Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	transmembrane transporter activity	SLC6A3 GPR89B SLC7A1 SLC7A2 ABCA1 SLC7A3 SLC16A2 SLC22A1 TMEM63B GPR89A SLC37A2 ABCC2 PKD1L3 SLC1A3 SLC5A1 SLC5A2 SLC5A4	1.86e-07	1180	66	17	GO:0022857
GeneOntologyMolecularFunction	solute:sodium symporter activity	SLC6A3 SLC22A1 SLC1A3 SLC5A1 SLC5A2 SLC5A4	2.76e-07	81	66	6	GO:0015370
GeneOntologyMolecularFunction	L-ornithine transmembrane transporter activity	SLC7A1 SLC7A2 SLC7A3	3.43e-07	5	66	3	GO:0000064
GeneOntologyMolecularFunction	transporter activity	SLC6A3 GPR89B SLC7A1 SLC7A2 ABCA1 SLC7A3 SLC16A2 SLC22A1 TMEM63B GPR89A SLC37A2 ABCC2 PKD1L3 SLC1A3 SLC5A1 SLC5A2 SLC5A4	6.46e-07	1289	66	17	GO:0005215
GeneOntologyMolecularFunction	D-glucose:sodium symporter activity	SLC5A1 SLC5A2 SLC5A4	1.20e-06	7	66	3	GO:0005412
GeneOntologyMolecularFunction	solute:monoatomic cation symporter activity	SLC6A3 SLC22A1 SLC1A3 SLC5A1 SLC5A2 SLC5A4	2.68e-06	119	66	6	GO:0015294
GeneOntologyMolecularFunction	L-lysine transmembrane transporter activity	SLC7A1 SLC7A2 SLC7A3	2.86e-06	9	66	3	GO:0015189
GeneOntologyMolecularFunction	active transmembrane transporter activity	SLC6A3 ABCA1 SLC16A2 SLC22A1 SLC37A2 ABCC2 SLC1A3 SLC5A1 SLC5A2 SLC5A4	3.51e-06	477	66	10	GO:0022804
GeneOntologyMolecularFunction	organic anion transmembrane transporter activity	SLC7A1 SLC7A2 SLC7A3 SLC16A2 SLC22A1 SLC37A2 ABCC2 SLC1A3	5.37e-06	293	66	8	GO:0008514
GeneOntologyMolecularFunction	medium-chain fatty acid-CoA ligase activity	ACSM2A ACSS3 ACSM2B	5.58e-06	11	66	3	GO:0031956
GeneOntologyMolecularFunction	secondary active transmembrane transporter activity	SLC6A3 SLC16A2 SLC22A1 SLC37A2 SLC1A3 SLC5A1 SLC5A2 SLC5A4	5.78e-06	296	66	8	GO:0015291
GeneOntologyMolecularFunction	organic cation transmembrane transporter activity	SLC6A3 SLC7A1 SLC7A2 SLC7A3 SLC22A1	8.05e-06	83	66	5	GO:0015101
GeneOntologyMolecularFunction	L-arginine transmembrane transporter activity	SLC7A1 SLC7A2 SLC7A3	9.63e-06	13	66	3	GO:0061459
GeneOntologyMolecularFunction	symporter activity	SLC6A3 SLC22A1 SLC1A3 SLC5A1 SLC5A2 SLC5A4	1.02e-05	150	66	6	GO:0015293
GeneOntologyMolecularFunction	alpha-glucoside transmembrane transporter activity	SLC5A1 SLC5A2	1.08e-05	2	66	2	GO:0015151
GeneOntologyMolecularFunction	sodium ion transmembrane transporter activity	SLC6A3 SLC22A1 SLC1A3 SLC5A1 SLC5A2 SLC5A4	2.15e-05	171	66	6	GO:0015081
GeneOntologyMolecularFunction	carbohydrate:monoatomic cation symporter activity	SLC5A1 SLC5A2 SLC5A4	2.27e-05	17	66	3	GO:0005402
GeneOntologyMolecularFunction	amino acid transmembrane transporter activity	SLC7A1 SLC7A2 SLC7A3 SLC16A2 SLC1A3	2.53e-05	105	66	5	GO:0015171
GeneOntologyMolecularFunction	glucoside transmembrane transporter activity	SLC5A1 SLC5A2	3.22e-05	3	66	2	GO:0042947
GeneOntologyMolecularFunction	benzoate-CoA ligase activity	ACSM2A ACSM2B	3.22e-05	3	66	2	GO:0018858
GeneOntologyMolecularFunction	low-affinity D-glucose:sodium symporter activity	SLC5A2 SLC5A4	3.22e-05	3	66	2	GO:0005362
GeneOntologyMolecularFunction	norepinephrine:sodium symporter activity	SLC6A3 SLC22A1	3.22e-05	3	66	2	GO:0005334
GeneOntologyMolecularFunction	basic amino acid transmembrane transporter activity	SLC7A1 SLC7A2 SLC7A3	3.78e-05	20	66	3	GO:0015174
GeneOntologyMolecularFunction	carbohydrate derivative transmembrane transporter activity	SLC22A1 SLC37A2 SLC5A1 SLC5A2	4.32e-05	59	66	4	GO:1901505
GeneOntologyMolecularFunction	carboxylic acid transmembrane transporter activity	SLC7A1 SLC7A2 SLC7A3 SLC16A2 ABCC2 SLC1A3	6.25e-05	207	66	6	GO:0046943
GeneOntologyMolecularFunction	organic acid transmembrane transporter activity	SLC7A1 SLC7A2 SLC7A3 SLC16A2 ABCC2 SLC1A3	6.42e-05	208	66	6	GO:0005342
GeneOntologyMolecularFunction	phosphorylase kinase activity	PHKA1 PHKG2	6.43e-05	4	66	2	GO:0004689
GeneOntologyMolecularFunction	dopamine:sodium symporter activity	SLC6A3 SLC22A1	6.43e-05	4	66	2	GO:0005330
GeneOntologyMolecularFunction	decanoate-CoA ligase activity	ACSM2A ACSM2B	6.43e-05	4	66	2	GO:0102391
GeneOntologyMolecularFunction	hexose transmembrane transporter activity	SLC5A1 SLC5A2 SLC5A4	7.53e-05	25	66	3	GO:0015149
GeneOntologyMolecularFunction	D-glucose transmembrane transporter activity	SLC5A1 SLC5A2 SLC5A4	7.53e-05	25	66	3	GO:0055056
GeneOntologyMolecularFunction	fatty acid ligase activity	ACSM2A ACSS3 ACSM2B	8.49e-05	26	66	3	GO:0015645
GeneOntologyMolecularFunction	L-amino acid transmembrane transporter activity	SLC7A1 SLC7A2 SLC7A3 SLC1A3	8.95e-05	71	66	4	GO:0015179
GeneOntologyMolecularFunction	CoA-ligase activity	ACSM2A ACSS3 ACSM2B	9.53e-05	27	66	3	GO:0016405
GeneOntologyMolecularFunction	monosaccharide transmembrane transporter activity	SLC5A1 SLC5A2 SLC5A4	9.53e-05	27	66	3	GO:0015145
GeneOntologyMolecularFunction	protein serine/threonine kinase activity	PHKA1 PHKG2 PIK3CA MTOR STK38 AKT2 PRKCQ MAP3K19	1.07e-04	446	66	8	GO:0004674
GeneOntologyMolecularFunction	sugar transmembrane transporter activity	SLC5A1 SLC5A2 SLC5A4	1.19e-04	29	66	3	GO:0051119
GeneOntologyMolecularFunction	acid-thiol ligase activity	ACSM2A ACSS3 ACSM2B	1.45e-04	31	66	3	GO:0016878
GeneOntologyMolecularFunction	inorganic molecular entity transmembrane transporter activity	SLC6A3 SLC22A1 TMEM63B SLC37A2 ABCC2 PKD1L3 SLC1A3 SLC5A1 SLC5A2 SLC5A4	1.80e-04	758	66	10	GO:0015318
GeneOntologyMolecularFunction	monoatomic ion transmembrane transporter activity	SLC6A3 GPR89B SLC22A1 TMEM63B GPR89A PKD1L3 SLC1A3 SLC5A1 SLC5A2 SLC5A4	2.59e-04	793	66	10	GO:0015075
GeneOntologyMolecularFunction	fatty-acyl-CoA synthase activity	ACSM2A ACSM2B	2.97e-04	8	66	2	GO:0004321
GeneOntologyMolecularFunction	ligase activity, forming carbon-sulfur bonds	ACSM2A ACSS3 ACSM2B	3.36e-04	41	66	3	GO:0016877
GeneOntologyMolecularFunction	carbohydrate transmembrane transporter activity	SLC5A1 SLC5A2 SLC5A4	3.61e-04	42	66	3	GO:0015144
GeneOntologyMolecularFunction	active monoatomic ion transmembrane transporter activity	SLC6A3 SLC22A1 SLC1A3 SLC5A1 SLC5A2 SLC5A4	4.75e-04	301	66	6	GO:0022853
GeneOntologyMolecularFunction	monoamine transmembrane transporter activity	SLC6A3 SLC22A1	6.95e-04	12	66	2	GO:0008504
GeneOntologyMolecularFunction	protein kinase activity	PHKA1 PHKG2 PIK3CA MTOR STK38 AKT2 PRKCQ MAP3K19	7.86e-04	600	66	8	GO:0004672
GeneOntologyMolecularFunction	metal ion transmembrane transporter activity	SLC6A3 SLC22A1 PKD1L3 SLC1A3 SLC5A1 SLC5A2 SLC5A4	8.45e-04	465	66	7	GO:0046873
GeneOntologyMolecularFunction	azole transmembrane transporter activity	SLC7A1 SLC22A1	9.54e-04	14	66	2	GO:1901474
GeneOntologyMolecularFunction	inorganic cation transmembrane transporter activity	SLC6A3 SLC22A1 TMEM63B PKD1L3 SLC1A3 SLC5A1 SLC5A2 SLC5A4	1.04e-03	627	66	8	GO:0022890
GeneOntologyMolecularFunction	protein serine kinase activity	PIK3CA MTOR STK38 AKT2 PRKCQ MAP3K19	1.26e-03	363	66	6	GO:0106310
GeneOntologyMolecularFunction	sodium:chloride symporter activity	SLC6A3 SLC22A1	1.42e-03	17	66	2	GO:0015378
GeneOntologyMolecularFunction	voltage-gated monoatomic anion channel activity	GPR89B GPR89A	1.42e-03	17	66	2	GO:0008308
GeneOntologyMolecularFunction	monoatomic cation transmembrane transporter activity	SLC6A3 SLC22A1 TMEM63B PKD1L3 SLC1A3 SLC5A1 SLC5A2 SLC5A4	1.50e-03	664	66	8	GO:0008324
GeneOntologyMolecularFunction	monoatomic anion transmembrane transporter activity	SLC6A3 GPR89B SLC22A1 GPR89A	1.57e-03	151	66	4	GO:0008509
GeneOntologyMolecularFunction	organic hydroxy compound transmembrane transporter activity	SLC6A3 SLC22A1 SLC5A1	1.61e-03	70	66	3	GO:1901618
GeneOntologyMolecularFunction	monoatomic anion:sodium symporter activity	SLC6A3 SLC22A1	1.77e-03	19	66	2	GO:0015373
GeneOntologyMolecularFunction	C-acyltransferase activity	ACSM2A ACSM2B	2.17e-03	21	66	2	GO:0016408
GeneOntologyMolecularFunction	neurotransmitter transmembrane transporter activity	SLC6A3 SLC22A1	2.17e-03	21	66	2	GO:0005326
GeneOntologyMolecularFunction	phosphotransferase activity, alcohol group as acceptor	PHKA1 PHKG2 PIK3CA MTOR STK38 AKT2 PRKCQ MAP3K19	2.27e-03	709	66	8	GO:0016773
GeneOntologyMolecularFunction	inorganic anion transmembrane transporter activity	SLC6A3 SLC22A1 SLC37A2 ABCC2	2.48e-03	171	66	4	GO:0015103
GeneOntologyMolecularFunction	chloride:monoatomic cation symporter activity	SLC6A3 SLC22A1	2.60e-03	23	66	2	GO:0015377
GeneOntologyMolecularFunction	olfactory receptor activity	OR2T8 OR52I1 OR8B4 OR13C9 OR13C5 OR13C2	2.98e-03	431	66	6	GO:0004984
GeneOntologyMolecularFunction	monoatomic anion:monoatomic cation symporter activity	SLC6A3 SLC22A1	3.32e-03	26	66	2	GO:0015296
GeneOntologyMolecularFunction	calcium/calmodulin-dependent protein kinase activity	PHKA1 PHKG2	3.58e-03	27	66	2	GO:0004683
GeneOntologyMolecularFunction	kinase activity	PHKA1 PHKG2 PIK3CA MTOR STK38 AKT2 PRKCQ MAP3K19	3.58e-03	764	66	8	GO:0016301
GeneOntologyMolecularFunction	xenobiotic transmembrane transporter activity	SLC22A1 ABCC2	5.64e-03	34	66	2	GO:0042910
GeneOntologyMolecularFunction	ABC-type transporter activity	ABCA1 ABCC2	1.14e-02	49	66	2	GO:0140359
GeneOntologyMolecularFunction	transferase activity, transferring phosphorus-containing groups	PHKA1 PHKG2 PIK3CA MTOR STK38 AKT2 PRKCQ MAP3K19	1.19e-02	938	66	8	GO:0016772
GeneOntologyMolecularFunction	transmembrane signaling receptor activity	OR2T8 HCAR2 OR52I1 ABCA1 OR8B4 OR13C9 OR13C5 OR13C2 TMEM63B PKD1L3	1.29e-02	1353	66	10	GO:0004888
GeneOntologyBiologicalProcess	transport across blood-brain barrier	SLC7A1 SLC7A2 SLC7A3 SLC16A2 SLC22A1 ABCC2 SLC1A3 SLC5A1	2.99e-10	87	65	8	GO:0150104
GeneOntologyBiologicalProcess	vascular transport	SLC7A1 SLC7A2 SLC7A3 SLC16A2 SLC22A1 ABCC2 SLC1A3 SLC5A1	3.28e-10	88	65	8	GO:0010232
GeneOntologyBiologicalProcess	regulation of glycogen metabolic process	ADCY10 PHKA1 PHKG2 MTOR AKT2	4.55e-07	49	65	5	GO:0070873
GeneOntologyBiologicalProcess	positive regulation of glycogen catabolic process	ADCY10 PHKA1 PHKG2	5.93e-07	6	65	3	GO:0045819
GeneOntologyBiologicalProcess	L-ornithine transmembrane transport	SLC7A1 SLC7A2 SLC7A3	5.93e-07	6	65	3	GO:1903352
GeneOntologyBiologicalProcess	import across plasma membrane	SLC7A1 SLC7A2 SLC7A3 SLC16A2 AKT2 SLC1A3 SLC5A1 SLC5A2	6.18e-07	230	65	8	GO:0098739
