Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctiontransmembrane transporter activity

CACNA1B SLC46A2 ABCC1 SLC25A41 SLC9A8 SLC5A7 SLC17A4 ABCB6 PEX13 SLC24A3 SLC15A3 KCNK7 ABCA10 SLC22A7 SLC6A12 SLC25A32 TOMM70 SLC11A1 CLCN5 CLCN7 SLC12A9 SLC20A2 SLC22A4 GHITM ABCD1 GJC3 VDAC1 SLC22A31

7.87e-1311809628GO:0022857
GeneOntologyMolecularFunctionactive transmembrane transporter activity

SLC46A2 ABCC1 SLC9A8 SLC5A7 SLC17A4 ABCB6 SLC24A3 SLC15A3 ABCA10 SLC22A7 SLC6A12 SLC11A1 CLCN5 CLCN7 SLC12A9 SLC20A2 SLC22A4 GHITM ABCD1

1.11e-124779619GO:0022804
GeneOntologyMolecularFunctiontransporter activity

CACNA1B SLC46A2 ABCC1 SLC25A41 SLC9A8 SLC5A7 SLC17A4 ABCB6 PEX13 SLC24A3 SLC15A3 KCNK7 ABCA10 SLC22A7 SLC6A12 SLC25A32 TOMM70 SLC11A1 CLCN5 CLCN7 SLC12A9 SLC20A2 SLC22A4 GHITM ABCD1 GJC3 VDAC1 SLC22A31

6.56e-1212899628GO:0005215
GeneOntologyMolecularFunctionsecondary active transmembrane transporter activity

SLC46A2 SLC9A8 SLC5A7 SLC17A4 SLC24A3 SLC15A3 SLC22A7 SLC6A12 SLC11A1 CLCN5 CLCN7 SLC12A9 SLC20A2 SLC22A4 GHITM

1.15e-112969615GO:0015291
GeneOntologyMolecularFunctionsymporter activity

SLC46A2 SLC5A7 SLC17A4 SLC24A3 SLC15A3 SLC6A12 SLC12A9 SLC20A2 SLC22A4

4.45e-08150969GO:0015293
GeneOntologyMolecularFunctionactive monoatomic ion transmembrane transporter activity

SLC9A8 SLC5A7 SLC17A4 SLC24A3 SLC15A3 SLC6A12 SLC11A1 SLC12A9 SLC20A2 GHITM

1.88e-063019610GO:0022853
GeneOntologyMolecularFunctioninorganic molecular entity transmembrane transporter activity

CACNA1B ABCC1 SLC9A8 SLC5A7 SLC17A4 SLC24A3 SLC15A3 KCNK7 SLC6A12 SLC11A1 CLCN5 CLCN7 SLC12A9 SLC20A2 GHITM

3.19e-067589615GO:0015318
GeneOntologyMolecularFunctionmonoatomic ion transmembrane transporter activity

CACNA1B SLC9A8 SLC5A7 SLC17A4 SLC24A3 SLC15A3 KCNK7 SLC6A12 SLC11A1 CLCN5 CLCN7 SLC12A9 SLC20A2 GHITM VDAC1

5.52e-067939615GO:0015075
GeneOntologyMolecularFunctionmetal ion transmembrane transporter activity

CACNA1B SLC9A8 SLC5A7 SLC17A4 SLC24A3 KCNK7 SLC6A12 SLC11A1 SLC12A9 SLC20A2 GHITM

1.44e-054659611GO:0046873
GeneOntologyMolecularFunctionnucleotide transmembrane transporter activity

SLC46A2 SLC25A41 SLC25A32 ABCD1

1.84e-0533964GO:0015215
GeneOntologyMolecularFunctioninorganic anion transmembrane transporter activity

ABCC1 SLC17A4 SLC6A12 CLCN5 CLCN7 SLC12A9 SLC20A2

1.88e-05171967GO:0015103
GeneOntologyMolecularFunctionsolute:monoatomic cation symporter activity

SLC5A7 SLC17A4 SLC15A3 SLC6A12 SLC12A9 SLC20A2

2.36e-05119966GO:0015294
GeneOntologyMolecularFunctionorganophosphate ester transmembrane transporter activity

SLC46A2 SLC25A41 SLC25A32 ABCD1

3.63e-0539964GO:0015605
GeneOntologyMolecularFunctioninorganic cation transmembrane transporter activity

CACNA1B SLC9A8 SLC5A7 SLC17A4 SLC24A3 SLC15A3 KCNK7 SLC6A12 SLC11A1 SLC12A9 SLC20A2 GHITM

4.66e-056279612GO:0022890
GeneOntologyMolecularFunctionamide transmembrane transporter activity

ABCC1 SLC15A3 SLC25A32 ABCD1

4.88e-0542964GO:0042887
GeneOntologyMolecularFunctionmetal cation:monoatomic cation antiporter activity

SLC9A8 SLC24A3 SLC11A1 GHITM

5.36e-0543964GO:0140828
GeneOntologyMolecularFunctionantiporter activity

SLC9A8 SLC24A3 SLC11A1 CLCN5 CLCN7 GHITM

5.44e-05138966GO:0015297
GeneOntologyMolecularFunctionvoltage-gated monoatomic anion channel activity

CLCN5 CLCN7 VDAC1

6.97e-0517963GO:0008308
GeneOntologyMolecularFunctionmonoatomic cation transmembrane transporter activity

CACNA1B SLC9A8 SLC5A7 SLC17A4 SLC24A3 SLC15A3 KCNK7 SLC6A12 SLC11A1 SLC12A9 SLC20A2 GHITM

8.06e-056649612GO:0008324
GeneOntologyMolecularFunctionABC-type transporter activity

ABCC1 ABCB6 ABCA10 ABCD1

9.00e-0549964GO:0140359
GeneOntologyMolecularFunctiongalanin receptor activity

GALR2 GAL

1.36e-044962GO:0004966
GeneOntologyMolecularFunctionsodium ion transmembrane transporter activity

SLC9A8 SLC5A7 SLC17A4 SLC24A3 SLC6A12 SLC20A2

1.77e-04171966GO:0015081
GeneOntologyMolecularFunctionpurine ribonucleotide transmembrane transporter activity

SLC46A2 SLC25A41 ABCD1

1.78e-0423963GO:0005346
GeneOntologyMolecularFunctioncarbohydrate derivative transmembrane transporter activity

SLC46A2 SLC25A41 SLC15A3 ABCD1

1.86e-0459964GO:1901505
GeneOntologyMolecularFunctionnucleobase-containing compound transmembrane transporter activity

SLC46A2 SLC25A41 SLC25A32 ABCD1

1.86e-0459964GO:0015932
GeneOntologyMolecularFunctionfibroblast growth factor receptor activity

FGFR3 FGFR4

2.27e-045962GO:0005007
GeneOntologyMolecularFunctionadenine nucleotide transmembrane transporter activity

SLC46A2 SLC25A41 ABCD1

2.58e-0426963GO:0000295
GeneOntologyMolecularFunctiontransmembrane receptor protein tyrosine kinase activity

FLT1 PDGFRA FGFR3 FGFR4

2.71e-0465964GO:0004714
GeneOntologyMolecularFunctionmetal cation:proton antiporter activity

SLC9A8 SLC11A1 GHITM

2.90e-0427963GO:0051139
GeneOntologyMolecularFunctionpurine nucleotide transmembrane transporter activity

SLC46A2 SLC25A41 ABCD1

3.59e-0429963GO:0015216
GeneOntologyMolecularFunctionvascular endothelial growth factor receptor activity

FLT1 PDGFRA

4.73e-047962GO:0005021
GeneOntologyMolecularFunctionmodified amino acid transmembrane transporter activity

ABCC1 SLC25A32 SLC22A4

5.29e-0433963GO:0072349
GeneOntologyMolecularFunctionorganic anion transmembrane transporter activity

SLC46A2 ABCC1 SLC25A41 SLC22A7 SLC6A12 SLC25A32 ABCD1

5.34e-04293967GO:0008514
GeneOntologyMolecularFunctionmacromolecule transmembrane transporter activity

PEX13 SLC15A3 TOMM70

5.78e-0434963GO:0022884
GeneOntologyMolecularFunctionsolute:sodium symporter activity

SLC5A7 SLC17A4 SLC6A12 SLC20A2

6.29e-0481964GO:0015370
GeneOntologyMolecularFunctiontransmembrane receptor protein kinase activity

FLT1 PDGFRA FGFR3 FGFR4

7.54e-0485964GO:0019199
GeneOntologyMolecularFunctionATPase-coupled lipid transmembrane transporter activity

ABCC1 ABCD1

8.06e-049962GO:0034040
GeneOntologyMolecularFunctionmonoatomic anion transmembrane transporter activity

SLC6A12 CLCN5 CLCN7 SLC12A9 VDAC1

8.14e-04151965GO:0008509
GeneOntologyMolecularFunctionvoltage-gated chloride channel activity

CLCN5 CLCN7

1.22e-0311962GO:0005247
GeneOntologyMolecularFunctionsodium:phosphate symporter activity

SLC17A4 SLC20A2

1.46e-0312962GO:0005436
GeneOntologyMolecularFunctioncalcium:monoatomic cation antiporter activity

SLC24A3 GHITM

1.72e-0313962GO:0015368
GeneOntologyMolecularFunctionvoltage-gated monoatomic ion channel activity

CACNA1B KCNK7 CLCN5 CLCN7 VDAC1

1.86e-03182965GO:0005244
GeneOntologyMolecularFunctionATPase-coupled transmembrane transporter activity

ABCC1 ABCB6 ABCA10 ABCD1

1.90e-03109964GO:0042626
GeneOntologyMolecularFunctionvoltage-gated channel activity

CACNA1B KCNK7 CLCN5 CLCN7 VDAC1

1.95e-03184965GO:0022832
GeneOntologyMolecularFunctionneuropeptide receptor activity

GALR2 GAL MRGPRX4

2.12e-0353963GO:0008188
GeneOntologyMolecularFunctionefflux transmembrane transporter activity

ABCC1 ABCB6

2.63e-0316962GO:0015562
GeneOntologyMolecularFunctionoligopeptide transmembrane transporter activity

ABCC1 SLC15A3

2.63e-0316962GO:0035673
GeneOntologyMolecularFunctionchloride transmembrane transporter activity

SLC6A12 CLCN5 CLCN7 SLC12A9

3.12e-03125964GO:0015108
GeneOntologyMolecularFunctioncarboxylic acid transmembrane transporter activity

ABCC1 SLC22A7 SLC6A12 SLC25A32 ABCD1

3.25e-03207965GO:0046943
GeneOntologyMolecularFunctionorganic acid transmembrane transporter activity

ABCC1 SLC22A7 SLC6A12 SLC25A32 ABCD1

3.32e-03208965GO:0005342
GeneOntologyMolecularFunctionlong-chain fatty acid transmembrane transporter activity

ABCC1 ABCD1

3.33e-0318962GO:0005324
GeneOntologyMolecularFunctionsolute:potassium antiporter activity

SLC9A8 SLC24A3

3.71e-0319962GO:0022821
GeneOntologyMolecularFunctionG protein-coupled peptide receptor activity

