Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionglycogen phosphorylase activity

PYGB PYGL PYGM

3.30e-0731393GO:0008184
GeneOntologyMolecularFunction1,4-alpha-oligoglucan phosphorylase activity

PYGB PYGL PYGM

3.27e-0651393GO:0004645
GeneOntologyMolecularFunctionmicrofilament motor activity

MYH1 MYH4 MYH8 MYO15A

1.38e-04381394GO:0000146
GeneOntologyCellularComponentmyosin filament

MYH1 MYH4 MYH8 MYBPC2

2.19e-05251404GO:0032982
GeneOntologyCellularComponentmyosin II complex

MYH1 MYH4 MYH8 MYL12B

3.48e-05281404GO:0016460
GeneOntologyCellularComponentmyosin complex

MYH1 MYH4 MYH8 MYO15A MYL12B

4.70e-05591405GO:0016459
GeneOntologyCellularComponentsarcomere

MYH1 MYH4 MYH8 NRAP SPTAN1 MYLK2 PYGM MYL12B MYBPC2

4.72e-052491409GO:0030017
GeneOntologyCellularComponentmyofibril

MYH1 MYH4 MYH8 NRAP SPTAN1 MYLK2 PYGM MYL12B MYBPC2

9.56e-052731409GO:0030016
GeneOntologyCellularComponentcontractile muscle fiber

MYH1 MYH4 MYH8 NRAP SPTAN1 MYLK2 PYGM MYL12B MYBPC2

1.51e-042901409GO:0043292
GeneOntologyCellularComponentmuscle myosin complex

MYH1 MYH4 MYH8

1.54e-04161403GO:0005859
DomainPHOSPHORYLASE

PYGB PYGL PYGM

3.95e-0731383PS00102
DomainGlycg_phsphrylas

PYGB PYGL PYGM

3.95e-0731383IPR011833
DomainGlyco_trans_35

PYGB PYGL PYGM

3.95e-0731383IPR000811
DomainPhosphorylase

PYGB PYGL PYGM

3.95e-0731383PF00343
DomainTPR-like_helical_dom

SAMD9 RPAP3 TTC3 TTC6 SMYD4 TRANK1 LONRF3 CDC27 CDC23 CRTAP

9.24e-0623313810IPR011990
DomainTPR

RPAP3 TTC3 TTC6 TRANK1 LONRF3 CDC27 CDC23

4.87e-051291387SM00028
Domain-

NARF CIAO3

5.42e-05213824.10.260.20
DomainFe_hydrogenase_lsu_C

NARF CIAO3

5.42e-0521382IPR004108
DomainFe_hyd_lg_C

NARF CIAO3

5.42e-0521382PF02906
DomainFe_hyd_SSU

NARF CIAO3

5.42e-0521382PF02256
DomainFe_hyd_SSU

NARF CIAO3

5.42e-0521382SM00902
DomainFe_hydrogenase_ssu

NARF CIAO3

5.42e-0521382IPR003149
DomainTPR-contain_dom

RPAP3 TTC3 TTC6 TRANK1 LONRF3 CDC27 CDC23

1.26e-041501387IPR013026
DomainFe_hydrogenase

NARF CIAO3

1.62e-0431382IPR009016
DomainMyosin_N

MYH1 MYH4 MYH8

1.68e-04151383PF02736
DomainMyosin_N

MYH1 MYH4 MYH8

1.68e-04151383IPR004009
DomainMyosin_head_motor_dom

MYH1 MYH4 MYH8 MYO15A

1.73e-04381384IPR001609
DomainMYOSIN_MOTOR

MYH1 MYH4 MYH8 MYO15A

1.73e-04381384PS51456
DomainMyosin_head

MYH1 MYH4 MYH8 MYO15A

1.73e-04381384PF00063
DomainMYSc

MYH1 MYH4 MYH8 MYO15A

1.73e-04381384SM00242
DomainTPR_REGION

RPAP3 TTC3 TTC6 TRANK1 LONRF3 CDC27 CDC23

2.27e-041651387PS50293
DomainTPR

RPAP3 TTC3 TTC6 TRANK1 LONRF3 CDC27 CDC23

2.27e-041651387PS50005
DomainMyosin_tail_1

MYH1 MYH4 MYH8

2.97e-04181383PF01576
DomainMyosin_tail

MYH1 MYH4 MYH8

2.97e-04181383IPR002928
DomainRNase_II/R_CS

DIS3L2 HELZ2

3.22e-0441382IPR022966
DomainIQ

MYH1 MYH4 MYH8 RASGRF2 MYO15A

3.34e-04811385SM00015
DomainMyosin-like_IQ_dom

MYH1 MYH4 MYH8

3.51e-04191383IPR027401
Domain-

MYH1 MYH4 MYH8

3.51e-041913834.10.270.10
DomainEGF_3

FAT4 CNTNAP3 VWDE FAT1 JAG1 LRP5 C6 TNXB

3.64e-042351388PS50026
DomainTPR_repeat

RPAP3 TTC3 TRANK1 LONRF3 CDC27 CDC23

4.64e-041331386IPR019734
DomainEGF-like_dom

FAT4 CNTNAP3 VWDE FAT1 JAG1 LRP5 C6 TNXB

5.34e-042491388IPR000742
DomainFYrich_C

KMT2C KMT2D

5.34e-0451382IPR003889
DomainFYrich_N

KMT2C KMT2D

5.34e-0451382IPR003888
DomainFYRC

KMT2C KMT2D

5.34e-0451382SM00542
DomainFYRN

KMT2C KMT2D

5.34e-0451382SM00541
DomainFYRN

KMT2C KMT2D

5.34e-0451382PF05964
DomainFYRC

KMT2C KMT2D

5.34e-0451382PF05965
DomainFYRC

KMT2C KMT2D

5.34e-0451382PS51543
DomainFYRN

KMT2C KMT2D

5.34e-0451382PS51542
DomainTPR_1

RPAP3 TTC3 TTC6 CDC27 CDC23

5.44e-04901385IPR001440
DomainTPR_1

RPAP3 TTC3 TTC6 CDC27 CDC23

5.44e-04901385PF00515
DomainIQ_motif_EF-hand-BS

MYH1 MYH4 MYH8 RASGRF2 MYO15A

5.44e-04901385IPR000048
DomainEGF_1

FAT4 CNTNAP3 VWDE FAT1 JAG1 LRP5 C6 TNXB

6.24e-042551388PS00022
DomainIQ

MYH1 MYH4 MYH8 RASGRF2 MYO15A

6.32e-04931385PS50096
DomainEGF-like_CS

FAT4 CNTNAP3 VWDE FAT1 JAG1 LRP5 C6 TNXB

7.26e-042611388IPR013032
DomainEGF_2

FAT4 CNTNAP3 VWDE FAT1 JAG1 LRP5 C6 TNXB

8.02e-042651388PS01186
Domain-

RPAP3 TTC3 SMYD4 TRANK1 LONRF3 CDC23 CRTAP

8.84e-0420713871.25.40.10
DomainEGF

FAT4 CNTNAP3 VWDE FAT1 JAG1 LRP5 TNXB

1.83e-032351387SM00181
DomainIQ

MYH1 MYH4 MYH8 MYO15A

1.89e-03711384PF00612
DomainEGF

CNTNAP3 FAT1 JAG1 LRP5 TNXB

2.45e-031261385PF00008
PathwayKEGG_MEDICUS_REFERENCE_GLYCOGEN_DEGRADATION

PYGB PYGL PYGM

2.91e-0591013M47621
Pubmed

During muscle atrophy, thick, but not thin, filament components are degraded by MuRF1-dependent ubiquitylation.

MYH1 MYH4 MYH8 MYBPC2

5.33e-0810141419506036
Pubmed

Three linked myosin heavy chain genes clustered within 370 kb of each other show independent transcriptional and post-transcriptional regulation during differentiation of a mouse muscle cell line.

MYH1 MYH4 MYH8

2.60e-07414131985022
Pubmed

A Degradation Motif in STAU1 Defines a Novel Family of Proteins Involved in Inflammation.

AKAP8 MAP7D3 RPAP3 SPTAN1 PPA1 HMMR TTC3 DHX8 PDIA4 FARP1 CDC27 MGA MYL12B CNOT1 YTHDF3

2.81e-077241411536232890
Pubmed

Developmental pattern of mouse skeletal myosin heavy chain gene transcripts in vivo and in vitro.

MYH1 MYH4 MYH8

6.48e-07514133829126
Pubmed

Myosin heavy chain isoforms of the murine masseter muscle during pre- and post-natal development.

MYH1 MYH4 MYH8

6.48e-075141312919077
Pubmed

Sequential accumulation of mRNAs encoding different myosin heavy chain isoforms during skeletal muscle development in vivo detected with a recombinant plasmid identified as coding for an adult fast myosin heavy chain from mouse skeletal muscle.

MYH1 MYH4 MYH8

6.48e-07514136196357
Pubmed

FBXO22 promotes leukemogenesis by targeting BACH1 in MLL-rearranged acute myeloid leukemia.

RASGRF2 CDKN2AIP HMMR TTC6 KMT2C TRANK1 LOXHD1 UBA6 HERC1 MMP19 CNOT1 CDC23

9.57e-074971411236774506
Pubmed

Distinct myogenic programs of embryonic and fetal mouse muscle cells: expression of the perinatal myosin heavy chain isoform in vitro.

MYH1 MYH4 MYH8

1.29e-06614131728586
Pubmed

Organization of human and mouse skeletal myosin heavy chain gene clusters is highly conserved.

MYH1 MYH4 MYH8

1.29e-066141310077619
Pubmed

Spatial and temporal changes in myosin heavy chain gene expression in skeletal muscle development.

MYH1 MYH4 MYH8

1.29e-066141310588881
Pubmed

A fast Myosin super enhancer dictates muscle fiber phenotype through competitive interactions with Myosin genes.

MYH1 MYH4 MYH8

2.26e-067141335210422
Pubmed

Diversity in transcriptional start site selection and alternative splicing affects the 5'-UTR of mouse striated muscle myosin transcripts.

MYH1 MYH4 MYH8

2.26e-067141316819597
Pubmed

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.

RTN3 GRIK1 PTEN TTC3 HNRNPL TASOR2 CUL5 ZNF708 PACS1 KMT2C INTS6 PTPRJ PCNX4 FARP1 UBA6 LRP5 ZFHX3 CATSPERG PCCA CNOT1

2.60e-0614891412028611215
Pubmed

Genes for skeletal muscle myosin heavy chains are clustered and are not located on the same mouse chromosome as a cardiac myosin heavy chain gene.

MYH1 MYH4 MYH8

3.60e-06814133864153
Pubmed

Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.

DNHD1 ADCY4 VRK1 NOC2L SPTAN1 RTN3 PPA1 TTC3 HNRNPL DHX8 PDIA4 FARSA RPRD1A EIF2B1 TIMM50 UBA6 TOMM40 MTREX CNOT1

5.26e-0614251411930948266
Pubmed

Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.

