Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	transmembrane-ephrin receptor activity	EPHB2 EPHA6 EPHA3	8.31e-06	15	54	3	GO:0005005
GeneOntologyMolecularFunction	ephrin receptor activity	EPHB2 EPHA6 EPHA3	1.76e-05	19	54	3	GO:0005003
GeneOntologyMolecularFunction	histone H3K27 methyltransferase activity	JARID2 EHMT1	1.07e-04	6	54	2	GO:0046976
GeneOntologyMolecularFunction	metallopeptidase activity	EEF1AKMT4-ECE2 LTA4H MME ECE1 ECE2	2.04e-04	200	54	5	GO:0008237
GeneOntologyMolecularFunction	metalloendopeptidase activity	EEF1AKMT4-ECE2 MME ECE1 ECE2	3.11e-04	120	54	4	GO:0004222
GeneOntologyMolecularFunction	transmembrane receptor protein tyrosine kinase activity	EPHB2 EPHA6 EPHA3	7.25e-04	65	54	3	GO:0004714
GeneOntologyBiologicalProcess	import into cell	LRRC8C MRC1 FCHSD2 PTPRJ PACSIN1 ABCA13 SYNE1 UNC13D SPG11 SLC9C2 PACSIN2 PRNP EPHA3	2.90e-06	1074	54	13	GO:0098657
GeneOntologyBiologicalProcess	substance P catabolic process	MME ECE1	2.01e-05	3	54	2	GO:0010814
GeneOntologyBiologicalProcess	peptide catabolic process	LTA4H MME ECE1	2.89e-05	23	54	3	GO:0043171
GeneOntologyBiologicalProcess	synaptic signaling	EPHB2 GAD2 FCHSD2 AKAP9 NETO1 SYNE1 SPG11 MME PACSIN2 PRNP KPNA1	3.71e-05	976	54	11	GO:0099536
GeneOntologyBiologicalProcess	endocytosis	MRC1 FCHSD2 PTPRJ PACSIN1 ABCA13 SYNE1 UNC13D SPG11 PACSIN2 EPHA3	4.90e-05	827	54	10	GO:0006897
GeneOntologyBiologicalProcess	neuropeptide catabolic process	MME ECE1	6.69e-05	5	54	2	GO:0010813
GeneOntologyBiologicalProcess	anterograde trans-synaptic signaling	EPHB2 GAD2 FCHSD2 AKAP9 NETO1 SYNE1 SPG11 MME PACSIN2 PRNP	1.31e-04	931	54	10	GO:0098916
GeneOntologyBiologicalProcess	chemical synaptic transmission	EPHB2 GAD2 FCHSD2 AKAP9 NETO1 SYNE1 SPG11 MME PACSIN2 PRNP	1.31e-04	931	54	10	GO:0007268
GeneOntologyBiologicalProcess	bradykinin catabolic process	MME ECE1	1.40e-04	7	54	2	GO:0010815
GeneOntologyBiologicalProcess	trans-synaptic signaling	EPHB2 GAD2 FCHSD2 AKAP9 NETO1 SYNE1 SPG11 MME PACSIN2 PRNP	1.41e-04	939	54	10	GO:0099537
GeneOntologyBiologicalProcess	cell morphogenesis	EPHB2 EPHA6 PTPRJ PACSIN1 SYNE1 SPG11 TECTA ECE1 PACSIN2 EPB42 EPHA3	2.24e-04	1194	54	11	GO:0000902
GeneOntologyBiologicalProcess	signaling receptor ligand precursor processing	MME ECE1 ECE2	2.38e-04	46	54	3	GO:0140448
GeneOntologyBiologicalProcess	ephrin receptor signaling pathway	EPHB2 EPHA6 EPHA3	3.83e-04	54	54	3	GO:0048013
GeneOntologyBiologicalProcess	regulation of signaling receptor activity	EPHB2 PTPRJ NETO1 DAPK1	3.84e-04	131	54	4	GO:0010469
GeneOntologyCellularComponent	neuron to neuron synapse	EPHB2 AKAP9 PACSIN1 NETO1 DAPK1 CSMD2 PRNP KPNA1	5.50e-05	523	54	8	GO:0098984
GeneOntologyCellularComponent	Weibel-Palade body	UNC13D ECE1	9.76e-05	6	54	2	GO:0033093
GeneOntologyCellularComponent	postsynaptic density	AKAP9 PACSIN1 NETO1 DAPK1 CSMD2 PRNP KPNA1	1.53e-04	451	54	7	GO:0014069
GeneOntologyCellularComponent	asymmetric synapse	AKAP9 PACSIN1 NETO1 DAPK1 CSMD2 PRNP KPNA1	2.16e-04	477	54	7	GO:0032279
GeneOntologyCellularComponent	postsynaptic specialization	AKAP9 PACSIN1 NETO1 DAPK1 CSMD2 PRNP KPNA1	2.98e-04	503	54	7	GO:0099572
GeneOntologyCellularComponent	dendrite	EPHB2 AKAP9 EPHA6 SYNE1 SPG11 MME PRNP EPHA3 KPNA1	3.20e-04	858	54	9	GO:0030425
GeneOntologyCellularComponent	dendritic tree	EPHB2 AKAP9 EPHA6 SYNE1 SPG11 MME PRNP EPHA3 KPNA1	3.26e-04	860	54	9	GO:0097447
GeneOntologyCellularComponent	axon	EPHB2 GAD2 PACSIN1 NETO1 POLG PYGB SPG11 MME PRNP	4.22e-04	891	54	9	GO:0030424
GeneOntologyCellularComponent	postsynaptic membrane	EPHB2 AKAP9 PACSIN1 NETO1 SYNE1 CSMD2	6.00e-04	405	54	6	GO:0045211
GeneOntologyCellularComponent	synaptic membrane	EPHB2 GAD2 AKAP9 PACSIN1 NETO1 SYNE1 CSMD2	7.20e-04	583	54	7	GO:0097060
GeneOntologyCellularComponent	postsynaptic density membrane	AKAP9 PACSIN1 NETO1 CSMD2	7.23e-04	157	54	4	GO:0098839
GeneOntologyCellularComponent	azurophil granule	RNASE2 ABCA13 PYGB UNC13D	7.76e-04	160	54	4	GO:0042582
GeneOntologyCellularComponent	primary lysosome	RNASE2 ABCA13 PYGB UNC13D	7.76e-04	160	54	4	GO:0005766
GeneOntologyCellularComponent	somatodendritic compartment	EPHB2 GAD2 AKAP9 EPHA6 SYNE1 SPG11 MME PRNP EPHA3 KPNA1	1.06e-03	1228	54	10	GO:0036477
GeneOntologyCellularComponent	postsynapse	EPHB2 AKAP9 PACSIN1 NETO1 SYNE1 DAPK1 CSMD2 PRNP KPNA1	1.10e-03	1018	54	9	GO:0098794
GeneOntologyCellularComponent	glutamatergic synapse	EPHB2 AKAP9 PACSIN1 NETO1 DAPK1 CSMD2 PACSIN2 KPNA1	1.11e-03	817	54	8	GO:0098978
GeneOntologyCellularComponent	azurophil granule lumen	RNASE2 PYGB UNC13D	1.69e-03	91	54	3	GO:0035578
GeneOntologyCellularComponent	cytoplasmic vesicle membrane	EEF1AKMT4-ECE2 MRC1 GAD2 PTPRJ PACSIN1 ABCA13 MME ECE1 PACSIN2 ECE2	1.69e-03	1307	54	10	GO:0030659
GeneOntologyCellularComponent	postsynaptic specialization membrane	AKAP9 PACSIN1 NETO1 CSMD2	1.80e-03	201	54	4	GO:0099634
GeneOntologyCellularComponent	vesicle membrane	EEF1AKMT4-ECE2 MRC1 GAD2 PTPRJ PACSIN1 ABCA13 MME ECE1 PACSIN2 ECE2	1.87e-03	1325	54	10	GO:0012506
GeneOntologyCellularComponent	ruffle membrane	PTPRJ PACSIN1 PACSIN2	2.75e-03	108	54	3	GO:0032587
GeneOntologyCellularComponent	neuron projection terminus	PACSIN1 POLG MME PRNP	3.08e-03	233	54	4	GO:0044306
GeneOntologyCellularComponent	secretory granule	RNASE2 PTPRJ ABCA13 PYGB UNC13D LTA4H MME ECE1	4.27e-03	1014	54	8	GO:0030141
GeneOntologyCellularComponent	secretory vesicle	GAD2 RNASE2 PTPRJ ABCA13 PYGB UNC13D LTA4H MME ECE1	4.33e-03	1246	54	9	GO:0099503
GeneOntologyCellularComponent	lysosome	FUT10 RNASE2 ABCA13 PYGB UNC13D SPG11 ECE1	4.67e-03	811	54	7	GO:0005764
GeneOntologyCellularComponent	lytic vacuole	FUT10 RNASE2 ABCA13 PYGB UNC13D SPG11 ECE1	4.67e-03	811	54	7	GO:0000323
GeneOntologyCellularComponent	Golgi apparatus subcompartment	AKAP9 PACSIN1 MME PACSIN2 ECE2	5.63e-03	443	54	5	GO:0098791
Domain	Peptidase_M13	MME ECE1 ECE2	6.66e-07	7	51	3	PF01431
Domain	Peptidase_M13_C	MME ECE1 ECE2	6.66e-07	7	51	3	IPR018497
Domain	Peptidase_M13	MME ECE1 ECE2	6.66e-07	7	51	3	IPR000718
Domain	Peptidase_M13_N	MME ECE1 ECE2	6.66e-07	7	51	3	PF05649
Domain	Peptidase_M13_N	MME ECE1 ECE2	6.66e-07	7	51	3	IPR008753
Domain	RECEPTOR_TYR_KIN_V_2	EPHB2 EPHA6 EPHA3	6.84e-06	14	51	3	PS00791
Domain	RECEPTOR_TYR_KIN_V_1	EPHB2 EPHA6 EPHA3	6.84e-06	14	51	3	PS00790
