Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionbHLH transcription factor binding

BHLHE41 ASCL1

1.49e-0437102GO:0043425
GeneOntologyMolecularFunctionE-box binding

BHLHE41 ASCL1

4.07e-0461102GO:0070888
GeneOntologyMolecularFunctionDNA-binding transcription repressor activity, RNA polymerase II-specific

FOXK1 BHLHE41 ASCL1

4.50e-04320103GO:0001227
GeneOntologyMolecularFunctionDNA-binding transcription repressor activity

FOXK1 BHLHE41 ASCL1

4.75e-04326103GO:0001217
Domain-

BHLHE41 ASCL1

1.18e-03109924.10.280.10
DomainHLH

BHLHE41 ASCL1

1.23e-0311192PF00010
DomainHLH

BHLHE41 ASCL1

1.34e-0311692SM00353
DomainBHLH

BHLHE41 ASCL1

1.36e-0311792PS50888
DomainbHLH_dom

BHLHE41 ASCL1

1.38e-0311892IPR011598
PathwayREACTOME_BMAL1_CLOCK_NPAS2_ACTIVATES_CIRCADIAN_GENE_EXPRESSION

BHLHE41 AVP

7.38e-052772M26943
PathwayWP_SIDS_SUSCEPTIBILITY_PATHWAYS

AVP ASCL1

3.57e-045972MM15838
PathwayREACTOME_CIRCADIAN_CLOCK

BHLHE41 AVP

5.02e-047072M938
GeneFamilyBasic helix-loop-helix proteins

BHLHE41 ASCL1

7.55e-0411072420
ToppCellCerebellum-Macroglia-ASTROCYTE-Gja1-Bergmann_Glia_(Slc1a3)--|Cerebellum / BrainAtlas - Mouse McCarroll V32

TULP2 RPE65

1.68e-04881022075743c7c0b6d74e80464a6bc776206d744d502
ToppCellCerebellum-Macroglia-ASTROCYTE-Gja1-Bergmann_Glia_(Slc1a3)|Cerebellum / BrainAtlas - Mouse McCarroll V32

TULP2 RPE65

1.68e-0488102a49319bc97188550e08248973e10c626124c3917
ToppCellCerebellum-Macroglia-ASTROCYTE-Gja1-Bergmann_Glia_(Slc1a3)-|Cerebellum / BrainAtlas - Mouse McCarroll V32

TULP2 RPE65

1.68e-048810214b11249a2b3fa327622897fe74630c2697ea47e
ToppCellPosterior_cortex-Neuronal-Excitatory-eN1(Slc17a7)-eN1_1-Calb1|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

AVP NPTXR

3.13e-04120102a6d0406a174d46ce06b41280292931954af88a59
ToppCellHippocampus-Neuronal-Excitatory-eN1(Slc17a7)-eN1_2-Pvrl3|Hippocampus / BrainAtlas - Mouse McCarroll V32

MYO15A NPTXR

3.51e-041271029bc55cb9f4bddb274930784d12a83b9dceb35cb7
ToppCell356C-Fibroblasts-Fibroblast-H|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

MYO15A NPTXR

4.95e-0415110222afd8201eff8471da3456be065f2790de5e4bfe
ToppCell356C-Fibroblasts-Fibroblast-H-|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

MYO15A NPTXR

4.95e-041511022dc132895609e4efe17954e31f53d9c1ccf256ef
ToppCell367C-Fibroblasts-Fibroblast-D-|367C / Donor, Lineage, Cell class and subclass (all cells)

TULP2 ASCL1

5.14e-04154102dd3d34f065820e706515a13619f19a5b12734c8e
ToppCell367C-Fibroblasts-Fibroblast-D|367C / Donor, Lineage, Cell class and subclass (all cells)

TULP2 ASCL1

5.14e-041541024bfda1c41efbb86d829b3797d1168bf2587c3c97
ToppCellprimary_visual_cortex-Neuronal-glutamatergic_neuron-L2/3_IT|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

AVP NPTXR

5.62e-04161102e3327c296d48e821004e61a573abb75624a6f040
ToppCell5'-Adult-SmallIntestine-Hematopoietic-Plasma_cells-IgG_plasma_cell|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

BHLHE41 ASCL1

5.90e-041651029e2fa634f4749e35aa5dca43476477b5d362afd7
ToppCellBrain_organoid-organoid_Kanton_Nature-Organoid-4M-Radial_glial-RGCs_early_2|Organoid-4M / Sample Type, Dataset, Time_group, and Cell type.

