Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionbenzodiazepine receptor binding

RIMBP3 RIMBP3C RIMBP3B

7.97e-0651873GO:0030156
GeneOntologyBiologicalProcessneuron projection development

SLC25A46 EPHB3 ERBB2 ATCAY ROR1 PCDHAC2 CDH23 DGKG ALS2 ITGA1 ADGRV1 TENM2 SEMA4G CRMP1 PTPRD TENM3 FCGR2A SIPA1L1 UNC5C NECTIN1 NR2E1 PCDH15 PLXNA4 LRP6 ADAM17 GRIN3A OLIG1 PLXNA1 NOTCH1 EPHA7

1.19e-06128518430GO:0031175
GeneOntologyBiologicalProcessneuron development

SLC25A46 EPHB3 ERBB2 ATCAY ROR1 PCDHAC2 CDH23 DGKG ALS2 ITGA1 ADGRV1 LHX8 TENM2 SEMA4G CRMP1 PTPRD TENM3 FCGR2A SIPA1L1 UNC5C NECTIN1 NR2E1 PCDH15 PLXNA4 LRP6 ADAM17 GRIN3A OLIG1 PLXNA1 NOTCH1 EPHA7

5.74e-06146318431GO:0048666
GeneOntologyBiologicalProcessneuron projection guidance

EPHB3 ERBB2 PCDHAC2 TENM2 SEMA4G UNC5C NECTIN1 PLXNA4 ADAM17 PLXNA1 NOTCH1 EPHA7

1.05e-0528618412GO:0097485
GeneOntologyBiologicalProcesssensory perception of sound

HEXB COL11A1 ROR1 CDH23 FBXO11 ADGRV1 TUB CRYM PCDH15 USH2A

1.19e-0519818410GO:0007605
GeneOntologyBiologicalProcesscell morphogenesis

SLC25A46 EPHB3 HEXB ERBB2 PCDHAC2 CDH23 ALS2 ITGA1 TENM2 POF1B SEMA4G PTPN6 PTPRD SIPA1L1 UNC5C NECTIN1 NR2E1 PCDH15 PLXNA4 LRP6 ADAM17 PLEC PHIP PLXNA1 NOTCH1 EPHA7

2.26e-05119418426GO:0000902
GeneOntologyBiologicalProcesscell-cell adhesion

EPHB3 ERBB2 TBX21 PCDHAC2 CDH23 ITGA1 ADGRV1 FOXA2 TENM2 SVEP1 JUP PTPN6 CELSR1 PTPRD TENM3 LRFN5 NECTIN1 CTNNA3 PCDH15 LRP6 MAP2K5 PHF10 NOTCH1 EPHA7

3.33e-05107718424GO:0098609
GeneOntologyBiologicalProcesstrans-synaptic signaling

ALS2 GRIK2 TENM2 RIMBP3 SLC32A1 ZDHHC12 PTPRD FCGR2A NISCH SIPA1L1 NR2E1 LRP6 SV2C PRKCG RIMBP3C FGF14 GRIN3A RIMBP3B RAB5A NOTCH1 JPH3 EPHA7

3.47e-0593918422GO:0099537
GeneOntologyBiologicalProcesscell morphogenesis involved in neuron differentiation

SLC25A46 EPHB3 ERBB2 PCDHAC2 CDH23 ALS2 TENM2 SEMA4G PTPRD SIPA1L1 UNC5C NECTIN1 NR2E1 PCDH15 PLXNA4 ADAM17 PLXNA1 NOTCH1 EPHA7

4.21e-0574818419GO:0048667
GeneOntologyBiologicalProcessaxonogenesis

SLC25A46 EPHB3 ERBB2 PCDHAC2 ALS2 TENM2 SEMA4G SIPA1L1 UNC5C NECTIN1 NR2E1 PLXNA4 ADAM17 PLXNA1 NOTCH1 EPHA7

5.04e-0556618416GO:0007409
GeneOntologyBiologicalProcessaxon guidance

EPHB3 ERBB2 PCDHAC2 TENM2 SEMA4G UNC5C NECTIN1 PLXNA4 ADAM17 NOTCH1 EPHA7

5.29e-0528518411GO:0007411
GeneOntologyBiologicalProcesssensory perception of mechanical stimulus

HEXB COL11A1 ROR1 CDH23 FBXO11 ADGRV1 TUB CRYM PCDH15 USH2A

5.75e-0523818410GO:0050954
GeneOntologyBiologicalProcessphotoreceptor cell maintenance

CDH23 ADGRV1 TUB PCDH15 USH2A

6.06e-05471845GO:0045494
GeneOntologyBiologicalProcesssynaptic signaling

ALS2 GRIK2 TENM2 RIMBP3 SLC32A1 ZDHHC12 PTPRD FCGR2A NISCH SIPA1L1 NR2E1 LRP6 SV2C PRKCG RIMBP3C FGF14 GRIN3A RIMBP3B RAB5A NOTCH1 JPH3 EPHA7

6.15e-0597618422GO:0099536
GeneOntologyBiologicalProcessaxon development

SLC25A46 EPHB3 ERBB2 PCDHAC2 ALS2 TENM2 SEMA4G SIPA1L1 UNC5C NECTIN1 NR2E1 PLXNA4 ADAM17 OLIG1 PLXNA1 NOTCH1 EPHA7

6.55e-0564218417GO:0061564
GeneOntologyBiologicalProcessanterograde trans-synaptic signaling

ALS2 GRIK2 RIMBP3 SLC32A1 ZDHHC12 PTPRD FCGR2A NISCH SIPA1L1 NR2E1 LRP6 SV2C PRKCG RIMBP3C FGF14 GRIN3A RIMBP3B RAB5A NOTCH1 JPH3 EPHA7

9.05e-0593118421GO:0098916
GeneOntologyBiologicalProcesschemical synaptic transmission

ALS2 GRIK2 RIMBP3 SLC32A1 ZDHHC12 PTPRD FCGR2A NISCH SIPA1L1 NR2E1 LRP6 SV2C PRKCG RIMBP3C FGF14 GRIN3A RIMBP3B RAB5A NOTCH1 JPH3 EPHA7

9.05e-0593118421GO:0007268
GeneOntologyBiologicalProcesssemaphorin-plexin signaling pathway

ERBB2 SEMA4G CRMP1 PLXNA4 PLXNA1

9.90e-05521845GO:0071526
GeneOntologyBiologicalProcessregulation of transferase activity

MAPK8IP1 ERBB2 PDGFRB ROR1 CBLC ALS2 CCT2 CHI3L1 FOXA2 FEM1B PPP2CA NEK2 PTPN6 PTPRB LRP6 ADAM17 ATM PLEC MAP2K5

1.20e-0481018419GO:0051338
GeneOntologyBiologicalProcessnegative regulation of humoral immune response mediated by circulating immunoglobulin

SVEP1 PTPN6 FCGR2A

1.45e-04121843GO:0002924
GeneOntologyBiologicalProcesscentral nervous system development

SLC25A46 EPHB3 EEF1AKMT4-ECE2 ERBB2 MBOAT7 ROR1 MSI1 LHX8 FOXA2 SLC32A1 CELSR1 KCNC1 KCNC2 FCGR2A UNC5C NR2E1 PLXNA4 LRP6 KDM4A ATM OLIG1 PLXNA1 NOTCH1 EPHA7

1.71e-04119718424GO:0007417
GeneOntologyBiologicalProcessretina homeostasis

CDH23 ADGRV1 TUB PCDH15 USH2A

2.66e-04641845GO:0001895
GeneOntologyCellularComponentdistal axon

MAPK8IP1 ATCAY ROR1 ALS2 GRIK2 TENM2 CRMP1 SLC32A1 PPP2CA KCNC1 KCNC2 UNC5C NECTIN1 PRKCG USH2A RAB5A

1.75e-0643518516GO:0150034
GeneOntologyCellularComponentcell surface

VWF IQGAP2 UPK1A PDGFRB ENPP3 ROR1 CD109 CP ITGA1 ADGRV1 LCT SLC32A1 FCGR2C SLC12A1 KCNC1 FCGR2A MUC17 LRFN5 UNC5C AOC3 SCNN1B LRP6 TRPM8 ADAM17 TNS1 NOTCH1

5.61e-06111118526GO:0009986
GeneOntologyCellularComponentapical plasma membrane

ERBB2 UPK1A PDGFRB ENPP3 LCT SLC3A1 SLC12A1 KCNC2 MUC17 PRKAB2 SCNN1B ADAM17 PLEC USH2A NOTCH1

3.03e-0548718515GO:0016324
GeneOntologyCellularComponentneuron projection terminus

ATCAY ROR1 GRIK2 SLC32A1 PPP2CA KCNC1 KCNC2 PRKCG USH2A RAB5A

4.50e-0523318510GO:0044306
GeneOntologyCellularComponentjunctional membrane complex

JPH2 JPH1 JPH3

5.51e-0591853GO:0030314
GeneOntologyCellularComponentdendrite

EPHB3 MAPK8IP1 ATCAY ALS2 GRIK2 TENM2 CRMP1 SLC32A1 CNNM1 PTPN6 KCNC1 KCNC2 FCGR2A SIPA1L1 UNC5C NECTIN1 PRKCG PLEC RAB5A EPHA7

7.76e-0585818520GO:0030425
GeneOntologyCellularComponentapical part of cell

ERBB2 UPK1A PDGFRB ENPP3 CDH23 LCT SLC3A1 SLC12A1 KCNC2 MUC17 PRKAB2 SCNN1B ADAM17 PLEC USH2A NOTCH1

7.80e-0559218516GO:0045177
GeneOntologyCellularComponentjunctional sarcoplasmic reticulum membrane

JPH2 JPH1 JPH3

7.82e-05101853GO:0014701
GeneOntologyCellularComponentdendritic tree

EPHB3 MAPK8IP1 ATCAY ALS2 GRIK2 TENM2 CRMP1 SLC32A1 CNNM1 PTPN6 KCNC1 KCNC2 FCGR2A SIPA1L1 UNC5C NECTIN1 PRKCG PLEC RAB5A EPHA7

8.01e-0586018520GO:0097447
GeneOntologyCellularComponentsomatodendritic compartment

EPHB3 MAPK8IP1 ATCAY TBX21 ALS2 GRIK2 ITGA1 TENM2 CRMP1 SLC32A1 CNNM1 PTPN6 KCNC1 KCNC2 FCGR2A SIPA1L1 UNC5C NECTIN1 LRP6 PRKCG GRIN3A PLEC USH2A RAB5A EPHA7

8.62e-05122818525GO:0036477
GeneOntologyCellularComponentaxon terminus

ROR1 GRIK2 SLC32A1 PPP2CA KCNC1 KCNC2 PRKCG USH2A RAB5A

1.10e-042101859GO:0043679
GeneOntologyCellularComponentpresynapse

ERBB2 ATCAY ROR1 GRIK2 CRMP1 SLC32A1 PPP2CA PTPRD TENM3 KCNC1 KCNC2 NECTIN1 SV2C PRKCG ATM GRIN3A USH2A RAB5A RAB5B RAB5C

1.20e-0488618520GO:0098793
GeneOntologyCellularComponentcluster of actin-based cell projections

CORO2A CDH23 ADGRV1 LCT SLC3A1 MUC17 PCDH15 PLEC USH2A

1.73e-042231859GO:0098862
GeneOntologyCellularComponentsemaphorin receptor complex

ERBB2 PLXNA4 PLXNA1

1.83e-04131853GO:0002116
GeneOntologyCellularComponentactin-based cell projection

ERBB2 IQGAP2 CDH23 ADGRV1 TENM2 MUC17 UNC5C AOC3 PCDH15 USH2A

1.93e-0427818510GO:0098858
GeneOntologyCellularComponentchromosomal region

MCM3 TFIP11 MSH2 XPO1 DDB1 PPP2CA PPP2CB NEK2 NAT10 KDM4A ATM PHF10

3.88e-0442118512GO:0098687
GeneOntologyCellularComponentUSH2 complex

ADGRV1 USH2A

4.62e-0441852GO:1990696
GeneOntologyCellularComponentcell leading edge

ERBB2 IQGAP2 PDGFRB ALS2 ADGRV1 KCNC1 KCNC2 UNC5C CTNNA3 ADAM17 USH2A RAB5A PLCE1

5.33e-0450018513GO:0031252
GeneOntologyCellularComponentsynaptic membrane

ERBB2 GRIK2 TENM2 PTPRD TENM3 KCNC1 KCNC2 LRFN5 NECTIN1 PRKCG GRIN3A RAB5A NOTCH1 EPHA7

7.15e-0458318514GO:0097060
GeneOntologyCellularComponentaxon

MAPK8IP1 ATCAY ROR1 ALS2 GRIK2 TENM2 CRMP1 SLC32A1 PPP2CA TENM3 KCNC1 KCNC2 UNC5C NECTIN1 PRKCG PLEC USH2A RAB5A

9.73e-0489118518GO:0030424
GeneOntologyCellularComponentstereocilia ankle link

ADGRV1 USH2A

1.14e-0361852GO:0002141
GeneOntologyCellularComponentstereocilia ankle link complex

ADGRV1 USH2A

1.14e-0361852GO:0002142
GeneOntologyCellularComponentstereocilium membrane

ADGRV1 USH2A

1.14e-0361852GO:0060171
GeneOntologyCellularComponentpericiliary membrane compartment