Domain	Eph_TM	EPHB2 EPHA6 EPHA3	6.84e-06	14	51	3	IPR027936
Domain	Tyr_kinase_rcpt_V_CS	EPHB2 EPHA6 EPHA3	6.84e-06	14	51	3	IPR001426
Domain	EPH_lbd	EPHB2 EPHA6 EPHA3	6.84e-06	14	51	3	SM00615
Domain	Ephrin_lbd	EPHB2 EPHA6 EPHA3	6.84e-06	14	51	3	PF01404
Domain	EphA2_TM	EPHB2 EPHA6 EPHA3	6.84e-06	14	51	3	PF14575
Domain	Tyr_kinase_ephrin_rcpt	EPHB2 EPHA6 EPHA3	6.84e-06	14	51	3	IPR016257
Domain	Ephrin_rcpt_lig-bd_dom	EPHB2 EPHA6 EPHA3	6.84e-06	14	51	3	IPR001090
Domain	EPH_LBD	EPHB2 EPHA6 EPHA3	6.84e-06	14	51	3	PS51550
Domain	FCH	FCHSD2 PACSIN1 PACSIN2	2.85e-05	22	51	3	PF00611
Domain	FCH	FCHSD2 PACSIN1 PACSIN2	2.85e-05	22	51	3	SM00055
Domain	FCH_dom	FCHSD2 PACSIN1 PACSIN2	3.27e-05	23	51	3	IPR001060
Domain	Ephrin_rec_like	EPHB2 EPHA6 EPHA3	4.23e-05	25	51	3	SM01411
Domain	F_BAR	FCHSD2 PACSIN1 PACSIN2	4.23e-05	25	51	3	IPR031160
Domain	Tyr-kin_ephrin_A/B_rcpt-like	EPHB2 EPHA6 EPHA3	4.23e-05	25	51	3	IPR011641
Domain	F_BAR	FCHSD2 PACSIN1 PACSIN2	4.23e-05	25	51	3	PS51741
Domain	ZINC_PROTEASE	LTA4H MME ECE1 ECE2	1.47e-04	98	51	4	PS00142
Domain	Ephrin_rec_like	EPHB2 EPHA3	3.96e-04	11	51	2	PF07699
Domain	fn3	EPHB2 EPHA6 PTPRJ EPHA3	9.92e-04	162	51	4	PF00041
Domain	-	EPHB2 EPHA6 EPHA3	1.04e-03	73	51	3	2.60.120.260
Domain	MetalloPept_cat_dom	MME ECE1 ECE2	1.41e-03	81	51	3	IPR024079
Domain	-	MME ECE1 ECE2	1.41e-03	81	51	3	3.40.390.10
Domain	FN3	EPHB2 EPHA6 PTPRJ EPHA3	1.62e-03	185	51	4	SM00060
Domain	TyrKc	EPHB2 EPHA6 EPHA3	1.79e-03	88	51	3	SM00219
Domain	SAM	EPHB2 EPHA6 EPHA3	1.79e-03	88	51	3	SM00454
Domain	Tyr_kinase_cat_dom	EPHB2 EPHA6 EPHA3	1.79e-03	88	51	3	IPR020635
Domain	FN3	EPHB2 EPHA6 PTPRJ EPHA3	2.11e-03	199	51	4	PS50853
Domain	Galactose-bd-like	EPHB2 EPHA6 EPHA3	2.16e-03	94	51	3	IPR008979
Domain	SAM_DOMAIN	EPHB2 EPHA6 EPHA3	2.22e-03	95	51	3	PS50105
Domain	PROTEIN_KINASE_TYR	EPHB2 EPHA6 EPHA3	2.36e-03	97	51	3	PS00109
Domain	SAM	EPHB2 EPHA6 EPHA3	2.36e-03	97	51	3	IPR001660
Domain	Tyr_kinase_AS	EPHB2 EPHA6 EPHA3	2.36e-03	97	51	3	IPR008266
Domain	FN3_dom	EPHB2 EPHA6 PTPRJ EPHA3	2.52e-03	209	51	4	IPR003961
Domain	-	EPHB2 EPHA6 EPHA3	3.04e-03	106	51	3	1.10.150.50
Domain	SAM/pointed	EPHB2 EPHA6 EPHA3	4.01e-03	117	51	3	IPR013761
Domain	Pkinase_Tyr	EPHB2 EPHA6 EPHA3	5.26e-03	129	51	3	PF07714
Domain	Ser-Thr/Tyr_kinase_cat_dom	EPHB2 EPHA6 EPHA3	6.34e-03	138	51	3	IPR001245
Domain	CUB	NETO1 CSMD2	7.92e-03	49	51	2	PF00431
Pubmed	Regulation of steady-state beta-amyloid levels in the brain by neprilysin and endothelin-converting enzyme but not angiotensin-converting enzyme.	MME ECE1 ECE2	3.53e-08	5	54	3	16912050
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	USP53 FUT10 EPHA6 PTPRJ NETO1 POLG EHMT1 MME PPM1K TECTA CFAP69 TASOR2 KPNA1	3.31e-07	1489	54	13	28611215
Pubmed	HENA, heterogeneous network-based data set for Alzheimer's disease.	AKAP9 PACSIN1 SYNE1 DNAJC7 PACSIN2	1.24e-06	120	54	5	31413325
Pubmed	Molecular mechanism of membrane constriction and tubulation mediated by the F-BAR protein Pacsin/Syndapin.	PACSIN1 PACSIN2	2.37e-06	2	54	2	19549836
Pubmed	PACSIN 2, a novel member of the PACSIN family of cytoplasmic adapter proteins.	PACSIN1 PACSIN2	2.37e-06	2	54	2	10431838
Pubmed	Human endothelin converting enzyme-2 (ECE2): characterization of mRNA species and chromosomal localization.	EEF1AKMT4-ECE2 ECE2	2.37e-06	2	54	2	11718899
Pubmed	Endothelin-converting enzymes degrade α-synuclein and are reduced in dementia with Lewy bodies.	ECE1 ECE2	2.37e-06	2	54	2	28171705
Pubmed	Distribution of endothelin-converting enzyme-1 and neutral endopeptidase in human endometrium.	MME ECE1	2.37e-06	2	54	2	17712175
Pubmed	The role of ECE1 variants in cognitive ability in old age and Alzheimer's disease risk.	ECE1 ECE2	2.37e-06	2	54	2	22693153
Pubmed	The tyrosine phosphatase CD148 interacts with the p85 regulatory subunit of phosphoinositide 3-kinase.	PTPRJ PIK3CD	2.37e-06	2	54	2	18348712
Pubmed	Disruption of ECE-1 and ECE-2 reveals a role for endothelin-converting enzyme-2 in murine cardiac development.	ECE1 ECE2	2.37e-06	2	54	2	10811845
Pubmed	Molecular and functional evidence for early divergence of an endothelin-like system during metazoan evolution: analysis of the Cnidarian, hydra.	ECE1 ECE2	2.37e-06	2	54	2	11290299
Pubmed	Major amyloid-β-degrading enzymes, endothelin-converting enzyme-2 and neprilysin, are expressed by distinct populations of GABAergic interneurons in hippocampus and neocortex.	ECE1 ECE2	2.37e-06	2	54	2	27644077
Pubmed	Disruption of segmental neural crest migration and ephrin expression in delta-1 null mice.	EPHB2 EPHA6 EPHA3	2.37e-06	17	54	3	12217323
Pubmed	Expression of Ephs and ephrins in developing mouse inner ear.	EPHB2 EPHA6 EPHA3	3.37e-06	19	54	3	12684176
Pubmed	Unified nomenclature for Eph family receptors and their ligands, the ephrins. Eph Nomenclature Committee.	EPHB2 EPHA6 EPHA3	4.61e-06	21	54	3	9267020
Pubmed	Eph receptors and ephrins demarcate cerebellar lobules before and during their formation.	EPHB2 EPHA6 EPHA3	4.61e-06	21	54	3	10495276
Pubmed	Developmental expression of Eph and ephrin family genes in mammalian small intestine.	EPHB2 EPHA6 EPHA3	4.61e-06	21	54	3	20112066
Pubmed	Roles of Eph receptors and ephrins in segmental patterning.	EPHB2 EPHA6 EPHA3	4.61e-06	21	54	3	11128993
Pubmed	Eph receptors and ephrins: regulators of guidance and assembly.	EPHB2 EPHA6 EPHA3	4.61e-06	21	54	3	10730216
Pubmed	Promotion of proliferation in the developing cerebral cortex by EphA4 forward signaling.	EPHB2 EPHA6 EPHA3	6.13e-06	23	54	3	19542359
Pubmed	Thalamic afferents influence cortical progenitors via ephrin A5-EphA4 interactions.	EPHB2 EPHA6 EPHA3	6.13e-06	23	54	3	25480914
Pubmed	Eph receptors and their ephrin ligands are expressed in developing mouse pancreas.	EPHB2 EPHA6 EPHA3	7.00e-06	24	54	3	16446123
Pubmed	Periodontal disease and gene-expression levels of metalloendopeptidases in human buccal mucosal epithelium.	MME ECE1	7.09e-06	3	54	2	23360525
Pubmed	Identification of ocular regulatory functions of core histone variant H3.2.	EPHB2 EPHA3	7.09e-06	3	54	2	36529279
Pubmed	Expression and functional profiling of neprilysin, insulin-degrading enzyme, and endothelin-converting enzyme in prospectively studied elderly and Alzheimer's brain.	MME ECE1	7.09e-06	3	54	2	20663017
