Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionhistone H4K20me methyltransferase activity

KMT5B KMT5C

8.09e-054742GO:0140941
GeneOntologyMolecularFunctionhistone H4K20 monomethyltransferase activity

KMT5B KMT5C

2.01e-046742GO:0140944
GeneOntologyBiologicalProcessnegative regulation of cell cycle

HHEX CEBPA PTPRK RB1 E2F7 ZNF207 CDT1 TEX14 TP53BP2

2.95e-05464719GO:0045786
GeneOntologyBiologicalProcessattachment of spindle microtubules to kinetochore

RB1 ZNF207 CDT1 TEX14

4.14e-0556714GO:0008608
GeneOntologyCellularComponentchromosomal region

KMT5B KMT5C ZNF207 CDT1 TEX14 TEP1 ZNF692 XRCC6 DNMT1

1.55e-05421739GO:0098687
GeneOntologyCellularComponentchromosome, centromeric region

KMT5B KMT5C ZNF207 CDT1 TEX14 ZNF692 DNMT1

5.02e-05276737GO:0000775
GeneOntologyCellularComponentcondensed chromosome, centromeric region

KMT5B KMT5C ZNF207 CDT1 TEX14 ZNF692

5.84e-05193736GO:0000779
GeneOntologyCellularComponentRb-E2F complex

CEBPA RB1

1.79e-046732GO:0035189
GeneOntologyCellularComponentcondensed chromosome

KMT5B KMT5C ZNF207 CDT1 TEX14 ZNF692

7.13e-04307736GO:0000793
DomainSAM_MT43_SUVAR420_2

KMT5B KMT5C

1.38e-052702PS51570
DomainHist-Lys_N-MTase_Suvar4-20

KMT5B KMT5C

1.38e-052702IPR025790
DomainATPase_dyneun-rel_AAA

VWA8 DNAH1

1.22e-0314702IPR011704
DomainAAA_5

VWA8 DNAH1

1.22e-0314702PF07728
DomainCupredoxin

EFNB2 PADI3

3.05e-0322702IPR008972
Domainfn3

PTPRK PTPRO ROS1 FLRT3

3.21e-03162704PF00041
DomainC2_dom

SYT3 TNS2 UNC13D PLA2G4F

3.35e-03164704IPR000008
Domain-

PTPRK PTPRO TNS2

4.99e-03927033.90.190.10
DomainFN3

PTPRK PTPRO ROS1 FLRT3

5.14e-03185704SM00060
DomainProt-tyrosine_phosphatase-like

PTPRK PTPRO TNS2

6.12e-0399703IPR029021
DomainVWF_A

VWA8 XRCC6 ITIH5

6.12e-0399703IPR002035
DomainFN3

PTPRK PTPRO ROS1 FLRT3

6.63e-03199704PS50853
DomainFN3_dom

PTPRK PTPRO ROS1 FLRT3

7.86e-03209704IPR003961
DomainPTPc

PTPRK PTPRO

8.03e-0336702SM00194
PathwayBIOCARTA_TEL_PATHWAY

RB1 TEP1 XRCC6

3.10e-0517523MM1508
PathwayBIOCARTA_TEL_PATHWAY

RB1 TEP1 XRCC6

3.10e-0517523M10401
PathwayPID_RB_1PATHWAY

CEBPA RB1 MITF DNMT1

9.44e-0565524M279
Pubmed

The retinoblastoma protein regulates pericentric heterochromatin.

RB1 KMT5B KMT5C

9.25e-09374316612004
Pubmed

Loss of DNA methylation and histone H4 lysine 20 trimethylation in human breast cancer cells is associated with aberrant expression of DNA methyltransferase 1, Suv4-20h2 histone methyltransferase and methyl-binding proteins.

KMT5B KMT5C DNMT1

3.69e-08474316322686
Pubmed

Role of the RB1 family in stabilizing histone methylation at constitutive heterochromatin.

RB1 KMT5B KMT5C

3.22e-07774315750587
Pubmed

Dephosphorylated C/EBPalpha accelerates cell proliferation through sequestering retinoblastoma protein.

CEBPA RB1

4.47e-06274215684384
Pubmed

Suv4-20h deficiency results in telomere elongation and derepression of telomere recombination.

KMT5B KMT5C

4.47e-06274217846168
Pubmed

The SUV4-20 inhibitor A-196 verifies a role for epigenetics in genomic integrity.

KMT5B KMT5C

4.47e-06274228114273
Pubmed

CD74-ROS1 G2032R mutation transcriptionally up-regulates Twist1 in non-small cell lung cancer cells leading to increased migration, invasion, and resistance to crizotinib.

CD74 ROS1

4.47e-06274229477381
Pubmed

Preferential dimethylation of histone H4 lysine 20 by Suv4-20.

KMT5B KMT5C

4.47e-06274218296440
Pubmed

RB maintains quiescence and prevents premature senescence through upregulation of DNMT1 in mesenchymal stromal cells.

RB1 DNMT1

4.47e-06274225455074
Pubmed

Suv4-20h abrogation enhances telomere elongation during reprogramming and confers a higher tumorigenic potential to iPS cells.

KMT5B KMT5C

4.47e-06274222022429
Pubmed

Comparative analyses of SUV420H1 isoforms and SUV420H2 reveal differences in their cellular localization and effects on myogenic differentiation.

KMT5B KMT5C

4.47e-06274221206904
Pubmed

Crystal structures of the human histone H4K20 methyltransferases SUV420H1 and SUV420H2.

KMT5B KMT5C

4.47e-06274224396869
Pubmed

CD74-ROS1 L2026M mutant enhances autophagy through the MEK/ERK pathway to promote invasion, metastasis and crizotinib resistance in non-small cell lung cancer cells.

CD74 ROS1

4.47e-06274238148635
Pubmed

Mouse oocyte meiosis is disturbed by knockdown of Suv4-20h.

KMT5B KMT5C

4.47e-06274222951141
Pubmed

The retinoblastoma gene product interacts with maintenance human DNA (cytosine-5) methyltransferase and modulates its activity.

RB1 DNMT1

4.47e-06274211847125
Pubmed

A novel route to product specificity in the Suv4-20 family of histone H4K20 methyltransferases.

KMT5B KMT5C

4.47e-06274224049080
Pubmed

C/EBPα mediates the growth inhibitory effect of progestins on breast cancer cells.

CEBPA PGR

4.47e-06274231373033
Pubmed

Histone H4K20 tri-methylation at late-firing origins ensures timely heterochromatin replication.

KMT5B KMT5C

4.47e-06274228778956
Pubmed

DNMT1-interacting RNAs block gene-specific DNA methylation.

CEBPA DNMT1

4.47e-06274224107992
Pubmed

SUV4-20 activity in the preimplantation mouse embryo controls timely replication.

