Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	extracellular matrix structural constituent conferring tensile strength	COL4A1 COL4A2 COL4A5 COL6A1 COL22A1	6.59e-06	46	115	5	GO:0030020
GeneOntologyMolecularFunction	extracellular matrix structural constituent	COL4A1 COL4A2 COL4A5 COL6A1 IMPG1 COL22A1 ELN	1.09e-04	188	115	7	GO:0005201
GeneOntologyMolecularFunction	DNA-binding transcription factor activity, RNA polymerase II-specific	UNCX GATA3 ZBTB47 IRF7 DMBX1 PGR ZNF512B ZNF771 OTP FOXD4L1 PROX2 GLIS2 SP6 TPRX1 DMRTA2 ZFHX3 GLIS1 ZNF367 SP140 TBX6	1.53e-04	1412	115	20	GO:0000981
GeneOntologyMolecularFunction	group III metabotropic glutamate receptor activity	GRM4 GRM7	1.96e-04	4	115	2	GO:0001642
GeneOntologyCellularComponent	collagen type IV trimer	COL4A1 COL4A2 COL4A5	3.46e-06	6	118	3	GO:0005587
GeneOntologyCellularComponent	basement membrane collagen trimer	COL4A1 COL4A2 COL4A5	9.62e-06	8	118	3	GO:0098651
GeneOntologyCellularComponent	network-forming collagen trimer	COL4A1 COL4A2 COL4A5	9.62e-06	8	118	3	GO:0098642
GeneOntologyCellularComponent	collagen network	COL4A1 COL4A2 COL4A5	9.62e-06	8	118	3	GO:0098645
GeneOntologyCellularComponent	collagen trimer	COL4A1 COL4A2 COL4A5 COL6A1 COL22A1 C1QA	1.06e-05	88	118	6	GO:0005581
GeneOntologyCellularComponent	complex of collagen trimers	COL4A1 COL4A2 COL4A5	2.17e-04	21	118	3	GO:0098644
GeneOntologyCellularComponent	chromatin	UNCX GATA3 IRF7 MSL1 ICE1 XPC DMBX1 MBD3 PHC1 PGR OTP FOXD4L1 PROX2 SP6 TPRX1 DMRTA2 ZFHX3 TNKS1BP1 TAF6 TBX6	2.23e-04	1480	118	20	GO:0000785
GeneOntologyCellularComponent	basement membrane	COL4A1 COL4A2 COL4A5 COL6A1 LAMB4	6.45e-04	122	118	5	GO:0005604
GeneOntologyCellularComponent	collagen-containing extracellular matrix	COL4A1 COL4A2 COL4A5 COL6A1 LAMB4 IMPG1 BCAN COL22A1 C1QA ELN	8.51e-04	530	118	10	GO:0062023
GeneOntologyCellularComponent	extracellular matrix	COL4A1 COL4A2 COL4A5 COL6A1 LAMB4 ZAN IMPG1 BCAN COL22A1 C1QA ELN	1.23e-03	656	118	11	GO:0031012
GeneOntologyCellularComponent	external encapsulating structure	COL4A1 COL4A2 COL4A5 COL6A1 LAMB4 ZAN IMPG1 BCAN COL22A1 C1QA ELN	1.26e-03	658	118	11	GO:0030312
Domain	C4	COL4A1 COL4A2 COL4A5	4.49e-06	6	115	3	SM00111
Domain	Collagen_VI_NC	COL4A1 COL4A2 COL4A5	4.49e-06	6	115	3	IPR001442
Domain	NC1_IV	COL4A1 COL4A2 COL4A5	4.49e-06	6	115	3	PS51403
Domain	-	COL4A1 COL4A2 COL4A5	4.49e-06	6	115	3	2.170.240.10
Domain	C4	COL4A1 COL4A2 COL4A5	4.49e-06	6	115	3	PF01413
Domain	Collagen	COL4A1 COL4A2 COL4A5 COL6A1 COL22A1 C1QA	1.41e-05	85	115	6	IPR008160
Domain	Collagen	COL4A1 COL4A2 COL4A5 COL6A1 COL22A1 C1QA	1.41e-05	85	115	6	PF01391
Domain	GPCR_3	GRM4 GRM7 GPR179	2.79e-04	21	115	3	IPR000337
Domain	7tm_3	GRM4 GRM7 GPR179	3.22e-04	22	115	3	PF00003
Domain	G_PROTEIN_RECEP_F3_2	GRM4 GRM7 GPR179	3.22e-04	22	115	3	PS00980
Domain	G_PROTEIN_RECEP_F3_3	GRM4 GRM7 GPR179	3.22e-04	22	115	3	PS00981
Domain	G_PROTEIN_RECEP_F3_1	GRM4 GRM7 GPR179	3.22e-04	22	115	3	PS00979
Domain	G_PROTEIN_RECEP_F3_4	GRM4 GRM7 GPR179	3.22e-04	22	115	3	PS50259
Domain	GPCR_3_C	GRM4 GRM7 GPR179	3.22e-04	22	115	3	IPR017978
Domain	EGF	ZAN BCAN CUBN GPR179 NRXN2 NAGPA MEGF10	6.33e-04	235	115	7	SM00181
Domain	EGF-like_dom	ZAN IMPG1 BCAN CUBN NRXN2 NAGPA MEGF10	8.89e-04	249	115	7	IPR000742
Domain	EGF_1	LAMB4 ZAN BCAN CUBN NRXN2 NAGPA MEGF10	1.02e-03	255	115	7	PS00022
Domain	GPCR_3_mtglu_rcpt	GRM4 GRM7	1.03e-03	8	115	2	IPR000162
Domain	EGF	ZAN BCAN CUBN NRXN2 NAGPA	1.10e-03	126	115	5	PF00008
Domain	EGF-like_CS	LAMB4 ZAN BCAN CUBN NRXN2 NAGPA MEGF10	1.17e-03	261	115	7	IPR013032
Domain	EGF_2	LAMB4 ZAN BCAN CUBN NRXN2 NAGPA MEGF10	1.27e-03	265	115	7	PS01186
Pathway	REACTOME_COLLAGEN_CHAIN_TRIMERIZATION	COL4A1 COL4A2 COL4A5 COL6A1 COL22A1	5.93e-06	41	90	5	MM15538
Pathway	REACTOME_NCAM1_INTERACTIONS	COL4A1 COL4A2 COL4A5 COL6A1	6.96e-06	20	90	4	MM15061
Pathway	REACTOME_COLLAGEN_CHAIN_TRIMERIZATION	COL4A1 COL4A2 COL4A5 COL6A1 COL22A1	8.46e-06	44	90	5	M27812
Pathway	BIOCARTA_NPP1_PATHWAY	COL4A1 COL4A2 COL4A5	2.92e-05	10	90	3	M22040
Pathway	BIOCARTA_NPP1_PATHWAY	COL4A1 COL4A2 COL4A5	2.92e-05	10	90	3	MM1560
Pathway	BIOCARTA_VITCB_PATHWAY	COL4A1 COL4A2 COL4A5	4.00e-05	11	90	3	M15422
Pathway	REACTOME_COLLAGEN_BIOSYNTHESIS_AND_MODIFYING_ENZYMES	COL4A1 COL4A2 COL4A5 COL6A1 COL22A1	4.26e-05	61	90	5	MM14637
Pathway	BIOCARTA_VITCB_PATHWAY	COL4A1 COL4A2 COL4A5	5.31e-05	12	90	3	MM1526
Pathway	REACTOME_COLLAGEN_BIOSYNTHESIS_AND_MODIFYING_ENZYMES	COL4A1 COL4A2 COL4A5 COL6A1 COL22A1	6.70e-05	67	90	5	M26999
Pathway	BIOCARTA_ACE2_PATHWAY	COL4A1 COL4A2 COL4A5	6.87e-05	13	90	3	MM1347
Pathway	BIOCARTA_ACE2_PATHWAY	COL4A1 COL4A2 COL4A5	6.87e-05	13	90	3	M12950
Pathway	BIOCARTA_PLATELETAPP_PATHWAY	COL4A1 COL4A2 COL4A5	8.71e-05	14	90	3	MM1458
Pathway	BIOCARTA_PLATELETAPP_PATHWAY	COL4A1 COL4A2 COL4A5	8.71e-05	14	90	3	M6487
Pathway	REACTOME_DEGRADATION_OF_THE_EXTRACELLULAR_MATRIX	COL4A1 COL4A2 COL4A5 COL6A1 BCAN ELN	8.78e-05	114	90	6	MM14571
Pathway	REACTOME_NCAM_SIGNALING_FOR_NEURITE_OUT_GROWTH	COL4A1 COL4A2 COL4A5 COL6A1	9.71e-05	38	90	4	MM14969
Pathway	REACTOME_ANCHORING_FIBRIL_FORMATION	COL4A1 COL4A2 COL4A5	1.08e-04	15	90	3	M27161
Pathway	REACTOME_LAMININ_INTERACTIONS	COL4A1 COL4A2 COL4A5	1.08e-04	15	90	3	MM14922
Pathway	REACTOME_ECM_PROTEOGLYCANS	COL4A1 COL4A2 COL4A5 COL6A1 BCAN	1.23e-04	76	90	5	M27219
Pathway	REACTOME_COLLAGEN_FORMATION	COL4A1 COL4A2 COL4A5 COL6A1 COL22A1	1.23e-04	76	90	5	MM14573
Pathway	REACTOME_NCAM1_INTERACTIONS	COL4A1 COL4A2 COL4A5 COL6A1	1.44e-04	42	90	4	M7169
Pathway	REACTOME_CROSSLINKING_OF_COLLAGEN_FIBRILS	COL4A1 COL4A2 COL4A5	1.92e-04	18	90	3	M27164
Pathway	REACTOME_CROSSLINKING_OF_COLLAGEN_FIBRILS	COL4A1 COL4A2 COL4A5	1.92e-04	18	90	3	MM14882
Pathway	BIOCARTA_AMI_PATHWAY	COL4A1 COL4A2 COL4A5	2.65e-04	20	90	3	M15394
Pathway	REACTOME_DEGRADATION_OF_THE_EXTRACELLULAR_MATRIX	COL4A1 COL4A2 COL4A5 COL6A1 BCAN ELN	2.71e-04	140	90	6	M587
Pathway	REACTOME_COLLAGEN_FORMATION	COL4A1 COL4A2 COL4A5 COL6A1 COL22A1	2.72e-04	90	90	5	M631
Pathway	REACTOME_ASSEMBLY_OF_COLLAGEN_FIBRILS_AND_OTHER_MULTIMERIC_STRUCTURES	COL4A1 COL4A2 COL4A5 COL6A1	2.86e-04	50	90	4	MM14796
Pathway	REACTOME_COLLAGEN_DEGRADATION	COL4A1 COL4A2 COL4A5 COL6A1	3.58e-04	53	90	4	MM14566
Pathway	BIOCARTA_INTRINSIC_PATHWAY	COL4A1 COL4A2 COL4A5	4.06e-04	23	90	3	M15997
Pathway	BIOCARTA_INTRINSIC_PATHWAY	COL4A1 COL4A2 COL4A5	4.06e-04	23	90	3	MM1427
Pathway	REACTOME_SIGNALING_BY_PDGF	COL4A1 COL4A2 COL4A5 COL6A1	4.74e-04	57	90	4	MM14713
Pathway	REACTOME_SIGNALING_BY_PDGF	COL4A1 COL4A2 COL4A5 COL6A1	5.07e-04	58	90	4	M2049
Pathway	REACTOME_ASSEMBLY_OF_COLLAGEN_FIBRILS_AND_OTHER_MULTIMERIC_STRUCTURES	COL4A1 COL4A2 COL4A5 COL6A1	6.14e-04	61	90	4	M27103
Pathway	REACTOME_NCAM_SIGNALING_FOR_NEURITE_OUT_GROWTH	COL4A1 COL4A2 COL4A5 COL6A1	6.94e-04	63	90	4	M11187
Pathway	REACTOME_COLLAGEN_DEGRADATION	COL4A1 COL4A2 COL4A5 COL6A1	7.37e-04	64	90	4	M26953
Pathway	REACTOME_LAMININ_INTERACTIONS	COL4A1 COL4A2 COL4A5	9.02e-04	30	90	3	M27216
Pathway	REACTOME_NON_INTEGRIN_MEMBRANE_ECM_INTERACTIONS	COL4A1 COL4A2 COL4A5	1.09e-03	32	90	3	MM14924
Pathway	PID_AVB3_INTEGRIN_PATHWAY	COL4A1 COL4A5 COL6A1 ADGRA2	1.27e-03	74	90	4	M160
Pathway	REACTOME_EXTRACELLULAR_MATRIX_ORGANIZATION	COL4A1 COL4A2 COL4A5 COL6A1 BCAN COL22A1 ELN	1.30e-03	258	90	7	MM14572
Pathway	REACTOME_INTEGRIN_CELL_SURFACE_INTERACTIONS	COL4A1 COL4A2 COL4A5 COL6A1	1.40e-03	76	90	4	MM14867