Pubmed	Eph receptor function is modulated by heterooligomerization of A and B type Eph receptors.	EPHB2 EPHA3	7.09e-06	3	54	2	22144690
Pubmed	Toward an optimal joint recognition of the S1' subsites of endothelin converting enzyme-1 (ECE-1), angiotensin converting enzyme (ACE), and neutral endopeptidase (NEP).	MME ECE1	7.09e-06	3	54	2	11906289
Pubmed	Alzheimer's disease beta-amyloid peptide is increased in mice deficient in endothelin-converting enzyme.	ECE1 ECE2	7.09e-06	3	54	2	12464614
Pubmed	[Association of CD133 and endothelin-converting enzyme expressions with prognosis of non-small cell lung carcinoma].	ECE1 ECE2	7.09e-06	3	54	2	17545092
Pubmed	Altered expression of enzymes regulating the activity of endothelin-1 in the lower segment of the human amnion during labor.	MME ECE1	7.09e-06	3	54	2	23863409
Pubmed	Physiological relevance of hydrolysis of atrial natriuretic peptide by endothelin-converting enzyme-1.	MME ECE1	7.09e-06	3	54	2	22972025
Pubmed	A dual-strategy expression screen for candidate connectivity labels in the developing thalamus.	EPHB2 EPHA6 NETO1 EPHA3	1.25e-05	91	54	4	28558017
Pubmed	EHD proteins associate with syndapin I and II and such interactions play a crucial role in endosomal recycling.	PACSIN1 PACSIN2	1.42e-05	4	54	2	15930129
Pubmed	PACSIN 3 is a novel SH3 domain cytoplasmic adapter protein of the pacsin-syndapin-FAP52 gene family.	PACSIN1 PACSIN2	1.42e-05	4	54	2	11179684
Pubmed	Nesprin-1α-Dependent Microtubule Nucleation from the Nuclear Envelope via Akap450 Is Necessary for Nuclear Positioning in Muscle Cells.	AKAP9 SYNE1	1.42e-05	4	54	2	28966089
Pubmed	PACSINs bind to the TRPV4 cation channel. PACSIN 3 modulates the subcellular localization of TRPV4.	PACSIN1 PACSIN2	1.42e-05	4	54	2	16627472
Pubmed	Polymorphism in endothelin-related genes limits exercise-induced decreases in arterial stiffness in older subjects.	ECE1 ECE2	1.42e-05	4	54	2	16567585
Pubmed	Essential role of PACSIN2/syndapin-II in caveolae membrane sculpting.	PACSIN1 PACSIN2	1.42e-05	4	54	2	21610094
Pubmed	Compensatory Actions of Ldb Adaptor Proteins During Corticospinal Motor Neuron Differentiation.	EPHB2 EPHA6 EPHA3	1.87e-05	33	54	3	26830346
Pubmed	Na, K-ATPase α3 is a death target of Alzheimer patient amyloid-β assembly.	EPHB2 PRNP	2.36e-05	5	54	2	26224839
Pubmed	Increasing the Receptor Tyrosine Kinase EphB2 Prevents Amyloid-β-induced Depletion of Cell Surface Glutamate Receptors by a Mechanism That Requires the PDZ-binding Motif of EphB2 and Neuronal Activity.	EPHB2 PRNP	2.36e-05	5	54	2	26589795
Pubmed	SPOP mutation induces DNA methylation via stabilizing GLP/G9a.	BRD4 EHMT1	2.36e-05	5	54	2	34588438
Pubmed	A jumonji (Jarid2) protein complex represses cyclin D1 expression by methylation of histone H3-K9.	JARID2 EHMT1	2.36e-05	5	54	2	19010785
Pubmed	Embryonic stem cells express multiple Eph-subfamily receptor tyrosine kinases.	EPHB2 EPHA3	2.36e-05	5	54	2	8552593
Pubmed	Multiple signaling interactions of Abl and Arg kinases with the EphB2 receptor.	EPHB2 EPHA3	2.36e-05	5	54	2	11494128
Pubmed	Large-scale proteomics and phosphoproteomics of urinary exosomes.	PTPRJ SLC6A19 LTA4H MME TECTA ECE1 DNAJC7 PACSIN2 PRNP	2.44e-05	1016	54	9	19056867
Pubmed	Characterization of the zinc-induced Shank3 interactome of mouse synaptosome.	PACSIN1 DNAJC7 PRNP TASOR2	2.56e-05	109	54	4	29111324
Pubmed	PlexinA1 signaling directs the segregation of proprioceptive sensory axons in the developing spinal cord.	EPHB2 EPHA6 NETO1 EPHA3	3.38e-05	117	54	4	17145500
Pubmed	PACSIN proteins bind tubulin and promote microtubule assembly.	PACSIN1 PACSIN2	3.54e-05	6	54	2	18456257
Pubmed	All three PACSIN isoforms bind to endocytic proteins and inhibit endocytosis.	PACSIN1 PACSIN2	3.54e-05	6	54	2	11082044
Pubmed	PICK1 interacts with PACSIN to regulate AMPA receptor internalization and cerebellar long-term depression.	PACSIN1 PACSIN2	3.54e-05	6	54	2	23918399
Pubmed	Quantitative genetic analysis of brain copper and zinc in BXD recombinant inbred mice.	EPHA6 EPHA3	3.54e-05	6	54	2	16910173
Pubmed	Opposing gradients of ephrin-As and EphA7 in the superior colliculus are essential for topographic mapping in the mammalian visual system.	EPHA6 EPHA3	3.54e-05	6	54	2	15996548
Pubmed	Signals transduced by Ca(2+)/calcineurin and NFATc3/c4 pattern the developing vasculature.	EPHB2 EPHA6 EPHA3	3.89e-05	42	54	3	11439183
Pubmed	Complex formation between EphB2 and Src requires phosphorylation of tyrosine 611 in the EphB2 juxtamembrane region.	EPHB2 EPHA3	4.94e-05	7	54	2	9632142
Pubmed	Mistargeting hippocampal axons by expression of a truncated Eph receptor.	EPHA6 EPHA3	6.59e-05	8	54	2	12124402
Pubmed	Regulation of FasL expression: a SH3 domain containing protein family involved in the lysosomal association of FasL.	PACSIN1 PACSIN2	6.59e-05	8	54	2	16318909
Pubmed	Mis-expression of L1 on pre-crossing spinal commissural axons disrupts pathfinding at the ventral midline.	EPHB2 GAD2	6.59e-05	8	54	2	17884558
Pubmed	Expression and requirement of T-box transcription factors Tbx2 and Tbx3 during secondary palate development in the mouse.	EPHB2 EPHA6 EPHA3	6.99e-05	51	54	3	19769959
Pubmed	Mutational profiling of kinases in human tumours of pancreatic origin identifies candidate cancer genes in ductal and ampulla of vater carcinomas.	EPHB2 EPHA3	8.46e-05	9	54	2	20838624
Pubmed	Degenerate PCR-based cloning method for Eph receptors and analysis of their expression in the developing murine central nervous system and vasculature.	EPHB2 EPHA3	8.46e-05	9	54	2	11403717
Pubmed	The Cellular Phase of Alzheimer's Disease.	EPHB2 PRNP	8.46e-05	9	54	2	26871627
Pubmed	Harnessing host enhancers of SARS-CoV-2 entry as novel targets for antiviral therapy.	EPHB2 PTPRJ ECE1	8.77e-05	55	54	3	38945485
Pubmed	Embryonic expression of EphA receptor genes in mice supports their candidacy for involvement in cleft lip and palate.	EPHA6 EPHA3	1.06e-04	10	54	2	25073978
Pubmed	Quantitative assessment of computational models for retinotopic map formation.	EPHA6 EPHA3	1.06e-04	10	54	2	25367067
Pubmed	EphrinA5 Signaling Is Required for the Distinctive Targeting of Raphe Serotonin Neurons in the Forebrain.	EPHA6 EPHA3	1.06e-04	10	54	2	28197551
