Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyCellularComponentsubapical complex

MPDZ PATJ

1.44e-045802GO:0035003
HumanPhenoAbnormal knee morphology

LIFR ARID1B CD247 TBX4 FBN2 GLI3 KAT6A TTI1 SIK3 COG5 NLRP3

4.91e-063643111HP:0034669
DomainL27_2

MPDZ PATJ

1.81e-052802PF09045
DomainL27_2

MPDZ PATJ

1.81e-052802IPR015132
DomainUBA

TDRD3 LATS1 SIK3

8.83e-0444803IPR015940
DomainUBA

TDRD3 LATS1 SIK3

1.07e-0347803PS50030
DomainL27

MPDZ PATJ

1.37e-0313802SM00569
DomainL27

MPDZ PATJ

1.37e-0313802PS51022
DomainL27_dom

MPDZ PATJ

1.37e-0313802IPR004172
DomainGal_mutarotase_SF_dom

GALM SI

2.36e-0317802IPR011013
DomainTF_T-box

EOMES TBX4

2.36e-0317802IPR001699
DomainTBOX

EOMES TBX4

2.36e-0317802SM00425
DomainTF_T-box_CS

EOMES TBX4

2.36e-0317802IPR018186
Domain-

EOMES TBX4

2.36e-03178022.60.40.820
DomainTBOX_3

EOMES TBX4

2.36e-0317802PS50252
DomainT-box

EOMES TBX4

2.36e-0317802PF00907
DomainTBOX_1

EOMES TBX4

2.36e-0317802PS01283
DomainTBOX_2

EOMES TBX4

2.36e-0317802PS01264
DomainUBA-like

TDRD3 LATS1 SPATS2L

2.61e-0364803IPR009060
Pubmed

OTUB2 Promotes Cancer Metastasis via Hippo-Independent Activation of YAP and TAZ.

LATS1 AMOT MPDZ PATJ SNRNP200 TP53BP2

7.52e-089181630472188
Pubmed

The RNF146 and tankyrase pathway maintains the junctional Crumbs complex through regulation of angiomotin.

AMOT MPDZ TNKS PATJ

1.93e-072281427521426
Pubmed

Cytokinesis involves a nontranscriptional function of the Hippo pathway effector YAP.

LATS1 MPDZ PATJ TP53BP2

2.34e-072381426933062
Pubmed

Molecular characterization of angiomotin/JEAP family proteins: interaction with MUPP1/Patj and their endogenous properties.

AMOT MPDZ PATJ

2.42e-07681317397395
Pubmed

The Crumbs complex couples cell density sensing to Hippo-dependent control of the TGF-β-SMAD pathway.

LATS1 AMOT MPDZ PATJ

3.33e-072581421145499
Pubmed

Deubiquitinating Enzyme USP9X Suppresses Tumor Growth via LATS Kinase and Core Components of the Hippo Pathway.

LATS1 AMOT MPDZ PATJ

3.92e-072681428720576
Pubmed

Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.

ZNF600 ARID1B WDR75 AMOT DZIP3 HIPK2 RNF38 SEC31A ZCCHC2 CUBN PATJ COG5 PUM1

1.29e-061084811311544199
Pubmed

A human MAP kinase interactome.

ZNF600 LATS1 KIAA1549L HIPK2 SEC31A SIK3 COG5 ZNF418 SNRNP200

2.02e-0648681920936779
Pubmed

BMP7 expression in mammalian cortical radial glial cells increases the length of the neurogenic period.

EOMES GLI3 SMAD1

4.35e-061481337300483
Pubmed

PATJ and MPDZ are required for trophectoderm lineage specification in early mouse embryos.

MPDZ PATJ

5.36e-06281237318097
Pubmed

A Significant Difference in Core PDZ Interactivity of SARS-CoV, SARS-CoV2 and MERS-CoV Protein E Peptide PDZ Motifs In Vitro.

MPDZ PATJ

5.36e-06281236932261
Pubmed

Nuclear Receptor Subfamily 1 Group D Member 1 Regulates Circadian Activity of NLRP3 Inflammasome to Reduce the Severity of Fulminant Hepatitis in Mice.

NR1D1 NLRP3

5.36e-06281229277561
Pubmed

The Amot/Patj/Syx signaling complex spatially controls RhoA GTPase activity in migrating endothelial cells.

AMOT MPDZ PATJ

6.67e-061681318824598
Pubmed

A Rich1/Amot complex regulates the Cdc42 GTPase and apical-polarity proteins in epithelial cells.

AMOT MPDZ PATJ

8.08e-061781316678097
Pubmed

Protein interaction network of the mammalian Hippo pathway reveals mechanisms of kinase-phosphatase interactions.

ARID1B LATS1 AMOT MPDZ R3HDM1 PATJ PUM1 TP53BP2

9.75e-0644681824255178
Pubmed

Functional proteomics mapping of a human signaling pathway.

TINAGL1 ARID1B TBX4 FBN2 ZFYVE9 UBR4 PUM1 SMAD1 TP53BP2

9.78e-0659181915231748
Pubmed

Isl1Cre reveals a common Bmp pathway in heart and limb development.

TBX4 GLI3 SMAD1

1.15e-051981316556916
Pubmed

Robust phosphoproteomic profiling of tyrosine phosphorylation sites from human T cells using immobilized metal affinity chromatography and tandem mass spectrometry.

CD247 LATS1 R3HDM1 USP6NL TP53BP2

1.54e-0513381515144186
Pubmed

Growth Hormone Receptor Deficiency Protects against Age-Related NLRP3 Inflammasome Activation and Immune Senescence.

GHR NLRP3

1.60e-05381226876170
Pubmed

Regulation of BMP4/Dpp retrotranslocation and signaling by deglycosylation.

NGLY1 SMAD1

1.60e-05381232720893
Pubmed

Tumor suppressor death-associated protein kinase is required for full IL-1β production.

DAPK1 NLRP3

1.60e-05381221041719
Pubmed

Distinct claudins and associated PDZ proteins form different autotypic tight junctions in myelinating Schwann cells.

MPDZ PATJ

1.60e-05381212403818
Pubmed

TP53, MSH4, and LATS1 germline mutations in a family with clustering of nervous system tumors.

LATS1 MSH4

1.60e-05381225041856
Pubmed

REV-ERBα integrates colon clock with experimental colitis through regulation of NF-κB/NLRP3 axis.

NR1D1 NLRP3

1.60e-05381230315268
Pubmed

DAPK1 may be a potential biomarker for arterial aneurysm in clinical treatment and activated inflammation levels in arterial aneurysm through NLRP3 inflammasome by Beclin1.

DAPK1 NLRP3

1.60e-05381234796763
Pubmed

Similar and distinct properties of MUPP1 and Patj, two homologous PDZ domain-containing tight-junction proteins.

MPDZ PATJ

1.60e-05381219255144
Pubmed

Knockdown of DAPK1 inhibits IL-1β-induced inflammation and cartilage degradation in human chondrocytes by modulating the PEDF-mediated NF-κB and NLRP3 inflammasome pathway.