GeneOntologyBiologicalProcess	positive regulation of glycogen metabolic process	ADCY10 PHKA1 PHKG2 AKT2	9.10e-07	24	65	4	GO:0070875
GeneOntologyBiologicalProcess	ornithine transport	SLC7A1 SLC7A2 SLC7A3	1.04e-06	7	65	3	GO:0015822
GeneOntologyBiologicalProcess	amino acid import across plasma membrane	SLC7A1 SLC7A2 SLC7A3 SLC16A2 SLC1A3	1.07e-06	58	65	5	GO:0089718
GeneOntologyBiologicalProcess	regulation of polysaccharide metabolic process	ADCY10 PHKA1 PHKG2 MTOR AKT2	1.07e-06	58	65	5	GO:0032881
GeneOntologyBiologicalProcess	chemical homeostasis	GPR89B ABCA1 ADIPOR1 PIK3CA CCDC47 SCD TBC1D1 SURF4 DIAPH1 TMEM63B GPR89A CDH23 TMTC2 ABCC2 ACSM2A SLC1A3	1.15e-06	1249	65	16	GO:0048878
GeneOntologyBiologicalProcess	L-arginine import across plasma membrane	SLC7A1 SLC7A2 SLC7A3	1.65e-06	8	65	3	GO:0097638
GeneOntologyBiologicalProcess	L-lysine transmembrane transport	SLC7A1 SLC7A2 SLC7A3	3.53e-06	10	65	3	GO:1903401
GeneOntologyBiologicalProcess	L-lysine transport	SLC7A1 SLC7A2 SLC7A3	3.53e-06	10	65	3	GO:1902022
GeneOntologyBiologicalProcess	organic anion transport	ADCY10 SLC7A1 SLC7A2 SLC7A3 SLC16A2 SLC22A1 SLC37A2 AKT2 ABCC2 SLC1A3	4.51e-06	515	65	10	GO:0015711
GeneOntologyBiologicalProcess	import into cell	SLC6A3 SLC7A1 SLC7A2 ABCA1 SLC7A3 SLC16A2 PIK3CA SLC22A1 LRRTM2 DIAPH1 AKT2 SLC1A3 SLC5A1 SLC5A2	5.00e-06	1074	65	14	GO:0098657
GeneOntologyBiologicalProcess	monoatomic anion transmembrane transport	GPR89B MTOR GPR89A ABCC2 SLC1A3 SLC5A1	8.69e-06	153	65	6	GO:0098656
GeneOntologyBiologicalProcess	alpha-glucoside transport	SLC5A1 SLC5A2	9.78e-06	2	65	2	GO:0000017
GeneOntologyBiologicalProcess	regulation of glycogen catabolic process	ADCY10 PHKA1 PHKG2	1.06e-05	14	65	3	GO:0005981
GeneOntologyBiologicalProcess	vascular process in circulatory system	SLC7A1 SLC7A2 SLC7A3 SLC16A2 SLC22A1 ABCC2 SLC1A3 SLC5A1	1.22e-05	344	65	8	GO:0003018
GeneOntologyBiologicalProcess	L-arginine transmembrane transport	SLC7A1 SLC7A2 SLC7A3	1.32e-05	15	65	3	GO:1903826
GeneOntologyBiologicalProcess	glycogen metabolic process	ADCY10 PHKA1 PHKG2 MTOR AKT2	1.51e-05	99	65	5	GO:0005977
GeneOntologyBiologicalProcess	regulation of generation of precursor metabolites and energy	ADCY10 PHKA1 PHKG2 PIK3CA MTOR AKT2	1.53e-05	169	65	6	GO:0043467
GeneOntologyBiologicalProcess	circulatory system process	ADCY10 SLC7A1 SLC7A2 SLC7A3 SLC16A2 PIK3CA MTOR SLC22A1 ABCC2 SLC1A3 SLC5A1	1.65e-05	733	65	11	GO:0003013
GeneOntologyBiologicalProcess	glucan metabolic process	ADCY10 PHKA1 PHKG2 MTOR AKT2	1.67e-05	101	65	5	GO:0044042
GeneOntologyBiologicalProcess	monoatomic ion transport	SLC6A3 GPR89B MTOR SLC22A1 DIAPH1 TMEM63B GPR89A CDH23 AKT2 ABCC2 PKD1L3 SLC1A3 SLC5A1 SLC5A2 SLC5A4	1.83e-05	1374	65	15	GO:0006811
GeneOntologyBiologicalProcess	positive regulation of carbohydrate metabolic process	ADCY10 PHKA1 PHKG2 MTOR AKT2	2.01e-05	105	65	5	GO:0045913
GeneOntologyBiologicalProcess	monoatomic anion transport	GPR89B MTOR GPR89A ABCC2 SLC1A3 SLC5A1	2.40e-05	183	65	6	GO:0006820
GeneOntologyBiologicalProcess	energy derivation by oxidation of organic compounds	ADCY10 PHKA1 PHKG2 PIK3CA MTOR SLC37A2 AKT2 SLC1A3	2.73e-05	385	65	8	GO:0015980
GeneOntologyBiologicalProcess	basic amino acid transmembrane transport	SLC7A1 SLC7A2 SLC7A3	2.79e-05	19	65	3	GO:1990822
GeneOntologyBiologicalProcess	glucoside transport	SLC5A1 SLC5A2	2.93e-05	3	65	2	GO:0042946
GeneOntologyBiologicalProcess	lysine transport	SLC7A1 SLC7A3	2.93e-05	3	65	2	GO:0015819
GeneOntologyBiologicalProcess	energy reserve metabolic process	ADCY10 PHKA1 PHKG2 MTOR AKT2	2.99e-05	114	65	5	GO:0006112
GeneOntologyBiologicalProcess	amino acid transport	SLC6A3 SLC7A1 SLC7A2 SLC7A3 SLC16A2 SLC1A3	3.44e-05	195	65	6	GO:0006865
GeneOntologyBiologicalProcess	monoatomic ion transmembrane transport	SLC6A3 GPR89B MTOR SLC22A1 DIAPH1 TMEM63B GPR89A ABCC2 PKD1L3 SLC1A3 SLC5A1 SLC5A2 SLC5A4	3.73e-05	1115	65	13	GO:0034220
GeneOntologyBiologicalProcess	amino acid transmembrane transport	SLC7A1 SLC7A2 SLC7A3 SLC16A2 SLC1A3	3.83e-05	120	65	5	GO:0003333
GeneOntologyBiologicalProcess	generation of precursor metabolites and energy	ADCY10 PHKA1 PHKG2 PIK3CA MTOR SLC37A2 AKT2 SLC1A3 ACSS3	4.00e-05	529	65	9	GO:0006091
GeneOntologyBiologicalProcess	carboxylic acid transport	SLC7A1 SLC7A2 SLC7A3 SLC16A2 SLC22A1 AKT2 ABCC2 SLC1A3	4.27e-05	410	65	8	GO:0046942
GeneOntologyBiologicalProcess	basic amino acid transport	SLC7A1 SLC7A2 SLC7A3	4.41e-05	22	65	3	GO:0015802
GeneOntologyBiologicalProcess	organic acid transport	SLC7A1 SLC7A2 SLC7A3 SLC16A2 SLC22A1 AKT2 ABCC2 SLC1A3	4.42e-05	412	65	8	GO:0015849
GeneOntologyBiologicalProcess	polysaccharide metabolic process	ADCY10 PHKA1 PHKG2 MTOR AKT2	4.84e-05	126	65	5	GO:0005976
GeneOntologyBiologicalProcess	positive regulation of glucose metabolic process	ADCY10 PHKA1 PHKG2 AKT2	4.95e-05	64	65	4	GO:0010907
GeneOntologyBiologicalProcess	neuron projection retraction	ADCY10 DIAPH1	5.84e-05	4	65	2	GO:0106028
GeneOntologyBiologicalProcess	renal D-glucose absorption	SLC5A1 SLC5A2	5.84e-05	4	65	2	GO:0035623
GeneOntologyBiologicalProcess	regulation of glucose metabolic process	ADCY10 PHKA1 PHKG2 ADIPOR1 AKT2	6.49e-05	134	65	5	GO:0010906
GeneOntologyBiologicalProcess	regulation of carbohydrate metabolic process	ADCY10 PHKA1 PHKG2 ADIPOR1 MTOR AKT2	8.80e-05	231	65	6	GO:0006109
GeneOntologyBiologicalProcess	organic cation transport	SLC6A3 SLC7A1 SLC7A2 SLC7A3 SLC22A1	9.43e-05	145	65	5	GO:0015695
GeneOntologyBiologicalProcess	D-glucose import across plasma membrane	SLC5A1 SLC5A2	9.72e-05	5	65	2	GO:0098708
GeneOntologyBiologicalProcess	glycoside transport	SLC5A1 SLC5A2	9.72e-05	5	65	2	GO:1901656
GeneOntologyBiologicalProcess	sensory perception	OR2T8 SLC6A3 OR52I1 OR8B4 OR13C9 OR13C5 OR13C2 DIAPH1 TMEM63B CDH23 PKD1L3 SLC1A3	1.14e-04	1072	65	12	GO:0007600
GeneOntologyBiologicalProcess	glucose metabolic process	ADCY10 PHKA1 PHKG2 ADIPOR1 PIK3CA AKT2	1.19e-04	244	65	6	GO:0006006
GeneOntologyBiologicalProcess	regulation of carbohydrate catabolic process	ADCY10 PHKA1 PHKG2 MTOR	1.31e-04	82	65	4	GO:0043470
GeneOntologyBiologicalProcess	carbohydrate import across plasma membrane	SLC5A1 SLC5A2	1.45e-04	6	65	2	GO:0098704
GeneOntologyBiologicalProcess	hexose import across plasma membrane	SLC5A1 SLC5A2	1.45e-04	6	65	2	GO:0140271
GeneOntologyBiologicalProcess	xenobiotic transport across blood-brain barrier	SLC22A1 ABCC2	1.45e-04	6	65	2	GO:1990962
GeneOntologyBiologicalProcess	carboxylic acid transmembrane transport	SLC7A1 SLC7A2 SLC7A3 AKT2 SLC1A3	1.63e-04	163	65	5	GO:1905039
GeneOntologyBiologicalProcess	L-alpha-amino acid transmembrane transport	SLC7A1 SLC7A2 SLC7A3 SLC1A3	1.64e-04	87	65	4	GO:1902475
GeneOntologyBiologicalProcess	glycogen catabolic process	ADCY10 PHKA1 PHKG2	1.82e-04	35	65	3	GO:0005980
GeneOntologyBiologicalProcess	organic acid transmembrane transport	SLC7A1 SLC7A2 SLC7A3 AKT2 SLC1A3	1.83e-04	167	65	5	GO:1903825
GeneOntologyBiologicalProcess	glucan catabolic process	ADCY10 PHKA1 PHKG2	1.98e-04	36	65	3	GO:0009251
GeneOntologyBiologicalProcess	polysaccharide catabolic process	ADCY10 PHKA1 PHKG2	2.33e-04	38	65	3	GO:0000272
GeneOntologyBiologicalProcess	transepithelial transport	ABCC2 SLC1A3 SLC5A1	2.33e-04	38	65	3	GO:0070633
GeneOntologyBiologicalProcess	monoatomic cation transport	SLC6A3 SLC22A1 DIAPH1 TMEM63B CDH23 AKT2 ABCC2 PKD1L3 SLC1A3 SLC5A1 SLC5A2 SLC5A4	2.33e-04	1157	65	12	GO:0006812
GeneOntologyBiologicalProcess	carbohydrate derivative transport	ADCY10 SLC37A2 SLC5A1 SLC5A2	2.40e-04	96	65	4	GO:1901264
GeneOntologyBiologicalProcess	hexose metabolic process	ADCY10 PHKA1 PHKG2 ADIPOR1 PIK3CA AKT2	2.70e-04	284	65	6	GO:0019318
GeneOntologyBiologicalProcess	carbohydrate transport	SLC37A2 AKT2 SLC5A1 SLC5A2 SLC5A4	3.01e-04	186	65	5	GO:0008643
GeneOntologyBiologicalProcess	sensory perception of chemical stimulus	OR2T8 SLC6A3 OR52I1 OR8B4 OR13C9 OR13C5 OR13C2 PKD1L3	3.11e-04	547	65	8	GO:0007606
GeneOntologyBiologicalProcess	norepinephrine uptake	SLC6A3 SLC22A1	3.47e-04	9	65	2	GO:0051620
GeneOntologyBiologicalProcess	positive regulation of small molecule metabolic process	ADCY10 PHKA1 PHKG2 MTOR AKT2	3.49e-04	192	65	5	GO:0062013
GeneOntologyBiologicalProcess	L-amino acid transport	SLC7A1 SLC7A2 SLC7A3 SLC1A3	3.76e-04	108	65	4	GO:0015807
GeneOntologyBiologicalProcess	monosaccharide metabolic process	ADCY10 PHKA1 PHKG2 ADIPOR1 PIK3CA AKT2	4.31e-04	310	65	6	GO:0005996
GeneOntologyBiologicalProcess	monocarboxylic acid metabolic process	ADIPOR1 MTOR SCD PAM AKT2 ABCC2 ACSM2A SLC1A3 ACSM2B	4.55e-04	731	65	9	GO:0032787
GeneOntologyBiologicalProcess	neurotransmitter uptake	SLC6A3 SLC22A1 SLC1A3	5.91e-04	52	65	3	GO:0001504
GeneOntologyBiologicalProcess	fatty acid metabolic process	ADIPOR1 MTOR SCD PAM AKT2 ACSM2A ACSM2B	6.06e-04	461	65	7	GO:0006631
GeneOntologyBiologicalProcess	sensory perception of smell	OR2T8 SLC6A3 OR52I1 OR8B4 OR13C9 OR13C5 OR13C2	6.38e-04	465	65	7	GO:0007608
GeneOntologyBiologicalProcess	monoatomic cation transmembrane transport	SLC6A3 SLC22A1 DIAPH1 TMEM63B ABCC2 PKD1L3 SLC1A3 SLC5A1 SLC5A2 SLC5A4	6.87e-04	942	65	10	GO:0098655
GeneOntologyBiologicalProcess	glucan biosynthetic process	PHKG2 MTOR AKT2	6.97e-04	55	65	3	GO:0009250
GeneOntologyBiologicalProcess	glycogen biosynthetic process	PHKG2 MTOR AKT2	6.97e-04	55	65	3	GO:0005978
GeneOntologyBiologicalProcess	thyroid hormone transport	SLC16A2 ABCC2	7.46e-04	13	65	2	GO:0070327
GeneOntologyBiologicalProcess	detection of chemical stimulus involved in sensory perception	OR2T8 OR52I1 OR8B4 OR13C9 OR13C5 OR13C2 PKD1L3	8.17e-04	485	65	7	GO:0050907
GeneOntologyBiologicalProcess	inorganic anion transmembrane transport	MTOR SLC37A2 SLC1A3 SLC5A1	8.48e-04	134	65	4	GO:0098661
GeneOntologyBiologicalProcess	carbohydrate metabolic process	ADCY10 PHKA1 PHKG2 ADIPOR1 PIK3CA MTOR AKT2 SLC5A2	9.28e-04	646	65	8	GO:0005975
GeneOntologyBiologicalProcess	azole transmembrane transport	SLC7A1 SLC22A1	1.00e-03	15	65	2	GO:0045117
GeneOntologyBiologicalProcess	metal ion transport	SLC6A3 DIAPH1 CDH23 AKT2 ABCC2 PKD1L3 SLC1A3 SLC5A1 SLC5A2 SLC5A4	1.08e-03	1000	65	10	GO:0030001