Pubmed	HOXA13 directly regulates EphA6 and EphA7 expression in the genital tubercle vascular endothelia.	EPHB2 EPHA6	1.06e-04	10	54	2	17304517
Pubmed	EphA receptors inhibit anti-CD3-induced apoptosis in thymocytes.	EPHA6 EPHA3	1.06e-04	10	54	2	16547242
Pubmed	Bidirectional ephrinB3/EphA4 signaling mediates the segregation of medial ganglionic eminence- and preoptic area-derived interneurons in the deep and superficial migratory stream.	EPHB2 EPHA3	1.29e-04	11	54	2	22171039
Pubmed	Competition is a driving force in topographic mapping.	EPHB2 EPHA6	1.29e-04	11	54	2	22065784
Pubmed	Selective inhibition of spinal cord neurite outgrowth and cell survival by the Eph family ligand ephrin-A5.	EPHA6 EPHA3	1.29e-04	11	54	2	10559410
Pubmed	Endothelins are vascular-derived axonal guidance cues for developing sympathetic neurons.	ECE1 ECE2	1.29e-04	11	54	2	18401410
Pubmed	Ephrin/ephrin receptor expression during early stages of mouse inner ear development.	EPHB2 EPHA3	1.55e-04	12	54	2	21465626
Pubmed	Genetic analysis of genes involved in amyloid-β degradation and clearance in Alzheimer's disease.	ECE1 ECE2	1.55e-04	12	54	2	22027013
Pubmed	Eph-ephrin A system regulates murine blastocyst attachment and spreading.	EPHA6 EPHA3	1.83e-04	13	54	2	17039519
Pubmed	EphA family gene expression in the developing mouse neocortex: regional patterns reveal intrinsic programs and extrinsic influence.	EPHA6 EPHA3	1.83e-04	13	54	2	12528186
Pubmed	Ephrin Ligands and Eph Receptors Show Regionally Restricted Expression in the Developing Palate and Tongue.	EPHA6 EPHA3	2.13e-04	14	54	2	26941654
Pubmed	A role for the EphA family in the topographic targeting of vomeronasal axons.	EPHA6 EPHA3	2.13e-04	14	54	2	11222144
Pubmed	Localization of the muscle, liver, and brain glycogen phosphorylase genes on linkage maps of mouse chromosomes 19, 12, and 2, respectively.	PYGB PRNP	2.45e-04	15	54	2	2575583
Pubmed	Identification of SH3 domain proteins interacting with the cytoplasmic tail of the a disintegrin and metalloprotease 10 (ADAM10).	PACSIN1 PACSIN2	2.45e-04	15	54	2	25036101
Pubmed	No replication of genetic association between candidate polymorphisms and Alzheimer's disease.	ECE1 PRNP	2.80e-04	16	54	2	19889475
Pubmed	Eph receptors and ligands comprise two major specificity subclasses and are reciprocally compartmentalized during embryogenesis.	EPHB2 EPHA6	2.80e-04	16	54	2	8755474
Pubmed	A genomic atlas of mouse hypothalamic development.	EPHB2 GAD2 NCOA1 EPHA3	2.94e-04	205	54	4	20436479
Pubmed	The protein tyrosine kinase family of the human genome.	EPHB2 EPHA6 EPHA3	2.98e-04	83	54	3	11114734
Pubmed	Systematic analysis of candidate genes for Alzheimer's disease in a French, genome-wide association study.	DAPK1 PRNP	3.17e-04	17	54	2	20413850
Pubmed	Ephrin-B2 and EphB1 mediate retinal axon divergence at the optic chiasm.	EPHB2 EPHA3	3.17e-04	17	54	2	12971893
Pubmed	A Family of Vertebrate-Specific Polycombs Encoded by the LCOR/LCORL Genes Balance PRC2 Subtype Activities.	JARID2 EHMT1	3.56e-04	18	54	2	29628311
Pubmed	Identification and developmental analysis of genes expressed by dopaminergic neurons of the substantia nigra pars compacta.	JARID2 AKAP9 CSMD2	3.78e-04	90	54	3	15033168
Pubmed	Multiple roles of EPH receptors and ephrins in neural development.	EPHB2 EPHA3	4.42e-04	20	54	2	11256076
Pubmed	The ephrins and Eph receptors in neural development.	EPHB2 EPHA3	4.42e-04	20	54	2	9530499
Pubmed	Eph receptors and ephrins: effectors of morphogenesis.	EPHB2 EPHA3	4.42e-04	20	54	2	10207129
Pubmed	The Eph family receptors and ligands.	EPHB2 EPHA3	4.42e-04	20	54	2	9576626
Pubmed	TNF-α inhibits glucocorticoid receptor-induced gene expression by reshaping the GR nuclear cofactor profile.	TRAPPC11 EHMT1 NCOA1 IDH3B CSMD2 KPNA1	4.55e-04	638	54	6	31182584
Pubmed	Prediction of the coding sequences of unidentified human genes. XI. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.	FCHSD2 AKAP9 SYNE1	5.29e-04	101	54	3	9872452
Pubmed	Assessment of Alzheimer's disease case-control associations using family-based methods.	DAPK1 PRNP	5.36e-04	22	54	2	18830724
Pubmed	Zic2-dependent axon midline avoidance controls the formation of major ipsilateral tracts in the CNS.	EPHB2 EPHA6	5.86e-04	23	54	2	24360543
Pubmed	Intermediate phenotypes identify divergent pathways to Alzheimer's disease.	DAPK1 PRNP	6.94e-04	25	54	2	20574532
Pubmed	Effects of chronic ascariasis and trichuriasis on cytokine production and gene expression in human blood: a cross-sectional study.	RNASE2 MME	7.51e-04	26	54	2	21666788
Pubmed	Histone H3 lysine 9 methyltransferases, G9a and GLP are essential for cardiac morphogenesis.	EHMT1 EPHA3	7.51e-04	26	54	2	23892084
GeneFamily	Fibronectin type III domain containing\|Sterile alpha motif domain containing\|EPH receptors	EPHB2 EPHA6 EPHA3	3.07e-06	14	38	3	1095
GeneFamily	Rho GTPase activating proteins\|F-BAR domain containing	FCHSD2 PACSIN1 PACSIN2	1.47e-05	23	38	3	1288
GeneFamily	Fibronectin type III domain containing	EPHB2 EPHA6 PTPRJ EPHA3	3.45e-04	160	38	4	555
GeneFamily	Sterile alpha motif domain containing	EPHB2 EPHA6 EPHA3	8.31e-04	88	38	3	760
GeneFamily	ADAM metallopeptidase domain containing\|CD molecules	MRC1 PTPRJ MME PRNP	9.14e-03	394	38	4	471
Coexpression	GSE15330_HSC_VS_MEGAKARYOCYTE_ERYTHROID_PROGENITOR_DN	USP53 FCHSD2 SLC6A19 DNAJC7 TASOR2	2.08e-05	168	52	5	M7007
Coexpression	LAKE_ADULT_KIDNEY_C26_MESANGIAL_CELLS	USP53 FCHSD2 AKAP9 SYNE1 NCOA1	2.67e-05	177	52	5	M39245
Coexpression	GSE1460_CD4_THYMOCYTE_VS_THYMIC_STROMAL_CELL_UP	PIK3CD VTCN1 NCOA1 SPG11 EPB42	4.67e-05	199	52	5	M3478
Coexpression	GSE20366_EX_VIVO_VS_DEC205_CONVERSION_NAIVE_CD4_TCELL_DN	JARID2 FAM184B BRD4 PRNP KPNA1	4.67e-05	199	52	5	M4328
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_1\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	EPHB2 ABCA13 SYNE1 VTCN1 DAPK1	2.84e-06	183	54	5	cfae90c309622b5d499e62a3a8a8b9746478d28d
ToppCell	wk_08-11-Epithelial-PNS-COL20A1+_Schwann\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	USP53 FAM184B FAM78B CSMD2 PRNP	2.99e-06	185	54	5	abec2a49fe0f0fa4cba49347207a1ee317333657
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	EPHB2 ABCA13 SYNE1 VTCN1 DAPK1	3.41e-06	190	54	5	3fc9e18c7441c0ae8cda65753cc42d0520f4e116
