Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionpeptide lactyltransferase (CoA-dependent) activity

CREBBP EP300

1.75e-052842GO:0120300
GeneOntologyMolecularFunctionhistone H3K27 acetyltransferase activity

CREBBP EP300

1.75e-052842GO:0044017
GeneOntologyMolecularFunctionhistone modifying activity

JARID2 NSD1 PRKCB SRCAP PADI2 CREBBP EP300

5.10e-05229847GO:0140993
GeneOntologyMolecularFunctionhistone H3K18 acetyltransferase activity

CREBBP EP300

5.23e-053842GO:0043993
GeneOntologyMolecularFunctionacyltransferase activity, transferring groups other than amino-acyl groups

FASN SPTLC2 GPAT3 SRCAP ACSM6 CREBBP EP300

6.50e-05238847GO:0016747
GeneOntologyMolecularFunctionnuclear androgen receptor binding

NSD1 PRKCB EP300

3.58e-0433843GO:0050681
GeneOntologyMolecularFunctiontau protein binding

BIN1 MAP2 EP300

9.57e-0446843GO:0048156
GeneOntologyMolecularFunctionacetyltransferase activity

FASN SRCAP CREBBP EP300

9.73e-04104844GO:0016407
GeneOntologyMolecularFunctiontranscription factor binding

JARID2 FBP1 SAP18 NSD1 PRKCB RORA PADI2 CREBBP EP300 TFDP2

1.22e-037538410GO:0008134
GeneOntologyMolecularFunctionhistone acetyltransferase activity

SRCAP CREBBP EP300

1.29e-0351843GO:0004402
GeneOntologyMolecularFunctiontransforming growth factor beta receptor activity

TGFBR3 BMPR2

1.32e-0313842GO:0005024
GeneOntologyMolecularFunctiontranscription coactivator binding

RORA CREBBP EP300

1.53e-0354843GO:0001223
GeneOntologyMolecularFunctionAP-2 adaptor complex binding

OTOF BMP2K

1.54e-0314842GO:0035612
GeneOntologyMolecularFunctionpeptide-lysine-N-acetyltransferase activity

SRCAP CREBBP EP300

1.61e-0355843GO:0061733
GeneOntologyMolecularFunctionhistone H3 acetyltransferase activity

CREBBP EP300

1.77e-0315842GO:0010484
GeneOntologyMolecularFunctionpeptide N-acetyltransferase activity

SRCAP CREBBP EP300

2.07e-0360843GO:0034212
GeneOntologyMolecularFunctiontransmembrane receptor protein serine/threonine kinase activity

TGFBR3 BMPR2

3.16e-0320842GO:0004675
GeneOntologyMolecularFunctionC-acyltransferase activity

SPTLC2 ACSM6

3.49e-0321842GO:0016408
GeneOntologyMolecularFunctionperoxisome proliferator activated receptor binding

CREBBP EP300

3.49e-0321842GO:0042975
GeneOntologyMolecularFunctionBMP binding

TGFBR3 BMPR2

3.82e-0322842GO:0036122
GeneOntologyMolecularFunctionchromatin binding

JARID2 ZNF609 SMC4 NSD1 PRKCB FANCM CREBBP EP300 POLR3A

3.84e-03739849GO:0003682
GeneOntologyMolecularFunctionATP-dependent activity

ATP6V1B1 KIF26B SMC4 SRPRA SRCAP FANCM ATP2A2 ACSM6

4.28e-03614848GO:0140657
GeneOntologyMolecularFunctionN-acetyltransferase activity

SRCAP CREBBP EP300

4.35e-0378843GO:0008080
GeneOntologyBiologicalProcessT-tubule organization

MYOF BIN1 ATP2A2

5.57e-069853GO:0033292
GeneOntologyBiologicalProcesspositive regulation of nuclear-transcribed mRNA poly(A) tail shortening

PABPC3 TNRC6C PABPC1

2.38e-0514853GO:0060213
GeneOntologyBiologicalProcessregulation of nuclear-transcribed mRNA poly(A) tail shortening

PABPC3 TNRC6C PABPC1

3.64e-0516853GO:0060211
GeneOntologyBiologicalProcesspositive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay

PABPC3 TNRC6C PABPC1

3.64e-0516853GO:1900153
GeneOntologyBiologicalProcesscanonical NF-kappaB signal transduction

TGFBR3 EDAR WNT5A EDARADD PRKCB RORA CREBBP EP300

6.51e-05330858GO:0007249
GeneOntologyBiologicalProcessN-terminal peptidyl-lysine acetylation

CREBBP EP300

1.00e-044852GO:0018076
GeneOntologyCellularComponentGtr1-Gtr2 GTPase complex

RRAGA RRAGB

9.75e-054852GO:1990131
GeneOntologyCellularComponentextrinsic component of synaptic vesicle membrane

ATP6V1B1 BIN1 RPH3A

1.40e-0425853GO:0098850
GeneOntologyCellularComponentmCRD-mediated mRNA stability complex

PABPC3 PABPC1

2.43e-046852GO:0106002
GeneOntologyCellularComponentextrinsic component of organelle membrane

ATP6V1B1 BIN1 RPH3A

7.12e-0443853GO:0031312
GeneOntologyCellularComponentexocytic vesicle membrane

ATP6V1B1 MYOF BIN1 OTOF RPH3A

8.21e-04179855GO:0099501
GeneOntologyCellularComponentsynaptic vesicle membrane

ATP6V1B1 MYOF BIN1 OTOF RPH3A

8.21e-04179855GO:0030672
HumanPhenoProminent forehead

TTC7A JARID2 EDAR WNT5A EDARADD NSD1 ALDH18A1 ITGA3 SRCAP CREBBP EP300 POLR3A

3.93e-072614012HP:0011220
HumanPhenoRidged nail

EDAR WNT5A EDARADD RNF113A ATP2A2

5.43e-0634405HP:0001807
HumanPhenoAbnormal nail surface

EDAR WNT5A EDARADD RNF113A ATP2A2

1.24e-0540405HP:0025757
HumanPhenoAplasia/Hypoplasia of the eyebrow

TTC7A JARID2 EDAR EDARADD RNF113A NSD1 ITGA3 SLC1A3 POLR3A

3.25e-05216409HP:0100840
HumanPhenoPlantar crease between first and second toes

CREBBP EP300

6.01e-052402HP:0008107
HumanPhenoAortic isthmus hypoplasia

CREBBP EP300

6.01e-052402HP:0034227
HumanPhenoHigh axial triradius

CREBBP EP300

6.01e-052402HP:0001042
HumanPhenoAvascular necrosis of the capital femoral epiphysis

