Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	helicase activity	SMARCA5 DDX60 RECQL DDX3X DHX8 DDX46 DDX54 SMARCA1 DDX60L	2.48e-06	158	146	9	GO:0004386
GeneOntologyMolecularFunction	ATP-dependent activity	SMARCA5 ABCA4 HYOU1 MYO7A DDX60 RNF213 RECQL AK9 DNAH7 DDX3X DHX8 DDX46 DNAH12 SLC27A1 DDX54 SMARCA1 DDX60L	2.64e-06	614	146	17	GO:0140657
GeneOntologyMolecularFunction	RNA stem-loop binding	ERVK-7 ERVK-10 DDX3X ERVK-11	1.49e-05	21	146	4	GO:0035613
GeneOntologyMolecularFunction	ATP hydrolysis activity	SMARCA5 ABCA4 DDX60 RNF213 RECQL AK9 DNAH7 DDX3X DHX8 DDX46 DNAH12 DDX54 DDX60L	2.21e-05	441	146	13	GO:0016887
GeneOntologyMolecularFunction	RNA helicase activity	DDX60 DDX3X DHX8 DDX46 DDX54 DDX60L	2.30e-05	78	146	6	GO:0003724
GeneOntologyMolecularFunction	ATP-dependent activity, acting on RNA	DDX60 DDX3X DHX8 DDX46 DDX54 DDX60L	2.65e-05	80	146	6	GO:0008186
GeneOntologyMolecularFunction	RNA-DNA hybrid ribonuclease activity	ERVK-7 ERVK-10 ERVK-11	6.05e-05	11	146	3	GO:0004523
GeneOntologyMolecularFunction	catalytic activity, acting on a nucleic acid	SMARCA5 ERCC4 DDX60 RECQL ERVK-7 ERVK-10 DDX3X DHX8 DDX46 DTWD2 DDX54 MEPCE SMARCA1 DDX60L ERVK-11	7.87e-05	645	146	15	GO:0140640
GeneOntologyMolecularFunction	RNA-directed DNA polymerase activity	ERVK-7 ERVK-10 ERVK-11	1.31e-04	14	146	3	GO:0003964
GeneOntologyMolecularFunction	annealing activity	RECQL DDX3X SMARCA1	1.31e-04	14	146	3	GO:0140666
GeneOntologyMolecularFunction	catalytic activity, acting on RNA	DDX60 ERVK-7 ERVK-10 DDX3X DHX8 DDX46 DTWD2 DDX54 MEPCE DDX60L ERVK-11	2.54e-04	417	146	11	GO:0140098
GeneOntologyMolecularFunction	pyrophosphatase activity	SMARCA5 ABCA4 ENPP1 DDX60 RNF213 RECQL AK9 DNAH7 DDX3X DHX8 GTPBP2 DDX46 DNAH12 GPN2 DDX54 DDX60L	4.33e-04	839	146	16	GO:0016462
GeneOntologyMolecularFunction	hydrolase activity, acting on acid anhydrides	SMARCA5 ABCA4 ENPP1 DDX60 RNF213 RECQL AK9 DNAH7 DDX3X DHX8 GTPBP2 DDX46 DNAH12 GPN2 DDX54 DDX60L	4.38e-04	840	146	16	GO:0016817
GeneOntologyMolecularFunction	hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	SMARCA5 ABCA4 ENPP1 DDX60 RNF213 RECQL AK9 DNAH7 DDX3X DHX8 GTPBP2 DDX46 DNAH12 GPN2 DDX54 DDX60L	4.38e-04	840	146	16	GO:0016818
GeneOntologyMolecularFunction	peptidyl-prolyl cis-trans isomerase activity	RANBP2 RGPD8 PPIB NKTR	4.86e-04	50	146	4	GO:0003755
GeneOntologyMolecularFunction	dinitrosyl-iron complex binding	GSTA1 GSTA2	5.23e-04	5	146	2	GO:0035731
GeneOntologyMolecularFunction	isomerase activity	RANBP2 RGPD8 RECQL PPIB GSTA1 GSTA2 NKTR	5.36e-04	192	146	7	GO:0016853
GeneOntologyMolecularFunction	acyltransferase activity	RNF144B RANBP2 ITCH TRIM2 NAA15 RGPD8 RNF213 CBL DGAT2L6 ARRB1 FBXO3 UHRF1 NAA40 MCAT TAF1L	5.65e-04	775	146	15	GO:0016746
GeneOntologyMolecularFunction	ribonucleoside triphosphate phosphatase activity	SMARCA5 ABCA4 DDX60 RNF213 RECQL AK9 DNAH7 DDX3X DHX8 GTPBP2 DDX46 DNAH12 GPN2 DDX54 DDX60L	5.65e-04	775	146	15	GO:0017111
GeneOntologyMolecularFunction	cis-trans isomerase activity	RANBP2 RGPD8 PPIB NKTR	6.08e-04	53	146	4	GO:0016859
GeneOntologyMolecularFunction	cyclosporin A binding	RANBP2 PPIB NKTR	6.92e-04	24	146	3	GO:0016018
GeneOntologyMolecularFunction	catalytic activity, acting on DNA	SMARCA5 ERCC4 RECQL ERVK-7 ERVK-10 DDX3X SMARCA1 ERVK-11	7.01e-04	262	146	8	GO:0140097
GeneOntologyMolecularFunction	steroid delta-isomerase activity	GSTA1 GSTA2	1.09e-03	7	146	2	GO:0004769
GeneOntologyMolecularFunction	glutathione peroxidase activity	GPX8 GSTA1 GSTA2	1.10e-03	28	146	3	GO:0004602
GeneOntologyCellularComponent	PTW/PP1 phosphatase complex	PPP1CA PPP1CC WDR82	1.17e-05	7	147	3	GO:0072357
Domain	Helicase_C	SMARCA5 DDX60 RECQL DDX3X DHX8 DDX46 DDX54 SMARCA1 DDX60L	1.41e-07	107	144	9	PF00271
Domain	HELICc	SMARCA5 DDX60 RECQL DDX3X DHX8 DDX46 DDX54 SMARCA1 DDX60L	1.41e-07	107	144	9	SM00490
Domain	Helicase_C	SMARCA5 DDX60 RECQL DDX3X DHX8 DDX46 DDX54 SMARCA1 DDX60L	1.53e-07	108	144	9	IPR001650
Domain	HELICASE_CTER	SMARCA5 DDX60 RECQL DDX3X DHX8 DDX46 DDX54 SMARCA1 DDX60L	1.66e-07	109	144	9	PS51194
Domain	HELICASE_ATP_BIND_1	SMARCA5 DDX60 RECQL DDX3X DHX8 DDX46 DDX54 SMARCA1 DDX60L	1.66e-07	109	144	9	PS51192
Domain	DEXDc	SMARCA5 DDX60 RECQL DDX3X DHX8 DDX46 DDX54 SMARCA1 DDX60L	1.66e-07	109	144	9	SM00487
Domain	Helicase_ATP-bd	SMARCA5 DDX60 RECQL DDX3X DHX8 DDX46 DDX54 SMARCA1 DDX60L	1.80e-07	110	144	9	IPR014001
Domain	DEAD/DEAH_box_helicase_dom	DDX60 RECQL DDX3X DHX8 DDX46 DDX54 DDX60L	1.49e-06	73	144	7	IPR011545
Domain	DEAD	DDX60 RECQL DDX3X DHX8 DDX46 DDX54 DDX60L	1.49e-06	73	144	7	PF00270
Domain	TPR_REGION	RANBP2 NAA15 RGPD8 IFT172 P4HA1 CTR9 RGPD5 LRP2BP	4.26e-05	165	144	8	PS50293
Domain	TPR	RANBP2 NAA15 RGPD8 IFT172 P4HA1 CTR9 RGPD5 LRP2BP	4.26e-05	165	144	8	PS50005
Domain	SLIDE	SMARCA5 SMARCA1	5.90e-05	2	144	2	IPR015195
Domain	ISWI_HAND-dom	SMARCA5 SMARCA1	5.90e-05	2	144	2	IPR015194
Domain	SLIDE	SMARCA5 SMARCA1	5.90e-05	2	144	2	PF09111
Domain	HAND	SMARCA5 SMARCA1	5.90e-05	2	144	2	PF09110
Domain	ISWI	SMARCA5 SMARCA1	5.90e-05	2	144	2	IPR029915
Domain	-	SMARCA5 ABCA4 MYO7A DDX60 RNF213 RECQL AK9 DNAH7 DDX3X DHX8 GTPBP2 DDX46 DNAH12 GPN2 DDX54 SMARCA1 DDX60L	6.32e-05	746	144	17	3.40.50.300
Domain	Ran_BP1	RANBP2 RGPD8 RGPD5	9.38e-05	12	144	3	PF00638
Domain	RANBD1	RANBP2 RGPD8 RGPD5	9.38e-05	12	144	3	PS50196
Domain	P-loop_NTPase	SMARCA5 ABCA4 MYO7A GAL3ST1 DDX60 RNF213 RECQL AK9 DNAH7 DDX3X DHX8 GTPBP2 DDX46 DNAH12 GPN2 DDX54 SMARCA1 DDX60L	9.41e-05	848	144	18	IPR027417
Domain	RanBD	RANBP2 RGPD8 RGPD5	1.21e-04	13	144	3	SM00160
Domain	Ran_bind_dom	RANBP2 RGPD8 RGPD5	1.21e-04	13	144	3	IPR000156
Domain	TPR-contain_dom	RANBP2 NAA15 RGPD8 P4HA1 CTR9 RGPD5 LRP2BP	1.64e-04	150	144	7	IPR013026
Domain	STPPase_N	PPP1CA PPP1CC	1.76e-04	3	144	2	IPR031675
Domain	DBINO	SMARCA5 SMARCA1	1.76e-04	3	144	2	IPR020838
Domain	DBINO	SMARCA5 SMARCA1	1.76e-04	3	144	2	PF13892
Domain	STPPase_N	PPP1CA PPP1CC	1.76e-04	3	144	2	PF16891
Domain	Cyclophilin-type_PPIase_CS	RANBP2 PPIB NKTR	3.97e-04	19	144	3	IPR020892
Domain	TPR-like_helical_dom	RANBP2 NAA15 RGPD8 IFT172 P4HA1 CTR9 RGPD5 LRP2BP	4.57e-04	233	144	8	IPR011990
Domain	GST_alpha	GSTA1 GSTA2	5.81e-04	5	144	2	IPR003080
Domain	TPR_repeat	RANBP2 NAA15 RGPD8 P4HA1 CTR9 LRP2BP	5.81e-04	133	144	6	IPR019734
Domain	TPR_2	NAA15 P4HA1 CTR9 LRP2BP	5.93e-04	50	144	4	PF07719
Domain	TPR_2	NAA15 P4HA1 CTR9 LRP2BP	5.93e-04	50	144	4	IPR013105
Domain	Pro_isomerase	RANBP2 PPIB NKTR	6.21e-04	22	144	3	PF00160
Domain	Cyclophilin-type_PPIase_dom	RANBP2 PPIB NKTR	6.21e-04	22	144	3	IPR002130
Domain	Cyclophilin-like_dom	RANBP2 PPIB NKTR	6.21e-04	22	144	3	IPR029000
Domain	CSA_PPIASE_2	RANBP2 PPIB NKTR	6.21e-04	22	144	3	PS50072
Domain	-	RANBP2 PPIB NKTR	6.21e-04	22	144	3	2.40.100.10
Domain	CSA_PPIASE_1	RANBP2 PPIB NKTR	6.21e-04	22	144	3	PS00170
Domain	TPR_1	RANBP2 NAA15 RGPD8 CTR9 RGPD5	6.60e-04	90	144	5	IPR001440
Domain	TPR_1	RANBP2 NAA15 RGPD8 CTR9 RGPD5	6.60e-04	90	144	5	PF00515
Domain	Haem_d1	EML6 KMT2A	8.68e-04	6	144	2	IPR011048
Domain	SANT_dom	SMARCA5 SMARCA1 RERE	1.02e-03	26	144	3	IPR017884
Domain	THIOL_PROTEASE_CYS	CAPN14 CAPN6 CTSW	1.02e-03	26	144	3	PS00139
Domain	THIOL_PROTEASE_ASN	CAPN14 CAPN6 CTSW	1.15e-03	27	144	3	PS00640
Domain	THIOL_PROTEASE_HIS	CAPN14 CAPN6 CTSW	1.15e-03	27	144	3	PS00639
Domain	SANT	SMARCA5 SMARCA1 RERE	1.28e-03	28	144	3	PS51293
Domain	Pept_cys_AS	CAPN14 CAPN6 CTSW	1.28e-03	28	144	3	IPR000169
Domain	DEAD_ATP_HELICASE	DDX3X DDX46 DDX54	1.72e-03	31	144	3	PS00039
Domain	RNA-helicase_DEAD-box_CS	DDX3X DDX46 DDX54	2.07e-03	33	144	3	IPR000629
Domain	Q_MOTIF	DDX3X DDX46 DDX54	2.88e-03	37	144	3	PS51195
Domain	RNA_helicase_DEAD_Q_motif	DDX3X DDX46 DDX54	2.88e-03	37	144	3	IPR014014
Domain	Grip	RGPD8 RGPD5	3.10e-03	11	144	2	SM00755
Domain	GRIP	RGPD8 RGPD5	3.10e-03	11	144	2	PF01465
Domain	DEAH_ATP_HELICASE	SMARCA5 DHX8 SMARCA1	3.11e-03	38	144	3	PS00690
Domain	calpain_III	CAPN14 CAPN6	3.70e-03	12	144	2	SM00720
Domain	C2_III	CAPN14 CAPN6	3.70e-03	12	144	2	IPR033883
Domain	GRIP_dom	RGPD8 RGPD5	3.70e-03	12	144	2	IPR000237
Domain	GRIP	RGPD8 RGPD5	3.70e-03	12	144	2	PS50913
Domain	Calpain_III	CAPN14 CAPN6	3.70e-03	12	144	2	IPR022683
Domain	PP2Ac	PPP1CA PPP1CC	4.36e-03	13	144	2	SM00156
Domain	Calpain_III	CAPN14 CAPN6	4.36e-03	13	144	2	PF01067
Domain	Calpain_domain_III	CAPN14 CAPN6	4.36e-03	13	144	2	IPR022682
Domain	Ser/Thr-sp_prot-phosphatase	PPP1CA PPP1CC	4.36e-03	13	144	2	IPR006186
Domain	SER_THR_PHOSPHATASE	PPP1CA PPP1CC	4.36e-03	13	144	2	PS00125
Domain	Dynein_heavy_chain_D4_dom	DNAH7 DNAH12	5.06e-03	14	144	2	IPR024317
Domain	Myotubularin-like_Pase_dom	MTMR1 MTMR10	5.06e-03	14	144	2	IPR010569
Domain	Dynein_heavy_dom-2	DNAH7 DNAH12	5.06e-03	14	144	2	IPR013602
Domain	DHC_N2	DNAH7 DNAH12	5.06e-03	14	144	2	PF08393