ADGRV1 USH2A

1.14e-0361852GO:1990075
GeneOntologyCellularComponentcell body

MAPK8IP1 TBX21 ALS2 CCT2 GRIK2 ITGA1 CRMP1 CNNM1 KCNC1 KCNC2 FCGR2A SIPA1L1 UNC5C LRP6 GRIN3A USH2A RAB5A EPHA7

1.55e-0392918518GO:0044297
GeneOntologyCellularComponentterminal bouton

GRIK2 PPP2CA KCNC2 USH2A RAB5A

1.64e-03961855GO:0043195
GeneOntologyCellularComponentmanchette

RIMBP3 RIMBP3C RIMBP3B

1.90e-03281853GO:0002177
GeneOntologyCellularComponentdesmosome

POF1B JUP CTNNA3

1.90e-03281853GO:0030057
GeneOntologyCellularComponentreceptor complex

ERBB2 COL10A1 PDGFRB ROR1 GRIK2 ITGA1 ADGRV1 PTPN6 PTPRB PLXNA4 GRIN3A PLXNA1 NOTCH1

2.07e-0358118513GO:0043235
GeneOntologyCellularComponentstereocilia coupling link

ADGRV1 USH2A

2.11e-0381852GO:0002139
GeneOntologyCellularComponentproteasome core complex, alpha-subunit complex

PSMA3 PSMA4

2.11e-0381852GO:0019773
GeneOntologyCellularComponenthippocampal mossy fiber to CA3 synapse

GRIK2 PTPRD NECTIN1 EPHA7

2.95e-03671854GO:0098686
GeneOntologyCellularComponentneuronal cell body

MAPK8IP1 TBX21 ALS2 GRIK2 ITGA1 CRMP1 CNNM1 KCNC1 KCNC2 SIPA1L1 UNC5C LRP6 GRIN3A USH2A RAB5A EPHA7

3.14e-0383518516GO:0043025
GeneOntologyCellularComponentstereocilium

CDH23 ADGRV1 PCDH15 USH2A

3.28e-03691854GO:0032420
GeneOntologyCellularComponentpostsynaptic membrane

ERBB2 GRIK2 TENM2 KCNC1 KCNC2 LRFN5 GRIN3A RAB5A NOTCH1 EPHA7

3.36e-0340518510GO:0045211
GeneOntologyCellularComponentsecretory vesicle

HEXB VWF IQGAP2 CD109 HGSNAT CCT2 ITGA1 CHI3L1 SLC32A1 SYT15 JUP PTPN6 PTPRB FCGR2A AGA SV2C ATM RAB5A RAB5B NOTCH1 RAB5C

3.46e-03124618521GO:0099503
GeneOntologyCellularComponenthemidesmosome

JUP PLEC

4.07e-03111852GO:0030056
MousePhenoabnormal orientation of outer hair cell stereociliary bundles

CDH23 ADGRV1 CELSR1 PCDH15 LRP6

6.19e-06241585MP:0004491
MousePhenoabnormal mechanoreceptor morphology

ERBB2 COL11A1 ROR1 SLC19A2 CDH23 ADGRV1 TUB CELSR1 PCDH15 LRP6 USH2A NOTCH1

1.23e-0523115812MP:0000972
MousePhenoabnormal cochlear outer hair cell morphology

COL11A1 SLC19A2 CDH23 ADGRV1 TUB CELSR1 PCDH15 LRP6 USH2A NOTCH1

1.29e-0515915810MP:0004399
MousePhenoabnormal cochlear hair cell morphology

COL11A1 ROR1 SLC19A2 CDH23 ADGRV1 TUB CELSR1 PCDH15 LRP6 USH2A NOTCH1

1.85e-0520215811MP:0002622
MousePhenoabnormal cochlear sensory epithelium morphology

COL11A1 ROR1 SLC19A2 CDH23 ADGRV1 TUB CELSR1 PCDH15 LRP6 USH2A NOTCH1

2.32e-0520715811MP:0003308
MousePhenoabnormal organ of Corti morphology

COL11A1 ROR1 SLC19A2 CDH23 ADGRV1 TUB CELSR1 PCDH15 LRP6 USH2A NOTCH1

2.53e-0520915811MP:0000042
MousePhenoabnormal outer hair cell kinocilium location or orientation

CDH23 CELSR1 PCDH15

2.76e-0561583MP:0030961
MousePhenoabnormal hair cell morphology

COL11A1 ROR1 SLC19A2 CDH23 ADGRV1 TUB CELSR1 PCDH15 LRP6 USH2A NOTCH1

3.15e-0521415811MP:0000045
MousePhenoneuron degeneration

HEXB PDGFRB ATCAY SLC19A2 CDH23 CP MSI1 ADGRV1 TUB PTPN6 CELSR1 AGA PCDH15 ATM USH2A

3.71e-0539115815MP:0003224
MousePhenoabnormal somatic sensory system morphology

SLC25A46 ERBB2 COL11A1 PDGFRB ROR1 SLC19A2 CDH23 MSI1 ADGRV1 TUB TENM2 PTPN6 CELSR1 TENM3 NR2E1 PCDH15 PLXNA4 LRP6 OLIG1 USH2A NOTCH1

4.23e-0570215821MP:0000959
MousePhenoabnormal orientation of cochlear hair cell stereociliary bundles

CDH23 ADGRV1 CELSR1 PCDH15 LRP6

4.27e-05351585MP:0004522
MousePhenoataxia

SLC25A46 HEXB ATCAY SLC19A2 CDH23 MSI1 AGA UNC5C PCDH15 PRKCG FGF14 ATM

4.94e-0526615812MP:0001393
MousePhenofailure of eyelid fusion

ALX4 NECTIN1 LRP6 ADAM17

6.61e-05201584MP:0009264
MousePhenoabnormal cochlear labyrinth morphology

COL11A1 ROR1 SLC19A2 CDH23 ADGRV1 TUB CELSR1 PCDH15 LRP6 USH2A NOTCH1

7.37e-0523515811MP:0004426
MousePhenoabnormal scala media morphology

COL11A1 ROR1 SLC19A2 CDH23 ADGRV1 TUB CELSR1 PCDH15 LRP6 USH2A NOTCH1

7.37e-0523515811MP:0003169
MousePhenoneurodegeneration

HEXB PDGFRB ATCAY SLC19A2 CDH23 CP ALS2 MSI1 ADGRV1 TUB PTPN6 CELSR1 AGA PCDH15 ATM USH2A

8.03e-0546815816MP:0002229
MousePhenoabnormal sensory neuron morphology

SLC25A46 ERBB2 COL11A1 PDGFRB ROR1 CDH23 MSI1 TUB TENM2 PTPN6 TENM3 NR2E1 PLXNA4 OLIG1 USH2A NOTCH1

9.09e-0547315816MP:0000965
MousePhenoabnormal Purkinje cell morphology

SLC25A46 HEXB HGSNAT DGKG CP ALS2 AGA UNC5C PRKCG ATM

1.08e-0420415810MP:0000877
MousePhenoabnormal cochlear hair cell inter-stereocilial links morphology

CDH23 ADGRV1 PCDH15

1.13e-0491583MP:0004577
MousePhenoabnormal cochlea morphology

COL11A1 ROR1 SLC19A2 CDH23 ADGRV1 TUB CELSR1 PCDH15 LRP6 USH2A NOTCH1

1.19e-0424815811MP:0000031
MousePhenoabnormal outer hair cell kinocilium morphology

CDH23 CELSR1 PCDH15

1.60e-04101583MP:0011062
MousePhenoabnormal membranous labyrinth morphology

COL11A1 ROR1 SLC19A2 CDH23 ADGRV1 TUB CELSR1 PCDH15 LRP6 USH2A NOTCH1

1.93e-0426215811MP:0000035
MousePhenoabnormal cerebellar Purkinje cell layer

SLC25A46 HEXB HGSNAT DGKG CP ALS2 AGA UNC5C PRKCG ATM

2.00e-0422015810MP:0000875
MousePhenocochlear ganglion hypoplasia

CDH23 ADGRV1 PCDH15

2.19e-04111583MP:0003637
MousePhenoabnormal CNS glial cell morphology

SLC25A46 ERBB2 HGSNAT CHSY1 CP ALS2 PTPN6 AGA NR2E1 OLIG1 PLXNA1

2.66e-0427215811MP:0000952
MousePhenohead bobbing

CDH23 CELSR1 NISCH UNC5C PCDH15

2.67e-04511585MP:0001410
MousePhenoabnormal eyelid fusion

ALX4 NECTIN1 LRP6 ADAM17

2.99e-04291584MP:0009263
MousePhenoorgan of Corti degeneration

COL11A1 CDH23 ADGRV1 TUB PCDH15

3.21e-04531585MP:0000043
MousePhenoabnormal innervation

ERBB2 ROR1 ALS2 TENM2 TENM3 AGA UNC5C PLXNA4 PRKCG

3.46e-041931589MP:0002184
MousePhenoabnormal eyelid development

ALX4 NECTIN1 LRP6 ADAM17

3.90e-04311584MP:0009651
MousePhenoabnormal distortion product otoacoustic emission

ROR1 SLC19A2 CDH23 ADGRV1 PCDH15 USH2A

3.97e-04851586MP:0004736
MousePhenocochlear outer hair cell degeneration

SLC19A2 CDH23 ADGRV1 TUB CELSR1 PCDH15

4.23e-04861586MP:0004404
MousePhenoabnormal otoacoustic response

ROR1 SLC19A2 CDH23 ADGRV1 PCDH15 USH2A

4.23e-04861586MP:0006336
MousePhenocochlear inner hair cell degeneration

SLC19A2 CDH23 ADGRV1 TUB PCDH15

4.51e-04571585MP:0004398
MousePhenoabnormal hair cell mechanoelectric transduction

CDH23 ADGRV1 PCDH15

4.71e-04141583MP:0004431
MousePhenoeyelids open at birth

FBXO11 ALX4 FOXL2 NECTIN1 ADAM17

4.89e-04581585MP:0001302
DomainJunctophilin

JPH2 JPH1 JPH3

3.68e-0641833IPR017191
DomainMORN

JPH2 ALS2 JPH1 JPH3

8.27e-06141834SM00698
DomainMORN

JPH2 ALS2 JPH1 JPH3

1.12e-05151834IPR003409
DomainMORN

JPH2 ALS2 JPH1 JPH3

1.12e-05151834PF02493
DomainIg-like_fold

EPHB3 PDGFRB ROR1 REL SEMA4G RIMBP3 SNED1 PTPRB PTPRD FCGR2A LRFN5 UNC5C NECTIN1 PRKAB2 PLXNA4 RIMBP3C RIMBP3B USH2A PLXNA1 EPHA7

2.08e-0570618320IPR013783
DomainFN3

EPHB3 RIMBP3 SNED1 PTPRB PTPRD LRFN5 RIMBP3C RIMBP3B USH2A EPHA7

2.76e-0519918310PS50853
Domain-

EPHB3 PDGFRB ROR1 REL SEMA4G RIMBP3 SNED1 PTPRB PTPRD FCGR2A LRFN5 UNC5C NECTIN1 PLXNA4 RIMBP3C RIMBP3B USH2A PLXNA1 EPHA7

2.89e-05663183192.60.40.10
DomainFN3_dom

EPHB3 RIMBP3 SNED1 PTPRB PTPRD LRFN5 RIMBP3C RIMBP3B USH2A EPHA7

4.18e-0520918310IPR003961
DomainIg_E-set

CD109 REL ARHGDIG A2ML1 PRKAB2 PLXNA4 PLXNA1

7.38e-051041837IPR014756
DomainEphrin_rec_like

EPHB3 SVEP1 EPHA7

1.44e-04111833PF07699
DomainEGF-like_CS

TENM2 SVEP1 SNED1 CELSR1 TENM3 MUC17 LRP6 ADAM17 NOTCH1 EPHA7

2.61e-0426118310IPR013032
DomainRhs_assc_core

TENM2 TENM3

2.85e-0431832IPR022385
Domain-

HEXB CHI3L1 LCT SLC3A1

3.68e-043518343.20.20.80
DomainSer-Thr/Tyr_kinase_cat_dom

EPHB3 ERBB2 PDGFRB ROR1 PRKX PRKY EPHA7

4.26e-041381837IPR001245
DomainFN3

EPHB3 SNED1 PTPRB PTPRD RIMBP3C RIMBP3B USH2A EPHA7

4.88e-041851838SM00060
DomainGlyco_hydro_catalytic_dom

HEXB CHI3L1 LCT SLC3A1

5.07e-04381834IPR013781
DomainTox-GHH_dom

TENM2 TENM3

5.66e-0441832IPR028916
DomainTox-GHH

TENM2 TENM3

5.66e-0441832PF15636
DomainK_chnl_volt-dep_Kv3

KCNC1 KCNC2

5.66e-0441832IPR003974
DomainTen_N

TENM2 TENM3

5.66e-0441832IPR009471
DomainTen_N

TENM2 TENM3

5.66e-0441832PF06484
DomainTENEURIN_N

TENM2 TENM3

5.66e-0441832PS51361
Pubmed

Biochemical characterization of native Usher protein complexes from a vesicular subfraction of tracheal epithelial cells.

CDH23 ADGRV1 PCDH15 USH2A

2.86e-087188420058854
Pubmed

Molecular patterning of the embryonic cranial mesenchyme revealed by genome-wide transcriptional profiling.

EPHB3 VWF VEPH1 CP SNED1 UNC5C EPHA7

3.24e-0859188731351040
Pubmed

Large-scale proteomics and phosphoproteomics of urinary exosomes.

VWF IQGAP2 UPK1A ENPP3 PSMA3 PSMA4 AOX1 CP CCT2 ITGA1 ADGRV1 DDB1 SLC3A1 C16orf89 JUP PTPN6 CRYM FBP1 SLC12A1 TMPRSS2 RAB5B RAB5C

3.78e-0810161882219056867
Pubmed

ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.