WNT5A SRCAP CREBBP EP300

7.71e-0530404HP:0005743
HumanPhenoOligodontia

EDAR WNT5A EDARADD SRCAP POLR3A

1.35e-0465405HP:0000677
HumanPhenoSparse eyebrow

JARID2 EDAR EDARADD RNF113A NSD1 ITGA3 POLR3A

1.43e-04151407HP:0045075
HumanPhenoNail dysplasia

TTC7A EDAR DSG1 WNT5A EDARADD RNF113A NSD1 ITGA3 ATP2A2

1.56e-04264409HP:0002164
HumanPhenoLaryngeal cartilage malformation

CREBBP EP300

1.79e-043402HP:0008752
HumanPhenoPhobia

CREBBP EP300

1.79e-043402HP:5200232
HumanPhenoAgoraphobia

CREBBP EP300

1.79e-043402HP:0000756
HumanPhenoHumoral immunodeficiency

CREBBP EP300

1.79e-043402HP:0005363
HumanPhenoProminent nasal septum

CREBBP EP300

1.79e-043402HP:0005322
HumanPhenoHypohidrotic ectodermal dysplasia

EDAR EDARADD

1.79e-043402HP:0007607
HumanPhenoRadial deviation of thumb terminal phalanx

CREBBP EP300

1.79e-043402HP:0005895
HumanPhenoAnhidrosis

EDAR SPTLC2 EDARADD ALK

1.99e-0438404HP:0000970
HumanPhenoPremature thelarche

CREBBP ALK EP300

2.83e-0417403HP:0010314
HumanPhenoJuvenile aseptic necrosis

WNT5A SRCAP CREBBP EP300

3.23e-0443404HP:0100323
HumanPhenoTrichiasis

CREBBP EP300

3.57e-044402HP:0001128
HumanPhenoVisceral hemangioma

CREBBP EP300

3.57e-044402HP:0410266
HumanPhenoPeriorbital hyperpigmentation

EDAR EDARADD

3.57e-044402HP:0001106
HumanPhenoTalon cusp

CREBBP EP300

3.57e-044402HP:0011087
HumanPhenoWidened distal phalanges

CREBBP EP300

3.57e-044402HP:0006200
HumanPhenoVascular ring

CREBBP EP300

3.57e-044402HP:0010775
HumanPhenoHepatic hemangioma

CREBBP EP300

3.57e-044402HP:0031207
HumanPhenoHypoplasia of teeth

TTC7A EDAR EDARADD RNF113A CREBBP EP300

3.91e-04126406HP:0000685
HumanPhenoAnodontia

EDAR WNT5A EDARADD

3.98e-0419403HP:0000674
HumanPhenoAbnormality of primary teeth

EDAR WNT5A EDARADD RNF113A SRCAP

4.04e-0482405HP:0006481
HumanPhenoAdvanced eruption of teeth

NSD1 CREBBP EP300 POLR3A

4.20e-0446404HP:0006288
HumanPhenoAbsent earlobe

CREBBP EP300 POLR3A

4.66e-0420403HP:0000387
HumanPhenoRetrognathia

JARID2 BIN1 WNT5A RNF113A RTTN NSD1 SRCAP CREBBP EP300 POLR3A

4.74e-043754010HP:0000278
HumanPhenoSparse hair

TTC7A EDAR DSG1 EDARADD RNF113A NSD1 ALDH18A1 ITGA3 CREBBP POLR3A

5.61e-043834010HP:0008070
HumanPhenoPeriorbital wrinkles

EDAR EDARADD

5.92e-045402HP:0000607
HumanPhenoPapillary cystadenoma of the epididymis

CREBBP EP300

5.92e-045402HP:0009715
HumanPhenoSupernumerary cusp

CREBBP EP300

5.92e-045402HP:0033777
HumanPhenoEpididymal neoplasm

CREBBP EP300

5.92e-045402HP:0030421
HumanPhenoBroad thumb

WNT5A NSD1 SRCAP CREBBP EP300

6.22e-0490405HP:0011304
HumanPhenoAbnormal foramen magnum morphology

ALDH18A1 CREBBP EP300

7.13e-0423403HP:0002699
HumanPhenoAgenesis of permanent teeth

NSD1 CREBBP EP300

7.13e-0423403HP:0006349
HumanPhenoAbnormality of hair density

TTC7A EDAR DSG1 EDARADD RNF113A NSD1 ALDH18A1 ITGA3 CREBBP POLR3A

7.61e-043984010HP:0011357
HumanPhenoDislocated radial head

WNT5A SRCAP CREBBP EP300

7.77e-0454404HP:0003083
HumanPhenoEverted upper lip vermilion

EDAR EDARADD CREBBP

8.10e-0424403HP:0010803
HumanPhenoAbnormal fingertip morphology

JARID2 ODAD1 RNF113A SRCAP FANCM CREBBP EP300

8.75e-04203407HP:0001211
HumanPhenoLarge foramen magnum

CREBBP EP300

8.84e-046402HP:0002700
MousePhenosmall heart

TTC7A JARID2 TGFBR3 CAMK1D WNT5A RTTN CACNA1I ATP2A2 CREBBP NEURL4 EP300

7.89e-073217311MP:0002188
MousePhenoventricular hypoplasia

JARID2 TGFBR3 WNT5A ATP2A2 CREBBP EP300

1.26e-0599736MP:0000279
MousePhenoabnormal myocardium compact layer morphology

JARID2 BMPR2 ATP2A2 CREBBP EP300

2.54e-0567735MP:0004056
MousePhenoabnormal duvet hair morphology

EDAR RORA

2.69e-052732MP:0000407
MousePhenoabsent duvet hair

EDAR RORA

2.69e-052732MP:0000408
MousePhenoincreased circulating HDL cholesterol level

CT45A1 DSG1 SNX6 CT45A3 SPTLC2 CT45A2 DNTT CT45A9

3.25e-05238738MP:0001556
MousePhenoventricle myocardium hypoplasia

JARID2 TGFBR3 ATP2A2 CREBBP EP300

3.37e-0571735MP:0010502
MousePhenoabnormal cardiac muscle tissue morphology

PLIN4 JARID2 TGFBR3 BIN1 BMPR2 DSG2 SGPL1 QKI ATP2A2 CREBBP EP300

4.29e-054897311MP:0010630
MousePhenoabnormal myocardium layer morphology

JARID2 TGFBR3 BIN1 BMPR2 DSG2 SGPL1 QKI ATP2A2 CREBBP EP300

5.46e-054147310MP:0005329
MousePhenoabnormal heart layer morphology

JARID2 TGFBR3 BIN1 BMPR2 DSG2 SGPL1 QKI ATP2A2 CREBBP EP300

6.41e-054227310MP:0010545
MousePhenomyocardium hypoplasia

JARID2 TGFBR3 ATP2A2 CREBBP EP300

8.47e-0586735MP:0010500
MousePhenothin ventricle myocardium compact layer

ATP2A2 CREBBP EP300

1.46e-0420733MP:0010556
MousePhenoabsent zigzag hairs

EDAR EDARADD

1.60e-044732MP:0006366
MousePhenoabnormal vasculogenesis

TGFBR3 QKI CREBBP EP300

1.78e-0454734MP:0001622
MousePhenoheart hypoplasia

JARID2 TGFBR3 ATP2A2 CREBBP EP300

1.99e-04103735MP:0002740
MousePhenoabnormal heart size

TTC7A PRSS54 JARID2 TGFBR3 CAMK1D DSG2 KIF26B WNT5A RTTN CACNA1I QKI ATP2A2 CREBBP NEURL4 EP300 PLCE1

3.15e-0411807316MP:0005406
MousePhenoabnormal ventricle myocardium morphology

JARID2 TGFBR3 ATP2A2 CREBBP EP300

3.46e-04116735MP:0010499
DomainINT_SG_DDX_CT_C

CT45A1 CT45A3 CT45A9

5.19e-068863PF15300
DomainINT_SG_DDX_CT_C

CT45A1 CT45A3 CT45A9

5.19e-068863IPR029307
DomainNuc_rcpt_coact_CREBbp

CREBBP EP300

2.10e-052862IPR014744
DomainHAT_KAT11

CREBBP EP300

2.10e-052862PF08214
DomainKIX

CREBBP EP300

2.10e-052862PS50952
DomainZnF_TAZ

CREBBP EP300

2.10e-052862SM00551
DomainCBP_P300_HAT

CREBBP EP300

2.10e-052862IPR031162
DomainDUF902

CREBBP EP300

2.10e-052862PF06001
Domain-

CREBBP EP300

2.10e-0528621.20.1020.10
DomainRING_CBP-p300

CREBBP EP300

2.10e-052862IPR010303
Domain-

CREBBP EP300

2.10e-0528621.10.1630.10
DomainCreb_binding

CREBBP EP300

2.10e-052862PF09030
Domain-

CREBBP EP300

2.10e-0528621.10.246.20
Domainzf-TAZ

CREBBP EP300

2.10e-052862PF02135
DomainZF_TAZ

CREBBP EP300

2.10e-052862PS50134
DomainHistone_AcTrfase_Rtt109/CBP

CREBBP EP300

2.10e-052862IPR013178
DomainKAT11

CREBBP EP300

2.10e-052862SM01250
DomainZnf_TAZ

CREBBP EP300

2.10e-052862IPR000197
DomainKIX_dom

CREBBP EP300

2.10e-052862IPR003101
DomainKIX

CREBBP EP300

2.10e-052862PF02172
DomainCBP_P300_HAT

CREBBP EP300

2.10e-052862PS51727
DomainC2

MYOF OTOF PRKCB CPNE4 RPH3A PLCE1

3.15e-05131866PF00168
DomainC2

MYOF OTOF PRKCB CPNE4 RPH3A PLCE1

4.05e-05137866SM00239
DomainC2

MYOF OTOF PRKCB CPNE4 RPH3A PLCE1

4.96e-05142866PS50004
DomainRmlC_Cupin

CT45A1 CT45A3 CT45A2

5.05e-0516863IPR011051
Domain-

MYOF OTOF PRKCB CPNE4 RPH3A PLCE1

6.24e-051488662.60.40.150
DomainC2_dom

MYOF OTOF PRKCB CPNE4 RPH3A PLCE1

1.10e-04164866IPR000008
DomainDesmoglein

DSG1 DSG2

1.25e-044862IPR009123
DomainGtr1_RagA

RRAGA RRAGB

1.25e-044862PF04670
DomainGtr1_RagA

RRAGA RRAGB

1.25e-044862IPR006762
DomainFerI

MYOF OTOF

2.08e-045862SM01202
DomainFerB

MYOF OTOF

2.08e-045862SM01201
DomainFerlin_B-domain

MYOF OTOF

2.08e-045862IPR012561
DomainPolyA

PABPC3 PABPC1

2.08e-045862SM00517
DomainFerlin_C

MYOF OTOF

2.08e-045862PF16165
DomainFerlin_C

MYOF OTOF

2.08e-045862IPR032362
DomainFerIin_dom

MYOF OTOF

2.08e-045862IPR012968
DomainFerI

MYOF OTOF

2.08e-045862PF08151
DomainFerB

MYOF OTOF

2.08e-045862PF08150
Domain-

PABPC3 PABPC1

2.08e-0458621.10.1900.10
DomainPABP

PABPC3 PABPC1

2.08e-045862PF00658
DomainPABC

PABPC3 PABPC1

2.08e-045862PS51309
DomainPABP_1234

PABPC3 PABPC1

2.08e-045862IPR006515
DomainPABP_HYD

PABPC3 PABPC1

2.08e-045862IPR002004
DomainNuc_rcpt_coact

CREBBP EP300

3.11e-046862IPR009110
DomainDesmosomal_cadherin

DSG1 DSG2

4.34e-047862IPR009122
DomainZZ

CREBBP EP300

3.06e-0318862PF00569
DomainZF_ZZ_2

CREBBP EP300

3.06e-0318862PS50135
DomainZF_ZZ_1

CREBBP EP300

3.06e-0318862PS01357
DomainZnf_ZZ

CREBBP EP300

3.41e-0319862IPR000433
DomainZnF_ZZ

CREBBP EP300

3.41e-0319862SM00291
PathwayREACTOME_RORA_ACTIVATES_GENE_EXPRESSION

RORA CREBBP EP300

7.27e-0518653M26942
PathwayBIOCARTA_EIF4_PATHWAY

PABPC3 PRKCB PABPC1

1.55e-0423653MM1470
PathwayBIOCARTA_PELP1_PATHWAY

CREBBP EP300

2.07e-045652MM1575
PathwayREACTOME_NFE2L2_REGULATING_INFLAMMATION_ASSOCIATED_GENES

CREBBP EP300

2.07e-045652M48020
PathwayREACTOME_NFE2L2_REGULATING_ER_STRESS_ASSOCIATED_GENES

CREBBP EP300

2.07e-045652M48023
PathwayREACTOME_LRR_FLII_INTERACTING_PROTEIN_1_LRRFIP1_ACTIVATES_TYPE_I_IFN_PRODUCTION

CREBBP EP300

2.07e-045652M27228
PathwayREACTOME_PRE_NOTCH_EXPRESSION_AND_PROCESSING

TNRC6C ATP2A2 CREBBP EP300 TFDP2

2.17e-04119655M607
PathwayWP_PATHWAYS_AFFECTED_IN_ADENOID_CYSTIC_CARCINOMA

NSD1 SRCAP CREBBP EP300

2.26e-0465654M39682
PathwayREACTOME_TGFBR3_EXPRESSION

TGFBR3 TNRC6C EP300

2.82e-0428653M48253
PathwayBIOCARTA_PELP1_PATHWAY

CREBBP EP300

3.10e-046652M22062
PathwayBIOCARTA_PPARG_PATHWAY

CREBBP EP300

4.33e-047652MM1573
PathwayREACTOME_RUNX1_REGULATES_TRANSCRIPTION_OF_GENES_INVOLVED_IN_DIFFERENTIATION_OF_MYELOID_CELLS

PRKCB CREBBP

4.33e-047652M27799
PathwayBIOCARTA_PPARG_PATHWAY

CREBBP EP300

5.76e-048652M22058
PathwayREACTOME_NFE2L2_REGULATING_MDR_ASSOCIATED_ENZYMES

CREBBP EP300

5.76e-048652M48022
PathwayREACTOME_REGULATION_OF_NFE2L2_GENE_EXPRESSION

CREBBP EP300

5.76e-048652M48024
PathwayREACTOME_NFE2L2_REGULATES_PENTOSE_PHOSPHATE_PATHWAY_GENES

CREBBP EP300

5.76e-048652M46443
Pubmed

Identification of cancer/testis-antigen genes by massively parallel signature sequencing.

CT45A8 CT45A1 CT45A3 CT45A2 CT45A9

2.57e-101587515905330
Pubmed

Identification of a novel SNF2/SWI2 protein family member, SRCAP, which interacts with CREB-binding protein.

SRCAP CREBBP EP300

1.51e-08387310347196
Pubmed

Adenovirus DNA binding protein interacts with the SNF2-related CBP activator protein (SrCap) and inhibits SrCap-mediated transcription.

SRCAP CREBBP EP300

6.04e-08487311581372
Pubmed

Irisin Mediates Effects on Bone and Fat via αV Integrin Receptors.