Pubmed	A census of human transcription factors: function, expression and evolution.	UNCX GATA3 ID4 IRF7 DMBX1 PGR OTP FOXD4L1 ZFP36L2 PROX2 SP6 TPRX1 DMRTA2 ZFHX3 GLIS1 TBX6	1.27e-07	908	122	16	19274049
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	COL4A5 C15orf39 ICE1 BCL9 FHIP1B ADGRA2 MBD3 CABLES1 PPP1R26 CCDC88C IER5L ZFP36L2 OSBPL5 TNKS1BP1 IRS2 DOT1L ANKRD16	3.39e-07	1105	122	17	35748872
Pubmed	Extracellular matrix of the human optic nerve head.	COL4A1 COL4A2 COL4A5	8.36e-07	6	122	3	2426947
Pubmed	Lysyl oxidase is essential for normal development and function of the respiratory system and for the integrity of elastic and collagen fibers in various tissues.	COL4A1 COL4A2 ELN	8.36e-07	6	122	3	16192629
Pubmed	Insertional mutation of the collagen genes Col4a3 and Col4a4 in a mouse model of Alport syndrome.	COL4A1 COL4A2 COL4A5	8.36e-07	6	122	3	10534397
Pubmed	Developmental distribution of collagen IV isoforms and relevance to ocular diseases.	COL4A1 COL4A2 COL4A5	8.36e-07	6	122	3	19275937
Pubmed	Distribution of basement membrane proteins in normal and fibrotic human liver: collagen type IV, laminin, and fibronectin.	COL4A1 COL4A2 COL4A5	8.36e-07	6	122	3	6988303
Pubmed	Stimulation of extracellular matrix components in the normal brain by invading glioma cells.	COL4A1 COL4A2 COL4A5	8.36e-07	6	122	3	9506531
Pubmed	HIV-1 gp160 protein-macrophage interactions modulate mesangial cell proliferation and matrix synthesis.	COL4A1 COL4A2 COL4A5	8.36e-07	6	122	3	7495302
Pubmed	Angiogenesis and collagen type IV expression in different endothelial cell culture systems.	COL4A1 COL4A2 COL4A5	8.36e-07	6	122	3	23551189
Pubmed	Monoclonal antibody to human basement membrane collagen type IV.	COL4A1 COL4A2 COL4A5	8.36e-07	6	122	3	6811420
Pubmed	Immunolocalization of collagen types, laminin and fibronectin in the normal human pancreas.	COL4A1 COL4A2 COL4A5	8.36e-07	6	122	3	6389236
Pubmed	Collagen IV in the developing lens capsule.	COL4A1 COL4A2 COL4A5	8.36e-07	6	122	3	12225806
Pubmed	A tumor derived motility factor that stimulates cell migration on extracellular matrix.	COL4A1 COL4A2 COL4A5	8.36e-07	6	122	3	9673377
Pubmed	Localization of type IV collagen a 1 to a 6 chains in basement membrane during mouse molar germ development.	COL4A1 COL4A2 COL4A5	8.36e-07	6	122	3	11732842
Pubmed	Regulation of protease nexin-1 target protease specificity by collagen type IV.	COL4A1 COL4A2 COL4A5	1.46e-06	7	122	3	8006028
Pubmed	Corneal cell proteins and ocular surface pathology.	COL4A1 COL4A2 COL4A5	1.46e-06	7	122	3	10416788
Pubmed	Hypoplastic basement membrane of the lens anlage in the inheritable lens aplastic mouse (lap mouse).	COL4A1 COL4A2 COL4A5	1.46e-06	7	122	3	10716744
Pubmed	Complex patterns of expression suggest extensive roles for the alpha 2 beta 1 integrin in murine development.	COL4A1 COL4A2 COL4A5	1.46e-06	7	122	3	7521231
Pubmed	Nidogen-1. Expression and ultrastructural localization during the onset of mesoderm formation in the early mouse embryo.	COL4A1 COL4A2 COL4A5	1.46e-06	7	122	3	10639489
Pubmed	Interstitial collagens I, III, and VI sequester and modulate the multifunctional cytokine oncostatin M.	COL4A1 COL4A2 COL4A5	1.46e-06	7	122	3	11711546
Pubmed	Purification, partial characterization of rat kidney hyaluronic acid binding protein and its localization on the cell surface.	COL4A1 COL4A2 COL4A5	1.46e-06	7	122	3	1724753
Pubmed	Type VI collagen anchors endothelial basement membranes by interacting with type IV collagen.	COL4A1 COL4A2 COL6A1	1.46e-06	7	122	3	9334230
Pubmed	Short amino acid sequences derived from C1q receptor (C1q-R) show homology with the alpha chains of fibronectin and vitronectin receptors and collagen type IV.	COL4A1 COL4A2 COL4A5	2.33e-06	8	122	3	1377218
Pubmed	Discoidin domain receptor 1 functions in axon extension of cerebellar granule neurons.	COL4A1 COL4A2 COL4A5	2.33e-06	8	122	3	10970885
Pubmed	Appearance and persistence of fibronectin in cartilage. Specific interaction of fibronectin with collagen type II.	COL4A1 COL4A2 COL4A5	2.33e-06	8	122	3	3997552
Pubmed	Type IV collagen α6 chain is a regulator of keratin 10 in keratinization of oral mucosal epithelium.	COL4A1 COL4A2 COL4A5	2.33e-06	8	122	3	29422532
Pubmed	Transforming growth factor-beta and p-21: multiple molecular targets of decorin-mediated suppression of neoplastic growth.	COL4A1 COL4A2 COL4A5	2.33e-06	8	122	3	10382266
Pubmed	Developmental changes in seminiferous tubule extracellular matrix components of the mouse testis: alpha 3(IV) collagen chain expressed at the initiation of spermatogenesis.	COL4A1 COL4A2 COL4A5	3.48e-06	9	122	3	8562707
Pubmed	Krüppel-like zinc-finger transcription factor KLF5/BTEB2 is a target for angiotensin II signaling and an essential regulator of cardiovascular remodeling.	COL4A1 COL4A2 COL4A5	3.48e-06	9	122	3	12101409
Pubmed	MMP-9 from TNF alpha-stimulated keratinocytes binds to cell membranes and type I collagen: a cause for extended matrix degradation in inflammation?	COL4A1 COL4A2 COL4A5	3.48e-06	9	122	3	9878537
Pubmed	Distribution of fibronectin, type I collagen, type IV collagen, and laminin in the cardiac jelly of the mouse embryonic heart with retinoic acid-induced complete transposition of the great arteries.	COL4A1 COL4A2 COL4A5	4.96e-06	10	122	3	9415455
Pubmed	Interaction between Alzheimer's disease beta A4 precursor protein (APP) and the extracellular matrix: evidence for the participation of heparan sulfate proteoglycans.	COL4A1 COL4A2 COL4A5	4.96e-06	10	122	3	9136074
Pubmed	Binding of mouse and human fibulin-2 to extracellular matrix ligands.	COL4A1 COL4A2 COL4A5	6.81e-06	11	122	3	7500359
Pubmed	Involvement of SIP1 in positioning of somite boundaries in the mouse embryo.	UNCX AXIN2 TBX6	6.81e-06	11	122	3	16127714
Pubmed	Collagen IV is essential for basement membrane stability but dispensable for initiation of its assembly during early development.	COL4A1 COL4A2 COL4A5	6.81e-06	11	122	3	14998921
Pubmed	Dynamic expression of Lrp2 pathway members reveals progressive epithelial differentiation of primitive endoderm in mouse blastocyst.	COL4A1 COL4A2 CUBN	6.81e-06	11	122	3	18083160
Pubmed	Sensory ataxia and muscle spindle agenesis in mice lacking the transcription factor Egr3.	COL4A1 COL4A2 COL4A5	6.81e-06	11	122	3	9731539
Pubmed	A genome-wide screen to identify transcription factors expressed in pelvic Ganglia of the lower urinary tract.	RNF31 GATA3 ID4 DMBX1 PHC1 PGR OTP FOXD4L1 PROX2 SP6 ZFHX3 DCUN1D3	7.90e-06	709	122	12	22988430
Pubmed	Characterization of the Extracellular Matrix of Normal and Diseased Tissues Using Proteomics.	COL4A1 COL4A2 COL4A5 COL6A1 C1QA ELN	8.55e-06	135	122	6	28675934
Pubmed	Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.	INTU RNF31 GCDH XPC CUL7 MBD3 ZNF512B TUBGCP6 ZNF771 ZNF469 ZFHX3 IRS2 TAF6 SP140 RPAP2	8.96e-06	1116	122	15	31753913
Pubmed	Muscle progenitor cells failing to respond to positional cues adopt non-myogenic fates in myf-5 null mice.	COL4A1 COL4A2 COL4A5	9.05e-06	12	122	3	8918877
Pubmed	Basement membrane fragility underlies embryonic lethality in fukutin-null mice.	COL4A1 COL4A2 COL4A5	9.05e-06	12	122	3	15837576
Pubmed	Compound genetic ablation of nidogen 1 and 2 causes basement membrane defects and perinatal lethality in mice.	COL4A1 COL4A2 COL4A5	9.05e-06	12	122	3	16024816