BHLHE41 RPE65

5.90e-04165102e460e03992781073cd836a655f15dda3157cea55
ToppCell367C-Myeloid-Dendritic-pDC|367C / Donor, Lineage, Cell class and subclass (all cells)

AVP TULP2

6.04e-04167102650de8cd5df070639b8aa292aacead739cfdb02c
ToppCell3'-Distal_airway-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.2.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MYO15A KLKB1

6.12e-04168102de0b00bc405c898d08a06b2e585fb62c0ab9a66e
ToppCell5'-GW_trimst-2-LargeIntestine-Neuronal-Glial_immature-ENCC/glia_Progenitor|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

NPTXR ASCL1

6.12e-04168102948d9e9972bd2a4b503d55fa69b70dd568a35a67
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_PAX6-Inh_L1-3_PAX6_NABP1|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

RPE65 ASCL1

6.19e-041691023efaef30b4b1d0e79055f78aab1f230ec8d83450
ToppCell15-Airway-Epithelial-Submucosal_gland_basal|Airway / Age, Tissue, Lineage and Cell class

RPE65 KLKB1

6.26e-0417010261f8dd5e27df1b8d01ccfd0d25247b34aa8d182c
ToppCellfacs-Brain_Non-Myeloid-Striatum-24m-Macroglial-Oligodendrocyte_progenitor_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NPTXR ASCL1

6.48e-041731022b448acd5e584f24567204c31b8d74715e92f32a
ToppCellfacs-Brain_Non-Myeloid-Striatum-24m-Macroglial-oligodendrocyte_precursor_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NPTXR ASCL1

6.48e-041731025086edc29c5a6137ca09877929a1317f9739c801
ToppCell3'-GW_trimst-1.5-LargeIntestine-Neuronal-neurons_B-Branch_B1_(eMN)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MYO15A ASCL1

6.56e-04174102271c51d220842402975d97c86c9acfdbdf62a32c
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_5-Exc_L4-5_RORB_LINC01474|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

NPTXR ASCL1

6.63e-04175102030f93af5a96848b9118e2a8116e19ddae438d92
ToppCellChildren_(3_yrs)|World / Lineage, Cell type, age group and donor

BHLHE41 TULP2

6.86e-04178102df2ecd3214590b914f2762db57efe780ba038db3
ToppCellfacs-Large_Intestine-Proximal-24m-Epithelial-enteroendocrine_cell|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BHLHE41 AVP

7.41e-041851022a8104f610fa5ce618f8105521616722462a0d42
ToppCellmild-unassigned|mild / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

FOXK1 NPTXR

7.48e-041861025b2e1a58916f392fa1156bf9210df528775248ff
ToppCellNeuroendocrine-neuroendo-2-Calca|World / Class top

BHLHE41 ASCL1

7.73e-041891026baa9a74560121cc008bb8fa9b2b7a335b3aeee0
ToppCellNeuroendocrine|World / Class top

BHLHE41 ASCL1

7.97e-041921020199da3ef9ddb6673e9aa41f346f374838aec182
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-TAM-BDM-TAM-BDM_INF-G|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

BHLHE41 KLKB1

7.97e-04192102935a4a36881a9fa4daa02cba96af07f6686ed8d6
ToppCellBrain_organoid-organoid_Velasco_nature-6_mon-Radial_glial-RG|6_mon / Sample Type, Dataset, Time_group, and Cell type.