LTB4R2 GALR2 GAL MRGPRX4

3.89e-03133964GO:0008528
GeneOntologyMolecularFunctionpeptide binding

CACNA1B ERAP1 PEX13 GALR2 TOMM70 MRGPRX4

4.35e-03318966GO:0042277
GeneOntologyMolecularFunctionpeptide receptor activity

LTB4R2 GALR2 GAL MRGPRX4

4.67e-03140964GO:0001653
GeneOntologyMolecularFunctionlipid transmembrane transporter activity

ABCC1 SLC22A7 ABCD1

5.25e-0373963GO:0170055
GeneOntologyMolecularFunctionprotein tyrosine kinase activity

FLT1 PDGFRA FGFR3 FGFR4

5.29e-03145964GO:0004713
GeneOntologyMolecularFunctionfatty acid transmembrane transporter activity

ABCC1 ABCD1

5.42e-0323962GO:0015245
GeneOntologyMolecularFunctionchloride:monoatomic cation symporter activity

SLC6A12 SLC12A9

5.42e-0323962GO:0015377
GeneOntologyMolecularFunctionphosphate transmembrane transporter activity

SLC17A4 SLC20A2

5.89e-0324962GO:0005315
GeneOntologyMolecularFunctiongrowth factor binding

FLT1 PDGFRA FGFR3 FGFR4

6.83e-03156964GO:0019838
GeneOntologyMolecularFunctionmonoatomic anion:monoatomic cation symporter activity

SLC6A12 SLC12A9

6.90e-0326962GO:0015296
GeneOntologyMolecularFunctionfibroblast growth factor binding

FGFR3 FGFR4

7.42e-0327962GO:0017134
GeneOntologyMolecularFunctionprotein transmembrane transporter activity

PEX13 TOMM70

7.97e-0328962GO:0008320
GeneOntologyMolecularFunctionpotassium ion transmembrane transporter activity

SLC9A8 SLC24A3 KCNK7 SLC12A9

8.64e-03167964GO:0015079
GeneOntologyMolecularFunctionmonocarboxylic acid transmembrane transporter activity

ABCC1 SLC6A12 ABCD1

9.36e-0390963GO:0008028
GeneOntologyMolecularFunctionprimary active transmembrane transporter activity

ABCC1 ABCB6 ABCA10 ABCD1

1.07e-02178964GO:0015399
GeneOntologyBiologicalProcessmonoatomic ion transport

CACNA1B ABCC1 SLC9A8 SLC5A7 SLC17A4 ABCB6 SLC24A3 SLC15A3 KCNK7 TF GALR2 SLC22A7 GAL SLC6A12 SLC11A1 CLCN5 CLCN7 SLC12A9 SLC20A2 SLC22A4 GHITM ANTKMT VDAC1 SLC22A31

1.19e-0813749624GO:0006811
GeneOntologyBiologicalProcessmonoatomic ion transmembrane transport

CACNA1B ABCC1 SLC9A8 SLC17A4 ABCB6 SLC24A3 SLC15A3 KCNK7 GALR2 GAL SLC6A12 SLC11A1 CLCN5 CLCN7 SLC12A9 SLC20A2 GHITM ANTKMT VDAC1

7.65e-0711159619GO:0034220
GeneOntologyBiologicalProcessinorganic ion transmembrane transport

CACNA1B SLC9A8 SLC17A4 ABCB6 SLC24A3 SLC15A3 KCNK7 GALR2 GAL SLC6A12 SLC11A1 CLCN5 CLCN7 SLC12A9 SLC20A2 GHITM ANTKMT VDAC1

9.12e-0710179618GO:0098660
GeneOntologyBiologicalProcessmonoatomic cation transport

CACNA1B SLC9A8 SLC5A7 SLC17A4 ABCB6 SLC24A3 SLC15A3 KCNK7 TF GALR2 GAL SLC6A12 SLC11A1 SLC12A9 SLC20A2 SLC22A4 GHITM ANTKMT VDAC1

1.33e-0611579619GO:0006812
GeneOntologyBiologicalProcessmetal ion transport

CACNA1B SLC9A8 SLC5A7 SLC17A4 ABCB6 SLC24A3 KCNK7 TF GALR2 GAL SLC6A12 SLC11A1 SLC12A9 SLC20A2 SLC22A4 GHITM VDAC1

3.30e-0610009617GO:0030001
GeneOntologyBiologicalProcessnucleotide transport

SLC46A2 ABCC1 SLC25A41 SLC25A32 ABCD1

3.53e-0650965GO:0006862
GeneOntologyBiologicalProcessinorganic cation transmembrane transport

CACNA1B SLC9A8 SLC17A4 ABCB6 SLC24A3 SLC15A3 KCNK7 GALR2 GAL SLC6A12 SLC11A1 SLC12A9 SLC20A2 GHITM ANTKMT VDAC1

5.14e-069229616GO:0098662
GeneOntologyBiologicalProcessmonoatomic cation transmembrane transport

CACNA1B SLC9A8 SLC17A4 ABCB6 SLC24A3 SLC15A3 KCNK7 GALR2 GAL SLC6A12 SLC11A1 SLC12A9 SLC20A2 GHITM ANTKMT VDAC1

6.74e-069429616GO:0098655
GeneOntologyBiologicalProcessinorganic anion transport

SLC17A4 SLC11A1 CLCN5 CLCN7 SLC12A9 SLC20A2 FGFR4

2.13e-05180967GO:0015698
GeneOntologyBiologicalProcesspositive regulation of large conductance calcium-activated potassium channel activity

GALR2 GAL

2.14e-052962GO:1902608
GeneOntologyBiologicalProcessmodified amino acid transport

ABCC1 SLC6A12 SLC25A32 SLC22A4

5.19e-0544964GO:0072337
GeneOntologyBiologicalProcesscellular detoxification of cadmium ion

ABCB6 SLC11A1

6.41e-053962GO:0098849
GeneOntologyBiologicalProcesscellular detoxification of metal ion

ABCB6 SLC11A1

6.41e-053962GO:0140961
GeneOntologyBiologicalProcessregulation of large conductance calcium-activated potassium channel activity

GALR2 GAL

6.41e-053962GO:1902606
GeneOntologyBiologicalProcesspotassium ion transmembrane transport

SLC9A8 SLC24A3 KCNK7 GALR2 GAL SLC12A9 GHITM

1.06e-04232967GO:0071805
GeneOntologyBiologicalProcessnegative regulation of lysosome organization

FLCN FNIP1

1.28e-044962GO:1905672
GeneOntologyBiologicalProcessalveolar secondary septum development

FGFR3 FGFR4

1.28e-044962GO:0061144
GeneOntologyBiologicalProcessmitochondrial transmembrane transport

SLC25A41 SLC25A32 TOMM70 GHITM VDAC1

1.37e-04106965GO:1990542
GeneOntologyBiologicalProcessorganic anion transport

SLC46A2 ABCC1 SLC25A41 CYP4A11 SLC17A4 SLC22A7 SLC6A12 SLC25A32 SLC11A1 ABCD1

1.43e-045159610GO:0015711
GeneOntologyBiologicalProcessdetoxification

ABCC1 ABCB6 TXNRD2 SLC11A1 MGST3 SOD3

1.44e-04170966GO:0098754
GeneOntologyBiologicalProcessstress response to cadmium ion

ABCB6 SLC11A1

2.12e-045962GO:1990170
GeneOntologyBiologicalProcessdetoxification of cadmium ion

ABCB6 SLC11A1

2.12e-045962GO:0071585
GeneOntologyBiologicalProcessmonoatomic anion transport

ABCC1 SLC17A4 CLCN5 CLCN7 SLC12A9 VDAC1

2.15e-04183966GO:0006820
GeneOntologyBiologicalProcesspotassium ion transport

SLC9A8 SLC24A3 KCNK7 GALR2 GAL SLC12A9 GHITM

2.82e-04272967GO:0006813
GeneOntologyBiologicalProcessneuropeptide signaling pathway

GALP LTB4R2 GALR2 GAL MRGPRX4

2.86e-04124965GO:0007218
GeneOntologyBiologicalProcesssodium ion transport

SLC9A8 SLC5A7 SLC17A4 SLC24A3 SLC6A12 SLC20A2 SLC22A4

3.01e-04275967GO:0006814
GeneOntologyBiologicalProcesscellular detoxification

ABCB6 TXNRD2 SLC11A1 MGST3 SOD3

3.19e-04127965GO:1990748
GeneOntologyBiologicalProcessnucleotide transmembrane transport

SLC46A2 SLC25A41 SLC25A32

4.00e-0431963GO:1901679
GeneOntologyBiologicalProcessphosphate ion transport

SLC17A4 SLC20A2 FGFR4

4.00e-0431963GO:0006817
GeneOntologyBiologicalProcesscellular response to toxic substance

ABCB6 TXNRD2 SLC11A1 MGST3 SOD3

4.84e-04139965GO:0097237
GeneOntologyBiologicalProcessregulation of pro-B cell differentiation

FLCN FNIP1

5.89e-048962GO:2000973
GeneOntologyBiologicalProcesspositive regulation of nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway

SLC46A2 SLC15A3

5.89e-048962GO:0070426
GeneOntologyBiologicalProcessmonoatomic anion transmembrane transport