RPAP3 CDKN2AIP SPTAN1 PTEN BIRC6 HNRNPL PDIA4 PACS1 KMT2D PTPRJ LNPEP FARP1 TIMM50 ROCK1 HERC1 CNOT1

5.95e-0610491411627880917
Pubmed

Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.

CASP8AP2 RPAP3 BIRC6 KMT2D ZFHX4 ZFHX3 MGA PCCA CNOT1 CDC23

8.62e-064181411034709266
Pubmed

Modulation of contractile protein gene expression in fetal murine crural muscles: emergence of muscle diversity.

MYH1 MYH4 MYH8

1.05e-051114138136524
Pubmed

LGALS3BP regulates centriole biogenesis and centrosome hypertrophy in cancer cells.

MAP7D3 SPTAN1 MMP27 PEX1 GPATCH8 FAT1 RPRD1A ZNF804B TIMM50 CDC27 MYL12B CDC23

1.24e-056391411223443559
Pubmed

Targeting USP10 induces degradation of oncogenic ANLN in esophageal squamous cell carcinoma.

SAMD9 AKAP8 MAP7D3 RPAP3 NOC2L SPTAN1 HMMR ARPC3 HNRNPL TASOR2 DHX8 FARSA TIMM50 HELZ2 TOMM40 MTREX MYL12B

1.43e-0512571411736526897
Pubmed

KMT2C/D COMPASS complex-associated diseases [KCDCOM-ADs]: an emerging class of congenital regulopathies.

KMT2C KMT2D

1.63e-052141231924266
Pubmed

Growth and muscle defects in mice lacking adult myosin heavy chain genes.

MYH1 MYH4

1.63e-05214129382868
Pubmed

Postnatal myosin heavy chain isoform expression in normal mice and mice null for IIb or IId myosin heavy chains.

MYH1 MYH4

1.63e-052141211150240
Pubmed

The mouse ZFH-4 protein contains four homeodomains and twenty-two zinc fingers.

ZFHX4 ZFHX3

1.63e-052141210873665
Pubmed

Histone H3K4 monomethylation catalyzed by Trr and mammalian COMPASS-like proteins at enhancers is dispensable for development and viability.

KMT2C KMT2D

1.63e-052141228967912
Pubmed

Additive Effect of Zfhx3/Atbf1 and Pten Deletion on Mouse Prostatic Tumorigenesis.

PTEN ZFHX3

1.63e-052141226233892
Pubmed

Inactivation of PTEN and ZFHX3 in Mammary Epithelial Cells Alters Patterns of Collective Cell Migration.

PTEN ZFHX3

1.63e-052141236613756
Pubmed

ROCK1 functions as a suppressor of inflammatory cell migration by regulating PTEN phosphorylation and stability.

PTEN ROCK1

1.63e-052141220008297
Pubmed

Association of KMT2C/D loss-of-function variants with response to immune checkpoint blockades in colorectal cancer.

KMT2C KMT2D

1.63e-052141236601880
Pubmed

Mll3 and Mll4 Facilitate Enhancer RNA Synthesis and Transcription from Promoters Independently of H3K4 Monomethylation.

KMT2C KMT2D

1.63e-052141228483418
Pubmed

CKD Stimulates Muscle Protein Loss Via Rho-associated Protein Kinase 1 Activation.

PTEN ROCK1

1.63e-052141226054539
Pubmed

The MLL3/4 H3K4 methyltransferase complex in establishing an active enhancer landscape.

KMT2C KMT2D

1.63e-052141234156443
Pubmed

Five skeletal myosin heavy chain genes are organized as a multigene complex in the human genome.

MYH4 MYH8

1.63e-05214128518795
Pubmed

Reduced Expression of Histone Methyltransferases KMT2C and KMT2D Correlates with Improved Outcome in Pancreatic Ductal Adenocarcinoma.

KMT2C KMT2D

1.63e-052141227280393
Pubmed

Loss of MLL3/4 decouples enhancer H3K4 monomethylation, H3K27 acetylation, and gene activation during embryonic stem cell differentiation.

KMT2C KMT2D

1.63e-052141236869380
Pubmed

GNAO1 organizes the cytoskeletal remodeling and firing of developing neurons.

SPTAN1 GNAO1

1.63e-052141233107105
Pubmed

Isoform-selective regulation of glycogen phosphorylase by energy deprivation and phosphorylation in astrocytes.

PYGB PYGM

1.63e-052141225130497
Pubmed

Crucial roles of mixed-lineage leukemia 3 and 4 as epigenetic switches of the hepatic circadian clock controlling bile acid homeostasis in mice.

KMT2C KMT2D

1.63e-052141225346535
Pubmed

Skeletal muscle adaptations in response to voluntary wheel running in myosin heavy chain null mice.

MYH1 MYH4

1.63e-052141211744674
Pubmed

Synthetic Lethal and Resistance Interactions with BET Bromodomain Inhibitors in Triple-Negative Breast Cancer.

CASP8AP2 VRK1 CDKN2AIP PPA1 GPATCH8 CUL5 FARSA UBE2T EIF2B1 UBA6 PYGB PYGL MTREX MYO15A CDC23

1.69e-0510141411532416067
Pubmed

Contractile protein gene expression in primary myotubes of embryonic mouse hindlimb muscles.

MYH1 MYH4 MYH8

1.81e-051314138404542
Pubmed

Large-scale mapping of human protein-protein interactions by mass spectrometry.

MYH4 RASGRF2 NOC2L ALG11 GPATCH8 ARPC3 HNRNPL CUL5 PDIA4 KMT2C LOXHD1 EIF2B1 TIMM50 PYGM HERC1 MTREX CNOT1

1.88e-0512841411717353931
Pubmed

Defective excitation-contraction coupling is partially responsible for impaired contractility in hindlimb muscles of Stac3 knockout mice.

MYH1 MYH4 MYH8

2.30e-0514141327184118
Pubmed

Voltage-dependent conformational changes of Kv1.3 channels activate cell proliferation.

DNHD1 DOCK10 KMT2C CCDC62 PKHD1 PYGL CNOT1

2.37e-05208141733230847
Pubmed

An organelle-specific protein landscape identifies novel diseases and molecular mechanisms.

MAP7D3 RPAP3 PFKFB2 PPA1 HMMR ARPC3 CDR2L TBC1D32 PACS1 RPRD1A EIF2B1 PYGL LUM CDC27 MYL12B CNOT1 CDC23

2.69e-0513211411727173435
Pubmed

Localization of the muscle, liver, and brain glycogen phosphorylase genes on linkage maps of mouse chromosomes 19, 12, and 2, respectively.

PYGB PYGL PYGM

2.86e-051514132575583
Pubmed

Abnormal Mammary Development in 129:STAT1-Null Mice is Stroma-Dependent.

MYH1 MYH4 PYGM MYBPC2

3.10e-0544141426075897
Pubmed

Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.

OGFRL1 PEX1 GPATCH8 TTC3 PDIA4 PACS1 KMT2C FARP1 ROCK1 HERC1 CDC27 MGA CNOT1 YTHDF3 LRRC17

3.64e-0510841411511544199
Pubmed

The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.

AKAP8 NOC2L CDKN2AIP HMMR GPATCH8 ARPC3 MYLK2 DHX8 KMT2C INTS6 FARSA LNPEP FARP1 HELZ2 ZFHX3 TOMM40 MTREX CDC27

3.74e-0514971411831527615
Pubmed

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

AKAP8 SPTAN1 TRPC4 TTC3 ARPC3 FARSA FARP1 KCNJ16 UBA6 ELAVL4 ROCK1 GNAO1 MGA CNOT1

3.96e-059631411428671696
Pubmed

Proteome-wide identification of HSP70/HSC70 chaperone clients in human cells.

VRK1 PPA1 HMMR SERPINA12 HNRNPL PDIA4 UBE2T TIMM50 UBA6 PYGB PYGL ROCK1 GNAO1 CDC27 PCCA MYL12B CNOT1

4.12e-0513671411732687490
Pubmed

Large-scale analysis of the human ubiquitin-related proteome.

MYH1 PFKFB2 BIRC6 HNRNPL FARSA UBE2T TIMM50 PYGL

4.42e-05313141816196087
Pubmed

An antibody-based proximity labeling map reveals mechanisms of SARS-CoV-2 inhibition of antiviral immunity.

AKAP8 RPAP3 SHC4 GPATCH8 BIRC6 DHX8 PDIA4 FARSA EIF2B1 ROCK1 MGA YTHDF3

4.71e-057331411234672954
Pubmed

Transition of myosin heavy chain isoforms in human laryngeal abductors following denervation.

MYH1 MYH4

4.88e-053141226059207
Pubmed

PTEN mediates Notch-dependent stalk cell arrest in angiogenesis.

PTEN JAG1

4.88e-053141226228240
Pubmed

Simultaneous loss of skeletal muscle myosin heavy chain IIx and IIb causes severe skeletal muscle hypoplasia in postnatal mice.

MYH1 MYH4

4.88e-053141236515178
Pubmed

Incentive learning underlying cocaine-seeking requires mGluR5 receptors located on dopamine D1 receptor-expressing neurons.

DRD1 GRIK1

4.88e-053141220826661
Pubmed

Remodeling of the enhancer landscape during macrophage activation is coupled to enhancer transcription.

KMT2C KMT2D

4.88e-053141223932714
Pubmed

Mutations of PTCH1, MLL2, and MLL3 are not frequent events in hepatoblastoma.

KMT2C KMT2D

4.88e-053141222183980
Pubmed

Aging-related dysregulation of dopamine and angiotensin receptor interaction.

DRD1 AGTR1

4.88e-053141224529758
Pubmed

The dopaminergic D1 receptor modulates the hyperactivity of Bapa mutant mice.

DRD1 KMT2D

4.88e-053141237394124
Pubmed

The RhoA-ROCK-PTEN pathway as a molecular switch for anchorage dependent cell behavior.

PTEN ROCK1

4.88e-053141222244698
Pubmed

HOXC6 Is transcriptionally regulated via coordination of MLL histone methylase and estrogen receptor in an estrogen environment.

KMT2C KMT2D

4.88e-053141221683083
Pubmed

Radiogenomics in head and neck cancer: correlation of radiomic heterogeneity and somatic mutations in TP53, FAT1 and KMT2D.

FAT1 KMT2D

4.88e-053141231123786
Pubmed

Differential D1 and D5 receptor regulation and degradation of the angiotensin type 1 receptor.

DRD1 AGTR1

4.88e-053141218172057
Pubmed

KMT2C methyltransferase domain regulated INK4A expression suppresses prostate cancer metastasis.

PTEN KMT2C

4.88e-053141235354467
Pubmed

Expression of AT1R, AT2R and AT4R and their roles in extravillous trophoblast invasion in the human.