BHLHE41 ASCL1

7.97e-04192102ee822325bb32ac7ad1eeccc23d966367e90a9edd
ToppCellFetal_brain-fetalBrain_Zhong_nature-GW10-Myeloid|GW10 / Sample Type, Dataset, Time_group, and Cell type.

BHLHE41 TULP2

8.14e-041941024f28841c7f37884fc34c6689cd6976c6559d23f1
ToppCellFetal_brain-fetalBrain_Zhong_nature-GW10-Myeloid-Microglia|GW10 / Sample Type, Dataset, Time_group, and Cell type.

BHLHE41 TULP2

8.14e-04194102459e836bcdb6742333684ac23d960efa5e99702f
ToppCellmLN-T_cell-Th1|T_cell / Region, Cell class and subclass

BHLHE41 TULP2

8.39e-041971025e39a49dddef04469ff2b615d755ddf6a926e58e
ToppCellLPS_only-Epithelial_alveolar-AT_1-Differentiating_AT2|LPS_only / Treatment groups by lineage, cell group, cell type

MYO15A RPE65

8.39e-041971026b6504c47c309bac4f790e2f372d454bbdea49e8
ToppCellTransverse-(2)_B_cell-(21)_B_cell_IgG_Plasma|Transverse / shred on region, Cell_type, and subtype

BHLHE41 ASCL1

8.47e-04198102d6052b5a44246798e90f4779cd940ffac7539fcd
ToppCellTransverse-B_cell-B_cell_IgG_Plasma|Transverse / Region, Cell class and subclass

BHLHE41 ASCL1

8.47e-04198102a4ece1fe3d15acfde0e6ff14cddb3a3d16f61ce0
ToppCellmild-unassigned|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

FOXK1 NPTXR

8.64e-04200102ca0a08bf162c954f037a56aa0cbb8b5d7c6ffec0
Drug6-Ketoprostaglandin F1 alpha

AVP KLKB1

1.58e-0514102ctd:D015121
DrugTrifluridine [70-00-8]; Up 200; 13.6uM; PC3; HT_HG-U133A

MYO15A NPTXR ASCL1

7.10e-051951035819_UP
DrugAC1N4DEC

MYO15A AVP

2.10e-0450102CID000001495
DrugLys-Bradykinin

AVP KLKB1

3.03e-0460102CID000009569
DrugBAEE

AVP KLKB1

3.45e-0464102CID000123880
DrugAC1MO44G

AVP KLKB1

7.12e-0492102CID003363161
Drugmeclofenamate

AVP KLKB1

7.43e-0494102CID000004036
Druggeneticin

AVP RPE65

1.09e-03114102CID000123865
DrugCAS 76095-16-4

AVP KLKB1

1.33e-03126102CID000003222
Druganiracetam

BHLHE41 AVP

1.41e-03130102CID000002196
Drugnoradrealine

AVP KLKB1 ASCL1

1.68e-03575103CID000000951
DiseaseSmall cell carcinoma of lung

AVP ASCL1

1.47e-0454102C0149925
Diseasestem Cell Growth Factor beta measurement

KLKB1 ASCL1

2.83e-0475102EFO_0008292
Diseasecardiac troponin I measurement

FOXK1 KLKB1

1.54e-03176102EFO_0010071

Protein segments in the cluster

PeptideGeneStartEntry
AAAAAPFCLPFCFLS

BHLHE41

341

Q9C0J9
PFCLPFCFLSPSAAA

BHLHE41

346

Q9C0J9
LAACLSGFAPSPCFN

MYO15A

2151

Q9UKN7
FAFCRDCQFPEASPA

PMS2P1

386

A4D2B8
FSRFLCTPLAAACPS

NPTXR

91

O95502
PPAACFFATAAAAAA

ASCL1

26

P50553
CSPVLCAAAAAAAFP

FOXK1

21

P85037
CTFHPRCLLFSFLPA

KLKB1

51

P03952
CAFPDPCKNIFSRFF

RPE65

106

Q16518
DFCFPFSPLQAFSIC

TULP2

501

O00295
LPACFLGLLAFSSAC

AVP

6

P01185