GeneOntologyBiologicalProcess	response to L-leucine	PIK3CA MTOR	1.14e-03	16	65	2	GO:0043201
GeneOntologyBiologicalProcess	D-glucose transmembrane transport	AKT2 SLC5A1 SLC5A2 SLC5A4	1.23e-03	148	65	4	GO:1904659
GeneOntologyBiologicalProcess	inorganic ion transmembrane transport	SLC6A3 MTOR DIAPH1 SLC37A2 ABCC2 PKD1L3 SLC1A3 SLC5A1 SLC5A2 SLC5A4	1.23e-03	1017	65	10	GO:0098660
GeneOntologyBiologicalProcess	detection of chemical stimulus	OR2T8 OR52I1 OR8B4 OR13C9 OR13C5 OR13C2 PKD1L3	1.28e-03	524	65	7	GO:0009593
GeneOntologyBiologicalProcess	TORC2 signaling	PIK3CA MTOR	1.29e-03	17	65	2	GO:0038203
GeneOntologyBiologicalProcess	response to xenobiotic stimulus	SLC6A3 ABCA1 SLC22A1 PAM ABCC2 SLC1A3 ACSM2B	1.29e-03	525	65	7	GO:0009410
GeneOntologyBiologicalProcess	hexose transmembrane transport	AKT2 SLC5A1 SLC5A2 SLC5A4	1.32e-03	151	65	4	GO:0008645
GeneOntologyBiologicalProcess	monosaccharide transmembrane transport	AKT2 SLC5A1 SLC5A2 SLC5A4	1.42e-03	154	65	4	GO:0015749
GeneOntologyBiologicalProcess	response to cocaine	SLC6A3 MTOR SLC1A3	1.47e-03	71	65	3	GO:0042220
GeneOntologyBiologicalProcess	insulin receptor signaling pathway	ADIPOR1 PIK3CA AKT2 PRKCQ	1.49e-03	156	65	4	GO:0008286
GeneOntologyBiologicalProcess	intracellular chemical homeostasis	GPR89B PIK3CA CCDC47 TBC1D1 DIAPH1 GPR89A CDH23 ABCC2 SLC1A3	1.51e-03	866	65	9	GO:0055082
GeneOntologyBiologicalProcess	cellular response to insulin stimulus	ADIPOR1 PIK3CA MTOR AKT2 PRKCQ	1.64e-03	271	65	5	GO:0032869
GeneOntologyBiologicalProcess	sodium ion transport	SLC6A3 AKT2 SLC5A1 SLC5A2 SLC5A4	1.75e-03	275	65	5	GO:0006814
GeneOntologyBiologicalProcess	polysaccharide biosynthetic process	PHKG2 MTOR AKT2	1.78e-03	76	65	3	GO:0000271
GeneOntologyBiologicalProcess	dopamine uptake	SLC6A3 SLC22A1	1.79e-03	20	65	2	GO:0090494
GeneOntologyBiologicalProcess	monoatomic ion homeostasis	GPR89B CCDC47 DIAPH1 GPR89A CDH23 TMTC2 ABCC2 SLC1A3	1.80e-03	717	65	8	GO:0050801
GeneOntologyCellularComponent	phosphorylase kinase complex	PHKA1 PHKG2	9.17e-05	5	64	2	GO:0005964
GeneOntologyCellularComponent	apical part of cell	ADCY10 SLC7A1 SLC16A2 SLC22A1 CDH23 ABCC2 SLC5A1 SLC5A2	4.33e-04	592	64	8	GO:0045177
GeneOntologyCellularComponent	cluster of actin-based cell projections	DIAPH1 CDH23 ABCC2 SLC5A1 SLC5A2	6.04e-04	223	64	5	GO:0098862
GeneOntologyCellularComponent	apical plasma membrane	ADCY10 SLC7A1 SLC16A2 SLC22A1 ABCC2 SLC5A1 SLC5A2	7.04e-04	487	64	7	GO:0016324
Domain	Cat_AA_permease	SLC7A1 SLC7A2 SLC7A3	3.84e-08	3	64	3	IPR004755
Domain	CAT3	SLC7A1 SLC7A2 SLC7A3	3.82e-07	5	64	3	IPR015606
Domain	AA_permease_C	SLC7A1 SLC7A2 SLC7A3	3.82e-07	5	64	3	PF13906
Domain	CAT_C	SLC7A1 SLC7A2 SLC7A3	3.82e-07	5	64	3	IPR029485
Domain	Na/solute_symporter_CS	SLC5A1 SLC5A2 SLC5A4	2.12e-06	8	64	3	IPR018212
Domain	NA_SOLUT_SYMP_1	SLC5A1 SLC5A2 SLC5A4	6.21e-06	11	64	3	PS00456
Domain	NA_SOLUT_SYMP_2	SLC5A1 SLC5A2 SLC5A4	8.26e-06	12	64	3	PS00457
Domain	SSF	SLC5A1 SLC5A2 SLC5A4	8.26e-06	12	64	3	PF00474
Domain	Na/solute_symporter	SLC5A1 SLC5A2 SLC5A4	8.26e-06	12	64	3	IPR001734
Domain	NA_SOLUT_SYMP_3	SLC5A1 SLC5A2 SLC5A4	8.26e-06	12	64	3	PS50283
Domain	AA_permease_2	SLC7A1 SLC7A2 SLC7A3	1.07e-05	13	64	3	PF13520
Domain	AA/rel_permease1	SLC7A1 SLC7A2 SLC7A3	1.07e-05	13	64	3	IPR002293
Domain	AMP-bd_C	ACSM2A ACSS3 ACSM2B	2.52e-05	17	64	3	IPR025110
Domain	AMP-binding_C	ACSM2A ACSS3 ACSM2B	2.52e-05	17	64	3	PF13193
Domain	AA-permease/SLC12A_dom	SLC7A1 SLC7A2 SLC7A3	5.64e-05	22	64	3	IPR004841
Domain	AA_permease	SLC7A1 SLC7A2 SLC7A3	5.64e-05	22	64	3	PF00324
Domain	AMP-binding_CS	ACSM2A ACSS3 ACSM2B	9.43e-05	26	64	3	IPR020845
Domain	AMP_BINDING	ACSM2A ACSS3 ACSM2B	1.18e-04	28	64	3	PS00455
Domain	AMP-binding	ACSM2A ACSS3 ACSM2B	1.46e-04	30	64	3	PF00501
Domain	AMP-dep_Synth/Lig	ACSM2A ACSS3 ACSM2B	1.46e-04	30	64	3	IPR000873
Domain	ARM-type_fold	PIK3CA MTOR MIF4GD DIAPH1 TRIP12 NCAPG2 SYMPK	1.56e-04	339	64	7	IPR016024
Domain	HELP	EML4 EML1	1.72e-04	6	64	2	PF03451
Domain	HELP	EML4 EML1	1.72e-04	6	64	2	IPR005108
Domain	Pkinase_C	STK38 AKT2 PRKCQ	2.74e-04	37	64	3	IPR017892
Domain	Pkinase_C	STK38 AKT2 PRKCQ	4.00e-04	42	64	3	PF00433
Domain	AGC-kinase_C	STK38 AKT2 PRKCQ	9.34e-04	56	64	3	IPR000961
Domain	AGC_KINASE_CTER	STK38 AKT2 PRKCQ	9.34e-04	56	64	3	PS51285
Domain	S_TK_X	STK38 AKT2 PRKCQ	9.34e-04	56	64	3	SM00133
Domain	HEAT	MTOR NCAPG2 SYMPK	1.04e-03	58	64	3	IPR000357
Domain	PI3/4_kinase_CS	PIK3CA MTOR	1.18e-03	15	64	2	IPR018936
Domain	-	PIK3CA MTOR	1.34e-03	16	64	2	1.10.1070.11
Domain	PI3Kc	PIK3CA MTOR	1.34e-03	16	64	2	SM00146
Domain	PI3/4_kinase_cat_dom	PIK3CA MTOR	1.71e-03	18	64	2	IPR000403
Domain	PI3_PI4_kinase	PIK3CA MTOR	1.71e-03	18	64	2	PF00454
Domain	PI3_4_KINASE_3	PIK3CA MTOR	1.71e-03	18	64	2	PS50290
Domain	PI3_4_KINASE_1	PIK3CA MTOR	1.71e-03	18	64	2	PS00915
Domain	PI3_4_KINASE_2	PIK3CA MTOR	1.71e-03	18	64	2	PS00916
Domain	Olfact_rcpt	OR2T8 OR52I1 OR8B4 OR13C9 OR13C5 OR13C2	2.24e-03	393	64	6	IPR000725
Domain	Kinase-like_dom	PHKG2 PIK3CA MTOR STK38 AKT2 PRKCQ MAP3K19	2.48e-03	542	64	7	IPR011009
Domain	MFS	SLC16A2 SLC22A1 SLC37A2	6.07e-03	108	64	3	PS50850
Domain	-	MTOR TRIP12 NCAPG2 SYMPK	7.07e-03	222	64	4	1.25.10.10
Domain	Ser/Thr_kinase_AS	PHKG2 STK38 AKT2 PRKCQ MAP3K19	7.53e-03	357	64	5	IPR008271
Domain	S_TKc	PHKG2 STK38 AKT2 PRKCQ MAP3K19	7.70e-03	359	64	5	SM00220
Pathway	REACTOME_SLC_MEDIATED_TRANSMEMBRANE_TRANSPORT	SLC6A3 SLC7A1 SLC7A2 SLC7A3 SLC16A2 SLC22A1 SLC1A3 SLC5A1 SLC5A2 SLC5A4	2.47e-08	249	53	10	M5988
Pathway	REACTOME_SLC_MEDIATED_TRANSMEMBRANE_TRANSPORT	SLC6A3 SLC7A1 SLC7A3 SLC16A2 SLC22A1 SLC1A3 SLC5A1 SLC5A2 SLC5A4	2.22e-07	238	53	9	MM15076
Pathway	KEGG_MEDICUS_VARIANT_MUTATION_ACTIVATED_PI3K_TO_PI3K_SIGNALING_PATHWAY	PIK3CA MTOR AKT2	1.74e-06	7	53	3	M47407
Pathway	KEGG_MEDICUS_VARIANT_AMPLIFIED_PDGFR_TO_PI3K_SIGNALING_PATHWAY	PIK3CA MTOR AKT2	2.77e-06	8	53	3	M47399
Pathway	KEGG_MEDICUS_VARIANT_AMPLIFIED_EGFR_TO_PI3K_SIGNALING_PATHWAY	PIK3CA MTOR AKT2	2.77e-06	8	53	3	M47394
Pathway	KEGG_MEDICUS_VARIANT_MUTATION_ACTIVATED_RET_TO_PI3K_SIGNALING_PATHWAY	PIK3CA MTOR AKT2	2.77e-06	8	53	3	M47715
Pathway	KEGG_MEDICUS_VARIANT_AMPLIFIED_FGFR_TO_PI3K_SIGNALING_PATHWAY	PIK3CA MTOR AKT2	4.15e-06	9	53	3	M47397
Pathway	KEGG_MEDICUS_VARIANT_AMPLIFIED_MET_TO_PI3K_SIGNALING_PATHWAY	PIK3CA MTOR AKT2	4.15e-06	9	53	3	M47490
Pathway	KEGG_MEDICUS_REFERENCE_TGFA_EGFR_PI3K_SIGNALING_PATHWAY	PIK3CA MTOR AKT2	4.15e-06	9	53	3	M47481
Pathway	KEGG_MEDICUS_VARIANT_EGFR_OVEREXPRESSION_TO_PI3K_SIGNALING_PATHWAY	PIK3CA MTOR AKT2	5.91e-06	10	53	3	M47400
Pathway	KEGG_MEDICUS_REFERENCE_KITLG_KIT_PI3K_SIGNALING_PATHWAY	PIK3CA MTOR AKT2	8.11e-06	11	53	3	M47403
Pathway	KEGG_MEDICUS_REFERENCE_IGF2_IGF1R_PI3K_SIGNALING_PATHWAY	PIK3CA MTOR AKT2	8.11e-06	11	53	3	M47484
Pathway	KEGG_MEDICUS_REFERENCE_EREG_EGFR_PI3K_SIGNALING_PATHWAY	PIK3CA MTOR AKT2	8.11e-06	11	53	3	M47499
Pathway	KEGG_MEDICUS_ENV_FACTOR_NNK_NNN_TO_PI3K_SIGNALING_PATHWAY_N01339	PIK3CA MTOR AKT2	8.11e-06	11	53	3	M47791
Pathway	KEGG_MEDICUS_REFERENCE_AREG_EGFR_PI3K_SIGNALING_PATHWAY	PIK3CA MTOR AKT2	8.11e-06	11	53	3	M47501
Pathway	KEGG_MEDICUS_VARIANT_ERBB2_OVEREXPRESSION_TO_PI3K_SIGNALING_PATHWAY	PIK3CA MTOR AKT2	1.08e-05	12	53	3	M47393
Pathway	REACTOME_TRANSPORT_OF_SMALL_MOLECULES	SLC6A3 SLC7A1 SLC7A2 ABCA1 SLC7A3 SLC16A2 SLC22A1 ABCC2 SLC1A3 SLC5A1 SLC5A2 SLC5A4	1.38e-05	736	53	12	M27287
Pathway	KEGG_MEDICUS_REFERENCE_PDGF_PDGFR_PI3K_SIGNALING_PATHWAY	PIK3CA MTOR AKT2	1.40e-05	13	53	3	M47398
Pathway	KEGG_MEDICUS_REFERENCE_IGF_IGF1R_PI3K_SIGNALING_PATHWAY	PIK3CA MTOR AKT2	1.40e-05	13	53	3	M47603
Pathway	KEGG_MEDICUS_REFERENCE_RELN_VLDLR_PI3K_SIGNALING_PATHWAY	PIK3CA MTOR AKT2	2.21e-05	15	53	3	M47663
Pathway	KEGG_MEDICUS_REFERENCE_FLT3LG_FLT3_RAS_PI3K_SIGNALING_PATHWAY	PIK3CA MTOR AKT2	2.21e-05	15	53	3	M47475
Pathway	WP_RIOK1_AND_RIOK2_IN_EGFR_AND_PI3KMEDIATED_TUMORIGENESIS	PIK3CA MTOR AKT2	2.21e-05	15	53	3	M48306
Pathway	REACTOME_TRANSPORT_OF_SMALL_MOLECULES	SLC6A3 SLC7A1 ABCA1 SLC7A3 SLC16A2 SLC22A1 ABCC2 SLC1A3 SLC5A1 SLC5A2 SLC5A4	3.67e-05	681	53	11	MM14985
Pathway	WP_SREBF_AND_MIR33_IN_CHOLESTEROL_AND_LIPID_HOMEOSTASIS	ABCA1 MTOR SCD	3.93e-05	18	53	3	M39679
Pathway	REACTOME_CELLULAR_HEXOSE_TRANSPORT	SLC5A1 SLC5A2 SLC5A4	4.66e-05	19	53	3	MM14718
Pathway	REACTOME_DISORDERS_OF_TRANSMEMBRANE_TRANSPORTERS	SLC6A3 ABCA1 ABCC2 SLC1A3 SLC5A1 SLC5A2	5.07e-05	177	53	6	M27476
Pathway	REACTOME_CELLULAR_HEXOSE_TRANSPORT	SLC5A1 SLC5A2 SLC5A4	6.36e-05	21	53	3	M27058
Pathway	REACTOME_CD28_DEPENDENT_PI3K_AKT_SIGNALING	PIK3CA MTOR AKT2	7.35e-05	22	53	3	M13897
Pathway	REACTOME_CD28_DEPENDENT_PI3K_AKT_SIGNALING	PIK3CA MTOR AKT2	8.43e-05	23	53	3	MM14993
Pathway	KEGG_ADIPOCYTOKINE_SIGNALING_PATHWAY	ADIPOR1 MTOR AKT2 PRKCQ	1.15e-04	67	53	4	M10462
Pathway	WP_AMPACTIVATED_PROTEIN_KINASE_SIGNALING	ADIPOR1 PIK3CA MTOR AKT2	1.15e-04	67	53	4	M39630
Pathway	WP_ANGIOPOIETINLIKE_PROTEIN_8_REGULATORY_PATHWAY	SLC16A2 PIK3CA MTOR SCD AKT2	1.34e-04	132	53	5	M39338
Pathway	KEGG_INSULIN_SIGNALING_PATHWAY	PHKA1 PHKG2 PIK3CA MTOR AKT2	1.59e-04	137	53	5	M18155
Pathway	WP_NRF2_PATHWAY	SLC6A3 ABCC2 SLC5A1 SLC5A2 SLC5A4	1.82e-04	141	53	5	M39454
Pathway	WP_NUCLEAR_RECEPTORS_IN_LIPID_METABOLISM_AND_TOXICITY	ABCA1 RARG ABCC2	1.90e-04	30	53	3	MM15866
Pathway	REACTOME_CONJUGATION_OF_SALICYLATE_WITH_GLYCINE	ACSM2A ACSM2B	2.06e-04	6	53	2	MM14693
Pathway	KEGG_MEDICUS_REFERENCE_FGF_FGFR_PI3K_SIGNALING_PATHWAY	PIK3CA MTOR AKT2	2.09e-04	31	53	3	M47396
Pathway	BIOCARTA_NUCLEARRS_PATHWAY	ABCA1 RARG ABCC2	2.53e-04	33	53	3	MM1448
Pathway	REACTOME_AMINO_ACID_TRANSPORT_ACROSS_THE_PLASMA_MEMBRANE	SLC7A1 SLC7A2 SLC7A3	2.53e-04	33	53	3	M188
Pathway	REACTOME_CD28_CO_STIMULATION	PIK3CA MTOR AKT2	2.53e-04	33	53	3	M11725
Pathway	BIOCARTA_NUCLEARRS_PATHWAY	ABCA1 RARG ABCC2	2.77e-04	34	53	3	M16393
Pathway	REACTOME_CD28_CO_STIMULATION	PIK3CA MTOR AKT2	2.77e-04	34	53	3	MM14992
Pathway	KEGG_MEDICUS_REFERENCE_ACH_CHRN_PI3K_SIGNALING_PATHWAY	PIK3CA AKT2	2.88e-04	7	53	2	M47790
Pathway	REACTOME_AMINO_ACID_CONJUGATION	ACSM2A ACSM2B	2.88e-04	7	53	2	MM14598
Pathway	WP_NUCLEAR_RECEPTORS_IN_LIPID_METABOLISM_AND_TOXICITY	ABCA1 RARG ABCC2	3.02e-04	35	53	3	M39488
