHGAP23 AKAP12 THBD TMCC2 NAV1 FGD5	6.33e-06	195	158	7	85df110f753f58ab017018c54ee454edb4428e29
ToppCell	TCGA-Prostate-Primary_Tumor-Prostate_Adenocarcinoma-Acinar_Adenocarcinoma-4\|TCGA-Prostate / Sample_Type by Project: Shred V9	ARHGAP23 SH3BP1 CLIC6 ARHGEF17 DENND2B TMCC2 CNN2	6.33e-06	195	158	7	5562665dd3beb70e2358aa32611a337bef5731c1
ToppCell	3'-Broncho-tracheal-Mesenchymal-Mesenchymal_Myocytic\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	FLNA FLNC MRGPRF KANK2 MSRB3 RBPMS2 LTBP1	6.55e-06	196	158	7	92c5be6e43571730c7709046856f6c8ae341a4a1
ToppCell	5'-Adult-SmallIntestine-Mesenchymal-Pericytes-Contractile_pericyte_(PLN+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	FLNA MRGPRF ARHGEF17 KANK2 MSRB3 RBPMS2 LTBP1	6.55e-06	196	158	7	ce6f7ddb8104471dc90347f427486379914d63b4
ToppCell	3'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-tracheobronchial_smooth_muscle_cell\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	FLNA FLNC VASN MRGPRF KANK2 MSRB3 LTBP1	6.55e-06	196	158	7	208ddedd29e1b9ca89cbb9b527c2e193a44cada2
ToppCell	3'-Child04-06-SmallIntestine-Mesenchymal-myocytic\|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	FLNA MRGPRF KANK2 DENND2B AKAP12 MSRB3 LTBP1	6.55e-06	196	158	7	20dc9b25ecc23b6e6e52bbab8b5a404f3245ca37
ToppCell	5'-Adult-SmallIntestine-Mesenchymal-Pericytes\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	FLNA MRGPRF ARHGEF17 KANK2 MSRB3 RBPMS2 LTBP1	6.55e-06	196	158	7	6d7179decea512dd49bb2d5f6a4f5989349d52a9
ToppCell	3'-Broncho-tracheal-Mesenchymal-Mesenchymal_Myocytic-tracheobronchial_smooth_muscle_cell\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	FLNA FLNC MRGPRF KANK2 MSRB3 RBPMS2 LTBP1	6.55e-06	196	158	7	0e7ea6e66bfbb0006ee9651714fe48b0ee194290
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	FLNA MRGPRF ARHGEF17 KANK2 MSRB3 ACAN LTBP1	6.77e-06	197	158	7	d14e1f2ba94240c61eac435db43508a224d606a8
ToppCell	5'-GW_trimst-2-SmallIntestine-Mesenchymal-myocytic\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	FLNA FLNC MRGPRF KANK2 DENND2B MSRB3 CNN2	6.77e-06	197	158	7	94a7270ea6d4b586f58875c9e4071ce0f683ef7e
ToppCell	kidney_cells-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Degenerative_Vascular_Smooth_Muscle_Cell-\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	FLNA FLNC KANK2 MSRB3 ACAN RBPMS2 LTBP1	6.77e-06	197	158	7	aafe279b14cdcb786bc45524bc3c26261128ee48