Pubmed	Matrilin-2 interacts with itself and with other extracellular matrix proteins.	COL4A1 COL4A2 COL4A5	9.05e-06	12	122	3	12180907
Pubmed	A stem cell roadmap of ribosome heterogeneity reveals a function for RPL10A in mesoderm production.	UNCX AXIN2 TBX6	9.05e-06	12	122	3	36123354
Pubmed	Basal lamina molecules are concentrated in myogenic regions of the mouse limb bud.	COL4A1 COL4A2 COL4A5	1.17e-05	13	122	3	9833687
Pubmed	Prevalence of COL4A1 and COL4A2 mutations in severe fetal multifocal hemorrhagic and/or ischemic cerebral lesions.	COL4A1 COL4A2	1.22e-05	2	122	2	32515830
Pubmed	Sequence variants in COL4A1 and COL4A2 genes in Ecuadorian families with keratoconus.	COL4A1 COL4A2	1.22e-05	2	122	2	21527998
Pubmed	Is there relation between COL4A1/A2 mutations and antenatally detected fetal intraventricular hemorrhage?	COL4A1 COL4A2	1.22e-05	2	122	2	24317722
Pubmed	Head-to-head arrangement of murine type IV collagen genes.	COL4A1 COL4A2	1.22e-05	2	122	2	3198626
Pubmed	Intracerebral hemorrhage in a neonate with an intragenic COL4A2 duplication.	COL4A1 COL4A2	1.22e-05	2	122	2	33247988
Pubmed	Identification of a common epitope in the sequences of COL4A1 and COL6A1 recognized by monoclonal antibody #141.	COL4A1 COL6A1	1.22e-05	2	122	2	30321347
Pubmed	Replication of Top Loci From COL4A1/2 Associated With White Matter Hyperintensity Burden in Patients With Ischemic Stroke.	COL4A1 COL4A2	1.22e-05	2	122	2	33148145
Pubmed	The genes for the alpha 1(IV) and alpha 2(IV) chains of human basement membrane collagen type IV are arranged head-to-head and separated by a bidirectional promoter of unique structure.	COL4A1 COL4A2	1.22e-05	2	122	2	2846280
Pubmed	Genotype-phenotype correlations in pathology caused by collagen type IV alpha 1 and 2 mutations.	COL4A1 COL4A2	1.22e-05	2	122	2	27794444
Pubmed	Next-generation sequencing in a large pedigree segregating visceral artery aneurysms suggests potential role of COL4A1/COL4A2 in disease etiology.	COL4A1 COL4A2	1.22e-05	2	122	2	34281442
Pubmed	COL4A1 and COL4A2 mutations and disease: insights into pathogenic mechanisms and potential therapeutic targets.	COL4A1 COL4A2	1.22e-05	2	122	2	22914737
Pubmed	CUL7 E3 Ubiquitin Ligase Mediates the Degradation of Activation-Induced Cytidine Deaminase and Regulates the Ig Class Switch Recombination in B Lymphocytes.	CUL7 CD19	1.22e-05	2	122	2	31092637
Pubmed	[Collagen alpha5 and alpha2 (IV) chain coexpression: The procedure of choice to diagnose Alport syndrome from skin biopsies].	COL4A2 COL4A5	1.22e-05	2	122	2	18706356
Pubmed	Crystal structure of NC1 domains. Structural basis for type IV collagen assembly in basement membranes.	COL4A1 COL4A2	1.22e-05	2	122	2	11970952
Pubmed	Characterization of Glis2, a novel gene encoding a Gli-related, Krüppel-like transcription factor with transactivation and repressor functions. Roles in kidney development and neurogenesis.	GLIS2 GLIS1	1.22e-05	2	122	2	11741991
Pubmed	A novel sequence in the type IV collagen promoter binds nuclear proteins from Engelbreth-Holm-Swarm tumor.	COL4A1 COL4A2	1.22e-05	2	122	2	1630813
Pubmed	The structural genes for alpha 1 and alpha 2 chains of human type IV collagen are divergently encoded on opposite DNA strands and have an overlapping promoter region.	COL4A1 COL4A2	1.22e-05	2	122	2	3182844
Pubmed	The arrangement of intra- and intermolecular disulfide bonds in the carboxyterminal, non-collagenous aggregation and cross-linking domain of basement-membrane type IV collagen.	COL4A1 COL4A2	1.22e-05	2	122	2	2844531
Pubmed	Identification of a novel sequence element in the common promoter region of human collagen type IV genes, involved in the regulation of divergent transcription.	COL4A1 COL4A2	1.22e-05	2	122	2	8317999
Pubmed	Type IV procollagen missense mutations associated with defects of the eye, vascular stability, the brain, kidney function and embryonic or postnatal viability in the mouse, Mus musculus: an extension of the Col4a1 allelic series and the identification of the first two Col4a2 mutant alleles.	COL4A1 COL4A2	1.22e-05	2	122	2	17179069
Pubmed	Collagen IV deficiency causes hypertrophic remodeling and endothelium-dependent hyperpolarization in small vessel disease with intracerebral hemorrhage.	COL4A1 COL4A2	1.22e-05	2	122	2	39216230
Pubmed	Distinct expression patterns of alpha1 (IV) and alpha5 (IV) collagen chains in cylindroma and malignant cylindroma.	COL4A1 COL4A5	1.22e-05	2	122	2	15583824
Pubmed	The Col4a2em1(IMPC)Wtsi mouse line: lessons from the Deciphering the Mechanisms of Developmental Disorders program.	COL4A1 COL4A2	1.22e-05	2	122	2	31331924
Pubmed	4-Sodium phenyl butyric acid has both efficacy and counter-indicative effects in the treatment of Col4a1 disease.	COL4A1 COL4A2	1.22e-05	2	122	2	30351356
Pubmed	Mutations in Col4a1 cause perinatal cerebral hemorrhage and porencephaly.	COL4A1 COL4A2	1.22e-05	2	122	2	15905400
Pubmed	Allelic heterogeneity contributes to variability in ocular dysgenesis, myopathy and brain malformations caused by Col4a1 and Col4a2 mutations.	COL4A1 COL4A2	1.22e-05	2	122	2	24203695
Pubmed	Association study of polymorphisms in the group III metabotropic glutamate receptor genes, GRM4 and GRM7, with schizophrenia.	GRM4 GRM7	1.22e-05	2	122	2	19351574
Pubmed	Material-driven fibronectin assembly rescues matrix defects due to mutations in collagen IV in fibroblasts.	COL4A1 COL4A2	1.22e-05	2	122	2	32413593
Pubmed	NMR studies demonstrate a unique AAB composition and chain register for a heterotrimeric type IV collagen model peptide containing a natural interruption site.	COL4A1 COL4A2	1.22e-05	2	122	2	26209635
Pubmed	Glomerular expression of alpha2(IV) and alpha5(IV) chains of type IV collagen in patients with IgA nephropathy.	COL4A2 COL4A5	1.22e-05	2	122	2	12021518
Pubmed	Do mutations in COL4A1 or COL4A2 cause thin basement membrane nephropathy (TBMN)?	COL4A1 COL4A2	1.22e-05	2	122	2	17216253
Pubmed	Epilepsy and related challenges in children with COL4A1 and COL4A2 mutations: A Gould syndrome patient registry.	COL4A1 COL4A2	1.22e-05	2	122	2	34735964
Pubmed	Neurologic phenotypes associated with COL4A1/2 mutations: Expanding the spectrum of disease.	COL4A1 COL4A2	1.22e-05	2	122	2	30413629
Pubmed	Collagen alpha5 and alpha2(IV) chain coexpression: analysis of skin biopsies of Alport patients.	COL4A2 COL4A5	1.22e-05	2	122	2	17554254
Pubmed	Anti-angiogenic collagen fragment arresten is increased from 16 weeks' gestation in pre-eclamptic plasma.	COL4A1 COL4A2	1.22e-05	2	122	2	26343951
Pubmed	Col4a1 mutations cause progressive retinal neovascular defects and retinopathy.	COL4A1 COL4A2	1.22e-05	2	122	2	26813606
Pubmed	Extensive homology between the carboxyl-terminal peptides of mouse alpha 1(IV) and alpha 2(IV) collagen.	COL4A1 COL4A2	1.22e-05	2	122	2	3597383
Pubmed	Alpha 1(IV) and alpha 2(IV) collagen genes are regulated by a bidirectional promoter and a shared enhancer.	COL4A1 COL4A2	1.22e-05	2	122	2	3200851
Pubmed	COL4A2 mutations impair COL4A1 and COL4A2 secretion and cause hemorrhagic stroke.	COL4A1 COL4A2	1.22e-05	2	122	2	22209247
Pubmed	Role of α1 and α2 chains of type IV collagen in early fibrotic lesions of idiopathic interstitial pneumonias and migration of lung fibroblasts.	COL4A1 COL4A2	1.22e-05	2	122	2	26006016
Pubmed	Further refinement of COL4A1 and COL4A2 related cortical malformations.	COL4A1 COL4A2	1.22e-05	2	122	2	30315939