KMT5B KMT5C

4.47e-06274227920088
Pubmed

The atypical E2F family member E2F7 couples the p53 and RB pathways during cellular senescence.

RB1 E2F7

1.34e-05374222802529
Pubmed

FSHD muscular dystrophy region gene 1 binds Suv4-20h1 histone methyltransferase and impairs myogenesis.

KMT5B KMT5C

1.34e-05374223720823
Pubmed

The oncogenic lung cancer fusion kinase CD74-ROS activates a novel invasiveness pathway through E-Syt1 phosphorylation.

CD74 ROS1

1.34e-05374222659450
Pubmed

Progesterone receptor B recruits a repressor complex to a half-PRE site of the estrogen receptor alpha gene promoter.

NCOR1 PGR

1.34e-05374219147702
Pubmed

Synergistically enhanced CYP2B6 inducibility between a polymorphic mutation in CYP2B6 promoter and pregnane X receptor activation.

CYP2B6 CEBPA

1.34e-05374220624854
Pubmed

The Suv420h histone methyltransferases regulate PPAR-γ and energy expenditure in response to environmental stimuli.

KMT5B KMT5C

1.34e-05374231001581
Pubmed

Direct involvement of retinoblastoma family proteins in DNA repair by non-homologous end-joining.

RB1 XRCC6

1.34e-05374225818292
Pubmed

The Role of DNMT1 and C/EBPα in the Regulation of CYP11A1 Expression During Syncytialization of Human Placental Trophoblasts.

CEBPA DNMT1

1.34e-05374238146648
Pubmed

Retinoblastoma protein promotes uterine epithelial cell cycle arrest and necroptosis for embryo invasion.

RB1 PGR

1.34e-05374233399260
Pubmed

DNA methyltransferase Dnmt1 associates with histone deacetylase activity.

RB1 DNMT1

1.34e-05374210615135
Pubmed

Systematic mapping of genetic interactions for de novo fatty acid synthesis identifies C12orf49 as a regulator of lipid metabolism.

DDX59 KMT5B SCG3 RPUSD3 E2F7 CKAP2L UNC13D PPHLN1 SLC26A6 SOWAHB PADI3 CAPN15

2.23e-051327741232694731
Pubmed

Retinoblastoma protein positively regulates terminal adipocyte differentiation through direct interaction with C/EBPs.

CEBPA RB1

2.67e-0547428946919
Pubmed

Methyl-CpG-binding protein, MeCP2, is a target molecule for maintenance DNA methyltransferase, Dnmt1.

RB1 DNMT1

2.67e-05474212473678
Pubmed

Concomitant inactivation of Rb and E2f8 in hematopoietic stem cells synergizes to induce severe anemia.

RB1 E2F7

2.67e-05474222422820
Pubmed

Transcription of mouse DNA methyltransferase 1 (Dnmt1) is regulated by both E2F-Rb-HDAC-dependent and -independent pathways.

RB1 DNMT1

2.67e-05474212799438
Pubmed

DNMT1 forms a complex with Rb, E2F1 and HDAC1 and represses transcription from E2F-responsive promoters.

RB1 DNMT1

2.67e-05474210888886
Pubmed

CCAAT/enhancer-binding protein alpha (C/EBPalpha) and hepatocyte nuclear factor 4alpha (HNF4alpha) synergistically cooperate with constitutive androstane receptor to transactivate the human cytochrome P450 2B6 (CYP2B6) gene: application to the development of a metabolically competent human hepatic cell model.

CYP2B6 CEBPA

2.67e-05474220622021
Pubmed

MYCN is recruited to the RASSF1A promoter but is not critical for DNA hypermethylation in neuroblastoma.

RB1 DNMT1

2.67e-05474223280764
Pubmed

PR-SET7 and SUV4-20H regulate H4 lysine-20 methylation at imprinting control regions in the mouse.

KMT5B KMT5C

2.67e-05474218724273
Pubmed

STAT3 promotes melanoma metastasis by CEBP-induced repression of the MITF pathway.

CEBPA MITF

2.67e-05474233323974
Pubmed

HDLBP Promotes Hepatocellular Carcinoma Proliferation and Sorafenib Resistance by Suppressing Trim71-dependent RAF1 Degradation.

DLG5 UBAP2 CEBPA VWA8 RPUSD3 CKAP2L ZNF207 PPHLN1 ROS1 FLRT3 XRCC6 DNMT1

3.07e-051371741236244648
Pubmed

Proteome-scale mapping of binding sites in the unstructured regions of the human proteome.

NCOR1 UBAP2 AP5B1 MITF TEX14 POM121C TP53BP2

3.71e-0543074735044719
Pubmed

Binding of Ku and c-Abl at the kinase homology region of DNA-dependent protein kinase catalytic subunit.

RB1 XRCC6

4.45e-0557429312071
Pubmed

Mitf cooperates with Rb1 and activates p21Cip1 expression to regulate cell cycle progression.

RB1 MITF

4.45e-05574215716956
Pubmed

Association of the Ku autoantigen/DNA-dependent protein kinase holoenzyme and poly(ADP-ribose) polymerase with the DNA binding domain of progesterone receptors.

XRCC6 PGR

4.45e-05574210750018
Pubmed

Dnmt1-dependent Chk1 pathway suppression is protective against neuron division.

RB1 DNMT1

4.45e-05574228928282
Pubmed

In prostate cancer cells the interaction of C/EBPalpha with Ku70, Ku80, and poly(ADP-ribose) polymerase-1 increases sensitivity to DNA damage.

CEBPA XRCC6

4.45e-05574216490787
Pubmed

The DNA methyltransferases associate with HP1 and the SUV39H1 histone methyltransferase.

RB1 DNMT1

4.45e-05574212711675
Pubmed

Prohibitin co-localizes with Rb in the nucleus and recruits N-CoR and HDAC1 for transcriptional repression.

NCOR1 RB1

4.45e-05574212466959
Pubmed

Myristoylated alanine-rich C-kinase substrate effector domain phosphorylation regulates the growth and radiation sensitization of glioblastoma.

TEP1 CNOT3 XRCC6

5.76e-053574330942445
Pubmed

A silencing pathway to induce H3-K9 and H4-K20 trimethylation at constitutive heterochromatin.

KMT5B KMT5C

6.66e-05674215145825
Pubmed

A chromatin-wide transition to H4K20 monomethylation impairs genome integrity and programmed DNA rearrangements in the mouse.

KMT5B KMT5C

6.66e-05674218676810
Pubmed

Negative regulation of CD8 expression via Cd8 enhancer-mediated recruitment of the zinc finger protein MAZR.

NCOR1 DNMT1

6.66e-05674216491076
Pubmed

Aging reduces proliferative capacities of liver by switching pathways of C/EBPalpha growth arrest.

