Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionnucleoside-triphosphatase regulator activity

RASGRP4 MYCBP2 ARHGAP36 RABGAP1 ASAP1 RABGAP1L RASA4B DOCK6 ARHGEF28 PRR5 ARFGEF2 ARHGEF18 ALS2 DEPDC1 MADD PLEKHG4B RASA4 EIF5 NPRL3 SMCR8

7.92e-0850718920GO:0060589
GeneOntologyMolecularFunctionGTPase regulator activity

RASGRP4 MYCBP2 ARHGAP36 RABGAP1 ASAP1 RABGAP1L RASA4B DOCK6 ARHGEF28 PRR5 ARFGEF2 ARHGEF18 ALS2 DEPDC1 MADD PLEKHG4B RASA4 EIF5 NPRL3 SMCR8

7.92e-0850718920GO:0030695
GeneOntologyMolecularFunctiontestosterone 6-beta-hydroxylase activity

CYP3A7 CYP3A4 CYP3A5

8.23e-0651893GO:0050649
GeneOntologyMolecularFunctionGTPase activator activity

ARHGAP36 RABGAP1 ASAP1 RABGAP1L RASA4B PRR5 ALS2 DEPDC1 RASA4 EIF5 NPRL3 SMCR8

1.48e-0527918912GO:0005096
GeneOntologyMolecularFunctionenzyme regulator activity

RASGRP4 MYCBP2 ARHGAP36 RABGAP1 BIRC6 ASAP1 MGAT5 RABGAP1L PDP2 RASA4B C4A C4B DOCK6 ARHGEF28 PRR5 ARFGEF2 ARHGEF18 ALS2 DEPDC1 TRIM23 MADD ITIH5 PLEKHG4B FRY RASA4 EIF5 NPRL3 CCAR2 SMCR8 PPP1R16A

2.71e-05141818930GO:0030234
GeneOntologyMolecularFunctionestrogen 2-hydroxylase activity

CYP3A7 CYP3A4 CYP3A5

4.51e-0581893GO:0101021
GeneOntologyMolecularFunctionguanyl-nucleotide exchange factor activity

RASGRP4 MYCBP2 DOCK6 ARHGEF28 ARFGEF2 ARHGEF18 ALS2 MADD PLEKHG4B SMCR8

7.32e-0523118910GO:0005085
GeneOntologyMolecularFunctionestrogen 16-alpha-hydroxylase activity

CYP3A7 CYP3A4 CYP3A5

1.30e-04111893GO:0101020
GeneOntologyMolecularFunctiondystroglycan binding

MAP2 CLASP2 CLASP1

1.72e-04121893GO:0002162
GeneOntologyMolecularFunctiontransketolase activity

TKTL2 TKT

2.66e-0431892GO:0004802
GeneOntologyMolecularFunctionretinoic acid 4-hydroxylase activity

CYP3A7 CYP3A4 CYP3A5

2.81e-04141893GO:0008401
GeneOntologyMolecularFunctionactin filament binding

MYH2 XIRP1 CTNNAL1 CLASP2 SPTBN5 SYNE1 FHOD3 MYH14 FHOD1

3.23e-042271899GO:0051015
GeneOntologyMolecularFunctionoxygen binding

CYP3A7 CYP3A4 CYP3A5 HBQ1

4.02e-04371894GO:0019825
GeneOntologyMolecularFunctiontestosterone 16-alpha-hydroxylase activity

CYP3A4 CYP3A5

5.28e-0441892GO:0008390
GeneOntologyMolecularFunctionprotein-membrane adaptor activity

SYNE2 AKAP6 SYNE1 ATG2B

8.55e-04451894GO:0043495
GeneOntologyMolecularFunctiontransketolase or transaldolase activity

TKTL2 TKT

8.75e-0451892GO:0016744
GeneOntologyMolecularFunctionC-X3-C chemokine binding

ITGAV ITGB3

8.75e-0451892GO:0019960
GeneOntologyMolecularFunctionvitamin D 23-hydroxylase activity

CYP3A4 CYP3A5

8.75e-0451892GO:0062179
GeneOntologyMolecularFunction1-alpha,25-dihydroxyvitamin D3 23-hydroxylase activity

CYP3A4 CYP3A5

8.75e-0451892GO:0062181
GeneOntologyMolecularFunctioncytoskeleton-nuclear membrane anchor activity

SYNE2 SYNE1

8.75e-0451892GO:0140444
GeneOntologyMolecularFunctionneuregulin binding

ITGAV ITGB3

1.30e-0361892GO:0038132
GeneOntologyMolecularFunctionvitamin D3 25-hydroxylase activity

CYP3A4 CYP3A5

1.30e-0361892GO:0030343
GeneOntologyMolecularFunctionvitamin D 24-hydroxylase activity

CYP3A4 CYP3A5

1.30e-0361892GO:0070576
GeneOntologyMolecularFunctionopsonin binding

ITGAV C4A C4B

1.65e-03251893GO:0001846
GeneOntologyMolecularFunctionprotein kinase A regulatory subunit binding

AKAP6 ARFGEF2 AKAP9

1.65e-03251893GO:0034237
GeneOntologyMolecularFunctionvitamin D 25-hydroxylase activity

CYP3A4 CYP3A5

1.81e-0371892GO:0070643
GeneOntologyMolecularFunctionactin binding

MYH2 XIRP1 CTNNAL1 MAP2 CLASP2 SPTBN5 HOOK1 SYNE2 SYNE1 FHOD3 MYH14 FHOD1

2.10e-0347918912GO:0003779
GeneOntologyMolecularFunctionprotein kinase A binding

AKAP4 AKAP6 ARFGEF2 AKAP9

2.21e-03581894GO:0051018
GeneOntologyMolecularFunctiondynein light intermediate chain binding

HOOK1 DNAH10 DNAH1

2.30e-03281893GO:0051959
GeneOntologyMolecularFunctionthiamine pyrophosphate binding

TKTL2 TKT

2.40e-0381892GO:0030976
GeneOntologyMolecularFunctionstructural constituent of presynaptic active zone

ERC1 PCLO

2.40e-0381892GO:0098882
GeneOntologyMolecularFunctionoxidoreductase activity, acting on CH or CH2 groups, quinone or similar compound as acceptor

CYP3A4 CYP3A5

2.40e-0381892GO:0033695
GeneOntologyMolecularFunctioncaffeine oxidase activity

CYP3A4 CYP3A5

2.40e-0381892GO:0034875
GeneOntologyBiologicalProcesscentrosome localization

SYNE2 PKHD1 SYNE1 AKAP9 FHOD1

1.55e-05351885GO:0051642
GeneOntologyBiologicalProcessmicrotubule organizing center localization

SYNE2 PKHD1 SYNE1 AKAP9 FHOD1

1.79e-05361885GO:0061842
GeneOntologyBiologicalProcessregulation of organelle organization

MAP2 MYCBP2 MYOC ERC1 MCIDAS LRSAM1 CLASP2 RABGAP1 ITGB3 ASAP1 AXIN2 SPTBN5 NCAPG ALMS1 SYNE2 CLASP1 RB1 SYNE1 ARHGEF18 FHOD3 CEP192 AKAP9 LMNA NPTXR FHOD1 PDE4DIP SMCR8 EP300

3.42e-05134218828GO:0033043
GeneOntologyBiologicalProcessorganelle assembly

XIRP1 MCIDAS LRSAM1 CLASP2 RABGAP1 ASAP1 AKAP4 TEKT2 MDN1 ALMS1 SYNE2 PKHD1 CLASP1 SYNE1 ATG2B FHOD3 CEP192 CFAP43 DNAH1 NPTXR EIF5 UHRF1 SMCR8 EP300 PCNT

4.11e-05113818825GO:0070925
GeneOntologyBiologicalProcessregulation of small GTPase mediated signal transduction

RASGRP4 LZTR1 MYOC ITGAV RASA4B ARHGEF28 ARFGEF2 ARHGEF18 ALS2 MADD PLEKHG4B RASA4

5.79e-0533318812GO:0051056
GeneOntologyBiologicalProcesslipid hydroxylation

CYP3A7 CYP3A4 CYP3A5

6.01e-0591883GO:0002933
GeneOntologyBiologicalProcessactomyosin structure organization

XIRP1 MYOC CLASP2 ALMS1 CLASP1 ARHGEF18 FHOD3 MYH14 FHOD1 EP300

7.13e-0523918810GO:0031032
GeneOntologyBiologicalProcessregulation of cellular component biogenesis

MAP2 MYCBP2 MYOC MCIDAS LRSAM1 CLASP2 RABGAP1 ASAP1 SPTBN5 ALMS1 SYNE2 CUX2 CLASP1 RB1 SYNE1 SLITRK4 ARHGEF18 FHOD3 CEP192 AKAP9 NPTXR FHOD1 PDE4DIP SMCR8 EP300

8.31e-05118918825GO:0044087
GeneOntologyBiologicalProcessmicrotubule cytoskeleton organization

MAP2 MCIDAS CLASP2 TEKT2 ALMS1 HOOK1 SYNE2 PKHD1 NLRP5 CLASP1 CEP192 CFAP43 DNAH1 AKAP9 LMNA PDE4DIP UHRF1 PCNT

1.09e-0472018818GO:0000226
GeneOntologyBiologicalProcesswound healing, spreading of epidermal cells