ABCC1 CLCN5 CLCN7 SLC12A9 VDAC1

7.47e-04153965GO:0098656
GeneOntologyCellularComponentlysosomal membrane

DAGLB ABCB6 SLC15A3 SLC11A1 CLCN5 CLCN7 AP5B1 AP5M1 FLCN FNIP1 ABCD1

9.82e-064629711GO:0005765
GeneOntologyCellularComponentlytic vacuole membrane

DAGLB ABCB6 SLC15A3 SLC11A1 CLCN5 CLCN7 AP5B1 AP5M1 FLCN FNIP1 ABCD1

9.82e-064629711GO:0098852
GeneOntologyCellularComponentmitochondrial membrane

SLC25A41 ABCB6 MSTO1 SLC25A32 TOMM70 RAB5IF MGST3 SLC22A4 GHITM ANTKMT MRPS5 MIGA1 ABCD1 MIEF2 VDAC1

1.04e-058669715GO:0031966
GeneOntologyCellularComponentmitochondrial envelope

SLC25A41 ABCB6 MSTO1 SLC25A32 TOMM70 RAB5IF MGST3 SLC22A4 GHITM ANTKMT MRPS5 MIGA1 ABCD1 MIEF2 VDAC1

1.92e-059129715GO:0005740
GeneOntologyCellularComponentlysosome

DAGLB ABCB6 SLC15A3 SIAE SLC11A1 FAF2 CLCN5 CLCN7 AP5B1 AP5M1 FLCN FNIP1 FGFR3 ABCD1

2.20e-058119714GO:0005764
GeneOntologyCellularComponentlytic vacuole

DAGLB ABCB6 SLC15A3 SIAE SLC11A1 FAF2 CLCN5 CLCN7 AP5B1 AP5M1 FLCN FNIP1 FGFR3 ABCD1

2.20e-058119714GO:0000323
GeneOntologyCellularComponentvacuolar membrane

DAGLB ABCB6 SLC15A3 SLC11A1 CLCN5 CLCN7 AP5B1 AP5M1 FLCN FNIP1 ABCD1

2.33e-055079711GO:0005774
GeneOntologyCellularComponentvacuole

DAGLB ABCB6 SLC15A3 SIAE SLC11A1 FAF2 CLCN5 CLCN7 AP5B1 AP5M1 FLCN FNIP1 FGFR3 ABCD1

7.96e-059139714GO:0005773
GeneOntologyCellularComponentapical plasma membrane

ABCC1 SLC9A8 CYP4A11 SLC5A7 SLC17A4 TF SLC22A7 SLC20A2 SLC22A4 MTDH

8.83e-054879710GO:0016324
GeneOntologyCellularComponentapical part of cell

ABCC1 SLC9A8 CYP4A11 SLC5A7 SLC17A4 TF SLC22A7 CLCN5 SLC20A2 SLC22A4 MTDH

9.41e-055929711GO:0045177
GeneOntologyCellularComponentAP-5 adaptor complex

AP5B1 AP5M1

1.27e-044972GO:0044599
GeneOntologyCellularComponentmitochondrial outer membrane

ABCB6 MSTO1 TOMM70 MGST3 MIGA1 MIEF2 VDAC1

1.32e-04241977GO:0005741
GeneOntologyCellularComponentorganelle outer membrane

ABCB6 MSTO1 TOMM70 MGST3 MIGA1 MIEF2 VDAC1

3.23e-04279977GO:0031968
GeneOntologyCellularComponentouter membrane

ABCB6 MSTO1 TOMM70 MGST3 MIGA1 MIEF2 VDAC1

3.37e-04281977GO:0019867
GeneOntologyCellularComponentendosome membrane

SLC46A2 SLC9A8 SLC5A7 ABCB6 SLC15A3 TF SLC11A1 CLCN5 AP5M1 OSBPL9

4.83e-046029710GO:0010008
GeneOntologyCellularComponentorganelle envelope

SLC25A41 ABCB6 MSTO1 SLC25A32 TOMM70 RAB5IF MGST3 SLC22A4 GHITM ANTKMT MRPS5 MIGA1 ABCD1 MTDH MIEF2 VDAC1

8.92e-0414359716GO:0031967
GeneOntologyCellularComponentendosome

SLC46A2 FLT1 SLC9A8 SLC5A7 ABCB6 ANKRD50 SLC15A3 TF SLC11A1 CLCN5 AP5B1 AP5M1 OSBPL9 FGFR4

9.63e-0411679714GO:0005768
GeneOntologyCellularComponentlate endosome

SLC9A8 ABCB6 TF SLC11A1 AP5B1 AP5M1 OSBPL9

1.19e-03348977GO:0005770
GeneOntologyCellularComponentlate endosome membrane

SLC9A8 ABCB6 SLC11A1 AP5M1 OSBPL9

1.49e-03179975GO:0031902
GeneOntologyCellularComponent9+2 non-motile cilium

STRC STRCP1

1.87e-0314972GO:0097732
GeneOntologyCellularComponentkinocilium

STRC STRCP1

1.87e-0314972GO:0060091
DomainMFS_dom

SLC46A2 SLC17A4 MFSD6L SLC15A3 SLC22A7 SLC22A4 SLC22A31

4.74e-06134937IPR020846
DomainMFS

SLC46A2 SLC17A4 MFSD6L SLC22A7 SLC22A4 SLC22A31

1.65e-05108936PS50850
DomainGalanin

GALP GAL

2.45e-052932IPR008174
DomainGALANIN

GALP GAL

2.45e-052932PS00861
DomainGalanin

GALP GAL

2.45e-052932PF01296
DomainABC_transporter_CS

ABCC1 ABCB6 ABCA10 ABCD1

5.58e-0542934IPR017871
DomainABC_tran

ABCC1 ABCB6 ABCA10 ABCD1

9.48e-0548934PF00005
DomainABC_TRANSPORTER_2

ABCC1 ABCB6 ABCA10 ABCD1

9.48e-0548934PS50893
DomainABC_TRANSPORTER_1

ABCC1 ABCB6 ABCA10 ABCD1

1.03e-0449934PS00211
DomainABC_transporter-like

ABCC1 ABCB6 ABCA10 ABCD1

1.11e-0450934IPR003439
DomainFGF_rcpt_fam

FGFR3 FGFR4

1.46e-044932IPR016248
DomainABC_TM1F

ABCC1 ABCB6 ABCD1

3.58e-0428933PS50929
DomainABC1_TM_dom

ABCC1 ABCB6 ABCD1

3.58e-0428933IPR011527
DomainMFS_1

SLC46A2 SLC17A4 SLC22A7 SLC22A4

5.91e-0477934PF07690
DomainMFS

SLC46A2 SLC17A4 SLC22A7 SLC22A4

5.91e-0477934IPR011701
DomainTyr_kinase_rcpt_3_CS

FLT1 PDGFRA

6.74e-048932IPR001824
DomainRECEPTOR_TYR_KIN_III

FLT1 PDGFRA

6.74e-048932PS00240
DomainCl-channel_core

CLCN5 CLCN7

8.63e-049932IPR014743
Domain-

CLCN5 CLCN7

8.63e-0499321.10.3080.10
DomainVoltage_CLC

CLCN5 CLCN7

8.63e-049932PF00654
DomainCl-channel_volt-gated

CLCN5 CLCN7

8.63e-049932IPR001807
DomainOrgcat_transp/SVOP

SLC22A7 SLC22A4

8.63e-049932IPR004749
DomainTyrKc

FLT1 PDGFRA FGFR3 FGFR4

9.76e-0488934SM00219
DomainTyr_kinase_cat_dom

FLT1 PDGFRA FGFR3 FGFR4

9.76e-0488934IPR020635
DomainPROTEIN_KINASE_TYR

FLT1 PDGFRA FGFR3 FGFR4

1.40e-0397934PS00109
DomainTyr_kinase_AS

FLT1 PDGFRA FGFR3 FGFR4

1.40e-0397934IPR008266
DomainIg_I-set

FLT1 PDGFRA KIRREL2 FGFR3 FGFR4

2.61e-03190935IPR013098
DomainI-set

FLT1 PDGFRA KIRREL2 FGFR3 FGFR4

2.61e-03190935PF07679
DomainCBS

CLCN5 CLCN7

2.81e-0316932SM00116
DomainPkinase_Tyr

FLT1 PDGFRA FGFR3 FGFR4

3.95e-03129934PF07714
DomainCBS_dom

CLCN5 CLCN7

4.40e-0320932IPR000644
DomainCBS

CLCN5 CLCN7

4.40e-0320932PF00571
DomainCBS

CLCN5 CLCN7

4.40e-0320932PS51371
DomainSer-Thr/Tyr_kinase_cat_dom

FLT1 PDGFRA FGFR3 FGFR4

5.01e-03138934IPR001245
DomainAAA+_ATPase

ABCC1 ABCB6 ABCA10 ABCD1

5.82e-03144934IPR003593
DomainAAA

ABCC1 ABCB6 ABCA10 ABCD1

5.82e-03144934SM00382
DomainABC_membrane

ABCC1 ABCB6

6.30e-0324932PF00664
DomainIGc2

FLT1 PDGFRA KIRREL2 FGFR3 FGFR4

6.41e-03235935SM00408
PathwayREACTOME_TRANSPORT_OF_SMALL_MOLECULES

ABCC1 SLC9A8 SLC5A7 ABCB6 SLC24A3 PSMD2 SLC15A3 TF ABCA10 SLC22A7 SLC6A12 SLC11A1 CLCN5 CLCN7 SLC20A2 SLC22A4 ABCD1 VDAC1

4.35e-097366618M27287
PathwayREACTOME_TRANSPORT_OF_SMALL_MOLECULES

ABCC1 SLC9A8 SLC5A7 ABCB6 SLC24A3 PSMD2 SLC15A3 TF SLC22A7 SLC6A12 SLC11A1 CLCN5 CLCN7 SLC20A2 SLC22A4 ABCD1

6.58e-086816616MM14985
PathwayREACTOME_SLC_MEDIATED_TRANSMEMBRANE_TRANSPORT

SLC9A8 SLC5A7 SLC24A3 SLC15A3 SLC22A7 SLC6A12 SLC11A1 SLC20A2 SLC22A4

1.54e-06238669MM15076
PathwayREACTOME_SLC_MEDIATED_TRANSMEMBRANE_TRANSPORT

SLC9A8 SLC5A7 SLC24A3 SLC15A3 SLC22A7 SLC6A12 SLC11A1 SLC20A2 SLC22A4

2.23e-06249669M5988
PathwayKEGG_MEDICUS_REFERENCE_REGULATION_OF_GF_RTK_RAS_ERK_SIGNALING_UBIQUITINATION_OF_RTK_BY_CBL

FLT1 PDGFRA FGFR3 FGFR4

5.15e-0625664M47934
PathwayREACTOME_TRANSPORT_OF_BILE_SALTS_AND_ORGANIC_ACIDS_METAL_IONS_AND_AMINE_COMPOUNDS

SLC5A7 SLC22A7 SLC6A12 SLC11A1 SLC22A4

2.76e-0576665MM15072
PathwayREACTOME_TRANSPORT_OF_BILE_SALTS_AND_ORGANIC_ACIDS_METAL_IONS_AND_AMINE_COMPOUNDS

SLC5A7 SLC22A7 SLC6A12 SLC11A1 SLC22A4

4.48e-0584665M27334
PathwayKEGG_ABC_TRANSPORTERS

ABCC1 ABCB6 ABCA10 ABCD1

5.17e-0544664M11911
PathwayREACTOME_ABC_FAMILY_PROTEINS_MEDIATED_TRANSPORT

ABCC1 ABCB6 PSMD2 ABCA10 ABCD1

1.19e-04103665M758
PathwayKEGG_MEDICUS_REFERENCE_RTK_PLCG_ITPR_SIGNALING_PATHWAY

FLT1 PDGFRA FGFR3 FGFR4

1.25e-0455664M47952
PathwayREACTOME_TRANSPORT_OF_INORGANIC_CATIONS_ANIONS_AND_AMINO_ACIDS_OLIGOPEPTIDES

SLC9A8 SLC24A3 SLC15A3 SLC6A12 SLC20A2

1.48e-04108665M823
PathwayREACTOME_TRANSPORT_OF_INORGANIC_CATIONS_ANIONS_AND_AMINO_ACIDS_OLIGOPEPTIDES

SLC9A8 SLC24A3 SLC15A3 SLC6A12 SLC20A2

1.55e-04109665MM15074
PathwayKEGG_MEDICUS_REFERENCE_GF_RTK_PI3K_SIGNALING_PATHWAY

FLT1 PDGFRA FGFR3 FGFR4

6.10e-0483664M47961
PathwayKEGG_MEDICUS_VARIANT_MUTATION_INACTIVATED_OPTN_TO_PINK_PARKIN_MEDIATED_AUTOPHAGOSOME_FORMATION

TOMM70 FAF2

7.61e-049662M47743
PathwayKEGG_MEDICUS_REFERENCE_GF_RTK_RAS_PI3K_SIGNALING_PATHWAY

FLT1 PDGFRA FGFR3 FGFR4

7.94e-0489664M47963
PathwayWP_SMITHMAGENIS_AND_POTOCKILUPSKI_SYNDROME_COPY_NUMBER_VARIATION

IQCA1 FLCN FNIP1 MIGA1 MIEF2

8.80e-04159665M48090
PathwayKEGG_MEDICUS_REFERENCE_GF_RTK_RAS_ERK_SIGNALING_PATHWAY

FLT1 PDGFRA FGFR3 FGFR4

8.99e-0492664M47927
Pubmed

FGF receptors control alveolar elastogenesis.