PLIN4 FASN RBM12 BMP2K SAP18 SPTLC2 SGPL1 PABPC3 WDR20 OSBPL11 ALDH18A1 SRPRA CPSF2 SQOR ATP2A2 PABPC1 EP300

9.95e-081451871730550785
Pubmed

Ex vivo Quantitative Proteomic Analysis of Serotonin Transporter Interactome: Network Impact of the SERT Ala56 Coding Variant.

BIN1 OXCT1 BMP2K SGPL1 PABPC3 CPSF2 SQOR PABPC1 SLC1A3 RPH3A

1.29e-07430871032581705
Pubmed

Network organization of the huntingtin proteomic interactome in mammalian brain.

FASN BIN1 MAP2 BMP2K PABPC3 ZRANB2 PRKCB ATP2A2 PABPC1 SLC1A3 RPH3A

4.42e-07621871122794259
Pubmed

The Eyes Absent family members EYA4 and EYA1 promote PLK1 activation and successful mitosis through tyrosine dephosphorylation.

ZNF609 RBM12 TNRC6C QKI CREBBP EP300

2.38e-0615287638360978
Pubmed

Control of hippocampal morphogenesis and neuronal differentiation by the LIM homeobox gene Lhx5.

CALB2 MAP2 WNT5A

2.46e-061187310325223
Pubmed

Roles of tau protein in health and disease.

BIN1 MAP2 CREBBP EP300

3.12e-064087428386764
Pubmed

Interaction of tau with the RNA-Binding Protein TIA1 Regulates tau Pathophysiology and Toxicity.

PABPC3 PRKCB AHCYL2 ATP2A2 PABPC1 RPH3A

3.96e-0616687627160897
Pubmed

The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.

JARID2 MYOF DSG2 BMP2K SGPL1 WDR20 NOL6 ZRANB2 SMC4 NSD1 ALDH18A1 SRPRA CPSF2 SQOR ATP2A2

4.28e-061497871531527615
Pubmed

A protein interaction landscape of breast cancer.

JARID2 DSG2 BMP2K SAP18 SPTLC2 SGPL1 GPAT3 ALDH18A1 SQOR TFDP2

4.28e-06634871034591612
Pubmed

Interpreting cancer genomes using systematic host network perturbations by tumour virus proteins.

MYOF SPTLC2 SGPL1 SRPRA SQOR ATP2A2 CREBBP EP300 TFDP2

4.57e-0649987922810586
Pubmed

ISG15 Connects Autophagy and IFN-γ-Dependent Control of Toxoplasma gondii Infection in Human Cells.

MYOF FASN DSG2 BMP2K SQOR ATP2A2 PABPC1

5.15e-0626887733024031
Pubmed

Mammalian miRNA RISC recruits CAF1 and PABP to affect PABP-dependent deadenylation.

PABPC3 TNRC6C PABPC1

5.39e-061487319716330
Pubmed

From the Cover: Indispensability of the glutamate transporters GLAST and GLT1 to brain development.

CALB2 MAP2 SLC1A3

5.39e-061487316880397
Pubmed

Loss of p300 accelerates MDS-associated leukemogenesis.

CREBBP EP300

6.19e-06287227881875
Pubmed

Molecular characterization of the histone acetyltransferase CREBBP/EP300 genes in myeloid neoplasia.

CREBBP EP300

6.19e-06287234845315
Pubmed

p300 plays a critical role in maintaining cardiac mitochondrial function and cell survival in postnatal hearts.

CREBBP EP300

6.19e-06287219729597
Pubmed

Ferlin Overview: From Membrane to Cancer Biology.

MYOF OTOF

6.19e-06287231443490
Pubmed

CREB-binding protein/P300 bromodomain inhibition reduces neutrophil accumulation and activates antitumor immunity in triple-negative breast cancer.

CREBBP EP300

6.19e-06287239287984
Pubmed

Identification and Characterization of p300-Mediated Lysine Residues in Cardiac SERCA2a.

ATP2A2 EP300

6.19e-06287236834924
Pubmed

Exon deletions of the EP300 and CREBBP genes in two children with Rubinstein-Taybi syndrome detected by aCGH.

CREBBP EP300

6.19e-06287220717166
Pubmed

The epigenetic regulators CBP and p300 facilitate leukemogenesis and represent therapeutic targets in acute myeloid leukemia.

CREBBP EP300

6.19e-06287225893291
Pubmed

Human T-lymphotropic virus type 1 p30(II) regulates gene transcription by binding CREB binding protein/p300.

CREBBP EP300

6.19e-06287211559821
Pubmed

CARM1 inhibition reduces histone acetyltransferase activity causing synthetic lethality in CREBBP/EP300-mutated lymphomas.

CREBBP EP300

6.19e-06287232576962
Pubmed

Syndromic features and mild cognitive impairment in mice with genetic reduction on p300 activity: Differential contribution of p300 and CBP to Rubinstein-Taybi syndrome etiology.

CREBBP EP300

6.19e-06287219822209
Pubmed

A specific CBP/p300-dependent gene expression programme drives the metabolic remodelling in late stages of spermatogenesis.

CREBBP EP300

6.19e-06287224522976
Pubmed

Tandem arrangement of the closely linked desmoglein genes on human chromosome 18.

DSG1 DSG2

6.19e-0628727790000
Pubmed

CBP is required for environmental enrichment-induced neurogenesis and cognitive enhancement.

CREBBP EP300

6.19e-06287221847097
Pubmed

Negative Expression of DSG1 and DSG2, as Prognostic Biomarkers, Impacts on the Overall Survival in Patients with Extrahepatic Cholangiocarcinoma.

DSG1 DSG2

6.19e-06287232850288
Pubmed

The promoter of the Poly(A) binding protein 2 (Pabp2) retroposon is derived from the 5'-untranslated region of the Pabp1 progenitor gene.

PABPC3 PABPC1

6.19e-06287210534404
Pubmed

p300 or CBP is required for insulin-stimulated glucose uptake in skeletal muscle and adipocytes.

CREBBP EP300

6.19e-06287234813504
Pubmed

Rubinstein-Taybi Syndrome

CREBBP EP300

6.19e-06287220301699
Pubmed

Novel member of the mouse desmoglein gene family: Dsg1-beta.

DSG1 DSG2

6.19e-06287212631242
Pubmed

Potential biomarker of metformin action.

CREBBP EP300

6.19e-06287224639469
Pubmed

The histone acetyl transferases CBP and p300 regulate stress response pathways in synovial fibroblasts at transcriptional and functional levels.

CREBBP EP300

6.19e-06287237816914
Pubmed

Binding of p300/CBP co-activators by polyoma large T antigen.

CREBBP EP300

6.19e-06287211438528
Pubmed

Smad-dependent stimulation of type I collagen gene expression in human skin fibroblasts by TGF-beta involves functional cooperation with p300/CBP transcriptional coactivators.

CREBBP EP300

6.19e-06287210918613
Pubmed

Histone Acetyltransferases p300 and CBP Coordinate Distinct Chromatin Remodeling Programs in Vascular Smooth Muscle Plasticity.

CREBBP EP300

6.19e-06287235502657
Pubmed

p300 and cAMP response element-binding protein-binding protein in skeletal muscle homeostasis, contractile function, and survival.

CREBBP EP300

6.19e-06287231898871
Pubmed

Germline or inducible knockout of p300 or CBP in skeletal muscle does not alter insulin sensitivity.

CREBBP EP300

6.19e-06287230888860
Pubmed

Exploitation of EP300 and CREBBP Lysine Acetyltransferases by Cancer.

CREBBP EP300

6.19e-06287227881443
Pubmed

Spatiotemporal expression of histone acetyltransferases, p300 and CBP, in developing embryonic hearts.

CREBBP EP300

6.19e-06287219272189
Pubmed

Nucleotide sequence of a mouse testis poly(A) binding protein cDNA.

PABPC3 PABPC1

6.19e-0628721630930
Pubmed

Differential contribution of p300 and CBP to regulatory element acetylation in mESCs.

CREBBP EP300

6.19e-06287232690000
Pubmed

CBP/p300 antagonises EGFR-Ras-Erk signalling and suppresses increased Ras-Erk signalling-induced tumour formation in mice.

CREBBP EP300

6.19e-06287230953353
Pubmed

Disrupting the CH1 domain structure in the acetyltransferases CBP and p300 results in lean mice with increased metabolic control.

CREBBP EP300

6.19e-06287221803292
Pubmed

Mutations in SRCAP, encoding SNF2-related CREBBP activator protein, cause Floating-Harbor syndrome.

SRCAP CREBBP

6.19e-06287222265015
Pubmed

HIV-1 tat transactivator recruits p300 and CREB-binding protein histone acetyltransferases to the viral promoter.

CREBBP EP300

6.19e-0628729811832
Pubmed

Two independent regions of simian virus 40 T antigen increase CBP/p300 levels, alter patterns of cellular histone acetylation, and immortalize primary cells.

CREBBP EP300

6.19e-06287224089570
Pubmed

Genetic heterogeneity in Rubinstein-Taybi syndrome: mutations in both the CBP and EP300 genes cause disease.

CREBBP EP300

6.19e-06287215706485
Pubmed

Developmental expression of poly(A) binding protein mRNAs during spermatogenesis in the mouse.

PABPC3 PABPC1

6.19e-0628727893484
Pubmed

AR coactivators, CBP/p300, are critical mediators of DNA repair in prostate cancer.

CREBBP EP300

6.19e-06287239266679
Pubmed

A boy with classical Rubinstein-Taybi syndrome but no detectable mutation in the CREBBP and EP300 genes.

CREBBP EP300

6.19e-06287222303793
Pubmed

Inhibition of histone acetyltransferase function radiosensitizes CREBBP/EP300 mutants via repression of homologous recombination, potentially targeting a gain of function.

CREBBP EP300

6.19e-06287234732714
Pubmed

Cloning of a novel family of mammalian GTP-binding proteins (RagA, RagBs, RagB1) with remote similarity to the Ras-related GTPases.

RRAGA RRAGB

6.19e-0628727499430
Pubmed

Targeting histone acetylation dynamics and oncogenic transcription by catalytic P300/CBP inhibition.

CREBBP EP300

6.19e-06287234019788
Pubmed

Characterization of two cytoplasmic poly(A)-binding proteins, PABPC1 and PABPC2, in mouse spermatogenic cells.

PABPC3 PABPC1

6.19e-06287219020299
Pubmed

Endogenous CCAAT/enhancer binding protein beta and p300 are both regulated by growth hormone to mediate transcriptional activation.

CREBBP EP300

6.19e-06287215860545
Pubmed

Further delineation of an entity caused by CREBBP and EP300 mutations but not resembling Rubinstein-Taybi syndrome.

CREBBP EP300

6.19e-06287229460469
Pubmed

Expression of p300 and CBP is associated with poor prognosis in small cell lung cancer.

CREBBP EP300

6.19e-06287224551300
Pubmed

Genome-wide CRISPR screens reveal synthetic lethal interaction between CREBBP and EP300 in diffuse large B-cell lymphoma.