CLASP2 ITGAV ITGB3 CLASP1

1.15e-04281884GO:0035313
GeneOntologyBiologicalProcesssmall GTPase-mediated signal transduction

RASGRP4 CTNNAL1 LZTR1 MYOC ITGAV RASA4B DOCK6 ARHGEF28 ARFGEF2 ARHGEF18 ALS2 MADD PLEKHG4B RASA4 RFXANK

1.29e-0453818815GO:0007264
GeneOntologyBiologicalProcessregulation of actomyosin structure organization

MYOC CLASP2 ALMS1 CLASP1 ARHGEF18 FHOD1 EP300

1.30e-041221887GO:0110020
GeneOntologyBiologicalProcessoxidative demethylation

CYP3A7 CYP3A4 CYP3A5

1.54e-04121883GO:0070989
GeneOntologyBiologicalProcessmicrotubule nucleation

CLASP2 CLASP1 CEP192 AKAP9 PDE4DIP

1.70e-04571885GO:0007020
GeneOntologyBiologicalProcessregulation of supramolecular fiber organization

MAP2 MYOC CLASP2 SPTBN5 ALMS1 CLASP1 RB1 ARHGEF18 FHOD3 AKAP9 FHOD1 PDE4DIP EP300

2.00e-0443818813GO:1902903
GeneOntologyBiologicalProcessnuclear migration

SYNE2 SYNE1 LMNA FHOD1

2.50e-04341884GO:0007097
GeneOntologyBiologicalProcessregulation of organelle assembly

MCIDAS LRSAM1 RABGAP1 ASAP1 ALMS1 SYNE2 SYNE1 CEP192 NPTXR SMCR8

2.59e-0428018810GO:1902115
GeneOntologyBiologicalProcessmicrotubule-based process

CFAP251 MAP2 MCIDAS CLASP2 AKAP4 TEKT2 ALMS1 HOOK1 SYNE2 PKHD1 NLRP5 DNAH10 CLASP1 CEP192 CFAP43 MADD DNAH1 AKAP9 LMNA PDE4DIP UHRF1 PCNT

2.67e-04105818822GO:0007017
GeneOntologyCellularComponentcell cortex region

ERC1 CLASP2 SPTBN5 NLRP5 CLASP1 PCLO

2.79e-06451866GO:0099738
GeneOntologyCellularComponentcytoplasmic region

CFAP251 MAP2 ERC1 CLASP2 SPTBN5 TEKT2 NLRP5 DNAH10 CLASP1 PCLO ARFGEF2 CFAP43 MADD DNAH1

4.47e-0636018614GO:0099568
GeneOntologyCellularComponentcentrosome

ERC1 CCDC18 CLASP2 RABGAP1 BIRC6 AXIN2 ALMS1 HOOK1 PKHD1 NLRC5 CLASP1 ARFGEF2 ALS2 CEP192 ECPAS FRY EYS AKAP9 PDE4DIP LRRCC1 PCNT

5.38e-0677018621GO:0005813
GeneOntologyCellularComponentcortical microtubule cytoskeleton

CLASP2 CLASP1 PDE4DIP

6.84e-0651863GO:0030981
GeneOntologyCellularComponentmicrotubule organizing center

ERC1 CCDC18 CLASP2 RABGAP1 BIRC6 AXIN2 TEKT2 ALMS1 HOOK1 PKHD1 NLRC5 CLASP1 ARFGEF2 ALS2 CEP192 ECPAS FRY EYS AKAP9 PDE4DIP LRRCC1 PCNT

2.43e-0591918622GO:0005815
GeneOntologyCellularComponentcytoplasmic microtubule plus-end

CLASP2 PDE4DIP

7.87e-0521862GO:1904511
GeneOntologyCellularComponentcortical microtubule plus-end

CLASP2 PDE4DIP

7.87e-0521862GO:1903754
GeneOntologyCellularComponentdesmosome

XIRP1 KAZN DSC1 PKP3

1.05e-04281864GO:0030057
GeneOntologyCellularComponentcortical cytoskeleton

MYH2 ERC1 CLASP2 SPTBN5 CLASP1 PCLO PDE4DIP

1.58e-041291867GO:0030863
GeneOntologyCellularComponentalphav-beta3 integrin-PKCalpha complex

ITGAV ITGB3

2.35e-0431862GO:0035866
GeneOntologyCellularComponentalphav-beta3 integrin-HMGB1 complex

ITGAV ITGB3

2.35e-0431862GO:0035868
GeneOntologyCellularComponentintegrin alphav-beta3 complex

ITGAV ITGB3

2.35e-0431862GO:0034683
GeneOntologyCellularComponentcortical microtubule

CLASP2 PDE4DIP

2.35e-0431862GO:0055028
GeneOntologyCellularComponentmotile cilium

CFAP251 PRAMEF1 PRAMEF2 AKAP4 TEKT2 DNAH10 CFAP43 PRAMEF13 DNAH1 AKAP9 PCNT

3.53e-0435518611GO:0031514
GeneOntologyCellularComponentcilium

CFAP251 MYOC ERC1 PRAMEF1 PRAMEF2 SPTBN5 AKAP4 TEKT2 ALMS1 PKHD1 DNAH10 ARFGEF2 CFAP43 PPEF2 PRAMEF13 DNAH1 EYS AKAP9 PCNT

4.29e-0489818619GO:0005929
GeneOntologyCellularComponentalphav-beta3 integrin-IGF-1-IGF1R complex

ITGAV ITGB3

4.67e-0441862GO:0035867
GeneOntologyCellularComponentfilopodium membrane

ITGAV ITGB3 SYNE2

8.19e-04211863GO:0031527
GeneOntologyCellularComponentcell-cell junction

MYH2 XIRP1 ITGB3 KCNJ11 KAZN AKAP6 DSC1 FRMPD2 PLEKHG4B FRMD4A PKP3 FHOD1 PALS2 SYMPK

8.59e-0459118614GO:0005911
GeneOntologyCellularComponentlamellipodium membrane

ITGAV ITGB3 SYNE2

9.42e-04221863GO:0031258
GeneOntologyCellularComponentanchoring junction

MYH2 XIRP1 CLASP2 ITGA1 ITGAV ITGB3 KCNJ11 SYNE2 KAZN AKAP6 DSC1 CLASP1 FRMPD2 PLEKHG4B FRMD4A PKP3 FHOD1 PALS2 SYMPK

1.16e-0397618619GO:0070161
GeneOntologyCellularComponentbasal cortex

CLASP2 CLASP1

1.61e-0371862GO:0045180
GeneOntologyCellularComponentdendritic branch

MAP2 AKAP9

1.61e-0371862GO:0044307
GeneOntologyCellularComponentmicrotubule plus-end

CLASP2 CLASP1 PDE4DIP

1.93e-03281863GO:0035371
GeneOntologyCellularComponentpericentriolar material

CEP192 AKAP9 PCNT

1.93e-03281863GO:0000242
GeneOntologyCellularComponentsymbiont cell surface

C4A C4B

2.13e-0381862GO:0106139
GeneOntologyCellularComponentcytoskeleton of presynaptic active zone

ERC1 PCLO

2.13e-0381862GO:0048788
GeneOntologyCellularComponentplasma membrane bounded cell projection cytoplasm

CFAP251 MAP2 SPTBN5 TEKT2 DNAH10 ARFGEF2 CFAP43 MADD DNAH1

2.20e-033171869GO:0032838
GeneOntologyCellularComponentaxoneme

CFAP251 SPTBN5 TEKT2 DNAH10 ARFGEF2 CFAP43 DNAH1

2.59e-032071867GO:0005930
GeneOntologyCellularComponentciliary plasm

CFAP251 SPTBN5 TEKT2 DNAH10 ARFGEF2 CFAP43 DNAH1

2.66e-032081867GO:0097014
GeneOntologyCellularComponentother organism part

C4A C4B

2.72e-0391862GO:0044217
GeneOntologyCellularComponentintegrin complex

ITGA1 ITGAV ITGB3

2.84e-03321863GO:0008305
GeneOntologyCellularComponentintercalated disc

XIRP1 KCNJ11 AKAP6 FHOD1

3.17e-03681864GO:0014704
GeneOntologyCellularComponentapical cortex

SPTBN5 NLRP5

3.38e-03101862GO:0045179
GeneOntologyCellularComponentinner dynein arm

DNAH10 DNAH1

3.38e-03101862GO:0036156
GeneOntologyCellularComponentnuclear membrane protein complex

SYNE2 SYNE1

4.11e-03111862GO:0106083
GeneOntologyCellularComponentnuclear membrane microtubule tethering complex

SYNE2 SYNE1

4.11e-03111862GO:0106094
GeneOntologyCellularComponentmicrotubule organizing center attachment site

SYNE2 SYNE1

4.11e-03111862GO:0034992
GeneOntologyCellularComponentmeiotic nuclear membrane microtubule tethering complex