Domain	Calpain_cysteine_protease	CAPN14 CAPN6	5.06e-03	14	144	2	IPR022684
Domain	AAA_8	DNAH7 DNAH12	5.06e-03	14	144	2	PF12780
Domain	PPASE_MYOTUBULARIN	MTMR1 MTMR10	5.06e-03	14	144	2	PS51339
Domain	Myotubularin_fam	MTMR1 MTMR10	5.06e-03	14	144	2	IPR030564
Domain	Myotub-related	MTMR1 MTMR10	5.06e-03	14	144	2	PF06602
Domain	AAA	ABCA4 RNF213 AK9 DNAH7 DNAH12	5.19e-03	144	144	5	SM00382
Domain	AAA+_ATPase	ABCA4 RNF213 AK9 DNAH7 DNAH12	5.19e-03	144	144	5	IPR003593
Domain	-	RANBP2 NAA15 RGPD8 P4HA1 CTR9 LRP2BP	5.42e-03	207	144	6	1.25.40.10
Domain	DHC_fam	DNAH7 DNAH12	5.80e-03	15	144	2	IPR026983
Domain	Peptidase_C2	CAPN14 CAPN6	5.80e-03	15	144	2	PF00648
Domain	Dynein_heavy	DNAH7 DNAH12	5.80e-03	15	144	2	PF03028
Domain	CysPc	CAPN14 CAPN6	5.80e-03	15	144	2	SM00230
Domain	Peptidase_C2_calpain_cat	CAPN14 CAPN6	5.80e-03	15	144	2	IPR001300
Domain	Dynein_heavy_dom	DNAH7 DNAH12	5.80e-03	15	144	2	IPR004273
Domain	CALPAIN_CAT	CAPN14 CAPN6	5.80e-03	15	144	2	PS50203
Domain	PH_dom-like	RANBP2 RGPD8 MYO7A MTMR1 MTMR10 FARP2 DGKK IQSEC1 RGPD5	5.84e-03	426	144	9	IPR011993
Domain	SANT	SMARCA5 SMARCA1 RERE	6.75e-03	50	144	3	SM00717
Domain	SANT/Myb	SMARCA5 SMARCA1 RERE	7.53e-03	52	144	3	IPR001005
Pubmed	FBXO22 promotes leukemogenesis by targeting BACH1 in MLL-rearranged acute myeloid leukemia.	NRIP1 SMARCA5 MYO7A GRB2 RECQL AK9 MON1A PPIB PPP1CA DDX46 DNAH12 P4HA1 DDX54 MEPCE KMT2A MYOM2	5.10e-10	497	149	16	36774506
Pubmed	Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.	RANBP2 SMARCA5 ITCH NAA15 WASHC4 SPOUT1 GPX8 WDR46 RECQL PPIB PPP1CA PPP1CC BLVRA USP5 AP3S1 DST CTR9 GLS DDX54 SMARCA1 IQSEC1 WDR82 DDX60L UQCRC1	3.65e-09	1353	149	24	29467282
Pubmed	BAP1 regulation of the key adaptor protein NCoR1 is critical for γ-globin gene repression.	NRIP1 RANBP2 SMARCA5 HYOU1 SAP18 WDR46 RECQL PPIB DDX3X PPP1CA BLVRA DDX46 AP3S1 P4HA1 CTR9 IFRD2 DDX54 MEPCE IQSEC1 KMT2A WDR82 NAA40 NKTR	1.09e-08	1318	149	23	30463901
Pubmed	Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.	RANBP2 SMARCA5 NAA15 HYOU1 WDR46 RECQL DHX8 PPP1CA PPP1CC USP5 DDX46 DST DDX54 KMT2A UQCRC1 STAG2	2.42e-08	653	149	16	22586326
Pubmed	In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.	RANBP2 SMARCA5 HYOU1 RGPD8 DTNA EML6 REL PPIB PPP1CA PPP1CC ARRB1 DST SACS RRP36 CTR9 SLC27A1 DGKK GLS SMARCA1 KMT2A MYOM2 STAG2 RGPD5	5.61e-08	1442	149	23	35575683
Pubmed	Identification of a novel Ran binding protein 2 related gene (RANBP2L1) and detection of a gene cluster on human chromosome 2q11-q12.	RANBP2 RGPD8 RGPD5	3.07e-07	4	149	3	9480752
Pubmed	Transcriptome analysis of mouse stem cells and early embryos.	ITCH SPOUT1 CAPN6 PRXL2A MTMR10 DST GPN2 ARID5B WDR82 DCAF4 STAG2	5.26e-07	363	149	11	14691545
Pubmed	Receptor-mediated clustering of FIP200 bypasses the role of LC3 lipidation in autophagy.	SMARCA5 NAA15 WASHC4 SPOUT1 SAP18 GRB2 DST BRF1 RRP36 DDX54 UHRF1 WDR82	6.71e-07	454	149	12	33226137
Pubmed	A protein-interaction network of interferon-stimulated genes extends the innate immune system landscape.	RANBP2 HYOU1 CORO2A GPX8 DDX60 GRB2 RNF213 RECQL PPP1CA PPP1CC BLVRA USP5 DDX46 AP3S1 DST COQ8A DDX54 KMT2A DDX60L UQCRC1 STAG2	9.63e-07	1440	149	21	30833792
Pubmed	MECP2 directly interacts with RNA polymerase II to modulate transcription in human neurons.	EPHX1 RANBP2 SMARCA5 SAP18 MTMR1 PPIB DDX3X DHX8 PPP1CA PPP1CC DDX46 DST FBXO3 SACS P4HA1 IQSEC1 WDR82 NAA40	9.82e-07	1082	149	18	38697112
Pubmed	SETD1A Methyltransferase Is Physically and Functionally Linked to the DNA Damage Repair Protein RAD18.	SMARCA5 SAP18 PPP1CA CTR9 DDX54 SMARCA1 UHRF1 KMT2A WDR82	1.49e-06	251	149	9	31076518
Pubmed	UBE2S interacting with TRIM21 mediates the K11-linked ubiquitination of LPP to promote the lymphatic metastasis of bladder cancer.	RANBP2 ITCH NAA15 RNF213	1.83e-06	21	149	4	37422473
Pubmed	Targeting USP10 induces degradation of oncogenic ANLN in esophageal squamous cell carcinoma.	SMARCA5 ITCH NAA15 HYOU1 SPOUT1 CORO2A SAP18 DDX60 RECQL PPIB DDX3X DHX8 PPP1CA PPP1CC DST GLS DDX54 MEPCE SMARCA1	1.98e-06	1257	149	19	36526897
Pubmed	In vitro nuclear interactome of the HIV-1 Tat protein.	RANBP2 SMARCA5 SAP18 RNF213 DDX3X PPP1CC DDX46 KMT2A	2.14e-06	195	149	8	19454010
Pubmed	KAP1 facilitates reinstatement of heterochromatin after DNA replication.	RANBP2 SMARCA5 WASHC4 WDR46 RECQL DDX3X DHX8 PPP1CC BLVRA MRPS30 AP3S1 SMARCA1 WDR82 UQCRC1	2.25e-06	704	149	14	29955894
Pubmed	Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.	RANBP2 HYOU1 DTNA GRB2 MTMR1 RNF213 NUDCD3 PTEN PPIB MTMR10 PPP1CA PPP1CC FBXO3 P4HA1 CTR9 DDX54 WDR82	2.85e-06	1049	149	17	27880917
Pubmed	H4K20me0 recognition by BRCA1-BARD1 directs homologous recombination to sister chromatids.	RANBP2 SMARCA5 SAP18 DDX3X DHX8 PPP1CA PPP1CC DDX46 DST CTR9 ARID5B DDX54 UHRF1 KMT2A WDR82 NAA40 NKTR TAF1L STAG2	3.01e-06	1294	149	19	30804502
Pubmed	Mapping a dynamic innate immunity protein interaction network regulating type I interferon production.	ITCH HYOU1 GRB2 PPP1CC GTPBP2 COQ8A P4HA1 IFRD2 IQSEC1	3.98e-06	283	149	9	21903422
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	ITCH NAA15 N4BP3 CBL DNAH7 DDX3X PPP1CA FSIP2 STOX2 DST MEPCE IQSEC1 KMT2A PRKCG CCSER1	4.81e-06	861	149	15	36931259
Pubmed	Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.	ERCC4 NAA15 HYOU1 ENPP1 PARG DDX3X ALG10B FARP2 GTPBP2 DST COQ8A CTR9 KMT2A	4.94e-06	650	149	13	38777146
Pubmed	Prediction of the coding sequences of unidentified human genes. XI. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.	SNX13 FARP2 DDX46 DST SACS IQSEC1	5.07e-06	101	149	6	9872452
Pubmed	TRIM33 drives prostate tumor growth by stabilizing androgen receptor from Skp2-mediated degradation.	SMARCA5 ESD RECQL USP5 DDX46 ARID5B ZFHX3 RERE	5.23e-06	220	149	8	35785414
Pubmed	NuRD subunit CHD4 regulates super-enhancer accessibility in rhabdomyosarcoma and represents a general tumor dependency.	SMARCA5 SAP18 DHX8 SMARCA1 KMT2A ZFHX3	5.68e-06	103	149	6	32744500
Pubmed	ZZW-115-dependent inhibition of NUPR1 nuclear translocation sensitizes cancer cells to genotoxic agents.	RANBP2 SMARCA5 SAP18 RECQL PPIB DDX3X PPP1CA PPP1CC DDX46 DST CTR9 SMARCA1 UHRF1	5.82e-06	660	149	13	32780723
Pubmed	Synthetic Lethal and Resistance Interactions with BET Bromodomain Inhibitors in Triple-Negative Breast Cancer.	RANBP2 SMARCA5 SAP18 ESD RNF213 RECQL PPP1CA BLVRA USP5 DDX46 CTR9 MEPCE UHRF1 KMT2A WDR82 STAG2	7.94e-06	1014	149	16	32416067
Pubmed	Multiplexed kinase interactome profiling quantifies cellular network activity and plasticity.	WASHC4 DTNA GRB2 CBL DENND11 PPP1CA PPP1CC DST CTR9 KMT2A WDR82 NKTR DDX60L SH2D1A TAF1L	9.28e-06	910	149	15	36736316
Pubmed	Systematic analysis of human protein complexes identifies chromosome segregation proteins.	RANBP2 NAA15 WASHC4 RGPD8 PPIB PPP1CA PPP1CC TUBGCP6 STOX2 DDX46 ARRB1 WDR82 DIXDC1 DCAF4 STAG2 TBCD RGPD5	1.01e-05	1155	149	17	20360068
Pubmed	KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.	HYOU1 MYO7A CORO2A GRB2 MTMR1 PPIB PPP1CA PPP1CC USP5 DST SACS SLC27A1 IQSEC1 KMT2A PACS2 PRKCG MCAT UQCRC1 WNK2	1.25e-05	1431	149	19	37142655
Pubmed	Interactions of the Antiviral Factor Interferon Gamma-Inducible Protein 16 (IFI16) Mediate Immune Signaling and Herpes Simplex Virus-1 Immunosuppression.	SMARCA5 RGPD8 SAP18 WDR46 RNF213 DHX8 DDX54 SMARCA1 DDX60L	1.43e-05	332	149	9	25693804
Pubmed	A Global Analysis of the Receptor Tyrosine Kinase-Protein Phosphatase Interactome.	EML6 GRB2 MTMR1 PTEN PPIB DNAH7 MTMR10 PPP1CA PPP1CC DIXDC1	1.46e-05	420	149	10	28065597
Pubmed	Polymorphism of human Alpha class glutathione transferases.	GSTA1 GSTA2	1.82e-05	2	149	2	11668220
Pubmed	Human liver glutathione S-transferases: complete primary sequence of an Ha subunit cDNA.	GSTA1 GSTA2	1.82e-05	2	149	2	3800996
Pubmed	Interaction between the nicotinic acetylcholine receptor and Grb2. Implications for signaling at the neuromuscular junction.	GRB2 CHRND	1.82e-05	2	149	2	9668219
Pubmed	Mutations in myosin VIIA (MYO7A) and usherin (USH2A) in Spanish patients with Usher syndrome types I and II, respectively.	MYO7A USH2A	1.82e-05	2	149	2	12112664
Pubmed	Nucleotide sequence of the human liver glutathione S-transferase subunit 1 cDNA.	GSTA1 GSTA2	1.82e-05	2	149	2	3678589
Pubmed	Regulation of the association of p120cbl with Grb2 in Jurkat T cells.	GRB2 CBL	1.82e-05	2	149	2	8824292
Pubmed	grb2 heterozygosity rescues embryonic lethality but not tumorigenesis in pten+/- mice.	GRB2 PTEN	1.82e-05	2	149	2	15492213
Pubmed	A TNF- and c-Cbl-dependent FLIP(S)-degradation pathway and its function in Mycobacterium tuberculosis-induced macrophage apoptosis.	CBL MAP3K5	1.82e-05	2	149	2	19597496
Pubmed	The basic glutathione S-transferases from human livers are products of separate genes.	GSTA1 GSTA2	1.82e-05	2	149	2	3036131