CREBBP EP300

6.19e-06287233911074
Pubmed

The adenovirus 12 E1A proteins can bind directly to proteins of the p300 transcription co-activator family, including the CREB-binding protein CBP and p300.

CREBBP EP300

6.19e-0628729018065
Pubmed

Coactivators p300 and CBP maintain the identity of mouse embryonic stem cells by mediating long-range chromatin structure.

CREBBP EP300

6.19e-06287224648406
Pubmed

CBP and P300 regulate distinct gene networks required for human primary myoblast differentiation and muscle integrity.

CREBBP EP300

6.19e-06287230135524
Pubmed

Combination Therapy with STAT3 Inhibitor Enhances SERCA2a-Induced BMPR2 Expression and Inhibits Pulmonary Arterial Hypertension.

BMPR2 ATP2A2

6.19e-06287234502015
Pubmed

Distribution of co-activators CBP and p300 during mouse oocyte and embryo development.

CREBBP EP300

6.19e-06287216596650
Pubmed

The p300 and CBP Transcriptional Coactivators Are Required for β-Cell and α-Cell Proliferation.

CREBBP EP300

6.19e-06287229217654
Pubmed

Functional compensation for the loss of testis-specific poly(A)-binding protein, PABPC2, during mouse spermatogenesis.

PABPC3 PABPC1

6.19e-06287226971890
Pubmed

Structural insights into the human GW182-PABC interaction in microRNA-mediated deadenylation.

TNRC6C PABPC1

6.19e-06287220098421
Pubmed

Differences in the interactions of oncogenic adenovirus 12 early region 1A and nononcogenic adenovirus 2 early region 1A with the cellular coactivators p300 and CBP.

CREBBP EP300

6.19e-06287210049825
Pubmed

CBP/p300 acetyltransferase activity in hematologic malignancies.

CREBBP EP300

6.19e-06287227380996
Pubmed

CREBBP and p300 lysine acetyl transferases in the DNA damage response.

CREBBP EP300

6.19e-06287229170789
Pubmed

Crebbp haploinsufficiency in mice alters the bone marrow microenvironment, leading to loss of stem cells and excessive myelopoiesis.

CREBBP EP300

6.19e-06287221555743
Pubmed

CBP/p300 induction is required for retinoic acid sensitivity in human mammary cells.

CREBBP EP300

6.19e-06287212646247
Pubmed

P300 acetyltransferase regulates fatty acid synthase expression, lipid metabolism and prostate cancer growth.

FASN EP300

6.19e-06287226934656
Pubmed

Histone acetyltransferase activities of cAMP-regulated enhancer-binding protein and p300 in tissues of fetal, young, and old mice.

CREBBP EP300

6.19e-06287211867645
Pubmed

Levels of free PABP are limited by newly polyadenylated mRNA in early Spisula embryogenesis.

PABPC3 PABPC1

6.19e-06287210954604
Pubmed

Expression of the nuclear coactivators CBP and p300 in developing craniofacial tissue.

CREBBP EP300

6.19e-06287211963968
Pubmed

Differential transcriptional activation by human T-cell leukemia virus type 1 Tax mutants is mediated by distinct interactions with CREB binding protein and p300.

CREBBP EP300

6.19e-0628729528808
Pubmed

Analysis of genetic stability at the EP300 and CREBBP loci in a panel of cancer cell lines.

CREBBP EP300

6.19e-06287212696060
Pubmed

The mouse gene encoding the testis-specific isoform of Poly(A) binding protein (Pabp2) is an expressed retroposon: intimations that gene expression in spermatogenic cells facilitates the creation of new genes.

PABPC3 PABPC1

6.19e-0628729732454
Pubmed

CBP Is Required for Establishing Adaptive Gene Programs in the Adult Mouse Brain.

CREBBP EP300

6.19e-06287236109165
Pubmed

Retinoids and retinoic acid receptors regulate growth arrest and apoptosis in human mammary epithelial cells and modulate expression of CBP/p300.

CREBBP EP300

6.19e-06287212242694
Pubmed

CBP/p300 Drives the Differentiation of Regulatory T Cells through Transcriptional and Non-Transcriptional Mechanisms.

CREBBP EP300

6.19e-06287231182547
Pubmed

Rubinstein-Taybi syndrome in a Saudi boy with distinct features and variants in both the CREBBP and EP300 genes: a case report.

CREBBP EP300

6.19e-06287230635043
Pubmed

Phenotype and genotype in 52 patients with Rubinstein-Taybi syndrome caused by EP300 mutations.

CREBBP EP300

6.19e-06287227648933
Pubmed

Homozygous variants of EDAR underlying hypohidrotic ectodermal dysplasia in three consanguineous families.

EDAR EDARADD

6.19e-06287232819890
Pubmed

Developmentally regulated expression of the transcriptional cofactors/histone acetyltransferases CBP and p300 during mouse embryogenesis.

CREBBP EP300

6.19e-06287210610021
Pubmed

Emerging roles of p300/CBP in autophagy and autophagy-related human disorders.

CREBBP EP300

6.19e-06287237314181
Pubmed

Distinct roles for CREB-binding protein and p300 in hematopoietic stem cell self-renewal.

CREBBP EP300

6.19e-06287212397173
Pubmed

CBP/p300 TAZ1 domain forms a structured scaffold for ligand binding.

CREBBP EP300

6.19e-06287215641773
Pubmed

Interaction of human immunodeficiency virus type 1 Tat with the transcriptional coactivators p300 and CREB binding protein.

CREBBP EP300

6.19e-0628729733868
Pubmed

Rubinstein-Taybi syndrome in Chinese population with four novel mutations.

CREBBP EP300

6.19e-06287233063428
Pubmed

EP300/CBP is crucial for cAMP-PKA pathway to alleviate podocyte dedifferentiation via targeting Notch3 signaling.

CREBBP EP300

6.19e-06287234506759
Pubmed

Lack of somatic mutations in the catalytic domains of CREBBP and EP300 genes implies a role for histone deacetylase inhibition in myeloproliferative neoplasms.

CREBBP EP300

6.19e-06287222177454
Pubmed

Death receptor signaling giving life to ectodermal organs.

EDAR EDARADD

6.19e-06287211997580
Pubmed

RagA is a functional homologue of S. cerevisiae Gtr1p involved in the Ran/Gsp1-GTPase pathway.

RRAGA RRAGB

6.19e-0628729394008
Pubmed

Uncovering a mammalian neural-specific poly(A) binding protein with unique properties.

MAP2 PABPC3 PABPC1

6.73e-061587337704377
InteractionGATA3 interactions

ZNF609 RBM12 RNF113A CPSF2 QKI CREBBP EP300

1.42e-05187857int:GATA3
InteractionSLC6A4 interactions

BIN1 OXCT1 BMP2K SGPL1 ITGA3 CPSF2 SQOR PABPC1 SLC1A3 RPH3A

1.52e-054378510int:SLC6A4
InteractionRORA interactions

NSD1 RORA CREBBP EP300

2.17e-0539854int:RORA
CytobandEnsembl 112 genes in cytogenetic band chrXq26

CT45A8 CT45A1 CT45A3 CT45A2 CT45A9

1.95e-05171875chrXq26
CytobandXq26.3

CT45A1 CT45A3 CT45A2

2.88e-0467873Xq26.3
GeneFamilyFerlin family

MYOF OTOF

1.40e-046562828
GeneFamilyDesmosomal cadherins

DSG1 DSG2

1.96e-0475621188
GeneFamilyZinc fingers ZZ-type|Lysine acetyltransferases

CREBBP EP300

1.24e-0317562486
GeneFamilyZinc fingers ZZ-type|Lysine acetyltransferases

CREBBP EP300

1.40e-031856291
CoexpressionHE_LIM_SUN_FETAL_LUNG_C0_MYOFIBROBLAST_1_CELL

CT45A8 CT45A1 CT45A3 WNT5A CT45A2 CT45A9

1.14e-0769876M45681
CoexpressionGSE8621_UNSTIM_VS_LPS_PRIMED_AND_LPS_STIM_MACROPHAGE_DN

PRSS54 CAMK1D HOXD9 BMP2K PRKCB WDFY4 CREBBP DNTT

3.35e-07199878M6987
CoexpressionHE_LIM_SUN_FETAL_LUNG_C0_MYOFIBROBLAST_2_CELL

CT45A8 CT45A1 CT45A3 WNT5A CT45A2 CT45A9

1.31e-06104876M45682
CoexpressionKAECH_NAIVE_VS_MEMORY_CD8_TCELL_UP

JARID2 OXCT1 SMC4 PRKCB SRCAP SQOR DNTT

4.73e-06200877M3020
CoexpressionGSE3565_DUSP1_VS_WT_SPLENOCYTES_POST_LPS_INJECTION_DN

TGFBR3 KIF26B SAP18 SPTLC2 RORA CACNA1I

1.47e-05158876M6333
CoexpressionGSE27241_WT_VS_RORGT_KO_TH17_POLARIZED_CD4_TCELL_TREATED_WITH_DIGOXIN_UP

FASN BMPR2 CAMK1D ATP2A2 CREBBP EP300

3.07e-05180876M8239
CoexpressionGSE3920_IFNA_VS_IFNG_TREATED_FIBROBLAST_DN

TGFBR3 FASN ODAD1 PRKCB RORA ITGA3

3.81e-05187876M6691
CoexpressionGSE26669_CTRL_VS_COSTIM_BLOCK_MLR_CD8_TCELL_DN

MYOF PRKCB SRCAP WDFY4 CREBBP DNTT

5.53e-05200876M4667
CoexpressionGSE9650_NAIVE_VS_MEMORY_CD8_TCELL_UP

JARID2 OXCT1 SMC4 PRKCB POLR3A DNTT

5.53e-05200876M5831
CoexpressionGSE35685_CD34POS_CD38NEG_VS_CD34POS_CD10NEG_CD62LPOS_BONE_MARROW_DN

JARID2 DSG2 BMP2K SNX6 WDR20 OSBPL11

5.53e-05200876M9084
CoexpressionKAECH_NAIVE_VS_DAY15_EFF_CD8_TCELL_UP

OXCT1 SMC4 SRCAP SQOR POLR3A DNTT

5.53e-05200876M3014
CoexpressionKYNG_DNA_DAMAGE_UP

HOXD9 SGPL1 WNT5A CACNA1I SLC1A3 TFDP2

6.34e-05205876M3961
CoexpressionMULLIGHAN_NPM1_MUTATED_SIGNATURE_2_UP

MCHR1 SMC4 CACNA1I ALK TFDP2

7.41e-05130875M6590
CoexpressionNUYTTEN_NIPP1_TARGETS_DN

BMPR2 RBM12 BMP2K SPTLC2 PABPC3 OSBPL11 SRPRA ITGA3 ATP2A2 PABPC1 PLCE1

1.10e-048458711M18090
CoexpressionBOYLAN_MULTIPLE_MYELOMA_C_D_UP

PABPC3 EDARADD GPAT3 CPSF2 PABPC1

1.16e-04143875MM788
CoexpressionMULLIGHAN_NPM1_SIGNATURE_3_UP

MCHR1 WNT5A SMC4 CACNA1I RBKS ALK TFDP2

1.27e-04335877M10277
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ATP6V1B1 DSG2 SPTLC2 EDARADD GPAT3 AHCYL2