HEXB FKBP10 ERBB2 MBOAT7 CD109 CHSY1 GRIK2 ITGA1 DDB1 STT3B OSTC JUP CELSR1 MGAT5 TENM3 SEL1L3 LRP6 CHSY3 ADAM17 ATM SELENOI PLXNA1 NOTCH1 RAB5C

3.93e-0812011882435696571
Pubmed

Microarray-based mutation analysis of 183 Spanish families with Usher syndrome.

CDH23 ADGRV1 PCDH15 USH2A

5.69e-088188419683999
Pubmed

Irisin Mediates Effects on Bone and Fat via αV Integrin Receptors.

HEXB FKBP10 MBOAT7 PDGFRB PSMA3 CD109 MCM3 CP CCT2 BCKDHA ACAD10 ITGA1 XPO1 COQ3 DDB1 STT3B SNED1 AGA UNC5C ADAM17 PLEC RAB5A RAB5B PLXNA1 SDHA RAB5C

8.82e-0814511882630550785
Pubmed

Characterization of human junctophilin subtype genes.

JPH2 JPH1 JPH3

1.55e-073188310891348
Pubmed

Junctophilins: a novel family of junctional membrane complex proteins.

JPH2 JPH1 JPH3

1.55e-073188310949023
Pubmed

Junctophilins 1, 2, and 3 all support voltage-induced Ca2+ release despite considerable divergence.

JPH2 JPH1 JPH3

1.55e-073188335089322
Pubmed

Rab5 is necessary for the biogenesis of the endolysosomal system in vivo.

RAB5A RAB5B RAB5C

1.55e-073188322622570
Pubmed

Massively parallel DNA sequencing facilitates diagnosis of patients with Usher syndrome type 1.

CDH23 ADGRV1 PCDH15 USH2A

1.69e-0710188424618850
Pubmed

Usher protein functions in hair cells and photoreceptors.

CDH23 ADGRV1 PCDH15 USH2A

1.69e-0710188424239741
Pubmed

Candidate gene/loci studies in cleft lip/palate and dental anomalies finds novel susceptibility genes for clefts.

EPHB3 ERBB2 LHX8 SCML4 FBP1 NECTIN1 ADAM17

2.52e-0779188718978678
Pubmed

PlexinA1 signaling directs the segregation of proprioceptive sensory axons in the developing spinal cord.

EPHB3 SEMA4G LRFN5 NECTIN1 PLXNA4 PRKCG PLXNA1 EPHA7

2.59e-07117188817145500
Pubmed

Strain background effects and genetic modifiers of hearing in mice.

CDH23 ADGRV1 TUB PCDH15

2.65e-0711188416579977
Pubmed

Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.

HEXB MAPK8IP1 SETMAR VWF PDGFRB CORO2A PSMA3 FBXO11 TFIP11 CCT2 CRMP1 JPH1 PTPRD NISCH SIPA1L1 USP32 KDM4A CHD6 ATM PLEC RAB5B SDHA JPH3

5.34e-0712851882335914814
Pubmed

RIM-BP3 is a manchette-associated protein essential for spermiogenesis.

RIMBP3 RIMBP3C RIMBP3B

6.19e-074188319091768
Pubmed

Usher syndromes due to MYO7A, PCDH15, USH2A or GPR98 mutations share retinal disease mechanism.

ADGRV1 PCDH15 USH2A

6.19e-074188318463160
Pubmed

Role for a novel Usher protein complex in hair cell synaptic maturation.

CDH23 ADGRV1 PCDH15

6.19e-074188322363448
Pubmed

Interaction of protocadherin-15 with the scaffold protein whirlin supports its anchoring of hair-bundle lateral links in cochlear hair cells.

CDH23 ADGRV1 PCDH15

6.19e-074188333009420
Pubmed

Large-scale profiling of Rab GTPase trafficking networks: the membrome.

RAB5A RAB5B RAB5C

1.54e-065188315944222
Pubmed

A growth factor signaling cascade confined to circular ruffles in macrophages.

RAB5A RAB5B RAB5C

1.54e-065188323213469
Pubmed

A novel binding protein composed of homophilic tetramer exhibits unique properties for the small GTPase Rab5.

RAB5A RAB5B RAB5C

1.54e-065188311733506
Pubmed

Scaffold protein harmonin (USH1C) provides molecular links between Usher syndrome type 1 and type 2.

ADGRV1 PCDH15 USH2A

1.54e-065188316301216
Pubmed

Structure and evolution of RIM-BP genes: identification of a novel family member.

RIMBP3 RIMBP3C RIMBP3B

1.54e-065188317855024
Pubmed

Nell1-deficient mice have reduced expression of extracellular matrix proteins causing cranial and vertebral defects.

COL10A1 COL11A1 DGKG TFIP11 ALX4 HOXD13 UNC5C PRKCG NOTCH1

2.35e-06210188916537572
Pubmed

RIN3: a novel Rab5 GEF interacting with amphiphysin II involved in the early endocytic pathway.

RAB5A RAB5B RAB5C

3.07e-066188312972505
Pubmed

MKRN2 Physically Interacts with GLE1 to Regulate mRNA Export and Zebrafish Retinal Development.

EPHB3 ERBB2 PSMA3 PSMA4 POLR2H TENM3 UNC5C NAT10 PHIP NOTCH1 EPHA7

4.50e-063581881132460013
Pubmed

Two quantitative trait loci affecting progressive hearing loss in 101/H mice.

CDH23 CTNNA3 PCDH15

8.53e-068188316897347
Pubmed

UMD-USHbases: a comprehensive set of databases to record and analyse pathogenic mutations and unclassified variants in seven Usher syndrome causing genes.

CDH23 PCDH15 USH2A

8.53e-068188318484607
Pubmed

Molecular basis of human Usher syndrome: deciphering the meshes of the Usher protein network provides insights into the pathomechanisms of the Usher disease.

CDH23 PCDH15 USH2A

8.53e-068188316545802
Pubmed

Interrogating the protein interactomes of RAS isoforms identifies PIP5K1A as a KRAS-specific vulnerability.

MBOAT7 ROR1 TUB STT3B JPH1 JUP NISCH NECTIN1 PTAR1 LRP6 PLXNA1 NOTCH1

1.01e-054671881230194290
Pubmed

Bhlhb5 regulates the postmitotic acquisition of area identities in layers II-V of the developing neocortex.

CRYM TENM3 PRKCG EPHA7

1.13e-0526188418957218
Pubmed

Competitive binding of E3 ligases TRIM26 and WWP2 controls SOX2 in glioblastoma.

COL11A1 PSMA4 MRPL54 JPH2 CP TFIP11 CCT2 POF1B STT3B CELSR1 SIPA1L1 A2ML1 SLC45A2 RAB5A EPHA7

1.19e-057321881534732716
Pubmed

Auditory cortex interneuron development requires cadherins operating hair-cell mechanoelectrical transduction.

CDH23 ADGRV1 PCDH15

1.27e-059188328705869
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

FNIP2 ALS2 TENM2 FEM1B TENM3 NISCH SIPA1L1 SEL1L3 CHD6 SELENOI PLCE1

1.50e-054071881112693553
Pubmed

Proteomic analysis of α4β1 integrin adhesion complexes reveals α-subunit-dependent protein recruitment.

PSMA3 MCM3 CCT2 XPO1 PPP2CA PPP2CB FCGR2C FCGR2A NAT10 PLEC SDHA RAB5C

1.66e-054911881222623428
Pubmed

Expression of signaling components in embryonic eyelid epithelium.

ERBB2 ADAM17 NOTCH1

1.81e-0510188324498290
Pubmed

Interaction cloning and characterization of the cDNA encoding the human prenylated rab acceptor (PRA1).

RAB5A RAB5B RAB5C

1.81e-0510188310329441
Pubmed

Systematic proteomics of endogenous human cohesin reveals an interaction with diverse splicing factors and RNA-binding proteins required for mitotic progression.

MSH2 XPO1 DDB1 POF1B JUP ANAPC1 NAT10 PWP2 PLEC

1.89e-05272188931010829
Pubmed

A Global Analysis of the Receptor Tyrosine Kinase-Protein Phosphatase Interactome.

ERBB2 PDGFRB PSMA3 PSMA4 ROR1 SLC3A1 PTPN6 PTPRB SLC45A2 CHD6 EPHA7

2.00e-054201881128065597
Pubmed

Ex vivo Quantitative Proteomic Analysis of Serotonin Transporter Interactome: Network Impact of the SERT Ala56 Coding Variant.

SLC25A46 CORO2A BCKDHA ADGRV1 CRMP1 SLC32A1 PPP2CB SIPA1L1 CTNNA3 RAB5A JPH3

2.48e-054301881132581705
Pubmed

Genome-wide association study of lung function decline in adults with and without asthma.

CDH23 SVEP1 PCDH15 PLXNA4

2.64e-0532188422424883
Pubmed

Notch interferes with the scaffold function of JNK-interacting protein 1 to inhibit the JNK signaling pathway.

MAPK8IP1 NOTCH1

2.91e-052188216179393
Pubmed

The protein-tyrosine phosphatase SHP-1 associates with the phosphorylated immunoreceptor tyrosine-based activation motif of Fc gamma RIIa to modulate signaling events in myeloid cells.

PTPN6 FCGR2A

2.91e-052188212832410
Pubmed

Regulation of spindle formation by active mitogen-activated protein kinase and protein phosphatase 2A during mouse oocyte meiosis.

PPP2CA PPP2CB

2.91e-052188211751260
Pubmed

Using thermal scanning assays to test protein-protein interactions of inner-ear cadherins.

CDH23 PCDH15

2.91e-052188229261728
Pubmed

ErbB2 induces Notch1 activity and function in breast cancer cells.

ERBB2 NOTCH1

2.91e-052188220443831
Pubmed

Homozygous variants in the HEXB and MBOAT7 genes underlie neurological diseases in consanguineous families.

HEXB MBOAT7

2.91e-052188231852446
Pubmed

Man to mouse--lessons learned from the distal end of the human X chromosome.

PRKX PRKY

2.91e-05218829414316
Pubmed

Profiles of PrKX expression in developmental mouse embryo and human tissues.

PRKX PRKY

2.91e-052188215879576
Pubmed

Developmental expression of potassium-channel subunit Kv3.2 within subpopulations of mouse hippocampal inhibitory interneurons.

KCNC1 KCNC2

2.91e-052188212000114
Pubmed

Allelic hierarchy of CDH23 mutations causing non-syndromic deafness DFNB12 or Usher syndrome USH1D in compound heterozygotes.

CDH23 PCDH15

2.91e-052188221940737
Pubmed

Dysregulation of the ADAM17/Notch signalling pathways in endometriosis: from oxidative stress to fibrosis.

ADAM17 NOTCH1

2.91e-052188228486700
Pubmed

A versatile single-plasmid system for tissue-specific and inducible control of gene expression in transgenic mice.

JPH2 JPH1

2.91e-052188221518849
Pubmed

Digenic inheritance of deafness caused by mutations in genes encoding cadherin 23 and protocadherin 15 in mice and humans.

CDH23 PCDH15

2.91e-052188215537665
Pubmed

Chondroitin sulfate synthase-3. Molecular cloning and characterization.

CHSY1 CHSY3

2.91e-052188212907687
Pubmed

ADAM17 regulates epidermal growth factor receptor expression through the activation of Notch1 in non-small cell lung cancer.

ADAM17 NOTCH1

2.91e-052188220551051
Pubmed

Notch-1 signalling requires ligand-induced proteolytic release of intracellular domain.

ADAM17 NOTCH1

2.91e-05218829620803
Pubmed

Deficiency of triad junction and contraction in mutant skeletal muscle lacking junctophilin type 1.

JPH2 JPH1

2.91e-052188211535622
Pubmed

Abnormal XY interchange between a novel isolated protein kinase gene, PRKY, and its homologue, PRKX, accounts for one third of all (Y+)XX males and (Y-)XY females.

PRKX PRKY

2.91e-05218829302280
Pubmed

Genetic mapping of the Rab5a and Rab5b genes on mouse Chromosomes 17 and 2, respectively.

RAB5A RAB5B

2.91e-05218828835543
Pubmed

Kv3.1-containing K(+) channels are reduced in untreated schizophrenia and normalized with antipsychotic drugs.

KCNC1 KCNC2

2.91e-052188223628987
Pubmed

FBP1 inhibits NSCLC stemness by promoting ubiquitination of Notch1 intracellular domain and accelerating degradation.

FBP1 NOTCH1

2.91e-052188238349431
Pubmed

A novel missense mutation locus of cadherin 23 and the interaction of cadherin 23 and protocadherin 15 in a patient with usher syndrome.

CDH23 PCDH15

2.91e-052188232835555
Pubmed

Characteristics of Retinitis Pigmentosa Associated with ADGRV1 and Comparison with USH2A in Patients from a Multicentric Usher Syndrome Study Treatrush.

ADGRV1 USH2A

2.91e-052188234638692
Pubmed

Interaction between HER2 and ATM predicts poor survival in bladder cancer patients.

ERBB2 ATM

2.91e-052188236056635
Pubmed

K(+) channel expression distinguishes subpopulations of parvalbumin- and somatostatin-containing neocortical interneurons.

KCNC1 KCNC2

2.91e-052188210531438
Pubmed

The role of protein phosphatase 2A catalytic subunit Calpha in embryogenesis: evidence from sequence analysis and localization studies.

PPP2CA PPP2CB

2.91e-052188210543450
Pubmed

Usher's Syndrome Type II: A Comparative Study of Genetic Mutations and Vestibular System Evaluation.

