Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionextracellular matrix structural constituent

ABI3BP MUC17 COL27A1 DMBT1 MUC2 MUC3A AGRN

1.23e-05188827GO:0005201
GeneOntologyMolecularFunctionextracellular matrix constituent, lubricant activity

MUC17 MUC3A

9.94e-054822GO:0030197
GeneOntologyMolecularFunctionstructural molecule activity

DLGAP1 ABI3BP MAP4 MUC17 COL27A1 DAG1 LMNB2 DMBT1 MUC2 MUC3A AGRN MRPL35

2.70e-048918212GO:0005198
GeneOntologyMolecularFunctionlaminin binding

SSC5D DAG1 AGRN

3.64e-0434823GO:0043236
GeneOntologyBiologicalProcessdendrite development

NEDD4L ABI3BP HECW2 ZNF212 ULK4 AFDN RTN4IP1 NLGN1 RERE NCK2

8.48e-073358210GO:0016358
GeneOntologyBiologicalProcessneuron projection development

EVL NEDD4L NRXN1 ABI3BP TRIO MAP4 MYO7A HECW2 ZNF212 DAG1 ULK4 AFDN RTN4IP1 NLGN1 RERE AGRN NCK2

9.82e-0612858217GO:0031175
GeneOntologyBiologicalProcessregulation of presynaptic active zone assembly

NRXN1 NLGN1

1.56e-052822GO:1905518
GeneOntologyBiologicalProcesspositive regulation of presynaptic active zone assembly

NRXN1 NLGN1

1.56e-052822GO:1905520
GeneOntologyBiologicalProcesscell-cell adhesion involved in synapse maturation

NRXN1 NLGN1

1.56e-052822GO:0090125
GeneOntologyBiologicalProcessnegative regulation of sodium ion transmembrane transporter activity

NEDD4L HECW2 AGRN

3.27e-0516823GO:2000650
GeneOntologyBiologicalProcesscell morphogenesis involved in neuron differentiation

EVL NEDD4L NRXN1 ABI3BP TRIO MYO7A HECW2 DAG1 AFDN NLGN1 RERE AGRN

3.82e-057488212GO:0048667
GeneOntologyBiologicalProcessnegative regulation of sodium ion transmembrane transport

NEDD4L HECW2 AGRN

3.96e-0517823GO:1902306
GeneOntologyBiologicalProcessregulation of neuromuscular synaptic transmission

NRXN1 NLGN1

4.67e-053822GO:1900073
GeneOntologyBiologicalProcesspositive regulation of neuromuscular synaptic transmission

NRXN1 NLGN1

4.67e-053822GO:1900075
GeneOntologyBiologicalProcessregulation of NMDA receptor activity

NRXN1 RASGRF2 NLGN1

4.73e-0518823GO:2000310
GeneOntologyBiologicalProcessneuron development

EVL NEDD4L NRXN1 ABI3BP TRIO MAP4 MYO7A HECW2 ZNF212 DAG1 ULK4 AFDN RTN4IP1 NLGN1 RERE AGRN NCK2

5.18e-0514638217GO:0048666
GeneOntologyBiologicalProcesscell morphogenesis

EVL DLC1 NEDD4L NRXN1 ABI3BP TRIO MYO7A HECW2 COL27A1 DAG1 AFDN NLGN1 RERE MUC3A AGRN

6.44e-0511948215GO:0000902
GeneOntologyBiologicalProcessregulation of neurotransmitter receptor activity

DLGAP1 NRXN1 RASGRF2 NLGN1

7.28e-0556824GO:0099601
GeneOntologyBiologicalProcessregulation of postsynaptic density assembly

NRXN1 ABI3BP NLGN1

7.65e-0521823GO:0099151
GeneOntologyBiologicalProcessnegative regulation of sodium ion transport

NEDD4L HECW2 AGRN

8.83e-0522823GO:0010766
GeneOntologyBiologicalProcesspositive regulation of presynapse assembly

NRXN1 NLGN1

9.32e-054822GO:1905608
GeneOntologyBiologicalProcesscell projection morphogenesis

EVL NEDD4L NRXN1 ABI3BP TRIO HECW2 DAG1 AFDN NLGN1 RERE MUC3A AGRN

9.89e-058268212GO:0048858
GeneOntologyBiologicalProcessdendrite morphogenesis

NEDD4L ABI3BP HECW2 AFDN NLGN1 RERE

1.39e-04198826GO:0048813
GeneOntologyBiologicalProcessregulation of postsynaptic specialization assembly

NRXN1 ABI3BP NLGN1

1.47e-0426823GO:0099150
GeneOntologyBiologicalProcessregulation of excitatory synapse assembly

NRXN1 ABI3BP NLGN1

1.47e-0426823GO:1904889
GeneOntologyBiologicalProcessretrograde trans-synaptic signaling by trans-synaptic protein complex

DAG1 NLGN1

1.55e-045822GO:0098942
GeneOntologyBiologicalProcesspresynaptic active zone assembly

NRXN1 NLGN1

1.55e-045822GO:1904071
GeneOntologyBiologicalProcessregulation of postsynaptic density organization

NRXN1 ABI3BP NLGN1

1.65e-0427823GO:1905874
GeneOntologyBiologicalProcessregulation of cell junction assembly

DLC1 NEDD4L NRXN1 ABI3BP AFDN NLGN1 AGRN

2.30e-04309827GO:1901888
GeneOntologyBiologicalProcessNMDA glutamate receptor clustering

NRXN1 NLGN1

2.32e-046822GO:0097114
GeneOntologyBiologicalProcessdendritic spine development

ABI3BP ULK4 AFDN NLGN1 NCK2

2.49e-04141825GO:0060996
GeneOntologyBiologicalProcessmodulation of chemical synaptic transmission

DLGAP1 LRFN2 NRXN1 TRIO RASGRF2 DAG1 KMT2A AFDN NLGN1 AGRN

2.93e-046638210GO:0050804
GeneOntologyBiologicalProcessregulation of trans-synaptic signaling

DLGAP1 LRFN2 NRXN1 TRIO RASGRF2 DAG1 KMT2A AFDN NLGN1 AGRN

2.96e-046648210GO:0099177
GeneOntologyBiologicalProcessprotein localization to cell junction

DLGAP1 NRXN1 DAG1 AFDN NLGN1

3.11e-04148825GO:1902414
GeneOntologyBiologicalProcessneuron projection morphogenesis

EVL NEDD4L NRXN1 ABI3BP TRIO HECW2 DAG1 AFDN NLGN1 RERE AGRN

3.24e-048028211GO:0048812
GeneOntologyBiologicalProcesspostsynaptic density assembly

NRXN1 ABI3BP NLGN1

3.32e-0434823GO:0097107
GeneOntologyBiologicalProcessplasma membrane bounded cell projection morphogenesis

EVL NEDD4L NRXN1 ABI3BP TRIO HECW2 DAG1 AFDN NLGN1 RERE AGRN

3.87e-048198211GO:0120039
GeneOntologyBiologicalProcessneuronal signal transduction

NRXN1 NLGN1

4.30e-048822GO:0023041
GeneOntologyBiologicalProcessregulation of plasma membrane bounded cell projection organization

EVL NEDD4L NRXN1 ABI3BP MAP4 HECW2 ULK4 AFDN RTN4IP1 NLGN1 AGRN

5.08e-048468211GO:0120035
GeneOntologyBiologicalProcesspostsynapse assembly

NRXN1 ABI3BP AFDN NLGN1

5.18e-0493824GO:0099068
GeneOntologyBiologicalProcessregulation of monoatomic ion transmembrane transporter activity

NEDD4L NRXN1 RASGRF2 HECW2 NLGN1 AGRN

5.49e-04256826GO:0032412
GeneOntologyBiologicalProcessregulation of cell projection organization

EVL NEDD4L NRXN1 ABI3BP MAP4 HECW2 ULK4 AFDN RTN4IP1 NLGN1 AGRN

5.99e-048638211GO:0031344
GeneOntologyBiologicalProcesspositive regulation of excitatory postsynaptic potential

NRXN1 AFDN NLGN1

6.66e-0443823GO:2000463
GeneOntologyBiologicalProcessregulation of nervous system process

DLGAP1 NRXN1 DAG1 AFDN NLGN1

6.69e-04175825GO:0031644
GeneOntologyBiologicalProcessregulation of transmembrane transporter activity

NEDD4L NRXN1 RASGRF2 HECW2 NLGN1 AGRN

6.71e-04266826GO:0022898
GeneOntologyBiologicalProcesspresynaptic membrane assembly

NRXN1 NLGN1

6.88e-0410822GO:0097105
GeneOntologyBiologicalProcesspresynaptic active zone organization

NRXN1 NLGN1

6.88e-0410822GO:1990709
GeneOntologyBiologicalProcesspostsynaptic specialization assembly

NRXN1 ABI3BP NLGN1

7.13e-0444823GO:0098698
GeneOntologyBiologicalProcessregulation of neuron projection development

NEDD4L NRXN1 ABI3BP HECW2 ULK4 AFDN RTN4IP1 NLGN1 AGRN

7.17e-04612829GO:0010975
GeneOntologyBiologicalProcessnegative regulation of plasma membrane bounded cell projection assembly

EVL NRXN1 MAP4

7.62e-0445823GO:0120033
GeneOntologyBiologicalProcessregulation of organelle organization

EVL TREX1 EXOSC10 DLC1 NRXN1 ABI3BP MAP4 HECW2 DLGAP5 CEP295 NLGN1 SPECC1L AGRN NCK2

7.73e-0413428214GO:0033043
GeneOntologyBiologicalProcessregulation of cellular component biogenesis

EVL DLC1 NEDD4L NRXN1 ABI3BP MAP4 DAG1 ULK4 AFDN CEP295 NLGN1 AGRN NCK2

7.91e-0411898213GO:0044087
GeneOntologyBiologicalProcessexcitatory synapse assembly

NRXN1 ABI3BP NLGN1

8.13e-0446823GO:1904861
GeneOntologyBiologicalProcesspostsynaptic density protein 95 clustering

NRXN1 NLGN1

8.39e-0411822GO:0097119
GeneOntologyBiologicalProcesspostsynaptic membrane assembly

NRXN1 NLGN1

8.39e-0411822GO:0097104
GeneOntologyBiologicalProcesstrans-synaptic signaling by trans-synaptic complex

DAG1 NLGN1

8.39e-0411822GO:0099545
GeneOntologyBiologicalProcessregulation of postsynapse organization

LRFN2 NRXN1 ABI3BP AFDN NLGN1

8.59e-04185825GO:0099175
GeneOntologyBiologicalProcessregulation of synapse organization

LRFN2 NRXN1 ABI3BP DAG1 AFDN NLGN1 AGRN

8.81e-04387827GO:0050807
GeneOntologyBiologicalProcessregulation of synapse structure or activity

LRFN2 NRXN1 ABI3BP DAG1 AFDN NLGN1 AGRN

9.92e-04395827GO:0050803
GeneOntologyBiologicalProcessprotein localization to synapse