Pubmed	The extended catalysis of glutathione transferase.	GSTA1 GSTA2	1.82e-05	2	149	2	21163259
Pubmed	Human glutathione S-transferase A2 polymorphisms: variant expression, distribution in prostate cancer cases/controls and a novel form.	GSTA1 GSTA2	1.82e-05	2	149	2	15128049
Pubmed	Effect of polymorphism in the human glutathione S-transferase A1 promoter on hepatic GSTA1 and GSTA2 expression.	GSTA1 GSTA2	1.82e-05	2	149	2	11692074
Pubmed	Additive Effect of Zfhx3/Atbf1 and Pten Deletion on Mouse Prostatic Tumorigenesis.	PTEN ZFHX3	1.82e-05	2	149	2	26233892
Pubmed	Inactivation of PTEN and ZFHX3 in Mammary Epithelial Cells Alters Patterns of Collective Cell Migration.	PTEN ZFHX3	1.82e-05	2	149	2	36613756
Pubmed	Leucine zipper-mediated homodimerization of the adaptor protein c-Cbl. A role in c-Cbl's tyrosine phosphorylation and its association with epidermal growth factor receptor.	GRB2 CBL	1.82e-05	2	149	2	10521482
Pubmed	Spermiogenesis is impaired in mice bearing a targeted mutation in the protein phosphatase 1cgamma gene.	PPP1CA PPP1CC	1.82e-05	2	149	2	9882500
Pubmed	Evidence that glutathione S-transferases B1B1 and B2B2 are the products of separate genes and that their expression in human liver is subject to inter-individual variation. Molecular relationships between the B1 and B2 subunits and other Alpha class glutathione S-transferases.	GSTA1 GSTA2	1.82e-05	2	149	2	2604726
Pubmed	Isolation of a cDNA clone and localization of human glutathione S-transferase 2 genes to chromosome band 6p12.	GSTA1 GSTA2	1.82e-05	2	149	2	3031680
Pubmed	A possible 5'-NRIP1/UHRF1-3' fusion gene detected by array CGH analysis in a Ph+ ALL patient.	NRIP1 UHRF1	1.82e-05	2	149	2	22285022
Pubmed	MYO7A and USH2A gene sequence variants in Italian patients with Usher syndrome.	MYO7A USH2A	1.82e-05	2	149	2	25558175
Pubmed	The Study of a 231 French Patient Cohort Significantly Extends the Mutational Spectrum of the Two Major Usher Genes MYO7A and USH2A.	MYO7A USH2A	1.82e-05	2	149	2	34948090
Pubmed	CBL mutations in infant acute lymphoblastic leukaemia.	CBL KMT2A	1.82e-05	2	149	2	21988239
Pubmed	Epidermal growth factor receptor internalization through clathrin-coated pits requires Cbl RING finger and proline-rich domains but not receptor polyubiquitylation.	GRB2 CBL	1.82e-05	2	149	2	12839496
Pubmed	Genetic variation and haplotype structures of the glutathione S-transferase genes GSTA1 and GSTA2 in Japanese colorectal cancer patients.	GSTA1 GSTA2	1.82e-05	2	149	2	21844655
Pubmed	PP-1α and PP-1γ display antagonism and differential roles in tumorigenicity of lung cancer cells.	PPP1CA PPP1CC	1.82e-05	2	149	2	23176181
Pubmed	Identification of CBL, a proto-oncogene at 11q23.3, as a novel MLL fusion partner in a patient with de novo acute myeloid leukemia.	CBL KMT2A	1.82e-05	2	149	2	12696071
Pubmed	Human glutathione S-transferases. The Ha multigene family encodes products of different but overlapping substrate specificities.	GSTA1 GSTA2	1.82e-05	2	149	2	3138230
Pubmed	Characterisation of microvascular abnormalities using OCT angiography in patients with biallelic variants in USH2A and MYO7A.	MYO7A USH2A	1.82e-05	2	149	2	31266775
Pubmed	Heterologous expression of recombinant human glutathione transferase A1-1 from a hepatoma cell line.	GSTA1 GSTA2	1.82e-05	2	149	2	1330133
Pubmed	CLINICAL PRESENTATION AND DISEASE COURSE OF USHER SYNDROME BECAUSE OF MUTATIONS IN MYO7A OR USH2A.	MYO7A USH2A	1.82e-05	2	149	2	27828912
Pubmed	Coupling of the c-Cbl protooncogene product to ErbB-1/EGF-receptor but not to other ErbB proteins.	GRB2 CBL	1.82e-05	2	149	2	8649804
Pubmed	The role of GSTA2 polymorphisms and haplotypes in breast cancer susceptibility: a case-control study in the Portuguese population.	GSTA1 GSTA2	1.82e-05	2	149	2	19639209
Pubmed	Novel mutations in MYO7A and USH2A in Usher syndrome.	MYO7A USH2A	1.82e-05	2	149	2	15823922
Pubmed	Characterization of two novel subunits of the alpha-class glutathione S-transferases of human liver.	GSTA1 GSTA2	1.82e-05	2	149	2	8431482
Pubmed	Melatonin safeguards against fatty liver by antagonizing TRAFs-mediated ASK1 deubiquitination and stabilization in a β-arrestin-1 dependent manner.	MAP3K5 ARRB1	1.82e-05	2	149	2	31541591
Pubmed	Global mapping of herpesvirus-host protein complexes reveals a transcription strategy for late genes.	GPX8 PRXL2A GRB2 RECQL PPP1CA PPP1CC CTR9 SMARCA1 MCAT UQCRC1 TBCD	2.04e-05	533	149	11	25544563
Pubmed	Host E3 ligase HUWE1 attenuates the proapoptotic activity of the MERS-CoV accessory protein ORF3 by promoting its ubiquitin-dependent degradation.	EPHX1 RANBP2 NAA15 HYOU1 ESD RECQL PPIB DDX3X USP5 WDR82 MCAT	2.07e-05	534	149	11	35032548
Pubmed	The Hsp70-Hsp90 co-chaperone Hop/Stip1 shifts the proteostatic balance from folding towards degradation.	RANBP2 SMARCA5 NAA15 HYOU1 IFT172 DDX3X PPP1CC USP5 DDX46 COQ8A CTR9 STAG2	2.12e-05	638	149	12	33239621
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	NRIP1 ITCH SPATA6 DTNA RNF213 NUDCD3 PTEN FARP2 ARRB1 COQ8A RRP36 ARID5B ZFHX3 ANKRD12 UQCRC1 RERE STAG2 WNK2 TBCD	2.17e-05	1489	149	19	28611215
Pubmed	Interaction network of human early embryonic transcription factors.	RANBP2 SMARCA5 HYOU1 ARID5B SMARCA1 UHRF1 KMT2A ZFHX3 RERE	2.22e-05	351	149	9	38297188
Pubmed	The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.	RANBP2 N4BP3 DHX8 PPP1CC FARP2 SLC9A1 DDX46 ARRB1 DST P4HA1 CTR9 IFRD2 KMT2A WDR82 ZFHX3 MCAT UQCRC1 TAF1L STAG2	2.34e-05	1497	149	19	31527615
Pubmed	Proteome-wide identification of HSP70/HSC70 chaperone clients in human cells.	EPHX1 RANBP2 SMARCA5 ITCH NAA15 HYOU1 RNF213 RECQL NUDCD3 PPIB DDX3X BLVRA USP5 DDX46 AP3S1 P4HA1 ANO6 TBCD	2.41e-05	1367	149	18	32687490
Pubmed	Complementary proteomics strategies capture an ataxin-1 interactome in Neuro-2a cells.	RANBP2 SMARCA5 HYOU1 RGPD8 DDX3X PPP1CC DDX46 P4HA1 CTR9 SMARCA1 UQCRC1 TBCD	3.18e-05	665	149	12	30457570
Pubmed	Structural and biochemical characterization of the human cyclophilin family of peptidyl-prolyl isomerases.	RANBP2 PPIB NKTR	3.38e-05	15	149	3	20676357
Pubmed	Identification of Novel Proteins Co-Purifying with Cockayne Syndrome Group B (CSB) Reveals Potential Roles for CSB in RNA Metabolism and Chromatin Dynamics.	SMARCA5 DDX3X CTR9 SMARCA1	3.51e-05	43	149	4	26030138
Pubmed	Impact of WIN site inhibitor on the WDR5 interactome.	MTMR1 IQSEC1 KMT2A RERE	3.51e-05	43	149	4	33472061
Pubmed	Identifying biological pathways that underlie primordial short stature using network analysis.	RANBP2 SMARCA5 HYOU1 WDR46 PPIB DDX3X DHX8 PPP1CA DDX46 DST SACS RRP36 DDX54 UHRF1 STAG2	3.64e-05	1024	149	15	24711643
Pubmed	Assembly of the U5 snRNP component PRPF8 is controlled by the HSP90/R2TP chaperones.	RANBP2 SMARCA5 NAA15 HYOU1 GRB2 RECQL PPIB DDX3X DHX8 PPP1CA USP5 DDX46 ARRB1 AP3S1 FBXO3 CTR9 DDX54 STAG2	3.78e-05	1415	149	18	28515276
Pubmed	Protein Phosphatase 1 Subunit PPP1R14B Stabilizes STMN1 to Promote Progression and Paclitaxel Resistance in Triple-Negative Breast Cancer.	PPP1CA PPP1CC USP5	4.14e-05	16	149	3	36484700
Pubmed	A Single Adaptable Cochaperone-Scaffold Complex Delivers Nascent Iron-Sulfur Clusters to Mammalian Respiratory Chain Complexes I-III.	RANBP2 GPX8 PRXL2A DDX3X FARP2 BLVRA MRPS30 USP5 FBXO3 P4HA1 GLS ARID5B	4.28e-05	686	149	12	28380382
Pubmed	Defining the membrane proteome of NK cells.	RANBP2 ITCH NAA15 HYOU1 RNF213 RECQL TTPAL PPIB TUBGCP6 P4HA1 ANO6 SLC27A1 DDX54 IQSEC1 STAG2 CTSW	4.42e-05	1168	149	16	19946888
Pubmed	Hereditary Ataxia Overview	SLC9A1 COQ8A SACS PRKCG ZFHX3	4.92e-05	92	149	5	20301317
Pubmed	ATG5 is required for B cell polarization and presentation of particulate antigens.	RANBP2 SMARCA5 RGPD8 CORO2A GRB2 PPP1CA PPP1CC USP5 AP3S1 DDX54 MEPCE NKTR	5.27e-05	701	149	12	30196744
Pubmed	Mapping of unconventional myosins in mouse and human.	MYO7A GSTA1 GSTA2 GLS	5.44e-05	48	149	4	8884266
Pubmed	Regulation of immune responses by E3 ubiquitin-protein ligases.	ITCH CBL	5.45e-05	3	149	2	11826757
Pubmed	The proto-oncogene product c-Cbl becomes tyrosine phosphorylated by stimulation with GM-CSF or Epo and constitutively binds to the SH3 domain of Grb2/Ash in human hematopoietic cells.	GRB2 CBL	5.45e-05	3	149	2	7537740
Pubmed	Searching the second hit in patients with inherited retinal dystrophies and monoallelic variants in ABCA4, USH2A and CEP290 by whole-gene targeted sequencing.	ABCA4 USH2A	5.45e-05	3	149	2	30190494
Pubmed	The Genetics of Usher Syndrome in the Israeli and Palestinian Populations.	MYO7A USH2A	5.45e-05	3	149	2	29490346
Pubmed	Interactions of Cbl with Grb2 and phosphatidylinositol 3'-kinase in activated Jurkat cells.	GRB2 CBL	5.45e-05	3	149	2	7791764