Pubmed	Prenatal clinical manifestations in individuals with COL4A1/2 variants.	COL4A1 COL4A2	1.22e-05	2	122	2	32732225
Pubmed	The 1.9-A crystal structure of the noncollagenous (NC1) domain of human placenta collagen IV shows stabilization via a novel type of covalent Met-Lys cross-link.	COL4A1 COL4A2	1.22e-05	2	122	2	12011424
Pubmed	Post-translational modification of type IV collagen with 3-hydroxyproline affects its interactions with glycoprotein VI and nidogens 1 and 2.	COL4A1 COL4A2	1.22e-05	2	122	2	29491144
Pubmed	Abnormal expression of collagen IV in lens activates unfolded protein response resulting in cataract.	COL4A1 COL4A2 COL4A5	1.49e-05	14	122	3	19858219
Pubmed	Characterization of the enzymatic activity of human kallikrein 6: Autoactivation, substrate specificity, and regulation by inhibitors.	COL4A1 COL4A2 COL4A5	1.49e-05	14	122	3	12878203
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	TRIOBP ICE1 ADGRA2 RCC2 LRRC47 ZNF512B TUBGCP6 NRXN2 OSBPL5 TNKS1BP1	1.83e-05	529	122	10	14621295
Pubmed	Dynamic CREB family activity drives segmentation and posterior polarity specification in mammalian somitogenesis.	UNCX AXIN2 TBX6	1.86e-05	15	122	3	23671110
Pubmed	Defective glomerulogenesis in the absence of laminin alpha5 demonstrates a developmental role for the kidney glomerular basement membrane.	COL4A1 COL4A2 COL4A5	1.86e-05	15	122	3	10625553
Pubmed	Localization of basement membrane-associated protein isoforms during development of the ocular surface of mouse eye.	COL4A1 COL4A2 COL4A5	1.86e-05	15	122	3	9264260
Pubmed	Inhibition of distal lung morphogenesis in Nkx2.1(-/-) embryos.	COL4A1 COL4A2 COL4A5	1.86e-05	15	122	3	10706142
Pubmed	A locus for renal malformations including vesico-ureteric reflux on chromosome 13q33-34.	COL4A1 COL4A2 IRS2	1.86e-05	15	122	3	16565260
Pubmed	Identification of a novel cell-adhesive protein spatiotemporally expressed in the basement membrane of mouse developing hair follicle.	COL4A1 COL4A2 COL4A5	2.28e-05	16	122	3	15878328
Interaction	DCN interactions	COL4A1 COL4A5 COL6A1 C1QA ELN	4.12e-06	43	113	5	int:DCN
Interaction	BGN interactions	COL4A1 COL4A2 COL6A1 ELN	2.29e-05	30	113	4	int:BGN
Interaction	FBLN2 interactions	COL4A1 COL4A2 COL4A5 BCAN ELN	3.45e-05	66	113	5	int:FBLN2
Interaction	COLGALT2 interactions	COL4A1 COL4A2 COL4A5 COL6A1 C1QA	3.71e-05	67	113	5	int:COLGALT2
Cytoband	13q34	COL4A1 COL4A2 IRS2	4.11e-04	54	122	3	13q34
Cytoband	19p13.3	AMH APC2 HCN2 MBD3 DOT1L	4.46e-04	237	122	5	19p13.3
GeneFamily	Collagens	COL4A1 COL4A2 COL4A5 COL6A1 COL22A1	2.13e-06	46	83	5	490
GeneFamily	Glutamate metabotropic receptors\|Protein phosphatase 1 regulatory subunits	GRM4 GRM7	5.73e-04	8	83	2	281
GeneFamily	PRD class homeoboxes and pseudogenes	UNCX DMBX1 OTP TPRX1	8.49e-04	92	83	4	521
Coexpression	DESCARTES_ORGANOGENESIS_PREMATURE_OLIGODENDROCYTE	NWD1 ID4 ANKMY1 BCAN DMRTA2	1.12e-06	40	121	5	MM3636
Coexpression	NABA_BASEMENT_MEMBRANES	COL4A1 COL4A2 COL4A5 COL6A1 LAMB4	1.12e-06	40	121	5	M5887
Coexpression	NABA_COLLAGENS	COL4A1 COL4A2 COL4A5 COL6A1 COL22A1	1.61e-06	43	121	5	MM17060
Coexpression	NABA_COLLAGENS	COL4A1 COL4A2 COL4A5 COL6A1 COL22A1	1.81e-06	44	121	5	M3005
Coexpression	HEBERT_MATRISOME_TNBC_LUNG_METASTASIS	COL4A1 COL4A2 COL4A5 ELN	3.57e-06	23	121	4	M48001
Coexpression	NABA_CORE_MATRISOME	COL4A1 COL4A2 COL4A5 COL6A1 LAMB4 IMPG1 BCAN COL22A1 ELN	5.48e-06	275	121	9	M5884
Coexpression	DOUGLAS_BMI1_TARGETS_UP	COL4A1 COL4A2 COL6A1 C15orf39 BCL9 ADGRA2 MAP3K12 CABLES1 DCHS1 IRS2 ELN ZNF367	1.20e-05	563	121	12	M15103
Coexpression	NABA_CORE_MATRISOME	COL4A1 COL4A2 COL4A5 COL6A1 IMPG1 BCAN COL22A1 ELN	3.77e-05	270	121	8	MM17057
Coexpression	KANG_AR_TARGETS_UP	COL4A1 COL4A2 COL6A1	6.22e-05	17	121	3	MM1297
Coexpression	KANG_AR_TARGETS_UP	COL4A1 COL4A2 COL6A1	6.22e-05	17	121	3	M2223
Coexpression	LIM_MAMMARY_LUMINAL_MATURE_DN	COL4A1 COL4A2 COL6A1 AXIN2 IRS2	7.63e-05	94	121	5	M2580
Coexpression	LIM_MAMMARY_LUMINAL_MATURE_DN	COL4A1 COL4A2 COL6A1 AXIN2 IRS2	8.02e-05	95	121	5	MM1328
Coexpression	LIU_PROSTATE_CANCER_DN	COL4A1 COL4A2 COL6A1 GATA3 ZBTB47 ID4 ADGRA2 PGR TACC1 GLIS1	9.94e-05	493	121	10	M19391
Coexpression	MIKKELSEN_MEF_HCP_WITH_H3K27ME3	IL10RA UNCX AVP BCAN AMER3 DMBX1 OTP FOXD4L1 NRXN2 LYPD3 HS3ST2	1.10e-04	601	121	11	MM866
ToppCell	Brain_organoid-organoid_Paulsen_bioRxiv-1_mon-Proliferating-Cycling_Progenitors\|1_mon / Sample Type, Dataset, Time_group, and Cell type.	COL4A1 COL4A2 COL4A5 WDR36 RCC2 ZFP36L2 IRS2 MEGF10	7.96e-08	199	122	8	358c4b3037f59378db8916a2fbe9ed4830cf1449
ToppCell	critical-Lymphoid-NK\|critical / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	COL4A1 COL4A2 COL6A1 BCAN COL22A1 CABLES1 MEGF10	6.64e-07	180	122	7	5abf778395392244daaec876f306ed7e4f388686
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	COL4A1 COL4A2 CBLB ADGRA2 ZFHX3 TACC1 ELN	9.88e-07	191	122	7	04c4d454b57e29a8d1dcdeb4678ce71bdc29b77b
ToppCell	critical-Lymphoid-NK\|Lymphoid / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	COL4A1 COL4A2 COL6A1 BCAN COL22A1 CABLES1 MEGF10	1.06e-06	193	122	7	6be11fef87af04ee7a3cc223882ccd4077caded9
ToppCell	RV-02._Fibroblast_II\|RV / Chamber and Cluster_Paper	COL4A1 COL4A2 COL6A1 CBLB ZFHX3 TACC1 ELN	1.10e-06	194	122	7	11c79a8c56ece42713b04b321982e41e239f07a5
ToppCell	RV-02._Fibroblast_II\|World / Chamber and Cluster_Paper	COL4A1 COL4A2 COL6A1 CBLB ZFHX3 TACC1 ELN	1.13e-06	195	122	7	ce90b30dcdb56d4cd925cdb79fd9d7cefd998f48
ToppCell	COVID-19-lung-Pericytes/_Smooth_Muscle\|COVID-19 / Disease (COVID-19 only), tissue and cell type	COL4A1 COL4A2 COL6A1 ID4 ADGRA2 ZFHX3 TACC1	1.17e-06	196	122	7	754a3613340932563cd8424d775e18b93c3a1aaa
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen-high_Fibroblast\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	COL4A1 COL4A2 ZBTB47 CBLB PGR ELN	4.41e-06	155	122	6	82e602f31981c6b48abff2a04b2ab5d26d4462a2
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen-high_Fibroblast-\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	COL4A1 COL4A2 ZBTB47 CBLB PGR ELN	4.41e-06	155	122	6	979c1d53b435a82c57d16707eed8ba7346326866
ToppCell	facs-Brain_Non-Myeloid-Hippocampus-24m-Macroglial-astrocyte\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ZBTB47 C15orf39 CUBN GPR179 GLIS2 ANKRD16	5.49e-06	161	122	6	9f02b94e29e60d50e92eaa748ebf0c36d3671bb3
ToppCell	droplet-Limb_Muscle-MUSCLE-1m-Myeloid-chondrocyte-like\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL4A5 AVP ZBTB47 BCAN C1QA ELN	5.69e-06	162	122	6	b502d6af6868425b5c919740e011330c0d3cf3b8
ToppCell	356C-Fibroblasts-Fibroblast-C_(Myofibroblast)-\|356C / Donor, Lineage, Cell class and subclass (all cells)	COL4A1 COL4A2 COL6A1 BCAN PGR NRXN2	9.43e-06	177	122	6	cdfd2f0ee2f692271b1525e414b0f645cdadb1f6
ToppCell	356C-Fibroblasts-Fibroblast-C_(Myofibroblast)\|356C / Donor, Lineage, Cell class and subclass (all cells)	COL4A1 COL4A2 COL6A1 BCAN PGR NRXN2	9.43e-06	177	122	6	db222faaecbe5600da39277243c4e7e764eb63c9
ToppCell	Pericytes-Donor_05\|World / lung cells shred on cell class, cell subclass, sample id	COL4A1 COL4A2 COL6A1 BCAN PGR ELN	9.74e-06	178	122	6	a2448d868da2abe48c394c51264aad03e866dfec
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Degenerative_Proximal_Tubule_Epithelial_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	CUBN USH1C ADORA2A-AS1 AK4 GLIS1 PDZD2	1.01e-05	179	122	6	78fae47ec9bff4e0159a86a281e831d7f8ee925a