CEBPA RB1

6.66e-05674212757710
Pubmed

ATM mediates pRB function to control DNMT1 protein stability and DNA methylation.

RB1 DNMT1

6.66e-05674223754744
Pubmed

Proliferating cell nuclear antigen interacts with the CRL4 ubiquitin ligase subunit CDT2 in DNA synthesis-induced degradation of CDT1.

CDT1 DNMT1

6.66e-05674230301766
Pubmed

Gankyrin Promotes Tumor-Suppressor Protein Degradation to Drive Hepatocyte Proliferation.

CEBPA RB1

9.31e-05774230109252
Pubmed

Antagonistic regulation by the transcription factors C/EBPα and MITF specifies basophil and mast cell fates.

CEBPA MITF

9.31e-05774223871207
Pubmed

Liver tumors escape negative control of proliferation via PI3K/Akt-mediated block of C/EBP alpha growth inhibitory activity.

CEBPA RB1

1.24e-04874215107404
Pubmed

An improved smaller biotin ligase for BioID proximity labeling.

FSIP2 NCOR1 LRP12 POM121C

1.42e-0412374426912792
Pubmed

A Damage-Independent Role for 53BP1 that Impacts Break Order and Igh Architecture during Class Switch Recombination.

KMT5B KMT5C

1.99e-041074227320916
Pubmed

Histone H4K20me3 and HP1α are late heterochromatin markers in development, but present in undifferentiated embryonic stem cells.

KMT5B KMT5C

1.99e-041074221576353
Pubmed

Rb is critical in a mammalian tissue stem cell population.

RB1 E2F7

1.99e-041074217210791
Pubmed

Mapping the MOB proteins' proximity network reveals a unique interaction between human MOB3C and the RNase P complex.

MRPS7 DLG5 COL8A1 PPHLN1 XRCC6 DNMT1

2.11e-0439974637536630
Pubmed

The proto-oncoprotein FBI-1 interacts with MBD3 to recruit the Mi-2/NuRD-HDAC complex and BCoR and to silence p21WAF/CDKN1A by DNA methylation.

NCOR1 DNMT1

2.43e-041174223658227
Pubmed

The transcriptional repressor Blimp1/PRDM1 regulates the maternal decidual response in mice.

CD74 PGR

3.43e-041374232493987
Pubmed

Enzymatic nucleosome acetylation selectively affects activity of histone methyltransferases in vitro.

KMT5B KMT5C

4.61e-041574235907431
Pubmed

Phosphorylation of thyroid hormone receptor-associated nuclear receptor corepressor holocomplex by the DNA-dependent protein kinase enhances its histone deacetylase activity.

NCOR1 XRCC6

4.61e-041574217242407
Pubmed

Polymorphism in the IL18 gene and epithelial ovarian cancer in non-Hispanic white women.

NCOR1 XRCC6 PGR DNMT1

4.86e-0417074419064572
Pubmed

C/EBPalpha regulates formation of S-phase-specific E2F-p107 complexes in livers of newborn mice.

CEBPA RB1

5.26e-041674210082561
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

NCOR1 VWA8 KMT5C LRP3 TEP1 POM121C ZBTB42 DHX34 SOWAHB

5.54e-04110574935748872
Pubmed

A protein interaction network links GIT1, an enhancer of huntingtin aggregation, to Huntington's disease.

PTPRK PPHLN1 XRCC6

5.59e-047574315383276
Pubmed

Cdkn1c Boosts the Development of Brown Adipose Tissue in a Murine Model of Silver Russell Syndrome.

CEBPA RB1

5.95e-041774226963625
Pubmed

Intrahepatic bile ducts develop according to a new mode of tubulogenesis regulated by the transcription factor SOX9.

HHEX CEBPA

6.68e-041874219403103
Pubmed

Genetic mapping of five mouse genes encoding synaptotagmins.

SYT3 CD74

7.46e-04197428747928
Pubmed

Molecular Profiling Reveals Involvement of ESCO2 in Intermediate Progenitor Cell Maintenance in the Developing Mouse Cortex.

PLPPR4 CKAP2L CDT1

8.62e-048774333798452
Pubmed

Human transcription factor protein interaction networks.

MRPS7 IRF9 NCOR1 UBAP2 RB1 MITF MSANTD2 POM121C CNOT3 XRCC6

8.73e-041429741035140242
Pubmed

Genome-wide association study of ancestry-specific TB risk in the South African Coloured population.

VWA8 E2F7

9.14e-042174224057671
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

DLG5 UBAP2 PLPPR4 VWA8 FLRT3 DHX34

9.30e-0452974614621295
Pubmed

Developmental diversification of cortical inhibitory interneurons.

SOX21 E2F7 DNMT1

9.82e-049174329513653
Pubmed

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

NCOR1 UBAP2 PLPPR4 SYT3 MSANTD2 XRCC6 TP53BP2 DNMT1

1.01e-0396374828671696
Pubmed

The high-mobility-group domain of Sox proteins interacts with DNA-binding domains of many transcription factors.

HHEX CEBPA

1.20e-032474216582099
Pubmed

Expansion of hematopoietic stem cell phenotype and activity in Trp53-null mice.

RB1 DNMT1

1.30e-032574212829028
Pubmed

Hepatic Notch2 deficiency leads to bile duct agenesis perinatally and secondary bile duct formation after weaning.

HHEX CEBPA

1.40e-032674225446530
Pubmed

Interactome of the negative regulator of nuclear import BRCA1-binding protein 2.

EFHC1 DNMT1

1.40e-032674225820252
Pubmed

Human origin recognition complex large subunit is degraded by ubiquitin-mediated proteolysis after initiation of DNA replication.

RB1 CDT1

1.40e-032674211931757
Pubmed

The Interleukin-2-mTORc1 Kinase Axis Defines the Signaling, Differentiation, and Metabolism of T Helper 1 and Follicular B Helper T Cells.

E2F7 TNS2 CD74 CDT1

1.42e-0322774426410627
Pubmed

Brg1 coordinates multiple processes during retinogenesis and is a tumor suppressor in retinoblastoma.

RB1 MITF

1.51e-032774226628093
Pubmed

BMP receptor 1b is required for axon guidance and cell survival in the developing retina.

CEBPA EFNB2

1.51e-032774212654290
Pubmed

The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts.

MRPS7 RPUSD3 RAVER2 ZNF207 PPHLN1 DHX34 XRCC6

1.65e-0380774722681889
Pubmed

Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst.

NCOR1 HHEX CEBPA SOX21 ZNF207 XRCC6 DNMT1

1.66e-0380874720412781
Pubmed

Proteomic identification of the MYST domain histone acetyltransferase TIP60 (HTATIP) as a co-activator of the myeloid transcription factor C/EBPalpha.

CEBPA RB1

1.75e-032974218239623
Pubmed

The phosphorylation status of T522 modulates tissue-specific functions of SIRT1 in energy metabolism in mice.