DAPK1 NLRP3

1.60e-05381236412004
Pubmed

MPP3 is required for maintenance of the apical junctional complex, neuronal migration, and stratification in the developing cortex.

EOMES MPDZ PATJ

1.82e-052281323658188
Pubmed

Oscillating lncRNA Platr4 regulates NLRP3 inflammasome to ameliorate nonalcoholic steatohepatitis in mice.

NR1D1 NLRP3

3.20e-05481233391484
Pubmed

Downregulation of Grem1 expression in the distal limb mesoderm is a necessary precondition for phalanx development.

GLI3 SMAD1

3.20e-05481234719843
Pubmed

Amot130 adapts atrophin-1 interacting protein 4 to inhibit yes-associated protein signaling and cell growth.

LATS1 AMOT

3.20e-05481223564455
Pubmed

Aging Induces an Nlrp3 Inflammasome-Dependent Expansion of Adipose B Cells That Impairs Metabolic Homeostasis.

GHR NLRP3

3.20e-05481231735593
Pubmed

High-density association study of 383 candidate genes for volumetric BMD at the femoral neck and lumbar spine among older men.

GHR FZD7 LIFR TBX4 GLI3 NTRK1 SMAD1

3.21e-0538381719453261
Pubmed

Interaction proteome of human Hippo signaling: modular control of the co-activator YAP1.

LATS1 ZFYVE9 AMOT MPDZ PATJ TP53BP2

4.13e-0527081624366813
Pubmed

mTORC1 activity regulates post-translational modifications of glycine decarboxylase to modulate glycine metabolism and tumorigenesis.

AMOT BAG4 MPDZ R3HDM1 PATJ PUM1

4.48e-0527481634244482
Pubmed

Phosphorylation of angiomotin by Lats1/2 kinases inhibits F-actin binding, cell migration, and angiogenesis.

LATS1 AMOT

5.33e-05581224106267
Pubmed

Angiomotin binding-induced activation of Merlin/NF2 in the Hippo pathway.

LATS1 AMOT

5.33e-05581226045165
Pubmed

A tight junction-associated Merlin-angiomotin complex mediates Merlin's regulation of mitogenic signaling and tumor suppressive functions.

AMOT PATJ

5.33e-05581221481793
Pubmed

Carboxy-terminally truncated Gli3 proteins associate with Smads.

GLI3 SMAD1

5.33e-0558129843199
Pubmed

The leukemia inhibitory factor receptor (LIFR) gene is located within a cluster of cytokine receptor loci on mouse chromosome 15 and human chromosome 5p12-p13.

GHR LIFR

5.33e-0558128276403
Pubmed

The WW domains dictate isoform-specific regulation of YAP1 stability and pancreatic cancer cell malignancy.

LATS1 AMOT

5.33e-05581232292505
Pubmed

Proteome-scale mapping of binding sites in the unstructured regions of the human proteome.

LATS1 UBR4 RNF38 TNKS PATJ SMAD1 TP53BP2

6.66e-0543081735044719
Pubmed

Interaction of Brn3a and HIPK2 mediates transcriptional repression of sensory neuron survival.

NTRK1 HIPK2

7.99e-05681215492043
Pubmed

Developmental and regional expression and localization of mRNAs encoding proteins involved in RNA translocation.

SI PUM1

7.99e-05681216009965
Pubmed

Counter-Balance Between Gli3 and miR-7 Is Required for Proper Morphogenesis and Size Control of the Mouse Brain.

EOMES GLI3

7.99e-05681230210296
Pubmed

Serum deprivation inhibits the transcriptional co-activator YAP and cell growth via phosphorylation of the 130-kDa isoform of Angiomotin by the LATS1/2 protein kinases.

LATS1 AMOT

7.99e-05681224101513
Pubmed

In vivo convergence of BMP and MAPK signaling pathways: impact of differential Smad1 phosphorylation on development and homeostasis.

EOMES SMAD1

7.99e-05681215198985
Pubmed

Angiomotins stimulate LATS kinase autophosphorylation and act as scaffolds that promote Hippo signaling.

LATS1 AMOT

7.99e-05681230266805
Pubmed

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

TDRD3 UBR4 DZIP3 MPDZ DAPK1 TNKS SEC31A SIK3 RAI1 TP53BP2

8.03e-05963811028671696
Pubmed

A SMAD1/5-YAP signalling module drives radial glia self-amplification and growth of the developing cerebral cortex.

EOMES ISLR2 SMAD1

9.68e-053881332541003
Pubmed

UTX Affects Neural Stem Cell Proliferation and Differentiation through PTEN Signaling.

EOMES UTY

1.12e-04781229551674
Pubmed

Egr-1 and Hipk2 are required for the TrkA to p75(NTR) switch that occurs downstream of IGF1-R.

NTRK1 HIPK2

1.12e-04781218378044
Pubmed

Pals1/Mpp5 is required for correct localization of Crb1 at the subapical region in polarized Muller glia cells.

MPDZ PATJ

1.12e-04781216885194
Pubmed

BMP7 and SHH regulate Pax2 in mouse retinal astrocytes by relieving TLX repression.

GLI3 SMAD1

1.12e-04781219505455
Pubmed

Requirement of the co-repressor homeodomain-interacting protein kinase 2 for ski-mediated inhibition of bone morphogenetic protein-induced transcriptional activation.

HIPK2 SMAD1

1.12e-04781212874272
Pubmed

Hgs (Hrs), a FYVE domain protein, is involved in Smad signaling through cooperation with SARA.

ZFYVE9 SMAD1

1.12e-04781211094085
Pubmed

Actin-binding and cell proliferation activities of angiomotin family members are regulated by Hippo pathway-mediated phosphorylation.

LATS1 AMOT

1.12e-04781224225952
Pubmed

Citron kinase interacts with LATS2 and inhibits its activity by occluding its hydrophobic phosphorylation motif.

LATS1 MPDZ PATJ

1.13e-044081330865227
Pubmed

Differential expression of ZAP-70 and Syk protein tyrosine kinases, and the role of this family of protein tyrosine kinases in TCR signaling.

CD247 KCNN2

1.49e-0488128176201
Pubmed

Isl1 mediates mesenchymal expansion in the developing external genitalia via regulation of Bmp4, Fgf10 and Wnt5a.

TBX4 SMAD1

1.49e-04881229126155
Pubmed

Differential roles of ARID1B in excitatory and inhibitory neural progenitors in the developing cortex.

EOMES ARID1B

1.49e-04881233594090
Pubmed

Adamts17 is involved in skeletogenesis through modulation of BMP-Smad1/5/8 pathway.

FBN2 SMAD1

1.49e-04881231201465
Pubmed

Merlin/NF2 loss-driven tumorigenesis linked to CRL4(DCAF1)-mediated inhibition of the hippo pathway kinases Lats1 and 2 in the nucleus.

LATS1 AMOT

1.49e-04881225026211
Pubmed

A combined analysis of genomic and primary protein structure defines the phylogenetic relationship of new members if the T-box family.