SYNE2 SYNE1

4.11e-03111862GO:0034993
DomainATPase_dyneun-rel_AAA

VWA8 MDN1 DNAH10 DNAH1

9.79e-06141914IPR011704
DomainAAA_5

VWA8 MDN1 DNAH10 DNAH1

9.79e-06141914PF07728
DomainCyt_P450_E_grp-II

CYP3A7 CYP3A4 CYP3A5

1.04e-0551913IPR002402
DomainCyt_P450_E_CYP3A

CYP3A7 CYP3A4 CYP3A5

2.06e-0561913IPR008072
Domain-

LRSAM1 TLR7 PRAMEF1 PRAMEF2 FBXL3 LRRC37A NLRC5 NLRP5 LRRC8C SLITRK4 PRAMEF13 LRRCC1 LGR6

2.76e-05321191133.80.10.10
DomainL_dom-like

LRSAM1 TLR7 PRAMEF1 PRAMEF2 FBXL3 LRRC37A NLRC5 NLRP5 LRRC8C SLITRK4 PRAMEF13 LRRCC1 LGR6

3.45e-0532819113IPR032675
DomainPACT_coil_coil

AKAP9 PCNT

1.04e-0421912PF10495
DomainPACT_domain

AKAP9 PCNT

1.04e-0421912IPR019528
DomainHEAT

CLASP2 NCAPG CLASP1 ECPAS SYMPK

1.27e-04481915PF02985
DomainSPEC

SPTBN5 SYNE2 AKAP6 SYNE1

3.05e-04321914SM00150
DomainSpectrin/alpha-actinin

SPTBN5 SYNE2 AKAP6 SYNE1

3.05e-04321914IPR018159
DomainTransketolase_N

TKTL2 TKT

3.10e-0431912PF00456
DomainTransketolase_N

TKTL2 TKT

3.10e-0431912IPR005474
DomainTRANSKETOLASE_1

TKTL2 TKT

3.10e-0431912PS00801
DomainTRANSKETOLASE_2

TKTL2 TKT

3.10e-0431912PS00802
Domain-

RASA4B RASA4

3.10e-04319124.10.1130.10
DomainHEAT

CLASP2 NCAPG CLASP1 ECPAS SYMPK

3.13e-04581915IPR000357
DomainKASH

SYNE2 SYNE1

6.16e-0441912IPR012315
DomainKASH

SYNE2 SYNE1

6.16e-0441912PS51049
DomainCLASP_N

CLASP2 CLASP1

6.16e-0441912PF12348
DomainCLASP_N_dom

CLASP2 CLASP1

6.16e-0441912IPR024395
DomainKASH

SYNE2 SYNE1

6.16e-0441912SM01249
DomainKASH

SYNE2 SYNE1

6.16e-0441912PF10541
Domain-

RABGAP1 ASAP1 SPTBN5 RABGAP1L RASA4B ARHGEF28 FRMPD2 ARHGEF18 ALS2 PLEKHG4B FRMD4A RASA4

7.19e-04391191122.30.29.30
DomainARM-type_fold

USP34 CLASP2 NCAPG CLASP1 ARFGEF2 FHOD3 ECPAS PKP3 FHOD1 EIF5 SYMPK

7.60e-0433919111IPR016024
DomainPRAME_family

PRAMEF1 PRAMEF2 PRAMEF13

9.04e-04191913IPR026271
DomainDZF

ZFR2 ZFR

1.02e-0351912SM00572
DomainTransketolase_C

TKTL2 TKT

1.02e-0351912IPR033248
DomainTransketolase_fam

TKTL2 TKT

1.02e-0351912IPR033247
DomainAnaphylatoxin_comp_syst

C4A C4B

1.02e-0351912IPR018081
DomainAnaphylatoxn_comp_syst_dom

C4A C4B

1.02e-0351912IPR001840
DomainDZF_dom

ZFR2 ZFR

1.02e-0351912IPR006561
DomainTransketo_C/PFOR_II

TKTL2 TKT

1.02e-0351912IPR009014
DomainTransketolase_C

TKTL2 TKT

1.02e-0351912PF02780
Domain-

TKTL2 TKT

1.02e-03519123.40.50.920
DomainDZF

ZFR2 ZFR

1.02e-0351912PF07528
DomainDZF

ZFR2 ZFR

1.02e-0351912PS51703
DomainLRR

LRSAM1 TLR7 LRRC37A NLRC5 LRRC8C SLITRK4 LRRCC1 LGR6

1.11e-032011918PS51450
DomainCadherin

FREM1 FREM2 DSC1 PCDHGB6 PCDHGA11 PCDHGA5

1.35e-031181916IPR002126
DomainPH_dom-like

RABGAP1 ASAP1 SPTBN5 RABGAP1L RASA4B ARHGEF28 FRMPD2 ARHGEF18 ALS2 PLEKHG4B FRMD4A RASA4

1.50e-0342619112IPR011993
DomainKinesin-like

RABGAP1 RABGAP1L

1.52e-0361912IPR022164
DomainDUF3694

RABGAP1 RABGAP1L

1.52e-0361912PF12473
DomainVWFA

VWA8 ITGA1 ITGB3 MDN1 ITIH5

1.53e-03821915PS50234
DomainSpectrin

SPTBN5 SYNE2 SYNE1

1.60e-03231913PF00435
DomainACTININ_2

SPTBN5 SYNE2 SYNE1

1.60e-03231913PS00020
DomainACTININ_1

SPTBN5 SYNE2 SYNE1

1.60e-03231913PS00019
DomainActinin_actin-bd_CS

SPTBN5 SYNE2 SYNE1

1.60e-03231913IPR001589
DomainVWA

VWA8 ITGA1 ITGB3 MDN1 ITIH5

1.71e-03841915SM00327
DomainARM-like

CLASP2 NCAPG CLASP1 ARFGEF2 FHOD3 ECPAS PKP3 FHOD1 SYMPK

1.89e-032701919IPR011989
DomainLRR_1

LRSAM1 TLR7 LRRC37A NLRC5 LRRC8C SLITRK4 LRRCC1 LGR6

1.91e-032191918PF00560
DomainLeu-rich_rpt

LRSAM1 TLR7 LRRC37A NLRC5 NLRP5 LRRC8C SLITRK4 LRRCC1 LGR6

1.94e-032711919IPR001611
DomainIntegrin_dom

ITGA1 ITGAV ITGB3

2.05e-03251913IPR032695
Domain-

CLASP2 NCAPG CLASP1 ARFGEF2 ECPAS PKP3 FHOD1 SYMPK

2.08e-0322219181.25.10.10
DomainANATO

C4A C4B

2.11e-0371912SM00104
DomainANAPHYLATOXIN_2

C4A C4B

2.11e-0371912PS01178
DomainANAPHYLATOXIN_1

C4A C4B

2.11e-0371912PS01177
DomainANATO

C4A C4B

2.11e-0371912PF01821
DomainAnaphylatoxin/fibulin

C4A C4B

2.11e-0371912IPR000020
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

GPBP1 MAP2 MYCBP2 RIMKLA ERC1 BACH1 CCDC18 CLASP2 MDN1 ALMS1 HOOK1 RABGAP1L SYNE2 DOCK6 ARHGEF28 CLASP1 PRR5 ALS2 CEP192 MADD AKAP9 N4BP2 EIF5 CEP170B CDK3

1.70e-118611932536931259
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

UBE4B ERC1 SPEG ASAP1 ZFR2 RABGAP1L CLASP1 SYNE1 BEND3 ALS2 CEP192 NUP214 MADD AKAP9 PDE4DIP CCAR2 CEP170B PCNT

1.71e-114071931812693553
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

USP34 NDOR1 LZTR1 UBE4B MYCBP2 VWA8 SPEG CLASP2 PIGG BIRC6 MDN1 KCNJ11 C19orf44 NLRC5 DOCK6 ARFGEF2 CEP192 NUP214 CFAP43 MADD ZNF503 NPRL3 EP300 CEP170B PCNT PPP1R16A SYMPK

1.20e-1011051932735748872
Pubmed

A human skeletal muscle interactome centered on proteins involved in muscular dystrophies: LGMD interactome.

KANSL1L ZBTB38 MYCBP2 PEG10 CLASP2 BIRC6 ASAP1 ALMS1 SYNE2 ANKRD28 AKAP6 SYNE1 GLIS3 AKAP9 LMNA MYH14 TKT PDE4DIP

4.35e-104971931823414517
Pubmed

Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.

USP34 MYCBP2 ERC1 BIRC6 ALMS1 SYNE2 ANKRD28 AKAP6 CUX2 SYNE1 ALS2 PCNT

5.64e-092251931212168954
Pubmed

Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.

USP34 MYCBP2 TRIML2 ERC1 RABGAP1 BIRC6 ALMS1 ANKRD28 ATG2B BEND3 ZDBF2 NUP214 ECPAS N4BP2 PCNT

1.48e-084181931534709266
Pubmed

EB1-binding-myomegalin protein complex promotes centrosomal microtubules functions.

CLASP2 BIRC6 AKAP9 LMNA TKT PKP3 PDE4DIP

6.18e-0863193729162697
Pubmed

The P450 oxidoreductase genotype is associated with CYP3A activity in vivo as measured by the midazolam phenotyping test.

CYP3A7 CYP3A4 CYP3A5

1.68e-073193319801957
Pubmed

Cytochrome P450 3A gene variation, steroid hormone serum levels and prostate cancer--The Rotterdam Study.

CYP3A7 CYP3A4 CYP3A5

1.68e-073193320621111
Pubmed

Cytochrome P450 3As gene expression and testosterone 6 beta-hydroxylase activity in human fetal membranes and placenta at full term.

CYP3A7 CYP3A4 CYP3A5

1.68e-073193320118548
Pubmed

Metabolic pathways of inhaled glucocorticoids by the CYP3A enzymes.