Pathway	WP_INSULIN_SIGNALING_IN_ADIPOCYTES_DIABETIC_CONDITION	MTOR AKT2	3.83e-04	8	53	2	M39537
Pathway	KEGG_MEDICUS_VARIANT_MUTATION_ACTIVATED_EGFR_TO_PI3K_SIGNALING_PATHWAY	PIK3CA AKT2	3.83e-04	8	53	2	M47395
Pathway	KEGG_MEDICUS_VARIANT_MUTATION_ACTIVATED_KIT_TO_PI3K_SIGNALING_PATHWAY	PIK3CA AKT2	3.83e-04	8	53	2	M47404
Pathway	KEGG_MEDICUS_VARIANT_EML4_ALK_FUSION_KINASE_TO_PI3K_SIGNALING_PATHWAY	PIK3CA AKT2	3.83e-04	8	53	2	M47405
Pathway	KEGG_MEDICUS_REFERENCE_P4_PR_PI3K_SIGNALING_PATHWAY	PIK3CA AKT2	3.83e-04	8	53	2	M47803
Pathway	WP_INSULIN_SIGNALING_IN_ADIPOCYTES_NORMAL_CONDITION	MTOR AKT2	3.83e-04	8	53	2	M39447
Pathway	KEGG_MEDICUS_VARIANT_TGFA_OVEREXPRESSION_TO_PI3K_SIGNALING_PATHWAY	PIK3CA AKT2	3.83e-04	8	53	2	M47482
Pathway	KEGG_MEDICUS_VARIANT_EGF_OVEREXPRESSION_TO_PI3K_SIGNALING_PATHWAY	PIK3CA AKT2	3.83e-04	8	53	2	M47498
Pathway	REACTOME_NEUROTRANSMITTER_CLEARANCE	SLC6A3 SLC22A1	3.83e-04	8	53	2	MM14500
Pathway	WP_KISSPEPTINKISSPEPTIN_RECEPTOR_SYSTEM_IN_THE_OVARY	PIK3CA AKT2 PRKCQ	4.17e-04	39	53	3	M39905
Pathway	KEGG_MEDICUS_REFERENCE_EGF_EGFR_PI3K_SIGNALING_PATHWAY	PIK3CA AKT2	4.91e-04	9	53	2	M47392
Pathway	KEGG_MEDICUS_VARIANT_MUTATION_ACTIVATED_KRAS_NRAS_TO_PI3K_SIGNALING_PATHWAY	PIK3CA AKT2	4.91e-04	9	53	2	M47391
Pathway	KEGG_MEDICUS_VARIANT_MUTATION_ACTIVATED_MET_TO_PI3K_SIGNALING_PATHWAY	PIK3CA AKT2	4.91e-04	9	53	2	M47402
Pathway	KEGG_MEDICUS_REFERENCE_MEMBRANE_INITIATED_PROGESTERONE_SIGNALING_PATHWAY	PIK3CA AKT2	4.91e-04	9	53	2	M47802
Pathway	REACTOME_AMINO_ACID_CONJUGATION	ACSM2A ACSM2B	4.91e-04	9	53	2	M26968
Pathway	REACTOME_SLC_TRANSPORTER_DISORDERS	SLC6A3 SLC1A3 SLC5A1 SLC5A2	5.15e-04	99	53	4	M27474
Pathway	REACTOME_ASPIRIN_ADME	ABCC2 ACSM2A ACSM2B	5.96e-04	44	53	3	M45014
Pathway	REACTOME_SIGNALING_BY_ERBB2	PIK3CA DIAPH1 AKT2	5.96e-04	44	53	3	MM14520
Pathway	KEGG_MEDICUS_REFERENCE_HGF_MET_PI3K_SIGNALING_PATHWAY	PIK3CA AKT2	6.12e-04	10	53	2	M47401
Pathway	KEGG_MEDICUS_REFERENCE_CD80_CD86_CD28_PI3K_SIGNALING_PATHWAY	PIK3CA AKT2	6.12e-04	10	53	2	M47615
Pathway	REACTOME_ASPIRIN_ADME	ABCC2 ACSM2A ACSM2B	6.37e-04	45	53	3	MM15694
Pathway	WP_TRANSLATION_INHIBITORS_IN_CHRONICALLY_ACTIVATED_PDGFRA_CELLS	PIK3CA MTOR AKT2	6.80e-04	46	53	3	M39805
Pathway	REACTOME_TRANSPORT_OF_INORGANIC_CATIONS_ANIONS_AND_AMINO_ACIDS_OLIGOPEPTIDES	SLC7A1 SLC7A2 SLC7A3 SLC1A3	7.15e-04	108	53	4	M823
Pathway	REACTOME_DRUG_ADME	SLC22A1 ABCC2 ACSM2A ACSM2B	7.40e-04	109	53	4	M45012
Pathway	KEGG_MEDICUS_ENV_FACTOR_NICOTINE_NNK_TO_PI3K_SIGNALING_PATHWAY	PIK3CA AKT2	7.46e-04	11	53	2	M47797
Pathway	KEGG_MEDICUS_VARIANT_BCR_ABL_FUSION_KINASE_TO_PI3K_SIGNALING_PATHWAY	PIK3CA AKT2	7.46e-04	11	53	2	M47406
Pathway	REACTOME_NEUROTRANSMITTER_CLEARANCE	SLC6A3 SLC22A1	7.46e-04	11	53	2	M26914
Pathway	KEGG_MEDICUS_REFERENCE_NRG_ERBB4_PI3K_SIGNALING_PATHWAY	PIK3CA AKT2	7.46e-04	11	53	2	M47756
Pathway	REACTOME_SIGNALING_BY_ERBB2	PIK3CA DIAPH1 AKT2	8.68e-04	50	53	3	M553
Pathway	WP_SYNAPTIC_SIGNALING_ASSOCIATED_WITH_AUTISM_SPECTRUM_DISORDER	PIK3CA MTOR AKT2	8.68e-04	50	53	3	M39822
Pathway	KEGG_MEDICUS_ENV_FACTOR_NNK_NNN_TO_PI3K_SIGNALING_PATHWAY_N01350	PIK3CA AKT2	8.94e-04	12	53	2	M47798
Pathway	KEGG_MEDICUS_REFERENCE_CXCR4_GNAI_PI3K_BAD_SIGNALING_PATHWAY	PIK3CA AKT2	8.94e-04	12	53	2	M47558
Pathway	KEGG_MEDICUS_PATHOGEN_HIV_GP120_TO_CXCR4_GNAI_PI3K_BAD_SIGNALING_PATHWAY	PIK3CA AKT2	8.94e-04	12	53	2	M47559
Pathway	WP_RESOLVIN_E1_AND_RESOLVIN_D1_SIGNALING_DECREASE_INFLAMMATION	PIK3CA MTOR	8.94e-04	12	53	2	M45559
Pathway	KEGG_MTOR_SIGNALING_PATHWAY	PIK3CA MTOR AKT2	9.74e-04	52	53	3	M7561
Pathway	WP_EFFECT_OF_OMEGA3_PUFA_ON_HUNTINGTONS_DISEASE_PATHWAYS	ABCA1 PIK3CA MTOR AKT2	1.03e-03	119	53	4	M48309
Pathway	REACTOME_DRUG_ADME	SLC22A1 ABCC2 ACSM2A ACSM2B	1.03e-03	119	53	4	MM15692
Pathway	WP_NUCLEAR_RECEPTORS_METAPATHWAY	SLC6A3 SCD ABCC2 SLC5A1 SLC5A2 SLC5A4	1.11e-03	314	53	6	M39428
Pathway	KEGG_MEDICUS_VARIANT_DUPLICATION_OR_MUTATION_ACTIVATED_FLT3_TO_RAS_PI3K_SIGNALING_PATHWAY	PIK3CA AKT2	1.23e-03	14	53	2	M47390
Pathway	REACTOME_GLYCOGEN_BREAKDOWN_GLYCOGENOLYSIS	PHKA1 PHKG2	1.23e-03	14	53	2	M19193
Pathway	REACTOME_GLYCOGEN_BREAKDOWN_GLYCOGENOLYSIS	PHKA1 PHKG2	1.23e-03	14	53	2	MM15391
Pathway	KEGG_MEDICUS_REFERENCE_IGF_IGFR_PI3K_NFKB_SIGNALING_PATHWAY	PIK3CA AKT2	1.23e-03	14	53	2	M47467
Pathway	KEGG_MEDICUS_REFERENCE_EGF_EGFR_PI3K_NFKB_SIGNALING_PATHWAY	PIK3CA AKT2	1.23e-03	14	53	2	M47536
Pathway	WP_MODULATION_OF_PI3KAKTMTOR_SIGNALING_BY_BIOACTIVE_SPHINGOLIPIDS	PIK3CA MTOR	1.23e-03	14	53	2	M45553
Pathway	KEGG_ACUTE_MYELOID_LEUKEMIA	PIK3CA MTOR AKT2	1.27e-03	57	53	3	M19888
Pathway	WP_PROXIMAL_TUBULE_TRANSPORT	ABCC2 SLC5A1 SLC5A2	1.27e-03	57	53	3	M39812
Pathway	KEGG_MEDICUS_REFERENCE_EGF_EGFR_RAS_PI3K_SIGNALING_PATHWAY	PIK3CA AKT2	1.41e-03	15	53	2	M47389
Pathway	BIOCARTA_BCELLSURVIVAL_PATHWAY	PIK3CA MTOR	1.41e-03	15	53	2	M4835
Pathway	BIOCARTA_BCELLSURVIVAL_PATHWAY	PIK3CA MTOR	1.82e-03	17	53	2	MM1353
Pathway	SA_PTEN_PATHWAY	PIK3CA AKT2	1.82e-03	17	53	2	M12771
Pathway	SA_TRKA_RECEPTOR	PIK3CA AKT2	1.82e-03	17	53	2	M18895
Pathway	KEGG_GLIOMA	PIK3CA MTOR AKT2	1.86e-03	65	53	3	M1835
Pathway	REACTOME_COSTIMULATION_BY_THE_CD28_FAMILY	PIK3CA MTOR AKT2	1.94e-03	66	53	3	MM14990
Pathway	SIG_PIP3_SIGNALING_IN_CARDIAC_MYOCTES	PIK3CA MTOR AKT2	2.03e-03	67	53	3	M295
Pathway	REACTOME_GLYCOGEN_METABOLISM	PHKA1 PHKG2	2.04e-03	18	53	2	MM15577
Pubmed	Establishment and Dysfunction of the Blood-Brain Barrier.	SLC7A1 SLC7A3 SLC16A2 SLC22A1 ABCC2 SLC1A3 SLC5A1	7.98e-12	52	66	7	26590417
Pubmed	Blood-Brain Barrier: From Physiology to Disease and Back.	SLC7A1 SLC7A2 SLC7A3 SLC16A2 SLC22A1 ABCC2 SLC1A3 SLC5A1	2.61e-11	105	66	8	30280653
Pubmed	Differential regulation of mouse kidney sodium-dependent transporters mRNA by cadmium.	SLC5A1 SLC5A2 SLC5A4	6.53e-09	3	66	3	11749115
Pubmed	Differential topochemistry of three cationic amino acid transporter proteins, hCAT1, hCAT2 and hCAT3, in the adult human brain.	SLC7A1 SLC7A2 SLC7A3	6.53e-09	3	66	3	22870827
Pubmed	A new member of the cationic amino acid transporter family is preferentially expressed in adult mouse brain.	SLC7A1 SLC7A2 SLC7A3	6.53e-09	3	66	3	9334265
Pubmed	Feedbacks and adaptive capabilities of the PI3K/Akt/mTOR axis in acute myeloid leukemia revealed by pathway selective inhibition and phosphoproteome analysis.	PIK3CA MTOR AKT2	2.61e-08	4	66	3	24699302
Pubmed	Genetic variations in the PI3K/PTEN/AKT/mTOR pathway are associated with clinical outcomes in esophageal cancer patients treated with chemoradiotherapy.	PIK3CA MTOR AKT2	6.51e-08	5	66	3	19164214
Pubmed	PI3K/PTEN/AKT/mTOR pathway genetic variation predicts toxicity and distant progression in lung cancer patients receiving platinum-based chemotherapy.	PIK3CA MTOR AKT2	6.51e-08	5	66	3	20447721
Pubmed	HIV-1 Nef and KSHV oncogene K1 synergistically promote angiogenesis by inducing cellular miR-718 to regulate the PTEN/AKT/mTOR signaling pathway.	PIK3CA MTOR AKT2	1.07e-06	11	66	3	25104021
Pubmed	Organization and evolutionary relatedness of OR37 olfactory receptor genes in mouse and human.	OR13C9 OR13C5 OR13C2	1.42e-06	12	66	3	12906860
Pubmed	Disruption of the AMPK-TBC1D1 nexus increases lipogenic gene expression and causes obesity in mice via promoting IGF1 secretion.	MTOR SCD TBC1D1	1.42e-06	12	66	3	27307439
Pubmed	LXR-mediated activation of macrophage stearoyl-CoA desaturase generates unsaturated fatty acids that destabilize ABCA1.	ABCA1 SCD	3.55e-06	2	66	2	14967823
Pubmed	Differential effects of inhibitors of the PI3K/mTOR pathway on the expansion and functionality of regulatory T cells.	PIK3CA MTOR	3.55e-06	2	66	2	27189717
Pubmed	Occurrence of low frequency PIK3CA and AKT2 mutations in gastric cancer.	PIK3CA AKT2	3.55e-06	2	66	2	25771729
Pubmed	Phosphatidylinositol-3-kinase regulates PKCtheta activity in cytotoxic T cells.	PIK3CA PRKCQ	3.55e-06	2	66	2	15829307
Pubmed	Helicobacter pylori promotes eukaryotic protein translation by activating phosphatidylinositol 3 kinase/mTOR.	PIK3CA MTOR	3.55e-06	2	66	2	25194338
Pubmed	GPHR-dependent functions of the Golgi apparatus are essential for the formation of lamellar granules and the skin barrier.	GPR89B GPR89A	3.55e-06	2	66	2	22572823
Pubmed	The prognostic biomarker L-homoarginine is a substrate of the cationic amino acid transporters CAT1, CAT2A and CAT2B.	SLC7A1 SLC7A2	3.55e-06	2	66	2	28684763
Pubmed	Comparative analyses of disease risk genes belonging to the acyl-CoA synthetase medium-chain (ACSM) family in human liver and cell lines.	ACSM2A ACSM2B	3.55e-06	2	66	2	19634011
Pubmed	The importance of cationic amino acid transporter expression in human skin.	SLC7A1 SLC7A2	3.55e-06	2	66	2	12787129
Pubmed	Dual targeting of phosphoinositide 3-kinase and mammalian target of rapamycin using NVP-BEZ235 as a novel therapeutic approach in human ovarian carcinoma.	PIK3CA MTOR	3.55e-06	2	66	2	21372221
Pubmed	Molecular determinants of renal glucose reabsorption. Focus on "Glucose transport by human renal Na+/D-glucose cotransporters SGLT1 and SGLT2".	SLC5A1 SLC5A2	3.55e-06	2	66	2	21048164
Pubmed	PIK3CA mutations associated with gene signature of low mTORC1 signaling and better outcomes in estrogen receptor-positive breast cancer.	PIK3CA MTOR	3.55e-06	2	66	2	20479250
Pubmed	Retinoic acid receptor-mediated induction of ABCA1 in macrophages.	ABCA1 RARG	3.55e-06	2	66	2	14560020
Pubmed	[PI3K and mTOR pathway and molecular targeted agents].	PIK3CA MTOR	3.55e-06	2	66	2	26281684
Pubmed	Akt2, but not Akt1 or Akt3 mediates pressure-stimulated serum-opsonized latex bead phagocytosis through activating mTOR and p70 S6 kinase.	MTOR AKT2	3.55e-06	2	66	2	17372934
Pubmed	NCAPG2 facilitates glioblastoma cells' malignancy and xenograft tumor growth via HBO1 activation by phosphorylation.	KAT7 NCAPG2	3.55e-06	2	66	2	32897418
Pubmed	Novel targeting of phosphatidylinositol 3-kinase and mammalian target of rapamycin in renal cell carcinoma.	PIK3CA MTOR	3.55e-06	2	66	2	23867512
Pubmed	Human cationic amino acid transporters hCAT-1, hCAT-2A, and hCAT-2B: three related carriers with distinct transport properties.	SLC7A1 SLC7A2	3.55e-06	2	66	2	9174363