DLGAP1 NRXN1 DAG1 NLGN1

1.15e-03115824GO:0035418
GeneOntologyBiologicalProcesspresynaptic membrane organization

NRXN1 NLGN1

1.18e-0313822GO:0097090
GeneOntologyBiologicalProcessregulation of transporter activity

NEDD4L NRXN1 RASGRF2 HECW2 NLGN1 AGRN

1.23e-03299826GO:0032409
GeneOntologyBiologicalProcessregulation of synapse assembly

NRXN1 ABI3BP AFDN NLGN1 AGRN

1.27e-03202825GO:0051963
GeneOntologyBiologicalProcesspostsynaptic membrane organization

NRXN1 NLGN1 AGRN

1.44e-0356823GO:0001941
GeneOntologyCellularComponentGolgi lumen

MUC3B RHBDF2 MUC17 DAG1 MUC16 MUC5B MUC12 MUC2 MUC3A AGRN MUC20

6.25e-131098411GO:0005796
GeneOntologyCellularComponentexternal encapsulating structure

SSC5D FREM2 ABI3BP MUC17 COL27A1 DAG1 MUC5B DMBT1 MUC2 PKHD1L1 AGRN

6.38e-056588411GO:0030312
GeneOntologyCellularComponentprotein complex involved in cell-cell adhesion

NRXN1 NLGN1

2.37e-046842GO:0098635
GeneOntologyCellularComponentcollagen-containing extracellular matrix

SSC5D FREM2 ABI3BP MUC17 COL27A1 DAG1 DMBT1 MUC2 AGRN

2.75e-04530849GO:0062023
GeneOntologyCellularComponentextracellular matrix

SSC5D FREM2 ABI3BP MUC17 COL27A1 DAG1 MUC5B DMBT1 MUC2 AGRN

2.95e-046568410GO:0031012
GeneOntologyCellularComponenthistone deacetylase complex

NCOR2 NRIP1 RERE SRCAP

3.83e-0485844GO:0000118
GeneOntologyCellularComponentactin-based cell projection

MYO7A MUC17 DAG1 NLGN1 PKHD1L1 MUC20

8.95e-04278846GO:0098858
GeneOntologyCellularComponentneuron to neuron synapse

DLGAP1 LRFN2 NRXN1 ABI3BP MAP4 AFDN NLGN1 NCK2

1.20e-03523848GO:0098984
HumanPhenoAbnormal external nose morphology

FREM2 TREX1 NEDD4L TRIO HECW2 COL27A1 KMT2A CEP295 SPECC1L RERE SRCAP RFX7 NEK9 LUZP1

3.78e-059162614HP:0010938
HumanPhenoClinodactyly

NEDD4L TRIO COL27A1 KMT2A CEP295 LMNB2 SPECC1L RERE SRCAP RFX7 LUZP1

5.34e-055742611HP:0030084
HumanPhenoDisordered formal thought process

TREX1 TRIO HECW2 KMT2A NLGN1 RERE SRCAP RFX7 LUZP1

7.34e-05386269HP:0025769
HumanPhenoAbnormal stomach morphology

TREX1 DLC1 NEDD4L RHBDF2 NRXN1 KMT2A MUC5B RERE SRCAP AGRN NEK9 LUZP1

1.13e-047422612HP:0002577
HumanPhenoSyndactyly

FREM2 NEDD4L TRIO KMT2A CEP295 SPECC1L RERE RFX7 NEK9

1.34e-04417269HP:0001159
HumanPhenoClinodactyly of the 5th finger

NEDD4L TRIO COL27A1 KMT2A LMNB2 SPECC1L RERE SRCAP LUZP1

1.42e-04420269HP:0004209
HumanPhenoClinodactyly of hands

NEDD4L TRIO COL27A1 KMT2A LMNB2 SPECC1L RERE SRCAP LUZP1

1.44e-04421269HP:0001157
HumanPhenoDeviation of the 5th finger

NEDD4L TRIO COL27A1 KMT2A LMNB2 SPECC1L RERE SRCAP LUZP1

1.44e-04421269HP:0009179
HumanPhenoLong philtrum

TRIO KMT2A CEP295 SPECC1L RERE SRCAP RFX7 NEK9 LUZP1

1.67e-04429269HP:0000343
HumanPhenoDeviation of finger

NEDD4L TRIO COL27A1 KMT2A LMNB2 SPECC1L RERE SRCAP NEK9 LUZP1

1.73e-045372610HP:0004097
HumanPhenoRadial deviation of finger

NEDD4L TRIO COL27A1 KMT2A LMNB2 SPECC1L RERE SRCAP LUZP1

2.33e-04448269HP:0009466
HumanPhenoFinger clinodactyly

NEDD4L TRIO COL27A1 KMT2A LMNB2 SPECC1L RERE SRCAP LUZP1

2.49e-04452269HP:0040019
HumanPhenoDeviation of the hand or of fingers of the hand

NEDD4L TRIO COL27A1 KMT2A LMNB2 SPECC1L RERE SRCAP NEK9 LUZP1

2.61e-045642610HP:0009484
HumanPhenoRadial deviation of the hand or of fingers of the hand

NEDD4L TRIO COL27A1 KMT2A LMNB2 SPECC1L RERE SRCAP LUZP1

2.67e-04456269HP:0009485
HumanPhenoRestricted or repetitive behaviors or interests

TRIO HECW2 KMT2A NLGN1 RERE SRCAP RFX7 LUZP1

3.38e-04368268HP:0031432
HumanPhenoPerseverative thought

TRIO HECW2 KMT2A NLGN1 RERE SRCAP RFX7 LUZP1

3.98e-04377268HP:0030223
HumanPhenoAvascular necrosis of the capital femoral epiphysis