CYP3A7 CYP3A4 CYP3A5

1.68e-073193323143891
Pubmed

Development of template systems for ligand interactions of CYP3A5 and CYP3A7 and their distinctions from CYP3A4 template.

CYP3A7 CYP3A4 CYP3A5

1.68e-073193333866277
Pubmed

Contribution of three CYP3A isoforms to metabolism of R- and S-warfarin.

CYP3A7 CYP3A4 CYP3A5

1.68e-073193320615193
Pubmed

Comparison of steroid hormone hydroxylation mediated by cytochrome P450 3A subfamilies.

CYP3A7 CYP3A4 CYP3A5

1.68e-073193332001245
Pubmed

Lamins and nesprin-1 mediate inside-out mechanical coupling in muscle cell precursors through FHOD1.

SYNE1 LMNA FHOD1

1.68e-073193328455503
Pubmed

CYP3A Polymorphism and Chronic Mercury Intoxication.

CYP3A7 CYP3A4 CYP3A5

1.68e-073193332146629
Pubmed

Structures of FHOD1-Nesprin1/2 complexes reveal alternate binding modes for the FH3 domain of formins.

SYNE2 SYNE1 FHOD1

1.68e-073193333472039
Pubmed

Differences in CYP3A41G genotype distribution and haplotypes of CYP3A4, CYP3A5 and CYP3A7 in 3 Chinese populations.

CYP3A7 CYP3A4 CYP3A5

1.68e-073193317582393
Pubmed

CYP3A7, CYP3A4, and CYP3A5 genetic polymorphisms in recipients rather than donors influence tacrolimus concentrations in the early stages after liver transplantation.

CYP3A7 CYP3A4 CYP3A5

1.68e-073193334688813
Pubmed

An antibody-based proximity labeling map reveals mechanisms of SARS-CoV-2 inhibition of antiviral immunity.

USP34 MYCBP2 CLASP2 BIRC6 ALMS1 ANKRD28 ABCC1 LMF1 CLASP1 ARHGEF18 ZDBF2 NUP214 MADD ZNF503 N4BP2 CCAR2 ZMYM1 RPAP2

1.68e-077331931834672954
Pubmed

Network organization of the human autophagy system.

MYH2 ERC1 RABGAP1 FREM1 RABGAP1L DSC1 ATG2B ECPAS LMNA TKT EIF5 CCAR2 SMCR8 CEP170B

1.82e-074371931420562859
Pubmed

Comparative host-coronavirus protein interaction networks reveal pan-viral disease mechanisms.

MYCBP2 VWA8 ERC1 PIGG FANCD2 MDN1 HOOK1 DOCK6 ABCC1 NUP214 ECPAS ZNF503 AKAP9 MYH14 PDE4DIP ZFR ZMYM1 PCNT

2.54e-077541931833060197
Pubmed

Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.

CTNNAL1 LZTR1 MYCBP2 ERC1 CCDC18 CLASP2 BIRC6 ASAP1 FANCD2 NCAPG SYNE2 PDP2 ANKRD28 ABCC1 CEP192 PPEF2 MADD AKAP9 CCAR2 PCNT SYMPK

4.47e-0710491932127880917
Pubmed

Mouse screen reveals multiple new genes underlying mouse and human hearing loss.

RASGRP4 CTNNAL1 LZTR1 TRIM25 CYP3A4 CYP3A5 CCDC18 PRAMEF1 PRAMEF2 MDN1 BPGM KAZN KLRB1 SLITRK4 ASTE1 UBA2 ARHGEF18 SETD4 PRAMEF13 AKAP9 MYH14 SYMPK RPAP2

4.75e-0712421932330973865
Pubmed

SUN1 interacts with nuclear lamin A and cytoplasmic nesprins to provide a physical connection between the nuclear lamina and the cytoskeleton.

SYNE2 SYNE1 LMNA

6.70e-074193316648470
Pubmed

Allele and genotype frequencies of CYP3A4, CYP3A5, CYP3A7, and GSTP1 gene polymorphisms among mainland Tibetan, Mongolian, Uyghur, and Han Chinese populations.

CYP3A7 CYP3A4 CYP3A5

6.70e-074193334689350
Pubmed

LINC complexes mediate the positioning of cone photoreceptor nuclei in mouse retina.

SYNE2 SYNE1 LMNA

6.70e-074193323071752
Pubmed

CYP3A7, CYP3A5, CYP3A4, and ABCB1 genetic polymorphisms, cyclosporine concentration, and dose requirement in transplant recipients.

CYP3A7 CYP3A4 CYP3A5

6.70e-074193318978522
Pubmed

Alternative complement pathway component Factor D contributes to efficient clearance of tissue debris following acute CCl₄-induced injury.

CFD C4A C4B

6.70e-074193325467802
Pubmed

FBXO22 promotes leukemogenesis by targeting BACH1 in MLL-rearranged acute myeloid leukemia.

MAP2 SPEG LRSAM1 BACH1 CLASP2 MDN1 ANKRD28 C4A C4B CLASP1 SLITRK4 NUP214 ECPAS ZFR

8.47e-074971931436774506
Pubmed

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.

UBE4B MAP2 MYCBP2 CLASP2 RABGAP1 ZC4H2 SLC10A7 NLRC5 DOCK6 LMF1 FRMPD2 PRR5 ARHGEF18 CEP192 ECPAS DNAH1 PLEKHG4B MYH14 PKP3 PALS2 METTL15 EP300 CEP170B PCNT RPAP2

8.78e-0714891932528611215
Pubmed

Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability.

USP34 ERC1 LRSAM1 RABGAP1 ALMS1 HOOK1 CLASP1 RB1 UBA2 ZDBF2 CEP192 N4BP2 CEP170B PCNT RPAP2

1.17e-065881931538580884
Pubmed

Prediction of the coding sequences of unidentified human genes. XVIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.

TRPM3 BEND3 ALS2 ZDBF2 CEP192 KIAA1586 ZNF529

1.61e-06101193710997877
Pubmed

Neuron-specific protein network mapping of autism risk genes identifies shared biological mechanisms and disease-relevant pathologies.

KCNH7 MAP2 MYCBP2 VWA8 ERC1 BACH1 RABGAP1 BIRC6 ASAP1 RABGAP1L ANKRD28 IARS1 PCLO ATG2B ZDBF2 MADD FRMD4A SFXN5 LMNA PDE4DIP CEP170B

1.66e-0611391932136417873
Pubmed

Cytochrome P450 isoforms are differently up-regulated in aflatoxin B₁-exposed human lymphocytes and monocytes.

CYP3A7 CYP3A4 CYP3A5

1.67e-065193324168324
Pubmed

Genomic organization of the human CYP3A locus: identification of a new, inducible CYP3A gene.

CYP3A7 CYP3A4 CYP3A5

1.67e-065193311266076
Pubmed

Identification of human cytochrome P450s involved in the formation of all-trans-retinoic acid principal metabolites.

CYP3A7 CYP3A4 CYP3A5

1.67e-065193311093772
Pubmed

Human cytochrome P450 3A7 has a distinct high catalytic activity for the 16alpha-hydroxylation of estrone but not 17beta-estradiol.

CYP3A7 CYP3A4 CYP3A5

1.67e-065193314559847
Pubmed

Essential role of mannose-binding lectin-associated serine protease-1 in activation of the complement factor D.

CFD C4A C4B

1.67e-065193320038603
Pubmed

Interactomes of Glycogen Synthase Kinase-3 Isoforms.

ERC1 CLASP2 ALMS1 ANKRD28 CLASP1 ATG2B ZDBF2 CEP192 CEP170B

2.81e-06209193936779422
Pubmed

Pramel7 mediates ground-state pluripotency through proteasomal-epigenetic combined pathways.

PRAMEF1 PRAMEF2 PRAMEF13 UHRF1

3.34e-0619193428604677
Pubmed

Proximity biotinylation and affinity purification are complementary approaches for the interactome mapping of chromatin-associated protein complexes.

TRIM25 MYCBP2 ERC1 CCDC18 NCAPG ALMS1 RBM27 RB1 ATG2B ZNF503 MYH14 UHRF1 EP300 PCNT RPAP2

3.63e-066451931525281560
Pubmed

Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.

USP34 MYCBP2 BIRC6 MDN1 SYNE2 ANKRD28 BEND3 NUP214 ECPAS LMNA MYH14 CCAR2 ZFR PCNT SYMPK

4.20e-066531931522586326
Pubmed

VCP phosphorylation-dependent interaction partners prevent apoptosis in Helicobacter pylori-infected gastric epithelial cells.

TRIM25 RABGAP1 MDN1 HOOK1 CLASP1 ARFGEF2 ALS2 LMNA FHOD1 ZFR

5.34e-062881931023383273
Pubmed

Proteome-scale mapping of binding sites in the unstructured regions of the human proteome.

TRIM25 ITGB3 ASAP1 CUX2 GLIS3 ARHGEF18 NUP214 PLEKHG4B LMNA ZFR ZMYM1 PCNT

5.76e-064301931235044719
Pubmed

MKRN2 Physically Interacts with GLE1 to Regulate mRNA Export and Zebrafish Retinal Development.

TRIM25 MYCBP2 ERC1 ASAP1 SYNE2 RB1 IARS1 LMNA HES4 EP300 RPAP2

5.78e-063581931132460013
Pubmed

The human cytochrome P450 3A locus. Gene evolution by capture of downstream exons.