ADGRV1 USH2A

2.91e-052188228653555
Pubmed

Tyrosine phosphorylation of PP2A is regulated by HER-2 signalling and correlates with breast cancer progression.

ERBB2 PPP2CA

2.91e-052188219360341
Pubmed

Inner hair cells are not required for survival of spiral ganglion neurons in the adult cochlea.

SLC19A2 CDH23

2.91e-052188222238076
Pubmed

A unique role for Kv3 voltage-gated potassium channels in starburst amacrine cell signaling in mouse retina.

KCNC1 KCNC2

2.91e-052188215317859
Pubmed

Structural basis of SALM5-induced PTPδ dimerization for synaptic differentiation.

PTPRD LRFN5

2.91e-052188229348579
Pubmed

Structure and transcriptional regulation of protein phosphatase 2A catalytic subunit genes.

PPP2CA PPP2CB

2.91e-05218821846293
Pubmed

Identification of carboxyl-terminal MCM3 phosphorylation sites using polyreactive phosphospecific antibodies.

MCM3 ATM

2.91e-052188217244605
Pubmed

Structural basis of trans-synaptic interactions between PTPδ and SALMs for inducing synapse formation.

PTPRD LRFN5

2.91e-052188229348429
Pubmed

Notch pathway as candidate therapeutic target in Her2/Neu/ErbB2 receptor-negative breast tumors.

ERBB2 NOTCH1

2.91e-052188219956862
Pubmed

PP2A regulates kinetochore-microtubule attachment during meiosis I in oocyte.

PPP2CA PPP2CB

2.91e-052188227096707
Pubmed

Combining detection of Notch1 and tumor necrosis factor-α converting enzyme is a reliable biomarker for the diagnosis of abdominal aortic aneurysms.

ADAM17 NOTCH1

2.91e-052188225744398
Pubmed

Development and regeneration of sensory transduction in auditory hair cells requires functional interaction between cadherin-23 and protocadherin-15.

CDH23 PCDH15

2.91e-052188220739546
Pubmed

Junctophilin damage contributes to early strength deficits and EC coupling failure after eccentric contractions.

JPH2 JPH1

2.91e-052188219940065
Pubmed

Study of USH1 splicing variants through minigenes and transcript analysis from nasal epithelial cells.

CDH23 PCDH15

2.91e-052188223451239
Pubmed

The Mass1frings mutation underlies early onset hearing impairment in BUB/BnJ mice, a model for the auditory pathology of Usher syndrome IIC.

CDH23 ADGRV1

2.91e-052188215820310
Pubmed

A novel murine PKA-related protein kinase involved in neuronal differentiation.

PRKX PRKY

2.91e-052188210729225
Pubmed

The human protein kinase gene PKX1 on Xp22.3 displays Xp/Yp homology and is a site of chromosomal instability.

PRKX PRKY

2.91e-05218827633447
Pubmed

Effective phagocytosis of low Her2 tumor cell lines with engineered, aglycosylated IgG displaying high FcγRIIa affinity and selectivity.

ERBB2 FCGR2A

2.91e-052188223030766
Pubmed

Activation of SV40 DNA replication in vitro by cellular protein phosphatase 2A.

PPP2CA PPP2CB

2.91e-05218822555176
Pubmed

Partial USH2A deletions contribute to Usher syndrome in Denmark.

PCDH15 USH2A

2.91e-052188225804404
Pubmed

ATM phosphorylates PP2A subunit A resulting in nuclear export and spatiotemporal regulation of the DNA damage response.

PPP2CA ATM

2.91e-052188236434396
Pubmed

Structure of a force-conveying cadherin bond essential for inner-ear mechanotransduction.

CDH23 PCDH15

2.91e-052188223135401
Pubmed

Deficiency of triad formation in developing skeletal muscle cells lacking junctophilin type 1.

JPH2 JPH1

2.91e-052188212135771
Pubmed

A mouse model for nonsyndromic deafness (DFNB12) links hearing loss to defects in tip links of mechanosensory hair cells.

CDH23 PCDH15

2.91e-052188219270079
Pubmed

PRKX critically regulates endothelial cell proliferation, migration, and vascular-like structure formation.

PRKX PRKY

2.91e-052188221684272
Pubmed

A novel proteolytic cleavage involved in Notch signaling: the role of the disintegrin-metalloprotease TACE.

ADAM17 NOTCH1

2.91e-052188210882063
Pubmed

Wakayama Symposium: Notch-FoxL2-α-SMA axis in eyelid levator muscle development and congenital blepharophimosis.

FOXL2 NOTCH1

2.91e-052188223084143
Pubmed

Cardiomyocyte cohesion is increased after ADAM17 inhibition.

JUP ADAM17

2.91e-052188236733457
Pubmed

The adaptor protein VEPH1 interacts with the kinase domain of ERBB2 and impacts EGF signaling in ovarian cancer cells.

ERBB2 VEPH1

2.91e-052188236828346
Pubmed

ErbB-2 inhibition activates Notch-1 and sensitizes breast cancer cells to a gamma-secretase inhibitor.

ERBB2 NOTCH1

2.91e-052188218469855
Pubmed

Usherin is required for maintenance of retinal photoreceptors and normal development of cochlear hair cells.

CDH23 USH2A

2.91e-052188217360538
InteractionRSPH1 interactions

MAPK8IP1 CORO2A CRMP1 JPH1 PTPRD KDM4A PLEC SDHA JPH3

3.29e-061311849int:RSPH1
GeneFamilyFibronectin type III domain containing

EPHB3 SNED1 PTPRB PTPRD LRFN5 USH2A EPHA7

2.00e-041601357555
GeneFamilyFibronectin type III domain containing|USH2 complex

ADGRV1 USH2A

3.29e-04413521244
CoexpressionBENPORATH_PRC2_TARGETS

EPHB3 TBX21 CDH23 DGKG LHX8 FOXA2 ALX4 RIMBP3 SLC32A1 CNNM1 FBP1 FOXL2 KCNC2 HOXD13 LRFN5 UNC5C RIMBP3C ANKRD18A GRIN3A PLEC RIMBP3B

1.02e-0865018821M8448
CoexpressionMIKKELSEN_MEF_HCP_WITH_H3K27ME3

SGSM1 TBX21 CBLC FOXA2 SLC32A1 CNNM1 CELSR1 CRYM FBP1 KCNC1 LRFN5 NR2E1 SEL1L3 SCNN1B TMPRSS2 SHE FGF14 OLIG1 JPH3

5.81e-0859118819M2019
CoexpressionMIKKELSEN_MEF_HCP_WITH_H3K27ME3

SGSM1 TBX21 CBLC FOXA2 SLC32A1 CNNM1 CELSR1 CRYM FBP1 KCNC1 LRFN5 NR2E1 SEL1L3 SCNN1B TMPRSS2 SHE FGF14 OLIG1 JPH3

7.55e-0860118819MM866
CoexpressionBENPORATH_EED_TARGETS

EPHB3 TBX21 CDH23 DGKG LHX8 FOXA2 ABCA8 ALX4 RIMBP3 SLC32A1 CNNM1 FBP1 FOXL2 KCNC2 HOXD13 LRFN5 UNC5C PTAR1 NR2E1 RIMBP3C ANKRD18A GRIN3A PLEC OLIG1 RIMBP3B

1.76e-07105918825M7617
CoexpressionBENPORATH_SUZ12_TARGETS

EPHB3 TBX21 CDH23 DGKG LHX8 FOXA2 ALX4 CRMP1 RIMBP3 SLC32A1 CNNM1 FBP1 FOXL2 KCNC2 HOXD13 LRFN5 UNC5C RIMBP3C ANKRD18A GRIN3A PLEC OLIG1 RIMBP3B

1.60e-06103518823M9898
CoexpressionGSE37605_C57BL6_VS_NOD_FOXP3_FUSION_GFP_TREG_UP

COL10A1 SEMA4G JPH1 KCNC2 HOXD13 LRRC51 LRFN5 GRIN3A

3.27e-061241888M8800
CoexpressionBENPORATH_ES_WITH_H3K27ME3

EPHB3 TBX21 CDH23 DGKG LHX8 FOXA2 ALX4 CRMP1 RIMBP3 SLC32A1 CNNM1 FBP1 FOXL2 KCNC2 HOXD13 LRFN5 UNC5C NR2E1 RIMBP3C ANKRD18A GRIN3A PLEC RIMBP3B

5.51e-06111518823M10371
CoexpressionMANNO_MIDBRAIN_NEUROTYPES_HGABA

COL11A1 ATCAY GRIK2 TENM2 CRMP1 JPH1 SLC32A1 FSIP2 MGAT5 KCNC1 KCNC2 LRFN5 NECTIN1 PRKAB2 PLXNA4 SV2C CHSY3 ANKRD18A FGF14 GRIN3A PLXNA1 JPH3

1.57e-05110618822M39071
CoexpressionAtlasDevelopingKidney_e13.5_podocyte cells_emap-27773_top-relative-expression-ranked_500

CD109 MCM3 TENM2 CRMP1 SNED1 CELSR1 CRYM PTPRB KCNC2 ANAPC1 LRFN5 UNC5C SHE GRIN3A SLC25A19

6.02e-0643118515gudmap_developingKidney_e13.5_podocyte cells_500
CoexpressionAtlaskidney_P0_JuxtaGlom_Ren1_top-relative-expression-ranked_500

IQGAP2 PDGFRB ROR1 JPH2 ITGA1 ABCA8 SLC3A1 FBP1 SLC12A1 CTNNA3 SEL1L3 AOC3 TMPRSS2 TNS1 PLCE1

1.18e-0545618515gudmap_kidney_P0_JuxtaGlom_Ren1_500
CoexpressionAtlasProgenitor-Cell-Biology-Consortium_induced-Ectoderm_top-relative-expression-ranked_500

NAALAD2 COL11A1 ATCAY AOAH DGKG ADGRV1 CHI3L1 NSUN7 FSIP2 PTPRD NR2E1 TMPRSS2 TRPM8 JPH3 EPHA7

3.06e-0549518515PCBC_ECTO_500
CoexpressionAtlascervix, uterine

ENPP3 FOXA2 HOXD13 PLXNA4 SCNN1B CHSY3 FGF14 GRIN3A

4.99e-051491858cervix, uterine
CoexpressionAtlasFacebaseRNAseq_e10.5_Neural Epithelium Overlying Medial Eminence_top-relative-expression-ranked_2500_k-means-cluster#5

MAPK8IP1 IQGAP2 ATCAY FBXO11 ALS2 GRIK2 ADGRV1 TUB TENM2 CRMP1 ADAM17 NOTCH1

6.07e-0535018512Facebase_RNAseq_e10.5_Neural Epithelium Overlying Medial Eminence_2500_K5
ToppCellLPS-antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-MatrixFB|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

NAALAD2 AOX1 CHI3L1 ABCA8 SVEP1 SNED1 PTPRD TENM3 LRFN5 UNC5C PCDH15 PLXNA4

4.30e-111941881260622bd2f75bfe4c37f721cb12f03dab33f2f58d
ToppCellCOVID-19-lung-Fibroblast|lung / Disease (COVID-19 only), tissue and cell type

FKBP10 PDGFRB AOX1 ABCA8 SVEP1 SNED1 PTPRD TENM3 LRFN5 UNC5C PLXNA4 FGF14

5.46e-1119818812df3de77216f5c5d6141ec44d01c56b942f611838
ToppCellLPS-IL1RA+antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-MatrixFB|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

NAALAD2 PDGFRB AOX1 ABCA8 SVEP1 SNED1 PTPRD TENM3 UNC5C PCDH15 PLXNA4

6.77e-1019318811fb28717fadd06c3840636d25409ce80c9254bd34
ToppCellLPS-antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-Activated_MatrixFB|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

AOX1 CHI3L1 ABCA8 SVEP1 SNED1 PTPRD TENM3 LRFN5 UNC5C PCDH15 PLXNA4

7.15e-101941881189b706af2b25991fc2707eb24f49ba6ff3ae01f7
ToppCellLPS_IL1RA-Epithelial_alveolar-AT_1-Differentiating_AT1|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

EPHB3 ERBB2 ROR1 VEPH1 CP FOXA2 CELSR1 FBP1 SCNN1B TMPRSS2 PLXNA1

8.88e-1019818811b598ab958e31f1e98bd06dc0097b58ac3a3f90a3
ToppCellControl_saline-Epithelial_alveolar-AT_1-Differentiating_AT1|Control_saline / Treatment groups by lineage, cell group, cell type

EPHB3 ERBB2 ROR1 VEPH1 FOXA2 CELSR1 FBP1 SCNN1B TMPRSS2 PLXNA1 PLCE1

8.88e-101981881185f424cd9bb3117c9e322031024aabb87696ce47
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-precursor_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL11A1 GRIK2 ADGRV1 ALX4 SVEP1 CRYM SLC12A1 UNC5C TRPM8 USH2A

1.69e-0916018810c381ec6be8cf887861cc18f831a20db42f953fe1
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-pre_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL11A1 GRIK2 ADGRV1 ALX4 SVEP1 CRYM SLC12A1 UNC5C TRPM8 USH2A

1.69e-091601881025c8f3d2a6d14ff0ca0b965fce89d3ff22f40585
ToppCellCOVID-19-kidney-Podocyte|kidney / Disease (COVID-19 only), tissue and cell type

IQGAP2 PDGFRB GRIK2 CHI3L1 TENM2 MGAT5 PTPRD TENM3 UNC5C PLCE1

6.17e-0918318810fb5e2a31b560126e1c04a386c24c365901c60ad7
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

IQGAP2 PDGFRB GRIK2 CHI3L1 TENM2 MGAT5 PTPRD TENM3 UNC5C PLCE1

6.17e-0918318810612d93df03252d4d2ccdce5a9bc162cfd9172a1a
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