NCOR1 CEBPA

1.75e-032974228364022
Pubmed

A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration.

NCOR1 COL8A1 TNS2 TEP1 TP53BP2 HSPA13

1.89e-0360874616713569
Pubmed

USP7 Regulates Cytokinesis through FBXO38 and KIF20B.

CDT1 POM121C DNMT1

1.97e-0311674330804394
Pubmed

A proteomics approach to identify proliferating cell nuclear antigen (PCNA)-binding proteins in human cell lysates. Identification of the human CHL12/RFCs2-5 complex as a novel PCNA-binding protein.

XRCC6 DNMT1

2.00e-033174212171929
Pubmed

Common genetic variation in candidate genes and susceptibility to subtypes of breast cancer.

RB1 PGR DNMT1

2.02e-0311774319124506
Pubmed

HMGB1 interacts with many apparently unrelated proteins by recognizing short amino acid sequences.

RB1 DNMT1

2.13e-033274211748221
InteractionGRAMD1A interactions

TCTN3 CALR3 PTPRO LRP3 CD74 ROS1 HSPA13

2.53e-06168737int:GRAMD1A
GeneFamilyLow density lipoprotein receptors

LRP12 LRP3

7.98e-0413592634
GeneFamilyFibronectin type III domain containing

PTPRK PTPRO ROS1 FLRT3

1.84e-03160594555
GeneFamilyProtein tyrosine phosphatases, receptor type

PTPRK PTPRO

2.11e-0321592813
ToppCellCOPD-Epithelial-ATII|COPD / Disease state, Lineage and Cell class

COL8A1 EFNB2 PTPRK ROS1 PLA2G4F FLRT3

7.19e-07188746eb6d79d733b53f64ca615bb777c64ed456866549
ToppCellParenchymal-10x3prime_v2-Epithelial-Epi_alveolar-Dividing_AT2|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

CYP2B6 AP5B1 CDT1 PLA2G4F FLRT3 TEP1

1.03e-06200746befc25cbcbac2c02e5fd33d6e78e59979050090c
ToppCelldroplet-Lung-nan-3m-Myeloid-Myeloid_Dendritic_Type_1|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CEBPA PLPPR4 PTPRO CD74 TEP1

7.50e-061627458a488ecd25ef41468c3c7766eb936dbc2f7665a9
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-3m-Epithelial-neuronal_stem_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SOX21 PTPRO LRP3 CDT1 NSUN7

8.20e-061657451703d3eb644b3c743ad3c5532b1d29ea010c79c8
ToppCelldroplet-Lung-3m-Hematologic-myeloid-myeloid_dendritic_cell-myeloid_dendritic_type_1|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CEBPA PLPPR4 PTPRO CD74 TEP1

9.47e-06170745138235227fc4c3d660c3a06e8e5167bf64f076b3
ToppCelldroplet-Lung-3m-Hematologic-myeloid-myeloid_dendritic_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CEBPA PLPPR4 PTPRO CD74 TEP1

1.03e-05173745f66aebceb3eb389bc5ff6c0b398d6f4e9959a14f
ToppCelldroplet-Limb_Muscle-nan-24m-Endothelial-unknown|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HHEX RPUSD3 HYLS1 UNC13D ZBTB42

1.18e-05178745f2002a5c4758d0af6c1880ca12f0af0d5e8888e4
ToppCell5'-Airway_Nasal-Immune_Myeloid-Myeloid_macrophage-lung_macrophage|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

IRF9 RB1 TMEM86B CD74 ZBTB42

1.32e-051827454a85429d365c4b2d73fc921f261b4b7635ac40bd
ToppCell5'-Airway_Nasal-Immune_Myeloid-Myeloid_macrophage-lung_macrophage-Interstitial_macrophage_perivascular|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

IRF9 RB1 TMEM86B CD74 ZBTB42

1.32e-0518274553213af34af3337f5edc734d3b7b79e4349eac0d
ToppCell5'-Airway_Nasal-Immune_Myeloid-Myeloid_macrophage-lung_macrophage-Interstitial_macrophage_perivascular-Interstitial_macrophage_perivascular_L.1.2.1.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

IRF9 RB1 TMEM86B CD74 ZBTB42

1.32e-051827457909089ed6325c44edd6f9b7e8b1d542398222ea
ToppCellCOPD-Epithelial-ATII|World / Disease state, Lineage and Cell class

COL8A1 EFNB2 PTPRK ROS1 PLA2G4F

1.35e-051837458e9aab4eeec2e282c2cab9bfca6dbf40d660c7b9
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-24m-Epithelial-Bergmann_glial_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DLG5 SOX21 GPR153 SCG3 RAVER2

1.39e-05184745f6148e9591e8845cc62668e49fd52755257cdc7e
ToppCellIPF-Epithelial-ATII|IPF / Disease state, Lineage and Cell class

COL8A1 PTPRK ROS1 PLA2G4F FLRT3

1.43e-05185745563b4e6d92bb5d77a3829556116a8e99aebac615
ToppCellControl-Epithelial-ATII|World / Disease state, Lineage and Cell class

COL8A1 PTPRK ROS1 PLA2G4F FLRT3

1.46e-05186745f4b6e401e19a71beddc73d8a1e08359f7c4025cf
ToppCellControl-Epithelial-ATII|Control / Disease state, Lineage and Cell class

COL8A1 PTPRK ROS1 PLA2G4F FLRT3

1.62e-05190745d50902a3abcc18aafa36d83cc2c6e07d7f7cb197
ToppCellControl-Multiplet-Multiplet|World / Disease state, Lineage and Cell class

COL8A1 PTPRK ROS1 PLA2G4F FLRT3

1.70e-051927451bfd022d5b87cf8a5d5069f559339a553a52a0a2
ToppCelldroplet-Lung-1m-Hematologic-myeloid-alveolar_macrophage-proliferating_alveolar_macrophage|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

LRP12 E2F7 CKAP2L CDT1 DNMT1

1.84e-05195745c1435e61e4f0cf457f26ae436936048932ceb0db
ToppCellTracheal-10x5prime-Stromal-Fibroblastic-Fibro_peribronchial|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

COL8A1 PLPPR4 GPR153 ITIH5 PGR

2.07e-052007458ab0051544ea32eb8b3f7f8ba7582deaf8bf26c0
ToppCellcritical-Epithelial-FOXN4+|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

RB1 E2F7 HYLS1 CDT1 DNMT1

2.07e-05200745f39db4250ce220a3eb58edee3f7fc3671701d46f
ToppCellE18.5-samps-Mesenchymal-Myofibroblast-myofibroblast_-_mature_-_B|E18.5-samps / Age Group, Lineage, Cell class and subclass