CYP3A7 CYP3A4 CYP3A5

5.79e-067193311137287
Pubmed

Association between ABCC2 polymorphism and lopinavir accumulation in peripheral blood mononuclear cells of HIV-infected patients.

CYP3A7 CYP3A4 CYP3A5

5.79e-067193319842932
Pubmed

Protective immune responses against West Nile virus are primed by distinct complement activation pathways.

CFD C4A C4B

5.79e-067193316651386
Pubmed

A function for cyclin D1 in DNA repair uncovered by protein interactome analyses in human cancers.

FANCD2 RB1 LMNA FHOD1 CCAR2 CDK3 SYMPK

6.67e-06125193721654808
Pubmed

Estrogen-dependent uterine secretion of osteopontin activates blastocyst adhesion competence.

ESR2 ITGA1 ITGAV ITGB3

7.49e-0623193423152823
Pubmed

Large-scale characterization of HeLa cell nuclear phosphoproteins.

UBE4B MYCBP2 BACH1 FANCD2 MDN1 CLASP1 ARFGEF2 UBA2 NUP214 ECPAS LMNA TKT PKP3 FHOD1 CCAR2 SYMPK

7.54e-067741931615302935
Pubmed

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

MYCBP2 ERC1 CLASP2 MDN1 HOOK1 SYNE2 ANKRD28 CLASP1 SYNE1 ARHGEF18 FRY AKAP9 N4BP2 PDE4DIP CCAR2 ZFR CEP170B PCNT

7.94e-069631931828671696
Pubmed

Human Immunodeficiency Virus Type 1 Vpr Mediates Degradation of APC1, a Scaffolding Component of the Anaphase-Promoting Complex/Cyclosome.

MYCBP2 TRIML2 ERC1 PEG10 ALMS1 ANKRD28 ATG2B NUP214 SYMPK

9.20e-06242193934011540
Pubmed

Protein kinase A, Ca2+/calmodulin-dependent kinase II, and calcineurin regulate the intracellular trafficking of myopodin between the Z-disc and the nucleus of cardiac myocytes.

AKAP4 AKAP6 PDE4DIP

9.23e-068193317923693
Pubmed

Essential role of complement mannose-binding lectin-associated serine proteases-1/3 in the murine collagen antibody-induced model of inflammatory arthritis.

CFD C4A C4B

9.23e-068193320870940
Pubmed

A phenotype-genotype approach to predicting CYP450 and P-glycoprotein drug interactions with the mixed inhibitor/inducer tipranavir/ritonavir.

CYP3A7 CYP3A4 CYP3A5

9.23e-068193320147896
Pubmed

Knockout and knockin of the beta1 exon D define distinct roles for integrin splice variants in heart function and embryonic development.

ITGA1 ITGAV ITGB3

9.23e-06819339553049
Pubmed

A High-Density Human Mitochondrial Proximity Interaction Network.

MYCBP2 VWA8 RABGAP1 PEX11B BIRC6 FANCD2 SPTBN5 MDN1 ALMS1 SYNE2 SYNE1 PCLO ATG2B BEND3 ZDBF2 GFM2 AKAP9 PTAR1 CCAR2 ZFR SMCR8 METTL15 PCNT

1.05e-0514961932332877691
Pubmed

Kelch Domain of Gigaxonin Interacts with Intermediate Filament Proteins Affected in Giant Axonal Neuropathy.

SPTBN5 ALMS1 SYNE2 DNAH10 CLASP1 SYNE1 MYH14 PCNT

1.06e-05187193826460568
Pubmed

PROTAC-mediated degradation reveals a non-catalytic function of AURORA-A kinase.

MYCBP2 RBM12B BIRC6 NCAPG MDN1 RBM27 CEP192 FRY RFXANK

1.08e-05247193932989298
Pubmed

Characterization of integrin engagement during defined human embryonic stem cell culture.

ITGA1 ITGAV ITGB3

1.38e-059193319933311
Pubmed

Nuclear monomeric integrin αv in cancer cells is a coactivator regulated by thyroid hormone.

ITGAV ITGB3 EP300

1.38e-059193323640055
Pubmed

Surviving mousepox infection requires the complement system.

CFD C4A C4B

1.38e-059193319112490
Pubmed

Integrin recognition of different cell-binding fragments of laminin (P1, E3, E8) and evidence that alpha 6 beta 1 but not alpha 6 beta 4 functions as a major receptor for fragment E8.

ITGA1 ITGAV ITGB3

1.38e-05919331693624
Pubmed

Identification of genes regulated by an interaction between alphavbeta3 integrin and vitronectin in murine decidua.

ITGAV ITGB3 RB1

1.38e-059193318255021
Pubmed

Differences in gene expression between mouse and human for dynamically regulated genes in early embryo.

PRAMEF1 PRAMEF2 NLRP5 PRAMEF13

1.70e-0528193425089626
Pubmed

E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.

BIRC6 FREM2 MDN1 TRPM3 ZFR2 PKHD1 KAZN LRRC8C RB1 IARS1 PCLO ECPAS FRY LMNA SYMPK

1.73e-057361931529676528
Pubmed

Novel asymmetrically localizing components of human centrosomes identified by complementary proteomics methods.

ALMS1 CLASP1 CEP192 AKAP9 PDE4DIP LRRCC1 PCNT

1.84e-05146193721399614
Pubmed

mTOR Inhibition via Rapamycin Treatment Partially Reverts the Deficit in Energy Metabolism Caused by FH Loss in RPE Cells.

VWA8 LRSAM1 SYNE2 RB1 FHOD1 METTL15

1.86e-0598193634943047
Pubmed

Nesprin 1α2 is essential for mouse postnatal viability and nuclear positioning in skeletal muscle.

SYNE2 SYNE1 LMNA

1.96e-0510193328533284
Pubmed

Mechanisms of mannose-binding lectin-associated serine proteases-1/3 activation of the alternative pathway of complement.

CFD C4A C4B

1.96e-0510193321943708
Pubmed

Irinotecan pathway genotype analysis to predict pharmacokinetics.

CYP3A4 CYP3A5 ABCC1

1.96e-0510193312960109
Pubmed

CEP192 interacts physically and functionally with the K63-deubiquitinase CYLD to promote mitotic spindle assembly.

RBM12B ALMS1 CEP192

1.96e-0510193322895009
Pubmed

Characterization of the oxidative metabolites of 17beta-estradiol and estrone formed by 15 selectively expressed human cytochrome p450 isoforms.

CYP3A7 CYP3A4 CYP3A5

1.96e-0510193312865317
Pubmed

Disrupted in Schizophrenia 1 Interactome: evidence for the close connectivity of risk genes and a potential synaptic basis for schizophrenia.

RABGAP1 HOOK1 AKAP6 SYNE1 FRMD4A AKAP9 PDE4DIP

2.29e-05151193717043677
Pubmed

CHK2-BRCA1 tumor-suppressor axis restrains oncogenic Aurora-A kinase to ensure proper mitotic microtubule assembly.

TRIM25 ERC1 ALMS1 IARS1 ARFGEF2 NUP214 ECPAS LMNA MYH14 TKT CCAR2 ZFR

2.29e-054941931226831064
Pubmed

Cell cycle regulation of the activity and subcellular localization of Plk1, a human protein kinase implicated in mitotic spindle function.

ALMS1 CLASP1 CEP192 AKAP9 PCNT

2.31e-056119357790358
Pubmed

Cullin 1 (CUL1) Promotes Primary Ciliogenesis through the Induction of Ubiquitin-Proteasome-Dependent Dvl2 Degradation.

ERC1 FREM1 SYNE1 NUP214 AKAP9 PDE4DIP EP300

2.38e-05152193734299191
Pubmed

Prediction of the coding sequences of unidentified human genes. XVI. The complete sequences of 150 new cDNA clones from brain which code for large proteins in vitro.

SPEG RBM27 PDP2 DOCK6 DNAH1 FRMD4A N4BP2

2.49e-05153193710718198
Pubmed

Prediction of the coding sequences of unidentified human genes. VII. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro.

MDN1 ALMS1 ANKRD28 AKAP6 ECPAS MADD

2.61e-0510419369205841
Pubmed

CTDP1 regulates breast cancer survival and DNA repair through BRCT-specific interactions with FANCI.

UBE4B MDN1 ABCC1 ARFGEF2 FHOD1 EP300

2.61e-05104193631240132
Pubmed

Prediction of the coding sequences of unidentified human genes. IX. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro.

USP34 VWA8 LRRC37A PCLO ARHGEF18 RASA4

2.76e-0510519369628581
Pubmed

Copy number analysis of complement C4A, C4B and C4A silencing mutation by real-time quantitative polymerase chain reaction.

C4A C4B

3.06e-052193222737222
Pubmed

Deficiency of C4 from donor or recipient mouse fails to prevent renal allograft rejection.

C4A C4B

3.06e-052193216565498
Pubmed

Complete deficiencies of complement C4A and C4B including 2-bp insertion in codon 1213 are genetic risk factors of systemic lupus erythematosus in Thai populations.

C4A C4B

3.06e-052193215998580
Pubmed

Effects of Genetic Polymorphism in CYP3A4 and CYP3A5 Genes on Tacrolimus Dose Among Kidney Transplant Recipients.