TREX1 SRCAP NEK9

4.37e-0430263HP:0005743
HumanPhenoFemale pseudohermaphroditism

FREM2 SPECC1L

5.18e-047262HP:0010458
HumanPhenoGeneralized hypertrichosis

KMT2A SRCAP

5.18e-047262HP:0004554
HumanPhenoSelf-injurious behavior

TREX1 TRIO HECW2 RERE RFX7 LUZP1

5.26e-04210266HP:0100716
HumanPhenoDiagnostic behavioral phenotype

TRIO MYO7A HECW2 KMT2A NLGN1 SPECC1L RERE SRCAP RFX7 LUZP1 MTSS2

5.87e-047472611HP:0025783
HumanPhenoWide nasal bridge

FREM2 TRIO COL27A1 KMT2A SPECC1L RERE SRCAP RFX7 LUZP1

6.01e-04508269HP:0000431
HumanPhenoAbnormal 5th finger morphology

NEDD4L TRIO COL27A1 KMT2A LMNB2 SPECC1L RERE SRCAP LUZP1

6.09e-04509269HP:0004207
HumanPhenoHirsutism

TRIO KMT2A LMNB2 RERE SRCAP LUZP1

6.12e-04216266HP:0001007
HumanPhenoAbnormal thought pattern

TRIO HECW2 KMT2A NLGN1 RERE SRCAP RFX7 LUZP1

6.37e-04404268HP:5200269
HumanPhenoGastroesophageal reflux

NEDD4L RHBDF2 NRXN1 KMT2A MUC5B RERE SRCAP AGRN LUZP1

6.84e-04517269HP:0002020
HumanPhenoDental crowding

FREM2 NEDD4L TRIO CEP295 SPECC1L

6.86e-04144265HP:0000678
DomainSEA

MUC3B MUC17 MUC16 MUC12 MUC3A AGRN

5.65e-1023826PS50024
DomainSEA_dom

MUC3B MUC17 MUC16 MUC12 MUC3A AGRN

5.65e-1023826IPR000082
DomainSEA

MUC3B MUC17 MUC16 MUC3A AGRN

2.80e-0914825SM00200
DomainSEA

MUC3B MUC17 MUC16 MUC12 AGRN

3.58e-0822825PF01390
Domain-

MUC17 MUC16 AGRN

3.57e-05158233.30.70.960
DomainSAPAP

DLGAP1 DLGAP5

1.89e-045822IPR005026
DomainGKAP

DLGAP1 DLGAP5

1.89e-045822PF03359
DomainWxxW_domain

MUC5B MUC2

2.82e-046822IPR025155
DomainMucin2_WxxW

MUC5B MUC2

2.82e-046822PF13330
DomainLAM_G_DOMAIN

NRXN1 COL27A1 AGRN

6.16e-0438823PS50025
DomainEGF_1

MUC3B NRXN1 MUC17 MUC12 MUC3A AGRN

8.99e-04255826PS00022
DomainEGF-like_CS

MUC3B NRXN1 MUC17 MUC12 MUC3A AGRN

1.01e-03261826IPR013032
DomainEGF_2

MUC3B NRXN1 MUC17 MUC12 MUC3A AGRN

1.10e-03265826PS01186
DomainWW

TCERG1L NEDD4L HECW2

1.15e-0347823PF00397
DomainTIL

MUC5B MUC2

1.22e-0312822PF01826
DomainC8

MUC5B MUC2

1.22e-0312822PF08742
DomainWW

TCERG1L NEDD4L HECW2

1.22e-0348823SM00456
DomainUnchr_dom_Cys-rich

MUC5B MUC2

1.44e-0313822IPR014853
DomainC8

MUC5B MUC2

1.44e-0313822SM00832
DomainWW_DOMAIN_2

TCERG1L NEDD4L HECW2

1.46e-0351823PS50020
DomainWW_DOMAIN_1

TCERG1L NEDD4L HECW2

1.46e-0351823PS01159
DomainWW_dom

TCERG1L NEDD4L HECW2

1.54e-0352823IPR001202
DomainTIL_dom

MUC5B MUC2

1.67e-0314822IPR002919
DomainRas_G-nucl-exch_fac_CS

RGL1 RASGRF2

1.67e-0314822IPR019804
DomainLaminin_G

NRXN1 COL27A1 AGRN

2.12e-0358823IPR001791
DomainVWD

MUC5B MUC2

2.20e-0316822SM00216
DomainVWF_type-D

MUC5B MUC2

2.20e-0316822IPR001846
DomainVWFD

MUC5B MUC2

2.20e-0316822PS51233
DomainVWD

MUC5B MUC2

2.20e-0316822PF00094
DomainUIM

ANKIB1 USP37

2.78e-0318822PF02809
DomainCTCK_1

MUC5B MUC2

2.78e-0318822PS01185
DomainVWC_out

MUC5B MUC2

3.10e-0319822SM00215
DomainBRCT

MDC1 TP53BP1

3.10e-0319822PF00533
DomainRasGEFN

RGL1 RASGRF2

3.44e-0320822SM00229
DomainEGF_3

MUC3B NRXN1 MUC17 MUC3A AGRN

3.76e-03235825PS50026
DomainEGF

MUC3B NRXN1 MUC17 MUC3A AGRN

3.76e-03235825SM00181
DomainRasGEF_N

RGL1 RASGRF2

3.79e-0321822PF00618
DomainUIM

ANKIB1 USP37

3.79e-0321822SM00726
DomainSRCR

SSC5D DMBT1

3.79e-0321822PF00530
DomainRas-like_Gua-exchang_fac_N

RGL1 RASGRF2

4.15e-0322822IPR000651
DomainRASGEF_NTER

RGL1 RASGRF2

4.15e-0322822PS50212
DomainCT

MUC5B MUC2

4.15e-0322822SM00041
DomainBRCT

MDC1 TP53BP1

4.15e-0322822SM00292
Domain-

MDC1 TP53BP1

4.54e-03238223.40.50.10190
DomainEGF-like_dom

MUC3B NRXN1 MUC17 MUC3A AGRN

4.80e-03249825IPR000742
DomainUIM

ANKIB1 USP37

4.94e-0324822PS50330
DomainSR

SSC5D DMBT1

5.35e-0325822SM00202
Domain-

SSC5D DMBT1

5.35e-03258223.10.250.10
PathwayREACTOME_DEFECTIVE_GALNT3_CAUSES_HFTC

MUC17 MUC16 MUC5B MUC12 MUC3A MUC20

3.95e-1116616M27410
PathwayREACTOME_DEFECTIVE_C1GALT1C1_CAUSES_TNPS

MUC17 MUC16 MUC5B MUC12 MUC3A MUC20

6.08e-1117616M27412
PathwayREACTOME_TERMINATION_OF_O_GLYCAN_BIOSYNTHESIS

MUC17 MUC16 MUC5B MUC12 MUC3A MUC20

4.86e-1023616M556
PathwayREACTOME_DECTIN_2_FAMILY

MUC17 MUC16 MUC5B MUC12 MUC3A MUC20

1.10e-0926616M27483
PathwayREACTOME_DISEASES_ASSOCIATED_WITH_O_GLYCOSYLATION_OF_PROTEINS

MUC17 DAG1 MUC16 MUC5B MUC12 MUC3A MUC20

1.57e-0868617M27303
PathwayREACTOME_TERMINATION_OF_O_GLYCAN_BIOSYNTHESIS

MUC17 MUC16 MUC5B MUC2 MUC20

2.48e-0821615MM15706
PathwayREACTOME_DISEASES_OF_GLYCOSYLATION

MUC17 DAG1 MUC16 MUC5B MUC12 MUC3A AGRN MUC20

1.72e-07143618M27275
PathwayREACTOME_O_LINKED_GLYCOSYLATION_OF_MUCINS

MUC17 MUC16 MUC5B MUC12 MUC3A MUC20

2.60e-0762616M546
PathwayREACTOME_O_LINKED_GLYCOSYLATION

MUC17 DAG1 MUC16 MUC5B MUC12 MUC3A MUC20

4.77e-07111617M27416
PathwayREACTOME_O_LINKED_GLYCOSYLATION_OF_MUCINS

MUC17 MUC16 MUC5B MUC2 MUC20

5.84e-0660615MM15636
PathwayREACTOME_O_LINKED_GLYCOSYLATION

MUC17 DAG1 MUC16 MUC5B MUC2 MUC20

7.31e-06109616MM15164
PathwayREACTOME_DISEASES_OF_METABOLISM

MUC17 DAG1 MUC16 MUC5B MUC12 MUC3A AGRN MUC20

1.14e-05250618M27554
PathwayREACTOME_C_TYPE_LECTIN_RECEPTORS_CLRS

MUC17 MUC16 MUC5B MUC12 MUC3A MUC20

3.05e-05140616M27484
PathwayREACTOME_PROTEIN_PROTEIN_INTERACTIONS_AT_SYNAPSES

DLGAP1 LRFN2 NRXN1 NLGN1

1.98e-0467614MM15327
PathwayREACTOME_NEUREXINS_AND_NEUROLIGINS

DLGAP1 NRXN1 NLGN1

3.50e-0432613MM15326
PathwayWP_DISRUPTION_OF_POSTSYNAPTIC_SIGNALING_BY_CNV

DLGAP1 NRXN1 NLGN1

3.83e-0433613M39875
PathwayREACTOME_PROTEIN_PROTEIN_INTERACTIONS_AT_SYNAPSES

DLGAP1 LRFN2 NRXN1 NLGN1

5.40e-0487614M27617
PathwayWP_ATM_SIGNALING_IN_DEVELOPMENT_AND_DISEASE

MDC1 LMNB2 TP53BP1

1.09e-0347613M39518
Pubmed

Mucin gene expression in human laryngeal epithelia: effect of laryngopharyngeal reflux.

MUC17 MUC16 MUC5B MUC12 MUC2 MUC3A MUC20

1.26e-141885718834073
Pubmed

Large-scale characterization of HeLa cell nuclear phosphoproteins.

EVL NCOR2 CARHSP1 MAP4 MDC1 DLGAP5 SAFB2 KMT2A AFDN RERE RFX7 POLA2 CCDC86 MEF2D TP53BP1

6.04e-10774851515302935
Pubmed

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

NCOR2 DLGAP1 NEDD4L NRXN1 TRIO DLGAP5 SAFB2 AFDN LMNB2 SPECC1L AGRN NEK9 TP53BP1 LUZP1 MTSS2

1.14e-08963851528671696
Pubmed

Differential Expression of MUC12, MUC16, and MUC20 in Patients with Active and Remission Ulcerative Colitis.

MUC16 MUC12 MUC20

1.41e-08385326770020
Pubmed

Genomic organization and structure of the 3' region of human MUC3: alternative splicing predicts membrane-bound and soluble forms of the mucin.

MUC3B MUC17 MUC3A

1.41e-08385310512748
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

KIAA1671 NHSL1 DLC1 NEDD4L TRIO MAP4 CCDC138 KMT2A AFDN RFX7 NEK9 MEF2D LUZP1 MTSS2

2.18e-08861851436931259
Pubmed

SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.

KIAA1671 EXOSC10 MAP4 MDC1 KMT2A AFDN SPECC1L SRCAP NEK9 TP53BP1 LUZP1

1.02e-07549851138280479
Pubmed

Expression of Muc19/Smgc gene products during murine sublingual gland development: cytodifferentiation and maturation of salivary mucous cells.

MUC16 MUC5B MUC2

2.80e-07685319110483
Pubmed

The Nse5/6-like SIMC1-SLF2 complex localizes SMC5/6 to viral replication centers.

NCOR2 EXOSC10 MAP4 ATAD5 MDC1 DLGAP5 SAFB2 KMT2A AFDN CCDC86 MEF2D TP53BP1 LUZP1

5.47e-07954851336373674
Pubmed

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.

KIAA1671 EVL ENDOD1 NCOR2 NRIP1 LRFN2 NEDD4L RHBDF2 ZNF608 TRIO MAP4 ANKIB1 RERE NEK9 NCK2 PDZD2

5.67e-071489851628611215
Pubmed

Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.

NCOR2 EXOSC10 MAP4 MDC1 DLGAP5 SAFB2 ANKIB1 AFDN LMNB2 SRCAP CCDC86 AGRN NEK9 TP53BP1 LUZP1

9.12e-071353851529467282
Pubmed

Distinct nuclear and cytoplasmic assemblies and interactomes of the mammalian CTLH E3 ligase complex.

EXOSC10 MAP4 MUC5B LMNB2 DMBT1 CCDC86

3.58e-0616785635833506
Pubmed

The matrisome: in silico definition and in vivo characterization by proteomics of normal and tumor extracellular matrices.

FREM2 ABI3BP COL27A1 DMBT1 MUC2 AGRN

3.58e-0616785622159717
Pubmed

Activity-independent and subunit-specific recruitment of functional AMPA receptors at neurexin/neuroligin contacts.

NRXN1 NLGN1

5.90e-06285219098102
Pubmed

DNA damage response mediators MDC1 and 53BP1: constitutive activation and aberrant loss in breast and lung cancer, but not in testicular germ cell tumours.

MDC1 TP53BP1

5.90e-06285217546051
Pubmed

Abundance and Significance of Neuroligin-1 and Neurexin II in the Enteric Nervous System of Embryonic Rats.

NRXN1 NLGN1

5.90e-06285228194405
Pubmed

Initiation of transcription of the MUC3A human intestinal mucin from a TATA-less promoter and comparison with the MUC3B amino terminus.

MUC3B MUC3A

5.90e-06285212958310
Pubmed

Neuroligin-1 induces neurite outgrowth through interaction with neurexin-1β and activation of fibroblast growth factor receptor-1.

NRXN1 NLGN1

5.90e-06285222750515
Pubmed

The in vivo dynamic interplay of MDC1 and 53BP1 at DNA damage-induced nuclear foci.

MDC1 TP53BP1

5.90e-06285222677490
Pubmed

Structural basis for synaptic adhesion mediated by neuroligin-neurexin interactions.

NRXN1 NLGN1

5.90e-06285218084303
Pubmed

Dystroglycan-alpha, a dystrophin-associated glycoprotein, is a functional agrin receptor.

DAG1 AGRN

5.90e-0628528205617
Pubmed

Distinct roles of chromatin-associated proteins MDC1 and 53BP1 in mammalian double-strand break repair.

MDC1 TP53BP1

5.90e-06285218158901
Pubmed

Agrin is involved in lymphocytes activation that is mediated by alpha-dystroglycan.

DAG1 AGRN

5.90e-06285216394267
Pubmed

Neurexin-neuroligin cell adhesion complexes contribute to synaptotropic dendritogenesis via growth stabilization mechanisms in vivo.

NRXN1 NLGN1

5.90e-06285220869594
Pubmed

Multiple transcripts of MUC3: evidence for two genes, MUC3A and MUC3B.

MUC3B MUC3A

5.90e-06285210973822
Pubmed

Neuroligin 1: a splice site-specific ligand for beta-neurexins.

NRXN1 NLGN1

5.90e-0628527736595
Pubmed

[Expression of DNA damage checkpoint mediator 1 and p53-binding protein 1 in human esophageal cancer cell lines TE-1, TE-13, and Eca109].

MDC1 TP53BP1

5.90e-06285217884766
Pubmed

MUC3 human intestinal mucin. Analysis of gene structure, the carboxyl terminus, and a novel upstream repetitive region.

MUC3B MUC3A

5.90e-0628529334251
Pubmed

Dissection of synapse induction by neuroligins: effect of a neuroligin mutation associated with autism.

NRXN1 NLGN1

5.90e-06285215797875
Pubmed

A splice code for trans-synaptic cell adhesion mediated by binding of neuroligin 1 to alpha- and beta-neurexins.

NRXN1 NLGN1

5.90e-06285216242404
Pubmed

The direct interaction between 53BP1 and MDC1 is required for the recruitment of 53BP1 to sites of damage.

MDC1 TP53BP1

5.90e-06285218986980
Pubmed

SALM1 controls synapse development by promoting F-actin/PIP2-dependent Neurexin clustering.