FLRT3 PADI3 PGR DNAH1

8.02e-05137744b553958e7e6dcd887d860e34d3983cbb85cefaa6
ToppCellPBMC-Severe-Lymphocyte-B-B_cell-B_naive-B_naive-9|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

HHEX SOX21 CD74 NSUN7

1.14e-04150744d9931507257c64ead4a53786e6822f51962c6015
ToppCelldroplet-Fat-SCAT-30m-Myeloid|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PTPRO CD74 TEX14 TEP1

1.26e-0415474473de626b210ec5482ba89a65e784c1e77ff2894e
ToppCelldroplet-Fat-SCAT-30m-Myeloid-myeloid_cell|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PTPRO CD74 TEX14 TEP1

1.26e-0415474456fe9953e58f71626d3ddf63d340ed35dfc4ce9f
ToppCellPND07-Immune-Immune_Myeloid-DC-cDC2-cDC2_prolif|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

LRP12 CD74 CDT1 TEP1

1.29e-04155744b5d5c38b269e9318970fcce564df1c8ed7a7ccc6
ToppCell368C-Endothelial_cells-Endothelial-E|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)

FSIP2 PTPRK RAVER2 E2F7

1.32e-041567444877aabf647238c0279e497345b6a6d5ee07ef9c
ToppCell368C-Endothelial_cells-Endothelial-E-|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)

FSIP2 PTPRK RAVER2 E2F7

1.32e-041567441d681fa17e62815f5d5f90c86be3c248b38e011b
ToppCellprimary_visual_cortex-Neuronal-glutamatergic_neuron-L5_IT-L5_IT_VISp_Hsd11b1_Endou|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

COL8A1 PTPRK RAVER2 CD74

1.39e-04158744c8af8964a140acb2987e3b4906d72c546108d229
ToppCellPBMC-Mild-Lymphocyte-B-B_cell-B_naive-B_naive-13|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

HHEX PTPRK HYLS1 CD74

1.53e-0416274428b3a6ae5519a267eefb70436d3190a387d027b9
ToppCellE16.5-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT2-AT2_mature|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CEBPA ROS1 NSUN7 PADI3

1.53e-041627448e0f03fcc25b2ea777e8478fbf771699cf93719c
ToppCellE16.5-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT2|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CEBPA ROS1 NSUN7 PADI3

1.53e-04162744e0417f1242edf71934fe62bccc55c4678f7ff4ac
ToppCellE18.5-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT2-AT2_prolif|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CALR3 CEBPA AP5B1 ROS1

1.57e-04163744d2fcd6f561748f7d29a051c504f016952ba32d0f
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c12-MKI67-TYROBP|Severe-critical_progression_d12-22 / Compartment, severity and other cell annotations on 10x 3' data (130k)

KMT5C E2F7 CKAP2L HYLS1

1.61e-041647444ef776d1bab4103d42d3a4f22cdfb49e8d2bc5a0
ToppCellkidney_cells-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Glomerular_Capillary_Endothelial_Cell_prolif|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

IRF9 EFNB2 E2F7 CDT1

1.61e-041647441592a5becad7e0f3f990f0d7581d75fcfc7da023
ToppCellfacs-Heart-LV-24m-Myeloid|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PTPRO CD74 PADI3 PGR

1.64e-0416574441707e66542ea27133043740ef9e58ab89b06607
ToppCellfacs-Lung-nan-3m-Myeloid-myeloid_dendritic_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DDX59 CEBPA VWA8 UNC13D

1.68e-041667445c132f505dc5f699c87913f140344fc9f8e7e0f5
ToppCellwk_08-11-Mesenchymal-Fibroblast-Alveolar_fibro|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

IRF9 PLPPR4 PCDH11X ITIH5

1.68e-0416674465dafed953b01a9830b54309af75c7a561e88336
ToppCelldroplet-Lung-LUNG-1m-Myeloid-myeloid_dendritic_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CEBPA PLPPR4 CD74 TEP1

1.68e-04166744c215c4aede38d355d35fd26cd7ef2c19efecd0e6
ToppCelldroplet-Lung-21m-Hematologic-myeloid-myeloid_dendritic_cell-myeloid_dendritic_type_1|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CEBPA PTPRO CD74 TEP1

1.72e-041677449526e2c7673d569d04e0728a2526318e67432e0a
ToppCelldroplet-Heart-HEART_(ALL_MINUS_AORTA)-30m-Hematologic-fibroblast|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SYT3 MITF REPS2 TEP1

1.72e-04167744f5bffa77061baec0ba87bd688a047595f32534db
ToppCellfacs-Lung-3m-Hematologic-myeloid-myeloid_dendritic_cell-myeloid_dendritic_type_1|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

PLPPR4 PTPRO CD74 TEP1

1.72e-04167744fd84a99ea142d1684cdcf4a88ef1d541760bc78a
ToppCellfacs-Trachea-24m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l44-58|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

TMLHE REPS2 SOWAHB NSUN7

1.80e-04169744d382a76d85875663502cc7dde2e3e0682605768e
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_G2M|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

E2F7 CKAP2L SOWAHB DNMT1

1.80e-04169744b253a4a50c06d36228fcd5d856c57202cbac158f
ToppCelldroplet-Lung-LUNG-1m-Myeloid-Myeloid_Dendritic_Type_1|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CEBPA PLPPR4 CD74 TEP1

1.80e-04169744735655e75511c5c41aca667909e8bb52a0ad7fc6
ToppCelldroplet-Lung-nan-21m-Myeloid-Myeloid_Dendritic_Type_1|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CEBPA PLPPR4 CD74 TEP1

1.84e-04170744d72eb77271d61e27a3d247149561c7f45fadb28b
ToppCellfacs-Marrow-Granulocytes-3m-Myeloid-macrophage|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CEBPA PTPRO AP5B1 TEP1

1.93e-041727447fb31ccbcd0204c3612986a6bc20d57ed6825e9c
ToppCellP15-Mesenchymal-developing_mesenchymal_cell-mesenchymal_proliferating_cell|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

E2F7 CKAP2L CDT1 DNMT1

1.93e-041727447c238a7375341d4647ba7274d93fddfb6fae7ce4
ToppCellfacs-Marrow-Granulocytes-3m-Myeloid-CD4+_macrophage|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CEBPA PTPRO AP5B1 TEP1

1.93e-041727442a4614b3d25e8c6b095e6992d8ca35371dcdb5e1
ToppCell10x5'-bone_marrow-Lymphocytic_NK-Cycling_NK|bone_marrow / Manually curated celltypes from each tissue

E2F7 CKAP2L CDT1 DNMT1

1.97e-041737448a9dd85f718564c07cf3120ad648daeb60c94fc5
ToppCellPND07-Immune-Immune_Myeloid-DC-cDC1-cDC1_prolif|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