ToppCell	COPD-Stromal-SMC\|World / Disease state, Lineage and Cell class	COL4A1 COL4A2 COL6A1 ID4 PGR ELN	1.01e-05	179	122	6	b2709537ec1b46457ab85261f4cdd354e60a8b29
ToppCell	NS-critical-d_07-13-Lymphoid-NK\|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	COL4A1 COL4A2 COL6A1 BCAN COL22A1 CABLES1	1.11e-05	182	122	6	dd1c59babf7211362452e3e264009d70004d99f6
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_1_/_Segment_2\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	CUBN USH1C ADORA2A-AS1 AK4 GLIS1 PDZD2	1.14e-05	183	122	6	84b64cf728629c3af9a8d2ed15b93adf562c54b8
ToppCell	COVID-19-kidney-PCT-S1/S2\|kidney / Disease (COVID-19 only), tissue and cell type	CUBN USH1C ADORA2A-AS1 AK4 GLIS1 PDZD2	1.18e-05	184	122	6	dc71f22583fc54b89b242cbb602f4bbe86f576ec
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	CUBN USH1C ADORA2A-AS1 AK4 GLIS1 PDZD2	1.25e-05	186	122	6	8287146f0ba415ea04475588117d4668ae00f75c
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_3\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	CUBN USH1C ADORA2A-AS1 AK4 GLIS1 PDZD2	1.25e-05	186	122	6	a417e1e21313a7e05951038cdef5ac672a9f727c
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_1_/_Segment_2\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	CUBN USH1C ADORA2A-AS1 AK4 GLIS1 PDZD2	1.25e-05	186	122	6	5784d255e9ca449d375d81938d0fbbd8a7eb44f6
ToppCell	3'-GW_trimst-1-LargeIntestine-Mesenchymal-Pericytes-Contractile_pericyte_(PLN+)\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	COL4A1 COL4A2 ID4 ARID5A ZFHX3 ELN	1.29e-05	187	122	6	d52f7bc0afcdc366b20d199ab33c4ec60ed22a68
ToppCell	LA-01._Fibroblast_I\|World / Chamber and Cluster_Paper	COL4A2 COL6A1 CBLB LIPH ZFHX3 ELN	1.29e-05	187	122	6	4ea486991f66c29728d127171a07b81404ec0b78
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	CUBN USH1C ADORA2A-AS1 AK4 GLIS1 PDZD2	1.29e-05	187	122	6	1b82920588f9e26ef1db244d452736d75fcfd342
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	CUBN USH1C ADORA2A-AS1 AK4 GLIS1 PDZD2	1.29e-05	187	122	6	71eb26ebf60cb0848e5bf1cd01edccda621aecd8
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	CUBN USH1C ADORA2A-AS1 AK4 GLIS1 PDZD2	1.29e-05	187	122	6	dcf6475ece5b34d9d58a0d1f51c18acedb19c119
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	CUBN USH1C ADORA2A-AS1 AK4 GLIS1 PDZD2	1.29e-05	187	122	6	f1356273bd3587b6883295edf15cb9cdb706c057
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	CUBN USH1C ADORA2A-AS1 AK4 GLIS1 PDZD2	1.29e-05	187	122	6	c1e4c0345f9bfa0538730bad5ff3fa5240168b25
ToppCell	COVID-19-kidney-Stressed_PCT\|kidney / Disease (COVID-19 only), tissue and cell type	CUBN USH1C ADORA2A-AS1 AK4 GLIS1 PDZD2	1.29e-05	187	122	6	acd305475f3609800af0d7bc68d83ef41228080b
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	CUBN USH1C ADORA2A-AS1 AK4 GLIS1 PDZD2	1.33e-05	188	122	6	f3edcefeef2ce19086032d98b243c02a6d542b38
ToppCell	TCGA-Breast-Primary_Tumor-Breast_Carcinoma-Infiltrating_Lobular_Carcinoma-6\|TCGA-Breast / Sample_Type by Project: Shred V9	ZBTB47 ADGRA2 NRXN2 ZFP36L2 ELN GLIS1	1.33e-05	188	122	6	c90669b51e1902fe7726555290c91c92a911df83
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	CUBN USH1C ADORA2A-AS1 AK4 GLIS1 PDZD2	1.33e-05	188	122	6	0792432cd4c564dea1102241ea9884f7ced7658c
ToppCell	LV-01._Fibroblast_I\|World / Chamber and Cluster_Paper	COL4A1 COL4A2 COL6A1 CBLB ZFHX3 ELN	1.41e-05	190	122	6	12992ec80a7b4f4f17de693f0719ee061a9918fd
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_1\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	COL4A1 COL4A2 INTU UNCX ID4 LIPH	1.41e-05	190	122	6	a5db902ad112a0c0a0a7f1a2e38718bb3bd11412
ToppCell	3'-GW_trimst-1-SmallIntestine-Mesenchymal-Pericytes-Contractile_pericyte_(PLN+)\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	COL4A1 COL4A2 ID4 ARID5A ZFHX3 ELN	1.45e-05	191	122	6	239c1e68eb1cbe3e137a99fbd6eeb8d64c919ffd
ToppCell	facs-Lung-3m-Mesenchymal-myofibroblast\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	COL6A1 AXIN2 SP6 IRS2 MEGF10 CNTFR	1.45e-05	191	122	6	fd8331c7abdd999f55ba43d307945c6abfccbf84
ToppCell	IPF-Lymphoid-T\|World / Disease state, Lineage and Cell class	PIM2 GATA3 CBLB CCDC88C ZFP36L2 SP140	1.50e-05	192	122	6	b25ba1f3bc842c22602b2aeed3b1b5082863e4fa
ToppCell	LV-02._Fibroblast_II\|LV / Chamber and Cluster_Paper	COL4A1 COL4A2 COL6A1 ZFHX3 IRS2 ELN	1.59e-05	194	122	6	014d2feb5db2a6a35ef759761a41e466e108c3c1
ToppCell	facs-Lung-3m-Mesenchymal-myofibroblast-myofibroblast_cell\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	COL6A1 ID4 AXIN2 ELN MEGF10 CNTFR	1.63e-05	195	122	6	c6bb16c0076639c6ddef1a15d8cba44bc29c077d
ToppCell	facs-Lung-3m-Mesenchymal-myofibroblast-myofibroblast_cell-pulmonary_interstitial_myofibroblast\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	COL6A1 ID4 AXIN2 ELN MEGF10 CNTFR	1.63e-05	195	122	6	ea89f80d3d7e9f737442f7c1aa1791d277ffc90c
ToppCell	Parenchymal-NucSeq-Stromal-Myofibroblastic-Muscle_perivascular_immune_recruiting\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	COL4A1 COL4A2 COL6A1 ID4 AK4 GLIS1	1.73e-05	197	122	6	3332b9b5bf78f0203ebbd94257a36e9054d896c3
ToppCell	Bronchial-NucSeq-Stromal-Myofibroblastic-Muscle_smooth_pulmonary\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	COL4A1 COL4A2 COL6A1 ADGRA2 PGR ELN	1.73e-05	197	122	6	bf0520a94ebb1d2f94de9f526d17e0b0e8fe7052
ToppCell	5'-GW_trimst-2-LargeIntestine-Mesenchymal-Pericytes\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	COL4A1 COL4A2 ID4 ARID5A ZFHX3 ELN	1.73e-05	197	122	6	1c91e3afcc5be195b827a1dff83aff5cc2492456
ToppCell	wk_08-11-Mesenchymal-Myofibro_&_SMC\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	COL4A1 COL4A2 COL4A5 AK4 ZFHX3 ELN	1.78e-05	198	122	6	637f11e292b90d86cdc0d0d828eb26f38289c25b
ToppCell	Parenchymal-10x5prime-Stromal-Myofibroblastic\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	COL4A1 COL4A2 COL6A1 ID4 ADGRA2 ELN	1.83e-05	199	122	6	20f760d92c351a1dac4cc0a424c443ea03a179fe
ToppCell	Brain_organoid-organoid_Kanton_Nature-Organoid-2M-Radial_glial\|Organoid-2M / Sample Type, Dataset, Time_group, and Cell type.	INTU ID4 BCAN ZFP36L2 AK4 MEGF10	1.83e-05	199	122	6	75ff9a5df156c6632883eab79573f1c02c985803
ToppCell	Parenchymal-10x5prime-Stromal-Myofibroblastic-Muscle_smooth_pulmonary\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	COL4A1 COL4A2 COL6A1 ID4 ADGRA2 ELN	1.83e-05	199	122	6	7c272a1aa7f3e931ad5d20809719d85b3bce4cb0
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-10w-Macroglial-Astrocyte\|10w / Sample Type, Dataset, Time_group, and Cell type.	COL4A5 INTU ID4 BCAN ZFP36L2 MEGF10	1.89e-05	200	122	6	75f5ea38fbd341b80a8058077a04447f0e0eea28
ToppCell	Brain_organoid-organoid_Kanton_Nature-Organoid-2M-Radial_glial-RGCs_3\|Organoid-2M / Sample Type, Dataset, Time_group, and Cell type.	COL4A5 INTU ID4 ZFP36L2 DMRTA2 MEGF10	1.89e-05	200	122	6	55a1df656545ff078b727d55e4d65d61ddb5c41f
ToppCell	368C-Fibroblasts-Fibroblast-H-\|368C / Donor, Lineage, Cell class and subclass (all cells)	BCAN AXIN2 NRXN2 HS3ST2 TBX6	6.21e-05	152	122	5	dbfb4d4de36ef9f5c7da1950baa915b12788685e
ToppCell	368C-Fibroblasts-Fibroblast-H\|368C / Donor, Lineage, Cell class and subclass (all cells)	BCAN AXIN2 NRXN2 HS3ST2 TBX6	6.21e-05	152	122	5	9f3682da00fd627e80aa820ecc6f5fed23b9738a