PDGFRA FGFR3 FGFR4

2.16e-07598329122839
Pubmed

Quantitative high-confidence human mitochondrial proteome and its dynamics in cellular context.

ABCB6 TXNRD2 MSTO1 SLC25A32 TOMM70 MGST3 FLAD1 SLC22A4 GHITM C15orf61 ANTKMT MRPS5 MIGA1 MIEF2 VDAC1

6.79e-071136981534800366
Pubmed

Association study between single-nucleotide polymorphisms in 199 drug-related genes and commonly measured quantitative traits of 752 healthy Japanese subjects.

ABCC1 CYP4A11 ALDH8A1 ABCB6 SLC22A7 MGST3 ABCD1

1.31e-0619398719343046
Pubmed

C5orf51 is a component of the MON1-CCZ1 complex and controls RAB7A localization and stability during mitophagy.

PEX13 ANKRD50 FAF2 CLCN7 MEGF8 OSBPL9 FLCN FNIP1 MIGA1 MTDH

1.68e-06504981034432599
Pubmed

Galanin/GALP receptors and CNS homeostatic processes.

GALP GAL

7.86e-06298216787232
Pubmed

Galanin decreases proliferation of PC12 cells and induces apoptosis via its subtype 2 receptor (GalR2).

GALR2 GAL

7.86e-06298218272487
Pubmed

Distinct features of neurotransmitter systems in the human brain with focus on the galanin system in locus coeruleus and dorsal raphe.

GALR2 GAL

7.86e-06298223341594
Pubmed

The neuropeptide galanin is a novel inhibitor of human hair growth.

GALR2 GAL

7.86e-06298222329353
Pubmed

Mutations in a new gene encoding a protein of the hair bundle cause non-syndromic deafness at the DFNB16 locus.

STRC STRCP1

7.86e-06298211687802
Pubmed

Circulating galanin and galanin like peptide concentrations are correlated with increased triglyceride concentration in obese patients.

GALP GAL

7.86e-06298227474259
Pubmed

Structure of the human galanin receptor 2 bound to galanin and Gq reveals the basis of ligand specificity and how binding affects the G-protein interface.

GALR2 GAL

7.86e-06298235913979
Pubmed

FGFR-3 and FGFR-4 function cooperatively to direct alveogenesis in the murine lung.

FGFR3 FGFR4

7.86e-0629829716527
Pubmed

Fibroblast growth factor receptors control epithelial-mesenchymal interactions necessary for alveolar elastogenesis.

FGFR3 FGFR4

7.86e-06298220093646
Pubmed

Association of FGFR3 and FGFR4 gene polymorphisms with breast cancer in Chinese women of Heilongjiang province.

FGFR3 FGFR4

7.86e-06298226431494
Pubmed

Altered expressions of fibroblast growth factor receptors and alveolarization in neonatal mice exposed to 85% oxygen.

FGFR3 FGFR4

7.86e-06298217957151
Pubmed

Dual-vector gene therapy restores cochlear amplification and auditory sensitivity in a mouse model of DFNB16 hearing loss.

STRC STRCP1

7.86e-06298234910522
Pubmed

Solute carrier 11a1 (Slc11a1; formerly Nramp1) regulates metabolism and release of iron acquired by phagocytic, but not transferrin-receptor-mediated, iron uptake.

TF SLC11A1

7.86e-06298211903051
Pubmed

A role for galanin in human and experimental inflammatory demyelination.

GALR2 GAL

7.86e-06298219717462
Pubmed

Galanin is a modulator of eccrine sweat gland secretion.

GALR2 GAL

7.86e-06298223278944
Pubmed

GATOR1-dependent recruitment of FLCN-FNIP to lysosomes coordinates Rag GTPase heterodimer nucleotide status in response to amino acids.

FLCN FNIP1

7.86e-06298229848618
Pubmed

Elevated fibroblast growth factor 23 exerts its effects on placenta and regulates vitamin D metabolism in pregnancy of Hyp mice.

SLC20A2 FGFR3 FGFR4

1.18e-051698324470103
Pubmed

The cell surface receptor FGFRL1 forms constitutive dimers that promote cell adhesion.

FGFR3 FGFR4

2.35e-05398218061161
Pubmed

An alternative mechanism of clathrin-coated pit closure revealed by ion conductance microscopy.

CLCN5 CLCN7

2.35e-05398222564416
Pubmed

Cochlear outer hair cell horizontal top connectors mediate mature stereocilia bundle mechanics.

STRC STRCP1

2.35e-05398230801007
Pubmed

Galanin expression is down-regulated in patients with gastric cancer.

GALR2 GAL

2.35e-05398230616468
Pubmed

Compound deletion of Fgfr3 and Fgfr4 partially rescues the Hyp mouse phenotype.

FGFR3 FGFR4

2.35e-05398221139072
Pubmed

Dihydromyricetin prevents obesity-induced slow-twitch-fiber reduction partially via FLCN/FNIP1/AMPK pathway.

FLCN FNIP1

2.35e-05398228363698
Pubmed

Lysosomal degradation of endocytosed proteins depends on the chloride transport protein ClC-7.

CLCN5 CLCN7

2.35e-05398219661288
Pubmed

The folliculin-FNIP1 pathway deleted in human Birt-Hogg-Dubé syndrome is required for murine B-cell development.

FLCN FNIP1

2.35e-05398222709692
Pubmed

Crystal structure of folliculin reveals a hidDENN function in genetically inherited renal cancer.

FLCN FNIP1

2.35e-05398222977732
Pubmed

Epigenetic inactivation of galanin and GALR1/2 is associated with early recurrence in head and neck cancer.

GALR2 GAL

2.35e-05398226572146
Pubmed

Regulation of serum 1,25(OH)2 vitamin D3 levels by fibroblast growth factor 23 is mediated by FGF receptors 3 and 4.

FGFR3 FGFR4

2.35e-05398221561999
Pubmed

Molecular characterization, pharmacological properties and chromosomal localization of the human GALR2 galanin receptor.

GALR2 GAL

2.35e-0539829685625
Pubmed

The role of galanin system in modulating depression, anxiety, and addiction-like behaviors after chronic restraint stress.

GALR2 GAL

2.35e-05398223639882
Pubmed

Loss of FLCN-FNIP1/2 induces a non-canonical interferon response in human renal tubular epithelial cells.

FLCN FNIP1

2.35e-05398233459596
Pubmed

Site-specific methylation patterns of the GAL and GALR1/2 genes in head and neck cancer: Potential utility as biomarkers for prognosis.

GALR2 GAL

2.35e-05398227685843
Pubmed

Peptides containing the RERMS sequence of amyloid beta/A4 protein precursor bind cell surface and promote neurite extension.

FGFR3 FGFR4

2.35e-0539828083748
Pubmed

MTDH in macrophages promotes the vasculogenic mimicry via VEGFA-165/Flt-1 signaling pathway in head and neck squamous cell carcinoma.

FLT1 MTDH

2.35e-05398234162144
Pubmed

[Expression of galanin and galanin receptors in neurogenesis regions of adult mouse brain and effect of galanin on the neural stem cell's differentiation].

GALR2 GAL

2.35e-05398219127771
Pubmed

Galanin pathogenic mutations in temporal lobe epilepsy.

GALR2 GAL

2.35e-05398225691535
Pubmed

Identification of novel protein kinases expressed in the myocardium of the developing mouse heart.

FLT1 PDGFRA FGFR4

2.39e-05209837893599
Pubmed

Defining the membrane proteome of NK cells.

ABCC1 PDGFRA ERAP1 PEX13 PSMD2 LTB4R2 TOMM70 DNAJC10 CLCN5 CLCN7 MGST3 ABCD1 PIGO

2.47e-051168981319946888
Pubmed

Integral and associated lysosomal membrane proteins.

DAGLB SLC15A3 CLCN5 CLCN7 AP5B1

2.99e-0512698517897319
Pubmed

ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.

ABCC1 ERAP1 PSMD2 GAL SIAE DNAJC10 MEGF8 MGST3 OSBPL9 FLCN FGFR4 MTDH PIGO

3.29e-051201981335696571
Pubmed

A genome-wide association study identifies a functional ERAP2 haplotype associated with birdshot chorioretinopathy.

ERAP1 TECPR2

4.70e-05498224957906
Pubmed

Stereocilin-deficient mice reveal the origin of cochlear waveform distortions.

STRC STRCP1

4.70e-05498218849963
Pubmed

Fgfr3 expression by astrocytes and their precursors: evidence that astrocytes and oligodendrocytes originate in distinct neuroepithelial domains.

PDGFRA FGFR3

4.70e-05498212441294
Pubmed

Responsiveness of developing dental tissues to fibroblast growth factors: expression of splicing alternatives of FGFR1, -2, -3, and of FGFR4; and stimulation of cell proliferation by FGF-2, -4, -8, and -9.

FGFR3 FGFR4

4.70e-0549829664689
Pubmed

PCR-based identification of new receptors: molecular cloning of a receptor for fibroblast growth factors.

FLT1 PDGFRA

4.70e-0549821711190
Pubmed

The second galanin receptor GalR2 plays a key role in neurite outgrowth from adult sensory neurons.

GALR2 GAL

4.70e-05498212533601
Pubmed

Coordinated Targeting of Galanin Receptors on Cholangiocytes and Hepatic Stellate Cells Ameliorates Liver Fibrosis in Multidrug Resistance Protein 2 Knockout Mice.

GALR2 GAL

4.70e-05498231953035
Pubmed

Interaction of folliculin (Birt-Hogg-Dubé gene product) with a novel Fnip1-like (FnipL/Fnip2) protein.

FLCN FNIP1

4.70e-05498218663353
Pubmed

Chloride and the endosomal-lysosomal pathway: emerging roles of CLC chloride transporters.

CLCN5 CLCN7

4.70e-05498217110406
Pubmed

Induction of lysosomal and mitochondrial biogenesis by AMPK phosphorylation of FNIP1.

FLCN FNIP1

4.70e-05498237079666
Pubmed

The fifth adaptor protein complex.

AP5B1 AP5M1

4.70e-05498222022230
Pubmed

Differential expression of the fibroblast growth factor receptor (FGFR) multigene family in normal human adult tissues.

FGFR3 FGFR4

4.70e-0549829212826
Pubmed

Brain galanin system genes interact with life stresses in depression-related phenotypes.

GALR2 GAL

4.70e-05498224706871
Pubmed

Folliculin variants linked to Birt-Hogg-Dubé syndrome are targeted for proteasomal degradation.

FLCN FNIP1

4.70e-05498233137092
Pubmed

Expression of fibroblast growth factor receptor family members is associated with prognosis in early stage cervical cancer patients.

FGFR3 FGFR4

4.70e-05498227154171
Pubmed

Amplification of FRS2 and activation of FGFR/FRS2 signaling pathway in high-grade liposarcoma.

FGFR3 FGFR4

4.70e-05498223393200
Pubmed

Immunolocalization of fibroblast growth factor receptors in normal and wounded human skin.