E2F7 HYLS1 CD74 DNMT1

1.97e-0417374428c98a9a54aa2cfa67464db4f628c9357ad185b9
ToppCell10x5'-Lung-Lymphocytic_NK-Cycling_NK|Lung / Manually curated celltypes from each tissue

CYP2B6 E2F7 CKAP2L CDT1

1.97e-04173744d815832f89f70662706620e3b03ebb1dabec0034
ToppCelldroplet-Kidney-KIDNEY-30m-Epithelial-Epcam____podocyte-3|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EFNB2 PCDH11X ROS1 DNAH1

2.01e-0417474476310c0af1d7df6a4de3816838b2ac2892f68746
ToppCellPND03-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Deuterosomal|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

EFHC1 PLPPR4 CKAP2L HYLS1

2.01e-04174744179a52d77899a929396b98d4ab2c270dd2ec708e
ToppCell3'-Distal_airway-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell-Deuterosomal-Deuterosomal_L.0.3.4.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

E2F7 CKAP2L HYLS1 CDT1

2.01e-041747440227fea1678baa9168bd47c3b4aacb2592bb5867
ToppCell3'-Distal_airway-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

E2F7 CKAP2L HYLS1 CDT1

2.01e-04174744c2f8c59fca5f1ff6ffa6dc8cfce62da4b19fe9b3
ToppCellfacs-Trachea-24m-Hematologic-myeloid-tracheal_macrophage-macrophage_of_tracheal_l15|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

HHEX PTPRO CD74 FLRT3

2.01e-04174744c52aed2ffe9c648e5f23e3459e2d331d6ca214e3
ToppCellPND07-Endothelial-Endothelial_blood-vessel-Microvascular_EC-EPC-EPC_prolif|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

E2F7 CKAP2L CDT1 DNMT1

2.01e-0417474466555c610251ea04f968c258e312d720c18e7cde
ToppCell3'-Distal_airway-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell-Deuterosomal|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

E2F7 CKAP2L HYLS1 CDT1

2.01e-0417474484024c04b0ce9f7068677d2d99ede56882b7dbd2
ToppCellPND03-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Deuterosomal-Deuterosomal_mature|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

EFHC1 PLPPR4 CKAP2L HYLS1

2.01e-041747449165a1094d345328e58962f4b2a20334c3e93ead
ToppCellfacs-Limb_Muscle-Muscle_Diaphragm-18m-Lymphocytic-nan|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HHEX UNC13D CDT1 DNMT1

2.06e-04175744db6be3e9e339918418fcaf9001ea15207aa6c993
ToppCellfacs-Limb_Muscle-Muscle_Diaphragm-18m-Lymphocytic|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HHEX UNC13D CDT1 DNMT1

2.06e-041757448acac10c9eedccebcf3a3fe31bfee35afa54579f
ToppCelldroplet-Heart-HEART-1m-Hematologic|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CEBPA PLPPR4 PTPRO TEP1

2.06e-0417574443b9cfd7c47d57244565c641e57f3256b5900804
ToppCelldroplet-Heart-HEART-1m-Hematologic-leukocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CEBPA PLPPR4 PTPRO TEP1

2.06e-04175744a2fed97cf8d28f9936fe791e5e8c43d2430330c9
ToppCellNS-critical-d_16-33-Epithelial-FOXN4+|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

E2F7 HYLS1 CDT1 PGR

2.10e-041767447cf1a06ceee1ec06532f44c729c31b4d58e5ea49
ToppCelldroplet-Heart-HEART-1m-Hematologic-leukocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CEBPA PLPPR4 PTPRO TEP1

2.10e-041767441df640f88667e2dad30e65279d6d33bba75024c1
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

COL8A1 SH3RF3 PGR DNAH1

2.10e-04176744b4a23d8d1414434adeb237a96f28c825f1aebd77
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

COL8A1 SH3RF3 PGR DNAH1

2.10e-0417674466c9c6b59030f67e8d746a9c6930e50923f2ded1
ToppCell5'-Adult-Appendix-Endothelial-lymphatic_endothelial-LEC5_(CLDN11+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TCTN3 DDX59 SCG3 ZBTB42

2.15e-041777443a85aa2bf3f2fdbea57d22d68e022cb3f6c2eb65
ToppCellTCGA-Skin-Metastatic-Melanoma-Skin_Cutaneous_Melanoma-5|TCGA-Skin / Sample_Type by Project: Shred V9

COL8A1 EFNB2 FLRT3 ITIH5

2.20e-04178744ad5cd505ca1cef8ac29b2af7e2c3e01ebc140c14
ToppCellfacs-Limb_Muscle-Muscle_Diaphragm-18m-Lymphocytic-T_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HHEX UNC13D CDT1 DNMT1

2.20e-041787445ac5257d88fa0dc67714881d6f005f6cea925710
ToppCellDividing_Macrophages-Donor_05|World / lung cells shred on cell class, cell subclass, sample id

E2F7 CKAP2L CDT1 TEX14

2.20e-041787446557688c6790a5bcc3b9aea5b8789cf9506b3c54
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

CYP2B6 NPTX1 PTPRK REPS2

2.20e-04178744f5ed4a6e3eb8056b1be1fb311021710c95bdf888
ToppCellPND28-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1-AT1_mature|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

FLRT3 REPS2 SH3RF3 TP53BP2

2.20e-04178744a3af5d9c55858e36be0498081029ecb0acaeb3d3
ToppCellPND28-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

FLRT3 REPS2 SH3RF3 TP53BP2

2.20e-04178744b3b88989bd602cfb55bb5c47731deb99288a8952
ToppCelldroplet-Heart-4Chambers-21m-Mesenchymal-nan|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

AP5B1 PCDH11X SH3RF3 DNAH1

2.24e-04179744b44e2d53b82c3c141bfc6539054b19708200a0d9
ToppCellfacs-Pancreas-Exocrine-18m-Mesenchymal|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL8A1 GPR153 SH3RF3 ITIH5

2.34e-04181744269b39ac65790061d54eab47a8eeb024403f0348
ToppCellfacs-Pancreas-Exocrine-18m-Mesenchymal-pancreatic_stellate_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL8A1 GPR153 SH3RF3 ITIH5

2.34e-04181744cd4f744b6b64ba6c22ec07afd1d3058a2546909d
ToppCellfacs-Pancreas-Exocrine-18m-Mesenchymal-pancreatic_stellate_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL8A1 GPR153 SH3RF3 ITIH5

2.34e-04181744c8395ae872aa80b3ae1ab7c53e57b3ca15aeb0e2
ToppCellremission-B_naive|World / disease stage, cell group and cell class

HHEX PTPRK CD74 NSUN7

2.39e-04182744cc1dfd2de35aee1a26f7efd78e108b60a3556ec5
ToppCelldroplet-Marrow-nan-3m-Myeloid-promonocyte|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CEBPA PTPRO TEP1 DNMT1