Pubmed	Dual inhibition of PI3K and mTOR signaling pathways decreases human pancreatic neuroendocrine tumor metastatic progression.	PIK3CA MTOR	3.55e-06	2	66	2	24263107
Pubmed	GPHR is a novel anion channel critical for acidification and functions of the Golgi apparatus.	GPR89B GPR89A	3.55e-06	2	66	2	18794847
Pubmed	Control of cationic amino acid transport and retroviral receptor functions in a membrane protein family.	SLC7A1 SLC7A2	3.55e-06	2	66	2	8195186
Pubmed	Structural insights of a PI3K/mTOR dual inhibitor with the morpholino-triazine scaffold.	PIK3CA MTOR	3.55e-06	2	66	2	26956874
Pubmed	Increase in SGLT1-mediated transport explains renal glucose reabsorption during genetic and pharmacological SGLT2 inhibition in euglycemia.	SLC5A1 SLC5A2	3.55e-06	2	66	2	24226519
Pubmed	The L513S polymorphism in medium-chain acyl-CoA synthetase 2 (MACS2) is associated with risk factors of the metabolic syndrome in a Caucasian study population.	ACSM2A ACSM2B	3.55e-06	2	66	2	16521160
Pubmed	Ehrlichia Activation of Wnt-PI3K-mTOR Signaling Inhibits Autolysosome Generation and Autophagic Destruction by the Mononuclear Phagocyte.	PIK3CA MTOR	3.55e-06	2	66	2	28993455
Pubmed	Increased Cat3-mediated cationic amino acid transport functionally compensates in Cat1 knockout cell lines.	SLC7A1 SLC7A3	3.55e-06	2	66	2	9614060
Pubmed	Signals mediating skeletal muscle remodeling by resistance exercise: PI3-kinase independent activation of mTORC1.	PIK3CA MTOR	3.55e-06	2	66	2	21071597
Pubmed	Dual phosphoinositide 3-kinase/mammalian target of rapamycin inhibitor is an effective radiosensitizer for colorectal cancer.	PIK3CA MTOR	3.55e-06	2	66	2	25497009
Pubmed	Thioglycosides as inhibitors of hSGLT1 and hSGLT2: potential therapeutic agents for the control of hyperglycemia in diabetes.	SLC5A1 SLC5A2	3.55e-06	2	66	2	17505558
Pubmed	Human cationic amino acid transporters are not affected by direct nitros(yl)ation.	SLC7A1 SLC7A2	3.55e-06	2	66	2	32008093
Pubmed	Superior efficacy of co-treatment with the dual PI3K/mTOR inhibitor BEZ235 and histone deacetylase inhibitor Trichostatin A against NSCLC.	PIK3CA MTOR	3.55e-06	2	66	2	27507059
Pubmed	Crosstalk between the PI3K/mTOR and MEK/ERK pathways involved in the maintenance of self-renewal and tumorigenicity of glioblastoma stem-like cells.	PIK3CA MTOR	3.55e-06	2	66	2	20857497
Pubmed	Identification of a low affinity, high capacity transporter of cationic amino acids in mouse liver.	SLC7A1 SLC7A2	3.55e-06	2	66	2	8385111
Pubmed	In pursuit of synergy: An investigation of the PI3K/mTOR/MEK co-targeted inhibition strategy in NSCLC.	PIK3CA MTOR	3.55e-06	2	66	2	27765909
Pubmed	Renal SGLT mRNA expression in human health and disease: a study in two cohorts.	SLC5A1 SLC5A2	3.55e-06	2	66	2	31545924
Pubmed	Regulation of cationic amino acid transporter (CAT) gene expression.	SLC7A1 SLC7A2	3.55e-06	2	66	2	8878860
Pubmed	The PI3K/mTOR dual inhibitor P7170 demonstrates potent activity against endocrine-sensitive and endocrine-resistant ER+ breast cancer.	PIK3CA MTOR	3.55e-06	2	66	2	25491778
Pubmed	Glucose transport by human renal Na+/D-glucose cotransporters SGLT1 and SGLT2.	SLC5A1 SLC5A2	3.55e-06	2	66	2	20980548
Pubmed	Cell signalling-mediating insulin increase of mRNA expression for cationic amino acid transporters-1 and -2 and membrane hyperpolarization in human umbilical vein endothelial cells.	SLC7A1 SLC7A2	3.55e-06	2	66	2	15064952
Pubmed	Analyses of the genetic diversity and protein expression variation of the acyl: CoA medium-chain ligases, ACSM2A and ACSM2B.	ACSM2A ACSM2B	3.55e-06	2	66	2	29948332
Pubmed	Akt-dependent and isoform-specific regulation of dopamine transporter cell surface expression.	SLC6A3 AKT2	3.55e-06	2	66	2	22778840
Pubmed	Sodium-glucose co-transporter (SGLT)2 and SGLT1 renal expression in patients with type 2 diabetes.	SLC5A1 SLC5A2	3.55e-06	2	66	2	28419670
Pubmed	Human cationic amino acid transporter hCAT-3 is preferentially expressed in peripheral tissues.	SLC7A1 SLC7A3	3.55e-06	2	66	2	11591158
Pubmed	Characterization of cationic amino acid transporters (hCATs) 1 and 2 in human skin.	SLC7A1 SLC7A2	3.55e-06	2	66	2	18172665
Pubmed	Pharmacogenetic analysis of lipid responses to rosuvastatin in Chinese patients.	ABCA1 SLC22A1 ABCC2 ACSM2B	7.80e-06	66	66	4	20679960
Pubmed	Multiple genetic variants along candidate pathways influence plasma high-density lipoprotein cholesterol concentrations.	ABCA1 ADIPOR1 PIK3CA MTOR SCD AKT2	8.23e-06	250	66	6	18660489
Pubmed	[Study of gambogenic acid-induced apoptosis of melanoma B16 cells through PI3K/Akt/mTOR signaling pathways].	PIK3CA MTOR	1.06e-05	3	66	2	25095381
Pubmed	Targeting the PI3K/AKT/mTOR signaling pathway in medulloblastoma.	PIK3CA MTOR	1.06e-05	3	66	2	25601471
Pubmed	Sodium-glucose co-transporter (SGLT) and glucose transporter (GLUT) expression in the kidney of type 2 diabetic subjects.	SLC5A1 SLC5A2	1.06e-05	3	66	2	28477418
Pubmed	Inhibition of the PI3K/Akt/mTOR signaling pathway in diffuse large B-cell lymphoma: current knowledge and clinical significance.	PIK3CA MTOR	1.06e-05	3	66	2	25215588
Pubmed	Association between germline single nucleotide polymorphisms in the PI3K-AKT-mTOR pathway, obesity, and breast cancer disease-free survival.	PIK3CA MTOR	1.06e-05	3	66	2	25108739
Pubmed	Exclusive inhibition of PI3K/Akt/mTOR signaling is not sufficient to prevent PDGF-mediated effects on glycolysis and proliferation in colorectal cancer.	PIK3CA MTOR	1.06e-05	3	66	2	27626684
Pubmed	Improved glycemic control in mice lacking Sglt1 and Sglt2.	SLC5A1 SLC5A2	1.06e-05	3	66	2	23149623
Pubmed	The association of PI3 kinase signaling and chemoresistance in advanced ovarian cancer.	PIK3CA AKT2	1.06e-05	3	66	2	22556379
Pubmed	PI3K/AKT/mTOR pathway is activated after imatinib secondary resistance in gastrointestinal stromal tumors (GISTs).	PIK3CA MTOR	1.06e-05	3	66	2	25757539
Pubmed	Antibodies to a renal Na+/glucose cotransport system localize to the apical plasma membrane domain of polar mouse embryo blastomeres.	SLC5A1 SLC5A2	1.06e-05	3	66	2	1702069
Pubmed	Down-regulation of JAK1 by RNA interference inhibits growth of the lung cancer cell line A549 and interferes with the PI3K/mTOR pathway.	PIK3CA MTOR	1.06e-05	3	66	2	21861134
Pubmed	Nerve growth factor regulates the expression of vascular endothelial growth factor in human HaCaT keratinocytes via PI3K/mTOR pathway.	PIK3CA MTOR	1.06e-05	3	66	2	24615084
Pubmed	The PI3K/AKT/mTOR signaling pathway is overactivated in primary aldosteronism.	PIK3CA MTOR	1.06e-05	3	66	2	23626817
Pubmed	Therapeutic priority of the PI3K/AKT/mTOR pathway in small cell lung cancers as revealed by a comprehensive genomic analysis.	PIK3CA MTOR	1.06e-05	3	66	2	25122428
Pubmed	Palmitate induced insulin resistance by PKCtheta-dependent activation of mTOR/S6K pathway in C2C12 myotubes.	MTOR PRKCQ	1.06e-05	3	66	2	20429048
Pubmed	Akt and mTOR mediate programmed necrosis in neurons.	MTOR AKT2	1.06e-05	3	66	2	24577082
Pubmed	Targeting PI3 kinase/AKT/mTOR signaling in cancer.	PIK3CA MTOR	1.06e-05	3	66	2	22471665
Pubmed	Increased activation of PI3K/AKT signaling pathway is associated with cholangiocarcinoma metastasis and PI3K/mTOR inhibition presents a possible therapeutic strategy.	PIK3CA MTOR	1.06e-05	3	66	2	23832540
Pubmed	Thioridazine inhibits angiogenesis and tumor growth by targeting the VEGFR-2/PI3K/mTOR pathway in ovarian cancer xenografts.	PIK3CA MTOR	1.06e-05	3	66	2	24952635
Pubmed	Correlation between activation of PI3K/AKT/mTOR pathway and prognosis of breast cancer in Chinese women.	PIK3CA MTOR	1.06e-05	3	66	2	25816324
Pubmed	Phosphorylase kinase: the complexity of its regulation is reflected in the complexity of its structure.	PHKA1 PHKG2	1.06e-05	3	66	2	10487978
Pubmed	IL-22 induced cell proliferation is regulated by PI3K/Akt/mTOR signaling cascade.	PIK3CA MTOR	1.06e-05	3	66	2	22840496
Pubmed	Activity of EGFR, mTOR and PI3K inhibitors in an isogenic breast cell line model.	PIK3CA MTOR	1.06e-05	3	66	2	24964744
Pubmed	Post-oral appetite stimulation by sugars and nonmetabolizable sugar analogs.	SLC5A1 SLC5A4	1.06e-05	3	66	2	23926132
Pubmed	Phase I study of neratinib in combination with temsirolimus in patients with human epidermal growth factor receptor 2-dependent and other solid tumors.	PIK3CA MTOR	1.06e-05	3	66	2	24323026
Pubmed	Genomewide analysis of inherited variation associated with phosphorylation of PI3K/AKT/mTOR signaling proteins.	PIK3CA MTOR	1.06e-05	3	66	2	21949775
Pubmed	Reciprocal feedback inhibition of the androgen receptor and PI3K as a novel therapy for castrate-sensitive and -resistant prostate cancer.	PIK3CA MTOR	1.06e-05	3	66	2	26506516
Pubmed	Neuropathological role of PI3K/Akt/mTOR axis in Down syndrome brain.	PIK3CA MTOR	1.06e-05	3	66	2	24735980
Pubmed	Targeting the PI3K pathway in cancer: are we making headway?	PIK3CA MTOR	1.06e-05	3	66	2	29508857
Pubmed	Rate of transport of l-arginine is independent of the expression of inducible nitric oxide synthase in HEK 293 cells.	SLC7A1 SLC7A2	1.06e-05	3	66	2	15631944
Pubmed	Sphingosine kinase 1 expression is regulated by signaling through PI3K, AKT2, and mTOR in human coronary artery smooth muscle cells.	MTOR AKT2	1.06e-05	3	66	2	17482291
Pubmed	Activated mutant forms of PIK3CA cooperate with RasV12 or c-Met to induce liver tumour formation in mice via AKT2/mTORC1 cascade.	PIK3CA AKT2	1.06e-05	3	66	2	26716908
Pubmed	Butein suppresses cervical cancer growth through the PI3K/AKT/mTOR pathway.	PIK3CA MTOR	1.06e-05	3	66	2	25962638
Pubmed	Analysis of the genomic organization of the human cationic amino acid transporters CAT-1, CAT-2 and CAT-4.	SLC7A1 SLC7A2	1.06e-05	3	66	2	11665818
Pubmed	Regulatory effects of mammalian target of rapamycin-mediated signals in the generation of arsenic trioxide responses.	MTOR AKT2	1.06e-05	3	66	2	18048359
Pubmed	Analysis of PI3K/AKT/mTOR signalling pathway in high risk neuroblastic tumours.	PIK3CA MTOR	1.06e-05	3	66	2	21290341
Pubmed	PI3K-PKB-mTOR hyperactivation in relation to nasopharyngeal carcinoma progression and prognosis.	PIK3CA MTOR	1.06e-05	3	66	2	30582216