FGFR3 FGFR4

4.70e-05498212373339
Pubmed

FGFR1-4 RNA-Based Gene Alteration and Expression Analysis in Squamous Non-Small Cell Lung Cancer.

FGFR3 FGFR4

4.70e-05498236142417
Pubmed

K-ras mutation status correlates with the expression of VEGFR1, VEGFR2, and PDGFRalpha in colorectal cancer.

FLT1 PDGFRA

4.70e-05498219936766
Pubmed

Alcoholism is associated with GALR3 but not two other galanin receptor genes.

GALR2 GAL

4.70e-05498217083333
Pubmed

Immunohistochemical detection of fibroblast growth factor receptors in normal endocrine cells and related tumors of the digestive system.

FGFR3 FGFR4

4.70e-05498211759058
Pubmed

Folliculin-interacting proteins Fnip1 and Fnip2 play critical roles in kidney tumor suppression in cooperation with Flcn.

FLCN FNIP1

4.70e-05498225775561
Pubmed

SOD3 regulates FLT1 to affect bone metabolism by promoting osteogenesis and inhibiting adipogenesis through PI3K/AKT and MAPK pathways.

FLT1 SOD3

4.70e-05498238141889
Pubmed

The FGF system has a key role in regulating vascular integrity.

FGFR3 FGFR4

4.70e-05498218776942
Pubmed

Activation of galanin receptor 2 stimulates large conductance Ca(2+)-dependent K(+) (BK) channels through the IP3 pathway in human embryonic kidney (HEK293) cells.

GALR2 GAL

4.70e-05498224602615
Pubmed

RNAi-based conditional gene knockdown in mice using a U6 promoter driven vector.

FGFR3 FGFR4

4.70e-05498217304337
Pubmed

Expression of basic fibroblast growth factor and its receptors in human ovarian follicles from adults and fetuses.

FGFR3 FGFR4

4.70e-05498216210019
Pubmed

Differential expression of fibroblast growth factor receptors in the developing murine choroid plexus.

FGFR3 FGFR4

4.70e-05498212644244
Pubmed

Peroxisome Metabolism Contributes to PIEZO2-Mediated Mechanical Allodynia.

GALR2 GAL ABCD1

4.77e-052598335681537
Pubmed

Distinct association of genetic variations of vascular endothelial growth factor, transforming growth factor-beta, and fibroblast growth factor receptors with atopy and airway hyperresponsiveness.

FLT1 FGFR4

7.82e-05598218315732
Pubmed

Efficient regulation of branching morphogenesis via fibroblast growth factor receptor 2c in early-stage embryonic mouse salivary glands.

FGFR3 FGFR4

7.82e-05598227206683
Pubmed

Conditional knockdown of Fgfr2 in mice using Cre-LoxP induced RNA interference.

FGFR3 FGFR4

7.82e-05598215987787
Pubmed

Transporter gene expression in lactating and nonlactating human mammary epithelial cells using real-time reverse transcription-polymerase chain reaction.

ABCC1 SLC22A4

7.82e-05598212388627
Pubmed

The expression profiles of fibroblast growth factor 9 and its receptors in developing mice testes.

FGFR3 FGFR4

7.82e-05598227078042
Pubmed

Different intracellular trafficking of FGF1 endocytosed by the four homologous FGF receptors.

FGFR3 FGFR4

7.82e-05598216091423
Pubmed

FGF-dependent regulation of VEGF receptor 2 expression in mice.

FGFR3 FGFR4

7.82e-05598221633168
Pubmed

Derlin-1 and UBXD8 are engaged in dislocation and degradation of lipidated ApoB-100 at lipid droplets.

PSMD2 FAF2

7.82e-05598222238364
Pubmed

Expression of fibroblast growth factor receptors in peri-implantation mouse embryos.

FGFR3 FGFR4

7.82e-0559829771645
Pubmed

Persistent fibroblast growth factor 23 signalling in the parathyroid glands for secondary hyperparathyroidism in mice with chronic kidney disease.

FGFR3 FGFR4

7.82e-05598228094278
Pubmed

Voltage-Gated Ion Channels Are Transcriptional Targets of Sox10 during Oligodendrocyte Development.

CACNA1B PDGFRA

7.82e-05598238995010
Pubmed

Coevolution of the spexin/galanin/kisspeptin family: Spexin activates galanin receptor type II and III.

GALR2 GAL

7.82e-05598224517231
Pubmed

An essential role for ClC-4 in transferrin receptor function revealed in studies of fibroblasts derived from Clcn4-null mice.

TF CLCN5

7.82e-05598219339555
Pubmed

Functional TFEB activation characterizes multiple models of renal cystic disease and loss of polycystin-1.

FLCN FNIP1

7.82e-05598236794754
Pubmed

Inactivation of the FLCN tumor suppressor gene induces TFE3 transcriptional activity by increasing its nuclear localization.

FLCN FNIP1

7.82e-05598221209915
Pubmed

Overlapping expression and redundant activation of mesenchymal fibroblast growth factor (FGF) receptors by alternatively spliced FGF-8 ligands.

FGFR3 FGFR4

7.82e-0559829013630
Pubmed

An unusually powerful mode of low-frequency sound interference due to defective hair bundles of the auditory outer hair cells.

STRC STRCP1

7.82e-05598224920589
Pubmed

The mouse Fgfrl1 gene coding for a novel FGF receptor-like protein.

FGFR3 FGFR4

7.82e-05598211566361
Pubmed

The protein tyrosine kinase family of the human genome.

FLT1 PDGFRA FGFR3 FGFR4

9.18e-058398411114734
Pubmed

Identification and characterization of a novel folliculin-interacting protein FNIP2.

FLCN FNIP1

1.17e-04698218403135
Pubmed

Fgfr1 and Fgfr2 have distinct differentiation- and proliferation-related roles in the developing mouse skull vault.

FGFR3 FGFR4

1.17e-04698210572038
Pubmed

Galanin promotes neuronal differentiation from neural progenitor cells in vitro and contributes to the generation of new olfactory neurons in the adult mouse brain.

GALR2 GAL

1.17e-04698224726665
Pubmed

FGF2 concentration regulates the generation of neurons and glia from multipotent cortical stem cells.

FGFR3 FGFR4

1.17e-0469829010207
Pubmed

Trans-activation of EphA4 and FGF receptors mediated by direct interactions between their cytoplasmic domains.

FGFR3 FGFR4

1.17e-04698216365308
Pubmed

FGFR3 and FGFR4 do not mediate renal effects of FGF23.

FGFR3 FGFR4

1.17e-04698218753255
Pubmed

Regulation of fibroblast growth factor-23 signaling by klotho.

FGFR3 FGFR4

1.17e-04698216436388
Pubmed

Neuron-derived FGF9 is essential for scaffold formation of Bergmann radial fibers and migration of granule neurons in the cerebellum.

FGFR3 FGFR4

1.17e-04698219232523
CytobandEnsembl 112 genes in cytogenetic band chr5q31

PCDHA4 PCDHA3 SLC22A4 FNIP1 SMIM33 VDAC1

4.28e-05298976chr5q31
Cytoband11q24

SIAE TP53AIP1

5.20e-041697211q24
GeneFamilySolute carriers

SLC46A2 SLC25A41 SLC9A8 SLC5A7 SLC17A4 SLC24A3 SLC15A3 SLC22A7 SLC6A12 SLC25A32 SLC11A1 SLC12A9 SLC20A2 SLC22A4 SLC22A31

1.46e-113956815752
GeneFamilyReceptor Tyrosine Kinases|CD molecules

FLT1 PDGFRA FGFR3 FGFR4

1.51e-0540684321
GeneFamilyBlood group antigens|CD molecules|I-set domain containing|Immunoglobulin like domain containing

FLT1 PDGFRA KIRREL2 FGFR3 FGFR4

3.49e-04161685593
GeneFamilyChloride voltage-gated channels

CLCN5 CLCN7

6.15e-0410682302
GeneFamilyGlycosyl transferases group 1 domain containing|Phosphatidylinositol glycan anchor biosynthesis

PIGZ PIGO

2.79e-0321682680
GeneFamilyGuanylate cyclase receptors|DENN/MADD domain containing

FLCN FNIP1

3.95e-0325682504
ToppCelldroplet-Kidney-nan-18m-Epithelial-Epcam____brush_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC9A8 ALDH8A1 GALR2 SLC22A7 IQCA1 FGFR3

1.79e-06167976ed7e785dcd25777f64e0c2596ada4f5a5ea17121
ToppCell5'-GW_trimst-2-LargeIntestine-Neuronal-Glial_immature-ENCC/glia_Progenitor|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ANKRD50 SLC15A3 LGI4 TF GAL GJC3

1.85e-06168976948d9e9972bd2a4b503d55fa69b70dd568a35a67
ToppCellcontrol-Myeloid-Monocyte-derived_DC|Myeloid / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

PSMD2 FAF2 RAB5IF MGST3 VDAC1

3.92e-06108975e74e73d89d78c8d59dfdd2bd30db54b366a49d23
ToppCell5'-GW_trimst-2-LargeIntestine-Neuronal-Glial_immature-Glia_3_(BCAN+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ANKRD50 SLC15A3 LGI4 TF RGR GJC3

4.91e-06199976a76aa30fb264bdcbc0cb09113f814fc5a89e7319
ToppCell10x5'v1-week_12-13-Hematopoietic-HSC/MPP_and_pro-HSC/MPP|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

AMER1 MFSD6L IQCA1 GJC3 MPPED1

2.72e-0516197546b5d80d2d521fb69752aba4c10383e715a32002
ToppCelldroplet-Kidney-KIDNEY-1m-Epithelial-brush_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC9A8 ALDH8A1 SLC22A7 MPPED1 SOD3

2.81e-051629756972d45f4bd4b6522bf93295f7e9dca7c6cba1f3
ToppCelldroplet-Kidney-nan-18m-Epithelial-brush_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC9A8 ALDH8A1 GALR2 SLC22A7 IQCA1

3.44e-05169975f00741203efa0b948db7223ee8c19bdd0918258a
ToppCelldroplet-Kidney-nan-3m-Epithelial-brush_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC9A8 ALDH8A1 SLC24A3 SLC22A7 MPPED1

3.53e-05170975dd48fd3c5c67eb71183981f42975a538f12077c3
ToppCellMonocytes-IFN-activated_Monocytes|World / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues

FLT1 ATF5 SLC15A3 SLC11A1 STRC

3.63e-05171975df1b631618839bee4a18a2ba9c730321e5015f36
ToppCellTCGA-Colorectal-Recurrent_Tumor|TCGA-Colorectal / Sample_Type by Project: Shred V9

CYP4A11 ALDH8A1 TF SLC22A7 MPPED1

4.06e-051759757f74961436f88c0e380819095e6104489914d765
ToppCellTCGA-Colorectal-Recurrent_Tumor-Colorectal_Adenocarcinoma|TCGA-Colorectal / Sample_Type by Project: Shred V9

CYP4A11 ALDH8A1 TF SLC22A7 MPPED1

4.06e-05175975bee8f31f036dfcf9fc6ed29156554771a9ee3c60
ToppCellfacs-Kidney-nan-18m-Epithelial-epithelial_cell_of_proximal_tubule|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC9A8 ALDH8A1 GALR2 SLC22A7 SOD3