ToppCell	nucseq\|World / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	JARID2 FCHSD2 PTPRJ DAPK1 EPB42	3.68e-06	193	54	5	779276e775cb2492e8dd36436295a536084a6415
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	GAD2 NETO1 PIK3CD DAPK1 ECE2	3.68e-06	193	54	5	010717ca052b6c8a525a43aaeffddea0d1113e63
ToppCell	saliva-Severe-critical_progression_d28-40-Myeloid-Macrophage-macrophage,_alveolar-Macro_c3-EREG\|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)	LRRC8C MRC1 RNASE2 DAPK1 PRNP	3.96e-06	196	54	5	80264c2fbd94418f981085fed7c5bdda1e6f404c
ToppCell	metastatic_Lymph_Node-Myeloid_cells-Alveolar_Mac\|Myeloid_cells / Location, Cell class and cell subclass	MRC1 LTA4H MME TECTA	2.59e-05	141	54	4	399380de5ea09e22fd128e3e55fffeffc4874c15
ToppCell	PBMC-Control-Myeloid-Neutrophil-Neutrophil-Neu_1\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	ABCA13 VTCN1 MME CFAP69	2.66e-05	142	54	4	191a13bba143ecdfc2bfd797c3ac191481388298
ToppCell	PBMC-Control-Myeloid-Neutrophil-Neutrophil-Neu_1\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	ABCA13 VTCN1 MME CFAP69	2.73e-05	143	54	4	b405dba9a83a99cc7b53ce71772bc52a0bbb0d4e
ToppCell	TCGA-Brain-Primary_Tumor-Low_Grade_Glioma-Astrocytoma-3\|TCGA-Brain / Sample_Type by Project: Shred V9	JARID2 FCHSD2 CSMD2 TASOR2	3.21e-05	149	54	4	768877bade04ca0321593b8470b5011ad8270431
ToppCell	E18.5-samps-Mesenchymal-Matrix_fibroblast-MatrixFB-A\|E18.5-samps / Age Group, Lineage, Cell class and subclass	GAD2 UNC13D MME PPM1K	4.67e-05	164	54	4	519ab4fe885dfe4c50846f346a062acc2cb44299
ToppCell	367C-Lymphocytic-NK_cells-NK_cell_B2\|NK_cells / Donor, Lineage, Cell class and subclass (all cells)	TRAPPC11 EHMT1 UNC13D ECE2	5.37e-05	170	54	4	c1f7f1bb8865e954bb499963d82bb51923d5d8d6
ToppCell	wk_15-18-Hematologic-Myeloid-pDC\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	FCHSD2 PACSIN1 PPM1K SLC9C2	5.75e-05	173	54	4	b571970e3ba88afc07041c5692ccfd85fc39e796
ToppCell	droplet-Liver-LIVER_HEP-30m-Myeloid-Kupffer_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MRC1 PTPRJ VTCN1 PYGB	6.14e-05	176	54	4	5e46a09a36b9645b1b1fcb0b64bd0898561af3a9
ToppCell	3'-Distal_airway-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophages-\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	MRC1 PYGB LTA4H MME	6.85e-05	181	54	4	166ff44fcc0a2943b7f485ea8a9c314964e013bb
ToppCell	systemic_lupus_erythematosus-treated-Myeloid-plasmacytoid_dendritic_cell-female\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	FCHSD2 PACSIN1 MME SLC9C2	7.00e-05	182	54	4	9bbe8062aa562dc3b9c299581faf6ebbcb72a9f7
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT_L6_FEZF2-Exc_L6_FEZF2_VWA2\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	EPHB2 EPHA6 MME TECTA	7.00e-05	182	54	4	72e65a23cd36085bc880087d3cae92395de918a1
ToppCell	systemic_lupus_erythematosus-treated-Myeloid-plasmacytoid_dendritic_cell\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	FCHSD2 PACSIN1 MME SLC9C2	7.00e-05	182	54	4	4602a98df7045e2c70b7560abfba9b444fbd5d30
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT_L6_FEZF2\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	EPHB2 EPHA6 MME TECTA	7.00e-05	182	54	4	05c167158815bf25d509df59ab386e1990712765
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_1\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	GAD2 EPHA6 NINL ECE2	7.15e-05	183	54	4	e3ffef2b57dc5b96466dccc9cd54ba326ccf378a
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_1\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	GAD2 EPHA6 NINL ECE2	7.45e-05	185	54	4	027020754dbf71b0034791f9a34ae795e3b85f81
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	GAD2 EPHA6 FAM78B ECE2	7.93e-05	188	54	4	8de5a07301f9b5984680c873e5a92395b5ed3dd3
ToppCell	droplet-Kidney-nan-3m-Epithelial-kidney_distal_convoluted_tubule_epithelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ABCA13 NINL PYGB DAPK1	8.10e-05	189	54	4	e127e3be626bc513e151d41812f0b7adb89d5da6
ToppCell	droplet-Kidney-nan-3m-Epithelial-Epcam_____kidney_distal_convoluted_tubule_epithelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ABCA13 NINL PYGB DAPK1	8.10e-05	189	54	4	ff637ae0afdb1fdc67451be7e1e4fe575fbcfff4
ToppCell	control-Myeloid-Immature_Neutrophils_1\|control / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs	RNASE2 ABCA13 SYNE1 LTA4H	8.26e-05	190	54	4	38e83337c70c8734b63f8589ba59e0f98603f94c
ToppCell	PBMC-Severe-Myeloid-Neutrophil-immature_Neutrophil\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	RNASE2 ABCA13 SYNE1 LTA4H	8.43e-05	191	54	4	6c1283d51a845cff67ed5e500f7e944165297b53
ToppCell	LV-08._Macrophage\|World / Chamber and Cluster_Paper	MRC1 PTPRJ PIK3CD DAPK1	8.43e-05	191	54	4	e7a0bc46ba9ba772636a583f3387748418e18832
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	EPHB2 VTCN1 PYGB DAPK1	8.43e-05	191	54	4	5a67ff17fb4b9eff641176dff07830c9cd73754e
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	EPHB2 VTCN1 PYGB DAPK1	8.43e-05	191	54	4	55ab2854a02cdcfc395e49870ccb7290b5e5471d
ToppCell	COVID-19-lung-Macrophage_PPARGhi_CD5Lhi\|lung / Disease (COVID-19 only), tissue and cell type	MRC1 DAPK1 LTA4H MME	8.43e-05	191	54	4	dab953682b8c9ed680a799161f837f792a7e4f33
ToppCell	RV-08._Macrophage\|World / Chamber and Cluster_Paper	MRC1 PTPRJ PIK3CD DAPK1	8.60e-05	192	54	4	a1b5dc5beb97a23729b97b54fb4574d10d8fbfb3
ToppCell	LV-08._Macrophage\|LV / Chamber and Cluster_Paper	MRC1 PTPRJ PIK3CD DAPK1	8.60e-05	192	54	4	7be12d580aaf2f2f1562203fcad3a44639b8c5a6
ToppCell	control-Myeloid-Immature_Neutrophils_1\|Myeloid / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs	RNASE2 ABCA13 SYNE1 LTA4H	8.60e-05	192	54	4	9f12b79d661ef0f57c2c924e8ecc24a46ea996d2
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	GAD2 NETO1 DAPK1 ECE2	8.60e-05	192	54	4	dc40ef2341e5d6a6d479f140e023fe1bf687928d
ToppCell	Somatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	GAD2 NETO1 PIK3CD DAPK1	8.78e-05	193	54	4	d1445b8bf2bab36e1a326ddb2a528151db016c7d
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST-Inh_L4-6_SST_MTHFD2P6\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	GAD2 NETO1 PIK3CD DAPK1	8.78e-05	193	54	4	2c15186d15545804cc262da9137ab825609d4b2c