ToppCell	kidney_cells-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Degenerative_Vascular_Smooth_Muscle_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	FLNA FLNC KANK2 MSRB3 ACAN RBPMS2 LTBP1	6.77e-06	197	158	7	fb14da600f563273059a4683a5079af81aca0886
ToppCell	5'-GW_trimst-1.5-SmallIntestine-Mesenchymal-myocytic\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	FLNA FLNC MRGPRF AKAP12 MSRB3 RBPMS2 LTBP1	6.77e-06	197	158	7	5a63c2b824c7d0dbbc706e408459c9b9fe65daaa
ToppCell	Tracheal-NucSeq-Stromal-Myofibroblastic-Muscle_smooth_pulmonary\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	FLNA FLNC KANK2 AKAP12 MSRB3 ALPK3 LTBP1	6.77e-06	197	158	7	ac4f53acb2f8a428b0f2fab3c30a34e095a1bed7
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Degenerative_Vascular_Smooth_Muscle_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	FLNA ARHGEF17 KANK2 MSRB3 ACAN RBPMS2 LTBP1	6.99e-06	198	158	7	77288df94286382170a266474ab85960519e8449
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Degenerative_Vascular_Smooth_Muscle_Cell-\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	FLNA ARHGEF17 KANK2 MSRB3 ACAN RBPMS2 LTBP1	6.99e-06	198	158	7	2ee195f20a4f91fa1dcad9eaf96d6086e3b0fb4a
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Mesenchymal\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	FLNA MRGPRF ARHGEF17 KANK2 MSRB3 ACAN LTBP1	6.99e-06	198	158	7	54c8aa47040bc4977eed382514fc4ceae03f54f8
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	FRMPD4 XKR6 XKR4 PTPRN2 GLS SCN8A FMN2	6.99e-06	198	158	7	4ca5ff320905ab4ff60ed90a5522227c782142a6
ToppCell	Tracheal-NucSeq-Stromal-Myofibroblastic\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	FLNA FLNC KANK2 MSRB3 ALPK3 LTBP1 PLCL1	6.99e-06	198	158	7	c12e7511628db819a52959bb68580e27c00c2e41
ToppCell	wk_15-18-Mesenchymal-Myofibro_&_SMC\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	FLNA MRGPRF TACC2 ARHGEF17 MSRB3 IL21R LTBP1	6.99e-06	198	158	7	c9c96066c7fa897b583657f0b77ea093920ae9ba
ToppCell	Tracheal-NucSeq-Stromal-Myofibroblastic-Muscle_smooth_airway_ASM\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	FLNA FLNC KANK2 MSRB3 ALPK3 LTBP1 PLCL1	6.99e-06	198	158	7	22e766df1276c5b14aa0d83f434f47140ebb98ea