LNPEP AGTR1

4.88e-053141220304486
Pubmed

E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.

MYH1 MYH4 FAT4 BIRC6 HNRNPL KMT2C LOXHD1 R3HCC1L PKHD1 SNX31 C6 CNOT1

4.89e-057361411229676528
Pubmed

Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes.

VRK1 AKAP8 MAP7D3 NOC2L HNRNPL TBC1D32 KMT2D ZFHX4 CCDC15 TOMM40 CDC27 MGA MYL12B

4.92e-058571411325609649
Pubmed

A global genomic transcriptional code associated with CNS-expressed genes.

VRK1 ACADSB TTC3 ZFHX4 PKHD1 ELAVL4 ZFHX3 PCCA

4.94e-05318141816919269
Pubmed

USP7 targets XIAP for cancer progression: Establishment of a p53-independent therapeutic avenue for glioma.

DNHD1 SERPINA12 HNRNPL CDR2L KMT2D HERC1 MTREX

5.02e-05234141736243803
Pubmed

ALS/FTD-causing mutation in cyclin F causes the dysregulation of SFPQ.

MAP7D3 PPA1 TTC3 HNRNPL TASOR2 PDIA4 FARSA MTREX PCCA MYL12B CDC23

5.10e-056241411133729478
Pubmed

NudCL2 regulates cell migration by stabilizing both myosin-9 and LIS1 with Hsp90.

DIS3L2 DAPL1 CDKN2AIP SPTAN1 ARPC3 TTC6 HNRNPL DMXL1

6.82e-05333141832665550
Pubmed

Host E3 ligase HUWE1 attenuates the proapoptotic activity of the MERS-CoV accessory protein ORF3 by promoting its ubiquitin-dependent degradation.

RPAP3 PPA1 BIRC6 CUL5 PDIA4 FARSA TIMM50 PYGB CDC27 CNOT1

6.87e-055341411035032548
Pubmed

Cyclical expression of the Notch/Wnt regulator Nrarp requires modulation by Dll3 in somitogenesis.

HNRNPL ITIH5 ELAVL4

7.07e-0520141319268448
Pubmed

Human transcription factor protein interaction networks.

AKAP8 SPTAN1 GPATCH8 ARPC3 HNRNPL PDIA4 KMT2C FAT1 KMT2D ZFHX4 TIMM50 ZFHX3 HERC1 MGA PCCA CNOT1 YTHDF3

7.11e-0514291411735140242
Pubmed

Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.

SAMD9 RPAP3 DOCK10 PEX1 HMMR FHIP2A CUL5 PACS1 SMYD4 PYGB MTREX

7.33e-056501411138777146
Pubmed

Systematic analysis of human protein complexes identifies chromosome segregation proteins.

SCFD2 AKAP8 CDKN2AIP HMMR TASOR2 PDIA4 PACS1 TIMM50 CCDC15 PYGM GNAO1 CDC27 CNOT1 CDC23 CRTAP

7.44e-0511551411520360068
Pubmed

H4K20me0 recognition by BRCA1-BARD1 directs homologous recombination to sister chromatids.

CASP8AP2 AKAP8 MAP7D3 NOC2L GPATCH8 HNRNPL DHX8 KMT2C INTS6 KMT2D TIMM50 MTREX CDC27 MGA PCCA CDC23

7.53e-0512941411630804502
Pubmed

Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.

NOC2L SPTAN1 BIRC6 TASOR2 DHX8 PDIA4 HELZ2 PYGB PYGL MTREX CNOT1

7.64e-056531411122586326
Pubmed

Fgf and Esrrb integrate epigenetic and transcriptional networks that regulate self-renewal of trophoblast stem cells.

AKAP8 CDKN2AIP INTS6 CDC27 MGA CDC23

8.86e-05177141626206133
Pubmed

Shotgun sequencing of the human transcriptome with ORF expressed sequence tags.

ACADSB NOC2L HNRNPL INTS6 FAT1 KMT2D TRANK1 LOXHD1 HELZ2 TNXB

9.02e-055521411010737800
Pubmed

Opposing gene regulatory programs governing myofiber development and maturation revealed at single nucleus resolution.

MYH4 MYH8 MYBPC2

9.49e-0522141337468485
Pubmed

A new role for the calcineurin/NFAT pathway in neonatal myosin heavy chain expression via the NFATc2/MyoD complex during mouse myogenesis.

MYH1 MYH4 MYH8

9.49e-0522141324301466
Pubmed

Crucial roles for interactions between MLL3/4 and INI1 in nuclear receptor transactivation.

KMT2C KMT2D

9.74e-054141219221051
Pubmed

Cancer gene mutation frequencies for the U.S. population.

KMT2C KMT2D

9.74e-054141234645806
Pubmed

Regulation of PTEN by Rho small GTPases.

PTEN ROCK1

9.74e-054141215793569
Pubmed

Evaluation of embryonic and perinatal myosin gene mutations and the etiology of congenital idiopathic clubfoot.

MYH1 MYH8

9.74e-054141220357587
Pubmed

Smooth muscle myosin light chain kinase expression in cardiac and skeletal muscle.

MYH1 MYH4

9.74e-054141211029314
Pubmed

Anaphase-promoting complex/cyclosome protein Cdc27 is a target for curcumin-induced cell cycle arrest and apoptosis.

CDC27 CDC23

9.74e-054141222280307
Pubmed

Modulation of skeletal muscle fiber type by mitogen-activated protein kinase signaling.

MYH1 MYH4

9.74e-054141218417546
Pubmed

Phosphatome profiling reveals PTPN2, PTPRJ and PTEN as potent negative regulators of PKB/Akt activation in Ras-mutated cancer cells.

PTEN PTPRJ

9.74e-054141219922411
Pubmed

Human MYO18B, a novel unconventional myosin heavy chain expressed in striated muscles moves into the myonuclei upon differentiation.

MYH1 MYH4

9.74e-054141212547197
Pubmed

MLL3/MLL4 are required for CBP/p300 binding on enhancers and super-enhancer formation in brown adipogenesis.

KMT2C KMT2D

9.74e-054141228398509
Pubmed

Comparative sequence analysis of the complete human sarcomeric myosin heavy chain family: implications for functional diversity.

MYH1 MYH4

9.74e-054141210388558
Pubmed

Behavioral abnormalities observed in Zfhx2-deficient mice.

ZFHX4 ZFHX3

9.74e-054141223300874
Pubmed

A human YAC transgene rescues craniofacial and neural tube development in PDGFRalpha knockout mice and uncovers a role for PDGFRalpha in prenatal lung growth.

MYH1 MYH4

9.74e-054141211023856
Pubmed

A subset of mixed lineage leukemia proteins has plant homeodomain (PHD)-mediated E3 ligase activity.

KMT2C KMT2D

9.74e-054141223129768
Pubmed

Aging-related dysregulation in enteric dopamine and angiotensin system interactions: implications for gastrointestinal dysfunction in the elderly.

DRD1 AGTR1

9.74e-054141229541380
Pubmed

The MLL3/MLL4 branches of the COMPASS family function as major histone H3K4 monomethylases at enhancers.

KMT2C KMT2D

9.74e-054141224081332
InteractionRSPH6A interactions

MYH1 MYH4 MYH8 PYGM MYBPC2

3.44e-06341395int:RSPH6A
InteractionTAFA5 interactions

FAT4 VWDE HNRNPL LNPEP

6.15e-06181394int:TAFA5
GeneFamilyGlycogen phosphorylases

PYGB PYGL PYGM

1.41e-073953437
GeneFamilyTetratricopeptide repeat domain containing|Bardet-Biedl syndrome associated|BBSome

RPAP3 TTC3 TTC6 TRANK1 CDC27 CDC23

3.18e-05115956769
GeneFamilyMyosin heavy chains

MYH1 MYH4 MYH8

6.11e-05159531098
GeneFamilyAnaphase promoting complex |Tetratricopeptide repeat domain containing

CDC27 CDC23

2.39e-0314952402
GeneFamilyZinc fingers C2H2-type|ZF class homeoboxes and pseudogenes

ZFHX4 ZFHX3

2.74e-0315952529
CoexpressionAtlasDevelopingGonad_e14.5_ epididymis_emap-29141_top-relative-expression-ranked_1000

MGAM GRIK1 HMMR PTEN FHIP2A BIRC6 ITIH5 DMXL1 KMT2C FARSA PKHD1 ROCK1 ZFHX3 LUM HERC1 MGA LRRC17

1.48e-0580113617gudmap_developingGonad_e14.5_ epididymis_1000
CoexpressionAtlasDevelopingGonad_e18.5_epididymis_emap-13166_top-relative-expression-ranked_1000

MGAM GRIK1 HMMR PTEN FHIP2A BIRC6 ITIH5 DMXL1 KMT2C PKHD1 ROCK1 LUM HERC1 MGA TNXB LRRC17

5.39e-0579913616gudmap_developingGonad_e18.5_epididymis_1000
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ Genital tubercle M_emap-6706_M-2fold-vs-F_top305_305

MYH8 CDKN2AIP ALG11 TTC3 LNPEP JAG1 UBA6 ROCK1 CDC27

5.56e-052661369gudmap_developingLowerUrinaryTract_e14.5_ Genital tubercle M_250_M-vs-F-2X
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYH1 MGAM FAT4 FAT1 TRANK1 LOXHD1 ZFHX4 PKHD1 ELAVL4 MYO15A

3.98e-10184141102cbed6462fea2622871bb7e49b0df3d984239281
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYH1 MGAM FAT4 FAT1 TRANK1 LOXHD1 ZFHX4 PKHD1 ELAVL4 MYO15A

3.98e-1018414110ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYH1 MGAM FAT4 FAT1 TRANK1 LOXHD1 ZFHX4 PKHD1 ELAVL4 MYO15A

3.98e-10184141102b19a8c5f823e00812908b23e66bb4e563278aff
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Lamp5-Lamp5_Ntn1_Npy2r|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

FAT4 VRK1 DRD1 TRPC4 DOCK10 GRIK1 FAT1 ZNF804B

3.05e-0815214188ff5a178a8f3550d89a003c0858820aab3773386
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Esm1|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

MYH1 MYH4 MYH8 CNTNAP3 GRIK1 SERPINA12 SNX31

2.06e-0713114173cb4b272e28ee9bad6d874f64a7aae18352a6cfb
ToppCellRA-01._Fibroblast_I|World / Chamber and Cluster_Paper

MYH4 ZNF708 ZNF804B ZFHX3 GNAO1 LUM MMP19

1.82e-0618114172b6ddeb53a79a658e2ba78527ff48c155b20daa6
ToppCellPosterior_cortex-Endothelial-ENDOTHELIAL_TIP-Dcn_1|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

KL SLC22A14 C6 LUM MMP19 TNXB

2.68e-06123141628be15b759c152662b29c323b1cc3f02f7830dbe
ToppCellPCW_13-14-Mesenchymal-Mesenchymal_fibroblastic-mes_immature5_(6)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