Pubmed	Puquitinib mesylate (XC-302) induces autophagy via inhibiting the PI3K/AKT/mTOR signaling pathway in nasopharyngeal cancer cells.	PIK3CA MTOR	1.06e-05	3	66	2	26499488
Pubmed	Akt substrate TBC1D1 regulates GLUT1 expression through the mTOR pathway in 3T3-L1 adipocytes.	MTOR TBC1D1	1.06e-05	3	66	2	18215134
Pubmed	Akt and autophagy cooperate to promote survival of drug-resistant glioma.	PIK3CA MTOR	1.06e-05	3	66	2	21062993
Pubmed	Synergistic anti-tumor effect of 17AAG with the PI3K/mTOR inhibitor NVP-BEZ235 on human melanoma.	PIK3CA MTOR	1.06e-05	3	66	2	28774796
Pubmed	Contraction regulates site-specific phosphorylation of TBC1D1 in skeletal muscle.	TBC1D1 AKT2	1.06e-05	3	66	2	20701589
Pubmed	Genetic and structural studies of RABL3 reveal an essential role in lymphoid development and function.	GPR89B GPR89A	1.06e-05	3	66	2	32220963
Interaction	OPALIN interactions	SLC7A2 SLC7A3 MTOR SURF4 GPR89A ABCC2 NCAPG2	2.52e-06	209	59	7	int:OPALIN
Interaction	GPR182 interactions	SLC7A1 SLC7A2 MTOR CCDC47 SCD SURF4 GPR89A NCAPG2 SYMPK	6.50e-06	455	59	9	int:GPR182
Interaction	TSPAN15 interactions	SLC7A1 SLC7A2 ADIPOR1 SURF4 TMEM63B GPR89A SLC5A4	1.55e-05	276	59	7	int:TSPAN15
Interaction	ACSM2A interactions	ACSM2A ACSM2B	5.04e-05	4	59	2	int:ACSM2A
Interaction	ACSM2B interactions	ACSM2A ACSM2B	5.04e-05	4	59	2	int:ACSM2B
Interaction	LAMP3 interactions	SLC7A1 SLC7A2 CCDC47 GPR89A PRKCQ NUBPL SLC1A3 NCAPG2	8.14e-05	486	59	8	int:LAMP3
Cytoband	9q31.1	ABCA1 OR13C9 OR13C5 OR13C2	3.79e-07	41	66	4	9q31.1
Cytoband	Ensembl 112 genes in cytogenetic band chr9q31	ABCA1 OR13C9 OR13C5 OR13C2	4.74e-05	137	66	4	chr9q31
Cytoband	12q21.31	TMTC2 ACSS3	3.07e-04	18	66	2	12q21.31
Cytoband	22q12.3	SLC5A1 SLC5A4	1.04e-03	33	66	2	22q12.3
Cytoband	16p12.3	ACSM2A ACSM2B	1.11e-03	34	66	2	16p12.3
Cytoband	Ensembl 112 genes in cytogenetic band chrXq13	PHKA1 SLC7A3 SLC16A2	1.77e-03	165	66	3	chrXq13
Cytoband	1q21.1	GPR89B GPR89A	3.64e-03	62	66	2	1q21.1
Cytoband	11q24.2	OR8B4 SLC37A2	3.76e-03	63	66	2	11q24.2
GeneFamily	Solute carriers	SLC6A3 SLC7A1 SLC7A2 SLC7A3 SLC16A2 SLC22A1 SLC37A2 SLC1A3 SLC5A1 SLC5A2 SLC5A4	4.05e-09	395	47	11	752
GeneFamily	Olfactory receptors, family 13	OR13C9 OR13C5 OR13C2	2.81e-05	23	47	3	162
GeneFamily	Acyl-CoA synthetase family	ACSM2A ACSS3 ACSM2B	4.10e-05	26	47	3	40
Coexpression	GSE3982_NKCELL_VS_TH1_DN	CCDC47 SCD SLC22A1 ABCC2 SQOR NCAPG2 SYMPK	6.49e-07	200	65	7	M5595
Coexpression	MORI_PLASMA_CELL_UP	GPR89B CCDC47 SURF4 GPR89A	9.92e-06	54	65	4	MM597
Coexpression	GSE7852_LN_VS_THYMUS_TCONV_UP	ADCY10 SLC7A1 SCD MIF4GD SLC37A2 GNS	1.01e-05	199	65	6	M5745
Coexpression	GSE8921_UNSTIM_VS_TLR1_2_STIM_MONOCYTE_12H_DN	SLC7A1 SLC7A2 EML4 NLRC5 AKT2 NCAPG2	1.04e-05	200	65	6	M6419
CoexpressionAtlas	kidney_adult_RenalCortexMixed_Std_top-relative-expression-ranked_500	SCD SLC22A1 ABCC2 ACSM2A SQOR BICC1 SLC5A1 SLC5A2	2.76e-05	424	61	8	gudmap_kidney_adult_RenalCortexMixed_Std_500
CoexpressionAtlas	B cells, B.Fo.MLN, CD19+ CD45R+ CD23+ CD21/35+, Lymph Node, avg-3	PHKA1 ABCA1 EML4 SCD MIF4GD SLC37A2 MAP3K19	5.47e-05	342	61	7	GSM777021_500
CoexpressionAtlas	B cells, B.Fo.Sp, IgD+ IgM+ CD45R+ CD24+ CD19+ AA4.1- CD23+, Spleen, avg-3	PHKA1 ABCA1 EML4 SCD MIF4GD SLC37A2 MAP3K19	5.78e-05	345	61	7	GSM538201_500
CoexpressionAtlas	B cells, B.T3.Sp, IgD+ IgM+ CD45R+ CD24+ CD19+ AA4.1+ CD23+, Spleen, avg-3	PHKA1 ABCA1 EML4 SCD MIF4GD SLC37A2 MAP3K19	7.68e-05	361	61	7	GSM538219_500
ToppCell	COVID-19-kidney-PCT-S2\|COVID-19 / Disease (COVID-19 only), tissue and cell type	ABCC2 ACSM2A BICC1 ACSM2B SLC5A2	7.11e-06	180	66	5	358923e4228035a3e90e2957392089219e90dcd7
ToppCell	droplet-Kidney-nan-18m-Epithelial-Epcam____kidney_proximal_convoluted_tubule_epithelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC16A2 SLC22A1 ABCC2 ACSM2B SLC5A2	7.91e-06	184	66	5	c86ed59fed687cdaaf7e9c4418d2e3e2c4111cca
ToppCell	droplet-Kidney-nan-18m-Epithelial-kidney_proximal_convoluted_tubule_epithelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC16A2 SLC22A1 ABCC2 ACSM2B SLC5A2	7.91e-06	184	66	5	7c256bcfa07c5ff55aad0833e8712b0456b5832b
ToppCell	droplet-Kidney-nan-3m-Epithelial-Epcam____kidney_proximal_convoluted_tubule_epithelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC16A2 SLC22A1 ABCC2 ACSM2B SLC5A2	8.12e-06	185	66	5	3e3217c99719fd1d2fa94e16be7712a7e5077152
ToppCell	droplet-Kidney-nan-3m-Epithelial-kidney_proximal_convoluted_tubule_epithelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC16A2 SLC22A1 ABCC2 ACSM2B SLC5A2	8.12e-06	185	66	5	0ff4148b4701003d9d594e0da8261176fb13aa59
ToppCell	COVID-19-kidney-Mito-rich_PCT\|COVID-19 / Disease (COVID-19 only), tissue and cell type	ABCC2 ACSM2A BICC1 ACSM2B SLC5A2	8.12e-06	185	66	5	1bbc2ba8a20f72f61981b1301cdd6018cdd9150d
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	ABCC2 ACSM2A BICC1 ACSM2B SLC5A2	9.48e-06	191	66	5	3c464645d0e7e423f791bd63bf5bcf11f6b590d3
ToppCell	Fetal_29-31_weeks-Mesenchymal-matrix_fibroblast_1_cell-D088\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	SLC7A2 ABCA1 EML4 SLC1A3 BICC1	9.48e-06	191	66	5	08720998aa55131d7377c4c67c4c935865bd7d79
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	ABCC2 ACSM2A BICC1 ACSM2B SLC5A2	9.48e-06	191	66	5	1c1d13144259b998d4a0e85142f7afef2ef1e63f
ToppCell	facs-Lung-Endomucin-24m-Endothelial-Capillary_Type_1_Cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADCY10 SLC6A3 ABCC2 ACSM2B	6.39e-05	145	66	4	96712c68ab759d7ade0d912581a1a7c25dc6def8
ToppCell	facs-Lung-24m-Endothelial-capillary_endothelial-capillary_endothelial_cell-capillary_type_1_endothelial_cell\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ADCY10 SLC6A3 ABCC2 ACSM2B	9.81e-05	162	66	4	bf886e22ff2a20353499004b53f25fb9e6574896
ToppCell	COVID-mono3\|COVID / Condition, Cell_class and T cell subcluster	ABCA1 SLC22A1 EML1 SLC1A3	1.00e-04	163	66	4	6ab4cbcd411b40920b81162c0f4b03ea67408f52
ToppCell	COVID-mono3-\|COVID / Condition, Cell_class and T cell subcluster	ABCA1 SLC22A1 EML1 SLC1A3	1.00e-04	163	66	4	26661c7a3a0a449ed32d4b3b28fc2fc0b237025d
ToppCell	368C-Myeloid-Dendritic-cDC1\|Dendritic / Donor, Lineage, Cell class and subclass (all cells)	PNMA1 SLC16A2 NLRC5 NUBPL	1.00e-04	163	66	4	299ac2463b7f58eee419d822a2a2d64b973d87e9
ToppCell	PND14-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT2-AT2_prolif\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	SCD LRRTM2 SLC1A3 SLC5A1	1.08e-04	166	66	4	575c325db88d6909cdf0d5e664bd9098b89d4401
ToppCell	frontal_cortex-Non-neuronal-leptomeningeal_cell-VLMC-VLMC_Osr1_Mc5r\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	SLC7A2 SLC1A3 BICC1 ACSS3	1.13e-04	168	66	4	9930bd63b60c03f0152838a79eef77da1c2dd8e5
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_1_/_Segment_2\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ABCC2 ACSM2A ACSM2B SLC5A2	1.13e-04	168	66	4	fa0d251693935116adf633d02b7ec4a295100865
ToppCell	facs-Liver-Hepatocytes-24m-Myeloid-Kupffer_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HCAR2 SLC37A2 SLC1A3 NCAPG2	1.15e-04	169	66	4	454b92b9b67299a64278c010db033ca5b9d217a0
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_1_/_Segment_2\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ABCC2 ACSM2A ACSM2B SLC5A2	1.21e-04	171	66	4	f5014e3c387fe3118944af392abe10d6b9b0abab
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_1_/_Segment_2\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	ABCC2 ACSM2A ACSM2B SLC5A2	1.26e-04	173	66	4	8888434641ea554a9b62c436e87920378eef29cd
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_3\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	ABCC2 ACSM2A ACSM2B SLC5A1	1.35e-04	176	66	4	1595dbeee336a81e581325d63208ec6262664ee9
ToppCell	COVID-19-kidney-Distal_Epi_Doublet_(PCT)\|kidney / Disease (COVID-19 only), tissue and cell type	GPR89B ACSM2A BICC1 ACSM2B	1.35e-04	176	66	4	36f77d878a53b30465b0dea8333a3865dba75613
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_3\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ABCC2 ACSM2A ACSM2B SLC5A1	1.38e-04	177	66	4	2f81b26be89cc2fd8eafadaf7eae3c6ad6521462
ToppCell	COVID-19-kidney-PCT-S1/S2\|COVID-19 / Disease (COVID-19 only), tissue and cell type	ABCC2 ACSM2A ACSM2B SLC5A2	1.41e-04	178	66	4	23a12d3d971b857d5be8e907334d1f6b49eeeb32
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ACSM2A BICC1 ACSM2B SLC5A1	1.44e-04	179	66	4	58ae5a97fe2a14e1c6fdeb886397eb06fdaf0428
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_1_/_Segment_2\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ABCC2 ACSM2A ACSM2B SLC5A2	1.47e-04	180	66	4	f8bdfd7bf7b3d52c659a29d8f5f80858e79da83e
ToppCell	droplet-Kidney-nan-3m-Epithelial-kidney_proximal_straight_tubule_epithelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC16A2 SLC22A1 ACSM2B SLC5A2	1.47e-04	180	66	4	b34d933cdabf692f02eaaf65c2aaca1fb9510627
ToppCell	Control-Stromal_mesenchymal-Matrix_Fibroblast-MatrixFB\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	SLC7A2 SLC1A3 BICC1 ACSS3	1.47e-04	180	66	4	08ae0f5d95c45feba68ad99788f7af7ff4c979af
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_1_/_Segment_2\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	ABCC2 ACSM2A ACSM2B SLC5A2	1.47e-04	180	66	4	1363b3254470f6ff98630d1df83a1bdbacc137e0
ToppCell	COVID-19-kidney-tDL\|COVID-19 / Disease (COVID-19 only), tissue and cell type	ABCC2 ACSM2A ACSM2B SLC5A2	1.47e-04	180	66	4	864c895b5eaedefae86f5829fa344f7b686fb59f
ToppCell	facs-Kidney-nan-18m-Epithelial-kidney_collecting_duct_epithelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC22A1 ABCC2 ACSM2B SLC5A2	1.50e-04	181	66	4	bec7076efe94898213a62db72d171d737949977e
ToppCell	facs-Kidney-nan-18m-Epithelial-kidney_collecting_duct_epithelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC22A1 ABCC2 ACSM2B SLC5A2	1.50e-04	181	66	4	cf149b30b814cf87c9e923ef502cadf7fe4a3597
ToppCell	COVID-19-kidney-Stressed_PCT\|COVID-19 / Disease (COVID-19 only), tissue and cell type	ABCC2 ACSM2A ACSM2B SLC5A2	1.50e-04	181	66	4	6980ea624151da32b7f537f263e40fcb87a02e81