4.06e-05175975076ad81d6cbeea5512393d192af3ab5aa1f82975
ToppCellfacs-Kidney-nan-18m-Epithelial-epithelial_cell_of_proximal_tubule|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC9A8 ALDH8A1 GALR2 SLC22A7 SOD3

4.06e-05175975445ccb9744a3a9ff37164c532afbe769d306b6c8
ToppCellfacs-Marrow-KLS-18m-Lymphocytic-late_pro-B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCB6 SYDE1 SLC12A9 AP5M1 MMP11

4.17e-051769753766e0533b103ec92ac75eba3df02e287efc53fa
ToppCellfacs-Marrow-KLS-18m-Lymphocytic-late_pro_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCB6 SYDE1 SLC12A9 AP5M1 MMP11

4.17e-05176975aa1bada2175d8370fc71939a607407155259d195
ToppCellNS-moderate-d_16-33-Lymphoid-NK|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

PDGFRA SLC24A3 SYDE1 GAL SOD3

4.89e-05182975fb503f8ecd013f1f2161a5841572b57cfcddb6fa
ToppCellfacs-Skin-Skin_Anagen-18m-Mesenchymal-fibroblast|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PDGFRA LGI4 C15orf61 FGFR4 SOD3

5.15e-05184975fea4fe648e9749177d0783443dc26a7df5807883
ToppCellTCGA-Lung-Primary_Tumor-Lung_Carcinoma-Lung_Squamous_Cell_Carcinoma-3|TCGA-Lung / Sample_Type by Project: Shred V9

CACNA1B ABCC1 AMER1 PSMD2 MPPED1

5.15e-05184975ea4ccebe2d54279fcc517e4f0bfa652b91a808bb
ToppCellPCW_13-14-Neuronal|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

SLC5A7 SLC15A3 LGI4 TTLL7 GAL

5.15e-0518497565cf3460125e3dbc34978957bc138a449f71f7df
ToppCellfacs-Skin-Skin_Anagen-18m-Mesenchymal-nan|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PDGFRA LGI4 C15orf61 FGFR4 SOD3

5.15e-0518497596a8a0a190bc293655fe7d80cbed8119c0da25f2
ToppCellfacs-Skin-Skin_Anagen-18m-Mesenchymal|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PDGFRA LGI4 C15orf61 FGFR4 SOD3

5.15e-05184975780eb72da43527f0c72effac3423ec7384f05f20
ToppCelldroplet-Liver-HEPATOCYTES-1m-Mesenchymal-hepatic_stellate_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PDGFRA SYDE1 MMP11 ADAMTSL4 SOD3

5.56e-05187975b6ecf55014f246461bf1ca12f24cb4d046661fa4
ToppCelldroplet-Liver-HEPATOCYTES-1m-Mesenchymal-hepatic_stellate_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PDGFRA SYDE1 MMP11 ADAMTSL4 SOD3

5.56e-051879759fb15f24b9b364b0c4704ec98aec236eaec5411c
ToppCelldroplet-Liver-HEPATOCYTES-1m-Mesenchymal|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PDGFRA SYDE1 MMP11 ADAMTSL4 SOD3

5.56e-05187975e6afbaed352310a1cb49571a2aae18be1f533c9a
ToppCellPCW_05-06-Mesenchymal-Mesenchymal_fibroblastic-mes_adventitial_fibro_(10)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

SLC5A7 SLC24A3 IQCA1 MMP11 SOD3

6.15e-05191975156b467187331ac6ca390d6ca861d9670bb7b956
ToppCell3'-Broncho-tracheal-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophages-Alveolar_macrophages_L.1.0.0.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CELA2B SLC15A3 SLC11A1 MGST3 ADAMTSL4

6.61e-05194975412c2b8eb522da6c84f8b00d32d6f0bee555251f
ToppCell15-Airway-Epithelial-Epithelial|Airway / Age, Tissue, Lineage and Cell class

CACNA1B SLC5A7 SLC15A3 LGI4 GAL

6.78e-0519597556356a9aeb67b50a74425be2cd9c50d31416c1b3
ToppCell3'-GW_trimst-2-SmallIntestine-Neuronal-Glial_immature-Glia_3_(BCAN+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SLC15A3 LGI4 TF RGR GJC3

7.11e-05197975bb35a2b7320fda92e9cd42f536b7bd54e3a73a32
ToppCell5'-GW_trimst-2-SmallIntestine-Neuronal-Glial_immature|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ANKRD50 SLC15A3 LGI4 TF GJC3

7.28e-0519897550dfe6efca76ea9683a19b6bff59cb5030d346f1
ToppCell5'-GW_trimst-2-SmallIntestine-Neuronal|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SLC5A7 SLC15A3 LGI4 TF GAL

7.28e-051989756e314dc820db9c53fe7fc7c96bed4d7d9a325160
ToppCell5'-GW_trimst-2-LargeIntestine-Neuronal|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SLC15A3 LGI4 TF GAL GJC3

7.46e-051999755f350d9c7da9ac111bf22623dd4fed7f7983c9fc
ToppCell5'-GW_trimst-2-LargeIntestine-Neuronal-Glial_immature|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ANKRD50 SLC15A3 LGI4 TF GJC3

7.64e-05200975363a8cebf2ace820661bcb87c7941f6671f8e5f3
ToppCellBronchus_Control_(B.)-Stromal-TX-Fibroblasts-1|Bronchus_Control_(B.) / Sample group, Lineage and Cell type

PDGFRA ABCA10 FGFR4 SOD3 SLC22A31

7.64e-0520097516a3685c41194a0a4a772e4eee372160263480e0
ToppCellSubstantia_nigra-Macroglia-ASTROCYTE|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

LGI4 KCNK7 SLC22A4 FGFR3

2.10e-04134974a632d78890fcc20db81d2cf6b299470706d2e182
ToppCellSubstantia_nigra-Macroglia-ASTROCYTE-Gja1|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

LGI4 KCNK7 SLC22A4 FGFR3

2.10e-041349748be2db71d9d29f9a57a64efdc89cf8c3e32b363b
ToppCellControl-Myeloid-Dendritic_cells|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

TTC24 CELA2B CLCN5 MMP11

2.70e-04143974bb8d4c335682d1a6798bed0de8bb0603054a4944
ToppCellLPS-antiTNF-Myeloid-Monocytes,_Macrophages-Erythroid|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CACNA1B FLT1 ATF5 IQCA1

2.77e-041449741b9e95e4f6e40042d3cf2f94c067f3a6b19428ea
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Lmo1_Myl1|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

ATF5 SLC5A7 SLC24A3 FGFR3

2.77e-041449740322fef818a963be00535d5f141f028d43de5c6a
ToppCellControl-Myeloid-Dendritic_cells-pDC|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

TTC24 CELA2B CLCN5 MMP11

2.84e-04145974bab85a72142b6257f7d424e5301f65b6dcdf745d
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-Degenerative_Endothelial_Cell-Degenerative_Peritubular_Capilary_Endothelial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

FLT1 SLC11A1 GHITM FGFR3

2.84e-041459742eebf2294c53f081d3b0169071388e477a195218
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PDGFRA SLC5A7 LGI4 C1QTNF4

3.40e-041529740cb5f4dfae04e3f4eba502bbf229007d5fa3884d
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PDGFRA SLC5A7 LGI4 C1QTNF4

3.40e-04152974ba89ffb5a8bb33c188f854f54b39123b6d73496a
ToppCellE18.5-Immune-Immune_Myeloid-Monocytic-Macrophage-IM-IM_prolif|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

DAGLB SLC15A3 PIGZ SLC11A1

3.57e-0415497479ebda35dd1719e157738d7c13e5b8ccc3991f03
ToppCellmetastatic_Lymph_Node-Myeloid_cells-Alveolar_Mac|metastatic_Lymph_Node / Location, Cell class and cell subclass

CELA2B SLC15A3 SLC11A1 ADAMTSL4

3.66e-0415597403fd443740272dcb547e39deaf7ae89b8307f241
ToppCellPCW_13-14-Neuronal-Neuronal_SCP-neuro_proliferating_SCP1_(1)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

SLC5A7 SLC15A3 LGI4 TTLL7

3.75e-041569748353f98e7d393d4299ed1da8f66cfbc7176df1b5
ToppCellfrontal_cortex-Non-neuronal-astrocyte-Astro|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

KIRREL2 LGI4 FGFR3 SOD3

3.84e-041579740551442ae14685d8fe5729e3960c6324b1e05e4d
ToppCellfrontal_cortex-Non-neuronal-astrocyte|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

KIRREL2 LGI4 FGFR3 SOD3

3.84e-04157974803af734d7f775d294391e2b84e472a732e18cef
ToppCellfrontal_cortex-Non-neuronal-astrocyte-Astro-Astro_Aqp4|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

KIRREL2 LGI4 FGFR3 SOD3

3.84e-041579749aa5304a9704da6dd4eda7d6940494b00e38b2e8
ToppCellfacs-Trachea-3m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l1-41|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SYDE1 CLCN5 PCNX4 C15orf61

3.94e-041589746d2709b387945c015faa223c20d22b52a4082140
ToppCelldroplet-Lung-nan-21m-Myeloid-Intermediate_Monocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DAGLB MDM1 SLC11A1 ABCD1

4.13e-041609740b8151037b28f52a21918856a1e9336e8d5edb90
ToppCelldroplet-Lung-nan-21m-Myeloid-intermediate_monocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DAGLB MDM1 SLC11A1 ABCD1

4.13e-041609744738d0c73d8c3508e5b5beb6c61e0ad551d9b949
ToppCellControl-Mast_cells-Transitioning_MDM|Control / group, cell type (main and fine annotations)

CELA2B C15orf61 MMP11 SOD3

4.23e-041619745807ee48f871a3eb24ebf78fd107cf5f2a4ec846
ToppCellkidney_cells-Adult_normal_reference-Mesenchymal--glomerular_mesenchymal_cell-Renin-positive_Juxtaglomerular_Granular_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SLC5A7 LGI4 TTLL7 SOD3

4.32e-04162974c7114e24cb5525abb9780ca3d35dbcc4eabd4b64
ToppCellkidney_cells-Adult_normal_reference-Mesenchymal--glomerular_mesenchymal_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SLC5A7 LGI4 TTLL7 SOD3

4.32e-04162974f1851a173d3bcca2981d934161ec85d1cc0af5a2
ToppCellkidney_cells-Adult_normal_reference-Mesenchymal-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SLC5A7 LGI4 TTLL7 SOD3

4.32e-041629745d902bb31e691aea9749617cc88303c2448f24b8
ToppCell11.5-Distal-RBC|Distal / Age, Tissue, Lineage and Cell class

TF SLC20A2 SLC22A4 MPPED1

4.43e-04163974e9d814952d824539ff1dea119e4fca14a8c335a8
ToppCell11.5-Distal-RBC-RBC|Distal / Age, Tissue, Lineage and Cell class

TF SLC20A2 SLC22A4 MPPED1

4.43e-0416397431b60e065bac4ad380247964e7574f210106ebae
ToppCell368C-Fibroblasts-Fibroblast-B_(Myofibroblast)|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