IQGAP2 PDGFRB GRIK2 CHI3L1 TENM2 MGAT5 PTPRD TENM3 UNC5C PLCE1

6.85e-09185188109197f074e769d54031ec41abfc65fcc0c6552c7e
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

IQGAP2 PDGFRB GRIK2 CHI3L1 TENM2 MGAT5 PTPRD TENM3 UNC5C PLCE1

6.85e-0918518810ce7d62394b09c26ca65b8cdb280afec5e25bbb62
ToppCellAdult-Epithelial-club_cell-D231|Adult / Lineage, Cell type, age group and donor

CP GRIK2 MSI1 ADGRV1 CELSR1 PTPRD SEL1L3 PLXNA4 SCNN1B EPHA7

7.60e-0918718810ee59d7d3de5879738ff0b9c3ea5e4847fb48cb86
ToppCellPCW_07-8.5-Mesenchymal-Mesenchymal_fibroblastic-mes_immature3_(17)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

NAALAD2 UPK1A PDGFRB ROR1 ITGA1 ABCA8 SVEP1 SNED1 PTPRD UNC5C

7.60e-0918718810a9316e2818217ec5feae9cf8816f7249803caee6
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

NAALAD2 PDGFRB ROR1 JPH2 ITGA1 SVEP1 TENM3 LRFN5 UNC5C CHSY3

8.85e-091901881070c86dd454afb21d4a85db56c5f369d4b342bc97
ToppCellLPS-IL1RA+antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-Activated_MatrixFB|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PDGFRB AOX1 CHI3L1 SVEP1 SNED1 PTPRD TENM3 UNC5C PCDH15 PLXNA4

9.30e-0919118810b13229bb7f3713a392271aaf5dbae3edd1b9fe5a
ToppCellLPS-antiTNF-Stromal_mesenchymal-Matrix_Fibroblast|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

AOX1 CHI3L1 ABCA8 SVEP1 SNED1 PTPRD TENM3 UNC5C PCDH15 PLXNA4

9.78e-0919218810dcd924d6eb67d33ee9f5d3e8ab6e1d4283d6b708
ToppCellLPS_only-Stromal_mesenchymal|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PDGFRB AOX1 CHI3L1 SVEP1 SNED1 PTPRD TENM3 UNC5C PCDH15 PLXNA4

9.78e-0919218810162d8b5858d150ecbbd1c9bf2b19c6c9cd50a158
ToppCellChildren_(3_yrs)-Epithelial-club_cell-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

CP GRIK2 ADGRV1 CELSR1 PTPRD SEL1L3 SCNN1B CHSY3 PLCE1 EPHA7

1.13e-0819518810dccc32fcf772e2504de7f663ef0a5bd8e23e92fc
ToppCellTracheal-10x3prime_v2-Epithelial-Epi_airway_secretory-Secretory_Club|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

ERBB2 VEPH1 FOXA2 C16orf89 JPH1 SYT15 FBP1 SEL1L3 SCNN1B PRKCG

1.19e-0819618810d5f9168001e60bafec17fe6c702e68f5528edc20
ToppCellLPS_anti-TNF-Epithelial_airway-airway_epithelial-Airway-Club|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

CP GRIK2 FOXA2 POF1B C16orf89 CELSR1 A2ML1 KIF19 SEL1L3 SCNN1B

1.31e-08198188106712216c5a7fd86b68fd45b0ff7794975f19774e
ToppCellLPS_IL1RA-Mesenchymal_fibroblastic-Fibroblasts-MatrixFB|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

FKBP10 PDGFRB CP CHI3L1 ABCA8 SVEP1 PTPRD TENM3 UNC5C PLXNA4

1.38e-0819918810a7dd94b172c973a131a6792f8ccd9bfe44d984ac
ToppCellControl_saline-Epithelial_airway-airway_epithelial-Airway-Club|Control_saline / Treatment groups by lineage, cell group, cell type

IQGAP2 CP ADGRV1 CHI3L1 POF1B C16orf89 CELSR1 A2ML1 SEL1L3 SCNN1B

1.38e-08199188105cc8b553a58669a30eb10845beb23983dcdf5a6a
ToppCellLPS_IL1RA-Epithelial_alveolar-AT_1|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

EPHB3 ERBB2 ROR1 VEPH1 CP FOXA2 CELSR1 FBP1 SCNN1B TMPRSS2

1.38e-0819918810a270630626df614f8605abddb7dee7c4d74f6149
ToppCellLPS_IL1RA_TNF-Epithelial_alveolar-AT_1-Differentiating_AT1|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

ERBB2 ROR1 VEPH1 CP FOXA2 CELSR1 FBP1 SCNN1B TMPRSS2 PLXNA1

1.44e-0820018810ddfb1f006365bf16203ee49f20200f68220cc288
ToppCellLPS_anti-TNF-Epithelial_alveolar-AT_1|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

ERBB2 ROR1 VEPH1 CP ADGRV1 FOXA2 CELSR1 FBP1 SCNN1B TMPRSS2

1.44e-08200188108683445ad5b70748c4a1f12eb77d47623085147e
ToppCellNeuronal-Inhibitory-iB-iB_3(PVALB-SST)|Neuronal / cells hierarchy compared to all cells using T-Statistic

GRIK2 ITGA1 SLC32A1 TENM3 KCNC2 PCDH15 GRIN3A TTC38 PRKX PLCE1

1.44e-0820018810107854f4855fc99c9f7e737eb246f0d868e6c5fd
ToppCellTracheal-NucSeq-Stromal|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

COL11A1 PDGFRB AOX1 ABCA8 SVEP1 SNED1 TENM3 LRFN5 FGF14 TNS1

1.44e-0820018810c318d14bd6fd6f42c597eb55ac9e2f48008aeb9b
ToppCellfacs-Lung-24m-Epithelial-airway_epithelial-club_cell-club_cell|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

UPK1A CBLC CHI3L1 SEMA4G NEK2 FBP1 TMPRSS2 OLIG1 OSGIN1

4.98e-0817118898ed98f223143bd81d9819e9a420eb9cc81ee6c53
ToppCellfacs-Lung-24m-Epithelial-airway_epithelial-club_cell|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

UPK1A CBLC CHI3L1 SEMA4G NEK2 FBP1 TMPRSS2 OLIG1 OSGIN1

4.98e-081711889bd339e482f09a3fa04b086029b94f45205b8a6c5
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

IQGAP2 GRIK2 CHI3L1 TENM2 MGAT5 PTPRD TENM3 UNC5C PLCE1

7.38e-0817918897394e77e665bf16d3733df91bb12907be460ab44
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

IQGAP2 PDGFRB GRIK2 CHI3L1 TENM2 MGAT5 PTPRD UNC5C PLCE1

8.91e-0818318893c516fe5083f02bad1f464ed284010b4131a833c
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

IQGAP2 GRIK2 CHI3L1 TENM2 MGAT5 PTPRD TENM3 UNC5C PLCE1

8.91e-081831889eb559ae3ae252d9365c24ef557dd49b78ed6d898
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

IQGAP2 PDGFRB GRIK2 CHI3L1 TENM2 MGAT5 PTPRD UNC5C PLCE1

8.91e-0818318899c2689d76fc6d30f5ab093428aa669d0a98953cf
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-kidney_interstitial_fibroblast_5|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

NAALAD2 PDGFRB ITGA1 ABCA8 SVEP1 TENM3 LRFN5 UNC5C CHSY3

9.34e-081841889c5436a8e45f471b8d1301abbe9c7879204537f52
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Renal_corpuscle_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

IQGAP2 PDGFRB GRIK2 CHI3L1 TENM2 MGAT5 PTPRD UNC5C PLCE1

9.34e-0818418897294b379ce4cb8fa75e432559082f93cd106aaf5
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

IQGAP2 PDGFRB GRIK2 CHI3L1 TENM2 MGAT5 TENM3 UNC5C PLCE1

9.78e-081851889b848b63aff4d9dbb9e66a85876d4c7c6dacd0579
ToppCellLPS-antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-Diff_MatrixFB|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

AOX1 CHI3L1 SVEP1 SNED1 PTPRD TENM3 UNC5C PCDH15 PLXNA4

1.17e-071891889a153b83314cf52808f685296cff8c95af3f4983d
ToppCellLPS_only-Stromal_mesenchymal-Matrix_Fibroblast-MatrixFB|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PDGFRB AOX1 ABCA8 SVEP1 SNED1 PTPRD UNC5C PCDH15 PLXNA4

1.17e-0718918892a22b9fae70afb3dab8476f9c00e48a4df756410
ToppCellLPS-IL1RA-Stromal_mesenchymal-Matrix_Fibroblast-Activated_MatrixFB|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PDGFRB AOX1 CHI3L1 SVEP1 PTPRD TENM3 UNC5C PCDH15 PLXNA4

1.23e-07190188945df8fee00f8949937863159d7aa042e72748d9b
ToppCellControl-Fibroblasts|Control / group, cell type (main and fine annotations)

AOX1 ITGA1 ABCA8 SVEP1 TENM3 LRFN5 UNC5C PCDH15 FGF14

1.23e-0719018893a42a9b98d954685d38a741f44545898d0e3e9ce
ToppCellLPS-IL1RA+antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-Diff_MatrixFB|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

NAALAD2 PDGFRB AOX1 CHI3L1 SVEP1 PTPRD UNC5C PCDH15 PLXNA4

1.23e-071901889841cd55861b43578d704418b9bc0af2e8b88323a
ToppCellAdult-Epithelial-club_cell|Adult / Lineage, Cell type, age group and donor

CP GRIK2 ADGRV1 CELSR1 PTPRD SEL1L3 PLXNA4 SCNN1B EPHA7

1.23e-071901889756bff697d30aec56c0ebfca94295f084a15bf37
ToppCellLPS_only-Stromal_mesenchymal-Matrix_Fibroblast-Diff_MatrixFB|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PDGFRB AOX1 CHI3L1 SVEP1 SNED1 PTPRD UNC5C PCDH15 PLXNA4

1.23e-071901889d60395739458d7f47a3350ade751fe3819500320
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

NAALAD2 PDGFRB ROR1 ITGA1 ABCA8 SVEP1 TENM3 LRFN5 CHSY3

1.28e-07191188939092a0aff8097617820c59f5fea9ee2bb4f63a2
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

NAALAD2 PDGFRB ITGA1 ABCA8 SVEP1 TENM3 LRFN5 UNC5C CHSY3

1.28e-071911889107113b930d9ad171f1b2aa20df4567c94fae7d8
ToppCellnucseq-Mesenchymal-Fibroblastic-Fibroblastic_2-AF1|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

AOX1 ITGA1 ABCA8 SVEP1 TENM3 LRFN5 UNC5C PCDH15 FGF14

1.28e-0719118896688cee34beee4f151ac17fccbc9c26a9aad72e1
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

NAALAD2 PDGFRB ROR1 ITGA1 ABCA8 SVEP1 TENM3 LRFN5 CHSY3

1.28e-071911889ee5f1b1c59029c46cbb1a00935c03b9317bb9da9
ToppCellChildren_(3_yrs)-Epithelial-club_cell|Children_(3_yrs) / Lineage, Cell type, age group and donor

CP GRIK2 ADGRV1 CELSR1 PTPRD SEL1L3 SCNN1B CHSY3 EPHA7

1.28e-07191188923776c7302cead3881b39127398f3b3e0d27885e
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

NAALAD2 PDGFRB ITGA1 ABCA8 SVEP1 TENM3 LRFN5 UNC5C CHSY3

1.28e-071911889bc353a79a1d11ca52bba5e3874a80d432e1a7715
ToppCellLPS-IL1RA+antiTNF-Stromal_mesenchymal|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PDGFRB AOX1 CHI3L1 SVEP1 PTPRD TENM3 UNC5C PCDH15 PLXNA4

1.34e-0719218893d0cb19f037f604253d7d728689aeaa94251e92b
ToppCellLPS_only-Stromal_mesenchymal-Matrix_Fibroblast|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PDGFRB AOX1 CHI3L1 SVEP1 PTPRD TENM3 UNC5C PCDH15 PLXNA4

1.34e-071921889ee085e04d5dcfb657522484ed20b8c1ddeccfe0c
ToppCellLPS-IL1RA+antiTNF-Stromal_mesenchymal-Matrix_Fibroblast|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PDGFRB AOX1 CHI3L1 SVEP1 PTPRD TENM3 UNC5C PCDH15 PLXNA4

1.34e-0719218896f4ef24dab544681304b7f8a9dc073e7edaa4cf5
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_3|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ROR1 SLC32A1 TENM3 KCNC1 KCNC2 PCDH15 GRIN3A PRKX PLCE1

1.40e-07193188953bcd50892c379b2a571751f6eb1062436339fe7
ToppCellMesenchymal-matrix_fibroblast_1_cell|World / Lineage, Cell type, age group and donor

ITGA1 TENM2 ABCA8 SVEP1 SNED1 PTPRD LRFN5 UNC5C PCDH15

1.40e-071931889acad568621ed677031797b8c2e34dafea798d681
ToppCellLPS-antiTNF-Stromal_mesenchymal|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PDGFRB CHI3L1 SVEP1 SNED1 PTPRD TENM3 UNC5C PCDH15 PLXNA4

1.47e-0719418896e13549f697f7478b34fe71f7dd9d63c5d3db22e
ToppCellnucseq-Epithelial-Epithelial_Alveolar-Secretory/RAS-RAS|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