CYP3A4 CYP3A5

3.06e-052193227225724
Pubmed

Cardiac αVβ3 integrin expression following acute myocardial infarction in humans.

ITGAV ITGB3

3.06e-052193227927700
Pubmed

Crystal structure of the extracellular segment of integrin alpha Vbeta3.

ITGAV ITGB3

3.06e-052193211546839
Pubmed

Intracranial microenvironment reveals independent opposing functions of host alphaVbeta3 expression on glioma growth and angiogenesis.

ITGAV ITGB3

3.06e-052193217028191
Pubmed

High lung-metastatic variant of human osteosarcoma cells, selected by passage of lung metastasis in nude mice, is associated with increased expression of α(v)β(3) integrin.

ITGAV ITGB3

3.06e-052193224023288
Pubmed

Overexpression and Activation of αvβ3 Integrin Differentially Affects TGFβ2 Signaling in Human Trabecular Meshwork Cells.

ITGAV ITGB3

3.06e-052193234440692
Pubmed

Digging Deeper into CYP3A Testosterone Metabolism: Kinetic, Regioselectivity, and Stereoselectivity Differences between CYP3A4/5 and CYP3A7.

CYP3A7 CYP3A4

3.06e-052193228986474
Pubmed

High-throughput analysis of the C4 polymorphism by a combination of MLPA and isotype-specific ELISA's.

C4A C4B

3.06e-052193219062096
Pubmed

Mammalian CLASP1 and CLASP2 cooperate to ensure mitotic fidelity by regulating spindle and kinetochore function.

CLASP2 CLASP1

3.06e-052193216914514
Pubmed

Expression profiling reveals genes associated with transendothelial migration of tumor cells: a functional role for alphavbeta3 integrin.

ITGAV ITGB3

3.06e-052193217621633
Pubmed

αvβ3-integrin is a major sensor and activator of innate immunity to herpes simplex virus-1.

ITGAV ITGB3

3.06e-052193223150579
Pubmed

Alpha(v)beta(3) integrin engagement enhances cell invasiveness in human multiple myeloma.

ITGAV ITGB3

3.06e-052193212161360
Pubmed

Integrin alphaVbeta3 Binds to the RGD motif of glycoprotein B of Kaposi's sarcoma-associated herpesvirus and functions as an RGD-dependent entry receptor.

ITGAV ITGB3

3.06e-052193218045938
Pubmed

Regulation of macrophage foam cell formation by alphaVbeta3 integrin: potential role in human atherosclerosis.

ITGAV ITGB3

3.06e-052193215215180
InteractionGOLGA1 interactions

LZTR1 TRIM25 ERC1 CCDC18 BIRC6 CFD ALMS1 ANKRD28 ATG2B ZDBF2 CEP192 SMCR8 CEP170B PCNT

2.05e-0918318914int:GOLGA1
InteractionPFN1 interactions

TRIM25 ERC1 ESR2 RABGAP1 BIRC6 FANCD2 CFD ALMS1 RABGAP1L SYNE2 ANKRD28 PCLO CEP192 TRIM23 AKAP9 TKT N4BP2 FHOD1 PCNT RPAP2

7.28e-0850918920int:PFN1
InteractionZYX interactions

TRIM25 ARHGAP36 ESR2 FANCD2 CFD ALMS1 KLHL6 ALS2 CEP192 PLEKHG4B N4BP2 ZFR SMCR8 EP300 CEP170B PCNT

9.12e-0832918916int:ZYX
InteractionKDM1A interactions

USP34 TRIM25 MYCBP2 TRIML2 ERC1 ESR2 RABGAP1 BIRC6 FANCD2 NCAPG ALMS1 RABGAP1L ANKRD28 RB1 ATG2B UBA2 BEND3 ZDBF2 NUP214 ECPAS AKAP9 N4BP2 PDE4DIP UHRF1 EP300 PCNT SYMPK

2.24e-0794118927int:KDM1A
InteractionMYOM1 interactions

FANCD2 ANKRD28 SYNE1 TRIM23 PDE4DIP PPP1R16A

3.81e-07311896int:MYOM1
InteractionYWHAZ interactions

TRIM25 PDE7A GPBP1 MAP2 MYCBP2 ERC1 SPEG ESR2 CCDC18 CLASP2 FANCD2 CFD RBM27 SYNE2 ANKRD28 ARHGEF28 DSC1 CLASP1 PRR5 ARHGEF18 ALS2 CEP192 MADD AKAP9 LMNA TKT FHOD1 EIF5 CCAR2 EP300 CEP170B PCNT

6.56e-07131918932int:YWHAZ
InteractionYWHAH interactions

GPBP1 MAP2 MYCBP2 RIMKLA ERC1 SPEG ESR2 CCDC18 CLASP2 FANCD2 ALMS1 HOOK1 RABGAP1L SYNE2 DOCK6 ARHGEF28 CLASP1 PRR5 ALS2 CEP192 MADD FRMD4A AKAP9 EIF5 CCAR2 CEP170B CDK3 PCNT

1.48e-06110218928int:YWHAH
InteractionNDC80 interactions

WDR64 ERC1 CCDC18 BIRC6 ALMS1 RBM27 SYNE2 C19orf44 RB1 CEP192 AKAP9 LRRCC1 CEP170B PCNT

1.56e-0631218914int:NDC80
InteractionSFN interactions

TRIM25 GPBP1 MAP2 MYCBP2 RIMKLA ESR2 BACH1 CCDC18 CLASP2 FANCD2 ALMS1 RABGAP1L ARHGEF28 CLASP1 PRR5 CEP192 AKAP9 LMNA TKT PKP3 CEP170B

2.33e-0669218921int:SFN
InteractionPHF21A interactions

USP34 MYCBP2 ERC1 RABGAP1 BIRC6 ALMS1 RABGAP1L ANKRD28 ATG2B BEND3 ZDBF2 NUP214 ECPAS PCNT

4.67e-0634318914int:PHF21A
InteractionHDAC1 interactions

MYH2 MYCBP2 ERC1 ESR2 BACH1 RABGAP1 BIRC6 FANCD2 CFD NCAPG ALMS1 SYNE2 ANKRD28 RB1 ATG2B BEND3 ZDBF2 NUP214 ECPAS AKAP9 MYH14 SKOR1 UHRF1 CCAR2 EP300 PCNT SYMPK

5.07e-06110818927int:HDAC1
InteractionVCL interactions

TRIM25 ESR2 BIRC6 ITGB3 ASAP1 FANCD2 ALMS1 CLASP1 CEP192 N4BP2 EIF5 SMCR8 RPAP2

6.48e-0630518913int:VCL
InteractionDCTN2 interactions

ERC1 CLASP2 NCAPG ALMS1 C19orf44 ANKRD28 DNAH10 CLASP1 UBA2 CEP192 AKAP9 N4BP2 EP300 PCNT

7.15e-0635618914int:DCTN2
InteractionCDK5RAP2 interactions

CCDC18 BIRC6 ALMS1 CEP192 AKAP9 LMNA TKT PKP3 PDE4DIP PCNT

1.28e-0519018910int:CDK5RAP2
InteractionPLEC interactions

MAP2 ESR2 ITGB3 FANCD2 CFD NCAPG HOOK1 SYNE2 KAZN TKT N4BP2 PDE4DIP CCAR2 PGBD4 PCNT

1.40e-0543018915int:PLEC
InteractionPXN interactions

ERC1 ESR2 CCDC18 ITGAV BIRC6 ITGB3 ASAP1 ALMS1 HOOK1 CEP192 AKAP9 N4BP2 PCNT

1.71e-0533418913int:PXN
InteractionTOP3B interactions

USP34 NDOR1 LZTR1 TRIM25 UBE4B MYCBP2 VWA8 SPEG CLASP2 PIGG BIRC6 AXIN2 MDN1 KCNJ11 C19orf44 NLRC5 DOCK6 IARS1 ARFGEF2 CEP192 NUP214 CFAP43 MADD ZNF503 NPRL3 ZFR EP300 CEP170B PCNT PPP1R16A SYMPK

1.74e-05147018931int:TOP3B
InteractionDTNBP1 interactions

TRIML2 ASAP1 ALMS1 AKAP6 COPZ1 SYNE1 AKNAD1 ARFGEF2 PCNT

2.28e-051621899int:DTNBP1
InteractionGSK3A interactions

TRIM25 MAP2 ERC1 LRSAM1 CLASP2 AXIN2 MDN1 ALMS1 ANKRD28 CLASP1 ATG2B ZDBF2 CEP192 AKAP9 CEP170B

3.38e-0546418915int:GSK3A
InteractionYWHAG interactions

GPBP1 MAP2 MYCBP2 RIMKLA ERC1 SPEG ESR2 CCDC18 CLASP2 FANCD2 CFD MDN1 ALMS1 RABGAP1L SYNE2 ARHGEF28 CLASP1 PRR5 ALS2 CEP192 PPEF2 FRMD4A AKAP9 LMNA N4BP2 EIF5 CEP170B