ALDH8A1 PCDHA3 LGI4 GAL

4.53e-04164974dd29decc6c41a580cfdf03962827ec18d432935f
ToppCell368C-Fibroblasts-Fibroblast-B_(Myofibroblast)-|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

ALDH8A1 PCDHA3 LGI4 GAL

4.53e-04164974dcd3c3ee73900180451fad9b4de0efedbd375e1c
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-3m-Epithelial-neuronal_stem_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCC1 AMER1 SLC5A7 MPPED1

4.63e-041659741703d3eb644b3c743ad3c5532b1d29ea010c79c8
ToppCell3'-Parenchyma_lung-Epithelial-Neuro-endocrine/ionocytic-ionocyte-Ionocyte|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MFSD6L TXNRD2 MMP11 ESPL1

4.85e-0416797449d9220f22d10ff06c0512c9c40c26ad51728e4f
ToppCell5'-GW_trimst-1.5-LargeIntestine-Epithelial-epithelial_progenitor_cell-Distal_progenitor|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SLC17A4 CELA2B PIGZ FGFR3

4.85e-04167974720dc5855c856b478b5ca90156b30bfcc5518d60
ToppCell3'-Parenchyma_lung-Epithelial-Neuro-endocrine/ionocytic-ionocyte-Ionocyte-Ionocyte_L.0.7.0.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MFSD6L TXNRD2 MMP11 ESPL1

4.85e-041679747ec032a98a13504d15c7e3a4e259278d07f40180
ToppCell3'-Parenchyma_lung-Epithelial-Neuro-endocrine/ionocytic-ionocyte|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MFSD6L TXNRD2 MMP11 ESPL1

4.85e-041679745e3588eee73693a996bb4846427cf0038ceafbca
ToppCell3'-GW_trimst-1.5-LargeIntestine-Neuronal-Glial_immature-Differentiating_glia|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SLC15A3 LGI4 GJC3 TP53AIP1

4.85e-0416797417c653b46507c8bb85da95836ae72a6015336142
ToppCelldroplet-Kidney-nan-3m-Epithelial-Epcam____brush_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC9A8 SLC24A3 SLC22A7 MPPED1

4.85e-0416797440d102e01ccbc7262d00fafd59ca5234909009cb
ToppCelldroplet-Fat-Bat-18m-Myeloid-nan|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TXNRD2 CLCN7 AP5B1 ESPL1

4.96e-041689746fddc957a0503455d8c165862b5eb8e5fdb8a510
ToppCellChildren_(3_yrs)-Immune-enucleated_erythrocyte-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

FLT1 MDM1 MFSD6L FGFR4

4.96e-041689748f0c4dfad9f6fed9dcc31795abfe77758ceb46a1
ToppCelldroplet-Fat-Bat-18m-Myeloid-myeloid_cell|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TXNRD2 CLCN7 AP5B1 ESPL1

4.96e-04168974794035cb63353a7d02fd9939deb5b4d075c9d95a
ToppCelldroplet-Fat-Bat-18m-Myeloid|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TXNRD2 CLCN7 AP5B1 ESPL1

4.96e-041689741e23b634f96e88b976a523ca1f3fc08f6fe9b239
ToppCelldroplet-Liver-Npc-21m-Epithelial-nan|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MEGF8 FGFR4 SOD3

4.99e-0471973cf4c8715c2bd77fc86e45cc01bcc7aa6044e091d
ToppCell368C-Fibroblasts-Fibroblast-B_(Myofibroblast)|368C / Donor, Lineage, Cell class and subclass (all cells)

ALDH8A1 PCDHA3 LGI4 GAL

5.07e-041699741d5ce2c97f7ef7bdc9f861938077a9aa31d84db6
ToppCelldroplet-Heart-HEART_(LV+RV_ONLY)-30m-Hematologic-fibroblast|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCC1 MDM1 SLC11A1 SMIM33

5.07e-0416997415a9183c838cc6384d7f5dfeae3d30602964c9b3
ToppCellfacs-Aorta-Heart-24m-Mesenchymal-fibroblast_of_cardiac_tissue|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ALDH8A1 LTB4R2 KCNK7 GAL

5.07e-04169974daed9083ee05c220365200328c2c50047fe21efd
ToppCell368C-Fibroblasts-Fibroblast-B_(Myofibroblast)-|368C / Donor, Lineage, Cell class and subclass (all cells)

ALDH8A1 PCDHA3 LGI4 GAL

5.07e-0416997458098f8801ca941aeddafb47e88ab0df8b9edb57
ToppCelldroplet-Thymus-nan-18m-Myeloid-Macrophage|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MEGF8 IQCA1 FGFR3 SOD3

5.07e-041699744ac21e8199de4b6917eacadc56fffc6d886ee643
ToppCelltumor_Lymph_Node_/_Brain-Fibroblasts-COL13A1+_matrix_FBs|Fibroblasts / Location, Cell class and cell subclass

PDGFRA ABCA10 FLCN FGFR4

5.07e-0416997484b898a9fd8ced67c6a501d5cef6416f519902c4
ToppCelldroplet-Kidney-nan-21m-Myeloid-nan|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC15A3 SLC11A1 MMP11 ADAMTSL4

5.19e-04170974510625bd725d3590cffcd7acd1d42219f6eb1139
ToppCelldroplet-Kidney-nan-21m-Epithelial-brush_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC9A8 ALDH8A1 GALR2 SLC22A7

5.30e-04171974007f148f4611ea1826edfa9f91ced36541ad9f5a
ToppCellLPS-IL1RA-Epithelial_alveolar-Mes-like-AT2_Progenitor|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CACNA1B FLAD1 ANTKMT SLC22A31

5.30e-04171974ca2775a17b5c339c480a963953b6fa2b0731f24d
ToppCelldroplet-Kidney-nan-21m-Epithelial-Epcam____brush_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC9A8 ALDH8A1 GALR2 SLC22A7

5.30e-041719748e7223ba447947cdf4e1c82a52fd90439cf3d8f6
ToppCellLPS-IL1RA-Epithelial_alveolar-Mes-like|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CACNA1B FLAD1 ANTKMT SLC22A31

5.30e-041719743ad4f138d9570500cfb4423a2be16bb7d1cacbf8
ToppCelldroplet-Spleen-SPLEEN-30m-Hematologic-erythroblast|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TXNRD2 KIRREL2 MGST3 GHITM

5.54e-04173974a8fb8db6061fa4d8d56a7b45004ecbd344501573
ToppCell343B-Fibroblasts-Fibroblast-H-|343B / Donor, Lineage, Cell class and subclass (all cells)

AMER1 PDGFRA RGR ABCA10

5.66e-041749742627c3983009839fedbc5e3f628739dc026447f4
ToppCell3'-Airway_Nasal_SMG-Epithelial-Epithelial_transtional-secretory-SMG_mucus_secreting_cell-SMG_mucous-SMG_mucous_L.0.6.3.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PIGZ TF DNAJC10 GJC3

5.66e-04174974b1b54e4e23df8cfc04bf298d5c53de203a38b267
ToppCellP15-Mesenchymal-developing_mesenchymal_cell-mesenchymal_immature_unknown_1|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

PDGFRA SLC6A12 FGFR4 SOD3

5.66e-041749743c47d069bd836599a8d40eae485c23d4d3487517
ToppCell343B-Fibroblasts-Fibroblast-H|343B / Donor, Lineage, Cell class and subclass (all cells)

AMER1 PDGFRA RGR ABCA10

5.66e-04174974507a33e58f62e2b72f0bcc743e84dbd0bf705a15
ToppCellE16.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-SCMF-SCMF_mature|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PDGFRA PEX13 TXNRD2 CLCN5

5.78e-041759741d8aab491dcc27ea5dbfb6462d18ee280b21a05e
ToppCellPND03-Immune-Immune_Myeloid-Monocytic-Macrophage-IM-IM_mature|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

DAGLB SLC15A3 PIGZ SLC11A1

5.78e-0417597453e6f1f8dd482dfa2539e068dacefbb6e08443bc
ToppCell5'-GW_trimst-1.5-SmallIntestine-Epithelial-epithelial_progenitor_cell-Proximal_progenitor|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PIGZ SIAE FGFR3 STRC

5.78e-041759746759d200a133034756de9cdf2d5daceca927aac9
ToppCellE16.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-SCMF|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PDGFRA PEX13 TXNRD2 CLCN5

5.78e-04175974427a7ee92fe16a90625946492062d37aa0f7235b
ToppCellwk_15-18-Epithelial-PNS-COL20A1+_Schwann|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

LGI4 TTLL7 SSUH2 GJC3

6.03e-04177974b8cc6a7abf83a9844a5293b6cc4b19135b51fd53
ToppCell3'-GW_trimst-1.5-LargeIntestine-Neuronal-Glial_immature-Glia_3_(BCAN+)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ANKRD50 SLC15A3 LGI4 TF

6.03e-04177974d05497d2c80a66ec6a4e1733fea3a5534877a6a7
ToppCellPCW_13-14-Neuronal-Neuronal_postreplicative-neuro_NA|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

SLC5A7 LGI4 TTLL7 GAL

6.03e-041779748c78f7de091f16e86e326a73c9f1429e0232821f
ToppCellfacs-Kidney-nan-18m|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC9A8 ALDH8A1 SLC22A7 SOD3

6.03e-04177974d4cd54c07f1e51b5485270348fb7195d53465027
ToppCellPCW_13-14-Neuronal-Neuronal_SCP|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

SLC5A7 SLC15A3 LGI4 TTLL7

6.03e-04177974621dd82f1393c961d4dd7a615aa52c9df9e36336
ToppCellPCW_05-06-Neuronal-Neuronal_SCP-neuro_pre_proliferating_SCP_(4)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

SLC15A3 LGI4 TTLL7 GJC3

6.03e-0417797459726bfd98f656fdcedf448a7e2e76a9bfad8285
ToppCell(3)_Chondrocytes-(32)_Chondro-prehyper-2|World / Cell class and subclass of bone marrow stroma cells in homeostatis

SLC6A12 C1QTNF4 FGFR3 GJC3

6.16e-04178974c569a406c3ae183a278d8540e8eba58f4f26c5b0
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-kidney_interstitial_fibroblast_5|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PDGFRA SLC24A3 ABCA10 SLC22A31

6.16e-0417897478a0c6340001a77f5b2d890b6263f574af2e72da
ToppCelldroplet-Lung-30m-Hematologic-myeloid-classical_monocyte-classical_monocyte_l2-17-52|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

LTB4R2 SIAE DNAJC10 FLCN

6.29e-04179974af03705a783e77f75c44fdfa793cfdccbf9dd91c
Drugbumetanide

SLC46A2 SLC9A8 SLC5A7 SLC17A4 SLC22A7 CLCN5 CLCN7 SLC12A9 SLC20A2

1.92e-07209939CID000002471
DrugAC1L8Y60

SLC9A8 SLC17A4 CLCN5 CLCN7 SLC12A9 SLC20A2

1.75e-0689936CID000410009
DrugPyrvinium pamoate [3546-41-6]; Down 200; 3.4uM; MCF7; HT_HG-U133A

MDM1 SLC24A3 SYDE1 SLC12A9 FGFR3 ESPL1 PIGO

1.14e-051869373518_DN
Drug(9H-fluoren-9-yl)methyl(1-((6-(tert-butoxycarbonyl)amino-1-((4-methyl-2-oxo-1,2-dihydroquinolin-7-yl)amino)-1-oxohexan-2-yl)amino)-3-cyclohexyl-1-oxopropan-2-yl)carbamate