Pubmed	p120c-cbl is present in human blood platelets and is differentially involved in signaling by thrombopoietin and thrombin.	GRB2 CBL	5.45e-05	3	149	2	8695851
Pubmed	Mutually exclusive binding of PP1 and RNA to AKAP149 affects the mitochondrial network.	PPP1CA PPP1CC	5.45e-05	3	149	2	19074462
Pubmed	Association of DJ-1/PTEN/AKT- and ASK1/p38-mediated cell signalling with ischaemic cardiomyopathy.	PTEN MAP3K5	5.45e-05	3	149	2	23015639
Pubmed	Growth factor receptor binding protein 2-mediated recruitment of the RING domain of Cbl to the epidermal growth factor receptor is essential and sufficient to support receptor endocytosis.	GRB2 CBL	5.45e-05	3	149	2	15635092
Pubmed	1E7-03, a low MW compound targeting host protein phosphatase-1, inhibits HIV-1 transcription.	PPP1CA PPP1CC	5.45e-05	3	149	2	25073485
Pubmed	Long noncoding RNA PM maintains cerebellar synaptic integrity and Cbln1 activation via Pax6/Mll1-mediated H3K4me3.	CBLN1 KMT2A	5.45e-05	3	149	2	34111112
Pubmed	Arresting a transient receptor potential (TRP) channel: beta-arrestin 1 mediates ubiquitination and functional down-regulation of TRPV4.	ITCH ARRB1	5.45e-05	3	149	2	20650893
Pubmed	The direct binding of the catalytic subunit of protein phosphatase 1 to the PKR protein kinase is necessary but not sufficient for inactivation and disruption of enzyme dimer formation.	PPP1CA PPP1CC	5.45e-05	3	149	2	12138106
Pubmed	Chromosomal localization of human, rat, and mouse protein phosphatase type 1 beta catalytic subunit genes (PPP1CB) by fluorescence in situ hybridization.	PPP1CA PPP1CC	5.45e-05	3	149	2	7857673
Pubmed	Nedd4-1 and beta-arrestin-1 are key regulators of Na+/H+ exchanger 1 ubiquitylation, endocytosis, and function.	SLC9A1 ARRB1	5.45e-05	3	149	2	20855896
Pubmed	Epidermal growth factor receptor exposed to cigarette smoke is aberrantly activated and undergoes perinuclear trafficking.	GRB2 CBL	5.45e-05	3	149	2	17971399
Interaction	CIT interactions	NRIP1 RANBP2 AMPD3 SMARCA5 SPOUT1 SAP18 DDX60 RNF213 RECQL PTEN PPIB MAP3K5 DHX8 PPP1CA PPP1CC DDX46 DNAH12 FBXO3 P4HA1 CTR9 MEPCE SMARCA1 UHRF1 KMT2A NAA40 NKTR MYOM2 DDX60L UQCRC1 STAG2 CCSER1	2.84e-08	1450	144	31	int:CIT
Interaction	FLNA interactions	RANBP2 HYOU1 CORO2A CAPN6 GRB2 REL PTEN CBL PPIB DHX8 PPP1CA PPP1CC ARRB1 MEPCE WDR82 DIXDC1 NAA40 DCAF4 STAG2	1.90e-07	648	144	19	int:FLNA
Interaction	FBXO22 interactions	NRIP1 SMARCA5 MYO7A GRB2 RECQL AK9 MON1A PTEN PPIB PPP1CA DDX46 DNAH12 P4HA1 DDX54 MEPCE KMT2A MYOM2	3.29e-07	540	144	17	int:FBXO22
Interaction	LTK interactions	HYOU1 SAP18 GRB2 NUDCD3 CBL BLVRA MRPS30 DST DDX54	1.49e-06	152	144	9	int:LTK
Interaction	AR interactions	NRIP1 SMARCA5 SAP18 ESD GRB2 RNF213 RECQL REL PTEN DDX3X PPP1CA USP5 DDX46 CTR9 ARID5B MEPCE UHRF1 KMT2A ZFHX3 RERE SH2D1A IL23R	2.18e-06	992	144	22	int:AR
Interaction	FLT3 interactions	SMARCA5 HYOU1 GRB2 RNF213 CBL COQ8A P4HA1 GLS DDX54 KMT2A TAF1L	1.84e-05	318	144	11	int:FLT3
Interaction	RIT1 interactions	RANBP2 NAA15 RGPD8 SPOUT1 SAP18 WDR46 GRB2 DDX3X DHX8 MRPS30 DDX46 BRF1 CTR9 GPN2 GLS DDX54 MEPCE UHRF1 WDR82 NKTR MCAT UQCRC1 TBCD	2.06e-05	1230	144	23	int:RIT1
Interaction	CPSF6 interactions	ITCH SAP18 GRB2 RECQL DDX3X DHX8 PPP1CA PPP1CC P4HA1 CTR9 MEPCE WDR82 NAA40 NKTR	2.53e-05	526	144	14	int:CPSF6
Interaction	FLT1 interactions	SMARCA5 HYOU1 GRB2 RNF213 CBL COQ8A P4HA1 DDX54	4.46e-05	179	144	8	int:FLT1
Interaction	DBN1 interactions	CORO2A GRB2 PTEN PPP1CA PPP1CC DST BRF1 MEPCE UHRF1 DIXDC1 NAA40 STAG2	4.66e-05	417	144	12	int:DBN1
Interaction	CSNK2A1 interactions	NRIP1 ITCH NAA15 WASHC4 MTMR1 REL PTEN DDX3X PPP1CA ARRB1 DST BRF1 P4HA1 CTR9 DDX54 MEPCE KMT2A WDR82 NKTR	5.20e-05	956	144	19	int:CSNK2A1
Interaction	ZMYND11 interactions	SMARCA5 SAP18 PPIB MEPCE KMT2A WDR82	5.82e-05	94	144	6	int:ZMYND11
Interaction	UBE2S interactions	RANBP2 ITCH NAA15 RNF213 PTEN USP5 MEPCE	6.10e-05	138	144	7	int:UBE2S
Interaction	EPHB1 interactions	GRB2 PTEN CBL PRKCG	6.77e-05	31	144	4	int:EPHB1
Interaction	ACTA1 interactions	MYO7A DTNA GRB2 MTMR1 CBL PPP1CA USP5 ARRB1 DST MEPCE NAA40	7.47e-05	371	144	11	int:ACTA1
Interaction	AATK interactions	SMARCA5 WASHC4 HYOU1 PTEN MTMR10 PPP1CA PPP1CC P4HA1	7.86e-05	194	144	8	int:AATK
Interaction	DPY30 interactions	SMARCA5 PPP1CC ARRB1 AP3S1 SMARCA1 KMT2A WDR82 RERE	1.12e-04	204	144	8	int:DPY30
Interaction	MECP2 interactions	EPHX1 RANBP2 SMARCA5 SPOUT1 SAP18 MTMR1 PPIB DDX3X DHX8 PPP1CA PPP1CC DDX46 DST FBXO3 SACS P4HA1 DDX54 MEPCE IQSEC1 WDR82 NAA40 NKTR	1.20e-04	1287	144	22	int:MECP2
Interaction	PPP1R2B interactions	PPP1CA PPP1CC NAA40	1.23e-04	14	144	3	int:PPP1R2B
Interaction	CALD1 interactions	SAP18 GRB2 PTEN PPP1CA PPP1CC ARRB1 DST KMT2A NAA40	1.25e-04	265	144	9	int:CALD1
Interaction	SON interactions	SAP18 PTEN DDX3X DHX8 PPP1CA PPP1CC NAA40 NKTR	1.28e-04	208	144	8	int:SON
Interaction	CHRND interactions	EPHX1 GPX8 PRXL2A GRB2 CHRND	1.45e-04	70	144	5	int:CHRND
Interaction	NR2C2 interactions	NRIP1 RANBP2 SMARCA5 HYOU1 SAP18 WDR46 RECQL PPIB DDX3X PPP1CA BLVRA DDX46 AP3S1 P4HA1 CTR9 IFRD2 DDX54 MEPCE IQSEC1 KMT2A WDR82 NAA40 NKTR	1.53e-04	1403	144	23	int:NR2C2
Cytoband	6p12.1	GSTA1 GSTA2 DST	1.67e-04	33	148	3	6p12.1
Cytoband	Xq25	SMARCA1 SH2D1A STAG2	3.20e-04	41	148	3	Xq25
GeneFamily	DEAD-box helicases	DDX60 DDX3X DDX46 DDX54	9.06e-05	42	102	4	499
GeneFamily	Cyclophilin peptidylprolyl isomerases	RANBP2 PPIB NKTR	1.58e-04	19	102	3	909
GeneFamily	N(alpha)-acetyltransferase subunits\|GCN5 related N-acetyltransferases	NAA15 NAA40	2.00e-03	12	102	2	660
GeneFamily	Protein phosphatase catalytic subunits\|EF-hand domain containing	PPP1CA PPP1CC	2.36e-03	13	102	2	693
GeneFamily	C2 domain containing\|Calpains	CAPN14 CAPN6	3.15e-03	15	102	2	975
GeneFamily	Myotubularins\|Phosphoinositide phosphatases	MTMR1 MTMR10	3.15e-03	15	102	2	903
GeneFamily	GATA zinc finger domain containing\|Myb/SANT domain containing	SMARCA5 SMARCA1 RERE	3.33e-03	53	102	3	532
GeneFamily	WD repeat domain containing	CORO2A IFT172 EML6 WDR46 WDR82 DCAF4	3.69e-03	262	102	6	362
GeneFamily	Dyneins, axonemal	DNAH7 DNAH12	4.06e-03	17	102	2	536
GeneFamily	Tetratricopeptide repeat domain containing\|Bardet-Biedl syndrome associated\|BBSome	RANBP2 RGPD8 CTR9 RGPD5	4.09e-03	115	102	4	769
Coexpression	FLECHNER_BIOPSY_KIDNEY_TRANSPLANT_OK_VS_DONOR_UP	NRIP1 TRIM2 WASHC4 SAP18 PARG RECQL PPIB DDX3X AP3S1 DST GLS ARID5B UQCRC1 RERE	3.48e-06	568	145	14	M4023
Coexpression	GSE15750_DAY6_VS_DAY10_EFF_CD8_TCELL_DN	SPOUT1 IFT172 DDX60 RNF213 FARP2 ARRB1 BRF1 RERE	1.63e-05	200	145	8	M3579
Coexpression	GAUSSMANN_MLL_AF4_FUSION_TARGETS_F_DN	AMPD3 GSTA1 GSTA2 MYOM2	4.12e-05	35	145	4	M588
Coexpression	LAKE_ADULT_KIDNEY_C26_MESANGIAL_CELLS	PTEN MAP3K5 DST ARID5B PIP5K1B NKTR ANKRD12	6.00e-05	177	145	7	M39245
Coexpression	HAMAI_APOPTOSIS_VIA_TRAIL_UP	ST6GALNAC1 NRIP1 TRIM2 NAA15 RECQL PTEN SNX13 STOX2 DDX46 SACS ZNF257 NKTR STAG2	7.57e-05	656	145	13	M18979
Coexpression	DACOSTA_UV_RESPONSE_VIA_ERCC3_DN	NRIP1 RANBP2 SMARCA5 ITCH TRIM2 WASHC4 PARG PTEN SNX13 DST SACS ARID5B SMARCA1 ZFHX3 STAG2	8.38e-05	856	145	15	M4500
Coexpression	GAUSSMANN_MLL_AF4_FUSION_TARGETS_F_DN	AMPD3 GSTA1 GSTA2 MYOM2	1.03e-04	44	145	4	MM485
Coexpression	SHEDDEN_LUNG_CANCER_GOOD_SURVIVAL_A4	EPHX1 ABCA4 TRIM2 REL BLVRA ARRB1 GLS	1.17e-04	197	145	7	M12824
Coexpression	GSE29618_PRE_VS_DAY7_FLU_VACCINE_MONOCYTE_UP	ITCH ERCC4 SPATA6 PPIB GTPBP2 IQSEC1 DIXDC1	1.17e-04	197	145	7	M4975
Coexpression	ERBB2_UP.V1_DN	NRIP1 SMARCA5 NAA15 DDX60 RECQL GFRA1 ANKRD12	1.17e-04	197	145	7	M2635
Coexpression	GSE13485_DAY3_VS_DAY7_YF17D_VACCINE_PBMC_DN	NRIP1 DDX60 RNF213 SUCNR1 CHRND BLVRA DDX60L	1.21e-04	198	145	7	M3302
Coexpression	GSE2770_TGFB_AND_IL4_VS_IL4_TREATED_ACT_CD4_TCELL_48H_DN	NRIP1 SPATA6 MYO7A CORO2A COQ8A RERE TBCD	1.21e-04	198	145	7	M6114
Coexpression	GSE15330_GRANULOCYTE_MONOCYTE_PROGENITOR_VS_PRO_BCELL_UP	SAP18 WDR46 N4BP3 CTR9 MYOM2 UQCRC1 TBCD	1.25e-04	199	145	7	M7041
Coexpression	GSE360_L_DONOVANI_VS_T_GONDII_MAC_UP	AMPD3 ABCA4 MYO7A DNAH7 BLVRA KMT2A USH2A	1.25e-04	199	145	7	M5233
Coexpression	GSE41867_NAIVE_VS_DAY15_LCMV_EFFECTOR_CD8_TCELL_DN	REL N4BP3 CBL GLS IQSEC1 NKTR STAG2	1.29e-04	200	145	7	M9472
Coexpression	GSE411_WT_VS_SOCS3_KO_MACROPHAGE_IL6_STIM_400MIN_DN	AMPD3 MTMR10 MAP3K5 DDX46 PIP5K1B MCAT GALNT4	1.29e-04	200	145	7	M5984
Coexpression	GSE23984_CTRL_VS_HYPOCALEMIC_VITAMIND_ANALOG_TCELL_DN	WASHC4 CORO2A ENPP1 GRB2 SLC27A1 KMT2A DCAF4	1.29e-04	200	145	7	M8052
Coexpression	GSE9650_NAIVE_VS_EFF_CD8_TCELL_UP	EPHX1 AMPD3 ARRB1 P4HA1 IFRD2 KMT2A RERE	1.29e-04	200	145	7	M5819
Coexpression	GSE32986_CURDLAN_LOWDOSE_VS_GMCSF_AND_CURDLAN_LOWDOSE_STIM_DC_UP	GRB2 MTMR10 BLVRA PACS2 RERE STAG2 GALNT4	1.29e-04	200	145	7	M8625
Coexpression	GSE25123_WT_VS_PPARG_KO_MACROPHAGE_ROSIGLITAZONE_STIM_UP	EPHX1 NRIP1 GPR82 SNX13 MAP3K5 DST GALNT4	1.29e-04	200	145	7	M7978