LRFN2 NRXN1

5.90e-06285231368584
Pubmed

Neurexin mediates the assembly of presynaptic terminals.

NRXN1 NLGN1

5.90e-06285212796785
Pubmed

Alternative splicing controls selective trans-synaptic interactions of the neuroligin-neurexin complex.

NRXN1 NLGN1

5.90e-06285216846852
Pubmed

Molecular cloning of cDNAs derived from a novel human intestinal mucin gene.

MUC3B MUC3A

5.90e-0628522393399
Pubmed

Associations of distinct variants of the intestinal mucin gene MUC3A with ulcerative colitis and Crohn's disease.

MUC3B MUC3A

5.90e-06285211289722
Pubmed

Silencing of neuroligin function by postsynaptic neurexins.

NRXN1 NLGN1

5.90e-06285217360903
Pubmed

Dynamic assembly and sustained retention of 53BP1 at the sites of DNA damage are controlled by Mdc1/NFBD1.

MDC1 TP53BP1

5.90e-06285216009723
Pubmed

MLL-AF6 fusion oncogene sequesters AF6 into the nucleus to trigger RAS activation in myeloid leukemia.

KMT2A AFDN

5.90e-06285224695851
Pubmed

Study of mucin turnover in the small intestine by in vivo labeling.

MUC17 MUC2

5.90e-06285229636525
Pubmed

[Interleukin-1beta induces MUC2/MUC5B gene expression in human nasal epithelial cells].

MUC5B MUC2

5.90e-06285220873538
Pubmed

Neurexin and Neuroligin-based adhesion complexes drive axonal arborisation growth independent of synaptic activity.

NRXN1 NLGN1

5.90e-06285229504935
Pubmed

Expression of neurexin and neuroligin in the enteric nervous system and their down-regulated expression levels in Hirschsprung disease.

NRXN1 NLGN1

5.90e-06285223264101
Pubmed

Characterization of the interaction of a recombinant soluble neuroligin-1 with neurexin-1beta.

NRXN1 NLGN1

5.90e-06285214522992
Pubmed

Agrin is a high-affinity binding protein of dystroglycan in non-muscle tissue.

DAG1 AGRN

5.90e-0628529417121
Pubmed

Downregulation of MDC1 and 53BP1 by short hairpin RNA enhances radiosensitivity in laryngeal carcinoma cells.

MDC1 TP53BP1

5.90e-06285225976740
Pubmed

The MUC3 gene encodes a transmembrane mucin and is alternatively spliced.

MUC3B MUC3A

5.90e-06285210405327
Pubmed

Identifying biological pathways that underlie primordial short stature using network analysis.

KIAA1671 EXOSC10 NEDD4L MAP4 MDC1 SAFB2 UCK2 AFDN LMNB2 SPECC1L SRCAP CCDC86

7.26e-061024851224711643
Pubmed

MEF2C regulates cortical inhibitory and excitatory synapses and behaviors relevant to neurodevelopmental disorders.

NRXN1 NLGN1 MEF2D

9.35e-061785327779093
Pubmed

Voltage-dependent conformational changes of Kv1.3 channels activate cell proliferation.

NRIP1 MAP4 COL27A1 KMT2A SPECC1L LUZP1

1.26e-0520885633230847
Pubmed

Mutations in the TP53 gene affected recruitment of 53BP1 protein to DNA lesions, but level of 53BP1 was stable after γ-irradiation that depleted MDC1 protein in specific TP53 mutants.

MDC1 TP53BP1

1.77e-05385228397142
Pubmed

Solution structure of AF-6 PDZ domain and its interaction with the C-terminal peptides from Neurexin and Bcr.

NRXN1 AFDN

1.77e-05385215684424
Pubmed

Synaptic Kalirin-7 and Trio Interactomes Reveal a GEF Protein-Dependent Neuroligin-1 Mechanism of Action.

TRIO NLGN1

1.77e-05385231801062
Pubmed

Distinct versus overlapping functions of MDC1 and 53BP1 in DNA damage response and tumorigenesis.

MDC1 TP53BP1

1.77e-05385218504301
Pubmed

53BP1 and NFBD1/MDC1-Nbs1 function in parallel interacting pathways activating ataxia-telangiectasia mutated (ATM) in response to DNA damage.

MDC1 TP53BP1

1.77e-05385214695167
Pubmed

DUSP28 links regulation of Mucin 5B and Mucin 16 to migration and survival of AsPC-1 human pancreatic cancer cells.

MUC16 MUC5B

1.77e-05385227230679
Pubmed

Integrative analysis of the cancer genome atlas and cancer cell lines encyclopedia large-scale genomic databases: MUC4/MUC16/MUC20 signature is associated with poor survival in human carcinomas.

MUC16 MUC20

1.77e-05385230236127
Pubmed

α-Dystroglycan is essential for the induction of Egr3, a transcription factor important in muscle spindle formation.

DAG1 AGRN

1.77e-05385220213761
Pubmed

Expression of mucin 3 and mucin 5AC in arthritic synovial tissue.

MUC3B MUC3A

1.77e-05385218163520
Pubmed

Leukemic transformation by the MLL-AF6 fusion oncogene requires the H3K79 methyltransferase Dot1l.

KMT2A AFDN

1.77e-05385223361907
Pubmed

Recruitment kinetics of DNA repair proteins Mdc1 and Rad52 but not 53BP1 depend on damage complexity.

MDC1 TP53BP1

1.77e-05385222860035
Pubmed

Two atypical enteropathogenic Escherichia coli strains induce the production of secreted and membrane-bound mucins to benefit their own growth at the apical surface of human mucin-secreting intestinal HT29-MTX cells.

MUC17 MUC2

1.77e-05385220065027
Pubmed

RNF168 ubiquitylates 53BP1 and controls its response to DNA double-strand breaks.

MDC1 TP53BP1

1.77e-05385224324146
Pubmed

Dopaminergic neurons establish a distinctive axonal arbor with a majority of non-synaptic terminals.

NRXN1 NLGN1

1.77e-05385234320240
Pubmed

Dynamics of expression patterns of AQP4, dystroglycan, agrin and matrix metalloproteinases in human glioblastoma.

DAG1 AGRN

1.77e-05385222307776
Pubmed

Tyrosine kinase c-Abl couples RNA polymerase II transcription to DNA double-strand breaks.

MDC1 TP53BP1

1.77e-05385230668775
Pubmed

Characteristics of rodent intestinal mucin Muc3 and alterations in a mouse model of human cystic fibrosis.

MUC17 MUC2

1.77e-05385211352827
Pubmed

The menin tumor suppressor protein is an essential oncogenic cofactor for MLL-associated leukemogenesis.

KMT2A AFDN

1.77e-05385216239140
Pubmed

Three-way translocation involving MLL, MLLT1, and a novel third partner, NRXN1, in a patient with acute lymphoblastic leukemia and t(2;19;11) (p12;p13.3;q23).

NRXN1 KMT2A

1.77e-05385220113834
Pubmed

Role of ATM and the damage response mediator proteins 53BP1 and MDC1 in the maintenance of G(2)/M checkpoint arrest.

MDC1 TP53BP1

1.77e-05385220421415
Pubmed

Activity-dependent validation of excitatory versus inhibitory synapses by neuroligin-1 versus neuroligin-2.

NRXN1 NLGN1

1.77e-05385217582332
Pubmed

NFBD1/MDC1, 53BP1 and BRCA1 have both redundant and unique roles in the ATM pathway.

MDC1 TP53BP1

1.77e-05385219001859
Pubmed

Mucin gene polymorphisms in otitis media patients.

MUC5B MUC2

1.77e-05385219718741
Pubmed

Interaction network of human early embryonic transcription factors.

KIAA1671 NCOR2 ZNF608 MDC1 KMT2A RERE RFX7

2.52e-0535185738297188
Pubmed

Proximity biotinylation and affinity purification are complementary approaches for the interactome mapping of chromatin-associated protein complexes.

ZNF608 ATAD5 DLGAP5 CCDC138 KMT2A SRCAP CCDC86 NEK9 LUZP1

2.89e-0564585925281560
Pubmed

MCPH1 functions in an H2AX-dependent but MDC1-independent pathway in response to DNA damage.

MDC1 TP53BP1

3.53e-05485217925396
Pubmed

Increased expression of MUC5AC and MUC5B promoting bacterial biofilm formation in chronic rhinosinusitis patients.

MUC5B MUC2

3.53e-05485225638393
Pubmed

Epigenetic regulation (DNA methylation, histone modifications) of the 11p15 mucin genes (MUC2, MUC5AC, MUC5B, MUC6) in epithelial cancer cells.

MUC5B MUC2

3.53e-05485217471237
Pubmed

Expression of MUC1, MUC2, MUC5AC and MUC5B in mucinous lesions of the breast.

MUC5B MUC2

3.53e-05485222269464
Pubmed

The mouse secreted gel-forming mucin gene cluster.

MUC5B MUC2

3.53e-05485214984930
Pubmed

A role for the deubiquitinating enzyme USP28 in control of the DNA-damage response.

MDC1 TP53BP1

3.53e-05485216901786
Pubmed

Astrocytes Assemble Thalamocortical Synapses by Bridging NRX1α and NL1 via Hevin.

NRXN1 NLGN1

3.53e-05485226771491
Pubmed

Survival kinase genes present prognostic significance in glioblastoma.

ULK4 NEK9

3.53e-05485226956052
Pubmed

Effects of the Helicobacter pylori Virulence Factor CagA and Ammonium Ion on Mucins in AGS Cells.

MUC5B MUC2

3.53e-05485229869461
Pubmed

Replication independent ATR signalling leads to G2/M arrest requiring Nbs1, 53BP1 and MDC1.

MDC1 TP53BP1

3.53e-05485218664457
Pubmed

Polymorphisms in MUC1, MUC2, MUC5B and MUC6 genes are not associated with the risk of chronic atrophic gastritis.

MUC5B MUC2

3.53e-05485221596555
Pubmed

TGF-β1, Ghrelin, Neurexin, and Neuroligin are predictive biomarkers for postoperative prognosis of laparoscopic surgery in children with Hirschsprung disease.

NRXN1 NLGN1

3.53e-05485225399301
Pubmed

Expression of MUC2, MUC5AC, MUC5B, and MUC6 mucins in colorectal cancers and their association with the CpG island methylator phenotype.

MUC5B MUC2

3.53e-05485223807779
Pubmed

Butyrate enemas upregulate Muc genes expression but decrease adherent mucus thickness in mice colon.

MUC17 MUC2

3.53e-05485218198997
Pubmed

MMSET regulates histone H4K20 methylation and 53BP1 accumulation at DNA damage sites.

MDC1 TP53BP1

3.53e-05485221293379
Pubmed

NFBD1, like 53BP1, is an early and redundant transducer mediating Chk2 phosphorylation in response to DNA damage.