ToppCell	RV-08._Macrophage\|RV / Chamber and Cluster_Paper	MRC1 PTPRJ PIK3CD DAPK1	8.78e-05	193	54	4	12bf98a280f87e4d8f0c6887dfc855da72e47ac1
ToppCell	10x3'2.3-week_14-16-Myeloid_DC-DC-pDC\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	FCHSD2 AKAP9 PACSIN1 PPM1K	8.78e-05	193	54	4	2c35aadc397e7e365c3daf8017ae1d3bd045f305
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	PTPRJ SYNE1 VTCN1 DAPK1	8.78e-05	193	54	4	f42a0f02ed00fe1bb833ff0a0640d9131bca89bd
ToppCell	droplet-Kidney-nan-21m-Epithelial-Epcam_____kidney_distal_convoluted_tubule_epithelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ABCA13 NINL PYGB DAPK1	8.78e-05	193	54	4	b397c14ac1e34c6be3f25d4417d200bc518d3048
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	GAD2 NETO1 PIK3CD DAPK1	8.78e-05	193	54	4	3ed46f5a7419ec4eddbd0df0d9b5f53aa486198b
ToppCell	droplet-Kidney-nan-21m-Epithelial-kidney_distal_convoluted_tubule_epithelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ABCA13 NINL PYGB DAPK1	8.78e-05	193	54	4	241a60d1f0d5832638fb3e1e4b7afa7387ea3c75
ToppCell	BAL-Mild-Myeloid-MoAM-MoAM3-\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	EPHB2 MRC1 RNASE2 LTA4H	8.78e-05	193	54	4	93ba635ed69fec9286fe7636b9d258f3d93a22c3
ToppCell	BAL-Mild-Myeloid-MoAM-MoAM3\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	EPHB2 MRC1 RNASE2 LTA4H	8.78e-05	193	54	4	6dfdeb793cb5ad6412b6f808b5687a4e74b6ec65
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	PTPRJ SYNE1 VTCN1 DAPK1	8.78e-05	193	54	4	42df7ed37d11fb542b4d1d714b6f87ae8e1396a6
ToppCell	BAL-Mild-Myeloid-MoAM-MoAM3-\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	EPHB2 MRC1 RNASE2 LTA4H	8.95e-05	194	54	4	e455cb469157c044126f9b0b308957d4ee1e608b
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	PTPRJ ABCA13 SYNE1 DAPK1	8.95e-05	194	54	4	e577d9e88390b36b5a09b97fe1026089892275a3
ToppCell	CTRL-Myeloid-Alveolar_Macrophage\|CTRL / Disease state, Lineage and Cell class	MRC1 DAPK1 LTA4H MME	8.95e-05	194	54	4	be69b20afa915978c4cf2feb0bb21ab7c1f301a5
ToppCell	BAL-Mild-Myeloid-MoAM-MoAM3\|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)	EPHB2 MRC1 RNASE2 LTA4H	8.95e-05	194	54	4	e0cfd18a7ea2251163d61312b9397f8a518c8c51
ToppCell	368C-Myeloid-Macrophage-M2-like_Macrophage_(MARCO_negative)\|Macrophage / Donor, Lineage, Cell class and subclass (all cells)	EPHB2 USP53 MRC1 SYNE1	8.95e-05	194	54	4	58046894446cb250814252a23f60fdd59c114d77
ToppCell	severe-Myeloid-Immature_Neutrophils_1\|severe / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs	RNASE2 ABCA13 SYNE1 LTA4H	9.13e-05	195	54	4	becad890a420267ca41e98e61a8da343b51e1945
ToppCell	Mild_COVID-19-Myeloid-MoAM3\|Mild_COVID-19 / Disease group,lineage and cell class （2021.01.30）	EPHB2 MRC1 RNASE2 LTA4H	9.32e-05	196	54	4	9faad17aa0b6af5a8ec2dadf7d70b9209d658072
ToppCell	PND01-03-samps-Mesenchymal-Matrix_fibroblast\|PND01-03-samps / Age Group, Lineage, Cell class and subclass	GAD2 MME PPM1K EPHA3	9.32e-05	196	54	4	54f4cf778f95a9ff662e5c7520916a25e605bf95
ToppCell	Biopsy_Other_PF-Immune-pDCs\|Biopsy_Other_PF / Sample group, Lineage and Cell type	FCHSD2 PACSIN1 PPM1K SLC9C2	9.50e-05	197	54	4	598a130eb7afb1bb95da64a964218362627feb49
ToppCell	5'-Airway_Nasal-Epithelial-Airway_ciliated\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	AKAP9 ABCA13 SYNE1 CFAP69	9.50e-05	197	54	4	91637bdeab85024b5a02d1066f76cb803a2d6420
ToppCell	5'-Airway_Nasal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	AKAP9 ABCA13 SYNE1 CFAP69	9.50e-05	197	54	4	22c87dd15dc57bd0aa98a204c9fc9b3b9b573b45
ToppCell	COVID-19-kidney-Macrophages\|COVID-19 / Disease (COVID-19 only), tissue and cell type	JARID2 MRC1 PTPRJ DAPK1	9.50e-05	197	54	4	3912301018d0863144dcfac8d1fa8adc081748d7
ToppCell	3'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.2\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	AKAP9 SYNE1 CFAP69 SLC9C2	9.50e-05	197	54	4	74a2c6cb8fcfe53dd9a2b36492a16c58f38e51c9
ToppCell	5'-Airway_Nasal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.0.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	AKAP9 ABCA13 SYNE1 CFAP69	9.50e-05	197	54	4	3bbf068d2ad8196fbc85d3f311a7c54c9aece856
ToppCell	5'-Airway_Nasal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	AKAP9 ABCA13 SYNE1 CFAP69	9.50e-05	197	54	4	87db09f341e2b20eb6e1c3e917cb5c960387b3e9
ToppCell	Parenchymal-NucSeq-Epithelial-Epi_airway_basal-Suprabasal\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	ABCA13 VTCN1 ECE1 EPB42	9.69e-05	198	54	4	28ada093cec552262731194a04a4b9ff93186c3b
ToppCell	severe-pDC\|severe / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	FCHSD2 PACSIN1 DAPK1 SLC9C2	9.69e-05	198	54	4	22da4a29b9ff8b94d98bc69b4632a2a58d5dd9e6
ToppCell	normal_Lung-Fibroblasts-COL13A1+_matrix_FBs\|Fibroblasts / Location, Cell class and cell subclass	MLH3 AKAP9 MME PPM1K	9.69e-05	198	54	4	e0e47cf65774191981840b22905b2094b95abe0f
ToppCell	Tracheal-10x3prime_v2-Immune_Myeloid-Macrophage_alveolar-Macro_alv_MT\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	MRC1 RNASE2 PIK3CD UNC13D	9.88e-05	199	54	4	4e0b73d88b1345ec63a9e5629762341e75beb47f
ToppCell	Neuronal-Inhibitory-iB-iB_4(SST)-B3GAT2\|Neuronal / cells hierarchy compared to all cells using T-Statistic	MRC1 GAD2 PIK3CD DAPK1	1.01e-04	200	54	4	858421b91f5207b7934b5c219752cb9322a3da31
ToppCell	COVID-19-COVID-19_Severe-Myeloid-immature_Neutrophil\|COVID-19_Severe / Disease, condition lineage and cell class	RNASE2 ABCA13 SYNE1 LTA4H	1.01e-04	200	54	4	cbe667eda1af222467df8bfa157aa22df488f133
ToppCell	Neuronal-Inhibitory-iA-iA_1(SST_PAX6)\|Neuronal / cells hierarchy compared to all cells using T-Statistic	GAD2 EPHA6 NINL ECE2	1.01e-04	200	54	4	d0167f96314be78b6d867bbcc6e4396071d931b8
ToppCell	Neuronal-Inhibitory-iB-iB_4(SST)-B3GAT2-\|Neuronal / cells hierarchy compared to all cells using T-Statistic	MRC1 GAD2 PIK3CD DAPK1	1.01e-04	200	54	4	a7022762c1d8aedb7b3e9605873b1e68b9907b35
ToppCell	Neuronal-Inhibitory-iB-iB_4(SST)-B3GAT2--L4-6\|Neuronal / cells hierarchy compared to all cells using T-Statistic	MRC1 GAD2 PIK3CD DAPK1	1.01e-04	200	54	4	2131c8e7fa054b79906eaf60536da892438b09cd
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW23-Neuronal\|GW23 / Sample Type, Dataset, Time_group, and Cell type.	GAD2 AKAP9 EPHA3	2.16e-04	96	54	3	56e993d37b7958abe56682422536045550e29b41