1.12e-061748665f4436863a40f8bca46e2989bca66c02b6be88d4
ToppCellControl-Myeloid-Dendritic_cells|Control / group, cell type (main and fine annotations)

JARID2 CAMK1D BMP2K PRKCB PADI2 SLC1A3

1.36e-0618086625ad95c3c30e3b82abe93bd77ba003f5c2241f7c
ToppCellImmune_cells-large_pre-B.|World / Lineage and Cell class

BIN1 EDARADD SMC4 PRKCB WDFY4 DNTT

1.50e-0618386681b5ed6ed661d2d6a9b807fefd2f0d59bd4ea77e
ToppCellfacs-Skin-Telogen-3m-Epithelial-Basal_IFE|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CAMK1D DSG2 WNT5A EDARADD RORA ITGA3

1.75e-061888668cc927b4c51d982fdafa04dc7393617ad9bb220e
ToppCellCOVID-19-Heart-Macrophage|COVID-19 / Disease (COVID-19 only), tissue and cell type

JARID2 CAMK1D BMP2K PRKCB WDFY4 SLC1A3

1.81e-061898662586f4088721c5debec86c2b211b739fd33713eb
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Myeloid-Macrophage_Dendritic-M2_Macrophage|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

CAMK1D BMP2K SNX6 PRKCB WDFY4 SLC1A3

2.10e-061948661dce6d4b6ac41f80677e3e4c335a4f383bd76f85
ToppCellBronchial-NucSeq-Immune_Myeloid-Mast_cell-Mast_cell|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

CALB2 BMP2K EDARADD GPAT3 PRKCB PADI2

2.29e-06197866bed8a9b73af5caee51b1232b31c24a59353658df
ToppCellBronchial-NucSeq-Immune_Myeloid-Mast_cell|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

CALB2 BMP2K EDARADD GPAT3 PRKCB PADI2

2.29e-06197866b7d5073d44aa1e2cb83ea8d8104c5ed662665755
ToppCellParenchymal-10x3prime_v2-Immune_Myeloid-Myeloid-Megakaryocyte|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

JARID2 CALB2 CAMK1D BMP2K PRKCB ITGA3

2.50e-062008660d76b006d8e8b32174e65e400acd0674354b962c
ToppCellParenchymal-10x3prime_v2-Immune_Myeloid-Myeloid|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

JARID2 CALB2 CAMK1D BMP2K PRKCB ITGA3

2.50e-06200866cc8368665bc6bb7c4f39632ccff07ceaa98a7b65
ToppCelldroplet-Heart-nan-3m-Hematologic-nan|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BNIP3L PADI2 WDFY4 PABPC1 TFDP2

7.72e-06140865ab90f6f30d89761687f8836e3d327d143ce49ed4
ToppCellwk_15-18-Mesenchymal-Myofibro_&_SMC-Myofibro_2|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

CT45A1 EDAR WNT5A CT45A2 CT45A9

1.35e-05157865b9d04ee417c0d8ea0801d10f1c54e138587009fd
ToppCellVE-mono3|VE / Condition, Cell_class and T cell subcluster

PABPC3 WNT5A GPAT3 PADI2 SLC1A3

1.52e-051618657df3fefc55ab43b897fc78d1f0c7383b10ac33d5
ToppCellVE-mono3-|VE / Condition, Cell_class and T cell subcluster

PABPC3 WNT5A GPAT3 PADI2 SLC1A3

1.52e-051618654e45bf7eceb0ee30dec4d8852778366776ea5a8f
ToppCelldroplet-Liver-Hepatocytes-24m-Myeloid-Kupffer_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RTTN PRKCB CPNE4 WDFY4 SLC1A3

1.61e-051638658dc0128eeede933537e3bcc5d6ec0322711552f3
ToppCelldroplet-Liver-Hepatocytes-24m-Myeloid-Kupffer_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RTTN PRKCB CPNE4 WDFY4 SLC1A3

1.61e-05163865fd243ca223079033be480a24817a399f281fa4d4
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Outer_Medullary_Collecting_Duct_Intercalated_Cell_Type_A|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ATP6V1B1 OXCT1 DSG2 SPTLC2 ACSM6

1.71e-05165865a6c6de17fec678ad0cac3138dde3a14cc39ffd26
ToppCellControl-Mast_cells|Control / group, cell type (main and fine annotations)

CALB2 BMP2K EDARADD GPAT3 PRKCB

1.92e-05169865fdb9abca1d0f4fdc32dd8ac6231651ef34aa5afb
ToppCellCOVID-19-lung-MAST|lung / Disease (COVID-19 only), tissue and cell type

CALB2 BMP2K GPAT3 PRKCB PADI2

1.97e-05170865e90f18e5462381b38e918442b38b1c8105291908
ToppCellControl-Mast_cells-Mast_cells|Control / group, cell type (main and fine annotations)

CALB2 BMP2K EDARADD GPAT3 PRKCB

1.97e-05170865c80f6d29096c372da95a8407f402349ff1bb7018
ToppCell3'_v3-lymph-node_spleen-Myeloid_Dendritic-migDC|lymph-node_spleen / Manually curated celltypes from each tissue

CFAP47 DSG2 BMP2K WNT5A CPNE4

2.09e-051728651b24bed3cd8e3fa463c5e7cefdf9e99e639e2f84
ToppCellnormal_Lymph_Node-Myeloid_cells-CD163+CD14+_DCs|normal_Lymph_Node / Location, Cell class and cell subclass

PLIN4 FHAD1 MYOF FBP1 GPAT3

2.15e-0517386538f88f5bbf92a3bf5109bc4782cd071b7cb1ca34
ToppCellE16.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-SCMF-SCMF_mature|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

TGFBR3 BMPR2 FBP1 BMP2K WNT5A

2.27e-051758651d8aab491dcc27ea5dbfb6462d18ee280b21a05e
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Cortical_Collecting_Duct_Intercalated_Cell_Type_A|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

DSG2 SPTLC2 EDARADD GPAT3 AHCYL2

2.27e-0517586577c16e615c0fb9c83f29d7e0a547be72635fac81
ToppCellE16.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-SCMF|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

TGFBR3 BMPR2 FBP1 BMP2K WNT5A

2.27e-05175865427a7ee92fe16a90625946492062d37aa0f7235b
ToppCellCOVID-19-lung-MAST|COVID-19 / Disease (COVID-19 only), tissue and cell type

CALB2 BMP2K GPAT3 PRKCB PADI2

2.33e-05176865473c45a381ca109207d66ed1635668b391ea0e1f
ToppCell10x_3'_v2v3-Non-neoplastic-Myeloid-TAM-MG-TAM-MG_prolif-E|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

MYOF WNT5A ALDH18A1 SQOR WDFY4

2.46e-0517886530d2b54462fd16222ad2e3806be6143e834b29e0
ToppCellCOVID-19-APC-like|COVID-19 / group, cell type (main and fine annotations)

CAMK1D GPAT3 PRKCB PADI2 WDFY4

2.81e-05183865b8f5afaf9ff1b2b1bc60be58654d1b23859dafa9
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L2-4_PVALB_C8orf4|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

KIF26B GPAT3 QKI ALK PLCE1

2.89e-051848652ba98708dfd7f1b2a661578a334684094ff453ad
ToppCellTCGA-Pancreas-Primary_Tumor-Pancreatic_Adenocarcinoma-Ductal_Adenocarcinoma-1|TCGA-Pancreas / Sample_Type by Project: Shred V9

BMPR2 EDAR OSBPL11 CREBBP EP300

3.04e-0518686503db813598b67b1e08f759758a1c2023396921fa
ToppCelldroplet-Spleen-nan-3m-Lymphocytic-B_cell|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYOF BIN1 BMP2K EDARADD PRKCB

3.20e-051888658b1485e63cd4020ba5334a8d4b84725b164549bf
ToppCellChildren_(3_yrs)-Immune-alveolar_macrophage_(MARCO_positive)-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

FHAD1 CAMK1D OSBPL11 WDFY4 ALK

3.20e-05188865d7a9fb5b021e127b8d927658a55a71098d513b5c
ToppCell3'-GW_trimst-2-LargeIntestine-Hematopoietic-B_cells|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TTC7A PRKCB WDFY4 QRSL1 DNTT

3.28e-05189865a12ca69eebc88725272c89d71a57fc6ce0c06813
ToppCellwk_15-18-Mesenchymal-Myofibro_&_SMC-Myofibro_1|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

CT45A1 EDAR WNT5A CT45A2 CT45A9

3.36e-05190865d24af6af3271e34afab744352afd28be8a7cc5c3
ToppCellwk_08-11-Mesenchymal-Myofibro_&_SMC-Myofibro_1|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

CT45A1 EDAR WNT5A CT45A2 CT45A9

3.36e-0519086571a00f63fdd4eb4cc6f190d37e7a0417cdaafacb
ToppCellMonocytes-Tissue-resident_macrophages|Monocytes / Immune cells in Kidney/Urine in Lupus Nephritis

CAMK1D BMP2K WNT5A PADI2 SLC1A3

3.62e-05193865198552810dcac8d0ca63a78badd6702b49ff6edf
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid-Monocytic-Monocyte-derived_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CAMK1D BMP2K PRKCB WDFY4 SLC1A3

3.62e-051938653e3d7cb3e7242ec9c9677e07e303835649852b52
ToppCellAdult-Immune-interstitial_macrophage_(C1Q_positive)|Adult / Lineage, Cell type, age group and donor

CAMK1D BMP2K SNX6 PRKCB SLC1A3

3.62e-0519386531c0978ba78c9516d498aec0798902e57555e557
ToppCellAdult-Immune-interstitial_macrophage_(C1Q_positive)-D231|Adult / Lineage, Cell type, age group and donor

JARID2 CAMK1D BMP2K GPAT3 PRKCB

3.71e-05194865800d3d7a9e864d2d6a100a4e4af22f45d5790a8d
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CALB2 KIF26B QKI ALK PLCE1

3.71e-051948654f758718a1233c25c25d99fc1b7b06f906b8b0a2
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CALB2 KIF26B QKI ALK PLCE1

3.71e-0519486502a9cc821c2b14aa7d0e55661a5fab66364474e1
ToppCell367C-Epithelial_cells-Epithelial-B_(AT2)|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

FASN CALB2 SMC4 CPSF2

3.76e-0597864eab10b1af9cd0ce373cd4d0316e0d7b218630584
ToppCell367C-Epithelial_cells-Epithelial-B_(AT2)-|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

FASN CALB2 SMC4 CPSF2

3.76e-059786404f571708f2487b0dbd70ee507de6bf75be5f5d9
ToppCellmedial-2-Hematologic-Myeloid_Dendritic_Type_2|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