EOMES TBX4

1.49e-0488129503012
Pubmed

Asymmetric distribution of CRUMBS polarity complex proteins from compacted 8-cell to blastocyst stage during mouse preimplantation development.

MPDZ PATJ

1.49e-04881229155075
Pubmed

Genome-wide association study identifies ALLC polymorphisms correlated with FEV₁ change by corticosteroid.

ALLC TNKS

1.49e-04881224792382
Pubmed

UTX deficiency in neural stem/progenitor cells results in impaired neural development, fetal ventriculomegaly, and postnatal death.

EOMES UTY

1.49e-04881236412518
Pubmed

Characterizing WW domain interactions of tumor suppressor WWOX reveals its association with multiprotein networks.

TDRD3 AMOT MPDZ SNRNP200 USP6NL

1.68e-0422081524550385
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

LATS1 AMOT MPDZ SIK3 R3HDM1 PATJ PUM1 USP6NL TP53BP2

1.78e-0486181936931259
Pubmed

Acquisition of neural fate by combination of BMP blockade and chromatin modification.

SMAD1 PHC1

1.91e-04981237771660
Pubmed

The BAF chromatin complex component SMARCC1 does not mediate GLI transcriptional repression of Hedgehog target genes in limb buds.

ARID1B GLI3

1.91e-04981237805104
Pubmed

Loss of Suppressor of Fused in Mid-Corticogenesis Leads to the Expansion of Intermediate Progenitors.

EOMES GLI3

1.91e-04981228781964
Pubmed

Bone morphology is regulated modularly by global and regional genetic programs.

GLI3 SMAD1

1.91e-04981231221640
Pubmed

Combinatorial Smad2/3 Activities Downstream of Nodal Signaling Maintain Embryonic/Extra-Embryonic Cell Identities during Lineage Priming.

EOMES SMAD1

1.91e-04981230134160
Pubmed

The Transcription Factor OVOL2 Represses ID2 and Drives Differentiation of Trophoblast Stem Cells and Placental Development in Mice.

EOMES GCM1

1.91e-04981232244352
Pubmed

Disrupting Hedgehog signaling in melanocytes by SUFU knockout leads to ocular melanocytosis and anterior segment malformation.

GLI3 SMAD1

2.38e-041081237577930
Pubmed

AMPK modulates Hippo pathway activity to regulate energy homeostasis.

LATS1 TP53BP2

2.38e-041081225751139
Pubmed

NEDD4L-mediated Merlin ubiquitination facilitates Hippo pathway activation.

LATS1 AMOT

2.38e-041081233058421
Pubmed

Mouse embryos lacking Smad1 signals display defects in extra-embryonic tissues and germ cell formation.

EOMES SMAD1

2.38e-041081211566864
Pubmed

Characterization of a novel gene adjacent to PAX6, revealing synteny conservation with functional significance.

KIAA1549L MPPED2

2.38e-041081211889558
Pubmed

Evidence for an early role for BMP4 signaling in thymus and parathyroid morphogenesis.

GCM1 SMAD1

2.38e-041081220043899
Pubmed

Pitx1 determines the morphology of muscle, tendon, and bones of the hindlimb.

TBX4 GLI3

2.38e-041081216989801
Pubmed

Myh10 deficiency leads to defective extracellular matrix remodeling and pulmonary disease.

TBX4 FBN2 GLI3

2.48e-045281330389913
Pubmed

Gli3 is required for maintenance and fate specification of cortical progenitors.

EOMES GLI3

2.91e-041181221525285
Pubmed

The ubiquitin ligase STUB1 regulates stability and activity of RUNX1 and RUNX1-RUNX1T1.

DZIP3 RNF38

2.91e-041181228536267
Pubmed

Endofin acts as a Smad anchor for receptor activation in BMP signaling.

ZFYVE9 SMAD1

2.91e-041181217356069
Pubmed

Syncytin-A knockout mice demonstrate the critical role in placentation of a fusogenic, endogenous retrovirus-derived, envelope gene.

EOMES GCM1

2.91e-041181219564597
Pubmed

A pair of co-opted retroviral envelope syncytin genes is required for formation of the two-layered murine placental syncytiotrophoblast.

EOMES GCM1

2.91e-041181222032925
Pubmed

SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.

ARID1B LATS1 AMOT MPDZ PATJ SNRNP200 TP53BP2

2.98e-0454981738280479
Pubmed

SPOP targets oncogenic protein ZBTB3 for destruction to suppress endometrial cancer.

GLI3 HIPK2

3.48e-041281231911863
Pubmed

Unfolded protein response, activated by OASIS family transcription factors, promotes astrocyte differentiation.

GCM1 SMAD1

3.48e-041281222828627
Pubmed

Gli3 controls the onset of cortical neurogenesis by regulating the radial glial cell cycle through Cdk6 expression.

EOMES GLI3

3.48e-041281230093555
Pubmed

K33-linked polyubiquitination of Zap70 by Nrdp1 controls CD8(+) T cell activation.

EOMES CD247

3.48e-041281226390156
Pubmed

SNIP1 Recruits TET2 to Regulate c-MYC Target Genes and Cellular DNA Damage Response.

WDR75 SNRNP200 SMAD1 RAI1 PHC1

3.56e-0425981530404004
Pubmed

RNF43 inhibits WNT5A-driven signaling and suppresses melanoma invasion and resistance to the targeted therapy.

AMOT GLI3 R3HDM1 USP6NL TP53BP2

3.82e-0426381534702444
Pubmed

Human Pumilio-2 is expressed in embryonic stem cells and germ cells and interacts with DAZ (Deleted in AZoospermia) and DAZ-like proteins.

DZIP3 PUM1

4.11e-041381212511597
Pubmed

Embryonic stromal clones reveal developmental regulators of definitive hematopoietic stem cells.

NTRK1 SMAD1

4.11e-041381218087045
Pubmed

Analysis of transcription factors expressed at the anterior mouse limb bud.

EOMES GLI3

4.11e-041381228467430
Pubmed

Deterministic and stochastic allele specific gene expression in single mouse blastomeres.

EOMES FZD7 GLI3 KAT6A SMAD1 PHC1

4.76e-0442481621731673
Pubmed

Reduced BMP signaling results in hindlimb fusion with lethal pelvic/urogenital organ aplasia: a new mouse model of sirenomelia.