ToppCell	368C-Lymphocytic-CD4_T-cell-CD4+_Naive_T_cell_/_CD4+_Trm_cell\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	KRT72 INTU DNAH14 AXIN2 PGR	6.21e-05	152	122	5	ca23261d8ef263cc697b8d7e7cb2afec8bc564f2
ToppCell	Substantia_nigra-Macroglia-ASTROCYTE-Gja1-Astrocyte.Gja1.Igfbp2_(Igfbp2)\|Substantia_nigra / BrainAtlas - Mouse McCarroll V32	NWD1 TTLL8 GPR179 SP6	7.64e-05	82	122	4	89aff8676f98e062d0e69b38c7184e51aa1a915e
ToppCell	Substantia_nigra-Macroglia-ASTROCYTE-Gja1-Astrocyte.Gja1.Igfbp2_(Igfbp2)--\|Substantia_nigra / BrainAtlas - Mouse McCarroll V32	NWD1 TTLL8 GPR179 SP6	7.64e-05	82	122	4	6875a10abf1221b3dfd954c319b5e8e12fac1ff2
ToppCell	Substantia_nigra-Macroglia-ASTROCYTE-Gja1-Astrocyte.Gja1.Igfbp2_(Igfbp2)-\|Substantia_nigra / BrainAtlas - Mouse McCarroll V32	NWD1 TTLL8 GPR179 SP6	7.64e-05	82	122	4	259bb4ae0373d8352cb1c3bff08f66b89a298440
ToppCell	21-Trachea-Epithelial-Submucosal_gland_basal\|Trachea / Age, Tissue, Lineage and Cell class	COL4A1 COL4A2 BCAN COL22A1 SP6	7.69e-05	159	122	5	4f670b57b8d3b090ea2f1aafe15baf93cb7ef146
ToppCell	367C-Lymphocytic-ILC-ILC-1\|367C / Donor, Lineage, Cell class and subclass (all cells)	PIM2 GATA3 CBLB ZFP36L2 TBX6	8.40e-05	162	122	5	74cd0de957fdbe527656befd61f67d6814ce9e98
ToppCell	facs-Brain_Non-Myeloid-Cerebellum_-18m-Neuronal-SPN_Neuron_STR\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL6A1 GRM4 CD163 CCDC88C FGF23	9.16e-05	165	122	5	1b7dfa173e83aa8c46a3153a3261866c065c3b73
ToppCell	facs-Brain_Non-Myeloid-Cerebellum_-18m-Neuronal-medium_spiny_neuron\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL6A1 GRM4 CD163 CCDC88C FGF23	9.16e-05	165	122	5	b4f7d33af7d053ec07b01bd67d861600a9c4822e
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Degenerative_Proximal_Tubule_Epithelial_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	NWD1 ZAN CUBN AK4 PDZD2	9.69e-05	167	122	5	3edb0570e583bb527165bcd8a4c25a042054043b
ToppCell	3'-Child04-06-SmallIntestine-Hematopoietic-T_cells-TRGV2_gdT\|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	GATA3 ZBTB47 CBLB PROX2 DCUN1D3	9.96e-05	168	122	5	2765d98f0b7f6861d662937535e051d41dba3500
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_1_/_Segment_2\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	CUBN USH1C AK4 GLIS1 PDZD2	9.96e-05	168	122	5	fa0d251693935116adf633d02b7ec4a295100865
ToppCell	TCGA-Bile_Duct-Primary_Tumor-Cholangiocarcinoma-Intrahepatic-2\|TCGA-Bile_Duct / Sample_Type by Project: Shred V9	BCAN COL22A1 SMYD2 OSBPL5 TACC1	9.96e-05	168	122	5	c70bf73bb800e4722cedc35bbc17ea3113d1012d
ToppCell	facs-Liver-Liver_non-hepato/SCs-18m-Lymphocytic-NK_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PIM2 GATA3 PPM1H OSBPL5 DMRTA2	1.02e-04	169	122	5	8028622ff362d70d1002e65a74ade46ea7f1f13f
ToppCell	RA-01._Fibroblast_I\|RA / Chamber and Cluster_Paper	COL4A2 AMH CBLB ZFHX3 ELN	1.02e-04	169	122	5	6373562ab3b1765060212a6a53d6543e7e942e80
ToppCell	10x_5'_v1-Neoplastic-Differentiated-like-MES-like-MES-like_hypoxia/MHC-Z\|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	COL6A1 IRF7 ADGRA2 TNKS1BP1 ANKRD16	1.05e-04	170	122	5	dfef8f79960979335b86b4730f224239b40735d5
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_5-Exc_L5_RORB_LINC01202\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	IL10RA GATA3 COL22A1 HS3ST2 MEGF10	1.05e-04	170	122	5	72acc9f8e4b5188ff7a7a736cbf2f87dece67e17
ToppCell	10x_5'_v1-Neoplastic-Differentiated-like-MES-like-MES-like_hypoxia/MHC\|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	COL6A1 IRF7 ADGRA2 TNKS1BP1 ANKRD16	1.05e-04	170	122	5	fb6098137d010175978596bc382e9ecba9c3891e
ToppCell	PBMC_fresh-frozen-Mild-Moderate_progression_d02_child-Lymphocytic-Lymphocytic_B-B_cell-B_c04-SOX5-TNFRSF1B\|Mild-Moderate_progression_d02_child / Compartment, severity and other cell annotations on 10x 3' data (130k)	PSMC2 TRIOBP CD163 ELN DCUN1D3	1.05e-04	170	122	5	09bcbc7eb3b1d35cf03f01ce2f2fe37373382dd4
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_1_/_Segment_2\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	CUBN ADORA2A-AS1 AK4 GLIS1 PDZD2	1.08e-04	171	122	5	f5014e3c387fe3118944af392abe10d6b9b0abab
ToppCell	390C-Myeloid-Macrophage-SPP1+_Macrophage_4\|Myeloid / Donor, Lineage, Cell class and subclass (all cells)	COL4A2 WDR36 MAP3K12 CD163 CD19	1.08e-04	171	122	5	7c8304573b892ef9ea4e048cba9ea9fbab848dcd
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_4\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	COL4A1 COL4A2 COL22A1 SMYD2 HS3ST2	1.08e-04	171	122	5	f648789e6aefe508bb748401bf9b3cd830fb0ddf
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Endothelial-Endothelial_mature-Endo_capilar-A\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	COL4A1 COL4A2 ADGRA2 PPM1H AXIN2	1.11e-04	172	122	5	c3a99828838af3b85c8c885d69cc8018f55ced50
ToppCell	Control-Stromal-Pericyte\|World / Disease state, Lineage and Cell class	COL4A1 COL4A2 COL6A1 ID4 PGR	1.11e-04	172	122	5	813d4256b05b66ca11b08cc0026459d79f12c0eb
ToppCell	facs-Heart-LV-18m-Mesenchymal-valve_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GRM7 ADGRA2 PHC1 NRXN2 TNKS1BP1	1.14e-04	173	122	5	d78397e65e997ddb995111a810f0e2a4f67d0765
ToppCell	nucseq-Mesenchymal-Fibroblastic-Fibroblastic_2-ASMC\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	COL4A1 COL4A2 COL6A1 ZFHX3 ELN	1.14e-04	173	122	5	cb6389536195443633adb06e5f1b7483530773d1
ToppCell	facs-Heart-LV-18m-Mesenchymal-valve_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GRM7 ADGRA2 PHC1 NRXN2 TNKS1BP1	1.14e-04	173	122	5	3c852ffe22f4a5b632463086b08c669310684e80
ToppCell	BAL-Mild-Myeloid-MoAM-MoAM4-\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	DMBX1 GSDME AK4 HS3ST2 EPB42	1.17e-04	174	122	5	fe105550a43b935affc73e32796115d20328a2f8
ToppCell	Control-Stromal-Pericyte\|Control / Disease state, Lineage and Cell class	COL4A1 COL4A2 COL6A1 ID4 PGR	1.17e-04	174	122	5	91fc1f1c891f105a91968c22e2de5321c52b439a
ToppCell	Somatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_2\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	COL6A1 COL22A1 GRM7 DNAH14 SMYD2	1.17e-04	174	122	5	b3cd22e717d178269e6d5bd5ed7b2d945cd8ea25
ToppCell	BAL-Mild-Myeloid-MoAM-MoAM4\|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)	DMBX1 GSDME AK4 HS3ST2 EPB42	1.17e-04	174	122	5	9191f6abb37ca65da5105f91e21689d11ec1059b
ToppCell	tumor_Lymph_Node_/_Brain-Fibroblasts-Smooth_muscle_cells\|tumor_Lymph_Node_/_Brain / Location, Cell class and cell subclass	COL4A1 COL4A2 COL6A1 PGR CNTFR	1.21e-04	175	122	5	fed9e4120c758fdcc23bb248d1801002b0e0d485
ToppCell	BAL-Mild-Myeloid-MoAM-MoAM4\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	DMBX1 GSDME AK4 HS3ST2 EPB42	1.21e-04	175	122	5	b2099b4ab1bf74497f454a99fffe5f5561b1f968
ToppCell	BAL-Mild-Myeloid-MoAM-MoAM4-\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	DMBX1 GSDME AK4 HS3ST2 EPB42	1.21e-04	175	122	5	6e54b74c735f249c7bfab7087c1638065ec1dd2e
ToppCell	NS-moderate-d_07-13-Lymphoid-NK\|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	COL4A1 COL4A2 COL6A1 BCAN DCHS1	1.21e-04	175	122	5	f6cd24d22f62469319f9d244e3e5de527d3d4d94
ToppCell	390C-Fibroblasts-Fibroblast-B_(Myofibroblast)\|390C / Donor, Lineage, Cell class and subclass (all cells)	COL6A1 GSDME GLIS2 ELN HS3ST2	1.24e-04	176	122	5	852d3da0907fe87c0ef23d75a63ce07619cf0c54