SCFD2 FAT4 DOCK10 ZFHX4 FARP1 LUM PCCA

2.89e-061941417b1bb0f846d2865efdd9bc8842b16b9d069785882
ToppCell10x3'2.3-week_17-19-Mesenchymal_fibro-stroma-arteriolar_fibroblast|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

FAT4 CRLF1 ZFHX4 AGTR1 LUM TNXB LRRC17

3.41e-06199141795d95e9b7bd3933188998ae94986213eb0f1e5ea
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Rxfp1_Eya1|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

CNTNAP3 GRIK1 SERPINA12 FAT1 SNX31

6.33e-0682141542017b8ace6f142a8358213c95a2632226c3a867
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

MYH1 MYH4 MYH8 FAT1 FARP1 HEPHL1

1.40e-051641416382e42701779d12a7948690b3be72d06dd75c8b4
ToppCelldroplet-Large_Intestine-COLON_PROXIMAL-30m-Epithelial-Lgr5+_amplifying_undifferentiated_cell|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

OGFRL1 CUL5 PYGB ZFHX3 MTREX PUS7L

1.60e-051681416d69452e2cfeb74023b5cf3d09064d7dcad0008ec
ToppCell5'-Adult-LargeIntestine-Mesenchymal-fibroblastic-Stromal_1_(ADAMDEC1+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FAT4 TRPC4 ITIH5 FARP1 LUM MMP19

1.66e-051691416c0824a93674e2bff0f09b2d2fab5bab016a2e379
ToppCellPCW_05-06-Neuronal-Neuronal_SCP-neuro_proliferating_SCP3_(1)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

RASGRF2 DOCK10 SHC4 SHD ELAVL4 PYGL

1.66e-051691416d9c3b22f62b882b8a2ea6fd9cf7afbe6d1775745
ToppCelldroplet-Limb_Muscle-Pre-Sort-18m-Mesenchymal-skeletal_muscle_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYH1 MYH4 NRAP MYLK2 PYGM MYBPC2

1.95e-0517414164a6e04b4f12b87c15fa1409989cbe32c43736369
ToppCellSevere-CD4+_T_activated|Severe / Disease group and Cell class

ADCY4 SAMD9 VWDE TRANK1 HELZ2 ELAVL4

2.15e-051771416a08f170f1143fcdd7d0842a54d9b807a4548f8b7
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

DOK6 TRPC4 PTEN ITIH5 JAG1 AGTR1

2.15e-051771416a8625d14682183cf77cb51eaf11bc15a3528f586
ToppCelldroplet-Limb_Muscle-nan-18m-Mesenchymal-skeletal_muscle_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYH1 MYH4 NRAP MYLK2 PYGM MYBPC2

2.15e-051771416f6ff1b035fa2418f2448c99d81faa927ece93dfa
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

DOK6 TRPC4 PTEN ITIH5 JAG1 AGTR1

2.15e-0517714163645e2f4a48283f290f85c49c3e79e3f58ac9aa6
ToppCellSevere-CD4+_T_activated|World / Disease group and Cell class

ADCY4 SAMD9 VWDE TRANK1 HELZ2 ELAVL4

2.22e-051781416ef6111238703579a34bd6948bd9d4ca6b7e16063
ToppCelldroplet-Limb_Muscle-MUSCLE-1m-Mesenchymal-skeletal_muscle_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYH1 MYH4 NRAP MYLK2 PYGM MYBPC2

2.22e-05178141669f68eeab11b088fcb1f963c92eff0f1cd0e711a
ToppCellPCW_05-06-Neuronal-Neuronal_SCP|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

RASGRF2 DOCK10 SHC4 SHD PTPRJ ELAVL4

2.52e-051821416b4fc5e4f5d8440a3c9ee0a6fd0da87b43cabc8c6
ToppCelldroplet-Limb_Muscle-nan-3m-Mesenchymal-skeletal_muscle_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYH1 MYH4 NRAP MYLK2 PYGM MYBPC2

2.52e-051821416edfc598b7199ca1d8a399b264ab863c299b1eede
ToppCellPCW_05-06-Neuronal-Neuronal_SCP-neuro_SCP_(0)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

RASGRF2 DOCK10 SHC4 SHD PTPRJ ELAVL4

2.59e-051831416f517215ff45dec914af52dfdbc4579c19654c3aa
ToppCellPCW_05-06-Neuronal-Neuronal_SCP-neuro_proliferating_SCP1_(1)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

RASGRF2 DOCK10 SHC4 SHD PTPRJ ELAVL4

2.76e-051851416a8946379fc066903fe8f4bc9cbf693b7b424a0cd
ToppCelldroplet-Limb_Muscle-nan-24m-Mesenchymal-skeletal_muscle_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYH1 MYH4 NRAP MYLK2 PYGM MYBPC2

2.76e-0518514169245c322aae8bb9065d50dada198a5ee143a3444
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

DOK6 PRICKLE1 FAT1 FARP1 ZNF804B PKHD1

2.84e-051861416f28d72b47624b69a580b4429e2be560a26898591
ToppCellPCW_05-06-Neuronal|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

RASGRF2 DOCK10 SHC4 VWDE SHD ELAVL4

2.93e-05187141603a2ed85b171c887d4f3b0f4fe2e1cb4a853e658
ToppCellhuman_hepatoblastoma-Tumor_cells-T2|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)

SCFD2 ACADSB RASGRF2 TTC6 FARP1 PKHD1

2.93e-051871416f3e37c18ac6471c7992609bbddfa4975571c815c
ToppCell10x5'-GI_small-bowel-Lymphocytic_T_CD4-T_CD4/CD8|GI_small-bowel / Manually curated celltypes from each tissue

DOCK10 BIRC6 TASOR2 KMT2C LNPEP HERC1

3.02e-051881416ab9b725d6e0cdab8e9ddda6dee09e14730e9a578
ToppCell(2)_Fibroblasts-(20)_Fibro-1|World / Cell class and subclass of bone marrow stroma cells in homeostatis

CRLF1 ITIH5 LUM MMP19 TNXB LRRC17

3.02e-051881416409a7b69d02e87084ca955e3fe6c77230dee8861
ToppCellPBMC-Severe-Myeloid-Neutrophil-immature_Neutrophil-Neu_2|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

MGAM MMP27 RTN3 PFKFB2 OR6N1 PYGL

3.11e-0518914163b35022c0619df6db234613aa53a076899ca9562
ToppCellPBMC-Severe-Myeloid-Neutrophil-immature_Neutrophil-Neu_2|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

MGAM MMP27 RTN3 PFKFB2 OR6N1 PYGL

3.11e-051891416358ff514f1c8aa46067208ddf1b68396d789c130
ToppCelldroplet-Limb_Muscle-MUSCLE-30m-Mesenchymal-skeletal_muscle_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYH1 MYH4 NRAP MYLK2 PYGM MYBPC2

3.11e-051891416d2b008f98739c6af7ee63b643011a240db20e4d8
ToppCellCOVID-19-Heart-EC_+_Pericyte|Heart / Disease (COVID-19 only), tissue and cell type

ADCY4 RASGRF2 TRPC4 PTEN JAG1 ZFHX3

3.20e-051901416a21653bfb7bafbc273f94fa7c13bfb48cf8fd562
ToppCelldroplet-Limb_Muscle-MUSCLE-30m-Mesenchymal-unknown|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYH1 MYH4 NRAP MYLK2 PYGM MYBPC2

3.30e-051911416f932980baa032748857cb367a55c37dd975c693e
ToppCellfacs-Pancreas-Exocrine-3m-Mesenchymal-pancreatic_stellate_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ITIH5 PYGM LUM MMP19 TNXB LRRC17

3.39e-0519214168937a59f6bbe07f671bdabbd3707dc9c17a14cd9
ToppCellfacs-Pancreas-Exocrine-3m-Mesenchymal|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ITIH5 PYGM LUM MMP19 TNXB LRRC17

3.39e-051921416e4a7f2673f801b008ca67291db2fb2b9fd2955b8
ToppCellfacs-Pancreas-Exocrine-3m-Mesenchymal-pancreatic_stellate_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ITIH5 PYGM LUM MMP19 TNXB LRRC17

3.39e-051921416ac1477433704573f95111eee6263b93668d2845e
ToppCelldroplet-Lung-18m-Hematologic-myeloid-non-classical_monocyte-nonclassical_monocyte_l14|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

RPAP3 PFKFB2 PTPRJ JAG1 TNXB

3.41e-051161415f2bf9599040f43b5ea8724841d7b71c0a859c016
ToppCelldroplet-Fat-Scat-18m-Mesenchymal-Cd34+|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZFHX4 LUM MMP19 TNXB LRRC17 CRTAP

3.49e-051931416316ebdf15f75d88c348f909b643fcd315364ca84
ToppCelldroplet-Fat-Scat-18m-Mesenchymal-mesenchymal_stem_cell_of_adipose|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZFHX4 LUM MMP19 TNXB LRRC17 CRTAP

3.49e-0519314161afdd3f7d703f4204a2cbfe40e135ac7b09213f7
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

FAT1 PTPRJ FARP1 KCNJ16 PKHD1 PCCA

3.49e-0519314163866667dd221612589ae50f5c52f73a183a49ce6
ToppCelldroplet-Fat-Scat-18m-Mesenchymal|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZFHX4 LUM MMP19 TNXB LRRC17 CRTAP

3.49e-0519314168dc6db335678f3a5cfd36026ad811fed8d9cb4bc
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

TRPC4 PTEN JAK3 TRANK1 LUM TNXB

3.60e-05194141681713e0409e8be695ba5dfdc67a997b33435dd9e
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

FAT1 PTPRJ FARP1 KCNJ16 PKHD1 PCCA

3.60e-0519414167002937e8903e037332a215d00fbc7c7843b33f2
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

TRPC4 PTEN JAK3 TRANK1 LUM TNXB

3.60e-051941416627cffe2d448e74fc5df92e74e5b922a73304137
ToppCellfacs-GAT-Fat-3m-Mesenchymal-mesenchymal_progenitor|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ITIH5 LUM MMP19 TNXB LRRC17 CRTAP

3.70e-05195141669a29d03e664b72f32d41876510c62345c3aed31
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

TRPC4 PTEN LOXHD1 ZFHX4 AGTR1 LUM

3.70e-051951416cad6563cc51d212554152c727fc2c249c6a07e4d
ToppCellPCW_10-12-Mesenchymal-Mesenchymal_fibroblastic-mes_immature5_(6)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

FAT4 DOCK10 ZFHX4 FARP1 LUM PCCA

3.70e-0519514160e55fa5b3cbeb7baee3d4ac272a3bf80381ec937
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