TBX4 SMAD1

4.79e-041481223028455
InteractionRASSF8 interactions

ARID1B LATS1 AMOT MPDZ TP53BP2

3.28e-0591815int:RASSF8
InteractionWWC1 interactions

LATS1 AMOT MPDZ PATJ USP6NL

3.84e-0594815int:WWC1
InteractionAMOTL1 interactions

LATS1 AMOT MPDZ TNKS PATJ

4.04e-0595815int:AMOTL1
InteractionARHGAP17 interactions

AMOT NTRK1 SEC31A PATJ NLRP3

4.47e-0597815int:ARHGAP17
InteractionOTUD4 interactions

TDRD3 LATS1 RPTN GLI3 ZCCHC2 R3HDM1 PUM1

4.60e-05236817int:OTUD4
InteractionRUNX1 interactions

BAG4 KAT6A DZIP3 HIPK2 RNF38 MPPED2 SMAD1 PHC1

4.75e-05324818int:RUNX1
Cytoband5p13-p12

GHR LIFR

9.21e-0638125p13-p12
Cytoband1p35.2

TINAGL1 PUM1

3.63e-04168121p35.2
Cytoband19q13.41

ZNF600 ZNF321P ZNF808

3.66e-047881319q13.41
GeneFamilyPDZ domain containing|Crumbs complex

MPDZ PATJ

3.23e-0495521223
GeneFamilyT-boxes

EOMES TBX4

1.35e-0318552766
CoexpressionBROWNE_HCMV_INFECTION_1HR_DN

ZFYVE9 AMOT HIPK2 CUBN MPPED2 UTY GABBR1

5.16e-06218817M9802
ToppCellMesenchymal_cells-Adipo-CAR|World / Lineage and Cell class

GHR LIFR PODNL1 ANGPTL4 MPDZ DAPK1

1.16e-061868166ca8ce7ced91d6308b7c056032ffec1b37c974bf
ToppCellrenal_medulla_nuclei|World / Celltypes from Cells and Nuclei per compartment and clinical group

ARID1B DAPK1 SIK3 PATJ MPPED2 UTY

1.27e-06189816830d9cd0dd706bce22eb2416f07b2c31c870a05a
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

TINAGL1 LIFR FBN2 AMOT GCM1 DAPK1

1.48e-061948168ddcaaf24cee6e30d5be52c0cbf778cfba309c53
ToppCellStriatum-Neuronal-Inhibitory-iN2(Gad1Gad2)-Chat-Inhibitory_Neuron.Gad1Gad2-Chat-Slc17a8.Chat_(cholinergic_interneuron)|Striatum / BrainAtlas - Mouse McCarroll V32

PODNL1 NTRK1 MSH4 CUBN

1.13e-05768143073a8ace46ad18bddd22ec8f3a1b59ee2fd989d
ToppCellStriatum-Neuronal-Inhibitory-iN2(Gad1Gad2)-Chat-Inhibitory_Neuron.Gad1Gad2-Chat-Slc17a8.Chat_(cholinergic_interneuron)-|Striatum / BrainAtlas - Mouse McCarroll V32

PODNL1 NTRK1 MSH4 CUBN

1.13e-05768143f5865b9cb6648b88eb873018e513c5efb457ae5
ToppCellStriatum-Neuronal-Inhibitory-iN2(Gad1Gad2)-Chat|Striatum / BrainAtlas - Mouse McCarroll V32

PODNL1 NTRK1 MSH4 CUBN

1.13e-0576814041a8984b3ae4bb03ae6db8234c1333ac73098fa
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CFAP54 FBN2 TRPC3 GCM1 DAPK1

1.70e-05175815284fdc7a9d303636a637041846850d19d114861a
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD|renal_cortex_nuclei / Celltypes from Cells and Nuclei per compartment and clinical group

ALLC GALM ACSF2 CUBN PATJ

1.99e-05181815c80ffa2ded5975a88e9a1a7d333196f95237bf0a
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

LIFR CFAP54 FBN2 TRPC3 DAPK1

2.27e-051868155c4ffe4e4d5536ae9f8794277fe032c693e7dd56
ToppCellPCW_07-8.5-Mesenchymal-Mesenchymal_fibroblastic-mes_immature3_(17)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

GHR LIFR TBX4 GLI3 TRPC3

2.33e-05187815a9316e2818217ec5feae9cf8816f7249803caee6
ToppCell-Unknown-Endothelial-Myofibroblast| / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

LATS1 ZFYVE9 WDR75 ZNF268 RNF38

2.39e-051888156468fa95ad0395395301115286f2d8c0df5d3882
ToppCell-Unknown-Endothelial| / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

LATS1 ZFYVE9 WDR75 ZNF268 RNF38

2.39e-051888157a81ac5c79c3eb26639b52d2b9fd5e7ef9798fd6
ToppCell-Unknown| / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

LATS1 ZFYVE9 WDR75 ZNF268 RNF38

2.39e-051888159cb718bfe1358c6fd842f096e228eb0abb9aefc6
ToppCell(1)_Control_(PBS)-(3)_LEPR+_perivascular_cells|World / Stress and Cell class

GHR LIFR PODNL1 MPDZ DAPK1

2.52e-05190815ec0ab31266583a0966ac7615d5c0fabb7b7e66e8
ToppCelldroplet-Pancreas-Endocrine-21m-Mesenchymal-pancreatic_stellate_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SPATS2L PCDHGB2 GLI3 NTRK1 ANGPTL4

2.71e-0519381559b8186d0221fba06a16157e9d148399ed801f38
ToppCelldroplet-Pancreas-Endocrine-21m-Mesenchymal-pancreatic_stellate_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SPATS2L PCDHGB2 GLI3 NTRK1 ANGPTL4

2.71e-05193815dc92680b4bb9fc26430c92e03adb839c8c3b3b98
ToppCelldroplet-Pancreas-Endocrine-21m-Mesenchymal|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SPATS2L PCDHGB2 GLI3 NTRK1 ANGPTL4

2.71e-0519381503678162648bd5b1d65a5450b60c8863edbf95c7
ToppCellControl-MAIT|Control / Disease condition and Cell class

EOMES SPATS2L GALM NR1D1 MPPED2

2.78e-05194815ed99f8bff6766795fc396990604366f49ff58181
ToppCellTracheal-NucSeq|Tracheal / Cell types per location group and 10X technology with lineage, and cell group designations

ARID1B TNKS SIK3 COG5 UTY

3.14e-0519981594b94b17ca18b8dc27b91da1f2ccf89e03cc7035
ToppCellBrain_organoid-organoid_Paulsen_bioRxiv-1_mon-Proliferating-Cycling_Progenitors|1_mon / Sample Type, Dataset, Time_group, and Cell type.