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_3\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	CUBN ADORA2A-AS1 AK4 GLIS1 PDZD2	1.24e-04	176	122	5	1595dbeee336a81e581325d63208ec6262664ee9
ToppCell	390C-Fibroblasts-Fibroblast-B_(Myofibroblast)-\|390C / Donor, Lineage, Cell class and subclass (all cells)	COL6A1 GSDME GLIS2 ELN HS3ST2	1.24e-04	176	122	5	d2df1e435996c51213e88270af9f928e9e09a6f5
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-Adaptive_/_Maladaptive_/_Repairing_Fibroblast\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	COL6A1 GRM7 PGR ELN CNTFR	1.27e-04	177	122	5	9ec7f1e64312d26d434b3312b58386715dbad644
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	COL6A1 GRM7 PGR ELN CNTFR	1.27e-04	177	122	5	016277dfd59b1793fddaaadc2b3f41622d76ce3a
ToppCell	3'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-pericyte_cell-Pericytes-Pericytes_L.2.3.1.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	COL4A1 COL4A2 ADGRA2 IER5L TACC1	1.27e-04	177	122	5	452ec2df36c6d656a7cdadc55be545ccdb146a29
ToppCell	TCGA-Ovary-Primary_Tumor-Ovarian_Carcinoma-Serous_Cystadenocarcinoma-6\|TCGA-Ovary / Sample_Type by Project: Shred V9	COL6A1 ADGRA2 ZNF469 DCHS1 MEGF10	1.31e-04	178	122	5	142879e9393e721f9b05a6bb46995c9d6d713c95
ToppCell	TCGA-Colorectal-Primary_Tumor-Colorectal_Adenocarcinoma-Rectal_Adenocarcinoma-7\|TCGA-Colorectal / Sample_Type by Project: Shred V9	COL4A1 COL4A2 NRXN2 GLIS2 ELN	1.31e-04	178	122	5	edc76b8f15056ec1c9a1c61a048b6331a92592d6
ToppCell	COVID-19-kidney-PCT-S1/S2\|COVID-19 / Disease (COVID-19 only), tissue and cell type	CUBN USH1C ADORA2A-AS1 AK4 GLIS1	1.31e-04	178	122	5	23a12d3d971b857d5be8e907334d1f6b49eeeb32
ToppCell	metastatic_Brain-T/NK_cells-Exhausted_Tfh\|T/NK_cells / Location, Cell class and cell subclass	RTL10 RCC2 ZFHX3 IRS2 ANKRD16	1.31e-04	178	122	5	9a3581a0158dfa5a1cc942f8c532afb5e38b272a
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_2\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	COL6A1 COL22A1 GRM7 DNAH14 SMYD2	1.34e-04	179	122	5	8766a5a066091879f521acfc612abf563ff78808
ToppCell	droplet-Lung-immune-endo-depleted-3m-Myeloid-lung_macrophage\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RAD51B CD163 CABLES1 GLIS2 C1QA	1.34e-04	179	122	5	2c3abd646d2c8992e8ff76a824eab5beba8ba4c6
ToppCell	COPD-Stromal-SMC\|COPD / Disease state, Lineage and Cell class	COL4A1 COL4A2 COL6A1 ID4 ELN	1.34e-04	179	122	5	5c705627bd13a5b2c7b0062fb3d94e4eb1589327
ToppCell	droplet-Lung-immune-endo-depleted-3m-Myeloid-Interstitial_Macrophage\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RAD51B CD163 CABLES1 GLIS2 C1QA	1.34e-04	179	122	5	6eb84fe9691ad40127b2d1f1c672428333c8fab4
Drug	hydroxylysine	COL4A1 COL4A5 COL6A1 GCDH COL22A1 C1QA ELN	1.71e-06	109	119	7	CID000001029
Drug	NS-105	MAP4 GRM4 GRM7	1.63e-05	10	119	3	CID000198695
Drug	cyclobutylene AP5	MAP4 GRM4 GRM7	2.23e-05	11	119	3	CID000126582
Drug	AC1Q6PCP	COL4A1 COL4A5 COL6A1 AVP COL22A1 PGR GSDME OSBPL5	2.88e-05	230	119	8	CID000005267
Drug	malotilate	COL4A1 COL4A5 COL6A1 INTU COL22A1	3.54e-05	71	119	5	CID000004006
Drug	BAPN	COL4A1 COL4A5 COL6A1 COL22A1 ELN	3.54e-05	71	119	5	CID000001647
Drug	GK-101	COL4A1 COL4A5 COL6A1 COL22A1	3.67e-05	36	119	4	CID000161853
Drug	AC1NSKBB	MAP4 GRM4 GRM7	3.83e-05	13	119	3	CID005311256
Drug	MTPG	MAP4 GRM4 GRM7	4.86e-05	14	119	3	CID005311456
Drug	Selara	COL4A1 COL4A5 COL6A1 COL22A1 HCN2 PGR	5.08e-05	125	119	6	CID000150310
Drug	irinotecan HCl; Up 200; 100uM; MCF7; HT_HG-U133A	AMH PIM2 IRF7 XPC MAP3K12 ARID5A CCDC88C	5.43e-05	185	119	7	7498_UP
Drug	C768-0445; Up 200; 10uM; MCF7; HT_HG-U133A_EA	IMPG1 ANKMY1 GRM4 CBLB FGF23 ZFP36L2 IRS2	6.02e-05	188	119	7	865_UP
Drug	DMSe	COL4A1 COL4A5 COL6A1 COL22A1 TPRX1 ELN	6.88e-05	132	119	6	CID000020796
Drug	Isoquinoline, 6,7-dimethoxy-1-methyl-1,2,3,4-tetrahydro, hydrochloride; Down 200; 16.4uM; MCF7; HT_HG-U133A	RAD51B RNF31 GCDH CUL7 MAP3K12 ZFHX3 NAGPA	7.33e-05	194	119	7	2824_DN
Drug	Ungerine nitrate; Down 200; 10.2uM; MCF7; HT_HG-U133A	COL6A1 MAP4 DNAJC16 ID4 ANKMY1 ZFP36L2 IRS2	7.33e-05	194	119	7	6076_DN
Drug	ethylglutamate	MAP4 GRM4 GRM7	7.42e-05	16	119	3	CID000014241
Drug	ionomycin calcium salt; Up 200; 2uM; MCF7; HT_HG-U133A_EA	RAD51B COL6A1 IMPG1 C15orf39 GRM4 MAP3K12 PGR	7.57e-05	195	119	7	871_UP
Drug	prochlorperazine dimaleate salt; Down 200; 10uM; HL60; HT_HG-U133A	COL4A2 MAP4 GCDH MBD3 ZNF771 ZFP36L2 RPAP2	7.57e-05	195	119	7	6174_DN
Drug	Nitrofurantoin [67-20-9]; Down 200; 16.8uM; MCF7; HT_HG-U133A	RAD51B PIM2 MAP4 CUL7 FGF23 ZFP36L2 RPAP2	7.82e-05	196	119	7	4697_DN
Drug	Chelidonine monohydrate (+) [476-32-4]; Down 200; 10.8uM; PC3; HT_HG-U133A	COL6A1 MAP4 GATA3 ODF2 MBD3 LYPD3 TBX6	7.82e-05	196	119	7	5760_DN
Drug	Metoclopramide monohydrochloride [7232-21-5]; Down 200; 11.8uM; PC3; HT_HG-U133A	RAD51B COL6A1 GATA3 TRIOBP ANKMY1 CUL7 MAP3K12	8.07e-05	197	119	7	3728_DN
Drug	Aminopurine, 6-benzyl [1214-39-7]; Up 200; 17.8uM; HL60; HT_HG-U133A	COL6A1 GRM4 GRM7 PPP1R26 ZNF771 FGF23 TBX6	8.07e-05	197	119	7	2351_UP
Drug	Chlorogenic acid [327-97-9]; Down 200; 11.2uM; PC3; HT_HG-U133A	COL6A1 LAMB4 GATA3 GRM4 MBD3 FGF23 ZFP36L2	8.07e-05	197	119	7	4024_DN
Drug	Sulfasalazine [599-79-1]; Up 200; 10uM; MCF7; HT_HG-U133A	MAP4 DNAJC16 CUBN GRM4 MBD3 PDZD2 TBX6	8.33e-05	198	119	7	5446_UP
Drug	Etodolac [41340-25-4]; Down 200; 14uM; MCF7; HT_HG-U133A	RAD51B TRIOBP IRF7 ZFP36L2 LYPD3 ZFHX3 NAGPA	8.33e-05	198	119	7	7006_DN
Drug	(+,-)-Octopamine hydrochloride [770-05-8]; Down 200; 21uM; HL60; HT_HG-U133A	MAP4 RTL10 GCDH IRF7 CCDC88C ZFP36L2 ZFHX3	8.33e-05	198	119	7	3112_DN
Drug	Chlorzoxazone [95-25-0]; Down 200; 23.6uM; PC3; HT_HG-U133A	COL6A1 PIM2 RNF31 MAP4 XPC ZNF512B RPAP2	8.33e-05	198	119	7	2100_DN
Drug	Imipenem [74431-23-5]; Down 200; 13.4uM; PC3; HT_HG-U133A	COL6A1 PIM2 ODF2 MAP3K12 ZNF512B ZFP36L2 RPAP2	8.33e-05	198	119	7	7294_DN
Drug	Iodixanol [92339-11-2]; Down 200; 2.6uM; HL60; HT_HG-U133A	COL4A1 MAP4 RTL10 ID4 ZNF771 ZFHX3 TBX6	8.33e-05	198	119	7	3023_DN
Drug	rosiglitazone; Down 200; 10uM; HL60; HT_HG-U133A	RAD51B COL4A2 LAMB4 MAP4 MBD3 ZNF512B ELN	8.60e-05	199	119	7	2693_DN
Drug	Suxibuzone [27470-51-5]; Up 200; 9.2uM; MCF7; HT_HG-U133A	COL6A1 MAP4 TRIOBP C15orf39 MBD3 DCHS1 CNTFR	8.60e-05	199	119	7	7163_UP
Drug	Adrenosterone [382-45-6]; Down 200; 13.4uM; PC3; HT_HG-U133A	RAD51B PIM2 ODF2 MAP3K12 MBD3 FGF23 ZFHX3	8.60e-05	199	119	7	5045_DN
Drug	Benzylpenicillin sodium [69-57-8]; Down 200; 11.2uM; MCF7; HT_HG-U133A	RAD51B RNF31 MAP4 C15orf39 ANKMY1 IRS2 TBX6	8.87e-05	200	119	7	3577_DN
Drug	DL-penicillamine	COL4A1 COL4A5 COL6A1 COL22A1 MBD3 ELN	9.16e-05	139	119	6	CID000004727
Drug	Madecassol	COL4A1 COL4A5 COL6A1 COL22A1	9.77e-05	46	119	4	CID000108062
Drug	4-hydroxyproline	COL4A1 COL4A5 COL6A1 COL22A1 ELN	1.16e-04	91	119	5	CID000000825
Disease	Developmental Porencephaly	COL4A1 COL4A2	1.64e-05	2	120	2	C4082301
Disease	Congenital porencephaly	COL4A1 COL4A2	1.64e-05	2	120	2	C0302892
Disease	PORENCEPHALY, FAMILIAL	COL4A1 COL4A2	1.64e-05	2	120	2	C1867983
Disease	Porencephaly, Type 1, Autosomal Dominant	COL4A1 COL4A2	1.64e-05	2	120	2	C4551998
Disease	Post-traumatic Porencephaly	COL4A1 COL4A2	1.64e-05	2	120	2	C3698507
Disease	Porencephaly	COL4A1 COL4A2	1.64e-05	2	120	2	C4082173
Disease	HEMORRHAGE, INTRACEREBRAL, SUSCEPTIBILITY TO	COL4A1 COL4A2	1.64e-05	2	120	2	C3281105