Coexpression	GSE11924_TH2_VS_TH17_CD4_TCELL_DN	ERCC4 MON1A DDX46 SLC27A1 UHRF1 PACS2 SH2D1A	1.29e-04	200	145	7	M3165
Coexpression	GSE20366_TREG_VS_NAIVE_CD4_TCELL_DEC205_CONVERSION_UP	RNF144B EPHX1 MRC1 CBL DNAH7 P4HA1 WDR82	1.29e-04	200	145	7	M4332
Coexpression	BHAT_ESR1_TARGETS_NOT_VIA_AKT1_DN	RNF144B ENPP1 MAP3K5 ARID5B RERE	1.31e-04	88	145	5	M2232
CoexpressionAtlas	dev gonad_e13.5_M_InterstitFLeydig_MafB_top-relative-expression-ranked_100	EPHX1 CBLN1 GSTA1 HHIP SMARCA1 ENPEP	9.86e-06	73	143	6	gudmap_dev gonad_e13.5_M_InterstitFLeydig_MafB_100
CoexpressionAtlas	dev gonad_e13.5_M_InterstitTestis_Sma_k-means-cluster#3_top-relative-expression-ranked_100	CBLN1 HHIP STOX2 ENPEP	1.89e-05	24	143	4	gudmap_dev gonad_e13.5_M_InterstitTestis_Sma_k3_100
CoexpressionAtlas	dev gonad_e12.5_M_InterstitTestis_Sma_k-means-cluster#2_top-relative-expression-ranked_200	CBLN1 HHIP STOX2 ENPEP	3.07e-05	27	143	4	gudmap_dev gonad_e12.5_M_InterstitTestis_Sma_k2_200
CoexpressionAtlas	dev gonad_e12.5_M_DevVasTestis_Flk_k-means-cluster#3_top-relative-expression-ranked_500	EPHX1 CBLN1 GSTA1 HHIP	3.56e-05	28	143	4	gudmap_dev gonad_e12.5_M_gudmap_devVasTestis_Flk_k3_500
CoexpressionAtlas	DevelopingGonad_e18.5_testes_emap-11164_k-means-cluster#1_top-relative-expression-ranked_200	DTNA CBLN1 GSTA1 GSTA2 HHIP	3.74e-05	56	143	5	gudmap_developingGonad_e18.5_testes_200_k1
CoexpressionAtlas	dev gonad_e12.5_M_InterstitLeydig_MafB_top-relative-expression-ranked_200	RNF213 CBLN1 GSTA1 HHIP STOX2 SMARCA1 ENPEP	4.21e-05	138	143	7	gudmap_dev gonad_e12.5_M_InterstitLeydig_MafB_200
CoexpressionAtlas	dev gonad_e12.5_M_DevVasTestis_Flk_k-means-cluster#1_top-relative-expression-ranked_1000	EPHX1 CBLN1 GSTA1 HHIP STOX2	5.24e-05	60	143	5	gudmap_dev gonad_e12.5_M_gudmap_devVasTestis_Flk_k1_1000
CoexpressionAtlas	DevelopingGonad_e14.5_ testes_emap-6710_k-means-cluster#5_top-relative-expression-ranked_500	MYO7A DTNA CBLN1 GSTA1 GSTA2 HHIP	5.31e-05	98	143	6	gudmap_developingGonad_e14.5_ testes_500_k5
CoexpressionAtlas	dev gonad_e13.5_M_InterstitFLeydig_MafB_top-relative-expression-ranked_200	EPHX1 CBLN1 GSTA1 HHIP STOX2 SMARCA1 ENPEP	6.03e-05	146	143	7	gudmap_dev gonad_e13.5_M_InterstitFLeydig_MafB_200
CoexpressionAtlas	DevelopingGonad_e16.5_testes_emap-8444_k-means-cluster#5_top-relative-expression-ranked_200	MYO7A DTNA CBLN1 GSTA1 GSTA2	6.14e-05	62	143	5	gudmap_developingGonad_e16.5_testes_200_k5
CoexpressionAtlas	dev gonad_e13.5_M_DevVasTestis_Flk_k-means-cluster#3_top-relative-expression-ranked_200	EPHX1 CBLN1 GSTA1 HHIP	8.78e-05	35	143	4	gudmap_dev gonad_e13.5_M_gudmap_devVasTestis_Flk_k3_200
CoexpressionAtlas	DevelopingGonad_P2_testes_emap-30171_k-means-cluster#1_top-relative-expression-ranked_200	DTNA CBLN1 GSTA2 HHIP	9.83e-05	36	143	4	gudmap_developingGonad_P2_testes_200_k1
CoexpressionAtlas	DevelopingGonad_e12.5_epididymis_emap-29139_top-relative-expression-ranked_1000	NRIP1 SMARCA5 ITCH NAA15 HYOU1 DTNA INSM1 RNF213 PTEN CBL CBLN1 USP5 HHIP STOX2 ARID5B NKTR	1.09e-04	806	143	16	gudmap_developingGonad_e12.5_epididymis_1000
CoexpressionAtlas	DevelopingGonad_e18.5_testes_emap-11164_top-relative-expression-ranked_200	EPHX1 MYO7A DTNA CBLN1 GSTA1 GSTA2 HHIP	1.35e-04	166	143	7	gudmap_developingGonad_e18.5_testes_200
CoexpressionAtlas	dev gonad_e13.5_M_InterstitTestis_Sma_top-relative-expression-ranked_100	CBLN1 GSTA1 HHIP STOX2 ENPEP	1.62e-04	76	143	5	gudmap_dev gonad_e13.5_M_InterstitTestis_Sma_100
CoexpressionAtlas	dev gonad_e12.5_M_InterstitTestis_Sma_top-relative-expression-ranked_100	CBLN1 HHIP STOX2 SMARCA1 ENPEP	1.84e-04	78	143	5	gudmap_dev gonad_e12.5_M_InterstitTestis_Sma_100
CoexpressionAtlas	dev gonad_e13.5_M_DevVasTestis_Flk_k-means-cluster#1_top-relative-expression-ranked_100	EPHX1 CBLN1 GSTA1	2.27e-04	18	143	3	gudmap_dev gonad_e13.5_M_gudmap_devVasTestis_Flk_k1_100
CoexpressionAtlas	DevelopingGonad_e16.5_testes_emap-8444_k-means-cluster#4_top-relative-expression-ranked_500	EPHX1 CBLN1 GSTA1 GSTA2 STOX2	2.75e-04	85	143	5	gudmap_developingGonad_e16.5_testes_500_k4
ToppCell	mild\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	SMARCA5 DDX60 RNF213 REL DDX3X KMT2A NKTR ANKRD12 DDX60L	2.16e-08	200	146	9	12f1685ce8f218433068e090c9d839cd5a1910bf
ToppCell	10x5'-GI_small-bowel-Lymphocytic_T_CD4-T_CD4/CD8\|GI_small-bowel / Manually curated celltypes from each tissue	RANBP2 RNF213 REL DDX3X GLS KMT2A NKTR ANKRD12	2.06e-07	188	146	8	ab9b725d6e0cdab8e9ddda6dee09e14730e9a578
ToppCell	Immune_cells-pro-B\|Immune_cells / Lineage and Cell class	TRIM2 MYO7A PTEN FCRL6 GFRA1 DST ENPEP	1.64e-06	172	146	7	096636f2589fa56d15942aac96641c16fd5fa78d
ToppCell	BALF-PFMC-Severe-critical_progression_d12-22_no-steroids-Epithelial-Epithelial,_Airway-ciliated_cell\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	ST6GALNAC1 EPHX1 SPATA6 IFT172 GSTA1 GSTA2 DNAH12	3.40e-06	192	146	7	03acd4a26b986e34eee608747347791122f1aa52
ToppCell	BALF-PFMC-Severe-critical_progression_d12-22_no-steroids-Epithelial-Epithelial,_Airway-ciliated_cell-Epi-Ciliated\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	ST6GALNAC1 EPHX1 SPATA6 IFT172 GSTA1 GSTA2 DNAH12	3.40e-06	192	146	7	31c6046589e2fbb0486fd044c5b128099d37872f
ToppCell	facs-Marrow-B-cells-3m-Lymphocytic-immature_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	REL TTPAL PTEN DDX54 IQSEC1 PRKCG LRP2BP	3.76e-06	195	146	7	d77423d0ec64b397c6d1eec181c5fc0acaa92d63
ToppCell	COVID-19_Moderate-CD8+_T_activated\|World / disease group, cell group and cell class	DDX60 TRGV11 RNF213 FCRL6 MYOM2 SH2D1A CTSW	3.76e-06	195	146	7	070c5d3bdbd4ea54a579c01c37fb99bcf823982e
ToppCell	facs-Marrow-B-cells-3m-Lymphocytic-immature_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	REL TTPAL PTEN DDX54 IQSEC1 PRKCG LRP2BP	3.76e-06	195	146	7	f5bf4797972185afa76638293166abd536e5472f
ToppCell	Bronchial_Brush-Epithelial\|Bronchial_Brush / Tissue, Lineage and Cell class of Lung Cells from 10X	EPHX1 TRIM2 IFT172 AK9 GSTA1 GSTA2 DNAH12	4.02e-06	197	146	7	272c7f4e582ef57564450540242b0db766b78328
ToppCell	COVID-19_Mild\|World / Disease group, lineage and cell class	DDX60 RNF213 REL DDX3X NKTR ANKRD12 DDX60L	4.02e-06	197	146	7	5c33454b10023decd2f5ccda9229b6512659711e
ToppCell	PBMC-Mild\|PBMC / Location, Disease Group, Cell group, Cell class (2021.03.09)	DDX60 RNF213 REL DDX3X NKTR ANKRD12 DDX60L	4.16e-06	198	146	7	44417089b62056269cac38d3134ff209c05b7007
ToppCell	PBMC-Mild\|PBMC / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	DDX60 RNF213 REL DDX3X NKTR ANKRD12 DDX60L	4.16e-06	198	146	7	28ef3fc4c17dcb765537b75917f7db78baa522db
ToppCell	BAL-Severe-cDC_4\|Severe / Compartment, Disease Groups and Clusters	MRC1 IFT172 PIP5K1B ZFHX3 DCAF4 RGPD5	1.38e-05	158	146	6	73f66689ef59f71b14cb7141ca5951cc47fe57c1
ToppCell	Children_(3_yrs)-Epithelial-lung_goblet_cell-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	ST6GALNAC1 EPHX1 TRIM2 GSTA1 GSTA2 WNK2	1.53e-05	161	146	6	2d63b279d9a5132e1c09b03930bf9039036d24a2
ToppCell	3'_v3-lymph-node_spleen-Lymphocytic_T_CD4-T_CD4/CD8\|lymph-node_spleen / Manually curated celltypes from each tissue	RANBP2 RNF213 GLS NKTR ANKRD12 ENPEP	2.16e-05	171	146	6	2e9a20f8980b78325c52065a9c14ab3656267c05
ToppCell	droplet-Lung-LUNG-30m-Myeloid-Proliferating_Dendritic\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CORO2A GPR82 RECQL DDIAS UHRF1 NAA40	2.30e-05	173	146	6	6c9ecf77d2fb0f89100fdd7e4e88f85598278bc7
ToppCell	Immune_cells-pro-B\|World / Lineage and Cell class	MYO7A PTEN N4BP3 FCRL6 GFRA1 ENPEP	2.38e-05	174	146	6	e173adbf5789dfa20f3cbc668efde5f0992ac219
ToppCell	ASK452-Epithelial-Secretory\|ASK452 / Donor, Lineage and Cell class of Lung cells from Dropseq	TRIM2 ZNF57 MON1A FARP2 DCAF4 WNK2	2.54e-05	176	146	6	dd334c8a8a31dc26b2d558df0ef6bed6dc1a6610
ToppCell	Severe-CD4+_T_activated\|World / Disease group and Cell class	ST6GALNAC1 RNF144B GPX8 RNF213 ARID5B DDX60L	2.70e-05	178	146	6	ef6111238703579a34bd6948bd9d4ca6b7e16063
ToppCell	Children_(3_yrs)-Epithelial-lung_goblet_cell\|Children_(3_yrs) / Lineage, Cell type, age group and donor	ST6GALNAC1 EPHX1 TRIM2 GSTA1 GSTA2 WNK2	3.06e-05	182	146	6	3f1a666fe27dd7529c114539ed5f6b8ca585c875
ToppCell	3'_v3-lymph-node_spleen-Lymphocytic_Invariant-Inducer-like\|lymph-node_spleen / Manually curated celltypes from each tissue	NRIP1 ENPP1 DDX3X DST CTSW IL23R	3.25e-05	184	146	6	d97471a4fe17cba6880ccf1a04cc00c741558124
ToppCell	droplet-Marrow-nan-3m\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SMARCA5 PARG REL DDX3X KMT2A STAG2	3.25e-05	184	146	6	1154a5ad7b8512272b7476f949ddac350910bfb7