4.20e-05124818927int:YWHAG
InteractionRANGAP1 interactions

TRIM25 MYCBP2 ARHGAP36 ESR2 CLASP2 AXIN2 FANCD2 CLASP1 NUP214 ECPAS LMNA EP300

4.32e-0531418912int:RANGAP1
InteractionGLRX interactions

TRIM25 CCDC18 TKTL2 WDR53 TKT

6.20e-05451895int:GLRX
InteractionANAPC2 interactions

ERC1 ESR2 CCDC18 BIRC6 ALMS1 RB1 CEP192 N4BP2 EP300 PCNT

7.56e-0523418910int:ANAPC2
InteractionDUSP16 interactions

UBE4B ALMS1 HOOK1 C19orf44 ATG2B CEP192 N4BP2 NPRL3 SMCR8 PCNT

8.40e-0523718910int:DUSP16
InteractionNXT2 interactions

VWA8 NXF3 NUP214 TRIM23 PTAR1

8.49e-05481895int:NXT2
InteractionANGPTL3 interactions

ITGAV BIRC6 ITGB3

9.28e-05101893int:ANGPTL3
InteractionCEP170P1 interactions

SYNE2 IARS1 ZNF503 AKAP9 CCAR2 CEP170B SYMPK

9.54e-051131897int:CEP170P1
InteractionAGPS interactions

VWA8 ERC1 CFD ALMS1 ANKRD28 CEP192 N4BP2 EP300 PCNT

1.01e-041961899int:AGPS
InteractionDYNC1LI1 interactions

TRIM25 ESR2 CLASP2 HOOK1 DOCK6 CLASP1 NUP214 TKT ZFR PCNT

1.14e-0424618910int:DYNC1LI1
InteractionGAN interactions

ESR2 SPTBN5 ALMS1 SYNE2 CTU1 DNAH10 CLASP1 SYNE1 MYH14 PCNT

1.44e-0425318910int:GAN
InteractionDENND5A interactions

TRIM25 BIRC6 BEND3 MADD

1.48e-04291894int:DENND5A
InteractionMCM4 interactions

ZBTB38 TRIM25 ITGB3 FANCD2 CFD HOOK1 COPZ1 RB1 ATG2B LMNA EP300

1.55e-0430618911int:MCM4
InteractionCYTH1 interactions

BACH1 FANCD2 TRIM23 FRMD4A PCNT

1.64e-04551895int:CYTH1
InteractionCYP3A5 interactions

CYP3A7 CYP3A4 CYP3A5

1.68e-04121893int:CYP3A5
InteractionTHY1 interactions

UBE4B ITGAV ITGB3 FANCD2 ZFR

1.78e-04561895int:THY1
InteractionFBXO22 interactions

TRIM25 MAP2 SPEG LRSAM1 BACH1 CLASP2 MDN1 ANKRD28 C4A C4B CLASP1 SLITRK4 NUP214 ECPAS ZFR

1.83e-0454018915int:FBXO22
InteractionAMOT interactions

ERC1 CCDC18 BIRC6 AXIN2 ALMS1 ANKRD28 CEP192 N4BP2 PALS2 EP300 PCNT

1.83e-0431218911int:AMOT
Cytoband1p36.21

PRAMEF1 PRAMEF2 KAZN PRAMEF13

1.49e-046319341p36.21
GeneFamilyZinc fingers MYND-type|A-kinase anchoring proteins

MAP2 AKAP4 AKAP6 ARFGEF2 AKAP9

1.52e-06291255396
GeneFamilyCytochrome P450 family 3

CYP3A7 CYP3A4 CYP3A5

1.76e-05812531002
GeneFamilySpectrin repeat containing nuclear envelope family

SYNE2 SYNE1

2.82e-04412521252
GeneFamilyPRAME family

PRAMEF1 PRAMEF2 PRAMEF13

5.87e-04241253686
GeneFamilyC3 and PZP like, alpha-2-macroglobulin domain containing

C4A C4B

1.65e-03912521234
GeneFamilyComplement system|Sushi domain containing

CFD C4A C4B

1.95e-03361253492
GeneFamilyPleckstrin homology domain containing|SH2 domain containing|C2 and RasGAP domain containing

RASA4B RASA4

2.06e-03101252830
GeneFamilyBasic leucine zipper proteins|BTB domain containing

ZBTB38 LZTR1 BACH1 KLHL6 ZBTB25

2.39e-031341255861
CoexpressionGSE11386_NAIVE_VS_MEMORY_BCELL_DN

TRIM25 MYCBP2 RIMKLA ASAP1 MGAT5 MDN1 RABGAP1L NLRC5 SYNE1 AKAP9

2.89e-0715819310M372
CoexpressionLAKE_ADULT_KIDNEY_C3_PROXIMAL_TUBULE_EPITHELIAL_CELLS_S1_S2

KANSL1L ZBTB38 PDE7A VWA8 TRPM3 RABGAP1L SYNE2 PKHD1 ARHGEF28 PCLO FHOD3

8.09e-0722119311M39222
CoexpressionMURARO_PANCREAS_BETA_CELL

USP34 ZBTB38 MAP2 MYCBP2 RIMKLA SPEG CLASP2 ASAP1 HOOK1 KCNJ11 SYNE2 PCLO GLIS3 ARFGEF2 ECPAS TRIM23 MADD MYH14 RASA4 PTAR1 PDE4DIP PALS2

2.05e-0694619322M39169
CoexpressionLAKE_ADULT_KIDNEY_C4_PROXIMAL_TUBULE_EPITHELIAL_CELLS_S2

KANSL1L ZBTB38 PDE7A VWA8 ITGAV SYNE2 PKHD1 GLIS3 FHOD3

6.65e-061761939M39223
CoexpressionGSE21670_UNTREATED_VS_TGFB_IL6_TREATED_CD4_TCELL_UP

USP34 UBE4B CCDC18 NCAPG SYNE2 DEPDC1 CEP192 UHRF1 ZMYM1

1.46e-051941939M7467
CoexpressionGSE7831_1H_VS_4H_CPG_STIM_PDC_DN

PDE7A CCDC18 TLR7 BIRC6 MGAT5 FHOD3 NPTXR RASA4 METTL15

1.78e-051991939M6961
CoexpressionGOBERT_OLIGODENDROCYTE_DIFFERENTIATION_DN

NDOR1 SPEG PIGG PRAMEF1 PRAMEF2 FBXL3 ASAP1 ALMS1 RABGAP1L ANKRD28 C4A C4B KAZN LRRC8C LMF1 SYNE1 GLIS3 FHOD3 CEP192 ECPAS PRAMEF13 ZFR

3.03e-05112419322MM1070
CoexpressionGSE7568_CTRL_VS_3H_TGFB_TREATED_MACROPHAGES_WITH_IL4_AND_DEXAMETHASONE_DN

MGAT5 RBM27 ANKRD28 ATG2B NUP214 ECPAS PTAR1 ZFR

3.49e-051671938M361
CoexpressionLAKE_ADULT_KIDNEY_C15_CONNECTING_TUBULE

KANSL1L ITGAV TRPM3 RABGAP1L PKHD1 KAZN GLIS3 FHOD3

4.13e-051711938M39234
CoexpressionMANNO_MIDBRAIN_NEUROTYPES_HNBGABA

ZBTB38 MAP2 MYCBP2 ERC1 HOOK1 LRRC8C PCLO SLITRK4 FHOD3 FRMD4A FRY AKAP9 NPTXR RASA4 PDE4DIP NPAS4

6.98e-0570319316M39070
CoexpressionAtlasFacebaseRNAseq_e8.5_Hind Brain Neural Epithelium_top-relative-expression-ranked_2500_k-means-cluster#3

PDE7A GPBP1 CCDC18 BIRC6 NCAPG ALMS1 HOOK1 RBM27 ANKRD28 ABCC1 IARS1 PCLO FHOD3 ZDBF2 CEP192 ECPAS N4BP2 EIF5 PALS2 PCNT

5.41e-0853218720Facebase_RNAseq_e8.5_Hind Brain Neural Epithelium_2500_K3
CoexpressionAtlasfacebase_RNAseq_e10.5_Emin_MedNas_2500_K1

PDE7A SWT1 RIMKLA ERC1 FANCD2 TMEM62 ALMS1 HOOK1 SYNE2 CUX2 CLASP1 SLITRK4 ASTE1 PRR5 FHOD3 ZDBF2 DEPDC1 CEP192 FAM83C MADD FRMD4A SFXN5 AKAP9 MYH14 LRRCC1 ZMYM1

2.22e-06106018726facebase_RNAseq_e10.5_Emin_MedNas_2500_K1
CoexpressionAtlasFacebaseRNAseq_e10.5_Mandibular Arch_top-relative-expression-ranked_500_k-means-cluster#5

CCDC18 NCAPG ALMS1 ARFGEF2 FHOD3 ZDBF2 CEP192 AKAP9 LRRCC1

4.16e-051861879Facebase_RNAseq_e10.5_Mandibular Arch_500_K5
CoexpressionAtlasfacebase_RNAseq_e10.5_Emin_LatNas_2500_K3

PDE7A SWT1 TLR7 FANCD2 NCAPG MDN1 ALMS1 HOOK1 RBM27 SYNE2 ANKRD28 CLASP1 RB1 ARFGEF2 BEND3 FHOD3 ZDBF2 DEPDC1 CEP192 FRMD4A SFXN5 AKAP9 MYH14 ZBTB25 EIF5 LRRCC1

4.38e-05125718726facebase_RNAseq_e10.5_Emin_LatNas_2500_K3
CoexpressionAtlasfacebase_RNAseq_e10.5_Emin_MedNas_2500