FZD7 GLI3 HIPK2 MPDZ DAPK1

3.14e-05199815358c4b3037f59378db8916a2fbe9ed4830cf1449
ToppCellControl-Control-Lymphocyte-T/NK-MAIT|Control / Disease, condition lineage and cell class

EOMES CD247 GALM NR1D1 MPPED2

3.22e-05200815888a8045e0457cd9d0c570360cca20a6efb44f13
ToppCelldroplet-Skin-nan-18m-Epithelial-basal_cell_of_epidermis|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TINAGL1 ANGPTL4 PLA2G4E UTY

5.22e-0511281432c6ab8e9b71c6c3df7e3e119b88e6ad1b895d50
ToppCellEntopeduncular-Macroglia-ASTROCYTE|Entopeduncular / BrainAtlas - Mouse McCarroll V32

GALM GLI3 AK9 ACSF2

9.05e-05129814c37bdd6c0b2944fbfa064922954ea0e263160e2a
ToppCellEntopeduncular-Macroglia-ASTROCYTE-Gja1|Entopeduncular / BrainAtlas - Mouse McCarroll V32

GALM GLI3 AK9 ACSF2

9.05e-051298148648ae59f7aca0f5b4983bdb4a65b03b2ca761e1
ToppCellPBMC_fresh-frozen-Severe-critical_convalescent_d14-21-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c09-SLC4A10|Severe-critical_convalescent_d14-21 / Compartment, severity and other cell annotations on 10x 3' data (130k)

EOMES TBX4 KCNN2 NR1D1

1.79e-04154814e94cd11488003347120eacd3ced0a8923ed09ccc
ToppCellfacs-Heart-RA-24m-Lymphocytic-T_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EOMES PODNL1 CD247 GCM1

1.83e-04155814cc3fc379ea78742a216317054f336331f7c7a157
ToppCellfacs-Heart-RA-24m-Lymphocytic-T_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EOMES PODNL1 CD247 GCM1

1.83e-041558141900a76754e2a9c7117e531c5907b7942f72c4a6
ToppCell368C-Endothelial_cells-Endothelial-E|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)

CD247 GALM SIK3 ZNF418

1.88e-041568144877aabf647238c0279e497345b6a6d5ee07ef9c
ToppCell368C-Endothelial_cells-Endothelial-E-|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)

CD247 GALM SIK3 ZNF418

1.88e-041568141d681fa17e62815f5d5f90c86be3c248b38e011b
ToppCellChildren_(3_yrs)-Epithelial-basal_cell-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

TINAGL1 CDH26 PATJ MPPED2

1.93e-041578146ee2692f705bdd93ba523dffaf2f0cd921b47e28
ToppCellPND28-Immune-Immune_Myeloid-Monocytic-Macrophage-AM-AM_mature|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

DAPK1 CUBN ZNF418 NR1D1

1.97e-041588146811dc4f101dfa9a9cc13d949760d43aa522bf3b
ToppCellfacs-Marrow-B-cells-3m-Lymphocytic-BM_CD8_+_CD4_T_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EOMES TDRD3 CD247 PATJ

2.07e-0416081455f599df6e3b7a5a505df4b094c834281311d94a
ToppCellfacs-Marrow-B-cells-3m-Lymphocytic-mature_alpha-beta_T_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EOMES TDRD3 CD247 PATJ

2.07e-04160814296e53e1e0786346d38db2d4188b9a1c0430627b
ToppCellTCGA-Brain-Primary_Tumor-Low_Grade_Glioma-Oligoastrocytoma|TCGA-Brain / Sample_Type by Project: Shred V9

HIPK2 DAPK1 CARD14 GABBR1

2.12e-04161814347edb0de10850b7d16c40945751033289289c9b
ToppCellsystemic_lupus_erythematosus-flare-Lymphocytic_T-CytoT_GZMK+-male|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

EOMES PODNL1 ANGPTL4 UTY

2.17e-0416281419395bdb282b4a2d88cd33191af12c24a88c3d16
ToppCellfacs-Marrow-T-cells-24m-Lymphocytic-mature_alpha-beta_T_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EOMES PODNL1 CFAP54 CD247

2.17e-04162814b5b2cdbcc5bbfab52cc7d8a5504d34bb2e73771a
ToppCellPND28-Immune-Immune_Myeloid-Monocytic-Macrophage-AM|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

DAPK1 CUBN ZNF418 NR1D1

2.17e-04162814d712bc31840ad1523e3dbf884acbb428a8995001
ToppCellfacs-Marrow-T-cells-24m-Lymphocytic-BM_CD8_+_CD4_T_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EOMES PODNL1 CFAP54 CD247

2.17e-041628144f9cf67b4b00b1cf78eeb9be1c701d535021a61d
ToppCellHealthy-NK_CD56bright|Healthy / disease group, cell group and cell class

EOMES CD247 DZIP3 GOLIM4

2.28e-04164814ed193211965accba60a256d3e6c159f0fc911d8b
ToppCell356C-Fibroblasts-Fibroblast-D|356C / Donor, Lineage, Cell class and subclass (all cells)

AMOT GLI3 ANGPTL4 MSH4

2.38e-041668147286a37b2827f3747469ffd0d76cbe81116db7ee
ToppCell356C-Fibroblasts-Fibroblast-D-|356C / Donor, Lineage, Cell class and subclass (all cells)

AMOT GLI3 ANGPTL4 MSH4

2.38e-041668147c2eee0a4f45795a956acf936b85bdb35f1b1624
ToppCellHealthy-NK_CD56bright|World / disease group, cell group and cell class

EOMES ZNF600 CD247 DZIP3

2.44e-04167814ab7a570a75ee2018b9fe886cdec79cda27f1563f
ToppCell367C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_0.5|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

CDH26 CD247 HIPK2 MUC4

2.44e-04167814e242827999caad08b0894d88ab97bc1df41b7650
ToppCelldroplet-Trachea-3m-Mesenchymal-fibroblast-fibroblast_of_trachea-|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

TINAGL1 LIFR FBN2 COG5

2.44e-04167814774f3264318b002d0df5d06d41d645366038d0bf
ToppCelldroplet-Marrow-nan-3m-Myeloid-basophil|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ISLR2 XPNPEP3 KAT6A R3HDM1

2.55e-041698145f5bec13208f4c3b6eacbba180c8a6402743b76e
ToppCellCOVID-19_Moderate-NK_CD56bright|World / disease group, cell group and cell class

EOMES CD247 DZIP3 GOLIM4

2.61e-04170814caa6a534c1e9639caced9a51680f5c905f061bcc
ToppCellControl-Epithelial_cells-Airway_basal|Control / group, cell type (main and fine annotations)

CDH26 GLI3 MPPED2 MUC4

2.67e-041718143965ced4be6db14265a90673502fceee425837ca
ToppCellfacs-Marrow-B-cells-18m-Lymphocytic-BM_CD4_T_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PODNL1 CD247 CUBN COG5

2.67e-041718146f49537f8d3cf18e65aa999fec32ed347ce2da3e
ToppCellfacs-Marrow-B-cells-18m-Lymphocytic-CD4-positive,_alpha-beta_T_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PODNL1 CD247 CUBN COG5

2.67e-04171814ab97ae2b127a585f170f028f1c475cdd1b0cdea5
ToppCellMultiple_Sclerosis-Lymphocyte-T_NK-MAIT|Multiple_Sclerosis / Disease, Lineage and Cell Type

EOMES SPATS2L NR1D1 MPPED2

2.73e-0417281418bda0038cb37da6784e7bf7291272c108cfd9c5
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_ILC|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

EOMES LIFR CD247 HIPK2

2.73e-0417281486f52f486d67217fc1b8443ab362c975df2974a4
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_ILC-NK_cell-NK_c01-FCGR3A|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

EOMES LIFR CD247 HIPK2

2.73e-04172814fb2df8fea6df5947165f13978f1d1006d15b60fd
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_ILC-NK_cell|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