MDC1 TP53BP1

3.53e-05485212551934
Pubmed

Characterization of mouse muc6 and evidence of conservation of the gel-forming mucin gene cluster between human and mouse.

MUC5B MUC2

3.53e-05485212676567
Pubmed

Dystroglycan is selectively associated with inhibitory GABAergic synapses but is dispensable for their differentiation.

DAG1 AGRN

3.53e-05485212040032
Pubmed

An agrin minigene rescues dystrophic symptoms in a mouse model for congenital muscular dystrophy.

DAG1 AGRN

3.53e-05485211565031
Pubmed

DNA damage activates ATM through intermolecular autophosphorylation and dimer dissociation.

MDC1 TP53BP1

3.53e-05485212556884
Pubmed

Human transcription factor protein interaction networks.

KIAA1671 NCOR2 ZNF608 ATAD5 MDC1 CCDC138 KMT2A RERE SRCAP RFX7 CCDC86 MEF2D TP53BP1

4.24e-051429851335140242
Pubmed

KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.

NHSL1 EVL DLGAP1 NEDD4L TRIO MAP4 MYO7A HECW2 KMT2A AFDN SPECC1L LUZP1 NCK2

4.30e-051431851337142655
Pubmed

In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.

EVL TCERG1L NRXN1 ABI3BP ZNF608 SBNO1 SAFB2 KMT2A ATP10B CEP295 LMNB2 SRCAP LUZP1

4.65e-051442851335575683
Pubmed

Proximity-dependent Mapping of the Androgen Receptor Identifies Kruppel-like Factor 4 as a Functional Partner.

EXOSC10 ZNF608 MDC1 KMT2A RERE MEF2D

5.20e-0526885633640491
Pubmed

The variant Polycomb Repressor Complex 1 component PCGF1 interacts with a pluripotency sub-network that includes DPPA4, a regulator of embryogenesis.

NCOR2 EXOSC10 MDC1 MUC16 POLA2 CCDC86 TP53BP1

5.42e-0539685726687479
InteractionNRXN1 interactions

DLGAP1 NRXN1 MAP4 DAG1 SLC39A6 AFDN NLGN1 PDZD2

5.29e-08127838int:NRXN1
InteractionWWTR1 interactions

KIAA1671 EXOSC10 KMT2A AFDN RTN4IP1 SPECC1L SRCAP NEK9 TP53BP1 LUZP1

9.07e-064228310int:WWTR1
InteractionYWHAH interactions

KIAA1671 NHSL1 NRIP1 DLGAP1 NEDD4L RHBDF2 TRIO CCDC138 KMT2A AFDN SPECC1L RFX7 POLA2 MEF2D LUZP1 MTSS2

9.26e-0611028316int:YWHAH
InteractionZZZ3 interactions

ZNF608 HECW2 ZNF212 KMT2A RERE TP53BP1

2.36e-05139836int:ZZZ3
InteractionTNIK interactions

NCOR2 DLGAP1 NEDD4L TRIO LMNB2 AGRN TP53BP1 NCK2 MTSS2

2.69e-05381839int:TNIK
InteractionKAT8 interactions

ZNF608 HECW2 KMT2A RERE TP53BP1

4.55e-0595835int:KAT8
InteractionYWHAQ interactions

KIAA1671 NHSL1 NRIP1 DLGAP1 NEDD4L NRXN1 MAP4 KMT2A ULK4 AFDN SPECC1L RFX7 MEF2D LUZP1 MTSS2

4.59e-0511188315int:YWHAQ
InteractionFAM47A interactions

FAM47A NCK2

5.01e-053832int:FAM47A
InteractionMAP2 interactions

NEDD4L NRXN1 MYO7A HECW2 DAG1

7.01e-05104835int:MAP2
Cytoband7q22

MUC3B MUC12 MUC3A

4.93e-05388537q22
CytobandEnsembl 112 genes in cytogenetic band chr3p21

TREX1 MAP4 SHISA5 DAG1 CCR3

3.13e-04316855chr3p21
Cytoband19p13.3

ZNF556 SAFB2 LMNB2 FUT3

1.01e-0323785419p13.3
GeneFamilyCD molecules|Mucins

MUC3B MUC17 MUC16 MUC5B MUC12 MUC2 MUC3A MUC20

5.27e-1621528648
CoexpressionNABA_ECM_AFFILIATED

FREM2 MUC17 MUC16 MUC5B MUC12 MUC2 MUC3A MUC20

7.61e-08170848M5880
CoexpressionLAKE_ADULT_KIDNEY_C3_PROXIMAL_TUBULE_EPITHELIAL_CELLS_S1_S2

NEDD4L SAFB2 ANKIB1 ULK4 AFDN NLGN1 RERE PDZD2

5.66e-07221848M39222
CoexpressionNABA_ECM_AFFILIATED

FREM2 MUC17 MUC16 MUC5B MUC2 MUC20

1.20e-05158846MM17063
CoexpressionNABA_MATRISOME

FREM2 FNDC1 ABI3BP MUC17 COL27A1 MUC16 MUC5B MUC12 DMBT1 MUC2 MUC3A AGRN MUC20

2.23e-0510268413M5889
CoexpressionE2F1_UP.V1_UP

EVL DLGAP5 UCK2 DMBT1 POLA2 MTSS2

3.21e-05188846M2632
CoexpressionHE_LIM_SUN_FETAL_LUNG_C0_PERICYTE

ENDOD1 DBNDD2 AGRN NCK2 MTSS2 PDZD2

3.94e-05195846M45684
CoexpressionGSE23502_BM_VS_COLON_TUMOR_MYELOID_DERIVED_SUPPRESSOR_CELL_DN

ZNF608 ATAD5 SHISA5 MDC1 RFX7 NCK2

4.54e-05200846M8088
CoexpressionGSE21380_NON_TFH_VS_GERMINAL_CENTER_TFH_CD4_TCELL_DN

MAP4 SBNO1 MDC1 SRCAP RFX7 MEF2D

4.54e-05200846M7505
ToppCellnucseq-Epithelial-Epithelial_Glandular|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

MUC17 MUC16 ATP10B MUC5B FUT3 MUC3A MUC20

4.91e-08179847859cd8ee414ad6207c046ada2e655e49322dd01c
ToppCellnucseq-Epithelial-Epithelial_Glandular-Goblet|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

MUC17 MUC16 ATP10B MUC5B FUT3 MUC3A MUC20

5.10e-081808473dc80bc636bf0e6ffc9762853132a9fe59fd1f66
ToppCellnucseq-Epithelial-Epithelial_Glandular-Goblet-Goblet|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

MUC17 MUC16 ATP10B MUC5B FUT3 MUC3A MUC20

5.10e-08180847668a2d8e1d5a390309d5eb62c836f5903144bea9
ToppCelldistal-3-Epithelial-Goblet|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

MUC16 ATP10B MUC5B FUT3 MUC2 STPG2 MUC20

9.44e-08197847a00784ccfb1de6a96b91e2a8a2889b69f31a33da
ToppCellLPS_only-Endothelial-Endothelial-Activated_Alv_Cap|LPS_only / Treatment groups by lineage, cell group, cell type

DLC1 ZNF608 CARHSP1 HECW2 KMT2A AFDN LUZP1

1.05e-07200847edb64556b3fefe3144f73b6efe23b9ffd34091d2
ToppCellControl|World / group, cell type (main and fine annotations)

FREM2 DLGAP1 DLC1 NEDD4L DMBT1 PDZD2

7.92e-07168846a3511faf2cd2c2b9c8363c8b99da3f3609c43ed6
ToppCellControl-Epithelial_cells-Airway_mucous|Control / group, cell type (main and fine annotations)

MUC17 MUC16 ATP10B MUC5B FUT3 MUC3A

1.30e-0618384615d24a4fb1ffe6cbafbd54fcd7dde9ddcfbe03b2
ToppCellCOVID-19-Epithelial_cells-AT2|COVID-19 / group, cell type (main and fine annotations)

FREM2 DLGAP1 NEDD4L NLGN1 DMBT1 PDZD2

1.35e-06184846369b82f793deab672204558ae4e112cfa5aa9ccc
ToppCellControl-Epithelial_cells-Airway_goblet|Control / group, cell type (main and fine annotations)

MUC17 MUC16 ATP10B MUC5B FUT3 MUC3A

1.35e-06184846d92a71441e4e19f8c301999d8186f8e48e3cd162
ToppCell3'-Airway_Nasal-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell-Deuterosomal-Deuterosomal_L.0.3.4.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CARHSP1 DLGAP5 MUC16 FAM227A CEP295 MUC12

1.62e-061908460adb24dafa077156bbc73a8d8cbf3d9eeb6e08df
ToppCell3'-Airway_Nasal-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell-Deuterosomal|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CARHSP1 DLGAP5 MUC16 FAM227A CEP295 MUC12

1.62e-0619084605455775845f4ded5c27e7b83242078d23162aaf
ToppCellpdx-Tumor_cells-T1|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)

ATAD5 MDC1 DLGAP5 CCDC138 CEP295 POLA2

1.62e-06190846d06ee5f89f1cec8db6897fe3b2a890a07cd3697b
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

NHSL1 FREM2 DLC1 NEDD4L ZNF608 PDZD2

1.67e-06191846ca5669bd6f4a17471acae3eb229f845cc2e08efa
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

NHSL1 FREM2 DLC1 NEDD4L DMBT1 PDZD2

1.72e-06192846fb2f0e897228f808d9ff734ad05e9b49dc38fa50
ToppCellhuman_hepatoblastoma-Tumor_cells-T1|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)

ATAD5 MDC1 DLGAP5 CCDC138 CEP295 POLA2

1.77e-061938464b9fa2a4424f8abe63fa7bee78db93dda04ab15f
ToppCellhuman_hepatoblastoma-Tumor_cells|human_hepatoblastoma / Sample and Cell Type and Tumor Cluster (all cells)

DLGAP1 NEDD4L COL27A1 AFDN STPG2 MTSS2

1.77e-06193846503a979328c68b096680b71359a26f02fafdff35
ToppCellParenchymal-10x5prime-Epithelial-Epi_submucosal-gland-SMG_Duct|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

MUC16 FAM227A MUC5B FUT3 MUC20

1.93e-061088459c7f3e25facfb54ef0be45044999bc36438bbea0
ToppCellParenchymal-10x5prime-Epithelial-Epi_submucosal-gland|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

MUC16 FAM227A MUC5B FUT3 MUC20

1.93e-0610884575d635fc5bb004418db2e1328c24d96b718f10b1
ToppCelldistal-Epithelial-Goblet|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

MUC16 ATP10B MUC5B FUT3 MUC2 MUC20

2.00e-06197846da1ed7303cc9cb2d205c0e5c49c52544d3540951
ToppCellAT2_cells-IPF_03|World / lung cells shred on cell class, cell subclass, sample id

COL27A1 ATP10B MUC5B DMBT1 MUC3A AGRN

2.00e-061978465e0d222872a25bb9e9069d3dffda2844bb69874a
ToppCelldistal-Epithelial-Goblet-3|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