TRPC4 PTEN LOXHD1 ZFHX4 AGTR1 LUM

3.70e-051951416783bfa8110161cbd6def50ce849cae676c39c458
ToppCellfacs-GAT-Fat-3m-Mesenchymal|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ITIH5 LUM MMP19 TNXB LRRC17 CRTAP

3.70e-0519514161cffae2b08dbfa1c633ce24023e89b66d28b5431
ToppCellfacs-GAT-Fat-3m-Mesenchymal-mesenchymal_stem_cell_of_adipose|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ITIH5 LUM MMP19 TNXB LRRC17 CRTAP

3.70e-0519514169cef6f18664518060af7c192310dddce6d70345a
ToppCellPBMC-Control-Lymphocyte-T/NK-NK_cell-NK_activated|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

MYH1 ADCY4 MYH8 TRANK1 CYP4X1

3.71e-0511814155f72022f4be3fb7ccec86dc05d37572833028886
ToppCellPBMC-Control-Lymphocyte-T/NK-NK_cell-NK_activated-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

MYH1 ADCY4 MYH8 TRANK1 CYP4X1

3.71e-051181415053c0986051e36fdc4c48b8067c137b6299b2f1b
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

FAT4 PRICKLE1 TRPC4 LOXHD1 AGTR1 LUM

3.81e-051961416a12dd986df65c36f248cf10815c3b8b6238613b0
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

FAT4 PRICKLE1 TRPC4 LOXHD1 AGTR1 LUM

3.81e-0519614163e6803587d8566fd08cb8b290be3b6461743d79c
ToppCellmild-Myeloid-Neutrophils_2|mild / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

MGAM SAMD9 RTN3 PTEN HELZ2 PYGL

3.81e-051961416e9f30eb8a3915c3b2af009c832bff9b349b65ae5
ToppCellControl-Lymphoid_T/NK-NK_activated|Control / Disease group, lineage and cell class

MYH1 ADCY4 MYH8 TRANK1 CYP4X1

3.86e-051191415a258d91ac90d4174b6f203d7f96ba6e57c6003e7
ToppCellPBMC-Control-Lymphocyte-T/NK-NK_cell-NK_activated|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

MYH1 ADCY4 MYH8 TRANK1 CYP4X1

3.86e-05119141528d6b0e9dda2fe4ca94ae9b95b7261618d0d9877
ToppCellPBMC-Control-Lymphocyte-T/NK-NK_cell-NK_activated-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

MYH1 ADCY4 MYH8 TRANK1 CYP4X1

3.86e-0511914150fdd5b093ac20a4bda0f7b623808eb3ad0bf68e2
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

TRPC4 PTEN ZFHX4 AGTR1 LUM TNXB

3.92e-051971416ae0435f4b4a9cdedb1c201fc56921048390097bf
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

TRPC4 PTEN ZFHX4 AGTR1 LUM TNXB

3.92e-05197141637f6b6f2809b952382eaebb642b0aad6371f4251
ToppCellPCW_10-12-Mesenchymal-Mesenchymal_fibroblastic-mes_immature1_(0)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

DOK6 FAT4 DOCK10 ITIH5 LUM LRRC17

3.92e-05197141611a4c417f035e554431a8f03be13b5eefa3530c0
ToppCell5'-Adult-SmallIntestine-Mesenchymal-fibroblastic-Stromal_1_(CCL11+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FAT4 ITIH5 FARP1 LUM MMP19 TNXB

4.03e-0519814167582ee9ec8a87ecb094201f1f9191b412f9d2875
ToppCellControl-Control-Lymphocyte-T/NK-CD4+_T_activated|Control / Disease, condition lineage and cell class

SAMD9 RASGRF2 CNTNAP3 TRANK1 HELZ2 LRRC17

4.03e-051981416ee71543559836fd59adc0da877b2ca538cba60cb
ToppCellsevere-Myeloid-Neutrophils_4|Myeloid / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

MGAM RTN3 PFKFB2 AHSP JAK3 PYGL

4.14e-05199141650242666def13e5d4149c563ae000d6768f086f7
ToppCellTracheal-NucSeq|Tracheal / Cell types per location group and 10X technology with lineage, and cell group designations

BIRC6 PACS1 KMT2C PTPRJ HERC1 PCCA

4.14e-05199141694b94b17ca18b8dc27b91da1f2ccf89e03cc7035
ToppCellControl_saline-Hematopoietic_Myeloid-Granulocytic_cells-Neutrophils|Control_saline / Treatment groups by lineage, cell group, cell type

MGAM SAMD9 PTPRJ PYGL PYGM LONRF3

4.14e-051991416e1240bfcdce76ec018599c50350748f9c7b8fb0e
ToppCellBronchus_Control_(B.)-Stromal-TX-Fibroblasts-2,_SCARA5|Bronchus_Control_(B.) / Sample group, Lineage and Cell type

FAT4 ZFHX4 AGTR1 LUM TNXB LRRC17

4.26e-0520014162022df85df94ab8cbb4e80e3fe9894c01051c5e0
ToppCell10x3'2.3-week_12-13-Mesenchymal_fibro-stroma-arteriolar_fibroblast|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

FAT4 ZFHX4 AGTR1 LUM TNXB LRRC17

4.26e-052001416fee22a6a6c7b93af204b5b56f2c34f1411500e18
ToppCellTracheal-10x5prime-Stromal-Fibroblastic-Fibro_peribronchial|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

FAT4 ITIH5 GNAO1 LUM MMP19 TNXB

4.26e-0520014168ab0051544ea32eb8b3f7f8ba7582deaf8bf26c0
ToppCellmild|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

SAMD9 BIRC6 HNRNPL KMT2C HELZ2 ROCK1

4.26e-05200141612f1685ce8f218433068e090c9d839cd5a1910bf
ToppCellFrontal_cortex-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Sst-Inhibitory_Neuron.Gad1Gad2.Sst-Nr2f2_(MGE-derived_cortical_interneurons--Martinotti_cells)|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

MYH1 MYH4 MYH8 VWDE

4.48e-05621414a20620a8869721ea62984c2022ee1b484b455824
ToppCellFrontal_cortex-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Sst-Inhibitory_Neuron.Gad1Gad2.Sst-Nr2f2_(MGE-derived_cortical_interneurons--Martinotti_cells)-|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

MYH1 MYH4 MYH8 VWDE

4.48e-05621414ee694c06bcd924b4ddf744178ba3a99e04eed51b
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Chrna2_Ptgdr|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

MYH1 MYH4 MYH8 CNTNAP3 SERPINA12

4.88e-051251415d05556ea185c15815a4f8643f1c01185badbeece
ToppCellHippocampus-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)-Slc17a6-Excitatory_Neuron.Slc17a6.Grp_(Neuron.Slc17a6.Grp)-|Hippocampus / BrainAtlas - Mouse McCarroll V32

MYH1 MYH8 GSTA2 PKHD1

5.39e-05651414b7bc23af54d6d2f7afd584f4df42c24d7c49e344
ToppCellHippocampus-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)-Slc17a6-Excitatory_Neuron.Slc17a6.Grp_(Neuron.Slc17a6.Grp)|Hippocampus / BrainAtlas - Mouse McCarroll V32

MYH1 MYH8 GSTA2 PKHD1

5.39e-056514143b3630253f5713c4a688c74c4ea0f98c1fe42594
ToppCellFrontal_cortex-Endothelial-ENDOTHELIAL_TIP-Dcn_1-Dcn_1_1|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

MMP27 KL LUM MMP19 TNXB

5.67e-051291415856255fbfc7f95642000cfd7704141b2388f7c5c
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Tac2_Myh4|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

MYH1 MYH4 MYH8 CNTNAP3 SERPINA12

5.67e-051291415f83187c0bb06528127b8d2d56674ab1946846951
ToppCellSubstantia_nigra-Endothelial-ENDOTHELIAL_TIP-Dcn_1|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

SERPINA11 C6 LUM MMP19 TNXB

6.33e-051321415893b7ec2a2d8a140cc98575d1beca1189f053e9a
ToppCellNS-moderate-d_07-13-Epithelial-Basal|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

FAT4 DAPL1 PPA1 VWDE

6.82e-05691414c2d7333a9d7c7e1cdc36d28192ddb6afa2013816
ToppCellhealthy_donor-Lymphocytic-T_cell-CD4+_T_cell_(ISG_high)|healthy_donor / Disease condition, Lineage, Cell class and subclass

SAMD9 RASGRF2 CUL5 HELZ2 C6

7.81e-05138141597f5dc17522462133e582b508ad0ef036e656872
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Pvalb-Pvalb_Gabrg1|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

TRPC4 GRIK1 ZNF804B SNX31 PYGM

8.36e-0514014152c44e8cc5190226049be7ebc465d685393e701c4
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Crispld2_Htr2c|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

CRLF1 DOCK10 SERPINA12 ITIH5 PYGM

1.02e-04146141547368f981180ca6a8c81a50f7f9430f12456f609
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Chrna2_Glra3|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

MYH1 MYH4 MYH8 CRLF1 CNTNAP3

1.05e-04147141550e86860a94be103092c40e39a172eac92372f0d
ToppCellThalamus-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)-Slc17a7-Tac2-Excitatory_Neuron.Slc17a7.Tac2.Wif1_(Medial_habenular,_lateral_portion)|Thalamus / BrainAtlas - Mouse McCarroll V32

MYH1 POU4F3 VWDE MYBPC2

1.22e-04801414da18df34b4f630fe4fe3110e3c3c3602aef92aab
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Lamp5-Lamp5_Plch2_Dock5|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

VRK1 DOCK10 GRIK1 FAT1 AGTR1

1.23e-041521415fed80b467ec9e30c7f98bed6cc4f8c583b715e9e
ToppCellPND07-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_T-CD4_T-CD4_T_prolif|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CASP8AP2 DAPL1 SMYD4 KL CYP4X1

1.27e-0415314150ad401cb70b9edfc6ae6ccba6879c6c2b6c4d296
ToppCell10x5'-Lung-Lymphocytic_T_CD4-T_CD4/CD8|Lung / Manually curated celltypes from each tissue

WDR93 JAK3 KCNJ16 CYP4X1 C6

1.39e-04156141510d191e29b16cae8238e8df6c0ff38882253f34e
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Myh8_Fibin|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

MYH1 MYH4 MYH8 CNTNAP3 GRIK1

1.43e-041571415741d79c10cb87fa7f14080c6fccb1553c3a20bad
ToppCellHippocampus-Endothelial-ENDOTHELIAL_TIP-Dcn_1|Hippocampus / BrainAtlas - Mouse McCarroll V32

ITIH5 LUM MMP19 PCCA TNXB

1.52e-04159141592049a8d8fc9997d8d0d76500c72596a9b2394e0
ToppCellfacs-Lung-nan-3m-Endothelial-Capillary_Type_1_Cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYH1 NRAP SHC4 ELAVL4 NMS