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_1\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	RNF144B EML6 DNAH7 MTMR10 STOX2 TMEM132D	3.25e-05	184	146	6	da06ff24ee2b2cf4715fdfce43030b2da9e0aaf8
ToppCell	CV-Healthy-7\|Healthy / Virus stimulation, Condition and Cluster	RGPD8 MTMR1 ALG10B GLS NAA40 MCAT	3.35e-05	185	146	6	1979d189c204f4c2893e3170a514ee7d5523406c
ToppCell	ILEUM-inflamed-(3)_MNP-(3)_moDC\|(3)_MNP / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	MRC1 EML6 GPR82 PTEN DST NKTR	3.56e-05	187	146	6	0099def970fbc828756fbf853eca2ce77b8cd342
ToppCell	RV-04._Ventricular_Cardiomyocyte_I\|World / Chamber and Cluster_Paper	DTNA COQ8A PIP5K1B MYOM2 WNK2 CCSER1	3.56e-05	187	146	6	78cdcf8bc141d3b155c3c8af908431fc419c4d08
ToppCell	renal_medulla_nuclei\|World / Celltypes from Cells and Nuclei per compartment and clinical group	TRIM2 EML6 MTMR10 STOX2 RERE CCSER1	3.78e-05	189	146	6	830d9cd0dd706bce22eb2416f07b2c31c870a05a
ToppCell	RV-06._Ventricular_Cardiomyocyte_II\|RV / Chamber and Cluster_Paper	DTNA DST PIP5K1B MYOM2 WNK2 CCSER1	3.89e-05	190	146	6	fe8e78922c8ae928ef9a80bffd67868d5a87a091
ToppCell	LV-06._Ventricular_Cardiomyocyte_II\|LV / Chamber and Cluster_Paper	DTNA DST PIP5K1B MYOM2 WNK2 CCSER1	4.01e-05	191	146	6	25f3eb34f4e70761e81e84c8a5829f216108cbc6
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	RNF144B EML6 DNAH7 MTMR10 STOX2 TMEM132D	4.01e-05	191	146	6	d0e9afe7b6334dd515d3e68892efdc76347a55e5
ToppCell	facs-Marrow-T-cells-3m-Lymphocytic-immature_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	REL TTPAL PTEN DDX54 IQSEC1 PRKCG	4.13e-05	192	146	6	2de242d81dc085ae734eb7d1f091af9a542e0866
ToppCell	NS-moderate-d_16-33-Lymphoid-Treg\|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	GPR82 NKTR ANKRD12 SH2D1A CTSW IL23R	4.13e-05	192	146	6	48d557071bad80edd3ec6e5ad8dcd97037da9553
ToppCell	10x5'-lymph-node_spleen-Lymphocytic_T_CD4-T_CD4/CD8\|lymph-node_spleen / Manually curated celltypes from each tissue	RANBP2 RNF213 GLS KMT2A NKTR ANKRD12	4.13e-05	192	146	6	47646d7e4990be85072987f92bf18d52f8da752e
ToppCell	facs-Marrow-T-cells-3m-Lymphocytic-immature_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	REL TTPAL PTEN DDX54 IQSEC1 PRKCG	4.13e-05	192	146	6	ba2a683472a8b785dbf666dc6e94356d879486c3
ToppCell	TCGA-Prostate-Primary_Tumor-Prostate_Adenocarcinoma-Acinar_Adenocarcinoma-6\|TCGA-Prostate / Sample_Type by Project: Shred V9	RANBP2 SMARCA5 ALG10B DTWD2 CTR9 STAG2	4.25e-05	193	146	6	abd71b2cf667ef2b1c4d88acd0c1dd19a12ff659
ToppCell	normal_Pleural_Fluid-T/NK_cells-Exhausted_CD8+_T\|normal_Pleural_Fluid / Location, Cell class and cell subclass	RNF213 FCRL6 PPP1CA SH2D1A CTSW TBCD	4.37e-05	194	146	6	68a9e00c9e1a855eeebfc26c038652f3800758db
ToppCell	PBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_B-B_cell-B_c02-MS4A1-CD27\|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)	WASHC4 FARP2 IQSEC1 PIP5K1B RERE CCSER1	4.37e-05	194	146	6	d852aebf7a763b9a776c4570711f0c759f591910
ToppCell	droplet-Bladder-nan-3m-Epithelial-basal_bladder_epithelial_cell_(Krt5+Krt14+)\|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NRIP1 ESD PRXL2A GSTA1 DST COQ8A	4.37e-05	194	146	6	37803f4abf1aa1ad771c9cd293933003d7101e70
ToppCell	control-Lymphoid-Treg\|Lymphoid / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	NRIP1 RNF213 NKTR ANKRD12 SH2D1A IL23R	4.50e-05	195	146	6	66959ae839eb60a573da06bdd227090ebb5bb9ed
ToppCell	facs-Thymus-nan-3m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CBL DDX3X AP3S1 ANO6 UHRF1 SH2D1A	4.50e-05	195	146	6	79114b3c78cc15c413bb58f0673e7215b784a9b6
ToppCell	COVID_non-vent-Lymphocytic-T_cell-CD4+_Memory_T_cell\|COVID_non-vent / Disease condition, Lineage, Cell class and subclass	ST6GALNAC1 DDX60 DST ARID5B KMT2A ANKRD12	4.50e-05	195	146	6	22191d361af136942508f1553ff41a626ed982ad
ToppCell	COVID-19_Severe-Lymphoid_T/NK-gd_T\|COVID-19_Severe / Disease group, lineage and cell class	TRGV11 RNF213 FCRL6 DGKK MYOM2 CTSW	4.50e-05	195	146	6	9990440bda7fac5d00ef80444fab07459be625e1
ToppCell	PBMC-Severe-Lymphocyte-T/NK-Other_T-gd_T\|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)	TRGV11 RNF213 FCRL6 DGKK MYOM2 CTSW	4.63e-05	196	146	6	418e8e0a51c5cb60e3b903e7d2d800dc8b9f3d5c
ToppCell	(0)_Myeloid-(010)_cDC\|(0)_Myeloid / immune cells in Peripheral Blood (logTPM normalization)	MRC1 DTNA FCRL6 NAA40 CTSW CCSER1	4.63e-05	196	146	6	ea8cf29a9d4d177d092b0568fd4601cd7f906884
ToppCell	PBMC-Severe-Lymphocyte-T/NK-Other_T-gd_T-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	TRGV11 RNF213 FCRL6 DGKK MYOM2 CTSW	4.63e-05	196	146	6	581fc8c8d42005aacd7b401a2c9d1fc331fb4af7
ToppCell	moderate-Lymphoid-Treg\|Lymphoid / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	NRIP1 RNF213 PPIB NKTR ANKRD12 IL23R	4.63e-05	196	146	6	9152f4a8a27ff4ee28f231c5ad00eb2edd9ea6da
ToppCell	PBMC-Severe-Lymphocyte-T/NK-Other_T-gd_T-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	TRGV11 RNF213 FCRL6 DGKK MYOM2 CTSW	4.63e-05	196	146	6	6beaf0c2799424c59819b286fbb5c1a83d85e4d1
ToppCell	PBMC-Severe-Lymphocyte-T/NK-Other_T-gd_T\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	TRGV11 RNF213 FCRL6 DGKK MYOM2 CTSW	4.63e-05	196	146	6	c35f2349dfe35baa845f790b9f31673dceac54c0
ToppCell	COVID_non-vent-Lymphocytic-T_cell-CD8+_Memory_T_cell\|COVID_non-vent / Disease condition, Lineage, Cell class and subclass	RNF213 FCRL6 KMT2A NKTR SH2D1A CTSW	4.76e-05	197	146	6	836061acd7f0d5de89b16f52ec679bdf09eac9db
ToppCell	COVID-19_Mild-Classical_Monocyte-cMono_4\|Classical_Monocyte / Disease condition and Cell class	NRIP1 RNF213 REL PPIB NKTR ANKRD12	4.76e-05	197	146	6	e666f6580e9a20b5e550f02125706db17eec8510
ToppCell	COVID-19_Moderate-CD8+_T_activated\|COVID-19_Moderate / disease group, cell group and cell class	DDX60 RNF213 FCRL6 MYOM2 SH2D1A CTSW	4.76e-05	197	146	6	4711ecb157e907758a5021248ae8b043d17672c6
ToppCell	Sepsis-ICU-SEP-Lymphocyte-T/NK-Treg\|ICU-SEP / Disease, condition lineage and cell class	PARG GPR82 DHX8 FSIP2 ARID5B RGPD5	4.76e-05	197	146	6	c3ee2d522fbfe67069ddba2d1abfc4f5ca230c26
ToppCell	PBMC_fresh-frozen-Severe-critical_convalescent_d14-21-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c08-IL2RB\|Severe-critical_convalescent_d14-21 / Compartment, severity and other cell annotations on 10x 3' data (130k)	RNF213 PPIB FCRL6 PPP1CA MYOM2 CTSW	4.76e-05	197	146	6	b6689a3e01e4c285fc2cb33f8c437078722a3892
ToppCell	BL-critical-LOC-Epithelial\|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	ST6GALNAC1 EPHX1 TRIM2 GSTA1 GSTA2 DNAH12	4.90e-05	198	146	6	6218a25b94d5fa2c69880539adf9c63bfe52dcd3
ToppCell	systemic_lupus_erythematosus-flare\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	SMARCA5 DDX60 RNF213 NKTR ANKRD12 SH2D1A	4.90e-05	198	146	6	4c93ee921d56132d80832d8e94563f32ccf13bbc
ToppCell	COVID-19_Mild\|World / Disease condition and Cell class	NRIP1 GRB2 RNF213 REL BLVRA DDX60L	4.90e-05	198	146	6	61ceb2245b6cb58e308b999a61d218c89dbc615e
ToppCell	3'-Broncho-tracheal-Epithelial\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ST6GALNAC1 EPHX1 PRXL2A GSTA1 DST UQCRC1	4.90e-05	198	146	6	aa6e7218ee6230902854e66c444b544218b30c0e
ToppCell	PBMC_fresh-frozen-Severe-critical_convalescent_d14-21-Lymphocytic-Lymphocytic_ILC-NK_cell-NK_c01-FCGR3A\|Severe-critical_convalescent_d14-21 / Compartment, severity and other cell annotations on 10x 3' data (130k)	RNF213 PPIB FCRL6 PPP1CA MYOM2 CTSW	4.90e-05	198	146	6	1a189b2b213099505c5d871fb8aedd55a97d44e0
ToppCell	PBMC_fresh-frozen-Severe-critical_convalescent_d14-21-Lymphocytic-Lymphocytic_ILC\|Severe-critical_convalescent_d14-21 / Compartment, severity and other cell annotations on 10x 3' data (130k)	RNF213 PPIB FCRL6 PPP1CA MYOM2 CTSW	4.90e-05	198	146	6	716c27d2a37b5f865b9d191e1851917340b400af
ToppCell	moderate-Lymphoid-CTL\|Lymphoid / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	RNF213 PPIB KMT2A NKTR ANKRD12 CTSW	4.90e-05	198	146	6	0a868098b1ee4b28b2149ed766acb09e9c0ce14c
ToppCell	PBMC_fresh-frozen-Severe-critical_convalescent_d14-21-Lymphocytic-Lymphocytic_ILC-NK_cell\|Severe-critical_convalescent_d14-21 / Compartment, severity and other cell annotations on 10x 3' data (130k)	RNF213 PPIB FCRL6 PPP1CA MYOM2 CTSW	4.90e-05	198	146	6	b12914c3c5b8dd628cb456cb40283c5016641872
ToppCell	BAL-Mild-Epithelial-Epithelial\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	ST6GALNAC1 TRIM2 DNAH7 GSTA1 GSTA2 DNAH12	5.03e-05	199	146	6	1ee4010d8557564e25e8ee00b914c2dfd9037838
ToppCell	BAL-Mild-Epithelial-Epithelial\|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)	ST6GALNAC1 TRIM2 DNAH7 GSTA1 GSTA2 DNAH12	5.03e-05	199	146	6	1df69c0cb5f759f6a2152521842506a75bb95cae
ToppCell	Mild-Epithelial-Epithelial-\|Mild / Condition, Lineage, Cell class and cell subclass	ST6GALNAC1 TRIM2 DNAH7 GSTA1 GSTA2 DNAH12	5.03e-05	199	146	6	81115bbd2c10bfdd38376d2075f03a59c31870d2