EOMES LIFR CD247 HIPK2

2.73e-04172814e38ebb216e4ddcd008148fcbaf709b4f3c83706a
ToppCellfacs-Trachea-nan-24m-Epithelial-ciliated_columnar_cell_of_tracheobronchial_tree|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CDH26 CFAP54 RPTN MUC4

2.79e-0417381427ae126c720f20d1fe116abbcd358e4cff8baf6b
ToppCell343B-Lymphocytic-NK_cells-NK_cell_E|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

SPATS2L TTI1 PATJ NLRP3

2.85e-04174814a1f745962a104c6f4b86b7e482da8755384c773a
ToppCell5'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-club_cell-Club_(non-nasal)|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

GHR AMOT MPPED2 MUC4

2.85e-0417481442f2ba54b4ea4c62482582b0ccdadffae0a5eb4a
ToppCellPBMC-Severe-Lymphocyte-T/NK-NK_cell-NK_CD56bright-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

EOMES ZNF600 CD247 GOLIM4

2.91e-041758140ed053aa8353c72ff37fee830672704a3ddc7d85
ToppCellPBMC-Severe-Lymphocyte-T/NK-NK_cell-NK_CD56bright|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

EOMES ZNF600 CD247 GOLIM4

2.91e-041758140124a3c4696b39cee8b566e94603d1d3d128bfa5
ToppCellPBMC-Severe-Lymphocyte-T/NK-NK_cell-NK_CD56bright|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

EOMES ZNF600 CD247 GOLIM4

2.91e-04175814e219b61d6bc078d44ea7d06191d3462654d857a1
ToppCell343B-Lymphocytic-NK_cells-NK_cell_E|NK_cells / Donor, Lineage, Cell class and subclass (all cells)

SPATS2L TTI1 PATJ NLRP3

2.91e-0417581478a86cac3e6c0d115c997d1c29ee0e24af54551f
ToppCellPBMC-Severe-Lymphocyte-T/NK-NK_cell-NK_CD56bright-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

EOMES ZNF600 CD247 GOLIM4

2.91e-04175814bd16c80418bf71127e6f1e50edf83967c9218b42
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CFAP54 FBN2 HIPK2 DAPK1

2.98e-04176814327a3e81b724252e36d786de92a3ffd721ea6d7b
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_3|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ALLC GALM ACSF2 CUBN

2.98e-041768141595dbeee336a81e581325d63208ec6262664ee9
ToppCellCV-Severe-7|Severe / Virus stimulation, Condition and Cluster

TRPC3 TNKS UTY HSF5

3.04e-0417781482fdd6185b368f54f03de389427cbe3071d21a99
ToppCell3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.0.5|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CDH26 PATJ MUC4 RAI1

3.17e-041798146e965e424eebef50f0202cff75f458be395cfca1
ToppCellfacs-Lung-nan-3m-Mesenchymal-Pericyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TBX4 TRPC3 ANGPTL4 KCNN2

3.17e-041798147078022e60faa86444f2a2c6eb9f767cc66b5cfa
ToppCellfacs-Lung-nan-3m-Mesenchymal-pericyte_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TBX4 TRPC3 ANGPTL4 KCNN2

3.17e-04179814d4a975d8ffa5e77fb5c0ec05bf9c8f843c77ce07
ToppCellChildren_(3_yrs)-Mesenchymal-pericyte_cell-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

TINAGL1 GHR TBX4 TRPC3

3.31e-04181814451b87ac95154bb80018b8dd245b4a6389d81411
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CFAP54 FBN2 TRPC3 DAPK1

3.31e-041818146956ecd6264f7469a25e555673bce4eb97d28f7a
ToppCellMesenchymal_cells-Adipo-CAR|Mesenchymal_cells / Lineage and Cell class

GHR LIFR PODNL1 ANGPTL4

3.31e-041818141cfb03eb03a37b036b4eeacec69c9b8163af1ee4
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_C_(IT_L4_RORB)-Exc_L2-4_RORB_GRIK1|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SPATS2L TRPC3 DAPK1 R3HDM1

3.31e-0418181457994ff4ecffb15653aee00644d9f887f5e3461d
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CFAP54 FBN2 TRPC3 DAPK1

3.38e-041828145e1b316599436740f1b30875f0ebd33c3edfb2b6
ToppCellTCGA-Lung-Primary_Tumor-Lung_Carcinoma-Lung_Squamous_Cell_Carcinoma-3|TCGA-Lung / Sample_Type by Project: Shred V9

FZD7 FBN2 KIAA1549L GOLIM4

3.52e-04184814ea4ccebe2d54279fcc517e4f0bfa652b91a808bb
ToppCellCV-Healthy-7|CV / Virus stimulation, Condition and Cluster

ZNF268 XPNPEP3 USP6NL RAI1

3.52e-041848140e5cc77aaa73ceb791f8be7456177577fd2e5586
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.0.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CFAP54 CATSPERE DZIP3 AK9

3.52e-041848142df903924df9cb71039159416bcbe6a6614e21fe
ToppCelldroplet-Spleen-SPLEEN-1m-Lymphocytic-mature_NK_T_cell|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EOMES PODNL1 CD247 MSH4

3.52e-041848148095be57ed189763b5be039f330149a41e5b406a
ToppCellPBMC-Mild-Lymphocyte-T/NK-NK_cell-NK_CD56bright-|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

EOMES ZNF600 CD247 GOLIM4

3.60e-041858143a046c948524e5d0e986cd645e318d6930d7e0ee
ToppCellPBMC-Mild-Lymphocyte-T/NK-NK_cell-NK_CD56bright|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)

EOMES ZNF600 CD247 GOLIM4

3.60e-0418581471d1a771026d9fa3528d46ac3d11353e396f2d87
ToppCellpdx-Tumor_cells-T0|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)

SPATS2L DAPK1 PUM1 ITIH2

3.60e-041858141d874608aa2062024323512f68889219471b2f00
ToppCellPBMC-Mild-Lymphocyte-T/NK-NK_cell-NK_CD56bright-|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

EOMES ZNF600 CD247 GOLIM4

3.60e-0418581437b48218dd523049b57b13eb9cdb34e106cf91ea
ToppCellCV-Healthy-7|Healthy / Virus stimulation, Condition and Cluster

ZNF268 XPNPEP3 USP6NL RAI1

3.60e-041858141979d189c204f4c2893e3170a514ee7d5523406c
ToppCellPBMC-Mild-Lymphocyte-T/NK-NK_cell-NK_CD56bright|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

EOMES ZNF600 CD247 GOLIM4

3.60e-04185814df5d2309d19ac8d5e429afa785d0a480e75a8f9e
ToppCellpdx|World / Sample and Cell Type and Tumor Cluster (all cells)

ARID1B SPATS2L R3HDM1 PUM1

3.67e-04186814de8e538c8767d41b8a52f5e58ba1affd4e7244c4
ToppCellpdx-Tumor_cells|World / Sample and Cell Type and Tumor Cluster (all cells)