1.56e-041601415f2cdee5a9e3b0eb125d6be7b5d239eb04333ae41
ToppCellTransplant_Alveoli_and_parenchyma-Epithelial-Ciliated_2|Epithelial / Tissue, Lineage and Cell class of Lung Cells from 10X

DNHD1 ALG11 GSTA2 TBC1D32 CCDC15

1.56e-0416014156de505bfe1fbbe984718740a9cf43d0e02ff452e
ToppCellBronchial-NucSeq-Endothelial-Endothelia_vascular-VE_systemic_arterial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

ADCY4 PDE6C RASGRF2 GAREM2 ZNF804B

1.76e-0416414153cd80e6275f0f9b5667912139d15ebf5e6b17f2f
ToppCell5'-GW_trimst-2-SmallIntestine-Mesenchymal-immature_mesenchymal_cell-Mesoderm_1_(HAND1+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MMP27 GDPD4 SERPINA11 UBE2T LUM

1.76e-04164141572ef807895385ba23e30d19d12b1b0549a699690
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Crispld2_Htr2c|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

CRLF1 DOCK10 SERPINA12 ITIH5 PYGM

1.81e-041651415c6b23013d77fa9aa967b76e451c8e42b0a657c30
ToppCellfacs-Heart-RV-24m-Mesenchymal-fibroblast_of_cardiac_tissue|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SERPINA12 GDPD4 SERPINA11 LUM TNXB

1.91e-0416714153e3d8f6df2feefafad5b44ba0ebf5b5a0fe4ed58
ToppCellfacs-Heart-RV-24m-Mesenchymal-fibroblast_of_cardiac_tissue|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SERPINA12 GDPD4 SERPINA11 LUM TNXB

1.91e-0416714153ad9f3122dbe96580f640388ef920ea209fc2349
ToppCellfacs-Trachea-3m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l44-58|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

MYH1 MYH4 MYH8 NRAP MYBPC2

1.91e-041671415d78356bf0c473816dbabaee51984940bd822f84e
Drugmono-(2-ethylhexyl)phthalate