CP GRIK2 MSI1 C16orf89 JUP CELSR1 PTPRD SEL1L3 SCNN1B

1.47e-071941889a58841b34efe673671a9a059238e044a7254b279
ToppCellFetal_29-31_weeks-Mesenchymal-matrix_fibroblast_1_cell|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

ITGA1 TENM2 ABCA8 SVEP1 SNED1 LRFN5 UNC5C AOC3 PCDH15

1.47e-071941889011e14d9ed1393275f892060e7708ffadcd0767f
ToppCellnucseq-Epithelial-Epithelial_Alveolar-Secretory/RAS|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

CP GRIK2 MSI1 C16orf89 JUP CELSR1 PTPRD SEL1L3 SCNN1B

1.47e-0719418890cd4363627acd419e00d6d32f6dce10430aa6487
ToppCellPCW_07-8.5-Mesenchymal|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

NAALAD2 PDGFRB ROR1 ITGA1 ABCA8 SVEP1 PTPRD TENM3 UNC5C

1.60e-0719618898e10802f52e5e1853ea4ad34bf9a32a34e6112b5
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

GRIK2 SEMA4G SLC32A1 TENM3 KCNC2 PCDH15 GRIN3A PRKX PLCE1

1.60e-0719618897af6c5147ac859353504d19727dbe24f63a29dd4
ToppCellControl_saline-Epithelial_alveolar-AT_2-Differentiating_AT2|Control_saline / Treatment groups by lineage, cell group, cell type

EPHB3 VEPH1 CP ADGRV1 FOXA2 C16orf89 CELSR1 TMPRSS2 PHIP

1.67e-07197188944a59dfb889577b3160a5b13ada1276771a00241
ToppCellCOVID-19-Fibroblasts|COVID-19 / group, cell type (main and fine annotations)

FKBP10 PDGFRB ROR1 ABCA8 SVEP1 SNED1 TENM3 UNC5C FGF14

1.67e-071971889fb847f2277609c31fffcdf49517243ce0684facf
ToppCellLPS_IL1RA-Epithelial_alveolar-AT_1-AT1|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

ROR1 VEPH1 ACAD10 FOXA2 ZDHHC12 FBP1 SCNN1B TMPRSS2 SLC25A19

1.74e-0719818895a85c286f79cde5811d2595a3397c6fb7685adee
ToppCellParenchymal-NucSeq-Epithelial-Epi_airway_secretory-Secretory_Club|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

CP GRIK2 ADGRV1 CELSR1 PTPRD SEL1L3 SCNN1B CHSY3 EPHA7

1.74e-0719818891408e02e053ad3406229bfe8189da03be6366e81
ToppCellControl_saline-Epithelial_alveolar-AT_1|Control_saline / Treatment groups by lineage, cell group, cell type

ERBB2 ROR1 VEPH1 FOXA2 FBP1 SCNN1B TMPRSS2 PLXNA1 PLCE1

1.74e-0719818899b161285df7a4e51618f3517cfc5b8221ba55786
ToppCellFetal_29-31_weeks-Mesenchymal|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

FKBP10 PDGFRB ITGA1 ABCA8 SVEP1 SNED1 TENM3 LRFN5 UNC5C

1.74e-07198188921cf4d81386761d09d0f6829c01c198e5524176d
ToppCellCOVID-19-lung-Fibroblast|COVID-19 / Disease (COVID-19 only), tissue and cell type

FKBP10 PDGFRB CDH23 SVEP1 SNED1 TENM3 LRFN5 UNC5C FGF14

1.74e-0719818893ec01a55ade5e1627258cc3cfebb2c3207a4cb43
ToppCellFetal_29-31_weeks-Epithelial-club_cell|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

FNIP2 CP GRIK2 ADGRV1 C16orf89 CELSR1 PTPRD SEL1L3 SCNN1B

1.74e-0719818895fc25b008a4d8d6bec83923a16f64dd9e1ff1f2d
ToppCellNon-neuronal-Dividing-IPC-IPC-new|World / Primary Cells by Cluster

FKBP10 COL11A1 VEPH1 MCM3 MSI1 ADGRV1 NR2E1 PHIP NOTCH1

1.74e-07198188911d2d4d179bc31ef2897d7ceeaf9bed1b20cbdc0
ToppCellNon-neuronal-Dividing-IPC-IPC-new-9|World / Primary Cells by Cluster

FKBP10 COL11A1 VEPH1 MCM3 MSI1 ADGRV1 NR2E1 PHIP NOTCH1

1.74e-071981889c724ef958e14e17a7d8c02b9f842510c0780f635
ToppCellnucseq-Mesenchymal|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

PDGFRB AOX1 ITGA1 ABCA8 SVEP1 LRFN5 UNC5C PCDH15 FGF14

1.74e-0719818898f52243ca8b9ba68a75ae411506a3a6de258eb97
ToppCellLPS_IL1RA-Mesenchymal_fibroblastic-Fibroblasts-Activated_MatrixFB|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

PDGFRB AOX1 CHI3L1 SVEP1 PTPRD TENM3 PCDH15 PLXNA4 LRP6

1.82e-0719918898b86c69aaf60feff53aa782559cfece7342a23de
ToppCellMesenchymal|World / Lineage, Cell type, age group and donor

FKBP10 PDGFRB ITGA1 ABCA8 SVEP1 SNED1 TENM3 LRFN5 UNC5C

1.82e-0719918894bac110c2b3609f6ee5d0e3275da0824a6240270
ToppCellLPS_anti-TNF-Epithelial_alveolar-AT_1-Differentiating_AT1|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

ERBB2 ROR1 VEPH1 FOXA2 CELSR1 FBP1 SCNN1B TMPRSS2 PLXNA1

1.82e-071991889d43c605a4ff221cf78d91678c15d2ad20f831c7f
ToppCellLPS_IL1RA_TNF-Epithelial_alveolar-AT_1|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

ERBB2 ROR1 VEPH1 CP FOXA2 CELSR1 FBP1 SCNN1B TMPRSS2

1.82e-0719918891c70e7d6bd25980e1b92aa1cac3f3c95d9651b4b
ToppCellPCW_10-12-Mesenchymal|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

NAALAD2 PDGFRB ROR1 ITGA1 ABCA8 SVEP1 SNED1 PTPRD UNC5C

1.82e-071991889a09292de4c4447b8eee55d401808e43b817321cc
ToppCellTracheal-NucSeq-Stromal-Fibroblastic-Fibro_perichondrial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

COL11A1 PDGFRB VEPH1 CHI3L1 SVEP1 SNED1 PTPRD TENM3 LRFN5

1.90e-072001889a4ec0e80f5422b91b85264a9bb74568dd577e285
ToppCellParenchymal-NucSeq-Stromal|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

PDGFRB AOX1 ITGA1 ABCA8 SVEP1 TENM3 LRFN5 UNC5C FGF14

1.90e-072001889cf433f9b43d7db07acaf70e060f8f77c974e72f3
ToppCellLPS_only-Epithelial_alveolar-AT_1-Differentiating_AT1|LPS_only / Treatment groups by lineage, cell group, cell type

EPHB3 ERBB2 ROR1 VEPH1 CP FOXA2 FBP1 TMPRSS2 PLXNA1

1.90e-0720018892dadf317a42a7e27cc1fac74f91b806c93a57108
ToppCellParenchymal-NucSeq-Stromal-Fibroblastic|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

PDGFRB AOX1 ABCA8 SVEP1 TENM3 LRFN5 UNC5C PCDH15 FGF14

1.90e-072001889311fab076f2ceb258e3970eb21e39344b894042a
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

EEF1AKMT4-ECE2 COL11A1 UPK1A TENM3 LRFN5 UNC5C TRPM8 PLCE1

3.42e-071561888abf9dd075b1ca8f613c660cc82f8a5af071fb6ab
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell-Parietal_Epithelial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

EEF1AKMT4-ECE2 COL11A1 UPK1A TENM3 LRFN5 UNC5C TRPM8 PLCE1

3.42e-071561888dd41ed918b07fa248da458a629b3c53cb7ea8764
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen-high_Fibroblast-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

FKBP10 NAALAD2 PDGFRB ITGA1 ABCA8 SVEP1 TENM3 LRFN5

3.96e-071591888e812cbde59188924c6277c3feadf1a9592fa62a4
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen-high_Fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

FKBP10 NAALAD2 PDGFRB ITGA1 ABCA8 SVEP1 TENM3 LRFN5

3.96e-0715918882607b562903228274fbd96168ba826782fab0b53
ToppCellfacs-Brain_Non-Myeloid-Striatum-24m-Neuronal-SPN_Neuron_STR|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IQGAP2 GRIK2 TENM2 CNNM1 CRYM TENM3 LRFN5 CHSY3

6.02e-071681888b87fc63f9e35dfcfc46cb129ea569e73c5e018bb
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

IQGAP2 GRIK2 CHI3L1 TENM2 MGAT5 PTPRD UNC5C PLCE1

6.02e-071681888e96859dbf51cf8c4def8ee8db132f4d874fb4381
ToppCellfacs-Brain_Non-Myeloid-Striatum-24m-Neuronal-medium_spiny_neuron|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IQGAP2 GRIK2 TENM2 CNNM1 CRYM TENM3 LRFN5 CHSY3

6.02e-071681888b96a48552f4236a95bbcdce2f1b05041086d7101
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

IQGAP2 GRIK2 CHI3L1 TENM2 PTPRD TENM3 UNC5C PLCE1

6.02e-071681888315ca578c945aeeb77acda2727f3e6db8b43f43e
ToppCellfacs-Diaphragm-Limb_Muscle-24m|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

UPK1A VEPH1 ADGRV1 PCDH15 PLXNA4 TRPM8 ALAS2 USH2A

6.29e-07169188812bdc709bc000d7f9061ecd9fbd57233eaacb7e2
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

IQGAP2 PDGFRB CHI3L1 TENM2 PTPRD TENM3 UNC5C PLCE1

7.19e-0717218886c17a1e586a72d1bd80c20c06370429c61dc9f85
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

IQGAP2 PDGFRB CHI3L1 TENM2 MGAT5 PTPRD UNC5C PLCE1

7.85e-071741888dbdcdec08f1fc69fcdb5d8a6d78df8ef9c374d89
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

EEF1AKMT4-ECE2 PDGFRB ROR1 JPH2 DGKG UNC5C CTNNA3 PLCE1

8.19e-071751888d52794426f2703a80e91ae0a8ff2d8e0ce4aa4a8
ToppCellCOVID-19-kidney-Podocyte|COVID-19 / Disease (COVID-19 only), tissue and cell type

IQGAP2 GRIK2 CHI3L1 TENM2 PTPRD TENM3 UNC5C PLCE1

8.19e-071751888a73e3a65fd5c1e09cb0c2dae20c1a7bfcae49223
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

EEF1AKMT4-ECE2 PDGFRB ROR1 JPH2 DGKG UNC5C CTNNA3 PLCE1

8.19e-071751888454f03e6109d65f5db08dbb41ecc19ffb6bbc4e0
ToppCellFetal_29-31_weeks-Epithelial-club_cell-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

CP GRIK2 ADGRV1 CELSR1 CRYM SEL1L3 SCNN1B TMPRSS2

8.55e-0717618883bbac5c2397535631fce8fa98f6ddb4fe0260351
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

IQGAP2 GRIK2 CHI3L1 TENM2 MGAT5 PTPRD UNC5C PLCE1

8.92e-0717718884d2cdb57b427a42085c5f9affa0967b15e84dec3
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

IQGAP2 GRIK2 CHI3L1 TENM2 MGAT5 PTPRD UNC5C PLCE1

9.31e-071781888edc7143dc9959d36057cb9471681a23afcbc8cce
ToppCellAdult-Epithelial-club_cell-D122|Adult / Lineage, Cell type, age group and donor

CP GRIK2 CELSR1 CRYM PTPRD SCNN1B PLCE1 EPHA7

9.31e-07178188835a2e3ba98b6f857dbb79cf8ddb4846ddcda6c17
ToppCellCOVID-19-kidney-Epi_(Mes)|kidney / Disease (COVID-19 only), tissue and cell type

PDGFRB JPH2 CP ITGA1 TENM3 LRFN5 UNC5C PLCE1

9.71e-071791888e7c9dc63f03d3f3746b51a7e3c8393089e2ceb7d
ComputationalGenes in the cancer module 80.

EPHB3 ERBB2 PDGFRB ROR1 EPHA7

1.89e-05321135MODULE_80
ComputationalGenes in the cancer module 51.