MUC16 ATP10B MUC5B FUT3 MUC2 MUC20

2.00e-061978463fbf456ae4f73da4f6254a6f0d24f0ec27d7a3cc
ToppCellTracheal-10x5prime-Epithelial-Epi_submucosal-gland-SMG_Duct|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

NEDD4L MUC16 ATP10B MUC5B DMBT1 MUC20

2.12e-06199846ef1a0c278c23614fd6a3218a9733abe6ecd6f686
ToppCellLPS_IL1RA-Endothelial-Endothelial|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

DLC1 ZNF608 CARHSP1 MAP4 AFDN LUZP1

2.18e-0620084672ea9882a8ed26fa1534aeb6ba0d1897dccc20c5
ToppCellLPS_only-Endothelial-Endothelial-Activated_Gen_Cap|LPS_only / Treatment groups by lineage, cell group, cell type

DLC1 ZNF608 CARHSP1 KMT2A AFDN LUZP1

2.18e-062008466f531a418ff25b59a543800cf4bce7b72404ce08
ToppCellLPS_IL1RA-Endothelial-Endothelial-Activated_Gen_Cap|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

DLC1 ZNF608 CARHSP1 KMT2A AFDN LUZP1

2.18e-062008462d07237022b409c4fac6fcf99b68c8affb3007cd
ToppCellLPS_IL1RA-Endothelial|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

DLC1 ZNF608 CARHSP1 MAP4 AFDN LUZP1

2.18e-062008465c092b2ecc081b5d04476c56333c338cd89ab984
ToppCellfacs-Brain_Non-Myeloid-Cerebellum_-18m-Epithelial-neuronal_stem_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SSC5D ATAD5 DLGAP5 CCDC138 POLA2

1.92e-05173845f38bf7584e08d15a6e2c116b7c3551ba475a5e14
ToppCell(03)_Secretory-(0)_uninjured|(03)_Secretory / shred by cell type and Timepoint

ENDOD1 MUC16 MUC5B DMBT1 MUC20

1.97e-05174845ebdddb5091afcc49ab533c890f260f709880c5f9
ToppCellfacs-Marrow-Granulocytes-3m-Myeloid-basophil|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HECW2 CCR3 NLGN1 NCK2 MUC20

2.02e-051758451b35acece23712ab7e3f92d9d68266efd38b3ef5
ToppCelldroplet-Kidney-KIDNEY-30m-Mesenchymal-podocyte|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABI3BP ZNF608 ULK4 MUC5B TP53BP1

2.02e-0517584531f0fb2e47e357dbf9c15436b7df85b3c370ded7
ToppCellfacs-Marrow-Granulocytes-3m-Myeloid-basophil|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HECW2 CCR3 NLGN1 NCK2 MUC20

2.02e-05175845a9f88054e2c28d604c65ed785f63021aadb7f4c8
ToppCell3'-GW_trimst-1.5-SmallIntestine-Epithelial-epithelial_progenitor_cell-Proximal_progenitor|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

KIAA1671 MUC17 ATP10B DMBT1 MUC3A

2.32e-051808458d9be9cfdf98e5888654a28ab12e5e89f201af00
ToppCellControl-Epithelial_cells-AT2|Control / group, cell type (main and fine annotations)

FREM2 DLGAP1 DLC1 NEDD4L DMBT1

2.32e-05180845198b19e7910b4a8cc7e820c525ab357c7f99f578
ToppCelldroplet-Limb_Muscle-nan-21m-Macroglial-nan|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DLGAP1 VXN DAG1 NLGN1 MTSS2

2.44e-05182845a512863304fad80acaab60a8c6107eb7c9cbac99
ToppCelldroplet-Limb_Muscle-MUSCLE-1m-Macroglial-unknown|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DLGAP1 NRXN1 COL27A1 VXN DAG1

2.44e-0518284582ca6d5ed48b4c487ce00b9309255abb8f20b61d
ToppCelldroplet-Limb_Muscle-nan-21m-Macroglial|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DLGAP1 NRXN1 VXN DAG1 MTSS2

2.64e-051858453d1353dbcb60e2531ef67e1bd218b7bc4d7c7c9b
ToppCelldroplet-Limb_Muscle-nan-21m-Macroglial-Schwann_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DLGAP1 NRXN1 VXN DAG1 MTSS2

2.64e-05185845995a8ddc3fd8e6879d8b5de8cbdefe232d34833b
ToppCelldroplet-Limb_Muscle-nan-24m-Macroglial-nan|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DLGAP1 NRXN1 DBNDD2 DAG1 NLGN1

2.71e-05186845adba5647a2feaba8e361dc1020d2f2dc4ce36b16
ToppCellpdx|World / Sample and Cell Type and Tumor Cluster (all cells)

DLGAP1 RASGRF2 COL27A1 CCDC138 RERE

2.71e-05186845de8e538c8767d41b8a52f5e58ba1affd4e7244c4
ToppCellpdx-Tumor_cells|World / Sample and Cell Type and Tumor Cluster (all cells)

DLGAP1 RASGRF2 COL27A1 CCDC138 RERE

2.71e-051868450b88a87158a9ca8de3bf40a4ff1687150707a5f0
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_3|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

KIAA1671 ENDOD1 NLGN1 FUT3 PDZD2

2.71e-05186845b1edc341d6684b347dc9e21b34f62f51d095d735
ToppCell15-Trachea-Epithelial-Secretory_progenitor|Trachea / Age, Tissue, Lineage and Cell class

DLC1 COL27A1 SLC39A6 MUC5B AGRN

2.78e-05187845be9fce9e74b2f170a2067f1b31d802912a578329
ToppCell3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MUC16 ATP10B MUC5B DMBT1 FUT3

2.78e-0518784571d99a1a95d3692a2891da49d4a243bae6e07fd0
ToppCell-Unknown-Endothelial-Myofibroblast| / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

RGL1 ABI3BP KMT2A SPECC1L LUZP1

2.85e-051888456468fa95ad0395395301115286f2d8c0df5d3882
ToppCell-Unknown-Endothelial| / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

RGL1 ABI3BP KMT2A SPECC1L LUZP1

2.85e-051888457a81ac5c79c3eb26639b52d2b9fd5e7ef9798fd6
ToppCell-Unknown| / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

RGL1 ABI3BP KMT2A SPECC1L LUZP1

2.85e-051888459cb718bfe1358c6fd842f096e228eb0abb9aefc6
ToppCellFetal_29-31_weeks-Endothelial-endothelial_cell_of_lymph_vessel-D062|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

KIAA1671 ENDOD1 RASGRF2 HECW2 PKHD1L1

2.93e-051898450d18ea72bd58d32a8ab9a61cf97f5786642f804b
ToppCellfacs-Lung-nan-3m-Endothelial-Capillary_Aerocyte_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RGL1 ENDOD1 FNDC1 VXN SLC39A6

2.93e-0518984509dd2b3d89416192e84abe302a6237b8f3fdcb6e
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

DLGAP1 ABI3BP TRIO COL27A1 NLGN1

2.93e-051898453b48b0d220cc24d5170713d61fa91f5bb6c21841
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

NHSL1 FREM2 DLC1 NEDD4L ZNF608

3.00e-051908458aea807a2bcf0b653b4de6202b6ecb0f0683cc2e
ToppCellLPS_only-Endothelial-Endothelial-Alv_Cap|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

KIAA1671 ZNF608 CARHSP1 HECW2 AFDN

3.00e-05190845474cbbab8f3b0a6881fa6c92edb78e43999f9ab0
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

KIAA1671 DLGAP1 NEDD4L NLGN1 PDZD2

3.08e-051918453c464645d0e7e423f791bd63bf5bcf11f6b590d3
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

KIAA1671 DLGAP1 NEDD4L NLGN1 PDZD2

3.08e-051918451c1d13144259b998d4a0e85142f7afef2ef1e63f
ToppCellControl-Stromal_mesenchymal|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SSC5D DLGAP1 FNDC1 ABI3BP COL27A1

3.08e-0519184514057205ddb9b4bbc582d1358d13cf36d979a61b
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

DLGAP1 ZNF608 TRIO COL27A1 NLGN1

3.08e-051918451cb02007adb344f17ef73d58890f91298c7cf5a1
ToppCellEpithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)|World / Lineage, Cell type, age group and donor

FREM2 DLC1 NEDD4L ZNF608 AFDN

3.08e-05191845d3733c8c4bda70c4390e5601fdda6188a64be944
ToppCellChildren_(3_yrs)-Epithelial|Children_(3_yrs) / Lineage, Cell type, age group and donor

FREM2 DLC1 NEDD4L ZNF608 PDZD2

3.08e-05191845e432c6e1ae82dddf84314ce73d2b7a991630d905
ToppCellEpithelial-alveolar_epithelial_cell_type_2|World / Lineage, Cell type, age group and donor

FREM2 DLC1 NEDD4L DMBT1 PDZD2

3.16e-0519284558c3737be7acce39fd2b91d70d6d7b2bbaa4f710
ToppCellLPS-IL1RA-Endothelial-Endothelial-Activated_Alv_Cap|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

NEDD4L CARHSP1 HECW2 AFDN LUZP1

3.23e-05193845a3636c35ed25aabe2f1aba016c9fe125327bbfaf
ToppCell10x5'-GI_small-bowel|World / Manually curated celltypes from each tissue

EVL MUC17 MUC12 DMBT1 MUC3A

3.23e-05193845cd89dfe53a114078f06343049685883c8e26508f
ToppCell5'-Adult-SmallIntestine-Epithelial-mature_enterocytic-Paneth|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

NHSL1 MUC17 DMBT1 MUC2 MUC3A

3.32e-051948452f6e62a4ec8707bd5a16c0734c5131af55207ea2
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

DLGAP1 NEDD4L AFDN NLGN1 STPG2

3.32e-051948457002937e8903e037332a215d00fbc7c7843b33f2
ToppCellnucseq-Epithelial-Epithelial_Alveolar|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

FREM2 DLC1 NEDD4L AFDN PDZD2

3.32e-0519484553f3e49e91b1096f3226010e2de767efb490dfe4
ToppCellcellseq-Epithelial-Epithelial_Glandular|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

MUC16 ATP10B MUC5B DMBT1 FUT3

3.32e-05194845d0fb1ff5cf0738881e114a58f0b27489f781d72b
ToppCellLPS-IL1RA-Endothelial-Endothelial-Gen_Cap|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

KIAA1671 DLC1 ZNF608 HECW2 AFDN

3.32e-051948450b9cd96fa0b616da7cc90e92ff71157e9bba518f
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22-Lymphocytic-Lymphocytic_B-Plasma_cell-B_c06-MKI67|Severe-critical_progression_d12-22 / Compartment, severity and other cell annotations on 10x 3' data (130k)

DLGAP5 UCK2 CCDC86 PKHD1L1 MRPL35

3.32e-051948455771a28a61f4d9b5479891f3224909ab003cb241
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