Disease	Hemorrhage, intracerebral, susceptibility to	COL4A1 COL4A2	4.91e-05	3	120	2	cv:C3281105
Disease	HEMORRHAGE, INTRACEREBRAL, SUSCEPTIBILITY TO	COL4A1 COL4A2	4.91e-05	3	120	2	614519
Disease	mean platelet volume	COL4A1 RAD51B ZAN ATG14 ANKMY1 RCC2 CABLES1 ZNF512B OTP GLIS2 IRS2 ZNF367 TBX6	2.69e-04	1020	120	13	EFO_0004584
Disease	Hematuria	COL4A1 COL4A5	5.80e-04	9	120	2	C0018965
Disease	hearing impairment	COL4A5 TRIOBP USH1C GSDME	7.00e-04	98	120	4	C1384666
Disease	creatinine measurement	COL4A2 INTU UNCX DNAJC16 CUBN CBLB NRXN2 ZFP36L2 LIPH SP6 ZFHX3 MEGF10	7.57e-04	995	120	12	EFO_0004518
Disease	endometrial carcinoma, endometriosis	AXIN2 PGR	8.81e-04	11	120	2	EFO_0001065, EFO_1001512
Disease	myopathy (implicated_via_orthology)	COL4A1 COL4A5 MEGF10	9.93e-04	48	120	3	DOID:423 (implicated_via_orthology)
Disease	collagen disease (implicated_via_orthology)	COL4A1 COL4A5	1.05e-03	12	120	2	DOID:854 (implicated_via_orthology)
Disease	cortical surface area measurement	RAD51B INTU ZAN TRIOBP COL22A1 ADGRA2 CCDC88C ZNF469 GLIS2 DMRTA2 ZFHX3 TACC1 PDZD2 TBX6	1.15e-03	1345	120	14	EFO_0010736
Disease	intraocular pressure measurement	COL4A1 RAD51B COL6A1 RTL10 TRIOBP ZNF469 ZFP36L2 ZFHX3	1.16e-03	509	120	8	EFO_0004695
Disease	survival time, breast carcinoma	RAD51B ZFHX3	1.24e-03	13	120	2	EFO_0000305, EFO_0000714
Disease	body surface area	RAD51B COL6A1 UNCX CABLES1 AXIN2 GLIS2 OSBPL5 ZFHX3 DOT1L	1.28e-03	643	120	9	EFO_0022196
Disease	Familial thoracic aortic aneurysm and aortic dissection	COL4A1 COL4A5 ELN	1.32e-03	53	120	3	C4707243
Disease	Small cell carcinoma of lung	COL4A2 AVP COL22A1	1.40e-03	54	120	3	C0149925
Disease	mean reticulocyte volume	RAD51B INTU C15orf39 GCDH FBXO38 ZNF469 IER5L AK4 IRS2 TBX6	1.60e-03	799	120	10	EFO_0010701
Disease	hepatoblastoma (is_marker_for)	AXIN2 ZFHX3	1.66e-03	15	120	2	DOID:687 (is_marker_for)
Disease	body weights and measures, body height	ID4 CABLES1	1.66e-03	15	120	2	EFO_0004324, EFO_0004339
Disease	cortical thickness	RAD51B COL4A2 INTU TRIOBP USH1C ADGRA2 ZNF469 PROX2 GLIS2 TACC1 ELN PDZD2	1.96e-03	1113	120	12	EFO_0004840
Disease	chronic obstructive pulmonary disease	RAD51B COL4A2 ID4 BCL9 FBXO38 PROX2 ELN DOT1L PDZD2	2.04e-03	688	120	9	EFO_0000341
Disease	non-lobar intracerebral hemorrhage	COL4A1 COL4A2 DNAH14	2.18e-03	63	120	3	EFO_0010178
Disease	leukemia (implicated_via_orthology)	MEIS3P2 DOT1L	2.68e-03	19	120	2	DOID:1240 (implicated_via_orthology)
Disease	urinary microalbumin measurement	CUBN PPM1H	2.97e-03	20	120	2	EFO_0010967
Disease	corneal hysteresis	COL6A1 ZNF469	2.97e-03	20	120	2	EFO_0010066
Disease	Hereditary hearing loss and deafness	COL4A5 TRIOBP USH1C GSDME	3.03e-03	146	120	4	cv:C0236038
Disease	Primary microcephaly	PHC1 TUBGCP6	3.59e-03	22	120	2	C0431350
Disease	glomerular filtration rate, renal transplant outcome measurement, donor genotype effect measurement	COL4A1 TPRX1	3.59e-03	22	120	2	EFO_0005199, EFO_0005208, EFO_0007892
Disease	Nonsyndromic genetic hearing loss	TRIOBP USH1C GSDME	3.72e-03	76	120	3	cv:C5680182

Protein segments in the cluster

Peptide	Gene	Start	Entry
GLGCSISSGPIQKPG	USH1C	221	Q9Y6N9
ESCDPSLGLAGPGAK	TACC1	76	O75410
GGPAALCGATFKPVR	AMER3	76	Q8N944
PSAPNGGGVLGSCDL	EPB42	351	P16452
AKPAGSGLVSCLLGP	ARID5A	476	Q03989
LQAAGGCPGPAGDTL	ANKRD16	26	Q6P6B7
GDGICVSRGKAPSSP	BLACE	76	A4D250
CRAPDGKKGEAGRPG	C1QA	26	P02745
GKGARALEAPGCGPR	ATG14	6	Q6ZNE5
CSGERPKGLSGGVPG	ADGRA2	46	Q96PE1
KRGTHSCGPRESGGP	DNAH10OS	141	P0CZ25
PLDLAASPGLCGGGL	CALHM3	311	Q86XJ0
PVHGRGSEGKPCGEL	GRM4	56	Q14833
SLQGGCPGPEDAGSK	GSDME	366	O60443
KPCSNGGPAAAGEGR	ADORA2A-AS1	101	P86434
TCGGKPAERGPLAGH	RTL10	71	Q7L3V2
SLAKGARGDPGFPGA	COL4A2	356	P08572
MLTCKRPSGGGDAGP	COX10	426	Q12887
AASPGACPLLGGKGF	AXIN2	491	Q9Y2T1
GKEAGEGGLPLCGPT	DOT1L	1386	Q8TEK3
PLARASKEAGGSCPG	DMRTA2	251	Q96SC8
EGRGALSSGPEGLCP	DCUN1D3	286	Q8IWE4
GIPGCNGTKGERGPL	COL4A1	121	P02462
PGGPLRATLSGCHKG	NWD1	856	Q149M9
GSLTEITGPPGCGKT	RAD51B	101	O15315
GAPGGGKRAARPATA	RCC2	61	Q9P258
RCAKAAPSGPGTEGG	SLC16A8	436	O95907
NPGKRGPVGDCTGTL	MEGF10	966	Q96KG7
VTPSQRCGGGLPGVK	BCAN	316	Q96GW7
SEEGSGPLISGCGPL	FHIP1B	956	Q8N612
GESAGPGPRALGCLV	DCHS1	2541	Q96JQ0
GPPATATAFLGGCGL	DCHS1	3111	Q96JQ0
GAPRCLRGPSAGGQK	HS3ST2	51	Q9Y278
VKTEGGGSEAPLCPG	MAP4	1086	P27816
LPKGLQGVGPGCTDE	MBD3	161	O95983
AVCPGEGTGSGGLLP	GPR179	2181	Q6PRD1
SLDGLEPGLCGPGTK	IMPG1	721	Q17R60
LGPPGSGKGTVCQRI	AK4	11	P27144
EVSGCGSLRAPGPGL	LRRC47	56	Q8N1G4
GCRLLGEGSPKPGIT	CBLB	606	Q13191
DGVPGQGCSEGLPAK	CCDC88C	1966	Q9P219
GNRACPGGSGPKTSA	PDZD2	2536	O15018
CPPRGLVSSLGKGSA	CUL7	1601	Q14999
PGSLLPGGKGRCLSS	NSUN5P2	286	Q63ZY6
VGCAPSKGPETLFAG	NRXN2	801	Q9P2S2
GESRGKPSCGLGSRP	DNAJC16	736	Q9Y2G8
TCGGGPRAAFPTGVK	TUBGCP6	486	Q96RT7
APLGCVAAPGGLLGS	IL10RA	546	Q13651
RLLALCPGGPGGLGD	AMH	406	P03971
GGLDQPGCPKTILGG	LIPH	226	Q8WWY8
EGLPLTGACAGGPGL	IRF7	216	Q92985
PGPLDLSALACGNGG	GLIS2	376	Q9BZE0
GRKAPSGCGGGELAL	ID4	11	P47928
PAGCGGKGRGLLLPA	MSL1	71	Q68DK7
LAGPGCKAGLSPAEP	MED26	351	O95402
SLAVRGCGSGLPGKN	LYPD3	76	O95274
CSPRDGAGAGLGTPR	MEIS3P2	81	A8K0S8
EAGGCASKAIGSPGP	INTU	606	Q9ULD6
PRDTAQGPGGCGTGK	PROX2	156	Q3B8N5
KAPGASGCLLPRDGL	PGR	481	P06401
EPPKGCARVGLSAGT	FBXO38	466	Q6PIJ6
SGGCGGRGSKVALLP	IRS2	406	Q9Y4H2
PTIAPGACGGFLRTG	CUBN	1971	O60494
PSSLLGGSPTGFGCK	GATA3	236	P23771
LLPSACPERGGGAGG	APC2	1296	O95996
LKSTTPGGALPECFG	ICE1	1051	Q9Y2F5
GTPAAGLAAGSGPCL	CABLES1	126	Q8TDN4
GLPGCKGSPGFDGIQ	COL6A1	341	P12109
VLPGASSLGGPFGCL	GCDH	276	Q92947
GLGCGLKNRSSEGPS	CD19	131	P15391
PGADSKGLGCKRGSP	DMBX1	216	Q8NFW5
AGGTGPEGCRPFAKF	FGF23	236	Q9GZV9
SSADAALCKPGGPGG	BCL9	1186	O00512
IPGCNGTKGERGFPG	COL4A5	121	P29400
TTKICDPGELGSGGG	CNTFR	331	P26992
AILEGKRSGFAPCGP	ANKMY1	241	Q9P2S6
QCVKGDRGAPGIPGS	COL22A1	1021	Q8NFW1
LNLGGCPAGPAGTGK	DNAH14	1156	Q0VDD8
PKLDAALSGVGLPGC	MAP3K12	516	Q12852
KGLASPPGGGCISFS	FOXD4L1	311	Q9NU39
GPSGVPCGDIKRENG	GRM7	61	Q14831
PLPCGGALCTGRKGH	LAMB4	1386	A4D0S4
SDGKGGCGLGQELLP	GLIS1	386	Q8NBF1
CGVALSTPGGARFGK	CD163	626	Q86VB7
GLSPIFPGGACLGKA	ELN	766	P15502
GPARGPKVSFSCRGA	HCN2	116	Q9UL51
PAGGAGALSELPGCA	IER5L	146	Q5T953
AVKCRLGVGGSDPGG	OTP	26	Q5XKR4
SGGSPRFPSCGKNGV	ODF2	6	Q5BJF6
GTCKPGRDGEPGTSP	OSBPL5	251	Q9H0X9
GPPGTGKTLCARAVA	PSMC2	216	P35998
SALCGGKQEAGDSPP	TAF6	641	P49848
GCGPGGADSSKPRIL	RRAGC	51	Q9HB90
EKGPLGEGPSRCFFG	PIM2	131	Q9P1W9
LRTFSVLEPGGPGGC	NAGPA	101	Q9UK23
AGGGSRCKPEPAHGS	PPP1R26	166	Q5T8A7
AERLGAPCGPDGGKK	SP6	236	Q3SY56
ELGGPSGPGSSRLCL	SOWAHD	96	A6NJG2
GCGEPSLGAAKAPEG	TRIOBP	1461	Q9H2D6
KGCRGTLPAQEGPSG	C15orf39	546	Q6ZRI6
PRGCKGLGLGTEGPQ	RNF31	326	Q96EP0
PPGGKGEGTVCSRLP	TTLL8	746	A6PVC2
GCRAQKGIPAALSPG	TPRX1	81	Q8N7U7
GCGRDFKLPPGATAA	ZNF771	291	Q7L3S4
GGGSCGGSDLPLRFP	PPM1H	26	Q9ULR3
GPSSAGRKAGAPRCS	RPAP2	6	Q8IXW5
APGAVCSPGESKELG	TNKS1BP1	1291	Q9C0C2
LELRQCLPCGPGGKG	AVP	36	P01185
GGSCPRKGTGVVQPL	PHC1	301	P78364
TPGGPCDSTLGGDIR	TBX6	306	O95947
GVEEAGGPPASLCKL	ZBTB47	196	Q9UFB7
GGPPASLCKLEGGEE	ZBTB47	201	Q9UFB7
APSLPGKGSGCSVAL	ZNF469	1511	Q96JG9
GGLGGQLPASPSCRD	ZNF469	2116	Q96JG9
CVGGRRLPGSSKSGP	ZNF512B	6	Q96KM6
PPSCVKGSGLGAGQG	XP32	11	Q5T750
EDAPSLLPGGGVSCK	SP140	211	Q13342
RKRGCSHPGGSADGP	XPC	56	Q01831
RTTPIKPTCGGGGEP	ZNF367	36	Q7RTV3
LGGLERFCSPGKGRG	SMYD2	6	Q9NRG4
GTGGAEDLLAPGAPC	ZFP36L2	336	P47974
NPGDDGCLLKQGPRG	nan	111	Q8N7P7
PAACGVGGDGQPFKL	UNCX	76	A6NJT0
GAGGKQGDPSCAAPV	ZFHX3	176	Q15911
PLDTLKGLGTCFPSG	WDR36	31	Q8NI36
KGLGTCFPSGPELRG	WDR36	36	Q8NI36
LPESSEPGCFLVGGK	ZAN	1711	Q9Y493
GTAFGSAGLGPKCPS	KRT72	76	Q14CN4