2.39e-04182744bc8d621be57f76d718d9b0f11e023b0f4dcb668d
ToppCellPCW_05-06-Epithelial-Epithelial_neuroendo-epi_neuroendocrine2[NE2]_(12)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

NPTX1 SOX21 SCG3 PLA2G4F

2.39e-04182744dc29e8735c3562ce32322351d28f7d9709208ebf
ToppCellCOVID-19-lung-AT1|COVID-19 / Disease (COVID-19 only), tissue and cell type

COL8A1 UNC13D FLRT3 REPS2

2.44e-041837447b1a385ed54f93bfe85bf0c162e42d05d516b45c
ToppCellremission-B_naive|remission / disease stage, cell group and cell class

HHEX PTPRK CD74 NSUN7

2.44e-04183744280d55d67f1d44594206da2f3a332c9d799dbdf0
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PCDH11X MYH15 ROS1 DNAH1

2.49e-041847442cbed6462fea2622871bb7e49b0df3d984239281
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-24m-Epithelial-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DLG5 SOX21 GPR153 SCG3

2.49e-041847446b0c110d8930df99043c3b99cf4d873985126960
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-24m-Epithelial|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DLG5 SOX21 GPR153 SCG3

2.49e-0418474435928fc5f7bbf8c7b09181a2bd27e22dff42ec16
ToppCellP03-Epithelial-epithelial_progenitor_cell-epithelial_unknown_3|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

COL8A1 SOX21 PLPPR4 ITIH5

2.49e-041847448880ff36c243cc60a524d74934d000aef26a70ac
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PCDH11X MYH15 ROS1 DNAH1

2.49e-04184744ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PCDH11X MYH15 ROS1 DNAH1

2.49e-041847442b19a8c5f823e00812908b23e66bb4e563278aff
ToppCellIPF-Epithelial-ATII|World / Disease state, Lineage and Cell class

COL8A1 PTPRK ROS1 PLA2G4F

2.60e-041867446a4ff2da0af0f5e590d9f9daa5b5e9ac8c868947
ToppCellPBMC-Convalescent-Lymphocyte-B-B_cell-B_naive|Convalescent / Location, Disease Group, Cell group, Cell class (2021.03.09)

HHEX PTPRK CD74 NSUN7

2.60e-04186744f352c63666273defea3e57ba3a3bfad52c4ea65b
ToppCellfacs-Marrow-T-cells-3m-Lymphocytic-late_pro-B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PCDH11X E2F7 CKAP2L HYLS1

2.60e-041867443993f1ef8a33b8a75dfd3db8d4845b5afbb0bb3d
ToppCellPBMC-Convalescent-Lymphocyte-B-B_cell-B_naive-|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

HHEX PTPRK CD74 NSUN7

2.60e-04186744e2d265003aaea1acaf618d3f102c9933c19102e6
ToppCellfacs-Marrow-T-cells-3m-Lymphocytic-late_pro_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PCDH11X E2F7 CKAP2L HYLS1

2.60e-04186744ec6d0c29e196e374baa96dd3d506f489c959e77e
ToppCellControl-Epithelial-Club|World / Disease state, Lineage and Cell class

CYP2B6 PTPRK ROS1 FLRT3

2.60e-041867449798428691408e17ff2af2fe2d1b345f074d67e4
ToppCellCOVID-19_Convalescent-Lymphoid_B-B_naive|COVID-19_Convalescent / Disease group, lineage and cell class

HHEX PTPRK CD74 NSUN7

2.60e-041867449d339f57036d17572882ebb801f2be9b1d1ddc1c
ToppCellPBMC-Convalescent-Lymphocyte-B-B_cell-B_naive|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

HHEX PTPRK CD74 NSUN7

2.65e-04187744e7970ec1507adfa91a296489166142cb9400421f
ToppCellIPF-Epithelial-ATII|Epithelial / Disease state, Lineage and Cell class

COL8A1 ROS1 PLA2G4F TEX14

2.70e-041887445f5fad2773e421760e67dbace23fd1f847a2e1e0
ToppCellnormal-na-Lymphocytic_B-B_naive-male|normal / PBMC cell types (v2) per disease, treatment status, and sex

HHEX RB1 CD74 NSUN7

2.70e-04188744ec72ba73b10c6f2ff39699b6b46b90a3e95a4c24
ToppCellIPF-Epithelial-Club|IPF / Disease state, Lineage and Cell class

CYP2B6 PTPRK ROS1 FLRT3

2.76e-04189744f3fcef008ef252b29ac6d567fef27f9acf9cd70f
ToppCell3'-GW_trimst-1-LargeIntestine-Endothelial-blood_vessel_EC-Mature_arterial_EC|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

HHEX COL8A1 EFNB2 PCDH11X

2.81e-0419074492fdfed12061ee9f6c7171cf8a7f3344921f2d40
Drugrac Geosmin-d3

CYP2B6 NPTX1 SOCS5

2.62e-069733CID000001213
Drug0297417-0002B [362658-29-5]; Down 200; 10uM; MCF7; HT_HG-U133A

CEBPA VWA8 LRP3 TNS2 CDT1 DHX34 ZNF692

2.67e-061917376900_DN
Drug5213008; Down 200; 18uM; MCF7; HT_HG-U133A_EA

IRF9 CEBPA VWA8 GPR153 SOCS5 TNS2 DHX34

3.07e-06195737898_DN
DiseaseMalignant neoplasm of breast

MRPS7 NCOR1 HHEX DDX59 SYT3 RB1 CD74 PPHLN1 REPS2 PADI3 TP53BP2 PGR DNMT1

1.77e-0610747213C0006142
DiseaseMammary Carcinoma, Human

MRPS7 NCOR1 HHEX RB1 CD74 REPS2 TP53BP2 PGR DNMT1

5.25e-06525729C4704874
DiseaseMammary Neoplasms, Human

MRPS7 NCOR1 HHEX RB1 CD74 REPS2 TP53BP2 PGR DNMT1

5.25e-06525729C1257931
DiseaseMammary Neoplasms

MRPS7 NCOR1 HHEX RB1 CD74 REPS2 TP53BP2 PGR DNMT1

5.42e-06527729C1458155
DiseaseBreast Carcinoma

MRPS7 NCOR1 HHEX RB1 CD74 REPS2 TP53BP2 PGR DNMT1

6.39e-06538729C0678222
DiseasePolydactyly

TCTN3 DDX59 CKAP2L HYLS1

1.96e-04117724C0152427
Diseaseocular hypertension, response to triamcinolone acetonide

VWA8 RPUSD3 TEX14

2.37e-0449723EFO_0006954, EFO_1001069
Diseaseatopic eczema, childhood onset asthma, atopic march

EFHC1 AP5B1

3.18e-0411722EFO_0000274, EFO_0007755, MONDO_0005405
Diseaserespiratory system disease