ARID1B SPATS2L R3HDM1 PUM1

3.67e-041868140b88a87158a9ca8de3bf40a4ff1687150707a5f0
ToppCellHippocampus-Macroglia-OLIGODENDROCYTE-O2-Trf-Oligodendrocyte.Trf.Ndrg2_(MyelinProcesses)|Hippocampus / BrainAtlas - Mouse McCarroll V32

NTRK1 MUC4 HSF5

3.74e-04778134720aa099bd00d05b721634eedc9a08b0213ee67
ToppCellHippocampus-Macroglia-OLIGODENDROCYTE-O2-Trf-Oligodendrocyte.Trf.Ndrg2_(MyelinProcesses)-|Hippocampus / BrainAtlas - Mouse McCarroll V32

NTRK1 MUC4 HSF5

3.74e-047781325a8dd4cdba4d96d6b0c35fa6310bfff6ce64265
ToppCellAdult-Epithelial-club_cell-D231|Adult / Lineage, Cell type, age group and donor

CDH26 CUBN PATJ MUC4

3.75e-04187814ee59d7d3de5879738ff0b9c3ea5e4847fb48cb86
ToppCell10x3'2.3-week_12-13-Mesenchymal_adipo|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

GHR PODNL1 TRPC3 ANGPTL4

3.75e-04187814f1d0fc625e0e7881b3f290742fd7148d995eb71e
ToppCell10x3'2.3-week_12-13-Mesenchymal_adipo-stroma|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

GHR PODNL1 TRPC3 ANGPTL4

3.75e-0418781402e7246ef5ad41773d14426254e139b156d45c1d
ToppCell3'_v3-lymph-node_spleen-Lymphocytic_NK-NK_CD56bright_CD16-|lymph-node_spleen / Manually curated celltypes from each tissue

EOMES CD247 DZIP3 GOLIM4

3.75e-041878149000241566f48e435db9409b7255db68b68f6059
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Degenerative_Descending_Thin_Limb_Cell_Type_3|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CFAP54 GLI3 HIPK2 PATJ

3.75e-04187814c31130fc2f9f882944b2ba366a034a03f051c4b9
ToppCell10x3'2.3-week_12-13-Mesenchymal_adipo-stroma-adipo-CAR|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

GHR PODNL1 TRPC3 ANGPTL4

3.75e-0418781408c73d125e0638c9e9878165bba2442c266c8a48
ToppCellMid-temporal_gyrus_(MTG)-Non-neuronal-Macroglial-Astro-Astrocyte-Astro_L1-6_FGFR3_ETNPPL|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

GLI3 ANGPTL4 ACSF2 TP53BP2

3.75e-0418781493c78fc7f126132eb84feb47be2c4e8c568b9e91
ToppCell10x3'2.3-week_12-13-Mesenchymal_osteo-stroma-osteochondral_precursor|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

LIFR PODNL1 ALLC KIAA1549L

3.82e-04188814ed92cddf47defea2f904d36c7ae05ffa323349a9
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

GALM ACSF2 CUBN PATJ

3.82e-04188814f3edcefeef2ce19086032d98b243c02a6d542b38
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

GALM ACSF2 CUBN PATJ

3.82e-041888140792432cd4c564dea1102241ea9884f7ced7658c
ToppCell3'_v3-bone_marrow-Lymphocytic_NK-NK_CD56bright_CD16-|bone_marrow / Manually curated celltypes from each tissue

EOMES CD247 DZIP3 GOLIM4

3.90e-041898146e402fb3fc31e4cb541e3cd140d7a86c1083dbf5
ToppCelltumor_Lung-B_lymphocytes-Undetermined|B_lymphocytes / Location, Cell class and cell subclass

EOMES CD247 GALM FCRL4

3.98e-04190814e3ba8d36e0ad9525912b1891922573b55a1d5ed9
ToppCellSomatosensory_Cortex_(S1)-Non-neuronal-Macroglial-Astro|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

GLI3 ANGPTL4 ACSF2 TP53BP2

3.98e-041908143a55cc5dc2549788bfe55f649686887b21a1fdd2
ToppCellSomatosensory_Cortex_(S1)-Non-neuronal-Macroglial-Astro-Astrocyte|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

GLI3 ANGPTL4 ACSF2 TP53BP2

3.98e-041908141c3d601422efa60fad8565f9ccd9032b847e4a91
DrugCyproterone acetate [427-51-0]; Up 200; 9.6uM; MCF7; HT_HG-U133A

PODNL1 HIPK2 NR1D1 CARD14 NLRP3 SMAD1 RAI1

6.39e-061968173545_UP
DrugFluvastatin sodium salt [93957-55-2]; Down 200; 9.2uM; MCF7; HT_HG-U133A

ZFYVE9 ZNF268 GLI3 DZIP3 MPDZ PATJ UTY

6.39e-061968175290_DN
DrugHydrastinine hydrochloride [4884-68-8]; Up 200; 16.4uM; HL60; HG-U133A

PODNL1 TDRD3 ZFYVE9 XPNPEP3 HIPK2 DAPK1 COG5

7.06e-061998171436_UP
DiseaseIdiopathic pulmonary hypertension

TBX4 SMAD1

2.45e-049782C0152171
Disease2-oxo-hept-3-ene-1,7-dioate hydratase activity

TBX4 SMAD1

6.15e-0414782C1150929
Diseasebreastfeeding duration

FBN2 ZCCHC2

6.15e-0414782EFO_0006864
Diseaseobsolete_red blood cell distribution width

FBN2 NTRK1 ANGPTL4 AK9 SIK3 ZCCHC2 R3HDM1 COG5 MUC4 NLRP3 SMAD1

8.07e-0413477811EFO_0005192
DiseaseIdiopathic pulmonary arterial hypertension

TBX4 SMAD1

8.08e-0416782C3203102
DiseaseManic Disorder

NTRK1 TRPC3 ZCCHC2

8.92e-0471783C0024713
DiseaseFamilial primary pulmonary hypertension

TBX4 SMAD1

9.14e-0417782C0340543
DiseaseManic

NTRK1 TRPC3 ZCCHC2

1.17e-0378783C0338831
DiseaseDepression, Bipolar

NTRK1 TRPC3 ZCCHC2

1.22e-0379783C0005587
Diseaseurinary microalbumin measurement

KCNN2 CUBN

1.27e-0320782EFO_0010967
Diseasechylomicron measurement, very low density lipoprotein cholesterol measurement, lipid measurement

ANGPTL4 TNKS SIK3

2.07e-0395783EFO_0004529, EFO_0008317, EFO_0008596
DiseaseMalignant neoplasm of breast

EOMES ARID1B CATSPERE UBR4 ANGPTL4 GOLIM4 SIK3 CUBN TP53BP2

2.08e-031074789C0006142
Diseasechylomicron measurement, triglyceride measurement, very low density lipoprotein cholesterol measurement

ANGPTL4 TNKS SIK3

2.13e-0396783EFO_0004530, EFO_0008317, EFO_0008596
Diseasetriglycerides:total lipids ratio, high density lipoprotein cholesterol measurement