ToppCell	(09)_Ionocytes-(4)_1wkpi\|(09)_Ionocytes / shred by cell type and Timepoint	PYGB LTA4H	3.22e-04	22	54	2	b35fb230042a027b10ef3e7ef09bf13ea1cdc506
ToppCell	Fetal_brain-fetalBrain_Zhong_nature-GW23-Neuronal\|GW23 / Sample Type, Dataset, Time_group, and Cell type.	GAD2 AKAP9 EPHA3	3.40e-04	112	54	3	9c3fb470708e76a8f8a3cb9aa17ab130c60fee11
ToppCell	PBMC-Mild-Myeloid-Neutrophil-immature_Neutrophil-Neu_4\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	ABCA13 CSMD2 SLC9C2	4.79e-04	126	54	3	69b2525b92d1c7c35b21cc701f5fa52a9c1b94bb
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW10-Neuronal-Interneuron\|GW10 / Sample Type, Dataset, Time_group, and Cell type.	GAD2 NETO1 EPHA3	4.79e-04	126	54	3	ec445ec097c9c45cd47b8cfa8c140df5b298695e
ToppCell	PBMC-Mild-Myeloid-Neutrophil-immature_Neutrophil-Neu_4\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	ABCA13 CSMD2 SLC9C2	4.79e-04	126	54	3	6cb89754010d64875e115da6c5805efac7a4a82d
ToppCell	Control-Neu_1\|Control / 5 Neutrophil clusters in COVID-19 patients	UNC13D MME	5.24e-04	28	54	2	eb8d8303c1a8f8f8cf9f8c2180406c06624690af
ToppCell	PBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c13-HAVCR2\|Mild-Moderate_convalescent_d36-51 / Compartment, severity and other cell annotations on 10x 3' data (130k)	PACSIN1 NCOA1 MME	5.86e-04	135	54	3	641d42a005ff61f21e6cda02bfbd0bd1d4ba2faa
ToppCell	TCGA-Brain-Primary_Tumor-Low_Grade_Glioma-Oligodendroglioma-3\|TCGA-Brain / Sample_Type by Project: Shred V9	FCHSD2 VTCN1 TASOR2	5.86e-04	135	54	3	b128596653a5e3b64ed7f657bbfeda35438e2e48
ToppCell	TCGA-Brain-Primary_Tumor-Low_Grade_Glioma-Oligoastrocytoma-3\|TCGA-Brain / Sample_Type by Project: Shred V9	JARID2 DAPK1 CSMD2	5.86e-04	135	54	3	3351e8b9e417397c5fa9f856184ff24ce1a27242
ToppCell	control-Myeloid-CD14_Monocytes_3\|Myeloid / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs	EPHB2 RNASE2 CFAP69	6.25e-04	138	54	3	74087d94f993b9efa4a6e1ee35451a27cf341c4b
ToppCell	(08)_Brush+PNEC-(2)_GFP_FOXI1\|(08)_Brush+PNEC / shred by cell type by condition	USP53 AKAP9 BRD4	6.25e-04	138	54	3	817e3f639604ea95adae01e8685ffaa2e0aff7a8
ToppCell	control-Myeloid-CD14_Monocytes_3\|control / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs	EPHB2 RNASE2 CFAP69	6.25e-04	138	54	3	683cae06f710061d7d74c2f75eb511a2af55bacf
ToppCell	facs-Lung-Endomucin-24m-Endothelial-Capillary_Type_1_Cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EPHA6 ABCA13 TECTA	7.21e-04	145	54	3	96712c68ab759d7ade0d912581a1a7c25dc6def8
ToppCell	kidney_cells-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_1_/_Segment_2\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	PTPRJ SLC6A19 PRNP	7.21e-04	145	54	3	47a3bb973a508d3097213a2d86ad1ce697af9bae
ToppCell	COVID-19-kidney-Technical/muscle_(PCT)\|kidney / Disease (COVID-19 only), tissue and cell type	EPHA6 ABCA13 CSMD2	7.35e-04	146	54	3	c55f1bdb6ac43b4118cb27ea7c879527e1afcbab
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	EPHB2 ABCA13 SLC6A19	8.42e-04	153	54	3	499670e716fc85ce76630fc813cec86f8419f2a1
ToppCell	facs-Marrow-B-cells-24m-Myeloid-granulocytopoietic_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RNASE2 ABCA13 SYNE1	8.58e-04	154	54	3	71ffc23a2e02e27cabbdbeaa622e59e9f4a4cd9d
ToppCell	facs-Marrow-B-cells-24m-Myeloid-granulocytopoietic_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RNASE2 ABCA13 SYNE1	8.58e-04	154	54	3	46155f36d3983f637b55d7525b675c8828f6ab2e
ToppCell	metastatic_Lymph_Node-Myeloid_cells-Alveolar_Mac\|metastatic_Lymph_Node / Location, Cell class and cell subclass	MRC1 LTA4H MME	8.74e-04	155	54	3	03fd443740272dcb547e39deaf7ae89b8307f241
ToppCell	PCW_13-14-Neuronal-Neuronal_SCP-neuro_proliferating_SCP1_(1)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	FAM78B VTCN1 CSMD2	8.91e-04	156	54	3	8353f98e7d393d4299ed1da8f66cfbc7176df1b5
ToppCell	facs-Spleen-nan-24m-Myeloid\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RNASE2 ABCA13 SYNE1	8.91e-04	156	54	3	034d4359359a44c205c6931f38a375271ac2752b
ToppCell	facs-Spleen-nan-24m-Myeloid-nan\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RNASE2 ABCA13 SYNE1	8.91e-04	156	54	3	2a4dac4100c0339aad4905b8eaca6e8fe806718b
ToppCell	facs-Spleen-nan-24m-Myeloid-granulocyte\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RNASE2 ABCA13 SYNE1	8.91e-04	156	54	3	21267718d3a3dc19988663b6846aed8bb3eae836
ToppCell	PBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51-Myeloid-Macrophage-macrophage,_alveolar-Macro_c2-CCL3L1\|Mild-Moderate_convalescent_d36-51 / Compartment, severity and other cell annotations on 10x 3' data (130k)	EPHA6 DAPK1 TECTA	9.07e-04	157	54	3	a98d06cef80bfe8481b0940abce2b29675e45812
ToppCell	PND28-Immune-Immune_Myeloid-Monocytic-Macrophage-AM-AM_mature\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MRC1 RNASE2 DAPK1	9.24e-04	158	54	3	6811dc4f101dfa9a9cc13d949760d43aa522bf3b
ToppCell	COVID-19-kidney-Technical/muscle_(Mes)\|kidney / Disease (COVID-19 only), tissue and cell type	EPHA6 CSMD2 EPHA3	9.41e-04	159	54	3	5335cbcdeaf2bbd0268bbfe0e45c8c0d288e640d
ToppCell	frontal_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Pygm_C1ql1\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	FAM184B GAD2 TECTA	9.76e-04	161	54	3	3b5d7a3dab479c6959a428f3954dedd989900276
ToppCell	Adult-Mesenchymal-myofibroblast_cell-D175\|Adult / Lineage, Cell type, age group and donor	FSIP2 CSMD2 EPHA3	9.76e-04	161	54	3	048b7dc00746987a24bf870d4d278c4183eb04a2
ToppCell	TCGA-Brain-Primary_Tumor-Low_Grade_Glioma-Oligoastrocytoma\|TCGA-Brain / Sample_Type by Project: Shred V9	FCHSD2 DAPK1 PPM1K	9.76e-04	161	54	3	347edb0de10850b7d16c40945751033289289c9b
ToppCell	frontal_cortex-Neuronal-GABAergic_neuron-Sst\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	GAD2 NETO1 ECE2	9.76e-04	161	54	3	dccb61d5e17a8f1c6d1fc146ee389f567659a0f0
Drug	2-nitroaniline	EPHB2 PACSIN1 ECE1 DNAJC7 PACSIN2 PRNP	6.68e-07	139	51	6	CID000006946
Drug	quinolinic acid	EPHB2 GAD2 PACSIN1 DNAJC7 PACSIN2 PRNP	2.92e-06	179	51	6	CID000001066
Drug	CGS 26303	MME ECE1	4.92e-06	2	51	2	ctd:C089987
Drug	1r1h	LTA4H MME	4.92e-06	2	51	2	CID005478838