HHEX CEBPA PTPRK AP5B1

4.44e-04145724EFO_0000684
DiseaseNon-Small Cell Lung Carcinoma

RB1 E2F7 CD74 ROS1

5.85e-04156724C0007131
Diseasedistal arthrogryposis (implicated_via_orthology)

MYH15 ZBTB42

6.04e-0415722DOID:0050646 (implicated_via_orthology)
Diseaseelectroencephalogram measurement

PTPRK MITF E2F7

7.98e-0474723EFO_0004357
Diseaseemphysema pattern measurement

VWA8 SOWAHB

9.77e-0419722EFO_0005850
Diseasepolycystic ovary syndrome (biomarker_via_orthology)

NCOR1 PGR

1.20e-0321722DOID:11612 (biomarker_via_orthology)
Diseaseage of onset of childhood onset asthma

HHEX CEBPA AP5B1

1.50e-0392723OBA_2001015
DiseaseLiver carcinoma

CYP2B6 CEBPA RB1 CKAP2L CDT1 SLC26A6

1.50e-03507726C2239176
Diseaseasthma

CEBPA PTPRK AP5B1 SCG3 E2F7 UNC13D XRCC6

2.36e-03751727MONDO_0004979

Protein segments in the cluster

PeptideGeneStartEntry
GVGKIPPTYQIRFLP

CYP2B6

476

P20813
LQKPPYQDGLKPEGI

CALR3

256

Q96L12
VGNAVPPPLAKAIGL

DNMT1

1576

P26358
PYKNPNLPLAAIIGG

FLRT3

521

Q9NZU0
LAQPGLPGLVLPYKY

CDT1

176

Q9H211
PEGPNGPNIQKLLYQ

TP53BP2

741

Q13625
PLGPVPLTKEQLYQQ

CNOT3

601

O75175
NVVQYLLPGGIPKSP

MSANTD2

406

Q6P1R3
PLRIPGGNIYISPLK

RB1

796

P06400
NNKPGLLGEPPAVVL

RAVER2

431

Q9HCJ3
LKPIIPNLLPQGAGE

PCDHB5

766

Q9Y5E4
LAPYHPIKPQGVLVL

NPTX1

341

Q15818
GAAFLPVLNGVLPKP

CAPN15

76

O75808
PPSYGQLIAQGLIPP

LRP12

546

Q9Y561
GTQPGPLLKKPYQPR

ITIH5

656

Q86UX2
GTPGPILIPKQALAF

KMT5C

421

Q86Y97
GAVGVPLYAPTPLLQ

HHEX

11

Q03014
VGLPAPAPVINSKYG

KMT5B

336

Q4FZB7
LVGGLPLPPQLYRLQ

DDX59

306

Q5T1V6
LPLGVKLPVIPGSNA

FSIP2

51

Q5CZC0
KFLPGQGLVLYPQIG

EFNB2

41

P52799
LEGGLPQLYPLRPLQ

GPR153

366

Q6NV75
HLLPILYLNGVVGPP

DLG5

81

Q8TDM6
PSYGQLIAQGLIPPV

LRP3

551

O75074
ALRGLQGQPPALFKP

AP5B1

296

Q2VPB7
GPNAKINYLLGPDAP

PCDH11X

496

Q9BZA7
KEYPLGRILIGGNLP

PADI3

421

Q9ULW8
QLAVPGAYEKPQLLP

PLA2G4F

206

Q68DD2
QVVIYLRKGPLIGPP

PTPRO

506

Q16827
LLLMGSYLGKPGPPQ

POM121C

121

A8CG34
QAAVLKEGLPQVYPP

PGR

526

P06401
FKPYIPLIQGLRNPG

DNAH1

1091

Q9P2D7
VAPGKRPALPVQLQY

HYLS1

56

Q96M11
LKPALLAGQPLVYVP

E2F7

536

Q96AV8
KQLALAGLFPYQPPP

CEBPA

171

P49715
QAGAYYGIKPLPPQI

COL8A1

26

P27658
PVKQELPPYNGFGLV

EFHC1

376

Q5JVL4
VYQLLPPGIVSGQPG

IRF9

111

Q00978
LAQQYLPLPTPKVIG

HSPA13

21

P48723
LQNADPLKVYPPLKG

CD74

146

P04233
KLVLGRGLYPQLAVP

DHX34

801

Q14147
GYNRLVNIVPKKPPL

PPHLN1

26

Q8NEY8
APPQLLGVGPTYLLI

PTPRK

296

Q15262
PLGDQPFAGLLPKNL

RPUSD3

56

Q6P087
LIGQIKPELYQGTGP

SYT3

266

Q9BQG1
ILKGGRFYQVPVPLP

MRPS7

161

Q9Y2R9
PLAYILLPGMGKPQL

SOX21

251

Q9Y651
YIPPVLQLSGGQKPD

TEX14

801

Q8IWB6
AQVNPLYKLGPKLAP

SOCS5

291

O75159
PQGLAYALLAGLPPV

SLC26A6

106

Q9BXS9
NPNVNKIPGILDPYL

MYH15

686

Q9Y2K3
NKGQPYRLSPPVLPL

NSUN7

461

Q8NE18
GLGPKVELPLYNQPS

NCOR1

256

O75376
QLLGAPRGKPIFPVY

SOWAHB

721

A6NEL2
QHNYPGIKLQIGPIP

CKAP2L

656

Q8IYA6
GPGNQYLKIQPGAVP

PLPPR4

496

Q7Z2D5
VGIYNLVQKALKPPP

XRCC6

271

P12956
VPPLLHNQYLVGPGG

UBAP2

801

Q5T6F2
NPQGPPLNYALLLIG

TEP1

696

Q99973
LIDLYGNQGLPPPGL

MITF

261

O75030
KNGYPLPEGLPPTLQ

REPS2

351

Q8NFH8
QGLIVPDNPPYNKGA

UBE2L5

36

A0A1B0GUS4
QGTPPKVQLPLNVYL

SH3RF3

456

Q8TEJ3
PGGPILGYNLRLISK

ROS1

221

P08922
QPGLLLLIILAPGPY

TMEM86B

121

Q8N661
VPAAKGLVVGLQPLP

ZBTB42

251

B2RXF5
KYQRNLPRPGQAPIG

ZNF207

381

O43670
GNPGYIVGKPLLALT

TCTN3

381

Q6NUS6
RQYGPNVPEPILQKL

VWA8

941

A3KMH1
LLKGGVIYPALPQPN

TMLHE

16

Q9NVH6
YPAPNGDPILQLLEG

UNC13D

1046

Q70J99
LVLVLPIQAFPKPGG

SCG3

11

Q8WXD2
QGAYGLALKVATPPP

TNS2

1171

Q63HR2
GPEPLPPKGLQYLVL

ZNF692

71

Q9BU19