ToppCell	facs-Lung-24m-Hematologic-lymphocytic-Zbtb32+_B_cell-Zbtb32+_B_cell\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	SLC7A1 SCD STK38 GNS	1.54e-04	182	66	4	8737142aa4c8301fb5b0ad5bef596471ac316743
ToppCell	droplet-Kidney-KIDNEY-1m-Epithelial-kidney_proximal_convoluted_tubule_epithelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC16A2 SLC22A1 ACSM2B SLC5A2	1.54e-04	182	66	4	faf0dfa3adc2d2706b6942b5127093ccdc856447
ToppCell	droplet-Kidney-KIDNEY-1m-Epithelial-Epcam____kidney_proximal_convoluted_tubule_epithelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC16A2 SLC22A1 ACSM2B SLC5A2	1.54e-04	182	66	4	be8dd52898525ce6632af0adc2801944f3ac10bd
ToppCell	facs-Lung-24m-Hematologic-lymphocytic-Zbtb32+_B_cell\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	SLC7A1 SCD STK38 GNS	1.54e-04	182	66	4	632014a6e042d09302f4631ca3a1da36af7a7c98
ToppCell	COVID-19-kidney-Distal_Epi_Doublet_(PCT)\|COVID-19 / Disease (COVID-19 only), tissue and cell type	ABCC2 ACSM2A BICC1 ACSM2B	1.54e-04	182	66	4	9d67717a6e13bcb54c1297a3e4e3abf4e51628a3
ToppCell	3'-Parenchyma_lung-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophages-Alveolar_macrophages_L.1.0.5.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ABCA1 SCD SLC1A3 GNS	1.57e-04	183	66	4	103c4c4595d8daa677679fd2fa1e99cd398e56dd
ToppCell	BALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Myeloid-Monocytic-Nonclassical_Monocyte\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	HCAR2 SLC37A2 SLC1A3 GNS	1.57e-04	183	66	4	36b194e366a14ebc4df187bf31c902be3797bfcc
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_1_/_Segment_2\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ABCC2 ACSM2A ACSM2B SLC5A2	1.57e-04	183	66	4	facd6dbe0851b537d70a899ac7485714ab27d071
ToppCell	COVID-19-kidney-PCT-S1\|COVID-19 / Disease (COVID-19 only), tissue and cell type	ABCC2 ACSM2A BICC1 ACSM2B	1.57e-04	183	66	4	6878d14026c3df6aa12e45dfad94b32fa9d9b0b7
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_1_/_Segment_2\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	ABCC2 ACSM2A ACSM2B SLC5A2	1.57e-04	183	66	4	84b64cf728629c3af9a8d2ed15b93adf562c54b8
ToppCell	droplet-Kidney-nan-21m-Epithelial-epithelial_cell_of_proximal_tubule\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC22A1 CDH23 ACSM2B SLC5A2	1.57e-04	183	66	4	01e7256c9e0ce53f8e10f3d3a5be15dedd312426
ToppCell	COVID-19-kidney-PCT-S1\|kidney / Disease (COVID-19 only), tissue and cell type	ACSM2A BICC1 ACSM2B SLC5A1	1.60e-04	184	66	4	51ed1ebfdef45149541917c66cbacad87072e51f
ToppCell	COVID-19-kidney-PCT-S1/S2\|kidney / Disease (COVID-19 only), tissue and cell type	ABCC2 ACSM2A ACSM2B SLC5A2	1.60e-04	184	66	4	dc71f22583fc54b89b242cbb602f4bbe86f576ec
ToppCell	droplet-Kidney-KIDNEY-1m-Epithelial-nan\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC22A1 ACSM2B SLC5A1 SLC5A2	1.67e-04	186	66	4	fa5f602f01de5beec529d9f5208172b2914a952d
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	ABCC2 ACSM2A ACSM2B SLC5A2	1.67e-04	186	66	4	8287146f0ba415ea04475588117d4668ae00f75c
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_3\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ABCC2 ACSM2A ACSM2B SLC5A1	1.67e-04	186	66	4	a417e1e21313a7e05951038cdef5ac672a9f727c
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_1_/_Segment_2\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	ABCC2 ACSM2A ACSM2B SLC5A2	1.67e-04	186	66	4	5784d255e9ca449d375d81938d0fbbd8a7eb44f6
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ABCC2 ACSM2A ACSM2B SLC5A1	1.70e-04	187	66	4	1b82920588f9e26ef1db244d452736d75fcfd342
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	ABCC2 ACSM2A ACSM2B SLC5A2	1.70e-04	187	66	4	71eb26ebf60cb0848e5bf1cd01edccda621aecd8
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ABCC2 ACSM2A ACSM2B SLC5A2	1.70e-04	187	66	4	dcf6475ece5b34d9d58a0d1f51c18acedb19c119
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ABCC2 ACSM2A ACSM2B SLC5A2	1.70e-04	187	66	4	f1356273bd3587b6883295edf15cb9cdb706c057
ToppCell	COVID-19-kidney\|COVID-19 / Disease (COVID-19 only), tissue and cell type	ABCC2 ACSM2A BICC1 ACSM2B	1.70e-04	187	66	4	d23aae9419d460b78b1d4092d7acd9108a47cfbe
ToppCell	COVID-19-kidney-Mito-rich_PCT\|kidney / Disease (COVID-19 only), tissue and cell type	ABCC2 ACSM2A ACSM2B SLC5A2	1.70e-04	187	66	4	738ec2611b4be6a08eedad16b57fba84e1f11fef
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ABCC2 ACSM2A ACSM2B SLC5A1	1.70e-04	187	66	4	c1e4c0345f9bfa0538730bad5ff3fa5240168b25
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ABCC2 ACSM2A ACSM2B SLC5A2	1.74e-04	188	66	4	f3edcefeef2ce19086032d98b243c02a6d542b38
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ABCC2 ACSM2A ACSM2B SLC5A2	1.74e-04	188	66	4	0792432cd4c564dea1102241ea9884f7ced7658c
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	ABCC2 ACSM2A ACSM2B SLC5A2	1.77e-04	189	66	4	204ab61ae606b2d9be0cb6bf6a83a011740693a8
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	ABCC2 ACSM2A ACSM2B SLC5A2	1.77e-04	189	66	4	13fd07cc408a9486f61a7b2c3a132c52d14b438d
ToppCell	COVID-19-kidney-PCT-S2\|kidney / Disease (COVID-19 only), tissue and cell type	ABCC2 ACSM2A BICC1 ACSM2B	1.77e-04	189	66	4	0be5c669b6b308bd98ddb70c84877c62a6244bbd
ToppCell	LPS-IL1RA+antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-Activated_MatrixFB\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	SLC7A2 SLC1A3 BICC1 ACSS3	1.85e-04	191	66	4	b13229bb7f3713a392271aaf5dbae3edd1b9fe5a
ToppCell	droplet-Heart-nan-24m-Mesenchymal\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC16A2 SCD PAM BICC1	1.85e-04	191	66	4	1f660ea2841324d13f63e01f1789e606c2843fc4
ToppCell	LPS-IL1RA-Stromal_mesenchymal-Matrix_Fibroblast\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	SLC7A2 SLC1A3 BICC1 ACSS3	1.88e-04	192	66	4	f4fc2b0121f879bab2bee99dfb5ff2c3ca1c0e1b
ToppCell	Control-Myeloid-TRAM2\|Myeloid / Condition, Lineage and Cell class	ABCA1 NLRC5 SQOR SLC1A3	1.88e-04	192	66	4	571fd71dad361a8b6c1bf9ad7184a89b3fbec667
ToppCell	LPS-IL1RA+antiTNF-Stromal_mesenchymal\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	SLC7A2 SLC1A3 BICC1 ACSS3	1.88e-04	192	66	4	3d0cb19f037f604253d7d728689aeaa94251e92b
ToppCell	LPS-IL1RA-Stromal_mesenchymal-Matrix_Fibroblast-MatrixFB\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	SLC7A2 SLC1A3 BICC1 ACSS3	1.88e-04	192	66	4	deeecd26972241846b4cb998edf0c7a87ff0c4df
ToppCell	LPS-IL1RA+antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-MatrixFB\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	SLC7A2 SLC1A3 BICC1 ACSS3	1.92e-04	193	66	4	fb28717fadd06c3840636d25409ce80c9254bd34
ToppCell	background-Cholangiocytes\|background / Sample and Cell Type and Tumor Cluster (all cells)	RARG BICC1 CALN1 SLC5A1	1.92e-04	193	66	4	9152241073dbe02ac2c11d86bec9b5b529196f6e
ToppCell	LPS-antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-MatrixFB\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	SLC7A2 SLC1A3 BICC1 ACSS3	1.96e-04	194	66	4	60622bd2f75bfe4c37f721cb12f03dab33f2f58d
ToppCell	LPS-antiTNF-Stromal_mesenchymal\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	SLC7A2 SLC1A3 BICC1 ACSS3	1.96e-04	194	66	4	6e13549f697f7478b34fe71f7dd9d63c5d3db22e
ToppCell	facs-Heart-RA-18m-Mesenchymal\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SCD PAM SLC1A3 BICC1	1.96e-04	194	66	4	bc945450b350f597c3ff910d3a14a533d90086a8
ToppCell	TCGA-Thryoid-Primary_Tumor-Thyroid_Papillary_Carcinoma-Classical\|TCGA-Thryoid / Sample_Type by Project: Shred V9	RARG SCD TMEM63B PAM	1.96e-04	194	66	4	b46c54802b8d1e0a0a17f9ed8e82eaf5e7f4849d
ToppCell	facs-Heart-RA-18m-Mesenchymal-fibroblast_of_cardiac_tissue\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SCD PAM SLC1A3 BICC1	2.00e-04	195	66	4	690d6e15d7c863fc8f2d33b1f7bf86f019f415c9
ToppCell	medial-2-Hematologic-IGSF21+_Dendritic\|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	SLC22A1 SLC37A2 PKD1L3 SLC1A3	2.00e-04	195	66	4	bb612979360b2322289545dda3d3c343d005ee6f
ToppCell	Macrophages-Myositis-ILD_01\|World / lung cells shred on cell class, cell subclass, sample id	ABCA1 SLC37A2 SLC1A3 GNS	2.00e-04	195	66	4	eb104f3bb08ab9eca31273c0523a5c90de1f30a9
ToppCell	367C-Myeloid-Macrophage-FABP4+_Macrophage\|Myeloid / Donor, Lineage, Cell class and subclass (all cells)	HCAR2 EML4 SCD SQOR	2.00e-04	195	66	4	f664fe18856065baaa2837fc82ea946e45f6fcc3
ToppCell	medial-Hematologic-IGSF21+_Dendritic-2\|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	SLC22A1 SLC37A2 PKD1L3 SLC1A3	2.00e-04	195	66	4	779130c2cfcbc603955b0c0332b855b22ab6e9e6
ToppCell	3'-Pediatric_IBD-SmallIntestine-Hematopoietic-Myeloid-MMP9+_Inflammatory_macrophage\|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ABCA1 SCD SLC1A3 GNS	2.00e-04	195	66	4	5a7c74f96f213c504abd65e751800da7e03e47d9
ToppCell	medial-Hematologic-IGSF21+_Dendritic\|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	SLC22A1 SLC37A2 PKD1L3 SLC1A3	2.00e-04	195	66	4	330b688d703d53cb7feb29373b5a6e6e529169ec
ToppCell	facs-Heart-RA-18m-Mesenchymal-fibroblast_of_cardiac_tissue\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SCD PAM SLC1A3 BICC1	2.00e-04	195	66	4	5c05e2bcea3d5d7ebe6325f7187ccf83301053d8
ToppCell	367C-Myeloid-Macrophage-FABP4+_Macrophage\|Macrophage / Donor, Lineage, Cell class and subclass (all cells)	HCAR2 EML4 SCD SQOR	2.08e-04	197	66	4	07aee25e17dbb71e49f7da9fd9ed2537f4a72d82
ToppCell	PSB-critical-LOC-Epithelial-Secretory\|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	SCD SURF4 PAM SLC5A1	2.12e-04	198	66	4	e4cbe4032dba0da3fd46817ea9ad86ba9217f747
ToppCell	Bronchial-NucSeq-Immune_Myeloid-Macrophage_other-Macro_CHIT1\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	ABCA1 OR13C5 SLC37A2 SLC1A3	2.12e-04	198	66	4	0b41b3d6c2db795320e8b65d40d85fb8b618cc34
ToppCell	tumor_Lung-Myeloid_cells-mo-Mac\|tumor_Lung / Location, Cell class and cell subclass	ABCA1 SCD SLC1A3 GNS	2.16e-04	199	66	4	77d46acf655029eab23471dc4c4a1b0832b24306
ToppCell	BAL-Control-cDC_0\|Control / Compartment, Disease Groups and Clusters	EML4 SCD SQOR GNS	2.16e-04	199	66	4	4518ffa51ead9da1ddf07bf048b18602e50f0f84