EPHB3 ERBB2 PDGFRB ROR1 EPHA7

3.41e-05361135MODULE_51
Diseaselung non-small cell carcinoma (is_implicated_in)

FBXO11 MSH2 XPO1 PTPRB FOXL2 ATM SDHA

2.60e-051391827DOID:3908 (is_implicated_in)
DiseaseUsher syndrome, type 1D

CDH23 PCDH15

3.78e-0521822C2931208
DiseaseUSHER SYNDROME, TYPE ID

CDH23 PCDH15

3.78e-0521822C1832845
DiseaseUSHER SYNDROME, TYPE ID

CDH23 PCDH15

3.78e-0521822601067
DiseaseUsher syndrome type 1D

CDH23 PCDH15

3.78e-0521822cv:C1832845
DiseaseUsher syndrome type 1D (is_implicated_in)

CDH23 PCDH15

3.78e-0521822DOID:0110831 (is_implicated_in)
Diseasecarcinoma (implicated_via_orthology)

ERBB2 JUP RAB5A RAB5B RAB5C

4.80e-05641825DOID:305 (implicated_via_orthology)
Diseasefibrinogen measurement

COL11A1 GRIK2 ACAD10 PLEC PHIP RAB5C

6.07e-051091826EFO_0004623
Diseasecardiomyopathy (implicated_via_orthology)

ERBB2 JPH2 JPH1 SDHA JPH3

7.91e-05711825DOID:0050700 (implicated_via_orthology)
Diseasepack-years measurement

PSMA4 TENM2

1.13e-0431822EFO_0006526
Diseaserenal cell carcinoma (is_marker_for)

ERBB2 VWF PDGFRB AMACR MSH2 JUP

1.48e-041281826DOID:4450 (is_marker_for)
Diseasebone mineral content measurement

EPHB3 BMS1 ADGRV1 JUP PTPRD TNS1

1.61e-041301826EFO_0007621
Diseaselaryngeal squamous cell carcinoma (is_marker_for)

ERBB2 MSH2 FOXL2

2.08e-04191823DOID:2876 (is_marker_for)
Diseasecortical surface area measurement

FNIP2 HEXB COL11A1 SAMD9 IQGAP2 UPK1A ENPP3 ROR1 ADGRV1 XPO1 TENM2 ALX4 SVEP1 CELSR1 FBP1 UNC5C OLIG1 TNS1 PLCE1 EPHA7

2.56e-04134518220EFO_0010736
Diseasecancer (implicated_via_orthology)

MSH2 NEK2 JUP ATM RAB5A RAB5B NOTCH1 RAB5C

2.74e-042681828DOID:162 (implicated_via_orthology)
DiseaseAdenocarcinoma of large intestine

ERBB2 ROR1 MSH2 ATM EPHA7

3.28e-04961825C1319315
Diseaseserum albumin measurement

GRIK2 ITGA1 ADGRV1 ABCA8 SVEP1 NSUN7 TBC1D13 FCGR2C FCGR2A PLEC RAB5C OSGIN1

3.30e-0459218212EFO_0004535
Diseasehearing impairment

CDH23 ADGRV1 CRYM PCDH15 USH2A

3.61e-04981825C1384666
DiseaseUsher syndrome, type 1A

CDH23 PCDH15

3.74e-0451822C2931205
DiseaseUsher Syndrome, Type II

PCDH15 USH2A

3.74e-0451822C1568249
DiseaseUSHER SYNDROME, TYPE IB (disorder)

CDH23 PCDH15

3.74e-0451822C1848638
DiseaseUSHER SYNDROME, TYPE IA, FORMERLY

CDH23 PCDH15

3.74e-0451822C1848639
DiseaseUSHER SYNDROME, TYPE I, FRENCH VARIETY, FORMERLY

CDH23 PCDH15

3.74e-0451822C1848640
DiseaseUsher syndrome type 1

CDH23 PCDH15

3.74e-0451822cv:C1568247
DiseaseMalignant neoplasm of breast

ERBB2 COL11A1 VWF ROR1 CD109 DGKG GRIK2 MSI1 OSTC PTPRD NISCH SIPA1L1 SCNN1B TMEM39A ATM TNS1 NOTCH1

3.75e-04107418217C0006142
Diseasestomach carcinoma (is_marker_for)

ERBB2 XPO1 KDM4A

4.25e-04241823DOID:5517 (is_marker_for)
Diseaselate-onset Alzheimers disease

IQGAP2 AOX1 GRIK2 ABCA8 USP32 ADAM17 ATM JPH3

4.84e-042921828EFO_1001870
DiseaseUsher Syndrome, Type I

CDH23 PCDH15

5.58e-0461822C1568247
DiseaseAplasia Cutis Congenita

BMS1 PLEC

5.58e-0461822C0282160
DiseaseCiliopathies

CDH23 ADGRV1 PCDH15 SCNN1B USH2A

6.13e-041101825C4277690
Diseasehearing threshold measurement

SGSM1 SLC32A1 SV2C

6.75e-04281823EFO_0007618
Diseasebreast carcinoma (is_marker_for)

PDGFRB AMACR MSH2 ATM

7.49e-04661824DOID:3459 (is_marker_for)
DiseaseDrug habituation

GRIK2 TENM2 CTNNA3 PCDH15 SLC45A2

7.50e-041151825C0013170
DiseaseDrug abuse

GRIK2 TENM2 CTNNA3 PCDH15 SLC45A2

7.50e-041151825C0013146
DiseasePrescription Drug Abuse

GRIK2 TENM2 CTNNA3 PCDH15 SLC45A2

7.50e-041151825C4316881
DiseaseSubstance-Related Disorders

GRIK2 TENM2 CTNNA3 PCDH15 SLC45A2

7.50e-041151825C0236969
DiseaseDrug Use Disorders

GRIK2 TENM2 CTNNA3 PCDH15 SLC45A2

7.50e-041151825C0013222
DiseaseDrug Dependence

GRIK2 TENM2 CTNNA3 PCDH15 SLC45A2

7.50e-041151825C1510472
DiseaseSubstance Dependence

GRIK2 TENM2 CTNNA3 PCDH15 SLC45A2

7.50e-041151825C0038580
DiseaseSubstance Use Disorders

GRIK2 TENM2 CTNNA3 PCDH15 SLC45A2

7.50e-041151825C0038586
DiseaseOrganic Mental Disorders, Substance-Induced

GRIK2 TENM2 CTNNA3 PCDH15 SLC45A2

7.50e-041151825C0029231
DiseaseHereditary retinal dystrophy

CDH23 PCDH15

7.79e-0471822C0154860
DiseaseUsher syndrome

CDH23 PCDH15

7.79e-0471822cv:C0271097
DiseasePremature ovarian failure

POF1B FOXL2

7.79e-0471822cv:C0085215
DiseaseSubstance abuse problem

GRIK2 TENM2 CTNNA3 PCDH15 SLC45A2

7.80e-041161825C0740858
Diseasebipolar disorder, body mass index

CDH23 DGKG MAP2K5 JPH3

1.04e-03721824EFO_0004340, MONDO_0004985
Diseasemelanoma

ADGRV1 JUP SLC45A2 TRPM8 ATM

1.13e-031261825EFO_0000756
DiseaseSchizophrenia

PDGFRB AMACR CP GRIK2 CHI3L1 CRMP1 PTPN6 FBP1 AGA UNC5C NR2E1 ATM GRIN3A SDHA

1.22e-0388318214C0036341
Diseaseendometrial cancer (is_marker_for)

CHI3L1 JUP NOTCH1

1.31e-03351823DOID:1380 (is_marker_for)
Diseasemalaria (implicated_via_orthology)

FCGR2C FCGR2A

1.32e-0391822DOID:12365 (implicated_via_orthology)
Diseaseoctanoylcarnitine measurement

FNIP2 LHX8

1.32e-0391822EFO_0021042
DiseasePulmonary Cystic Fibrosis

FCGR2A SCNN1B

1.32e-0391822C0392164
DiseaseFibrocystic Disease of Pancreas

FCGR2A SCNN1B

1.32e-0391822C1527396
Diseasecolorectal carcinoma (is_marker_for)

XPO1 CHI3L1 PTPRB

1.54e-03371823DOID:0080199 (is_marker_for)
Diseasealcohol drinking

ROR1 LRFN5 PLXNA4 TRPM8

1.61e-03811824EFO_0004329
DiseaseNonsyndromic Deafness

ROR1 CDH23 ADGRV1 PCDH15

1.61e-03811824C3711374
Diseasecigarettes per day measurement

ENPP3 PSMA4 HGSNAT DGKG TENM2 PTPRD KCNC2 SIPA1L1 UNC5C

1.67e-034381829EFO_0006525
DiseaseColorectal Neoplasms

AMACR CD109 MSH2 ABCA8 FOXL2 PTPRD JPH3

1.73e-032771827C0009404
DiseaseInherited neuropathies

PRKCG FGF14 ATM

1.93e-03401823C0598589
Diseasegastric adenocarcinoma (is_implicated_in)

XPO1 PLCE1

2.01e-03111822DOID:3717 (is_implicated_in)
Diseaseosteosarcoma (is_marker_for)

MSH2 PTPRB

2.01e-03111822DOID:3347 (is_marker_for)
DiseaseCystic Fibrosis

FCGR2A SCNN1B

2.01e-03111822C0010674
DiseaseDisorder of eye

COL11A1 CDH23 ADGRV1 PCDH15 SLC45A2 USH2A

2.09e-032121826C0015397
DiseaseGlioma

ERBB2 MSH2 CHI3L1 ATM

2.09e-03871824C0017638
DiseaseTumoral calcinosis

PDGFRB PTPN6 NOTCH1

2.22e-03421823C0263628
DiseaseCalcinosis

PDGFRB PTPN6 NOTCH1

2.22e-03421823C0006663
DiseaseMicrocalcification

PDGFRB PTPN6 NOTCH1

2.22e-03421823C0521174
Diseaseglioblastoma (is_marker_for)

CHI3L1 PTPRB KCNC2

2.54e-03441823DOID:3068 (is_marker_for)
DiseaseColonic Neoplasms

ERBB2 CP GRIK2 FBP1 NOTCH1

2.58e-031521825C0009375
Diseasephosphocreatine measurement

TENM2 MGAT5

2.82e-03131822EFO_0010521
DiseaseSjogren's Syndrome

FCGR2A PHIP

2.82e-03131822C1527336
DiseaseSicca Syndrome

FCGR2A PHIP

2.82e-03131822C0086981
Diseaseprostate cancer (is_marker_for)

MSH2 PPP2CA JUP KDM4A MAP2K5

2.88e-031561825DOID:10283 (is_marker_for)
Diseasemultiple sclerosis symptom measurement

RGS13 USP32 EPHA7

2.88e-03461823EFO_0803536
Diseaseunipolar depression, information processing speed, cognitive function measurement

SLC25A46 PTAR1 PCDH15

3.07e-03471823EFO_0003761, EFO_0004363, EFO_0008354
DiseaseCardiomyopathy

JPH2 JUP SDHA

3.07e-03471823cv:C0878544
DiseaseMalignant tumor of colon

ERBB2 CP GRIK2 FBP1 NOTCH1

3.13e-031591825C0007102
Diseaselung adenocarcinoma (is_implicated_in)

ERBB2 MSH2 ALX4

3.45e-03491823DOID:3910 (is_implicated_in)
Diseaseopioid dependence

EPHB3 ADGRV1 MGAT5 KCNC2 CTNNA3 PCDH15

3.62e-032371826EFO_0005611
DiseaseNeoplasm of uncertain or unknown behavior of bladder

ATM NOTCH1

3.77e-03151822C0496930
DiseaseBenign neoplasm of bladder

ATM NOTCH1

3.77e-03151822C0154017
DiseaseCarcinoma in situ of bladder

ATM NOTCH1

3.77e-03151822C0154091
DiseaseRetinitis Pigmentosa

HGSNAT TUB NEK2 USH2A

3.99e-031041824C0035334
Diseaselung non-small cell carcinoma (is_marker_for)

MSH2 CHI3L1 FOXA2 PTPRB ATM

4.05e-031691825DOID:3908 (is_marker_for)
Diseasesmoking cessation

FNIP2 PSMA4 VEPH1 TENM2 KCNC2 PCDH15 RAB5B

4.18e-033251827EFO_0004319
DiseaseTremor, Rubral

CP UROC1

4.29e-03161822C0750940
DiseaseAtaxia, Appendicular

CP UROC1

4.29e-03161822C0750937
DiseaseAtaxia, Motor

CP UROC1

4.29e-03161822C0278161
DiseaseAtaxia, Sensory

CP UROC1

4.29e-03161822C0240991
DiseaseAlpha ketoglutarate measurement

SAMD9 TENM3

4.29e-03161822EFO_0010457
DiseaseAbnormal coordination

CP UROC1

4.29e-03161822C0520966
DiseaseMalignant lymphoma, lymphocytic, intermediate differentiation, diffuse

ATM NOTCH1

4.29e-03161822C0334634
DiseaseAtaxia, Truncal

CP UROC1

4.29e-03161822C0427190
DiseaseColorectal Carcinoma

AMACR CD109 MSH2 ABCA8 FOXL2 PTPRD SCNN1B PHIP RAB5C JPH3 EPHA7

4.38e-0370218211C0009402
Diseaseurinary bladder cancer (is_marker_for)

ERBB2 MSH2 JUP KDM4A

4.41e-031071824DOID:11054 (is_marker_for)
DiseaseRheumatoid Arthritis

CP REL MMEL1 FCGR2A HOXD13

4.58e-031741825C0003873
Diseasetreatment-resistant hypertension

COL11A1 ENPP3 MGAT5 PTPRD

4.71e-031091824EFO_1002006
DiseaseBenign neoplasm of stomach

ERBB2 ATM

4.84e-03171822C0153943
DiseaseNeoplasm of uncertain or unknown behavior of stomach