ANGPTL4 TNKS SIK3 RAI1

2.20e-03206784EFO_0004612, EFO_0020947
Diseasepancreatic cancer (is_marker_for)

NTRK1 BAG4 MUC4

2.46e-03101783DOID:1793 (is_marker_for)

Protein segments in the cluster

PeptideGeneStartEntry
SGPHTISNQNNYRLL

ACSBG2

426

Q5FVE4
QLYGNATSDHPNNQD

BAG4

346

O95429
SFNINGLNPTAHYNV

EOMES

301

O95936
QHLLGSLSNYDVNQP

DAPK1

361

P53355
HYRLSQPGLSQQQQQ

AMOT

366

Q4VCS5
SYGKVRLNNNHLPNS

CFAP54

946

Q96N23
HSNLNGQYFRSIPQQ

ANGPTL4

356

Q9BY76
LNQPYEIINSSNGNH

CATSPERE

846

Q5SY80
PASGHNYFLVNSQQR

ALLC

146

Q8N6M5
DLLIPQASSNNNGNY

FCRL4

151

Q96PJ5
GSTRQHLDQLQYNQQ

ACSF2

236

Q96CM8
LQNSHEGYPNSQCNH

ARID1B

366

Q8NFD5
AAAQNQQQHPENIYS

TP53BP2

651

Q13625
QQQHPENIYSNSQGK

TP53BP2

656

Q13625
NGDPSRYVSNHAFNQ

ISLR2

461

Q6UXK2
QNNLSSSVGYLQHPG

R3HDM1

781

Q15032
SLAPGQRVQNLHAYQ

RAI1

256

Q7Z5J4
NPTQAFTHYNINQSR

MPPED2

21

Q15777
NSNSGLQGLQFYRLH

MUC4

4536

Q99102
LRLNQPTHVNNGNYT

NTRK1

346

P04629
PTHVNNGNYTLLAAN

NTRK1

351

P04629
NSQNQAGYEQHFPSA

GLI3

1101

P10071
SNTSPYSVQQRAGHN

HIPK2

931

Q9H2X6
YSVQQRAGHNNANAF

HIPK2

936

Q9H2X6
NPSGLNQHTRNRQGQ

NGLY1

141

Q96IV0
SNENHGIAQRIYGNQ

ITIH2

466

P19823
RSNSFNNPLGNRASH

LATS1

461

O95835
PEHNNSNNLALYGTG

KCNN2

71

Q9H2S1
NSHVRYIQNSQPNLN

GABBR1

616

Q9UBS5
QQQQQSDLPGHSSYL

ATXN3L

296

Q9H3M9
DVGPNSLQRYHLNDN

PCDHGB2

161

Q9Y5G2
ISGLQQQTNYDLNGH

KIAA1549L

416

Q6ZVL6
LRNIQAGNYTAHQIN

DZIP3

116

Q86Y13
AAQQQQYALAAAHQP

PUM1

401

Q14671
QNVTQVAHSPQGYNT

GOLIM4

256

O00461
LRSVYLHNNQLSNAG

PODNL1

171

Q6PEZ8
GLQLHTNYLQNGQFS

PLA2G4E

661

Q3MJ16
SAAAHQQQLYGRSPS

KAT6A

1866

Q92794
HNEALNGLRQAPSSY

NR1D1

351

P20393
RLQQYSQHIQGNFNA

COG5

426

Q9UP83
YLQLQDSPQGHGNSR

CUBN

3336

O60494
HSYFNLAGQASPNIN

GALM

176

Q96C23
AYNQTILPNLLGHTN

FZD7

61

O75084
AHGTIPNYSRAQQQL

CARD14

731

Q9BXL6
QNNSPYHDACPATQQ

GHR

431

P10912
SRSADAPAYQQGQNQ

CD247

56

P20963
LNTLYNHQQRGRGSP

C3orf20

731

Q8ND61
GSYSGHLIANTPQQN

GCM1

216

Q9NP62
QEGNNHRPAFTQENY

CDH26

266

Q8IXH8
QPLNNHIRYVISQGN

FBN2

2826

P35556
YNFTLNAHNPLGRSQ

LIFR

406

P42702
NQNLTHLYLRGNTLG

NLRP3

911

Q96P20
YRGQHILANSNNSNP

HSF5

406

Q4G112
QRISGQRQHNNTGYI

AK9

156

Q5TCS8
ESNGNVPYLQQNTHT

UTY

551

O14607
RQATAHCPNSYVNNN

TINAGL1

321

Q9GZM7
LPSYRFNPNNHQSEQ

RNF38

446

Q9H0F5
SQPQQLHQGQYRSSN

TDRD3

291

Q9H7E2
LHQGQYRSSNTEQNG

TDRD3

296

Q9H7E2
YHNNRLNGPAKSQGS

SPATS2L

441

Q9NUQ6
NVNRFSPANYDQAHL

SIK3

876

Q9Y2K2
NQDYRNNHTLFGVLN

MSH4

326

O15457
LPGDNNNNLYGHQTF

SI

266

P14410
QFNEHYSARNLNPLS

SIX6OS1

501

Q8N1H7
YNPQHSLLAQFRNLG

SMAD1

146

Q15797
LPSICNGSYLNQAHQ

ZCCHC2

1051

Q9C0B9
PKTRISNNYGNNSLH

ZNF321P

131

Q8N8H1
SNNYGNNSLHSSLPI

ZNF321P

136

Q8N8H1
GPQDSSRQYNHAAAN

USP6NL

456

Q92738
TSDYARNNPNGFQVH

ZNF268

216

Q14587
INGQILYGRSHQNAS

MPDZ

1401

O75970
TGIQLNPNNHLQLYS

WDR75

61

Q8IWA0
NNQILYGRSHQNASA

PATJ

1291

Q8NI35
RNSTPLHLAAGYNNL

TNKS

836

O95271
QIHISNNYGNNPLNS

ZNF808

201

Q8N4W9
QALQRQPNAAQYFHQ

PHC1

41

P78364
QNPNYYNLQGISHRH

SNRNP200

1766

O75643
GNKLYDSSNRPHQNQ

ZNF418

116

Q8TF45
GGNRSNTLHYVKNNQ

XPNPEP3

306

Q9NQH7
PGNAHFSVYNQLSQS

TBX4

466

P57082
DQTNRQGQGSHYSQP

RPTN

356

Q6XPR3
NRQGQSSHYGQPDTQ

RPTN

371

Q6XPR3
QPDRQGQNSHYGQTD

RPTN

441

Q6XPR3
GQSQLYAAQHQASSP

SEC31A

921

O94979
NHPNSNIYNTLSGLV

UBR4

3506

Q5T4S7
PQIHISNNYGNNSPN

ZNF600

131

Q6ZNG1
GNYQTQAISIHNQPR

ZFYVE9

1181

O95405
HSFNSILNQPTRYQQ

TRPC3

751

Q13507
QLHGASGQQNPYTTN

TTI1

1066

O43156