NEDD4L AFDN NLGN1 RERE STPG2

3.40e-051958456477e6e7be5bd8eb99119a12ae16334ccddecd43
ToppCellMild-CD8+_T_activated|World / Disease group and Cell class

EVL ENDOD1 TREX1 SHISA5 SLA2

3.48e-0519684579632190e44fcef9d7c11d9b9e37f2ebf0e6e255
ToppCellParenchymal-10x5prime-Stromal-Mesofibroblastic|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

FNDC1 ABI3BP MUC16 ATP10B PKHD1L1

3.57e-0519784588a86286b9c3ea3b076d7464faec42d0392ee7f8
ToppCellParenchymal-10x5prime-Stromal-Mesofibroblastic-Mesothelia|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

FNDC1 ABI3BP MUC16 ATP10B PKHD1L1

3.57e-051978452773d2eb5f232a7e49da116efffcb6bf5eb90810
ToppCellcellseq2-Epithelial-Epithelial_Glandular-SMG_Basal/Duct-SMG_Basal/Duct|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

CARHSP1 MUC16 AFDN AGRN MUC20

3.65e-05198845829377071f65016d31d09175a43c28e95532b404
ToppCellwk_08-11-Epithelial-Airway_epithelial_progenitor-epi-prox-progenitor_intermediate_|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

ENDOD1 FREM2 NEDD4L ZNF608 MUC20

3.65e-051988451eb49b853a9e144e840c660060473fc7873f6478
ToppCellcellseq2-Epithelial-Epithelial_Glandular-SMG_Basal/Duct|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

CARHSP1 MUC16 AFDN AGRN MUC20

3.65e-0519884527a3c1c5ac855dff8d63f44eaa289be3f5bd621a
ToppCellControl_saline-Mesenchymal_fibroblastic-Fibroblasts-Activated_MatrixFB|Control_saline / Treatment groups by lineage, cell group, cell type

NRXN1 ABI3BP MYO7A COL27A1 SPECC1L

3.65e-051988450c4d2c68a42f8a9e964e2dd28092fe75f5216834
ToppCellNS-critical-d_07-13|critical / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

NEDD4L MUC16 ATP10B FUT3 MUC20

3.65e-05198845a6e11c87b31beffb6af190c64b4ef3ee1d9dab8d
ToppCellParenchymal-NucSeq|Parenchymal / Cell types per location group and 10X technology with lineage, and cell group designations

NHSL1 NEDD4L TRIO RERE PDZD2

3.65e-051988451996373bdccc55aac347d349bd22f6aad6d0c668
ToppCellNeuron-Postmitotic-Excitatory_Neuron_-Newborn-35|World / Primary Cells by Cluster

DLGAP1 NEDD4L NRXN1 ZNF608 KMT2A

3.65e-05198845de5214a85fe017eb23d4aa8af624464f062ec57e
ToppCellBronchial-NucSeq-Epithelial-Epi_alveolar|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

NHSL1 FREM2 DLC1 NEDD4L PDZD2

3.74e-05199845725610310e5c5fd7120c0be9acb55bf152026ddd
ToppCellParenchymal-NucSeq-Epithelial-Epi_alveolar|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

NHSL1 FREM2 DLC1 NEDD4L PDZD2

3.74e-051998458587bd98de7767a575088afbea07a1feb4516b9b
ToppCellBronchial-10x5prime-Epithelial-Epi_airway_secretory-Secretory_Goblet|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

MUC16 ATP10B MUC5B FUT3 MUC20

3.74e-05199845ec1e110671e7725f752163c7241dbbf638dec2b2
ToppCellTracheal-10x5prime-Epithelial-Epi_airway_secretory|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

MUC16 ATP10B MUC5B FUT3 MUC20

3.74e-051998457223f853335492ca617dbec3e4b6872a8a463a45
ToppCellParenchymal-10x5prime-Epithelial-Epi_airway_secretory-Secretory_Goblet|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

MUC16 ATP10B MUC5B FUT3 MUC20

3.74e-051998453c3133d0aa65338a576634def13e7f0f5c573a10
ToppCellTracheal-10x5prime-Epithelial-Epi_airway_secretory-Secretory_Goblet|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

MUC16 ATP10B MUC5B FUT3 MUC20

3.74e-05199845e03bdc7cb825e287f41b834ec6061d23c1c03b04
ToppCellParenchymal-10x5prime-Epithelial-Epi_airway_secretory|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

MUC16 ATP10B MUC5B FUT3 MUC20

3.74e-05199845a706ad5cd5e0dc8d7e925a05e45b07d35963f294
ToppCellLPS_IL1RA-Endothelial-Endothelial-Gen_Cap|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

DLC1 ZNF608 TRIO KMT2A AFDN

3.83e-05200845dccec522ab0d7fff62ad6273b02aa9022dbbb8eb
ToppCellLPS_only-Endothelial|LPS_only / Treatment groups by lineage, cell group, cell type

DLC1 ZNF608 CARHSP1 AFDN LUZP1

3.83e-0520084581e76508c9050d533853d5fd2f3097b27613d836
ToppCellwk_08-11-Epithelial|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

NHSL1 FREM2 NEDD4L COL27A1 AGRN

3.83e-05200845445fc7995ffc440c6256a6aab0bbf33fb0fea028
ToppCellLPS_IL1RA-Endothelial-Endothelial-Activated_Alv_Cap|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

ZNF608 CARHSP1 MAP4 AFDN LUZP1

3.83e-0520084579e51afb57ca38aacebd0298e5e727b55c0cfff9
ToppCellSigmoid-Dendritic_cell-cycling_DCs|Dendritic_cell / Region, Cell class and subclass

RGL1 NCOR2 ATAD5 DLGAP5 POLA2

3.83e-05200845372fe9018481a4e9ac6ab3af43705a48238c4376
ToppCellLPS_only-Endothelial-Endothelial|LPS_only / Treatment groups by lineage, cell group, cell type

DLC1 ZNF608 CARHSP1 AFDN LUZP1

3.83e-052008454bb609a284d4e6066f17470a1736076aa4a1f84c
ToppCellPBMC-Mild-cDC_2|Mild / Compartment, Disease Groups and Clusters

FREM2 TREX1 DLGAP5 PDZD2

1.24e-04135844cb9d834f8301cf53f20e09c3f4cb6a148690196a
ToppCellsaliva-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD8_c01-LEF1|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

EVL TCERG1L MAP4 USP37

2.16e-041568448790b4b400695571fcf1ccb24c658b5e90854ff7
ToppCell343B-Lymphocytic-NK_cells-NK_cell_E|343B / Donor, Lineage, Cell class and subclass (all cells)

CCDC138 SLA2 SRCAP POLA2

2.22e-041578440362c04b7b0b5017964b3a73ee678ae53e7238d7
ToppCellHealthy/Control-Treg|World / Disease group and Cell class

EVL DLGAP1 CCR3 NCK2

2.44e-04161844457297cda5c9cee3bcc069fdecbbe24def027e5f
ToppCellLPS_only-Epithelial_airway-Club_cells-Airway|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

FREM2 ATP10B MUC5B MUC20

2.62e-04164844b1243b10591e1e15a94952e39ffbf382eae6aae8
ToppCellLPS_only-Epithelial_airway-Club_cells|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

FREM2 ATP10B MUC5B MUC20

2.62e-04164844c5b2001280a43da855017361a3f6071a0e492848
ToppCelldroplet-Marrow-BM-30m-Lymphocytic-plasma_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RGL1 FNDC1 DBNDD2 CCR3

2.62e-04164844758e85e2f5e7236b345e16c78344d5e0bf17d8dc
ToppCellLPS_only-Epithelial_airway|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

FREM2 ATP10B MUC5B MUC20

2.62e-0416484456e6934e6c7503a300d7be06762d45a1d6f1ae0f
ToppCell5'-Parenchyma_lung-Epithelial-Epithelial_transtional-secretory-tracheobronchial_goblet_cell|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

COL27A1 DAG1 CEP295 MUC5B

2.74e-0416684460060b03f2abfa3cc08107ab5a9f578e60e4ae16
ToppCell5'-Parenchyma_lung-Epithelial-Epithelial_transtional-secretory-tracheobronchial_goblet_cell-Goblet_(subsegmental)|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

COL27A1 DAG1 CEP295 MUC5B

2.74e-04166844ec9161d388db5a257b8d125c14f9dd911d5d5d4a
DrugTolfenamic acid [13710-19-5]; Up 200; 15.2uM; MCF7; HT_HG-U133A

NCOR2 NEDD4L MYO7A ATP10B RERE DMBT1 FUT3 PDZD2

8.31e-072008585454_UP
Drugrioprostil

MUC3B MUC12 FUT3 MUC3A

6.01e-0632854CID005311413
DrugAzlocillin sodium salt [37091-65-9]; Down 200; 8.2uM; HL60; HT_HG-U133A

RHBDF2 MAP4 SAFB2 RERE SRCAP AGRN MEF2D

8.52e-061958572727_DN
DrugEpicatechin-(-) [154-23-4]; Down 200; 13.8uM; MCF7; HT_HG-U133A

RGL1 DLC1 MAP4 MUC5B SRCAP NEK9 PDZD2

8.81e-061968574419_DN
DrugPiperacillin sodium salt [59703-84-3]; Down 200; 7.4uM; MCF7; HT_HG-U133A

RGL1 DLC1 MAP4 ATP10B NLGN1 RERE SRCAP

9.11e-061978573939_DN
DrugBetulinic acid [472-15-1]; Up 200; 8.8uM; MCF7; HT_HG-U133A

TRIO MYO7A SAFB2 KMT2A AFDN SRCAP MTSS2

9.11e-061978574181_UP
DrugMoxisylyte hydrochoride [964-52-3]; Down 200; 12.6uM; MCF7; HT_HG-U133A

ENDOD1 TRIO MAP4 ATAD5 SAFB2 RFX7 LUZP1

1.00e-052008577015_DN
DiseaseInhalant adrenergic use measurement

TRIO MUC16 ATP10B RERE MUC2

7.79e-0696835EFO_0009941
Diseasecholangiocarcinoma (is_marker_for)

MUC16 MUC5B MUC2 MUC3A

3.25e-0564834DOID:4947 (is_marker_for)
DiseaseNeurodevelopmental Disorders

DLGAP1 TRIO KMT2A SRCAP

1.40e-0493834C1535926
Diseaselithostathine-1-alpha measurement

DMBT1 FUT3

1.63e-047832EFO_0801083
Diseasesuberic acid measurement

TCERG1L PDZD2

1.63e-047832EFO_0010534
DiseaseRS-10-hydroxywarfarin to RS-warfarin ratio measurement