ERBB2 ATM

4.84e-03171822C0496905
DiseaseCarcinoma in situ of stomach

ERBB2 ATM

4.84e-03171822C0154060

Protein segments in the cluster

PeptideGeneStartEntry
YRPDVGYVQGMSFIA

TBC1D12

581

O60347
AMDAYYSPVSQSREG

ALX4

16

Q9H161
AYVMAGVGSPYVSRL

ERBB2

771

P04626
IGYAYPTRDIFMENI

C16orf89

241

Q6UX73
EIQNYGEIPEMSVSY

CAGE1

236

Q8TC20
LSSMDQEYAGPGYDI

ANKRD18A

16

Q8IVF6
PGYMAFLTYDEVQER

CBLC

236

Q9ULV8
EDGYGEYRIPNKAMN

ALS2

1081

Q96Q42
TLTMPNGDYIEGYFS

ALS2

1236

Q96Q42
NMLDGGAPFYTTYRT

AMACR

211

Q9UHK6
VQTVVGMLYNPFSGY

COQ3

301

Q9NZJ6
YETADGGYMTLNPRA

FCGR2A

281

P12318
YTPGQQVYFRIVTMD

A2ML1

131

A8K2U0
DDPYGTVAFAQMVYR

ADGRV1

2346

Q8WXG9
TQLGIPAAEEYFRMY

ACAD10

521

Q6JQN1
PGPYGQEMYAFRSEE

PRKAB2

186

O43741
TEVRNIDTGPMRFYY

CELSR1

2561

Q9NYQ6
DEARVQYEGFRPGMY

BMS1

871

Q14692
QYEGFRPGMYVRIEI

BMS1

876

Q14692
MAYSPGYFVVDIVAR

CDH23

2921

Q9H251
IYGGNSPAAMTTRYV

AOC3

371

Q16853
GMGLYTIEELNYSPQ

AOX1

1211

Q06278
RGYLGVMPAYSAAED

CRYM

56

Q14894
PVAFLAYRVNGQYIM

OSTC

71

Q9NRP0
APMYYRGAQAAIVVY

RAB5A

86

P20339
APMYYRGAQAAIVVY

RAB5B

86

P61020
LAPMYYRGAQAAIVV

RAB5C

86

P51148
DVVMVYGPMDDQGFY

RIMBP3B

1601

A6NNM3
DVVMVYGPMDDQGFY

RIMBP3C

1601

A6NJZ7
MTVRGTDGAPAYSIY

ODF3B

76

A8MYP8
IPGIRMFQIQYNGTY

LRFN5

441

Q96NI6
VPEQLYQYMVGGHRR

ANAPC1

1321

Q9H1A4
PGEQYTYMLLATEEQ

CP

151

P00450
DYPAIVIYAMIGNDV

AOAH

361

P28039
YVMDDTGLVPGRQYE

PTPRB

431

P23467
FATMIYYAERVGAQP

KCNC2

396

Q96PR1
YGVRQSVPYGMAVVV

JPH2

141

Q9BR39
HGQQMIFPYYGREEE

NOTCH1

1611

P46531
MRAQIPSYSRFYESG

HDX

316

Q7Z353
FVGTPYYMSPEQMNR

NEK2

176

P51955
RNVVDGPYAGVMTAY

MGAT5

66

Q09328
YEAYNMRTGARGVFP

MAPK8IP1

526

Q9UQF2
MRTGARGVFPAYYAI

MAPK8IP1

531

Q9UQF2
VAEDYMIVYLNGATP

ATCAY

226

Q86WG3
ASVPLYQGFLMVGYA

ATP9B

956

O43861
YGVRQSVPYGMATVI

JPH1

141

Q9HDC5
PIIYRGAVYADNMEF

FEM1B

346

Q9UK73
EDIMLVYPAGDQNTY

FSIP2

341

Q5CZC0
PDRFSNTDYAVGYML

CHI3L1

231

P36222
NTDYAVGYMLRLGAP

CHI3L1

236

P36222
YGTMESYQTEAPRHV

COL11A1

311

P12107
DYETADGGYMTLNPR

FCGR2C

286

P31995
GAGIPFLDYRTYAMR

PLXNA1

1316

Q9UIW2
SYSYEGMEINNLPVE

PLXNA4

766

Q9HCM2
YVGTNAYMAPERISG

MAP2K5

316

Q13163
AYMAPERISGEQYGI

MAP2K5

321

Q13163
AMNGEGYLYPSELFT

FGF14

126

Q92915
PAASYGPYTRVQSMA

FOXL2

251

P58012
ERFPYLTGQMARIYG

VEPH1

281

Q14D04
ITIEGVNTPYLYFGM

KDM4A

166

O75164
SARYYTEVITNNGMP

LCT

1351

P09848
AVVVNPEKGYMYFTN

LRP6

1061

O75581
GIMTGPFFRYRTYLD

MBOAT7

161

Q96N66
SGYDEAMNPIRTYQV

EPHB3

66

P54753
AYSAYVPQDGTMLTA

LHX8

311

Q68G74
TPDRLYFVMEYVTGG

PRKCG

426

P05129
PDTNYLFMGDYVDRG

PPP2CB

76

P62714
PDTNYLFMGDYVDRG

PPP2CA

76

P67775
GPVEDMFGYTVQQYE

ITGA1

41

P56199
IDQPTLGMPSREYYF

MMEL1

251

Q495T6
MYYAVSQARVNAVPG

OLIG1

1

Q8TAK6
NEQYGAVRTPYTMGY

RBM4B

191

Q9BQ04
IGYMPQQTGLEDNYV

EPHA7

386

Q15375
MLGYPGFQATTYASR

MSI1

216

O43347
NVVYERVRTYSGPMN

POF1B

46

Q8WVV4
GPQALVQIMRNYSYE

JUP

311

P14923
ERSYFGNMGPQYVTT

ALAS2

571

P22557
VVRIAVHPDYQGMGY

NAT10

626

Q9H0A0
YMRRYNVPATPDGVE

GRIN3A

816

Q8TCU5
TYTMLGTDQEPGIYV

KIF19

111

Q2TAC6
YQIYVQATDRGPVPM

PCDHAC2

331

Q9Y5I4
YGRYDQYKTPMENIG

MCM3

456

P25205
PDETGEYYMLQEQVS

PHF10

81

Q8WUB8
DNSAPYGARYVGSMV

FBP1

236

P09467
VYVYTDMRPGDSVIQ

PCDH15

516

Q96QU1
DSYEPGAYTEGVMRN

CTNNA3

556

Q9UI47
GDQVPYSIMNNYFSI

DGKG

571

P49619
DSEPVVVYGMDYLQQ

EEF1AKMT4-ECE2

476

P0DPD8
PYFAYEGTRDSGMAQ

ATM

1296

Q13315
MGYRIYQEFEVTVPD

CD109

701

Q6YHK3
PREVQMGDFVRYHYN

FKBP10

56

Q96AY3
TMIYYAERIGAQPND

KCNC1

361

P48547
DKTVYMVGSYGPSAQ

ARHGDIG

161

Q99819
QYEMVYRDAQGNPLS

CHD6

551

Q8TD26
YMPYNGSVPFEERIS

ENPP3

286

O14638
SEDAYVGYMTIRFNP

FBXO11

336

Q86XK2
YQYTRPASDVNMLGE

FNIP2

126

Q9P278
TEYRSYNPQKGIGVM

CORO2A

311

Q92828
GEPRHEAYISMEGYQ

HOXD13

216

P35453
AGQSVMYYVFTELPG

A3GALT2

131

U3KPV4
FLPSYQAVEYMRRGE

AGA

266

P20933
MAGYEYVSPEQLAGF

SELENOI

1

Q9C0D9
FYPGMNSILVYVGHE

HGSNAT

601

Q68CP4
YKGEVNSRPTYRMFD

KRCC1

46

Q9NPI7
VEPYRYSGVNMTGFR

GRIK2

266

Q13002
MVERGIAAQPLYAGY

HEXB

536

P07686
EKVMPSRYAAIYNGG

SLC19A2

321

O60779
YPFIRDEGIYAMSGT

SCNN1B

326

P51168
FMGQIVYRGDPYSAH

SLC45A2

341

Q9UMX9
YIGESQGYDIMEPAA

MSH2

856

P43246
IFSPEGRLYQVEYAM

PSMA4

11

P25789
NTYFIVGTAMVYPEE

DDB1

826

Q16531
LQGVSRGMYDGPVYE

CRMP1

491

Q14194
EENYFSDYGPRVMVI

PTCHD3

646

Q3KNS1
NGTPMYLYEVATESV

NR2E1

171

Q9Y466
PFTYQSTRQEGLYAM

OSGIN1

431

Q9UJX0
PVLSYMDLVGFSYQV

PDGFRB

796

P09619
GQYREAGVLMYRDYP

BCKDHA

156

P12694
GQIQGYRVYYTMDPT

PTPRD

446

P23468
ENLMATKYGPVVYAA

RGS13

36

O14921
QMNIVYSGIPEYVGV

MUC17

4221

Q685J3
DTSYYQGVYSRPIMN

FOXA2

441

Q9Y261
QPYTEYMFRLVASNG

USH2A

2501

O75445
SQQLGRVVVGPYMYT

SYT15

376

Q9BQS2
GILYFVDSNEMYGTP

SEL1L3

306

Q68CR1
DEIYEGEYQGIPSMN

SV2C

86

Q496J9
MEVCGEAAGRYPSNY

PTAR1

181

Q7Z6K3
YGMPFSRTEDGKIYQ

SDHA

156

P31040
GLPQRQFYEMYNSVA

PLCE1

116

Q9P212
DVVMVYGPMDDQGFY

RIMBP3

1601

Q9UFD9
ITYGAMNRQEYVPVL

SAMD9

781

Q5K651
YRYMNPAIVAPDGFD

IQGAP2

1106

Q13576
GYPDSVYVMAANIFQ

NSUN7

41

Q8NE18
MEYVPGGELFSYLRN

PRKY

126

O43930
IADQMAYSYRGPQDF

SIPA1L1

1211

O43166
YNGQVMETFVDPTYI

SETMAR

201

Q53H47
RMNFPYFYVAGSVIL

SMIM10L1

46

P0DMW3
QTMDQYSTEPGRYRF

SLC3A1

366

Q07837
YSTEPGRYRFMGTEA

SLC3A1

371

Q07837
DRTVMYYGLPFIQEA

SLC3A1

391

Q07837
MDAVPKIEYYRNTGS

SLC12A1

106

Q13621
IYNYPEQLFGAAGVM

CCT2

296

P78371
EIYYDSNPDFQMVIG

TENM2

2396

Q9NT68
DDMNYGTPISYAVDN

SVEP1

1461

Q4LDE5
GPAARQMLDGYAVTY

SNED1

931

Q8TER0
DSYPDLGIENYGVSM

ABCA8

766

O94911
NEDQGGKYVMYPIAV

ADAM17

426

P78536
EIQYGYRRVNPMYGA

CHSY1

431

Q86X52
EIQYGYRRVNPMHGV

CHSY3

521

Q70JA7
VHGVFYAERYQMPTG

COL10A1

16

Q03692
ENGAFTYYGVPAIMT

CNNM1

691

Q9NRU3
QPYYGFSNQEVIEMV

ROR1

691

Q01973
ASNIMYIVGQYPRFL

XPO1

541

O14980
AKAYRPGVYGNVMVF

TMPRSS2

466

O15393
LAEIQAVFAGPYMEY

SEMA4G

341

Q9NTN9
AVFAGPYMEYQDGSR

SEMA4G

346

Q9NTN9
VPYVGGNMEVNVYGA

VWF

2031

P04275
FVPQMGDEVYYFRQG

PHIP

956

Q8WWQ0
GYEVLPINTQYEGMR

SLC25A46

356

Q96AG3
YAMGVNIYKEGQDVP

MRPL54

71

Q6P161
TEFRYPSYVQHIMGD

UROC1

426

Q96N76
MVALAYSPDGQYIVT

PWP2

376

Q15269
SYYRFGEMQLDFRTP

STT3B

721

Q8TCJ2
YRAMGPYNVAVPSDV

TMEM39A

391

Q9NV64
FLRIYQAMQPVYTSG

TNS1

206

Q9HBL0
MGYQTYPQALTLVFD

NISCH

1421

Q9Y2I1
MNEIVGPLYYTFATD

TBC1D13

231

Q9NVG8
EYGYTITRQDGMFDL

TENM3

891

Q9P273
YSVNDGAQLYMIDPS

PSMA3

141

P25788
RPSRADQFEYVMYGK

POLR2H

81

P52434
MASGAYNPYIEIIEQ

REL

1

Q04864
DYVFRIIYPGMQSEF

SGSM1

416

Q2NKQ1
VTADQYRVYPLMGVS

UPK1A

41

O00322
PVDVAYQRGYFSEEM

PLEC

3621

Q15149
MEYVPGGELFSYLRN

PRKX

126

P51817
YMAEVDRGVYARNPN

ZC3H12B

566

Q5HYM0
PEVGMQRAYGPYSVT

PTPN6

366

P29350
GYQEQMRDSVARIYP

TTC38

156

Q5R3I4
VMQENYGILVSLGYP

ZNF316

186

A6NFI3
YVVVSGNLMYNSFPG

SLC32A1

221

Q9H598
RSVIYEPYLAMFGQV

TRPM8

901

Q7Z2W7
YLAVSLMDPGYVNVQ

ZDHHC12

61

Q96GR4
RVGENDGYMEPYDAQ

SHE

221

Q5VZ18
GQLSGRYEASMYQTP

ZNF777

476

Q9ULD5
AVGTMYRSEGPQVFY

SLC25A19

161

Q9HC21
AGAIPQGRVYEMYVT

UNC5C

556

O95185
GFMDVEVYSYQTQPA

ZP2

376

Q05996
GRVAEDVFTMDYNYP

TUB

471

P50607
YLVNPVGMNRYSVDT

SCML4

236

Q8N228
TMSYYRGQEVLAPGA

TBX21

416

Q9UL17
AYMQPGARENIAYLT

TFIP11

721

Q9UBB9
DDSMGYQYPFTLRVV

USP32

1146

Q8NFA0
LDPSQTDFYGEYVMQ

ZNF641

126

Q96N77
GYGVRQSVPYGMAAV

JPH3

141

Q8WXH2
SPGQLSDYRVENSMY

LEG1

36

Q6P5S2
GNPMEEEKGYRQYVL

LRRC51

136

Q96E66
AQGMPEGDLVYVNYA

NAALAD2

156

Q9Y3Q0
YNPSMGVSVLAPYRE

NECTIN1

81

Q15223