ToppCell	LPS_IL1RA-Mesenchymal_fibroblastic-Fibroblasts-Activated_MatrixFB\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	SLC7A2 ABCA1 SLC1A3 BICC1	2.16e-04	199	66	4	8b86c69aaf60feff53aa782559cfece7342a23de
ToppCell	5'-Parenchyma_lung-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophages-Alveolar_macrophages_L.1.0.3.1\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	HCAR2 EML4 SCD SLC1A3	2.16e-04	199	66	4	8e9862907b15809d083216e7d6a0f435015e5d15
ToppCell	tumor_Lung-Myeloid_cells-mo-Mac\|Myeloid_cells / Location, Cell class and cell subclass	ABCA1 SCD SLC1A3 GNS	2.20e-04	200	66	4	58ff8db0ecf71daa86f9a38208e0d9b712cac0b5
ToppCell	droplet-Trachea-3m-Mesenchymal-fibroblast\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	SLC7A2 SLC16A2 TNN PAM	2.20e-04	200	66	4	be527df943a8cedc6452ecef3cafc282db34ceb8
ToppCell	Mild-Myeloid-Macrophages-FCN1-SPP1+\|Mild / Condition, Lineage, Cell class and cell subclass	ABCA1 SCD SLC37A2 GNS	2.20e-04	200	66	4	e5afd8e2cb2c63899d49fe17011f474d20bb06ea
ToppCell	droplet-Trachea-3m-Mesenchymal-fibroblast-fibroblast_of_trachea\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	SLC7A2 SLC16A2 TNN PAM	2.20e-04	200	66	4	8e41a484038216f0c2ad258fd46c0e702a4bb8bf
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	ACSM2A BICC1 ACSM2B SLC5A2	2.20e-04	200	66	4	105564ee05bd11685b5747ee32d5350cf3c2e2e1
ToppCell	Kidney\|World / Skin and Kidney Cells in Lupus Nephritis Patients.	TBC1D1 ACSM2A BICC1 ACSM2B	2.20e-04	200	66	4	1f99afa1f3c32a2a9cfb4ad33ff4d404e34fac63
ToppCell	droplet-Trachea-nan-3m-Mesenchymal-fibroblast\|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC7A2 SLC16A2 TNN PAM	2.20e-04	200	66	4	c935caef2988f165e96d8f1ef99ae8963ab9377f
ToppCell	Globus_pallidus-Endothelial-MURAL-M1(Rgs5Acta2)-M1_1-MURAL_Mural.Rgs5Acta2.Acta2_(Mural.Rgs5Acta2.Acta2)\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	SLC22A1 ABCC2 SLC5A1	3.13e-04	89	66	3	eeafa9e27d0d22242a2f91774ae78df104337696
ToppCell	Globus_pallidus-Endothelial-MURAL-M1(Rgs5Acta2)-M1_1\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	SLC22A1 ABCC2 SLC5A1	3.13e-04	89	66	3	606fbee8326e55fed7b1fd96d3ae80c0b0cfa3c8
ToppCell	Globus_pallidus-Endothelial-MURAL-M1(Rgs5Acta2)-M1_1-MURAL_Mural.Rgs5Acta2.Acta2_(Mural.Rgs5Acta2.Acta2)-\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	SLC22A1 ABCC2 SLC5A1	3.13e-04	89	66	3	018ea3fd99eca755c1656c08b35d48e5085788d1
Computational	Genes in the cancer module 186.	SLC7A2 SLC16A2 SLC1A3	5.21e-05	20	40	3	MODULE_186
Drug	GF109203X	SLC7A1 SLC7A2 HCAR2 PIK3CA MTOR PRKCQ SLC1A3 SLC5A1 SLC5A2 SLC5A4	3.68e-08	341	64	10	CID000002396
Drug	sodium	SLC6A3 KAT7 GPR89B SLC7A1 SLC7A2 HCAR2 SLC7A3 SLC16A2 MTOR PRKCQ ABCC2 SLC1A3 SLC5A1 SLC5A2 SLC5A4	3.92e-08	944	64	15	CID000000923
Drug	L-Lysine	SLC7A1 SLC7A2 SLC7A3	2.11e-07	5	64	3	DB00123
Drug	3-O-methyl-alpha-D-glucopyranose	PIK3CA GNS SLC5A1 SLC5A2 SLC5A4	5.60e-07	57	64	5	CID000083246
Drug	salicyluric acid	PAM ACSM2A ACSM2B	5.94e-06	13	64	3	CID000010253
Drug	leucine	SLC7A1 SLC7A2 SLC7A3 MTOR AKT2 SLC5A1	7.50e-06	167	64	6	CID000000857
Drug	L-Ornithine	SLC7A1 SLC7A2 SLC7A3	7.54e-06	14	64	3	DB00129
Drug	benzylphenol	SLC5A1 SLC5A2	7.78e-06	2	64	2	CID000024216
Drug	beta-D-glucopyranosylphenyl isothiocyanate	SLC5A1 SLC5A2	7.78e-06	2	64	2	CID004182945
Drug	sergliflozin	SLC5A1 SLC5A2	7.78e-06	2	64	2	CID009824918
Drug	V0509	PIK3CA MTOR AKT2 SLC1A3 NCAPG2 GNS SLC5A1	1.12e-05	272	64	7	CID000102191
Drug	thiazolidinedione	ABCA1 MTOR SCD SLC22A1 AKT2 PRKCQ PKD1L3	1.17e-05	274	64	7	CID000005437
Drug	naBE	SLC7A1 SLC7A2 SLC7A3	1.40e-05	17	64	3	CID000151475
Drug	troglitazone	ABCA1 ADIPOR1 RARG PIK3CA MTOR SCD SLC22A1 AKT2 SLC5A1	1.56e-05	526	64	9	CID000005591
Drug	potassium	GPR89B SLC7A1 SLC7A2 HCAR2 SLC7A3 PNMA1 PIK3CA AKT2 PRKCQ PKD1L3 SLC1A3 SLC5A1	2.08e-05	1008	64	12	CID000000813
Drug	A-443654	PIK3CA MTOR AKT2	2.33e-05	20	64	3	CID010172943
Drug	8-dibenzothiophen-4-yl-2-morpholin-4-yl-chromen-4-one	PIK3CA MTOR	4.65e-05	4	64	2	ctd:C499693
Drug	glutathionyl 4-hydroxy-2-nonenal conjugate	PRKCQ ABCC2	4.65e-05	4	64	2	ctd:C524061
Drug	AC1NUTWC	ACSM2A ACSM2B	4.65e-05	4	64	2	CID005460914
Drug	PD98059	SLC6A3 PIK3CA MTOR SLC5A1 SLC5A2 SLC5A4	4.92e-05	233	64	6	CID000004713
Drug	3-O-methyl-D-glucose	PIK3CA GNS SLC5A1 SLC5A2	5.06e-05	72	64	4	CID000008973
Drug	flavanone	PHKA1 PHKG2 AKT2 SYMPK	6.26e-05	76	64	4	CID000010251
Drug	PI 540	PIK3CA MTOR	7.74e-05	5	64	2	ctd:C544306
Drug	alpha-(methylamino)isobutyric acid	SLC1A3 SLC5A1 SLC5A4	9.00e-05	31	64	3	CID000075725
Drug	sodium ferulate	KAT7 SLC16A2 MTOR GNS	1.11e-04	88	64	4	CID000000709
Drug	AC1L1CV3	PIK3CA MTOR AKT2 SLC5A1 SLC5A2	1.14e-04	169	64	5	CID000002076
Drug	cyclopropen-3-yl	SCD SYMPK	1.16e-04	6	64	2	CID000141453
Drug	sarcolysin	SLC7A1 SLC7A2 SLC7A3 PAM SLC1A3	1.23e-04	172	64	5	CID000004053
Disease	hyperinsulinism (biomarker_via_orthology)	ADIPOR1 SCD PRKCQ	4.56e-06	15	65	3	DOID:2018 (biomarker_via_orthology)
Disease	X-21319 measurement	ACSM2A ACSM2B	4.78e-06	2	65	2	EFO_0800807
Disease	3,4-methyleneheptanoate measurement	SLC22A1 ACSM2A	4.78e-06	2	65	2	EFO_0801011
Disease	X-11478 measurement	ACSM2A ACSM2B	1.43e-05	3	65	2	EFO_0021242
Disease	Glycogen phosphorylase kinase deficiency	PHKA1 PHKG2	2.86e-05	4	65	2	cv:C0268147
Disease	3-hydroxyhexanoate measurement	ACSM2A ACSM2B	4.76e-05	5	65	2	EFO_0800378
Disease	Hemimegalencephaly	PIK3CA MTOR	7.13e-05	6	65	2	C0431391
Disease	indoleacetoylcarnitine measurement	ACSM2A ACSM2B	7.13e-05	6	65	2	EFO_0800106
Disease	glycogen storage disease (is_implicated_in)	PHKA1 PHKG2	1.70e-04	9	65	2	DOID:2747 (is_implicated_in)
Disease	obesity (biomarker_via_orthology)	ABCA1 ADIPOR1 MTOR AKT2	3.16e-04	147	65	4	DOID:9970 (biomarker_via_orthology)
Disease	Non-Small Cell Lung Carcinoma	PIK3CA MTOR EML4 AKT2	3.96e-04	156	65	4	C0007131
Disease	Malformations of Cortical Development	PIK3CA MTOR	4.27e-04	14	65	2	C1955869
Disease	Cortical Dysplasia	PIK3CA MTOR	4.27e-04	14	65	2	C0431380
Disease	autosomal recessive polycystic kidney disease (implicated_via_orthology)	MTOR BICC1	5.62e-04	16	65	2	DOID:0110861 (implicated_via_orthology)
Disease	Glycogen storage disease	PHKA1 PHKG2	6.36e-04	17	65	2	cv:C0017919
Disease	extrahepatic cholestasis (biomarker_via_orthology)	ABCA1 SLC22A1	6.36e-04	17	65	2	DOID:13619 (biomarker_via_orthology)
Disease	end stage renal disease (implicated_via_orthology)	MTOR ABCC2	8.85e-04	20	65	2	DOID:783 (implicated_via_orthology)
Disease	prostate adenocarcinoma (is_implicated_in)	ADIPOR1 AKT2	8.85e-04	20	65	2	DOID:2526 (is_implicated_in)
Disease	Nasopharyngeal carcinoma	PIK3CA AKT2	1.07e-03	22	65	2	C2931822
Disease	Adenocarcinoma of large intestine	PIK3CA AKT2 PRKCQ	1.26e-03	96	65	3	C1319315
Disease	Anhedonia	SLC6A3 SLC1A3	1.28e-03	24	65	2	C0178417
Disease	triglyceride measurement, very low density lipoprotein cholesterol measurement	ABCA1 SLC22A1 SQOR CALN1	1.52e-03	224	65	4	EFO_0004530, EFO_0008317
Disease	triglycerides:total lipids ratio, very low density lipoprotein cholesterol measurement	HCAR2 ABCA1 NLRC5 CALN1	1.55e-03	225	65	4	EFO_0008317, EFO_0020947
Disease	acute kidney failure (implicated_via_orthology)	MTOR SLC22A1	1.62e-03	27	65	2	DOID:3021 (implicated_via_orthology)
Disease	hepatocellular carcinoma (biomarker_via_orthology)	ABCA1 PIK3CA AKT2	1.77e-03	108	65	3	DOID:684 (biomarker_via_orthology)
Disease	Neoplasm of uncertain or unknown behavior of ovary	PIK3CA AKT2	1.87e-03	29	65	2	C0496920
Disease	glutamate measurement	CDH23 SLC1A3	1.87e-03	29	65	2	EFO_0010487
Disease	Ovarian Carcinoma	PIK3CA AKT2	2.00e-03	30	65	2	C0029925
Disease	cholesteryl esters to total lipids in large LDL percentage	ABCA1 NLRC5	2.13e-03	31	65	2	EFO_0022249

Protein segments in the cluster

Peptide	Gene	Start	Entry
LGVVMYEMMCGRLPF	AKT2	336	P31751
KSMMGAPIVYRMLLQ	ACSM2A	306	Q08AH3
IFLRVMSRSMPLFMT	ABCA1	631	O95477
LPQPLIAGMYLMMSV	PAM	191	P19021
VNLAARMMMYYPGIV	ADCY10	411	Q96PN6
MMYIQELRSGLRDMP	DIAPH1	146	O60610
MAYFGVSAALTLMMP	SLC7A2	301	P52569
QYLMGCLPLVLMFDM	BICC1	346	Q9H694
QELGMAMRSLGYMPS	CALN1	101	Q9BXU9
SYRMPVGMPRMDFLI	CDH23	926	Q9H251
QAIGYLLGMMALPMI	SLC16A2	446	P36021
SQPYMFPRMLMKITD	RARG	371	P13631
YMVTMSPRVCFLLMF	OR8B4	131	Q96RC9
LGILTMLRPNMYFMA	ADIPOR1	151	Q96A54
LTMPQYMRQGYGKML	KAT7	476	O95251
PQGRMLMNARYFLEM	PRKCQ	111	Q04759
APMLAAIYAMSMVLK	LRRTM2	11	O43300
AIYAMSMVLKMLPAL	LRRTM2	16	O43300
MGPSRMSLFSLYMVQ	M1AP	56	Q8TC57
GDIPCRLMLFMLAMN	HCAR2	96	Q8TDS4
LAMYMRTQPGLFAEM	PHKA1	901	P46020
MEALLPLMNMVIYSI	CCDC47	376	Q96A33
PMYFLLSQLSLMDVM	OR2T8	56	A6NH00
FNILRFPLSMLPMMI	ABCC2	586	Q92887
VMTPMMNPLIYSLRN	OR13C5	286	Q8NGS8
VMTPMMNPLIYSLRN	OR13C2	286	Q8NGS9
MLRMIMEGQYQFSSP	PHKG2	241	P15735
RMPNLMLMAKESLYS	PIK3CA	281	P42336
LLPNMTQLYMQMVLA	NLRC5	431	Q86WI3
CVMLILAAPMMFLYN	SLC37A2	366	Q8TED4
IMGMYFVSSVLLIRM	GPR89A	386	B7ZAQ6
IMGMYFVSSVLLIRM	GPR89B	386	P0CG08
FSFPGELLMRMLQML	SLC1A3	81	P43003
NAMDLLRIPGLLMYM	TMEM63B	581	Q5T3F8
DPELLGKMNYRLMML	GNS	496	P15586
YVKMFLRGRPVTMYM	EML1	186	O00423
YIKMFMRGRPITMFI	EML4	226	Q9HC35
PLKQIPMNLFIMYMA	EMC4	76	Q5J8M3
AAMPQVSYRMLGRMF	PNMA1	41	Q8ND90
VLMAFSPNYMSMLLF	SLC22A1	191	O15245
LLPLMSIFVNIYLMM	SLC7A3	546	Q8WY07
PLASMDRMAAMFYIG	MAP3K19	1266	Q56UN5
MRPLLNYGIACMSMG	NUBPL	131	Q8TB37
IFDYLRVNNMPMMAL	MIF4GD	111	A9UHW6
VMTPMMNPLIYSLRN	OR13C9	286	Q8NGT0
YKRILTPQVMLGMSM	OR52I1	136	Q8NGK6
MNPAFVMPFLRKMLI	MTOR	721	P42345
MPLIYMNIMLAFTIS	MT-ND4L	1	P03901
RLSMYLMKADLMPFL	SQOR	411	Q9Y6N5
NLYLIMEFLPGGDMM	STK38	161	Q15208
TFLYSLMMSRMPRLN	PKD1L3	1211	Q7Z443
FLMVMPGMISRILYT	SLC5A4	326	Q9NY91
YMQLGGRVLLVLMFM	SURF4	156	O15260
YMLQGASSMLPVMAL	NOP2	366	P46087
KSMMGAPIVYRMLLQ	ACSM2B	306	Q68CK6
PMIPQAMYTMLACAR	ACSS3	176	Q9H6R3
RCKIPLFMLMSFMPA	NCAPG2	666	Q86XI2
PMMVRGLCTALGIYM	CLEC20A	241	Q6ZU45
LCGYLKLTPMFLMVM	SLC5A2	316	P31639
FLMVMPGMISRILYP	SLC5A2	326	P31639
MSLQEMFRFPMGLLL	TNN	1	Q9UQP3
LLGSMFPMPRVIYAM	SLC7A1	351	P30825
YNMMGEAYMRLSKLP	TMTC2	646	Q8N394
MVIAGMPLFYMELAL	SLC6A3	106	Q01959
LMFDMGLRKQYRPDM	TBC1D1	916	Q86TI0
VMFQRRYYKPGLLMM	SCD	211	O00767
MLLMRTVIQSLTMYP	SYMPK	996	Q92797
FIMVMPGMISRILYT	SLC5A1	326	P13866
PILSSGMFIMVVRMF	TRIP12	661	Q14669