MUC3B NEDD4L NRXN1 MUC3A

2.68e-04110834EFO_0803335
Diseaseresponse to bronchodilator, FEV/FEC ratio

NCOR2 LRFN2 DLC1 NRXN1 MYO7A FAM227A ULK4 USP37 STPG2

3.03e-04766839EFO_0004713, GO_0097366
Diseaseglucagon-like peptide-1 measurement

ULK4 LMNB2

3.47e-0410832EFO_0008465
Diseasetauopathy (implicated_via_orthology)

EVL MAP4

3.47e-0410832DOID:680 (implicated_via_orthology)
Diseaseplasminogen activator inhibitor 1 measurement

MUC17 MUC12 RFX7

4.80e-0454833EFO_0004792
Diseasecystic fibrosis (is_marker_for)

CCR3 MUC5B MUC2

7.20e-0462833DOID:1485 (is_marker_for)
Diseaseradiation-induced disorder

DLC1 NRXN1 MUC12

9.03e-0467833EFO_0009565
Diseaseautism spectrum disorder (implicated_via_orthology)

LRFN2 NRXN1 NLGN1 MEF2D

9.07e-04152834DOID:0060041 (implicated_via_orthology)
Diseasegalectin-3 measurement

DLGAP5 FUT3

9.14e-0416832EFO_0008137
Diseaseautosomal dominant intellectual developmental disorder (is_implicated_in)

TRIO RFX7

1.03e-0317832DOID:0060307 (is_implicated_in)
Diseaserisk-taking behaviour

DLGAP1 LRFN2 NRXN1 ZNF608 RASGRF2 NLGN1 STPG2 MTSS2

1.39e-03764838EFO_0008579
Diseaseeotaxin measurement

CCR3 MEF2D PDZD2

1.51e-0380833EFO_0008122
Diseasemuscular dystrophy (implicated_via_orthology)

DAG1 LMNB2

1.59e-0321832DOID:9884 (implicated_via_orthology)
Diseasesensory peripheral neuropathy, remission

DLC1 KMT2A

1.90e-0323832EFO_0009785, MONDO_0002321
Diseasetemperament and character inventory

TCERG1L NRXN1

2.07e-0324832EFO_0004825
Diseaseinflammatory bowel disease (implicated_via_orthology)

MUC2 PDZD2

2.25e-0325832DOID:0050589 (implicated_via_orthology)
Diseasemigraine disorder, diastolic blood pressure

NCOR2 MEF2D

2.25e-0325832EFO_0006336, MONDO_0005277
Diseaseresponse to interferon

TCERG1L STPG2

2.25e-0325832EFO_0007859
Diseasepain

NRXN1 NLGN1 RERE MEF2D

2.30e-03196834EFO_0003843
DiseaseS-warfarin measurement

NHSL1 NCOR2 NLGN1

2.62e-0397833EFO_0803323
Diseasecaudate volume change measurement, age at assessment

DLC1 NRXN1

2.62e-0327832EFO_0008007, EFO_0021491
Diseaseoptic disc size measurement

DLC1 ABI3BP RERE PDZD2

2.71e-03205834EFO_0004832

Protein segments in the cluster

PeptideGeneStartEntry
LPTSKSTTRLDSDRV

AFDN

546

P55196
PKSTRRSGRISSTPT

ATAD5

591

Q96QE3
ATTKRPVILTTSDPT

ATAD5

1326

Q96QE3
VRREKTTSTPDCTPT

FAM227A

451

F5H4B4
PESPESLTSVSRTRR

CCDC86

16

Q9H6F5
SSRPRTTASVPRTTV

AGRN

1021

O00468
SPTASVTPTTRSRIR

SPECC1L

981

Q69YQ0
RTPRTTRSSVTSPDE

ANKIB1

306

Q9P2G1
LRSSSPPRTTTTVRT

DLGAP1

511

O14490
PPRTTTTVRTIQSST

DLGAP1

516

O14490
STTTEPRQRVTIKPS

ATP10B

596

O94823
ATATPSKTRTSTLLP

MUC5B

2841

Q9HC84
ATATPSKTRTSTLLP

MUC5B

3541

Q9HC84
RSVSVTSITSTVLPP

RGL1

626

Q9NZL6
TEELTSTSSRTSPPR

HECW2

396

Q9P2P5
RRTITSAAPTTSPIV

MUC16

2316

Q8WXI7
SKEPSISPEIRSTVR

MUC16

3211

Q8WXI7
TISRSIPKSSKTTRT

MUC16

4871

Q8WXI7
RAVTSTTLPTLTLSP

MUC16

10996

Q8WXI7
AVEPSTPTVLRSTST

NCOR2

1886

Q9Y618
TPTVLRSTSTSSPVR

NCOR2

1891

Q9Y618
TTLATSTARRGKPPT

NRXN1

321

P58400
TRSRTNRSSVKTPEP

MDC1

1146

Q14676
STDRPVTPKPTSRTT

MDC1

1296

Q14676
VTPKPTSRTTRSRTN

MDC1

1301

Q14676
PVTPKPTSRTTRSRT

MDC1

1341

Q14676
AKPSSTTPRLSRLAT

MAP4

911

P27816
TSTRKQPPSSRLSSL

KIAA1671

1561

Q9BY89
TKRPRSSTVTEAPIA

NEK9

326

Q8TD19
RRKTSARDASPTPST

NCK2

81

O43639
ISPARETRSFTKTSP

MUC20

86

Q8N307
ATPTTARTRPTTDVS

MUC20

641

Q8N307
RLKLSPSPSSRVTVS

LMNB2

401

Q03252
SSVPRRDSLSKTSTP

KIAA1109

4371

Q2LD37
SSVTVRSRKTDPPSA

FREM2

2041

Q5SZK8
STTTTTRRPTKKPRT

DAG1

441

Q14118
LETASPPTRIRTTTS

DAG1

471

Q14118
SSTRSKRSTLLPPEA

ENDOD1

306

O94919
SRGSLRPPSTKEETS

NHSL1

1051

Q5SYE7
RTPSTKPTVRRALSS

MTSS2

566

Q765P7
RPSTLTTFTTITLPT

MUC2

1261

Q02817
STTRTTERTPLPTGS

MUC3A

221

Q02505
SSPTRTILSSTPVLS

MUC3A

286

Q02505
TLVTTLPTTISRSTP

MUC3A

316

Q02505
STDIPTTSLRTLTPS

MUC3A

2481

Q02505
DTSIRTFVSPLTSPK

PDZD2

1976

O15018
SVEKPVSSILSRTPS

EVL

331

Q9UI08
RTSVIESPSTNRTTP

NRIP1

536

P48552
TTKVPSTDITFRPTR

NLGN1

666

Q8N2Q7
TTLATSTARRGKPPT

NRXN1

1326

Q9ULB1
TPSNSRTRKRPTSTS

HIDE1

201

A8MVS5
RTRKRPTSTSSSPET

HIDE1

206

A8MVS5
TREPRVLSATSATKS

EXOSC10

6

Q01780
KVALPTNTTSSRPRT

CCDC138

131

Q96M89
LPSEKLERTSSVSPS

CCR3

331

P51677
LPVPTSDRTTSRTSS

DBNDD2

201

Q9BQY9
PRPTTATTRRTTTTR

FNDC1

1466

Q4ZHG4
VPRTVSSTTARKPVT

DLGAP5

216

Q15398
TTSSSKKPIPTLART

COL27A1

446

Q8IZC6
PEPSSRRTQSSLTVS

LUZP1

986

Q86V48
TSSLRSEPPKTRRTS

FAM47A

501

Q5JRC9
SEPPKTRRTSSLRSE

FAM47A

506

Q5JRC9
EVRVRSPTRSPSVKT

KMT2A

156

Q03164
LSIEKPRTASTETPR

CEP295

2456

Q9C0D2
SRSTPRPDTLSTITL

DMBT1

706

Q9UGM3
TTASTRPSVSAPTVR

SBNO1

126

A3KN83
TPTVPRISRTAITTA

FAM126B

306

Q8IXS8
ISIKSEPVSPSRERS

MEF2D

436

Q14814
TEGRTPLTSITVRTT

MUC17

1686

Q685J3
PLTSITVRTTPVASS

MUC17

1691

Q685J3
VTTIRISITSERSTP

MUC17

3861

Q685J3
SSTTRTTERTPLPTG

MUC3B

221

Q9H195
SSRQDTTPTRPTLLI

FUT3

51

P21217
QKPSVRRISTTSPRS

RTN4IP1

26

Q8WWV3
SRRKSLPSPSLSSSV

SLA2

6

Q9H6Q3
TSSPVRARKLSLTSP

RASGRF2

736

O14827
TPVVSSTPRLTTSER

MRPL35

51

Q9NZE8
RPRPVVTTTTSTTVV

SHISA5

141

Q8N114
TKSVTRPTRSSAEIT

TRGV5

26

A0A0B4J1U4
RIKTRTASTPVNTPS

RERE

461

Q9P2R6
STPETPLTKRSVSTR

POLA2

126

Q14181
NTVTTVTISTSPPKR

SRCAP

2991

Q6ZRS2
TTATLTPQAPRERTT

SSC5D

696

A1L4H1
SAVSTPSPVTRTRSL

DLC1

751

Q96QB1
TSRARSVSISVPSTP

RITA1

241

Q96K30
STPPSVTSKSRVSRL

SLC39A6

221

Q13433
SPLPTRRTRTFSATV

CARHSP1

41

Q9Y2V2
KIPLRTSPVSDTRTE

TCERG1L

276

Q5VWI1
ISRSPTLTRSVDVPS

STPG2

76

Q8N412
SSARPRPSTDVKSQT

ZNF556

351

Q9HAH1
TIRSPTTVLFTSSPI

RFX7

346

Q2KHR2
PVISVKTTSRSKERS

SAFB2

581

Q14151
STTPTRKITESPRAS

TP53BP1

1646

Q12888
KSFRTPTIRSITPLS

PKHD1L1

141

Q86WI1
TPSRKRQASESSSRP

UCK2

246

Q9BZX2
SLTRSPPTASQTRTL

nan

6

A8MUU9
ASLTRTPPTASLTRT

nan

271

A8MUU9
RTIPSLTSTSTPLRS

USP37

181

Q86T82
FTTVIPSKVSSPARR

VXN

16

Q8TAG6
KRVRTNSRSTPTTPQ

ZNF608

521

Q9ULD9
RKRRSTPLTSSTLPS

ZNF212

11

Q9UDV6
RPTTVTPETVPRSTK

ABI3BP

326

Q7Z7G0
VSSVSSSRLQSRKPP

RHBDF2

11

Q6PJF5
TASARTKPRPSAVTT

TREX1

236

Q9NSU2
SSRLLVRPTSSETPS

TRIO

1891

O75962
LSSRPTPRTSTAVEV

ULK4

361

Q96C45
FPRSTTTSVRREEPT

MUC12

3956

Q9UKN1
TSRTAPPKSRLSDIT

LRFN2

386

Q9ULH4
TSRTLITRGETVSTP

MYO7A

371

Q13402
IRRPRSLSSPTVTLS

NEDD4L

441

Q96PU5