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Mesenchymal\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	FLNA MRGPRF ARHGEF17 KANK2 MSRB3 ACAN LTBP1	6.99e-06	198	158	7	daf367b699726286f0f0f7b4f3a6cf70c462fbeb
ToppCell	facs-Liver-Non-hepatocytes-3m-Endothelial-endothelial_cell_of_hepatic_sinusoid\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DDAH2 FLNB AKAP12 MSRB3 THBD NAV1 FGD5	6.99e-06	198	158	7	f0f1816a0ed3ae8207442602f5cbe4de0382e4b3
ToppCell	wk_08-11-Mesenchymal-Myofibro_&_SMC-Early_airway_SMC_2\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	FLNA MRGPRF TACC2 MSRB3 IL21R LTBP1 FAM43A	7.23e-06	199	158	7	a207b4891881149d4c50721310690fd794157723
Drug	1-anilino-4-methyl-2-methylthio-4-phenylimidazolin-5-one	FLNA GAD2 FLNB FLNC VASN LRRK1 XKR4 DENND2B MSRB3 CASKIN2 LZTS1 GLS SLC12A7 CNN2	3.31e-07	373	157	14	ctd:C540355
Drug	Cotinine (-) [486-56-6]; Up 200; 22.6uM; MCF7; HT_HG-U133A	MIER2 DNAJB12 USP34 GAD2 SZT2 ARHGEF17 LTBP1 DMRT1 EN2 PDZD2	1.28e-06	199	157	10	1511_UP
Drug	U-62066 [87151-85-7]; Down 200; 1uM; PC3; HT_HG-U133A	DNAJB12 PRSS8 LRRK1 ITPKC CASKIN2 TAF1 EN2 NIPBL CNN2	9.51e-06	197	157	9	4553_DN
Drug	Pyrazinamide [ 98-96-4]; Down 200; 32.4uM; PC3; HT_HG-U133A	PRSS8 IRF2BP1 TRAF3IP1 DSPP LRRK1 TRIM33 CASKIN2 GLS CNN2	1.03e-05	199	157	9	6617_DN
Drug	Fursultiamine Hydrochloride [2105-43-3]; Up 200; 9.2uM; MCF7; HT_HG-U133A	DNAJB12 ARHGEF17 GSPT1 LIG3 CASKIN2 RHOBTB2 GLS SCN8A MBD2	1.07e-05	200	157	9	4975_UP
Disease	myofibrillar myopathy 5 (implicated_via_orthology)	FLNA FLNB FLNC	1.37e-07	3	153	3	DOID:0080096 (implicated_via_orthology)
Disease	distal muscular dystrophy 4 (implicated_via_orthology)	FLNA FLNB FLNC	1.37e-07	3	153	3	DOID:0111190 (implicated_via_orthology)
Disease	myeloid white cell count	BICD2 USP34 GAD2 FLNB ZBTB16 ARHGAP23 SH3BP1 LRRK1 XKR6 DENND2B ZBTB7A UBE2O SLC12A7 MBD2 CNN2	1.14e-04	937	153	15	EFO_0007988
Disease	reticulocyte measurement	USP34 FLNA FLNB GIPC2 CLASP1 ZFPM1 KANK2 DENND2B GSPT1 UBE2O TMCC2 GLS SLC12A7 UBE2Z CUX1 PDZD2	1.22e-04	1053	153	16	EFO_0010700
Disease	Global developmental delay	FRMPD4 SZT2 INTS1 RHOBTB2 TAF1	6.62e-04	133	153	5	C0557874
Disease	FEV/FEC ratio	USP34 GIPC2 TRAF3IP1 DSPP FBXL17 ARHGEF17 DENND2B MSRB3 TRIM33 FCGBP ACAN NAV1 LTBP1 PLCL1 MBD2 CUX1	6.68e-04	1228	153	16	EFO_0004713
Disease	sphingomyelin 16:1 measurement	LZTS1 NKX1-1	7.33e-04	8	153	2	EFO_0010392