Drug	N-[3-[(1-Aminoethyl)(Hydroxy)Phosphoryl]-2-(1,1'-Biphenyl-4-Ylmethyl)Propanoyl]Alanine	LTA4H MME	4.92e-06	2	51	2	DB02062
Drug	CGS 34043	MME ECE1	4.92e-06	2	51	2	ctd:C404931
Drug	CGS 35066	MME ECE1	4.92e-06	2	51	2	ctd:C404932
Drug	Nadolol [42200-33-9]; Down 200; 13uM; HL60; HT_HG-U133A	EPHB2 BRD4 NCOA1 ECE1 CFAP69 EPHA3	5.52e-06	200	51	6	3020_DN
Drug	benzoquinone	PACSIN1 SYNE1 POLG DNAJC7 PACSIN2 PRNP	7.11e-06	209	51	6	CID000004650
Drug	daglutril	MME ECE1 ECE2	1.18e-05	20	51	3	CID003038505
Drug	UK 79300	EHMT1 MME ECE1	2.35e-05	25	51	3	CID000122116
Drug	p181	SYNE1 ECE1	2.94e-05	4	51	2	CID000012208
Drug	ZD4054	MME ECE1	2.94e-05	4	51	2	ctd:C511404
Drug	NSC350593	RNASE2 PTPRJ PIK3CD UNC13D LTA4H MME	2.97e-05	269	51	6	CID000004364
Drug	V0509	PACSIN1 PIK3CD PYGB DNAJC7 PACSIN2 PRNP	3.16e-05	272	51	6	CID000102191
Drug	Kelatorphan	LTA4H MME ECE1	4.12e-05	30	51	3	CID000123982
Drug	lithocholyltaurine	PACSIN1 PYGB DNAJC7 PACSIN2 PRNP	4.47e-05	175	51	5	CID000010595
Drug	3-nitropropionic acid	GAD2 PACSIN1 DNAJC7 PACSIN2 PRNP	4.85e-05	178	51	5	CID000001678
Drug	4-acetylpyridine	GAD2 SYNE1	4.90e-05	5	51	2	CID000014282
Drug	cystamine	PACSIN1 NCOA1 DNAJC7 PACSIN2 PRNP	5.25e-05	181	51	5	CID000002915
Drug	vorinostat	PACSIN1 NCOA1 DNAJC7 PACSIN2 PRNP KPNA1	7.01e-05	314	51	6	CID000005311
Drug	phenylquinone	SYNE1 LTA4H MME	7.18e-05	36	51	3	CID000009688
Drug	AC1L9QEM	SYNE1 LTA4H	7.34e-05	6	51	2	CID000452587
Drug	Cyclopentolate hydrochloride [5870-29-1]; Up 200; 12.2uM; HL60; HT_HG-U133A	EPHB2 GAD2 MLH3 EHMT1 TECTA	8.22e-05	199	51	5	6132_UP
Drug	AC1NSJV8	MME ECE1 ECE2	9.14e-05	39	51	3	CID005311032
Drug	N-methyl-DL-aspartic acid	EPHB2 GAD2 AKAP9 NETO1 PIK3CD DAPK1 TECTA EPHA3	9.60e-05	655	51	8	CID000004376
Drug	NSC-364372	AKAP9 PACSIN1 NCOA1 DNAJC7 PACSIN2 PRNP KPNA1	9.69e-05	484	51	7	CID000435143
Drug	DB07328	PACSIN1 POLG DNAJC7 PACSIN2 PRNP	1.01e-04	208	51	5	CID011840913
Drug	CGS 35601	MME ECE1	1.03e-04	7	51	2	ctd:C511403
Drug	phosphonic acid	SYNE1 LTA4H MME ECE1	1.04e-04	109	51	4	CID003084169
Drug	AC1NB8R3	PACSIN1 MME DNAJC7 PACSIN2 PRNP	1.13e-04	213	51	5	CID004489307
Drug	neotrehalose	PACSIN1 PYGB DNAJC7 PACSIN2 PRNP	1.16e-04	214	51	5	CID000001143
Drug	AC1L1FHZ	MRC1 PACSIN1 DNAJC7 PACSIN2 PRNP	1.18e-04	215	51	5	CID000003244
Drug	DIBAH	SYNE1 PYGB	1.37e-04	8	51	2	CID000014487
Disease	cerebellar ataxia (is_implicated_in)	SYNE1 POLG	3.15e-05	5	53	2	DOID:0050753 (is_implicated_in)
Disease	Malignant neoplasm of prostate	EPHB2 PIK3CD BRD4 NCOA1 UNC13D MME PRNP	1.12e-04	616	53	7	C0376358
Disease	Hereditary Non-Polyposis Colon Cancer Type 2	MLH3 PTPRJ	5.31e-04	19	53	2	C1333991
Disease	Colorectal cancer, hereditary nonpolyposis, type 1	MLH3 PTPRJ	5.31e-04	19	53	2	C2936783
Disease	brain age measurement	EEF1AKMT4-ECE2 ECE2	5.89e-04	20	53	2	EFO_0010602
Disease	Prostatic Neoplasms	PIK3CD BRD4 NCOA1 UNC13D MME PRNP	8.06e-04	616	53	6	C0033578
Disease	response to venlafaxine	POLG CSMD2	9.25e-04	25	53	2	EFO_0006328
Disease	Hereditary Nonpolyposis Colorectal Neoplasms	MLH3 PTPRJ	1.00e-03	26	53	2	C0009405
Disease	Colorectal cancer	MLH3 PTPRJ	1.08e-03	27	53	2	cv:C0346629
Disease	Hereditary non-polyposis colorectal cancer syndrome	MLH3 PTPRJ	1.08e-03	27	53	2	C1112155
Disease	COLORECTAL CANCER	MLH3 PTPRJ	1.08e-03	27	53	2	114500
Disease	Neoplasm of the large intestine	MLH3 PTPRJ	1.08e-03	27	53	2	cv:C0009404
Disease	Hereditary Nonpolyposis Colorectal Cancer	MLH3 PTPRJ	1.25e-03	29	53	2	C1333990
Disease	colorectal cancer (is_implicated_in)	MLH3 PTPRJ PIK3CD	1.36e-03	121	53	3	DOID:9256 (is_implicated_in)
Disease	Huntington's disease (implicated_via_orthology)	PACSIN1 PACSIN2	1.52e-03	32	53	2	DOID:12858 (implicated_via_orthology)
Disease	hypertension (implicated_via_orthology)	PTPRJ MME ECE1	1.59e-03	128	53	3	DOID:10763 (implicated_via_orthology)
Disease	Polyarthritis, Juvenile, Rheumatoid Factor Positive	FCHSD2 DAPK1 PACSIN2	1.70e-03	131	53	3	C4704862
Disease	Polyarthritis, Juvenile, Rheumatoid Factor Negative	FCHSD2 DAPK1 PACSIN2	1.70e-03	131	53	3	C4552091
Disease	Juvenile arthritis	FCHSD2 DAPK1 PACSIN2	1.70e-03	131	53	3	C3495559
Disease	Juvenile psoriatic arthritis	FCHSD2 DAPK1 PACSIN2	1.70e-03	131	53	3	C3714758
Disease	neuroimaging measurement, brain volume measurement	EEF1AKMT4-ECE2 MRC1 PYGB EPHA3	1.74e-03	286	53	4	EFO_0004346, EFO_0006930

Protein segments in the cluster

Peptide	Gene	Start	Entry
VEVDCNMFQNLTNYK	EPB42	666	P16452
MSLQQFVYDVQDQLN	DAPK1	986	P53355
NIDQSQCNEMYINSS	AKAP9	56	Q99996
CQQEQHYFNEMKLSQ	AKAP9	1481	Q99996
ETQYQFQAQLMLICD	CSMD2	2611	Q7Z408
NAQECIQDFNTMFTN	BRD4	121	O60885
IQACNQMEFFNTYSD	FAM78B	71	Q5VT40
CEVAQYVNMQESFQN	ABCA13	651	Q86UQ4
YEMQNSNECKRNFVA	NETO1	221	Q8TDF5
NFMVNSQEICDFVNQ	PPM1K	301	Q8N3J5
MQEVYNFNAINNSEI	LTA4H	521	P09960
QNCNQMHASYLFQQD	GAD2	416	Q05329
MVQTEDQYVFLNQCV	PTPRJ	1281	Q12913
QMQQALEQCTSNYRE	FAM184B	611	Q9ULE4
MDQCTYFNESLIQNL	FSIP2	3126	Q5CZC0
NHTACMEEQYNQYQV	ECE2	681	P0DPD6
ENMNTIRTYQVCNVF	EPHB2	51	P29323
QEACNNILDSYEMFN	MLH3	391	Q9UHC1
SASNFKEQSQCMVYQ	MME	611	P08473
RENFQDLMQYCAQDV	POLG	386	P54098
PQYMENMEQVFEQCQ	PACSIN1	221	Q9BY11
QYMENMEQVFEQCQQ	PACSIN2	221	Q9UNF0
ACMEEQYNQYQVNGE	EEF1AKMT4-ECE2	756	P0DPD8
DNCCMQLVQNPYQFD	IDH3B	251	O43837
QQMGYNCFSLENQET	CPHXL2	146	A0A1W2PPK0
NGCMQCYLQFNLENE	GPR32P1	186	Q8NGA4
QDVNQDNYIDAFECM	FUT10	376	Q6P4F1
RTYQVCNVMDHSQNN	EPHA3	66	P29320
QAQQEFKNANAVMEY	DNAJC7	131	Q99615
QTECMVEQYSNYSVN	ECE1	641	P42892
QVAQSRMNICENYKN	FCHSD2	96	O94868
SQACQDMQNEQKVYA	CFAP69	806	A5D8W1
QYLLSNGQMDVNCQD	EHMT1	856	Q9H9B1
CYLSMVVQENENVVF	JARID2	1146	Q92833
HTYQVCNVMEPNQNN	EPHA6	71	Q9UF33
NFANEDENCVTMYSN	MRC1	891	P22897
TQENFVDMQQRCNAS	SLC6A19	356	Q695T7
AIQQCNIMQEAVVQY	SYNE1	5726	Q8NF91
NIMQEAVVQYEQYEQ	SYNE1	5731	Q8NF91
MVNNFSQAEAVELCY	TAAR9	1	Q96RI9
QQQYIFQQCEAPMEG	KPNA1	521	P52294
NQEACQRYEVMQCFT	NCOA1	211	Q15788
ACSEMEVLNRQNQNY	NINL	1131	Q9Y2I6
TSQQCTNAMQVINNY	RNASE2	46	P10153
QQQNIMDQCYFENSL	USP53	881	Q70EK8
TVDVINQNTSCNNYM	SPG11	921	Q96JI7
NELQFSQYAAMCDNV	TECTA	1666	O75443
VSFNNQEYNQFCVIE	TRAPPC11	626	Q7Z392
ADYEAYMQCQAQVDQ	PYGB	776	P11216
EAYVFTCINQTAEQQ	PIK3CD	66	O00329
MDEYSNQNNFVHDCV	PRNP	166	P04156
RFQNCVMFNQAYVET	SLC9C2	1016	Q5TAH2
TQEDQNFICSYNNEV	TASOR2	906	Q5VWN6
ELCYMNTNLVQENFS	UNC13D	801	Q70J99
NVTINNTYSCMIEND	VTCN1	216	Q7Z7D3
TDLDLQQYSFINQMC	LRRC8C	101	Q8TDW0