ToppCell	(04)_Interm._basal>secr.-(2)_GFP_FOXI1\|(04)_Interm._basal>secr. / shred by cell type by condition	NRIP1 NAA15 PPIB DDX46 ANKRD12 STAG2	5.03e-05	199	146	6	53ca3861f9e00dab3f3fbefb0837857ee39ab084
ToppCell	BAL-Mild-Epithelial\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	ST6GALNAC1 TRIM2 DNAH7 GSTA1 GSTA2 DNAH12	5.03e-05	199	146	6	74087b4b5e567310fc4ac58fb267ff651a180680
ToppCell	BAL-Mild-Epithelial\|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)	ST6GALNAC1 TRIM2 DNAH7 GSTA1 GSTA2 DNAH12	5.03e-05	199	146	6	00b5ce099c50a5e1786ce2b3a06ee0931a8205a4
ToppCell	Mild-Epithelial\|Mild / Condition, Lineage, Cell class and cell subclass	ST6GALNAC1 TRIM2 DNAH7 GSTA1 GSTA2 DNAH12	5.03e-05	199	146	6	ec5fff80e2a8a94fbaf1fdcc6d45c8d7c6252e18
ToppCell	Mild-Epithelial-Epithelial\|Mild / Condition, Lineage, Cell class and cell subclass	ST6GALNAC1 TRIM2 DNAH7 GSTA1 GSTA2 DNAH12	5.03e-05	199	146	6	91308b255783ad4029e5575028c18d7550832c51
ToppCell	Mild_COVID-19-Epithelial\|Mild_COVID-19 / Disease group,lineage and cell class （2021.01.30）	ST6GALNAC1 TRIM2 DNAH7 GSTA1 GSTA2 DNAH12	5.03e-05	199	146	6	72689bda7476930887ae007682fcab27f956f050
ToppCell	Bronchus_Control_(B.)-Epithelial-TX\|Bronchus_Control_(B.) / Sample group, Lineage and Cell type	ST6GALNAC1 TRIM2 PRXL2A DNAH7 GSTA1 DNAH12	5.18e-05	200	146	6	f5bc7d30aa03dd0f95eb64255bd1a2543be8d327
ToppCell	Parenchymal-10x3prime_v2-Immune_Myeloid-Myeloid-Megakaryocyte\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	AK9 SNX13 SLC9A1 BRF1 KMT2A STAG2	5.18e-05	200	146	6	0d76b006d8e8b32174e65e400acd0674354b962c
ToppCell	Parenchymal-10x3prime_v2-Immune_Myeloid-Myeloid\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	AK9 SNX13 SLC9A1 BRF1 KMT2A STAG2	5.18e-05	200	146	6	cc8368665bc6bb7c4f39632ccff07ceaa98a7b65
ToppCell	Biopsy_IPF-Epithelial\|Biopsy_IPF / Sample group, Lineage and Cell type	ST6GALNAC1 EPHX1 TRIM2 DNAH7 GSTA1 DNAH12	5.18e-05	200	146	6	76f1ac00b34d07057d8da03d276438b719b46b1d
ToppCell	COVID-19\|World / Disease, condition lineage and cell class	GRB2 RNF213 DDX3X ARID5B KMT2A ANKRD12	5.18e-05	200	146	6	7dec470c379cd89f05a0f37c8628b21f136e52f0
ToppCell	367C-Myeloid-Macrophage-SPP1+_Macrophage_2\|Myeloid / Donor, Lineage, Cell class and subclass (all cells)	SYCP2L GPX8 REL SLC9A1 ARID5B	1.12e-04	144	146	5	3ba7f8bd6d1c551048403c94693d63e60f7cbbb7
ToppCell	COVID-19-Mast_cells-Monocyte-derived_macrophages\|COVID-19 / group, cell type (main and fine annotations)	SYCP2L GPR82 ENTHD1 MTMR10 ZNF257	1.36e-04	150	146	5	10697c2d22cb25376827cc7c570ff1adc94c1acd
ToppCell	droplet-Fat-Scat-18m-Hematologic-nan\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ENPP1 PRXL2A CHRND CCSER1	1.46e-04	81	146	4	9a1cc6da6b7e697159a857c0dfe6e2a494160f9c
ToppCell	droplet-Fat-Scat-18m-Hematologic-erythroblast\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ENPP1 PRXL2A CHRND CCSER1	1.46e-04	81	146	4	40981efef1b79adaa08fd20cf87955d0ae973ca7
ToppCell	droplet-Fat-Scat-18m-Hematologic\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ENPP1 PRXL2A CHRND CCSER1	1.46e-04	81	146	4	98ee7f5a66dc29c9563cabea8160f118bcbbde73
ToppCell	10x5'-bone_marrow-Lymphocytic_T_CD4-T_CD4/CD8\|bone_marrow / Manually curated celltypes from each tissue	RANBP2 RNF213 GLS NKTR ANKRD12	1.64e-04	156	146	5	1545169694f686d28648a68b552c2ae606599d66
ToppCell	NS-moderate-d_07-13-Epithelial-FOXN4+\|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	SPATA6 AK9 DNAH7 DNAH12 DIXDC1	1.69e-04	157	146	5	410c9d74a2085179cfb39853cb6d330fa98c9c1b
ToppCell	368C-Lymphocytic-NK_cells\|368C / Donor, Lineage, Cell class and subclass (all cells)	ENPP1 FCRL6 MYOM2 CTSW IL23R	1.69e-04	157	146	5	ef5c0ace4cd500b6cc50fb7076298f3d3543b40c
ToppCell	PND03-Epithelial-Epithelial_Airway-Neurosecretory-Secretory-Secretory_mature\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	EPHX1 GFRA1 GSTA1 GSTA2 DIXDC1	1.89e-04	161	146	5	c4970501c038ed36de447da70eabff020ad78713
ToppCell	PND03-Epithelial-Epithelial_Airway-Neurosecretory-Secretory\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	EPHX1 GFRA1 GSTA1 GSTA2 DIXDC1	1.89e-04	161	146	5	41a89a3d99a9bd6039a3d881d1d9dcd18bc07f25
ToppCell	Transplant_Alveoli_and_parenchyma-Epithelial-Club\|Epithelial / Tissue, Lineage and Cell class of Lung Cells from 10X	ST6GALNAC1 GPX8 GSTA1 GSTA2 WNK2	1.95e-04	162	146	5	fe546c2272a70bb5f08e6e097b9accdb891eda23
ToppCell	10x5'-GI_small-bowel-Lymphocytic_NK-NK_CD56bright_CD16-\|GI_small-bowel / Manually curated celltypes from each tissue	N4BP3 HHIP ZFHX3 SH2D1A CTSW	2.06e-04	164	146	5	36e64e4f717dd59b352c20ff9742ca1e232342bb
ToppCell	E18.5-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK-NK-NK_G2M\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CORO2A MTMR1 RECQL NAA40 CTSW	2.12e-04	165	146	5	ec16a4979b3f203c9f66ed387a7a17bf3a1d3f86
ToppCell	Club_cells-IPF_01\|World / lung cells shred on cell class, cell subclass, sample id	ST6GALNAC1 TRIM2 GSTA1 GSTA2 WNK2	2.18e-04	166	146	5	a440aa338aa0c6cd0b5800dfa7e83f8ca16fce1a
ToppCell	5'-Adult-SmallIntestine-Hematopoietic-T_cells-CD8_Tmem\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	RNF213 FCRL6 FGF17 SH2D1A CTSW	2.24e-04	167	146	5	d80b64322d16d98c82a52724809740b9de208f39
ToppCell	3'-Parenchyma_lung-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophages-Alveolar_macrophages_L.1.6.2.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	MRC1 CORO2A CBL DHX8 P4HA1	2.24e-04	167	146	5	881f64db8dea3faa7588bf04d87c20924a4e5952
ToppCell	3'-Child09-12-SmallIntestine-Hematopoietic-T_cells-TRGV5/7_gdT\|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SPOUT1 DENND11 DDIAS SACS CTSW	2.31e-04	168	146	5	235c368669c017e13a7312fce3d8b91d7d106c7a
ToppCell	Mild/Remission-B_naive-4\|Mild/Remission / disease group and sub_cluster of B and Plasma cells(res = 0.5)	OLAH NRIP1 REL RERE RGPD5	2.37e-04	169	146	5	c3a6179a64589a370108fea809b157839347759c
ToppCell	metastatic_Lymph_Node-Myeloid_cells-CD141+_DCs\|Myeloid_cells / Location, Cell class and cell subclass	ENPP1 FCRL6 TMEM132D SH2D1A CCSER1	2.37e-04	169	146	5	a4204bdd75837f5fee9aaac459cb4c19ee2a7bf4
ToppCell	5'-Parenchyma_lung-Epithelial-Epithelial_transtional-secretory-bronchial_goblet_cell-Goblet_(bronchial)-Goblet_(bronchial)_L.0.4.2.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ST6GALNAC1 GPX8 GSTA1 PRKCG WNK2	2.37e-04	169	146	5	db73dae011ff3749b3706e50ab46d03b775dd6bb
ToppCell	5'-Parenchyma_lung-Epithelial-Epithelial_transtional-secretory-bronchial_goblet_cell-Goblet_(bronchial)\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ST6GALNAC1 GPX8 GSTA1 PRKCG WNK2	2.37e-04	169	146	5	97b7047b87ce0052d8580565c9b44fd2aa6f0d5c
ToppCell	368C-Lymphocytic-NK_cells-NK_cell_E\|368C / Donor, Lineage, Cell class and subclass (all cells)	NRIP1 ENPP1 GPR82 PIP5K1B IL23R	2.37e-04	169	146	5	0d96c0b4fd26fbc0bf44ff7bed2936eebcc55b74
ToppCell	5'-Parenchyma_lung-Epithelial-Epithelial_transtional-secretory-bronchial_goblet_cell\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ST6GALNAC1 GPX8 GSTA1 PRKCG WNK2	2.37e-04	169	146	5	1a684471dbda42e1470e5a889648666e14f25982
ToppCell	PBMC-Severe-Myeloid-cDC-cDC-cDC_0\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	MRC1 DTNA DST ZFHX3 CCSER1	2.44e-04	170	146	5	7bba77ae34a0259fad6ee98cf665ff50f77a1328
ToppCell	PBMC-Severe-Myeloid-cDC-cDC-cDC_0\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	MRC1 DTNA DST ZFHX3 CCSER1	2.44e-04	170	146	5	a43b977a7fe745536cf96b7c080397d9fa73086b
Drug	Vincamine [1617-90-9]; Down 200; 11.2uM; MCF7; HT_HG-U133A	TRIM2 WASHC4 DTNA MTMR1 CBL BRF1 KMT2A NAA40 RERE	4.98e-06	197	145	9	3865_DN
Drug	Fipexide hydrochloride [34161-23-4]; Down 200; 9.4uM; HL60; HG-U133A	NRIP1 SMARCA5 RECQL MAP3K5 DHX8 PPP1CC CTR9 WDR82 DIXDC1	5.19e-06	198	145	9	1560_DN
Disease	Small cell carcinoma of lung	INSM1 PTEN TMEM132D KMT2A TAF1L	5.10e-06	54	136	5	C0149925
Disease	Intellectual Disability	NAA15 PTEN DDX3X GTPBP2 BRF1 SACS IQSEC1 PACS2 PRKCG STAG2 TBCD	7.61e-06	447	136	11	C3714756
Disease	1,3,7-trimethylurate measurement	GSTA1 GSTA2 ARID5B	4.18e-05	15	136	3	EFO_0021172
Disease	Usher syndrome type 2	MYO7A USH2A	6.31e-05	3	136	2	C0339534
Disease	Usher syndrome (is_implicated_in)	MYO7A USH2A	1.26e-04	4	136	2	DOID:0050439 (is_implicated_in)
Disease	Hypospadias	HHIP DGKK	2.09e-04	5	136	2	C0848558
Disease	Usher Syndrome, Type II	MYO7A USH2A	2.09e-04	5	136	2	C1568249
Disease	sh2 domain-containing protein 1a measurement	SH2D1A STAG2	3.13e-04	6	136	2	EFO_0020737
Disease	acute lymphoblastic leukemia (implicated_via_orthology)	PTEN KMT2A	3.13e-04	6	136	2	DOID:9952 (implicated_via_orthology)