Disease	mean reticulocyte volume	ZBTB16 CLASP1 SUSD6 ZFPM1 SH2B1 TRIM33 ZBTB7A TMCC2 SLC7A5 SLC12A7 MBD2 SLC27A5	9.74e-04	799	153	12	EFO_0010701
Disease	age at menopause	FBXL17 ZFPM1 GSPT1 ZBTB7A TNRC18 LRCH4 PLCL1	1.04e-03	302	153	7	EFO_0004704
Disease	type 1 diabetes mellitus (implicated_via_orthology)	GAD2 PTPRN2 MBD2	1.09e-03	39	153	3	DOID:9744 (implicated_via_orthology)
Disease	reticulocyte count	USP34 GAD2 FLNB GIPC2 CLASP1 ZFPM1 KANK2 DENND2B UBE2O TMCC2 GLS UBE2Z CUX1 PDZD2	1.12e-03	1045	153	14	EFO_0007986
Disease	generalized epilepsy with febrile seizures plus 2 (implicated_via_orthology)	SCN4A SCN8A	1.17e-03	10	153	2	DOID:0111294 (implicated_via_orthology)
Disease	Dravet syndrome (implicated_via_orthology)	SCN4A SCN8A	1.17e-03	10	153	2	DOID:0080422 (implicated_via_orthology)
Disease	aortic stenosis, aortic valve calcification	FLNB ACAN NAV1	1.35e-03	42	153	3	EFO_0000266, EFO_0005239
Disease	generalized epilepsy with febrile seizures plus (implicated_via_orthology)	SCN4A SCN8A	1.70e-03	12	153	2	DOID:0060170 (implicated_via_orthology)
Disease	cortical surface area measurement	BICD2 USP34 DDAH2 FLNB ZBTB16 FBXL17 XKR6 AGBL5 MBD6 MSRB3 GLS NAV1 PLCL1 TAF5 CUX1 PDZD2	1.72e-03	1345	153	16	EFO_0010736
Disease	JT interval	ZFPM1 KANK2 LIG3 ALPK3 SLC12A7 CUX1	1.92e-03	248	153	6	EFO_0007885
Disease	QT interval	GIPC2 SYNPO2L KANK2 SH2B1 LIG3 YBX2 ALPK3 SLC12A7 CUX1	1.95e-03	534	153	9	EFO_0004682
Disease	vital capacity	USP34 ZBTB16 DSPP RANBP3 CLIC6 CMSS1 SH2B1 MSRB3 ZBTB7A LZTS1 ACAN SMARCD2 LTBP1 PLCL1 PDZD2	1.98e-03	1236	153	15	EFO_0004312
Disease	myopathy (implicated_via_orthology)	FLNA FLNB FLNC	1.99e-03	48	153	3	DOID:423 (implicated_via_orthology)
Disease	chronotype measurement	USP34 ZBTB16 TRAF3IP1 FBXL17 MADD TRIM33 GLS SCN8A PLCL1 C3orf18 DMRT1 CUX1	2.23e-03	882	153	12	EFO_0008328
Disease	neutrophil count	BICD2 FLNB ZBTB16 COPA ARHGAP23 XKR6 DENND2B AKAP12 TRIM33 TMCC2 PLCL1 SLC12A7 MBD2 UBE2Z CNN2 FAM43A	2.26e-03	1382	153	16	EFO_0004833
Disease	erythrocyte measurement	USP34 KANK2 ZBTB7A TMCC2 SLC7A5 SLC12A7	2.29e-03	257	153	6	EFO_0005047
Disease	autosomal dominant polycystic kidney disease (implicated_via_orthology)	FLNC DNAAF1	2.33e-03	14	153	2	DOID:898 (implicated_via_orthology)
Disease	Dupuytren Contracture	TACC2 LRRK1 ACAN TMCC2	2.45e-03	108	153	4	EFO_0004229
Disease	S-7-hydroxywarfarin measurement	TRADD TACC2 LZTS1 CNN2	2.62e-03	110	153	4	EFO_0803329