JARID2 BIN1 CAMK1D GPAT3 PADI2

3.81e-0519586554a404ee1b97d0659fcffafb20d11f878ed453d4
ToppCellmedial-Hematologic-Myeloid_Dendritic_Type_2|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

JARID2 BIN1 CAMK1D GPAT3 PADI2

3.81e-05195865c0d1ecb378bb482a8e08d7065fcca07a65687dac
ToppCellChildren_(3_yrs)-Immune-monocyte-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

JARID2 CAMK1D SPTLC2 PRKCB SLC1A3

3.81e-0519586581a28289eda1a8a1a31b7357106f64ac5000e172
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Immune-Myeloid-Monocytic-Monocyte-derived_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

JARID2 CAMK1D GPAT3 PRKCB PADI2

3.81e-0519586562dc745e1aa3e2e58afa16c7bb2cf9b03d4e8105
ToppCellmedial-Hematologic-Myeloid_Dendritic_Type_2-2|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

JARID2 BIN1 CAMK1D GPAT3 PADI2

3.81e-0519586535a5302b8b3e76bc92dc38979400c979f0e86550
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Cortical_Collecting_Duct_Intercalated_Cell_Type_A|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ATP6V1B1 OXCT1 DSG2 SPTLC2 GPAT3

3.81e-05195865f7d9adadd37209ce1a38e5d621607b9c9270fed8
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Myeloid-Macrophage_Dendritic|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

CAMK1D BMP2K PRKCB WDFY4 SLC1A3

3.81e-0519586534a9462f4e843f3065cc58c17ad71c1b5b836ae1
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CAMK1D BMP2K PRKCB WDFY4 SLC1A3

3.90e-051968654370473693d2dd4a8c451a4c477eb79baa33ae12
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CALB2 KIF26B QKI ALK PLCE1

3.90e-051968657af6c5147ac859353504d19727dbe24f63a29dd4
ToppCellmild-low-quality_cells|mild / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

TGFBR3 RTTN RORA CACNA1I TNRC6C

4.00e-05197865e4331969bd911d1ebb5453f40a7057297b5389b4
ToppCellCOVID-19-kidney-Macrophages|COVID-19 / Disease (COVID-19 only), tissue and cell type

JARID2 BMP2K PRKCB WDFY4 SLC1A3

4.00e-051978653912301018d0863144dcfac8d1fa8adc081748d7
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Immune|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

JARID2 CAMK1D PRKCB WDFY4 SLC1A3

4.00e-05197865c9b1f2ee7eb31a66af331c5aae29e1bbb5186f5a
ToppCellCOVID-19-lung-Macrophage_LDB2hi_OSMRhi_YAP1hi|lung / Disease (COVID-19 only), tissue and cell type

JARID2 BMP2K PRKCB WDFY4 SLC1A3

4.00e-051978653896729740d151f0eb845f1961c7b969bfbdd28d
ToppCell10x_3'_v2v3-Non-neoplastic-Myeloid-TAM-MG-TAM-MG_aging_sig-F|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

BIN1 BMP2K WNT5A PADI2 SLC1A3

4.00e-0519786550f994e0d4e69019ec92e164edf3e4e951333766
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid-Monocytic-Monocyte-derived_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CAMK1D BMP2K PRKCB WDFY4 SLC1A3

4.00e-05197865826cc6baafab13e7ef5cfcf28cd79d0fbf3af38d
ToppCellParenchymal-NucSeq-Immune_Myeloid-Macrophage_alveolar|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

FHAD1 FBP1 OSBPL11 WDFY4 SLC1A3

4.09e-05198865e125eb8aa57c172e5518874da1bd25998292f5e2
ToppCellParenchymal-NucSeq-Immune_Myeloid-Macrophage_alveolar-Macro_alveolar|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

FHAD1 FBP1 OSBPL11 WDFY4 SLC1A3

4.09e-051988650baeb8e2c199ff10bb5c829c523546af3c9227c1
ToppCellFetal_29-31_weeks-Immune|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

JARID2 CAMK1D BMP2K PRKCB WDFY4

4.09e-051988655dff131356b8c22743bd27b2b21f86ee6e4a0a0d
ToppCell10x_5'_v1-Non-neoplastic-Myeloid-TAM-MG|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

BIN1 BMP2K QKI PADI2 SLC1A3

4.09e-051988659aced8bdb56ee52866a0a9766a84336961bc4443
ToppCellControl|World / disease group and sub_cluster of B and Plasma cells(res = 0.5)

BIN1 CAMK1D PRKCB WDFY4 PABPC1

4.09e-0519886573694b6109c1f6878b6b5997e434bbc3cec1dc70
ToppCelldistal-Hematologic-Classical_Monocyte-1|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

JARID2 PRKCB PADI2 PABPC1 SLC1A3

4.19e-05199865cd691f1c2493516d7553cc9a005f6e3b442bdbd5
ToppCellParenchymal-NucSeq-Immune_Myeloid-Mast_cell|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

CALB2 BMP2K GPAT3 PRKCB PADI2

4.29e-052008659156f8fd61a833891d2f7b7fadd693b81b1e2d5a
ToppCellNeuronal-Inhibitory|Neuronal / cells hierarchy compared to all cells using T-Statistic

CALB2 KIF26B QKI ALK PLCE1

4.29e-052008659ff8647e2de0b538e15929dca88ebb20ff7ab043
ToppCellBronchial-NucSeq-Immune_Myeloid-Macrophage_alveolar|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

FHAD1 FBP1 OSBPL11 WDFY4 SLC1A3

4.29e-05200865a443e475e7a10c26a6173d1af961de6219e0e567
ToppCellParenchymal-NucSeq-Immune_Myeloid-Mast_cell-Mast_cell|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

CALB2 BMP2K GPAT3 PRKCB PADI2

4.29e-05200865566fe2e78e6f35399ec6aad5964f6d4d8ade82c6
ToppCellParenchymal-10x5prime-Immune_Myeloid-Mast_cell-Mast_cell|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

CALB2 BMP2K EDARADD GPAT3 PADI2

4.29e-052008658943278190f42016ee914e584d1b6b9aeaf7c73f
ToppCellBronchial-NucSeq-Immune_Myeloid-Macrophage_alveolar-Macro_alveolar|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

FHAD1 FBP1 OSBPL11 WDFY4 SLC1A3

4.29e-05200865ed785a6d08ca2b350dc3307b587eadfb2886d1f9
ToppCellParenchymal-10x5prime-Immune_Myeloid-Mast_cell|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

CALB2 BMP2K EDARADD GPAT3 PADI2

4.29e-05200865ea52df18400550b65de142d03b3b0963436e03d9
ToppCelldroplet-Heart-nan-3m-Hematologic-erythrocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BNIP3L PABPC1 TFDP2

9.03e-05458638caef8096e4231e30465a4ac5ed20ac4248c51ea
ToppCellPBMC-Control-Myeloid-Classical_Monocyte-Classical_Monocyte-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

MYOF RBKS SQOR SLC1A3

1.70e-041438644c5a5db46beb8f2f3c40e8ed95911fbfea61bae0
ToppCellSmart-seq2-lymph_node_(Smart-seq2)-lymphocytic-T_lymphocytic-T_cell|lymph_node_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

FASN EDARADD RORA CACNA1I

2.04e-04150864c922dbb4c9c12ccf08bd5f6168b20606c605d052
ToppCellVE-CD8-memory_CD4|VE / Condition, Cell_class and T cell subcluster

TGFBR3 FASN RORA KCTD21

2.14e-041528649401b7770c1bdc87eba25e82922f5dd1c4fa37ee
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Cortical_Collecting_Duct_Intercalated_Cell_Type_A|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

DSG2 EDARADD GPAT3 AHCYL2

2.14e-041528649391b46a441cf031665df1d142e3f65e98675eeb
ToppCellCOVID-19-Heart-Adipocyte|COVID-19 / Disease (COVID-19 only), tissue and cell type

PLIN4 TGFBR3 FASN CALB2

2.20e-0415386493958bd9c951222ba5b740d1cb83fd5d78a10e1e
ToppCellfacs-Aorta-Heart-18m-Mesenchymal-fibrocyte|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EDAR PRKCB PADI2 ALK

2.37e-041568645b56217336771baf57d791efcb4e206c6aea83b1
ToppCellCOVID-19-Mast_cells-Mast_cells|COVID-19 / group, cell type (main and fine annotations)

CALB2 BMP2K GPAT3 PADI2

2.37e-04156864bc10b94673184ef384c6665b16a1209a8975a4f1
ToppCellCOVID-19-Mast_cells|COVID-19 / group, cell type (main and fine annotations)

CALB2 BMP2K GPAT3 PADI2

2.37e-04156864159504d43421ee83b9ab484816333ae549c9c2fd
ToppCelldroplet-Liver-Hepatocytes-24m-Myeloid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RTTN PRKCB CPNE4 WDFY4

2.43e-04157864ec433d2fe827abdb647be4176c231b7052482b6f
ToppCellPND10-Immune-Immune_Myeloid-DC-cDC1-cDC1_mature|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CAMK1D OTOF RRAGB WDFY4

2.55e-04159864807ee55fe0d3645fbfb98f641dd0a0555b847cf5
ToppCellPND10-Immune-Immune_Myeloid-DC-cDC1|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CAMK1D OTOF RRAGB WDFY4

2.55e-041598647bb76324d2026d4bd348126cb169c8411f0d7145
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-Adaptive_/_Maladaptive_/_Repairing_Fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PLIN4 FASN SLC1A3 ALK

2.67e-041618644f25eeabb841b0b9204cdd4e71d5e131e7868184
ToppCellPND03-Immune-Immune_Myeloid-DC|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CAMK1D BMP2K RRAGB WDFY4

2.67e-04161864f50e91f8363f20bb7c565aaca4d4961d3fe4b5b5
ToppCellASK428-Immune-Mast_cell|ASK428 / Donor, Lineage and Cell class of Lung cells from Dropseq

CALB2 BMP2K PRKCB PADI2

2.80e-04163864569ca0e8ce307f258910b0c75c498009a9651e6e
ToppCellP07-Endothelial-lymphatic_endothelial_cell|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

HOXD9 EDARADD RPH3A PLCE1

2.80e-041638645cbab3d03bb1af9391ecad635d6eea1dd42c1337
ToppCellCOVID-mono3|COVID / Condition, Cell_class and T cell subcluster

FHAD1 CALB2 PADI2 SLC1A3

2.80e-041638646ab4cbcd411b40920b81162c0f4b03ea67408f52
ToppCellP07-Endothelial-lymphatic_endothelial_cell-endothelial_cell_of_lymphatic_vessel|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

HOXD9 EDARADD RPH3A PLCE1

2.80e-04163864322ba94c3ec1e1859c2e2195ecb3f7dab8d190f6
ToppCellCOVID-mono3-|COVID / Condition, Cell_class and T cell subcluster