Disease	Child Development Disorders, Specific	PTEN CBL TBCD	3.21e-04	29	136	3	C0085997
Disease	Child Development Deviations	PTEN CBL TBCD	3.21e-04	29	136	3	C0085996
Disease	Developmental Disabilities	PTEN CBL TBCD	3.55e-04	30	136	3	C0008073
Disease	Huntington disease, disease progression measurement	MTMR10 GFRA1 BRF1	3.55e-04	30	136	3	EFO_0008336, MONDO_0007739
Disease	Malignant tumor of prostate	PTEN ZFHX3	7.43e-04	9	136	2	cv:C0376358
Disease	chronic kidney disease	ABCA4 FOXB2 MRPS30 PIP5K1B DCAF4 CCSER1	7.95e-04	235	136	6	EFO_0003884
Disease	colorectal cancer (is_marker_for)	ERCC4 PTEN CBL DDX3X ZFHX3	8.22e-04	157	136	5	DOID:9256 (is_marker_for)
Disease	Lymphoma	EPHX1 PTEN SH2D1A	8.35e-04	40	136	3	C0024299
Disease	Inherited neuropathies	COQ8A SACS PRKCG	8.35e-04	40	136	3	C0598589
Disease	Cutaneous Melanoma	ERCC4 PTEN STAG2	8.98e-04	41	136	3	C0151779
Disease	Degenerative polyarthritis	TRIM2 ESD DDX3X GLS	9.18e-04	93	136	4	C0029408
Disease	Osteoarthrosis Deformans	TRIM2 ESD DDX3X GLS	9.18e-04	93	136	4	C0086743
Disease	thyrotoxic periodic paralysis	TRIM2 ZFHX3	1.13e-03	11	136	2	MONDO_0019201
Disease	Ankylosing spondylitis	ANO6 IL23R	1.13e-03	11	136	2	C0038013
Disease	response to antidepressant	ERCC4 ENPP1 DHX8 SLC27A1 DDX54	1.37e-03	176	136	5	GO_0036276
Disease	cancer (implicated_via_orthology)	ERCC4 PTEN PPP1CA PPP1CC DST PIP5K1B	1.56e-03	268	136	6	DOID:162 (implicated_via_orthology)
Disease	L2 Acute Lymphoblastic Leukemia	EPHX1 ARID5B KMT2A	1.60e-03	50	136	3	C0023453
Disease	Childhood Acute Lymphoblastic Leukemia	EPHX1 ARID5B KMT2A	1.79e-03	52	136	3	C0023452
Disease	leukemia	PTEN KMT2A STAG2	2.11e-03	55	136	3	C0023418
Disease	hyperinsulinism (biomarker_via_orthology)	PTEN SLC27A1	2.13e-03	15	136	2	DOID:2018 (biomarker_via_orthology)
Disease	factor XI measurement, fibrinogen measurement, tissue plasminogen activator measurement, factor VII measurement	ITCH SNX13 FARP2	2.22e-03	56	136	3	EFO_0004619, EFO_0004623, EFO_0004694, EFO_0004791
Disease	central nervous system disease (implicated_via_orthology)	SMARCA5 SMARCA1	2.43e-03	16	136	2	DOID:331 (implicated_via_orthology)
Disease	Endometrial Neoplasms	RNF144B NRIP1 PTEN	2.46e-03	58	136	3	C0014170
Disease	Congenital Myasthenic Syndromes, Postsynaptic	AK9 CHRND	2.74e-03	17	136	2	C0751883
Disease	major depressive disorder (is_marker_for)	PTEN ARRB1	2.74e-03	17	136	2	DOID:1470 (is_marker_for)
Disease	non-Hodgkin lymphoma (is_implicated_in)	EPHX1 KMT2A	2.74e-03	17	136	2	DOID:0060060 (is_implicated_in)
Disease	Precursor Cell Lymphoblastic Leukemia Lymphoma	EPHX1 ARID5B KMT2A	2.84e-03	61	136	3	C1961102
Disease	Myeloid Leukemia	KMT2A STAG2	3.07e-03	18	136	2	C0023470
Disease	Tourette syndrome, schizophrenia	ENTHD1 RERE	3.07e-03	18	136	2	EFO_0004895, MONDO_0005090
Disease	Leukemia, Monocytic, Chronic	KMT2A STAG2	3.07e-03	18	136	2	C0023466
Disease	Global developmental delay	GTPBP2 IQSEC1 PACS2 STAG2	3.40e-03	133	136	4	C0557874
Disease	ankylosing spondylitis (is_implicated_in)	ANO6 IL23R	3.43e-03	19	136	2	DOID:7147 (is_implicated_in)
Disease	MYELODYSPLASTIC SYNDROME	ERCC4 CBL STAG2	3.70e-03	67	136	3	C3463824
Disease	Profound Mental Retardation	NAA15 PTEN PRKCG TBCD	3.98e-03	139	136	4	C0020796
Disease	Mental Retardation, Psychosocial	NAA15 PTEN PRKCG TBCD	3.98e-03	139	136	4	C0025363
Disease	Mental deficiency	NAA15 PTEN PRKCG TBCD	3.98e-03	139	136	4	C0917816
Disease	Endometrial Carcinoma	RNF144B NRIP1 PTEN	4.53e-03	72	136	3	C0476089

Protein segments in the cluster

Peptide	Gene	Start	Entry
KKIPVVFRLQEGYDH	ESD	246	P10768
FDPEKKRYFRLLPGH	DCAF4	71	Q8WV16
HLFQEKGYNKELRPV	CHRND	31	Q07001
FLLPNKNFKHRAYAS	ABCA4	1231	P78363
RYHFKALDPEFGTVK	DIXDC1	641	Q155Q3
RFRFLKHPEYLKVGA	GTPBP2	556	Q9BX10
LYLLFHKVQPRNKAA	ALG10B	111	Q5I7T1
PRKLGFYEQHKAIAE	CCSER1	391	Q9C0I3
ERANPYFEYLHIRKK	ANKRD12	1831	Q6UB98
LIFNNHGKPRLSKFY	AP3S1	6	Q92572
DIFYKNSLFRHPKQV	DTWD2	186	Q8NBA8
QERLIKKLGEHAYPF	ARRB1	101	P49407
ELHSNPQFYFAKAKR	CAPN14	76	A8MX76
EFKELKSNPHRDFYN	AMPD3	296	Q01432
LEYSKNPLREFLHKG	AMPD3	641	Q01432
EAHFIKRLYQGQLPF	FGF17	171	O60258
DFKLYFKNVERDPHF	MTMR1	131	Q13613
QERDPKAHRFLGLLY	RANBP2	56	P49792
YEFLLLRKIKHPGFN	SEPTIN14P20	51	C0HM01
QERDPKAHRFLGLLY	RGPD5	56	Q99666
QERDPKAHRFLGLLY	RGPD8	56	O14715
RYFPAFEKVLKSHGQ	GSTA1	131	P08263
HRYVGKEPSGLRFNK	GLS	306	O94925
FLRHYDKGPCRNKLG	RNF144B	231	Q7Z419
YKAAFPLHDCKFRRQ	ANO6	241	Q4KMQ2
PHLRNREATKGFYDK	DDX3X	41	O00571
YKLPKFGRLHNKRNV	ENTHD1	186	Q8IYW4
GDHQGIVFLRKFKQY	DGKK	501	Q5KSL6
FKHPFAIENIIGRDY	FOXB2	266	Q5VYV0
KIFYGHLLKKFRQPN	GPR82	136	Q96P67
RAKLDPLRGHYFLFD	GPN2	96	Q9H9Y4
RIYDGKKHFIFGEPR	MAGEB3	231	O15480
YKGRKHFIYGEPQEL	MAGEB17	231	A8MXT2
SKGFQRPVYLFHKAR	MEPCE	671	Q7L2J0
DRLTFDYHQKLQGKP	NUDCD3	306	Q8IVD9
AKDRTLFHNPFYIGK	MTMR10	546	Q9NXD2
RDGKLFNAIIHKYRP	DST	181	Q03001
RHYRIGLNLFNKKPE	IQSEC1	526	Q6DN90
INYSFPAKGKLFLHR	DDX54	411	Q8TDD1
FKPGQNLHFFYLVER	DDX60	56	Q8IY21
SKRHVGRQAGFPKDY	DDX60	951	Q8IY21
LANLFGRKYIPAKFQ	DDX60L	1471	Q5H9U9
PLSQVKFYRDGKFLH	FCRL6	46	Q6DN72
KGENLRVFHYENLKP	FSIP2	3296	Q5CZC0
RYFPAFEKVLKSHGQ	GSTA2	131	P09210
YFKDKIFNVAIPRFH	FBXO3	386	Q9UK99
ALHFRRYLDQFVPEK	PARG	826	Q86W56
QHKEAEFLQKLLPGY	PIP5K1B	141	O14986
HGINRAFKKPVFYSD	DDIAS	786	Q8IXT1
AYHFPDQQELPRKKL	DDIAS	891	Q8IXT1
GLNAYLEKKRLFFPR	DNAH12	981	Q6ZR08
FFHALVQERKKFGPL	DNAH12	2651	Q6ZR08
TRHLKFYNEPIGDAK	HERVK_113	851	P63132
KFSRNDLEFKYPAGH	NRIP1	901	P48552
PKARHLKFAAAYNLG	LRP2BP	126	Q9P2M1
LPRKRDYFLNNKHVG	TUBGCP6	126	Q96RT7
REPNQHFKPYLKHFL	ENPP1	481	P22413
IQQLGKFKEPHAAFY	PRKCG	446	P05129
FLKINPDHIGFYRVN	ENPEP	616	Q07075
FSLQYPHFLKREGNK	PACS2	96	Q86VP3
QHFKVLRDGAGKYFL	GRB2	106	P62993
YFLEHLAFKGTKNRP	UQCRC1	91	P31930
TRHLKFYNEPIGDAK	ERVK-7	851	P63135
AFPVFKKYDRNGLNV	NAA40	41	Q86UY6
DVLRQHPFYFKAARI	NAA15	546	Q9BXJ9
KGHPALEKLRRSYYQ	IFT172	731	Q9UG01
KKLFCRYHDGNRNPK	P4HA1	306	P13674
HAIYERKKGRGFPQT	MCAT	331	Q8IVS2
KIKYPENFFLLRGNH	PPP1CA	111	P62136
NPDHLKYFRFIGRFI	ITCH	631	Q96J02
QVGIPDLRHFLYKSK	MON1A	536	Q86VX9
KHRLKFAFPNGRNDF	GAL3ST1	101	Q99999
KNPKATLRYFQHLLG	HYOU1	91	Q9Y4L1
NRYPHFKTKIEGLDI	EPHX1	111	P07099
APRKGIYSFNFHVVK	CBLN1	106	P23435
LRQFFDKVPAKHSYG	GFRA1	196	P56159
KEHFYNRNPPARKEA	GALNT4	391	Q8N4A0
RKLFDQHKVEYGLPE	DGAT2L6	316	Q6ZPD8
HKIQSDFIYFRKGPF	DENND11	116	A4D1U4
QYRSSKFRHVFGKPA	CORO2A	6	Q92828
GLNEYLEKKRLFFPR	DNAH7	1056	Q8WXX0
PRKLHFYKNGIKERF	IL23R	61	Q5VWK5
HFRLGNLGEAKKYFL	CTR9	461	Q6PD62
SEKDYPFQGKVRAHR	CTSW	211	P56202
RKFRDLLKGHPFFYV	COQ8A	416	Q8NI60
PGLKRNRYLSFHFKS	BLVRA	221	P53004
PRFEKHLYNAAAFKA	IFRD2	476	Q12894
EKAFLAQIHARKPGY	DTNA	666	Q9Y4J8
RNYKFRFHKPEEANE	KMT2A	3741	Q03164
LQKFIHKPGSYIFRL	CBL	281	P22681
FVKLFSYPVKGQHAR	EML6	1216	Q6ZMW3
VDHGKIEYEPFRKNF	DDX46	321	Q7L014
ARKNYGVTFPIFHKI	GPX8	126	Q8TED1
YHTFFRLLDQPKPKA	FARP2	316	O94887
PQKTEKYAGIFHFRF	CAPN6	111	Q9Y6Q1
GHFYLLDPANEKLIK	OLAH	236	Q9NV23
YKLPLELGTFHQLFK	SACS	3826	Q9NZJ4
RKAFFPKHQDLQFAG	SPOUT1	156	Q5T280
FFRNAAKKDPQEGYR	DHX8	1111	Q14562
HRGKFLKAQEALDFY	PTEN	141	P60484
EKHKYFERSFNLGSP	INSM1	111	Q01101
YKKRRVHLPQEGAFE	MRC1	1411	P22897
VKFHYAFALNRRNLP	MAP3K5	351	Q99683
SEKIHFNPRFGSYKE	CWH43	666	Q9H720
LPLFKRQYENHIFVG	MRPS30	271	Q9NP92
RKYKEPQFRAIDFDH	AK9	1881	Q5TCS8
FPQYKFRELFNKLHS	SNX13	931	Q9Y5W8
ALQLKKGRLYFLFDP	USH2A	1571	O75445
LDAKIARYKAPFHQL	SMARCA1	936	P28370
AETAPGVHKRYFRKI	SH2D1A	66	O60880
FALKYRHKQVPFEEQ	TMEM132D	941	Q14C87
GGYFKDENFILKHDR	NKTR	91	P30414
FDYGFKLRKTQHEPV	TAF1L	381	Q8IZX4
ERFPDENFKLKHYGP	PPIB	121	P23284
KNVPLGKDVRYLHFL	ST6GALNAC1	431	Q9NSC7
YGKNFFRIRKELLPN	RERE	411	Q9P2R6
VYPEARKKGTHFNFA	SAP18	76	O00422
ERGLLSLAFHPNYKK	HHIP	281	Q96QV1
HIRTEVKDFQPYFKG	PRXL2A	116	Q9BRX8
FYKAFQFHLEGKPRI	ARID5B	21	Q14865
PFLKEKIANRFFLHG	TTPAL	241	Q9BTX7
FRPDYKALGILKRQF	RECQL	231	P46063
FQKRHKYSPSDVFIG	RNF213	3206	Q63HN8
DNKYIRYFPGHSKRV	WDR82	96	Q6UXN9
DRLFFLDLKQGHYLP	SLC27A1	616	Q6PCB7
HRPVAVAAGEFLYKK	STAG2	421	Q8N3U4
EKDYRLHKRFPAAFA	STOX2	31	Q9P2F5
DFPQQPKSHYRKHLF	SYCP2L	491	Q5T4T6
TRHLKFYNEPIGDAK	ERVK-10	851	P10266
TRHLKFYNEPIGDAK	ERVK-11	851	Q9UQG0
IAFSLGYLLDKKHFP	SLC9A1	461	P19634
GHRPYFLKKSEQRQL	RRP36	206	Q96EU6
EGRYFKKEPNLFSHD	REL	356	Q04864
KIKYPENFFLLRGNH	PPP1CC	111	P36873
AKHFDLNLRQFGPYR	WDR46	186	O15213
YPFREHLLQKKEFAI	SUCNR1	126	Q9BXA5
YIPRFAHLLEFGEKN	BRF1	186	Q92994
QKPNKGLEYLLHVFL	TRGV11	56	A0A075B6L2
FHVEPGLQRLFYRGK	UHRF1	36	Q96T88
RFFREIKDQNDHKYP	WASHC4	871	Q2M389
DHKYPFDRAEKFNRG	WASHC4	881	Q2M389
KGFIGRLDFYKHQVV	ZNF155	351	Q12901
GKAFTYPQAFQRHEK	ZNF57	286	Q68EA5
KVRGYKTFLRLFPHE	TBCD	111	Q9BTW9
NAIGKPFDKTIRHYL	ERCC4	256	Q92889
LKGLQHPNIVRFYDF	WNK2	246	Q9Y3S1
RLYDQHIRGSPFKLK	TRIM2	406	Q9C040
LDTKIGRYKAPFHQL	SMARCA5	921	O60264
RLAHLNLGPYEFKKE	SPATA6	236	Q9NWH7
LGFGKQYVERHFNKT	USP5	51	P45974
PFKQLERFAKQYRDH	ZFHX3	2011	Q15911
GKPFNRFSYLTVHKR	ZNF257	521	Q9Y2Q1
GQREFLSYLHLPKKD	N4BP3	51	O15049
SRFGKYIDIHFNKRG	MYO7A	211	Q13402
EKFVKYLRNFIHGGP	MYO7A	1206	Q13402
RKEFLRKQGPHFAEY	MYOM2	1121	P54296