GALR2 GAL

1.65e-052932ctd:C552254
DrugDiphenylpyraline hydrochloride [132-18-3]; Up 200; 12.6uM; MCF7; HT_HG-U133A

SLC22A7 TTLL7 IQCA1 TECPR2 FLCN FGFR3 ADAMTSL4

1.76e-051999373640_UP
Diseasecerotoylcarnitine (C26) measurement

GALP GAL SLC22A4

8.75e-0613943EFO_0800542
Diseaseautosomal recessive nonsyndromic deafness 16 (implicated_via_orthology)

STRC STRCP1

1.00e-052942DOID:0110471 (implicated_via_orthology)
Diseasefemoral neck bone geometry

GALP GAL FGFR4

1.11e-0514943EFO_0004511
Diseaseserum metabolite measurement

ABCC1 ERAP1 CYP4A11 GALP SLC24A3 PSMD2 CELA2B GAL SLC6A12 SIAE SLC22A4 GHITM

4.65e-059459412EFO_0005653
DiseaseParaparesis, Spastic

TECPR2 ABCD1

6.00e-054942C0037771
Diseasebone disease (implicated_via_orthology)

FGFR3 FGFR4

9.98e-055942DOID:0080001 (implicated_via_orthology)
Disease3-hydroxysebacate measurement

CYP4A11 SLC17A4

9.98e-055942EFO_0800205
DiseaseAdrenomyeloneuropathy

PEX13 ABCD1

1.49e-046942C1527231
Diseaseosteopetrosis (implicated_via_orthology)

CLCN5 CLCN7

2.09e-047942DOID:13533 (implicated_via_orthology)
DiseaseAdrenoleukodystrophy

PEX13 ABCD1

2.09e-047942C0162309
DiseaseColorectal Neoplasms

ABCC1 ABCB6 ABCA10 FLCN FGFR3 MTDH

2.64e-04277946C0009404
DiseaseLeydig cell tumor (is_marker_for)

FLT1 PDGFRA

2.78e-048942DOID:2696 (is_marker_for)
Diseasecervix carcinoma (is_implicated_in)

ERAP1 FGFR3

4.44e-0410942DOID:2893 (is_implicated_in)
DiseaseAdenocarcinoma of lung (disorder)

FLT1 TF MRPS5 FGFR3 FGFR4

5.24e-04206945C0152013
Diseaseximenoylcarnitine (C26:1) measurement

GALP GAL

7.65e-0413942EFO_0800543
DiseaseSpastic Paraplegia, Hereditary

TECPR2 ABCD1

8.91e-0414942C0037773
DiseaseColorectal Carcinoma

ABCC1 ABCB6 ABCA10 FLCN FGFR3 MMP11 MTDH PIGO

1.82e-03702948C0009402
Diseasemetabolite measurement

ABCC1 CYP4A11 GALP SLC17A4 GAL SLC6A12 SLC22A4

2.11e-03560947EFO_0004725
DiseaseCleft Palate

AMER1 PDGFRA FGFR3

2.23e-0381943C0008925
DiseaseInvolutional paraphrenia

GALR2 GAL

2.87e-0325942C1571983
DiseasePsychosis, Involutional

GALR2 GAL

2.87e-0325942C1571984
DiseaseInvolutional Depression

GALR2 GAL

2.87e-0325942C0011574
DiseaseDepressive Symptoms

SLC5A7 TXNRD2

3.10e-0326942C0086132

Protein segments in the cluster

PeptideGeneStartEntry
PSIRGALVLGYEGWL

VDAC1

136

P21796
GVAGLISPWNLPLYL

ALDH8A1

146

Q9H2A2
LTDRGGPLGYQKILW

ADAMTSL4

491

Q6UY14
GFTVLYRQLPLSLGW

ABCA10

256

Q8WWZ4
GILLWEIFTLGGSPY

FGFR4

676

P22455
TVWLRLHGAPQYALG

C1QTNF4

131

Q9BXJ3
RFLAPWIGYGLLLLN

CYP4A11

121

Q02928
GYLWPRGSPALQLVV

ABCB6

251

Q9NP58
GLPWGVSSLPRYLGL

AMER1

861

Q5JTC6
IPGTLNGLYLWLCQR

ANKRD50

326

Q9ULJ7
GLLLHPGAYFRDLWN

CACNA1B

1206

Q00975
QLITLYGIWPLGSAA

IQCA1

546

Q86XH1
GLAAYAVWALLLQPG

ANTKMT

31

Q9BQD7
CGLRPAVGYELNPWL

ANTKMT

96

Q9BQD7
LPASGLGWLVDYGKL

ATF5

16

Q9Y2D1
LGVIWGVLPLRGFLG

RAB5IF

56

Q9BUV8
YGRSILTVPWVELGG

OSBPL9

561

Q96SU4
DGLRGLYQGVTPNIW

SLC25A32

76

Q9H2D1
LYQGVTPNIWGAGLS

SLC25A32

81

Q9H2D1
LFRILGGLWPTYGGV

ABCD1

516

P33897
YGILLWEIFSLGGTP

PDGFRA

881

P16234
PGAGSLRLLWAYVAQ

GJC3

126

Q8NFK1
WLSYELQPGTGGARI

PCDHA3

606

Q9Y5H8
YLINSWPFLLGKVRG

FLCN

181

Q8NFG4
SWGLRLYIPGFDVGT

ERVS71-1

206

P61550
GGPLLIRAAWYTAGI

GHITM

211

Q9H3K2
MGGLRPWSRYGLLVV

KCNK7

1

Q9Y2U2
PSLLIGAAWGRLFGI

CLCN7

516

P51798
LYLRQLGLAAPWVGT

MFSD6L

36

Q8IWD5
LTLIGRNPVGYPLAW

ERAP1

836

Q9NZ08
CGLGTWYLLPNRITL

PCNX4

151

Q63HM2
DEYSGRGIITWGLLP

MSTO1

251

Q9BUK6
GRKYPWAGLRSDQLG

MDM1

31

Q8TC05
GLGLPVALPARWAYA

MEGF8

1056

Q7Z7M0
FGPAALYIWAIGLLA

SLC11A1

356

P49279
TSIYGLLIGGEELWP

AP5M1

81

Q9H0R1
WAVLPLAGDYLRGLA

AP5B1

861

Q2VPB7
ASGLGLAWIVGRVLY

MGST3

86

O14880
YGWGFNLPRGQALLE

MPPED1

216

O15442
GLGLPWALQTLAVDY

SLC24A3

556

Q9HC58
SFWGSGLLYPVALLR

IGF2BP2-AS1

41

Q96M15
WLSYELQPGTGGARI

PCDHA4

606

Q9UN74
PARTLLLGWGPYAIL

RGR

216

P47804
RGGWTLNSAGYLLGP

GALP

31

Q9UBC7
IGLIWGLSLLFSGPY

GALR2

146

O43603
RYTEALLQGWLGAGP

ESPL1

2071

Q14674
YVTGWGRLQTNGALP

CELA2B

156

P08218
ILLHGLWYELFGGNP

DAGLB

526

Q8NCG7
PLWAQLGDLYGAIGS

FNIP1

501

Q8TF40
KRGWTLNSAGYLLGP

GAL

31

P22466
PFILLGIFGGLWGAL

CLCN5

391

P51795
PLWGGLSYIVSGSLS

MS4A18

191

Q3C1V0
RYPGWVILVGTGALG

MTDH

46

Q86UE4
LALGGQRDLPGWSRY

KIRREL2

61

Q6UWL6
DAYSLRIWGLGFLPQ

DNAJC10

656

Q8IXB1
GVLLWEIFTLGGSPY

FGFR3

681

P22607
RPLFGGLGGYWRALQ

FLAD1

76

Q8NFF5
LVTYALWAVGGPAGL

DNAJC22

6

Q8N4W6
LDGVWLSLPKLTYGG

SLC22A7

486

Q9Y694
LLLAGAQYLPGWTVL

SLC22A31

411

A6NKX4
GASYLLAPVGGWLAD

SLC15A3

81

Q8IY34
LAPVGGWLADVYLGR

SLC15A3

86

Q8IY34
LLAGGLLCQTIGWPY

SLC17A4

216

Q9Y2C5
IGPLVALWLIYKQGG

SLC20A2

511

Q08357
PRRYIIAAVLFWGGG

SLC22A4

396

Q9H015
YLLWLNLGPSVLAGV

ABCC1

456

P33527
LAWGFLGPRNSLYDL

MIGA1

541

Q8NAN2
PLEGLAGNLWLQDLY

MIEF2

321

Q96C03
VWRLRGGQLQPGYPA

MMP11

316

P24347
GLAWAQAPIGYSLSL

SLC5A7

81

Q9GZV3
PAALWGRLSLHLYGL

SYDE1

261

Q6ZW31
IIGEGRYGFLWPGLN

MRPS5

131

P82675
WILTGLGLGLSRPFL

TP53AIP1

81

Q9HCN2
LGPSLFVLAARLWGG

LGI4

276

Q8N135
ALLGLPGNGFVVWSL

LTB4R2

31

Q9NPC1
KDTYARWLPLGLGLN

PSMD2

551

Q13200
YVVSRPQPRGLLGWG

FAF2

81

Q96CS3
GEIIGLGNVWRFPYL

SLC6A12

51

P48065
DGGIYLIHWRVLGPQ

SMIM33

86

A0A1B0GW64
TLQYPIGLIASSWGG

SIAE

206

Q9HAT2
WFSGLRGAIPYALSL

SLC9A8

421

Q9Y2E8
LAQQGWLGLYRGMTP

SLC25A41

331

Q8N5S1
AVILGGPYLIWKLLS

PEX13

241

Q92968
GLTGNAVVLWLLGYR

MRGPRX4

41

Q96LA9
WGGLLRTVGAPLYAA

STRC

236

Q7RTU9
RLPSYDWLLQGGRGQ

SSUH2

31

Q9Y2M2
GIPTLLYGLGSWLFA

C15orf61

116

A6NNL5
GELPQALAWYHRALG

TTC24

131

A2A3L6
LGRSAGWNIPIGLLY

TF

141

P02787
FYQRAGLPSNVGLWG

SPEM2

206

Q0P670
LWRYRAGLAASLAGP

SOD3

156

P08294
GLRVLPQGYGWNLLY

SLC12A9

156

Q9BXP2
PQGYGWNLLYGSLLL

SLC12A9

161

Q9BXP2
GAPLLLGAGAIYLWS

TOMM70

46

O94826
ELWAVGPPGYLLQRL

TECPR2

1366

O15040
WPGLVSGYALLVGPR

PIGZ

116

Q86VD9
ALLGGLIQDAPNYGW

TXNRD2

101

Q9NNW7
GLSPLLSAYGLGWLS

SLC46A2

86

Q9BY10
PVAWGLVGAIAYAGL

PIGO

486

Q8TEQ8
WGGLLRTVGAPLYAA

STRCP1

236

A6NGW2
GVLLWEIFSLGGSPY

FLT1

1086

P17948
SLSGIGPDWGNSRYL

TTLL7

836

Q6ZT98