FHAD1 CALB2 PADI2 SLC1A3

2.80e-0416386426661c7a3a0a449ed32d4b3b28fc2fc0b237025d
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22-Myeloid-Monocytic-Nonclassical_Monocyte|Severe-critical_progression_d12-22 / Compartment, severity and other cell annotations on 10x 3' data (130k)

MYOF FBP1 SLC1A3 NEURL4

2.86e-0416486417d5b8bb7c015cf9f0d6e578a0d212eada39cb93
ToppCellfacs-Heart-RA-24m-Lymphocytic-B_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PRKCB CACNA1I WDFY4 ALK

2.93e-0416586436415924d05373e9dd3665be599f4f3f40bf0497
ToppCellfacs-Heart-RA-24m-Lymphocytic-B_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PRKCB CACNA1I WDFY4 ALK

2.93e-0416586456310fddd3d8e4afdfde066d26cee9747e5b8c6a
ToppCellfacs-Kidney-nan-3m-Lymphocytic-B_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BIN1 GPAT3 PRKCB CACNA1I

3.00e-041668646a948aefd283a2572da37b59dbc142b6e686b024
ToppCellfacs-Kidney-nan-3m-Lymphocytic-B_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BIN1 GPAT3 PRKCB CACNA1I

3.00e-041668648d0c4eb90a2c006f96ae61d3d94c96fb64bc0c4d
ToppCell10x5'-Liver-Hematopoietic_progenitors|Liver / Manually curated celltypes from each tissue

KIF26B ODAD1 GPAT3 FANCM

3.00e-04166864ae967570248cf86ca3ddf55e33bcbb3e4e3684bc
ToppCell10x5'-Liver-Hematopoietic_progenitors-Cycling_pre-Myeloid-2|Liver / Manually curated celltypes from each tissue

KIF26B ODAD1 GPAT3 FANCM

3.00e-04166864a176e87aa6eec81d1fb79a028f759182d11b567d
ToppCellTracheal-10x3prime_v2-Immune_Myeloid-Macrophage_other-Macrophage_intermediate|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

JARID2 RBM12 EP300

3.09e-0468863f1cbc6d72489272c1eb6200f64b8b6444719acda
ToppCell5'-GW_trimst-2-LymphNode-Hematopoietic-B_cells-Pro-B|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TTC7A PRKCB QRSL1 DNTT

3.14e-04168864c833e3311af2582787d3ff2ad59d802fff865f8f
ToppCellPND07-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_B-B-B_mature|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

EDARADD PRKCB WDFY4 PABPC1

3.14e-04168864943687a33fffd7e19d906b9dd385a126bcea109a
Drug15d-PGJ2; Up 200; 10uM; PC3; HG-U133A

BMPR2 CALB2 RBKS AHCYL2 PADI2 SLC1A3 TFDP2

8.24e-06194857446_UP
DrugTrichostatin A, from Streptomyces sp.; Up 200; 0.1uM; HL60; HT_HG-U133A

MYOF BMPR2 RRAGB AHCYL2 PADI2 SLC1A3 TFDP2

8.52e-061958572566_UP
DrugMerbromin [129-16-8]; Up 200; 5uM; HL60; HT_HG-U133A

BIN1 BMPR2 CALB2 AHCYL2 PADI2 RPH3A TFDP2

9.41e-061988572577_UP
DrugPridinol methanesulfonate salt [6856-31-1]; Up 200; 10.2uM; HL60; HT_HG-U133A

TGFBR3 BIN1 ZNF609 FBP1 QKI SLC1A3 ALK

9.41e-061988572715_UP
Drug5-aza-2′-deoxycytidine; Down 200; 0.1uM; MCF7; HT_HG-U133A_EA

BIN1 ZNF609 BMP2K SPTLC2 AHCYL2 QKI QRSL1

9.73e-06199857920_DN
DrugLithocholic acid [434-13-9]; Down 200; 10.6uM; MCF7; HT_HG-U133A

BIN1 CAMK1D MAP2 CACNA1I ATP2A2 ALK

9.11e-051958564373_DN
Drugrapamycin, Streptomyces hygroscepicus; Up 200; 0.1uM; MCF7; HT_HG-U133A

BIN1 ZNF609 SGPL1 SRPRA QKI TFDP2

9.37e-051968565975_UP
DrugMephenytoin [50-12-4]; Up 200; 18.4uM; HL60; HT_HG-U133A

ATP6V1B1 SGPL1 CACNA1I SLC1A3 ALK PLCE1

9.37e-051968566158_UP
Drug2-propylpentanoic acid; Up 200; 500uM; HL60; HT_HG-U133A

BIN1 ZNF609 BMP2K SPTLC2 RRAGB TFDP2

9.37e-051968561181_UP
DrugHexamethonium dibromide dihydrate [55-97-0]; Up 200; 10uM; MCF7; HT_HG-U133A

BIN1 ZNF609 SMC4 CACNA1I SRCAP RPH3A

9.37e-051968564965_UP
DrugCanrenoic acid potassium salt [2181-04-6]; Down 200; 10uM; PC3; HT_HG-U133A

BIN1 SAP18 SRPRA SRCAP QKI EP300

9.37e-051968562065_DN
DrugCefamandole sodium salt [30034-03-8]; Up 200; 8.2uM; MCF7; HT_HG-U133A

EDAR SPTLC2 CACNA1I RRAGB SRCAP QKI

9.37e-051968564718_UP
Drugaspirin, USP; Up 200; 100uM; MCF7; HT_HG-U133A

BIN1 WNT5A SMC4 CACNA1I QKI QRSL1

9.64e-051978566964_UP
DrugSerotonin hydrochloride [153-98-0]; Up 200; 18.8uM; MCF7; HT_HG-U133A

ATP6V1B1 ZNF609 CAMK1D SPTLC2 CACNA1I QKI

9.64e-051978563311_UP
DrugDoxepin hydrochloride [1229-29-4]; Up 200; 12.6uM; HL60; HT_HG-U133A

MYOF FASN ZNF609 HOXD9 RBKS RRAGB

9.64e-051978562384_UP
Drugclozapine; Up 200; 10uM; MCF7; HT_HG-U133A

MYOF ZNF609 CALB2 EDAR BMP2K AHCYL2

9.64e-051978566947_UP
Drug0198306-0000 [212631-61-3]; Down 200; 10uM; PC3; HT_HG-U133A

MYOF BIN1 BMPR2 RNF113A SRCAP ATP2A2

9.64e-051978567069_DN
DrugChlorhexidine [55-56-1]; Up 200; 8uM; MCF7; HT_HG-U133A

ATP6V1B1 RORA CACNA1I RRAGB SRCAP CREBBP

9.64e-051978565403_UP
DrugMimosine [500-44-7]; Down 200; 20.2uM; MCF7; HT_HG-U133A

BIN1 BMP2K SPTLC2 SGPL1 SRCAP QRSL1

9.64e-051978562638_DN
DrugAlclometasone dipropionate [667634-13-2]; Down 200; 7.6uM; HL60; HT_HG-U133A

MYOF ZNF609 EDAR BMP2K TFDP2 PLCE1

9.64e-051978562532_DN
DrugClenbuterol hydrochloride [21898-19-1]; Down 200; 12.8uM; MCF7; HT_HG-U133A

MYOF BIN1 ZNF609 EDAR AHCYL2 SRCAP

9.64e-051978563228_DN
DrugNorethynodrel [68-23-5]; Down 200; 13.4uM; PC3; HT_HG-U133A

BMP2K SAP18 SRCAP QKI SLC1A3 EP300

9.91e-051988561818_DN
DrugGlutethimide, para-amino [125-84-8]; Up 200; 17.2uM; MCF7; HT_HG-U133A

MYOF ZNF609 SPTLC2 SRCAP QKI QRSL1

9.91e-051988567421_UP
DrugOleandomycin phosphate [7060-74-4]; Down 200; 5uM; PC3; HT_HG-U133A

ZNF609 SPTLC2 SRPRA CACNA1I QKI PLCE1

1.02e-041998564615_DN
DrugUngerine nitrate; Up 200; 10.2uM; MCF7; HT_HG-U133A

BIN1 CAMK1D PRKCB SRCAP ALK RPH3A

1.02e-041998566076_UP
DrugAlfadolone acetate [23930-37-2]; Down 200; 10.2uM; PC3; HT_HG-U133A

BIN1 SPTLC2 WNT5A AHCYL2 QKI QRSL1

1.02e-041998567262_DN
DrugClebopride maleate [84370-95-6]; Down 200; 8.2uM; HL60; HT_HG-U133A

ZNF609 SPTLC2 SMC4 SRPRA RBKS AHCYL2

1.02e-041998561292_DN
DrugDyclonine hydrochloride [536-43-6]; Up 200; 12.2uM; HL60; HT_HG-U133A

MYOF ZNF609 SPTLC2 RBKS CREBBP ALK

1.02e-041998562392_UP
DrugDimaprit dihydrochloride [23256-33-9]; Up 200; 17uM; MCF7; HT_HG-U133A

MYOF ZNF609 CALB2 BMP2K NOL6 SRCAP

1.05e-042008567480_UP
DiseaseMenke-Hennekam syndrome

CREBBP EP300

7.26e-062802cv:C5681632
DiseaseRubinstein-Taybi syndrome (implicated_via_orthology)

CREBBP EP300

7.26e-062802DOID:1933 (implicated_via_orthology)
DiseaseEctodermal dysplasia 10B, hypohidrotic/hair/tooth type, autosomal recessive

EDAR EDARADD

7.26e-062802cv:C3887494
DiseaseRubinstein-Taybi syndrome

CREBBP EP300

7.26e-062802cv:C0035934
DiseaseRUBINSTEIN-TAYBI SYNDROME 1

CREBBP EP300

7.26e-062802C4551859
DiseaseAutosomal hypohidrotic ectodermal dysplasia

EDAR EDARADD

7.26e-062802cv:CN118829
DiseaseRUBINSTEIN-TAYBI SYNDROME 1

CREBBP EP300

7.26e-062802180849
DiseaseRubinstein-Taybi syndrome due to CREBBP mutations

CREBBP EP300

7.26e-062802cv:C4551859
DiseaseECTODERMAL DYSPLASIA 10B, HYPOHIDROTIC/HAIR/TOOTH TYPE, AUTOSOMAL RECESSIVE

EDAR EDARADD

7.26e-062802224900
DiseaseEctodermal Dysplasia 3, Anhidrotic

EDAR EDARADD

7.26e-062802C1720965
DiseaseEctodermal dysplasia 10A, hypohidrotic/hair/nail type, autosomal dominant

EDAR EDARADD

7.26e-062802cv:C3888065
DiseaseRubinstein-Taybi syndrome (is_implicated_in)

CREBBP EP300

7.26e-062802DOID:1933 (is_implicated_in)
DiseaseECTODERMAL DYSPLASIA 10A, HYPOHIDROTIC/HAIR/NAIL TYPE, AUTOSOMAL DOMINANT