Disease	diastolic blood pressure, systolic blood pressure	FBXL17 DENND2B KIAA1671 TRIM33 LIG3 ACAN RBPMS2 NAV1 CUX1 LRRFIP1	2.68e-03	670	153	10	EFO_0006335, EFO_0006336
Disease	basal cell carcinoma	RXFP3 SCAF1 RHOBTB2 TMCC2 CUX1	3.12e-03	189	153	5	EFO_0004193
Disease	cognitive function measurement	DNAJB12 USP34 GIPC2 FRMPD4 CLASP1 SZT2 DSPP FBXL17 SH2B1 THBD KCNC4 PTPRN2 RBPMS2 GCC1 LTBP1 PLCL1	3.25e-03	1434	153	16	EFO_0008354
Disease	alcohol use disorder (implicated_via_orthology)	GAD2 CLIC6 MADD SMARCD2 HR	3.56e-03	195	153	5	DOID:1574 (implicated_via_orthology)
Disease	cutaneous melanoma	FOXQ1 RXFP3 AKAP12 TMCC2	3.69e-03	121	153	4	EFO_0000389
Disease	neuroimaging measurement, brain volume measurement	USP34 XKR6 SH2B1 MSRB3 TMCC2 LRCH4	3.87e-03	286	153	6	EFO_0004346, EFO_0006930
Disease	platelet crit	BICD2 ZBTB16 SUSD6 ZFPM1 DENND2B RBPMS2 FMN2 SLC7A5 SLC12A7 UBE2Z CNN2 CUX1	4.12e-03	952	153	12	EFO_0007985
Disease	osteochondrodysplasia (is_implicated_in)	FLNA FLNB	4.31e-03	19	153	2	DOID:2256 (is_implicated_in)
Disease	abnormal paneth cell measurement	ZBTB16 FBXL17	4.31e-03	19	153	2	EFO_0007963

Protein segments in the cluster

Peptide	Gene	Start	Entry
EDTSLGGDAPADGVS	nan	56	Q6ZR03
ESLSSDGEGVGGGAS	AGBL5	26	Q8NDL9
LAPEAGRADGGTGDS	BICD2	591	Q8TD16
AEGAGLEEGSSLGPG	SH3BP5L	311	Q7L8J4
ETGAQAGSSAIGPEG	ALS2	431	Q96Q42
TAGPLGAEEGTEASA	AKAP12	981	Q02952
EGGGAGTKSVPEDDG	AKAP12	1666	Q02952
DSCDGVEATEGPGSA	CUX1	1336	P39880
GAATAEGGAPEAISG	SH3BP1	666	Q9Y3L3
TGEAAASAGPAVGEG	ALPK3	186	Q96L96
GAGSSPEASDGEGEG	CMSS1	16	Q9BQ75
PGTGEDAGLDNSDGS	DSPP	231	Q9NZW4
EGEPTGAGGGSLSAS	GIPC2	21	Q8TF65
GDTGDSDVTQEGSGP	ATP8B3	26	O60423
DVAGDGDTLGSSEPA	CEP170B	1346	Q9Y4F5
EVPEGSASGEAGDSV	CLIC6	146	Q96NY7
SASGEAGDSVDAEGP	CLIC6	151	Q96NY7
VGDSVDAEGPAGDSV	CLIC6	186	Q96NY7
VGDSVDAEGPAGDSV	CLIC6	226	Q96NY7
VGDSVEAGDPAGDGV	CLIC6	246	Q96NY7
AGDGVEAGVPAGDSV	CLIC6	256	Q96NY7
GSLEEPAGGASVSAG	DENND2B	321	P78524
TDAAGSIATATPDGG	NAGK	106	Q9UJ70
SAGGSSPEGGEDSDR	RANBP3	96	Q9H6Z4
APSGATAAGAGDEGD	RANBP3	546	Q9H6Z4
TGSGAGSGGALEEEV	RBPMS2	16	Q6ZRY4
TGGPSASAGKAEDEG	PAGR1	36	Q9BTK6
SEDDVVAGGGGASDP	ITPKC	366	Q96DU7
VAGGGGASDPEDRSG	ITPKC	371	Q96DU7
KDGPGETDAFGNSEG	GLS	106	O94925
LSGLGGDPGADATAA	PTPRN2	651	Q92932
AGGEEAAATTSVPGS	LRCH4	11	O75427
GGTAGVGLEAAEPTA	NR1H3	51	Q13133
DGSAGTRDGGVLPAA	ARHGEF17	96	Q96PE2
AESPGGASESDQDGG	PNMA8A	326	Q86V59
FGSEDGSGDSENPGT	GAD2	11	Q05329