ADCY4 MYH8 PDE6C NRAP RASGRF2 DOCK10 PEX1 GDPD4 PACS1 FAT1 KL LNPEP AGTR1 KCNJ16 PKHD1 MYO15A MMP19 TNXB MYBPC2

2.31e-0865814019ctd:C016599
DrugB0683

MYH1 MYH4 MYH8 ARPC3 MYLK2 ROCK1 MYO15A MYL12B MYBPC2

4.56e-081171409CID006398969
Drugheptenitol

MGAM PYGB PYGL PYGM

4.72e-0871404CID000188267
Drug3,5-dimethylphenyl isocyanate

PYGB PYGL PYGM

2.28e-0731403CID000521488
Drug5'-deoxy-5'-fluoro-5'-(methylthio)adenosine

PYGB PYGL PYGM

2.28e-0731403CID000147839
DrugNSC758405

PYGB PYGL PYGM

2.28e-0731403CID000003201
Drug3,5-dinitrophenyl phosphate

PYGB PYGL PYGM

2.28e-0731403CID000151920
Drugpyridoxal phosphoglucose

PYGB PYGL PYGM

2.28e-0731403CID000196007
Drug5-ethyl-4-hydroxy-2-methyl-3(2H)-furanone

PYGB PYGL PYGM

2.28e-0731403CID000093111
Drugadenosine-5'-chloromethylphosphonate

PYGB PYGL PYGM

2.28e-0731403CID000191554
Drughydan

PYGB PYGL PYGM

2.28e-0731403CID000008360
DrugEHMF

PYGB PYGL PYGM

2.28e-0731403CID000033931
Drugpyridoxal 5'-methylenephosphonate

PYGB PYGL PYGM

2.28e-0731403CID003082249
DrugPlp 5'-mpa

PYGB PYGL PYGM

2.28e-0731403CID003082151
Drugglucose-1,2-cyclic phosphate

PYGB PYGL PYGM

2.28e-0731403CID000191723
Drug3'-FFdUrd

PYGB PYGL PYGM

2.28e-0731403CID000072260
Drug2',3',4',5,5'-pentachloro-2-biphenylol

PYGB PYGL PYGM

2.28e-0731403CID000119518
DrugAC1L8XK3

PYGB PYGL PYGM

2.28e-0731403CID000409735
DrugN-acetyl-N'-beta-D-glucopyranosyl urea

PYGB PYGL PYGM

2.28e-0731403CID000446801
Drugriboflavin tetraacetate

PYGB PYGL PYGM

2.28e-0731403CID000094186
Drug2,5-dimethyl-3-furanone

PYGB PYGL PYGM

2.28e-0731403CID000085730
Drug3,5-dinitrophenol

PYGB PYGL PYGM

2.28e-0731403CID000011459
Drugglucosyl fluoride

MGAM PYGB PYGL PYGM

4.37e-07111404CID000150967
Drug9 Da

MGAM PYGB PYGL PYGM

4.37e-07111404CID005287565
Drugeye gene

MYH1 MYH4 ADCY4 MYH8 DRD1 MYLK2 AGTR1 PYGB PYGL ROCK1 PYGM MYO15A MYL12B

4.85e-0736914013CID000004782
Drugformycin triphosphate

MYH1 MGAM MYH4 MYH8 MYO15A MYL12B

6.96e-07511406CID000122274
Druggalocitabine

PYGB PYGL PYGM

9.06e-0741403CID000065950
Drug5-deoxyribose-1-phosphate

PYGB PYGL PYGM

9.06e-0741403CID000135786
Drugingliforib

PYGB PYGL PYGM

9.06e-0741403CID006451325
Druguric acid riboside

PYGB PYGL PYGM

9.06e-0741403CID000164933
Drugpseudo-dl-glucose

PYGB PYGL PYGM

9.06e-0741403CID000125259
Drugpyridoxal diphosphate

PYGB PYGL PYGM

9.06e-0741403CID000125696
Drug2,5-anhydro-D-mannitol 1-phosphate

PYGB PYGL PYGM

9.06e-0741403CID000189134
DrugAC1LAMW2

PYGB PYGL PYGM

9.06e-0741403CID000491364
DrugFdUrd-C8

PYGB PYGL PYGM

9.06e-0741403CID000094262
DrugMem-CC

PYGB PYGL PYGM

9.06e-0741403CID003081269
DrugBCIp4A

PYGB PYGL PYGM

9.06e-0741403CID000192417
Drug3'-chloromethotrexate

PYGB PYGL PYGM

9.06e-0741403CID000097703
Drugpurealin

MYH1 MGAM MYH4 MYH8 MYO15A MYL12B

1.51e-06581406CID006419303
Drug4-nitrophenylmaltoheptaoside

MGAM PYGB PYGL PYGM

1.77e-06151404CID000173254
Drugquin2

ADCY4 MYLK2 PDIA4 PYGB PYGL PYGM MYL12B

2.01e-06951407CID000104841
Drugheptulose-2-P

PYGB PYGL PYGM

2.26e-0651403CID000124823
Drug6-FPLP

PYGB PYGL PYGM

2.26e-0651403CID000146246
Druggluconohydroximo-1,5-lactone

PYGB PYGL PYGM

2.26e-0651403CID009576855
DrugDHPBU

PYGB PYGL PYGM

2.26e-0651403CID000125914
Drug5'-isobutylthioinosine

PYGB PYGL PYGM

2.26e-0651403CID003080910
Drugindirubin-5-sulphonate

PYGB PYGL PYGM

2.26e-0651403CID005288641
DrugAC1LCUXJ

PYGB PYGL PYGM

2.26e-0651403CID000656425
Drug6-amino-5-bromouracil

PYGB PYGL PYGM

2.26e-0651403CID000080578
Drugetafenone

PYGB PYGL PYGM

2.26e-0651403CID000003275
DrugddEtUrd

PYGB PYGL PYGM

2.26e-0651403CID000451452
Drug5-trifluoromethyl-2'-deoxycytidine

PYGB PYGL PYGM

2.26e-0651403CID000125618
Drugm-anisidine

PYGB PYGL PYGM

2.26e-0651403CID000010824
Drug2-hydroxypropylphosphonate

PYGB PYGL PYGM

2.26e-0651403CID000441028
Drug6-FDPL

PYGB PYGL PYGM

2.26e-0651403CID000129578
Drug3'-O-methylpyridoxal 5'-phosphate

PYGB PYGL PYGM

2.26e-0651403CID003082179
DrugGlcMan

PYGB PYGL PYGM

2.26e-0651403CID000152120
DrugU66985

PYGB PYGL PYGM

2.26e-0651403CID000127224
DrugAC1O3M08

PYGB PYGL PYGM

2.26e-0651403CID006331955
Drugbutylethanolamine

MGAM PYGB PYGL PYGM

2.35e-06161404CID000249006
DrugAC1L1IZ2

MYH1 MGAM MYH4 ADCY4 MYH8 ARPC3 MYLK2 SHD ROCK1 MYO15A MYL12B

2.96e-0630414011CID000004795
Drughomonojirimycin

MGAM PYGB PYGL PYGM

3.06e-06171404CID000159496
Drugfagomine

MGAM PYGB PYGL PYGM

3.06e-06171404CID000072259
DrugCV-araU

PYGB PYGL PYGM

4.49e-0661403CID006441877
Drug2-thiothymidine

PYGB PYGL PYGM

4.49e-0661403CID003005944
DrugCarbocyclic Bvdc

PYGB PYGL PYGM

4.49e-0661403CID006438602
Drug2,2-dimethyl-3-hydroxybutyric acid

PYGB PYGL PYGM

4.49e-0661403CID000152984
DrugEdUMP

PYGB PYGL PYGM

4.49e-0661403CID003085112
Drug4-hydroxyacetophenone

GSTA2 PYGL PYGM

4.49e-0661403ctd:C031335
Drug5'-deoxy-5'-chloroformycin

PYGB PYGL PYGM

4.49e-0661403CID000126430
Drug5-n-propylthioadenosine

PYGB PYGL PYGM

4.49e-0661403CID000656428
DrugAzddCyd

PYGB PYGL PYGM

4.49e-0661403CID000451374
Drug5-Ffdru

PYGB PYGL PYGM

4.49e-0661403CID000065561
DrugCarbocyclic Ivdu

PYGB PYGL PYGM

4.49e-0661403CID006439191
DrugDNPP

PYGB PYGL PYGM

4.49e-0661403CID000067056
Drug5-chloro-indole-2-carboxylic acid

PYGB PYGL PYGM

4.49e-0661403CID000082693
DrugNSC-97433

PYGB PYGL PYGM

4.49e-0661403CID000001803
DrugAR-L57

PYGB PYGL PYGM

4.49e-0661403CID000156890
Drugartemether

PYGB PYGL PYGM C6

6.15e-06201404CID000068911
DrugAC1L3XPY

MGAM PYGB PYGL PYGM

7.56e-06211404CID000124005
DrugI0329

MGAM PYGB PYGL PYGM

7.56e-06211404CID000439668
Drugblebbistatin

MYH1 MYH4 MYH8 MYLK2 ROCK1 MYO15A MYL12B

7.63e-061161407CID003476986
Drugalpha-(fluoromethyl)dehydroornithine

PYGB PYGL PYGM

7.82e-0671403CID006439607
Drug6-fluoropyridoxal

PYGB PYGL PYGM

7.82e-0671403CID003080803
DrugAC1L3372

PYGB PYGL PYGM

7.82e-0671403CID000108025
Drug1 Gpt

PYGB PYGL PYGM

7.82e-0671403CID000101247
Drugformycins

PYGB PYGL PYGM

7.82e-0671403CID000512867
Drug5'-methylthioinosine

PYGB PYGL PYGM

7.82e-0671403CID000161214
Drughydantocidin

PYGB PYGL PYGM

7.82e-0671403CID000125429
Drug2',3'-dideoxy-3'-fluorocytidine

PYGB PYGL PYGM

7.82e-0671403CID000356019
DrugPromonta

PYGB PYGL PYGM

7.82e-0671403CID000108494
Drugmaltosaccharide

MGAM PYGB PYGL PYGM

9.19e-06221404CID005461034
DrugAC1Q6SL6

MGAM PPA1 PYGB PYGL PYGM

1.02e-05471405CID000000198
Drugginsenoside

MGAM PYGB PYGL PYGM

1.11e-05231404CID000092797
DrugNSC611747

MYH1 MYH4 MYH8 TRPC4 PPA1 MYLK2 PYGB PYGL ROCK1 MYO15A MYL12B

1.18e-0535214011CID000002534
Drug6-methylpurine

PYGB PYGL PYGM

1.25e-0581403CID005287547
DrugEtafenone [inn]

PYGB PYGL PYGM

1.25e-0581403CID000066659
DrugAC1NUVX5

PYGB PYGL PYGM

1.25e-0581403CID005461894
Drugamorphin

PYGB PYGL PYGM

1.25e-0581403CID000122792
Drug1,2-dideoxy-d-arabino-hex-1-enopyranose

MGAM PYGB PYGL PYGM

1.57e-05251404CID000089465
DiseaseAdenoid Cystic Carcinoma

PTEN KMT2C FAT1 JAG1 PYGB MGA

8.13e-061001396C0010606
Diseaseautosomal dominant hyaline body myopathy (implicated_via_orthology)

MYH1 MYH4 MYH8

1.20e-05101393DOID:0111269 (implicated_via_orthology)
Diseasedistal arthrogryposis type 2B3 (implicated_via_orthology)

MYH1 MYH4 MYH8

1.20e-05101393DOID:0111602 (implicated_via_orthology)
Diseasedistal arthrogryposis type 1 (implicated_via_orthology)

MYH1 MYH4 MYH8

1.20e-05101393DOID:0111596 (implicated_via_orthology)
Diseasedilated cardiomyopathy 1S (implicated_via_orthology)

MYH1 MYH4 MYH8

1.20e-05101393DOID:0110454 (implicated_via_orthology)
Diseasecongenital myopathy 6 (implicated_via_orthology)

MYH1 MYH4 MYH8

1.20e-05101393DOID:0080719 (implicated_via_orthology)
Diseaseinclusion body myositis (implicated_via_orthology)

MYH1 MYH4 MYH8

1.20e-05101393DOID:3429 (implicated_via_orthology)
Diseasedistal arthrogryposis type 2A (implicated_via_orthology)

MYH1 MYH4 MYH8

1.20e-05101393DOID:0111605 (implicated_via_orthology)
Diseasefamilial hypertrophic cardiomyopathy (implicated_via_orthology)

MYH1 MYH4 MYH8

1.20e-05101393DOID:0080326 (implicated_via_orthology)
DiseaseMalignant neoplasm of breast

MYH1 AKAP8 RASGRF2 SPTAN1 TRPC4 PPA1 HMMR PTEN TTC3 HNRNPL CUL5 KMT2D RPRD1A FARP1 JAG1 LONRF3 CDC27

1.28e-05107413917C0006142
Diseasedistal myopathy (implicated_via_orthology)

MYH1 MYH4 MYH8

2.18e-05121393DOID:11720 (implicated_via_orthology)
Diseasemyotonia congenita (implicated_via_orthology)

MYH1 MYH4 MYH8

2.18e-05121393DOID:2106 (implicated_via_orthology)
DiseaseKleefstra syndrome 2 (implicated_via_orthology)

KMT2C KMT2D

2.20e-0521392DOID:0080598 (implicated_via_orthology)
Diseaserestrictive cardiomyopathy (implicated_via_orthology)

MYH1 MYH4 MYH8

2.83e-05131393DOID:397 (implicated_via_orthology)
Diseasedilated cardiomyopathy (implicated_via_orthology)

MYH1 MYH4 MYH8 JAG1 AGTR1

3.91e-05801395DOID:12930 (implicated_via_orthology)
Diseasedistal arthrogryposis (implicated_via_orthology)

MYH1 MYH4 MYH8

4.47e-05151393DOID:0050646 (implicated_via_orthology)
Diseasemyopathy (implicated_via_orthology)

MYH1 MYH4 MYH8 MYBPC2

7.81e-05481394DOID:423 (implicated_via_orthology)
DiseaseSquamous cell carcinoma of esophagus

FAT4 KMT2C FAT1 KMT2D TNXB

8.90e-05951395C0279626
DiseaseSezary Syndrome

PTEN KMT2C KMT2D

2.75e-04271393C0036920
Diseasecongenital heart disease (implicated_via_orthology)

SMYD4 KMT2C KMT2D MYBPC2

3.22e-04691394DOID:1682 (implicated_via_orthology)
Diseasetea consumption measurement

MGAM VRK1 PKHD1 ELAVL4 ZFHX3

3.72e-041291395EFO_0010091
DiseaseNAD-dependent protein deacetylase sirtuin-2 measurement

C3orf22 ITIH5

4.56e-0471392EFO_0008241
Diseaselung non-small cell carcinoma (is_implicated_in)

PTEN KMT2C FAT1 KMT2D ZFHX3

5.23e-041391395DOID:3908 (is_implicated_in)
Diseasekallistatin measurement

SERPINA12 SERPINA11

6.06e-0481392EFO_0008196
Diseasetyrosine-protein kinase receptor TYRO3 measurement

MGAM MGA

6.06e-0481392EFO_0020829
Diseasegdnf family receptor alpha-1 measurement

GNAO1 TNXB

6.06e-0481392EFO_0020400
Diseaseperiodontitis

ACADSB GRIK1 PTEN TTC6 KCNJ16 ZFHX3

6.79e-042231396EFO_0000649
DiseaseMalignant tumor of prostate

PTEN ZFHX3

7.76e-0491392cv:C0376358
Diseaseresponse to glucocorticoid, osteonecrosis

GRIK1 NARF ZFHX3

8.26e-04391393EFO_0004259, GO_0051384
Diseasepolybrominated biphenyl measurement, gestational serum measurement, fetal genotype effect measurement, polybrominated diphenyl ether measurement

LOXHD1 ZFHX3

1.18e-03111392EFO_0007959, EFO_0007961, EFO_0007962, EFO_0007964
DiseasecAMP-specific 3',5'-cyclic phosphodiesterase 4D measurement

GNAO1 TNXB

1.18e-03111392EFO_0020224
Diseasesmoking behavior

NRAP RASGRF2 DOCK10 PKHD1 ELAVL4 ZFHX3 PCCA

1.20e-033411397EFO_0004318
Diseaseesophagus squamous cell carcinoma (is_implicated_in)

KMT2C FAT1 KMT2D

1.26e-03451393DOID:3748 (is_implicated_in)
DiseaseMalignant neoplasm of salivary gland

FAT1 JAG1 PYGB

1.26e-03451393C0220636
DiseaseBell's palsy

MGAM POU4F3 FARP1 MGA

1.40e-031021394EFO_0007167
DiseaseSalivary Gland Neoplasms

FAT1 JAG1 PYGB

1.43e-03471393C0036095
Diseaselung adenocarcinoma (is_implicated_in)

KMT2C PTPRJ ZFHX3

1.61e-03491393DOID:3910 (is_implicated_in)
Diseasemiddle temporal gyrus volume measurement, Alzheimer's disease biomarker measurement

SHC4 TOMM40

1.66e-03131392EFO_0006514, EFO_0010316
Diseaseretinitis pigmentosa (biomarker_via_orthology)

PTEN KL

1.66e-03131392DOID:10584 (biomarker_via_orthology)
DiseaseAlzheimer disease

DAPL1 PRICKLE1 DMXL1 CDR2L PKHD1 TOMM40 MYO15A TNXB

2.17e-034851398MONDO_0004975
Diseasehyperinsulinism (biomarker_via_orthology)

PTEN AGTR1

2.22e-03151392DOID:2018 (biomarker_via_orthology)
Diseaseneurofilament light chain measurement

DMXL1 NARF MYO15A

2.49e-03571393EFO_0009178
DiseaseT-Cell Lymphoma

KMT2D MGA

2.53e-03161392C0079772
Diseaseage at menopause

MGAM DOCK10 BIRC6 TASOR2 ZFHX4 MGA

3.15e-033021396EFO_0004704
Diseaselysophosphatidylcholine measurement

MGAM ROCK1 MGA

3.16e-03621393EFO_0010224
Diseasesmoking status measurement

SAMD9 NRAP RASGRF2 TRPC4 GRIK1 BIRC6 LNPEP ZNF804B PKHD1 ELAVL4 ZFHX3 HERC1 PCCA

3.37e-03116013913EFO_0006527
Diseaseinferior parietal cortex volume measurement

PRICKLE1 GRIK1

3.57e-03191392EFO_0010307
Diseaseobesity (implicated_via_orthology)

FAT4 DRD1 SERPINA12 ZFHX4 ZFHX3

3.58e-032151395DOID:9970 (implicated_via_orthology)
Diseaseend stage renal disease (implicated_via_orthology)

DRD1 C6

3.96e-03201392DOID:783 (implicated_via_orthology)
Diseasepolymyositis

LRP5 GNAO1

3.96e-03201392EFO_0003063
Diseasecoronary artery disease

FAT4 MAP7D3 CDKN2AIP VWDE DMXL1 R3HCC1L PTPRJ LNPEP FARP1 PKHD1 TOMM40 GNAO1 TNXB

4.29e-03119413913EFO_0001645
Diseasedisease of metabolism (implicated_via_orthology)

PTEN YTHDF3

4.36e-03211392DOID:0014667 (implicated_via_orthology)
DiseaseManic Disorder

DRD1 PACS1 TRANK1

4.63e-03711393C0024713
Diseasecardiomyopathy (implicated_via_orthology)