EDAR EDARADD

7.26e-062802129490
DiseaseRubinstein-Taybi Syndrome

CREBBP EP300

7.26e-062802C0035934
DiseaseHypohidrotic ectodermal dysplasia

EDAR EDARADD

2.17e-053802cv:C5848103
DiseaseAutosomal recessive hypohidrotic ectodermal dysplasia syndrome

EDAR EDARADD

2.17e-053802cv:C0406702
Diseaseresponse to thiazide, QT interval

CAMK1D CREBBP

2.17e-053802EFO_0004682, EFO_0007981
DiseaseEctodermal Dysplasia, Hypohidrotic, Autosomal Recessive

EDAR EDARADD

2.17e-053802C0406702
Diseasehypohidrotic ectodermal dysplasia (implicated_via_orthology)

EDAR EDARADD

4.34e-054802DOID:14793 (implicated_via_orthology)
DiseaseAutosomal dominant hypohidrotic ectodermal dysplasia syndrome (disorder)

EDAR EDARADD

4.34e-054802C0265331
Diseasecoronary aneurysm

FHAD1 CAMK1D CPNE4

1.18e-0435803EFO_1000881
DiseaseSquamous cell carcinoma of esophagus

FASN CREBBP EP300 PLCE1

1.32e-0495804C0279626
Diseasepsoriasis (implicated_via_orthology)

TTC7A SPTLC2

1.51e-047802DOID:8893 (implicated_via_orthology)
Diseaselimb-girdle muscular dystrophy (implicated_via_orthology)

MYOF OTOF

1.51e-047802DOID:11724 (implicated_via_orthology)
DiseaseAdenoid Cystic Carcinoma

NSD1 SRCAP CREBBP EP300

1.61e-04100804C0010606
DiseaseCarcinoma, Transitional Cell

PABPC1 CREBBP EP300

1.90e-0441803C0007138
DiseaseAdenocarcinoma of lung (disorder)

FASN ALDH18A1 CREBBP ALK EP300

2.48e-04206805C0152013
Diseasehair morphology measurement

EDAR OSBPL11 QKI

4.31e-0454803EFO_0007821
DiseaseDiffuse Large B-Cell Lymphoma

CREBBP ALK EP300

4.55e-0455803C0079744
DiseaseHeadache

TGFBR3 CAMK1D CHSY3

7.10e-0464803HP_0002315
DiseaseAutistic Disorder

NSD1 PRKCB RORA WDFY4 SLC1A3

7.30e-04261805C0004352
Diseasepro-hydroxy-pro measurement

WNT5A ALK

8.50e-0416802EFO_0021132
Diseaseheart disease (biomarker_via_orthology)

ATP2A2 EP300

9.61e-0417802DOID:114 (biomarker_via_orthology)
DiseaseAlzheimer disease, psychotic symptoms

BIN1 TNRC6C

9.61e-0417802EFO_0005940, MONDO_0004975
DiseaseLeukemia, Myelocytic, Acute

NSD1 FANCM CREBBP EP300

1.28e-03173804C0023467
Diseasecitrulline measurement

KIF26B ALDH18A1

1.34e-0320802EFO_0009777
DiseaseIntellectual Disability

FASN RNF113A RTTN NSD1 RORA QKI

1.37e-03447806C3714756
Diseasecalcium measurement

FBP1 CAMK1D MCHR1 RORA ATP2A2 PABPC1 PLCE1

1.59e-03628807EFO_0004838
DiseaseRenal glomerular disease

CREBBP PLCE1

1.77e-0323802C0268731
DiseaseGlomerulopathy Assessment

CREBBP PLCE1

1.77e-0323802C4521256
Diseaseobsessive-compulsive disorder, attention deficit hyperactivity disorder, Tourette syndrome, unipolar depression, bipolar disorder, autism spectrum disorder, schizophrenia, anorexia nervosa

RORA CACNA1I RBKS ATP2A2

2.17e-03200804EFO_0003756, EFO_0003761, EFO_0003888, EFO_0004242, EFO_0004895, MONDO_0004985, MONDO_0005090, MONDO_0005351
Diseasetriacylglycerol 56:5 measurement

PRKCB ALK

2.26e-0326802EFO_0010432
Diseaseschizophrenia, intelligence, self reported educational attainment

BNIP3L CAMK1D RORA CACNA1I ATP2A2

2.52e-03346805EFO_0004337, EFO_0004784, MONDO_0005090

Protein segments in the cluster

PeptideGeneStartEntry
MGQKKTMGTERSRGG

nan

1

A8MZ25
MAIFFTKGTTGAPKM

ACSM6

221

Q6P461
KPGMKARFVDSGEMA

EP300

1336

Q09472
LMMKGEGSRKGSFFK

CPSF2

441

Q9P2I0
VKPGMKSRFVDSGEM

CREBBP

1371

Q92793
MKKFSRMPKSEGGSG

BMP2K

1

Q9NSY1
QSGKGDMVEMATRFG

R3HCC1

221

Q9Y3T6
GMMRTGGTIKGSKVT

RBM12

56

Q9NTZ6
MEGDVSSKDKMGKGV

NSD1

1816

Q96L73
ETGCKIMVRGKGSMR

QKI

116

Q96PU8
TSAKVMMEGGRSKGF

PABPC1

321

P11940
GAMTSMVCKVGKDSF

RBKS

66

Q9H477
GVGGMAKEATMKGSS

DSG2

686

Q14126
AMFSGKMPTKRDSQG

KCTD21

31

Q4G0X4
RMEKSGKGGMSGGRS

KIF26B

691

Q2KJY2
FGLKRDEIGGMTDGM

EDAR

381

Q9UNE0
LCGIMDGTKGMTRSK

FANCM

386

Q8IYD8
GGTVMGESGMKTVED

ITGA3

776

P26006
FTGFSKDRMMQKPGS

CT45A3

76

Q8NHU0
FKASSTKGRMVMSRG

NOL6

1096

Q9H6R4
MLGGSAGRLKMSSSG

HOXD9

1

P28356
MVLGKGSFGKVMLSE

PRKCB

346

P05771
EAIMFKGLGGMSSKR

PADI2

511

Q9Y2J8
MVSAAGLSGDGKMRG

PRSS54

1

Q6PEW0
KDTSMGNASSGMVRK

RNF113A

166

O15541
LGVKTSMGDRDMGLF

ODAD1

396

Q96M63
MTGFELTEGVKTSGM

DSG1

651

Q02413
TSAKVMMEGGRSKGF

PABPC3

321

Q9H361
TFGTKSRVGMGGMEA

ALDH18A1

296

P54886
SRVGMGGMEAKVKAA

ALDH18A1

301

P54886
AYVMEKAGGMATTGK

FBP1

286

P09467
TSMSKMFVKGAPEGV

ATP2A2

506

P16615
FTGFSKDRMMQKPGS

CT45A1

76

Q5HYN5
FTGFSKDRMMQKPGS

CT45A9

76

P0DMV2
ARFGSAMEKSGKMDV

FHAD1

1221

B1AJZ9
MGKTNLDEFAMGSGS

QRSL1

116

Q9H0R6
SVMMFKKGSFEIGGT

GPAT3

311

Q53EU6
VGFSSDKKMGGDDVM

FRRS1L

146

Q9P0K9
TGMAALDSKASGKMG

SLC1A3

106

P43003
GRMPSIAKDVFTKMG

CACNA1I

1096

Q9P0X4
TSTFKEMRGAMEGKQ

CPNE4

246

Q96A23
FTGFSKDRMMQKPGS

CT45A2

76

Q5DJT8
EGGTATTMVSKDIGM

BMPR2

1021

Q13873
SLSMRKSGAMKKGGI

BNIP3L

166

O60238
MSVGAMKKGVGRAVG

MCHR1

1

Q99705
FTGFSKDRMMQKPGS

CT45A8

76

P0DMV1
MGLRTTKQMGRGTKA

EDARADD

1

Q8WWZ3
ARKGSGMMSKSDNFG

CALB2

51

P22676
MEFSGRDASGKRVMG

FASN

1601

P49327
MAEMGSKGVTAGKIA

BIN1

1

O00499
KGKITGGGMVDVMCS

CFAP47

461

Q6ZTR5
GKSAGTQGDMEKADM

NEURL4

1301

Q96JN8
SMGKADFMGRTFAKP

OTOF

1041

Q9HC10
KSKFLGMSIGVTMVG

OSBPL11

536

Q9BXB4
RMSSLGAGVTSAKKM

JARID2

311

Q92833
SSGVTGAMDMAKGAV

PLIN4

126

Q96Q06
GGNAMSFMGKGVTKS

RTTN

1311

Q86VV8
MKSAIGEGMTRKDHG

ATP6V1B1

396

P15313
GGSGGITMAARMKRK

SQOR

51

Q9Y6N5
SVSGGDGKMDTMIGD

TNRC6C

66

Q9HCJ0
PMKRAGTTGSARGMA

RPH3A

521

Q9Y2J0
GLKRTTDMMFGGKQV

AHCYL2

381

Q96HN2
AFVTMTGGFRRGKKM

DNTT

326

P04053
IKGGMKGFQSFMVSD

PLCE1

1196

Q9P212
MSGSMDKGTLGSGSK

POLR3A

646

O14802
MATEGGGKEMNEIKT

WDR20

1

Q8TBZ3
IGSTMSGRKGTDDSM

SAP18

106

O00422
KGMGGAMDLVSSAKT

OXCT1

421

P55809
LEAEGMRGRKSGGSM

SRCAP

3071

Q6ZRS2
IMISDFGLSKMEGKG

CAMK1D

161

Q8IU85
FGLSKMEGKGDVMST

CAMK1D

166

Q8IU85
KRMGMSFGLESGKCS

TFDP2

316

Q14188
KAKTTGMGAIYGMAQ

SGPL1

516

O95470
AAGGKGGKNTMMRSH

ALK

741

Q9UM73
MKGEFSRGLGLEMAS

CHSY3

691

Q70JA7
VGMSRDAVKFGRMSK

RORA

136

P35398
DVMMGTFTKSFGASG

SPTLC2

371

O15270
LLMGKSGSGKTSMRS

RRAGA

11

Q7L523
GKSPFRESSGDGMKM

ZNF609

756

O15014
MTSGGDAAMFRDGKE

WDFY4

1931

Q6ZS81
EQSGTMTGGGSKVMK

SMC4

746

Q9NTJ3
SATKGTLGGMFGMLK

SRPRA

311

P08240
MGKSGSGKTSMRSII

RRAGB

46

Q5VZM2
GVALGMAGSAMSSKF

WNT5A

11

P41221
GEGEGSMTKEEFTKM

SNX6

111

Q9UNH7
FMGVESGHMKEGTKV

MAP2

1091

P11137
EAKMMKAGGTEIGKT

ZRANB2

41

O95218
GSFGEGLTMKKQSGM

TTC7A

646

Q9ULT0
GFGKESERSMTMTKS

TGFBR3

301

Q03167
EDTSSGSKGYMKVSM

MYOF

306

Q9NZM1
GSKGYMKVSMFVLGT

MYOF

311

Q9NZM1