LGPTAGDGEGSAEGA	MBD6	631	Q96DN6
GDSTSDAEGDAGPAG	TRAF3IP1	421	Q8TDR0
ADSDLSSNAGDGPGG	MADD	1211	Q8WXG6
SSGDLGGQAGVDFDP	LZTS1	86	Q9Y250
VADEGSGPTAGDMAG	KIAA1671	301	Q9BY89
EAGRVAGDLGAGSSP	INTS1	271	Q8N201
SEDEGSVLGQGGSGT	LRRK1	1241	Q38SD2
SPGSDSEDAGGARLG	MAPK8IP2	251	Q13387
DAEDSAGSPGGRGTG	MAPK8IP2	481	Q13387
AGVESGAASEAPGGR	LBHD1	216	Q9BQE6
EGSSPGEDSSSLGGG	LMTK3	646	Q96Q04
PDSRAGGDTALSGDG	LMTK3	1181	Q96Q04
PSEAGSQDSGDGAVG	DYNC1I2	96	Q13409
DTRIPDAAGGTAGVG	C3orf18	46	Q9UK00
EGLEGGASGASEPSE	HR	346	O43593
VSEAEPGGGSSGDSG	GSPT2	156	Q8IYD1
AGPGALGLEAVSDSG	FLNB	1161	O75369
AGGRGPSGAEEATVE	PLXNB3	336	Q9ULL4
RADGAAPAGEGEGVT	SLC7A5P1	31	Q8MH63
GFVPAGESSSEAGGE	LTBP1	1406	Q14766
AAEVPGSEGGSATGE	PCDH8	846	O95206
SGLGFSVAGGTDVEP	PDZD2	2631	O15018
GSESSNDGGSESPGD	PGRMC2	16	O15173
GAGAGAGEESPATSL	PGRMC2	81	O15173
PGAGALSREGEEGTD	FGD5	126	Q6ZNL6
DAGEGGLSLAVEGPS	FLNC	1886	Q14315
AATPEDGAGGRGSEG	ZFPM1	651	Q8IX07
ESDGEDRGGGTSGSL	NIPBL	2671	Q6KC79
SADGSAPAGEGEGVT	SLC7A5	31	Q01650
AGSGAEDVGPGGEDV	GOLGA6L2	566	Q8N9W4
SGGAEEPRGSESAAA	GOLGA6L4	496	A6NEF3
RADGAAPAGEGEGVT	SLC7A5P2	31	Q9GIP4
GGSSEENKGPSGSAV	LIG3	851	P49916
AEGEAEGPVGSTLGS	CASKIN2	811	Q8WXE0
EISEAEPGGGSLGDG	GSPT1	26	P15170
PEGSETSFVDSGVGG	MTMR4	651	Q9NYA4
SGAPDVSGDFTGSGD	ACAN	861	P16112
CPEQEEGESAAGGSG	MBD2	11	Q9UBB5
SSSSGDGPFAGGEVD	GCC1	141	Q96CN9
EESGASGSDSGGSPL	CASC3	16	O15234
FLSGGTDGQDGPTEA	GLYCTK	446	Q8IVS8
SRGGAGGEASDPESA	CCDC106	121	Q9BWC9
FGGPDACGVISATDG	FCGBP	3461	Q9Y6R7
SAAGAAPGGGVDTRD	FLNA	11	P21333
PEGGADSSGVGAEAE	ATPAF1	56	Q5TC12
ELDISPGAAGGAEDG	COPA	891	P53621
EGAPDGETSDGSGLG	FRMPD4	1131	Q14CM0
TSEGAPTEAGGDAVR	FBXL17	266	Q9UF56
PTEAGGDAVRAGGTA	FBXL17	271	Q9UF56
GTDAPSANGEAGGES	DNAJB12	76	Q9NXW2
EGSQGTAEADGPGAS	CENPT	371	Q96BT3
GPGASSGDEDASGRA	CENPT	381	Q96BT3
GGGDSLEVDGVAATP	AKNA	791	Q7Z591
STGSESSIEGGGPDA	FAM43A	386	Q8N2R8
EAAAAKGGPGESEAG	MARCHF11	111	A6NNE9
GSVGFGGSPDELGET	AGA	71	P20933
EPGVEESAGDHGSAG	DNAAF1	21	Q8NEP3
EAGAEVLSAGDGPGA	FAM98C	61	Q17RN3
AASQESEEAGGTGGP	KANK2	461	Q63ZY3
GGVSESEAGSPLAGL	IL21R	471	Q9HBE5
AGAEPGDSGGDEAVA	CCDC177	11	Q9NQR7
AGSDSPGDGEGGSKT	EN2	146	P19622
GEIRGDTGGEDTAAP	DCTPP1	6	Q9H773
ESLASGEGAGAGLPA	DDAH2	21	O95865
GEEAAGAPVRGAGDT	FMN2	331	Q9NZ56
GGGDETAERTEAPGT	SLC12A7	16	Q9Y666
AADSASGEVGNPLGG	DMRT1	236	Q9Y5R6
EVSPTAGAEAVSGGG	IRF2BP1	476	Q8IU81
QGSDLEGAGGSDAPS	FOXQ1	16	Q9C009
SSGPRAGGEELDEGV	LRRFIP1	686	Q32MZ4
GTAGGLDEPGVASDG	MIER2	406	Q8N344