MYH1 MYH4 MYH8

4.63e-03711393DOID:0050700 (implicated_via_orthology)
Diseasebrain measurement, neuroimaging measurement

CDKN2AIP GPATCH8 MYLK2 ITIH5 JAG1 PYGB SNX31 ZFHX3

4.64e-035501398EFO_0004346, EFO_0004464

Protein segments in the cluster

PeptideGeneStartEntry
EFKINIPFDELKNYL

ALG11

371

Q2TAA5
NKENFIYLADFPKEL

CATSPERG

501

Q6ZRH7
PDNYDKDLSFIKVIN

PFKFB2

206

O60825
KALSIFNELRKQDPY

CDC23

281

Q9UJX2
DKRLEQSQPEYKALF

CDR2L

426

Q86X02
FDGQSALLYRLDKKP

CNTNAP3

186

Q9BZ76
NNAQYFLRKPDKAVE

BIRC6

1951

Q9NR09
PEDKLQIYRDNFEKA

CUL5

191

Q93034
LIYKDAPAFNEKASI

CCDC62

606

Q6P9F0
KVRLLNEYQKEAPSF

TBC1D32

291

Q96NH3
KQFQLYEEPDTKLAR

AKAP8

306

O43823
TLANPFLAKYRDFLK

AHSP

76

Q9NZD4
YEIQKNKPRNDDIFK

AGTR1

226

P30556
KHPSVDNKDLFYINL

GRIK1

136

P39086
KDINDNAPKFLKDFY

FAT4

1201

Q6V0I7
YNAARLLEAGKPFIK

ACADSB

351

P45954
QSKDFNPLTLYFREK

ADCY4

556

Q8NFM4
FVNYIDPKDAEKAIN

ELAVL4

96

P26378
QLDYEVPREKAFQKS

DNHD1

251

Q96M86
LNPIIYAFNADFRKA

DRD1

326

P21728
DKNSELFRKYALFSP

DIS3L2

256

Q8IYB7
FAYLAAKLDKNPNQV

CASP8AP2

1951

Q9UKL3
RIQAQENFAKKFPYR

C3orf22

16

Q8N5N4
AKAAFYRKNDPLDAA

DMXL1

1626

Q9Y485
DALNDALEKLNYKFP

DAPL1

61

A0PJW8
KAKARAYAEFLQPAK

R3HCC1L

716

Q7Z5L2
EFERSKRKNPAAYEN

UQCRQ

66

O14949
LLNKDLKPQTFRNAY

INTS6

531

Q9UL03
ISALDPAKKLQFYED

JAK3

726

P52333
AFLQRPYFDSKLNKN

FAT1

4226

Q14517
AAYENPRDKILVFKD

MMP27

331

Q9H306
NPFIYSLRNKEIKEA

OR6N1

286

Q8NGY5
PKYAAELAENRGKNR

PTPRJ

1056

Q12913
NDLSNLRFYKNKIPF

OGFRL1

116

Q5TC84
RKNKLEETFPAYLQE

KMT2C

1351

Q8NEZ4
LSRQPKDNQDIYKRF

NMS

56

Q5H8A3
FARNNAAKLIDGEYK

ITIH5

906

Q86UX2
QLKIDYNPFAKGFRD

MGA

246

Q8IWI9
YKLRLDALPFQAAKA

NRAP

1041

Q86VF7
KKDSDYVVAVRNFLP

MYO15A

2866

Q9UKN7
SYNKINQLRPKEFED

LRRC17

276

Q8N6Y2
YKDPNNLAFNEIKIL

MGAM

891

O43451
TYKDPNNLAFNEIKI

MGAM

1786

O43451
LSGNEEQKPFDYKLR

HERC1

1201

Q15751
LRNVKAIDYDPLDKF

LRP5

976

O75197
IEDIGNKRKYDFPLN

LOXHD1

256

Q8IVV2
EDVKQKQPFFNRLYK

CDKN2AIP

431

Q9NXV6
LALIQEKTKNRYFPA

GSTA2

121

P09210
LNQQDVPDKFKYKAD

EIF2B1

241

Q14232
PLYFDFKLSRNKDAR

GPATCH8

571

Q9UKJ3
FKQRYKVLNASAIPE

MYH8

721

P13535
PLLNDYKQDFFLKRF

PCNX4

6

Q63HM2
KKLNRVEPNLDAALY

MMP19

371

Q99542
DFGLARRYNPNEKLK

MYLK2

426

Q9H1R3
NPQFAKEYFDRKLRV

PDE6C

16

P51160
KKYFAATQFEPLAAR

LNPEP

286

Q9UIQ6
INVDYKKLFPNGLRD

GDPD4

401

Q6W3E5
KKLFPNGLRDYKAAN

GDPD4

406

Q6W3E5
DFKQRYKVLNASAIP

MYH1

721

P12882
NPVIYSLRNKDFKEA

OR11L1

286

Q8NGX0
YDPNEKTFDKILVAN

PCCA

56

P05165
LKDRDPEFYKFLQEN

NOC2L

76

Q9Y3T9
SLQYPHFLKRDANKL

PACS1

176

Q6VY07
LYNKTKPFQLQLDAF

HMMR

586

O75330
PDNYEKFIQNKSARE

PRICKLE1

706

Q96MT3
QRLLKLYADKFGADN

DOCK10

1911

Q96BY6
NLRKALQEYAAKFDP

C6

506

P13671
RLEKFPDEKAAYFRN

DOK6

41

Q6PKX4
FPLNAIYAKPANKQE

ARPC3

111

O15145
FLIKLRPDANSAYQD

FARP1

276

Q9Y4F1
LQFAYFKANNLPKAI

CRTAP

151

O75718
DNTPKRKYQDFLDIV

CYP4X1

276

Q8N118
KISNIPDEYFKRFNA

LUM

216

P51884
DDNIKKYLNKDPRDF

HEPHL1

941

Q6MZM0
EPKTYFNGDLKNFRQ

MAP7D3

801

Q8IWC1
AANYNDINDVKRLKP

PPA1

166

Q15181
EYAKPTRLNVFKNDQ

HNRNPL

266

P14866
RNNFLLPYFTEDEKK

KL

781

Q9UEF7
KLKQDPYLVNFFLEN

FHIP2A

161

Q5W0V3
AKYKGPALALEFNRS

HELZ2

316

Q9BYK8
PALKDFLFQAKYQIR

CRLF1

261

O75462
YPDAKKRSLINEFDL

SLC22A14

161

Q9Y267
ANNQIKEAIDKRYLP

CDC27

771

P30260
KNFAELYESFQNPKR

PEX1

1251

O43933
NVFYRPKDKQALADQ

DHX8

1016

Q14562
DKANKDKANRYFSPN

PTEN

326

P60484
DKANRYFSPNFKVKL

PTEN

331

P60484
QKARFAKQPAYTLVD

JAG1

1166

P78504
ELYREAPIDKKGNFN

MYL12B

141

O14950
LQYPGKFKLLEQARD

GAREM2

81

Q75VX8
NDKLFPLRNKEAGRY

RTN3

291

O95197
DAPLFYREEGNKKFQ

SMYD4

66

Q8IYR2
LRAYRAQKNLDFEDP

SHD

31

Q96IW2
ASARALYRLAQKKPF

FARSA

331

Q9Y285
DLDDPVNRAKKYFLQ

PUS7L

466

Q9H0K6
NRDFDKLLKQYEANP

RASGRF2

356

O14827
FDEYFVLLKPRNNIK

SAMD9

1271

Q5K651
AQFESKNRSPNKEIY

GNAO1

306

P09471
FARALKYLPKTLAEN

CCT8L1P

441

A6NM43
DFKQRYKVLNASAIP

MYH4

721

Q9Y623
QFAPEYEKIANILKD

PDIA4

96

P13667
QDSAIKDFVLKYALP

PDIA4

381

P13667
DKNKFYFPSLQPRKD

PKHD1

3321

P08F94
IAADLANYAPAKNRK

SCFD2

246

Q8WU76
EAAYREKNSKPELFN

POU4F3

256

Q15319
DIATKKAYLDIFLPN

SNX31

111

Q8N9S9
PQRKFLEDAKNFYSA

SERPINA12

146

Q8IW75
KYQGQDFLPKDQDFL

CCDC15

526

Q0P6D6
VAEVTYKPLRNKDFQ

CIAO3

336

Q9H6Q4
AALDRFKNRLKDYPQ

CNOT1

956

A5YKK6
QAFELRFKQYLKNPS

SHC4

336

Q6S5L8
ALDQFQEKYSRKPNV

UBA6

331

A0AVT1
SPEEYNLNLFLQEKK

VWDE

686

Q8N2E2
EKLKAINNYNPKDFD

YTHDF3

396

Q7Z739
LFKERQRNKDSPYNF

ZFHX4

2136

Q86UP3
YALEDDPLAAFKQRQ

TIMM50

301

Q3ZCQ8
NPLYFDFKLSRNTKE

ZNF804B

476

A4D1E1
QDQEYIKPRLRFKAF

UBXN2B

201

Q14CS0
AQKDFLKALHINPAY

TTC6

266

Q86TZ1
KAAKEYPFILDAFQR

MTREX

131

P42285
YPNDNFFEGKELRLK

PYGM

281

P11217
AKPNRKLTFLYLAND

RPRD1A

51

Q96P16
KKDYERVLELEPNNF

RPAP3

221

Q9H6T3
NFALRLYKELAADAP

SERPINA11

56

Q86U17
DRQGFVPAAYVKKLD

SPTAN1

1011

Q13813
DPARKYKFLLFGLQN

TNXB

3321

P22105
SPLYALDRKAVAKDN

KCNJ16

261

Q9NPI9
YPNDNFFEGKELRLK

PYGB

281

P11216
EFKYNKPAFLKNARQ

UBE2T

131

Q9NPD8
RTANKDPIKAFYENR

TTC3

356

P53804
FTELKFYQRAAKPEQ

VRK1

81

Q99986
ALVYDLDFPALRKNK

ROCK1

36

Q13464
FGYQLDLPKANLLFK

TOMM40

301

O96008
FAKDLRPEQYIKNSF

ZNF708

81

P17019
ALALRFDKPIKQAFY

TMEM245

41

Q9H330
FLYSLNRTLKDKADP

WDR93

391

Q6P2C0
KRLPEAAFRKQNYLE

TASOR2

66

Q5VWN6
IFDENREKRAPAFKY

TRANK1

1656

O15050
YPNDNFFEGKELRLK

PYGL

281

P06737
LAIKYRQKEFVAQPN

TRPC4

291

Q9UBN4
TLFKERQRNKDSPYN

ZFHX3

2196

Q15911
DKAPYLQKAKDNRAA

KMT2D

2056

O14686
AALLKYNEAVKLAPN

LONRF3

261

Q496Y0
KDYFARQQNLSPEKI

NARF

206

Q9UHQ1
AAFTKKLDPAYQVDR

MYBPC2

256

Q14324