RSPEAATEGGAGEVS	ARHGAP30	821	Q7Z6I6
SLTDFLAEDGGTGGG	EIF4B	16	P23588
SSGGGDEGADEPRGA	NAV1	16	Q8NEY1
EDPGAAAGGSVRGSG	SMG8	106	Q8ND04
EPEAAVPASGTGGES	GOLGA8A	431	A7E2F4
PGSGGAESADTEARV	RXFP3	66	Q9NSD7
GGAESGPEEDALSLG	SYNPO2L	666	Q9H987
AVAGSGAPGEVDSAG	TAF5	126	Q15542
GAPGEVDSAGAEVTS	TAF5	131	Q15542
GGSSGSDSEGPNDTL	SZT2	1871	Q5T011
GSPLSGGAEEASGGT	RGL2	621	O15211
EAIAPGSEAQGAGSG	SH2B1	706	Q9NRF2
SEGGEAAGGPAQESR	SLC35D3	346	Q5M8T2
GPDDGGVAAASSGSA	TRIM33	61	Q9UPN9
DSGKVDGGDSGSGEP	THBD	481	P07204
ADGAGEAGEAGETAP	SCN4A	861	P35499
GETTGANSAGGPTSD	TMCC2	36	O75069
SGARGGDGEVASAPL	TRADD	166	Q15628
GGGGHSPSADSGDEV	NKX1-1	176	Q15270
DGAELGEAGGSTPNT	MRGPRF	316	Q96AM1
TAAVPGDPGATDTDG	TAF11	21	Q15544
EEDSSGGGPFTLAGI	TAF1L	26	Q8IZX4
SDEDSAGGGPFSLAG	TAF1	26	P21675
PGALGSGGSAEDSVG	PTPRCAP	16	Q14761
VDEAGGSGPAGLRAS	RHOBTB2	351	Q9BYZ6
GEAGEEAASTFEPGS	SHROOM1	591	Q2M3G4
SSAEDGEGSDGPGGK	SAMD14	56	Q8IZD0
EGGPGSNSTGSEVAS	ISL1	316	P61371
FTPADSSGTAEGGSG	MSRB3	166	Q8IXL7
SGTGAEGAEAPCGVA	PRSS8	26	Q16651
GACSSAGGEDEAPGQ	SUSD6	221	Q92537
KAEGDSAGTAGTPGG	SMARCD2	206	Q92925
AASPATEGRGGSEVE	CLASP1	1221	Q7Z460
QGTVADGAPSGTGDC	CNN2	276	Q99439
TGEGKDGGTAGSEEP	TNRC18	2311	O15417
DGGTAGSEEPGAKAR	TNRC18	2316	O15417
GPDAAGDCVTAASGG	PLCL1	26	Q15111
ETGEGSAGASGAPEK	SHF	116	Q7M4L6
SAGTGPGSKGERAED	YBX2	201	Q9Y2T7
GGGDGSEPGESSSMH	XKR6	41	Q5GH73
SDGSPLSESGGENGT	UBN2	416	Q6ZU65
SPGAAESSISGGMGD	ZBTB16	256	Q05516
DSGEGSAGEGERAAP	SLC27A3	121	Q5K4L6
SAGEGERAAPGAGDA	SLC27A3	126	Q5K4L6
TGPGAGSVTFGELDA	SLC27A5	136	Q9Y2P5
GTDPGTETEESMGGG	TPR	2011	P12270
AGSTAGDSGAEDGPA	SCAF1	1061	Q9H7N4
ETDTEGAAGAGPGGR	ARHGAP23	1286	Q9P227
LGAGDSSGEPGAEEA	STYXL2	561	Q5VZP5
EGGAESPGAESLRVG	TMEM79	36	Q9BSE2
SSAGSPTAIEGAEDG	TMEM79	51	Q9BSE2
APGEASQGSDSEGGA	UBE2O	1191	Q9C0C9
VGGGSAAGEGEARPS	XKR4	196	Q5GH76
EGEEGGGSPRSSSEI	SCN8A	466	Q9UQD0
EGASRETAGGGPSEG	SERPINE3	156	A8MV23
DSESAEGVVPPASGG	TACC2	2206	O95359
TEEAATAGAGAAGPG	UBE2Z	6	Q9H832
KATEGGGEALPSGSE	VASN	636	Q6EMK4
GDGEGPGDVTAGVSR	UNQ6494/PRO21346	41	Q6UXR6
GPGQVDSGRGSDTEA	VWA5B2	1136	Q8N398
SSSGDSAGLEAGQGP	ZSCAN18	386	Q8TBC5
SEDTAAASAGDGPGV	ZNF687	51	Q8N1G0
DETANSGEDGSSGPG	USP34	566	Q70CQ2
ESPGVGGGSGDEASA	ZBTB22	591	O15209
AGAAEEEESGLPGAG	WDR81	1026	Q562E7
DSERAPGGGGSASDS	ZNRF1	81	Q8ND25
GDSPGFLSGAAEGED	ZBTB7A	291	O95365
DEEVSGAGSSPVSGG	TRIR	41	Q9BQ61
EALDIFESPDGGGSG	KCNC4	156	Q03721
SPGDDGDGRAEGFSL	MUC12	116	Q9UKN1