PDE7A MAP2 SWT1 RIMKLA ERC1 FANCD2 TMEM62 ALMS1 HOOK1 SYNE2 PKHD1 CUX2 CLASP1 SLITRK4 ASTE1 PRR5 FHOD3 ZDBF2 DEPDC1 CEP192 FAM83C MADD FRMD4A SFXN5 AKAP9 MYH14 LRRCC1 ZMYM1

4.68e-05141418728facebase_RNAseq_e10.5_Emin_MedNas_2500
CoexpressionAtlasFacebaseRNAseq_e8.5_Floor Plate_top-relative-expression-ranked_1000

CTNNAL1 GPBP1 MAP2 BIRC6 WDR53 FREM2 TEKT2 ALMS1 HOOK1 RB1 PCLO GLIS3 FHOD3 ZDBF2 CEP192 GFM2 ZNF503 AKAP9 MYH14 FHOD1 LRRCC1 PALS2

6.72e-0599418722Facebase_RNAseq_e8.5_Floor Plate_1000
CoexpressionAtlasfacebase_RNAseq_e10.5_Emin_LatNas_2500

PDE7A MAP2 SWT1 RIMKLA TLR7 FANCD2 NCAPG MDN1 ALMS1 HOOK1 RBM27 SYNE2 ANKRD28 CLASP1 RB1 ARFGEF2 BEND3 FHOD3 ZDBF2 DEPDC1 CEP192 FRMD4A SFXN5 AKAP9 MYH14 ZBTB25 EIF5 LRRCC1

8.05e-05145918728facebase_RNAseq_e10.5_Emin_LatNas_2500
CoexpressionAtlasFacebaseRNAseq_e8.5_Floor Plate_top-relative-expression-ranked_1000_k-means-cluster#1

ALMS1 HOOK1 RB1 PCLO FHOD3 ZDBF2 CEP192 AKAP9 LRRCC1 PALS2

1.05e-0425918710Facebase_RNAseq_e8.5_Floor Plate_1000_K1
CoexpressionAtlasDevelopingKidney_e15.5_Medullary collecting duct_emap-28063_k-means-cluster#4_top-relative-expression-ranked_1000

MYCBP2 VWA8 RABGAP1 BIRC6 ARHGEF28 ARFGEF2 NUP214 ECPAS AKAP9 EIF5

1.11e-0426118710gudmap_developingKidney_e15.5_Medullary collecting duct_1000_k4
CoexpressionAtlasFacebaseRNAseq_e10.5_Neural Epithelium Overlying Lateral Eminence_top-relative-expression-ranked_1000

MAP2 CCDC18 TEKT2 MDN1 ALMS1 HOOK1 RBM27 FIBIN ZFR2 RABGAP1L SYNE2 ANKRD28 DNAH10 PCLO FHOD3 ZDBF2 MADD AKAP9 EIF5 LRRCC1 PCNT

1.62e-0498318721Facebase_RNAseq_e10.5_Neural Epithelium Overlying Lateral Eminence_1000
CoexpressionAtlasdev lower uro neuro_e15.5_BladdPelvicGanglion_Sox10_k-means-cluster#4_top-relative-expression-ranked_1000

MAP2 ARHGAP36 CLASP2 ZC4H2 CUX2 ARHGEF28 PCLO ZDBF2 FRMD4A FRY

1.86e-0427818710gudmap_dev lower uro neuro_e15.5_BladdPelvicGanglion_Sox10_k4_1000
CoexpressionAtlasFacebaseRNAseq_e10.5_Neural Epithelium Overlying Lateral Eminence_top-relative-expression-ranked_2500_k-means-cluster#5

VWA8 RBM12B BPGM ALMS1 HOOK1 RBM27 SYNE2 ANKRD28 PCLO SLITRK4 FHOD3 ZDBF2 MADD AKAP9 EIF5 PCNT

2.31e-0465418716Facebase_RNAseq_e10.5_Neural Epithelium Overlying Lateral Eminence_2500_K5
CoexpressionAtlasFacebaseRNAseq_e10.5_Neural Epithelium Overlying Central Eminence_top-relative-expression-ranked_500_k-means-cluster#4

HOOK1 SYNE2 RB1 PCLO FHOD3 ZDBF2 AKAP9

2.36e-041391877Facebase_RNAseq_e10.5_Neural Epithelium Overlying Central Eminence_500_K4
CoexpressionAtlasdev gonad_e13.5_M_GermCell_Oct_k-means-cluster#2_top-relative-expression-ranked_200

CCDC18 FANCD2 MDN1 HOOK1

2.46e-04351874gudmap_dev gonad_e13.5_M_GermCell_Oct_k2_200
CoexpressionAtlasdev gonad_e12.5_F_GermCellOvary_Oct_k-means-cluster#4_top-relative-expression-ranked_500

CCDC18 FANCD2 MDN1 HOOK1 GLIS3 CEP192

2.73e-041011876gudmap_dev gonad_e12.5_F_GermCellOvary_Oct_k4_500
ToppCellCOVID-19-kidney-PEC|COVID-19 / Disease (COVID-19 only), tissue and cell type

CYP3A5 HOOK1 TRPM3 SYNE2 PKHD1 KAZN ARHGEF28 GLIS3 FHOD3

5.36e-081681939a086c306be430adf0632ba53e98cd8014d2de330
ToppCell390C-Lymphocytic-CD4_T-cell-Treg_cell_3|390C / Donor, Lineage, Cell class and subclass (all cells)

LRSAM1 NCAPG PDP2 ABHD16A ZNF529 ZBTB25 FHOD1 LRRCC1 CCDC180

1.11e-071831939228092290dbb08785c4eda224e3ad03e99e10fab
ToppCellControl-Neu_4|World / 5 Neutrophil clusters in COVID-19 patients

RABGAP1 FANCD2 MGAT5 KLHL6 DNAH10 ARFGEF2 ECPAS PCNT RPAP2

1.17e-071841939ce7f044956613118ee2e9fb6af2455c3166cb414
ToppCell390C-Lymphocytic-CD4_T-cell-Treg_cell_3|CD4_T-cell / Donor, Lineage, Cell class and subclass (all cells)

ERC1 LRSAM1 NCAPG PDP2 ABHD16A ZBTB25 FHOD1 LRRCC1 CCDC180

1.34e-0718719391eed2c1a05e80a7c8f639437c117afe0c18dfb0c
ToppCell3'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CFAP251 SYNE2 AKAP6 DNAH10 SYNE1 CFAP43 PLEKHG4B AKAP9 CCDC180

2.09e-07197193974a2c6cb8fcfe53dd9a2b36492a16c58f38e51c9
ToppCellTracheal-NucSeq|Tracheal / Cell types per location group and 10X technology with lineage, and cell group designations

USP34 VWA8 ERC1 CLASP2 BIRC6 MGAT5 RABGAP1L ARHGEF28 CLASP1

2.27e-07199193994b94b17ca18b8dc27b91da1f2ccf89e03cc7035
ToppCellLV-13._Vascular_Smooth_Muscle|World / Chamber and Cluster_Paper

RABGAP1 ITGA1 UBA2 ITIH5 FRY HES4 LGR6 NPAS4

6.40e-071651938f37fd95adc95d7753cf6e55ae819976513c7ec77
ToppCellLV-13._Vascular_Smooth_Muscle|LV / Chamber and Cluster_Paper

RABGAP1 ITGA1 UBA2 ITIH5 FRY HES4 LGR6 NPAS4

8.38e-071711938e99ecae66530d1ae09330cee408c8f3950b87e67
ToppCellCOVID-19-kidney-Epi_(Mes)|kidney / Disease (COVID-19 only), tissue and cell type

MAP2 CYP3A5 ITGA1 KAZN SYNE1 FHOD3 FRMD4A FRY

1.18e-061791938e7c9dc63f03d3f3746b51a7e3c8393089e2ceb7d
ToppCellCOVID-19-kidney-PCT-S2|COVID-19 / Disease (COVID-19 only), tissue and cell type

TRPM3 SYNE2 PKHD1 ARHGEF28 PCLO GLIS3 FHOD3 PALS2

1.23e-061801938358923e4228035a3e90e2957392089219e90dcd7
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FREM1 FREM2 TRPM3 PKHD1 OTOA DNAH10 PCLO DNAH1

1.45e-0618419382cbed6462fea2622871bb7e49b0df3d984239281
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FREM1 FREM2 TRPM3 PKHD1 OTOA DNAH10 PCLO DNAH1

1.45e-0618419382b19a8c5f823e00812908b23e66bb4e563278aff
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FREM1 FREM2 TRPM3 PKHD1 OTOA DNAH10 PCLO DNAH1

1.45e-061841938ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCell390C-Lymphocytic-CD4_T-cell-Treg_cell_3|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

ERC1 LRSAM1 NCAPG ABHD16A ZBTB25 FHOD1 LRRCC1 CCDC180

1.58e-06186193874eb69a52090f9e2426a47e03a1c478ee0cfec18
ToppCellCOVID-19-kidney|COVID-19 / Disease (COVID-19 only), tissue and cell type

TRPM3 SYNE2 PKHD1 KAZN ARHGEF28 PCLO GLIS3 FHOD3

1.64e-061871938d23aae9419d460b78b1d4092d7acd9108a47cfbe
ToppCellrenal_cortex_nuclei|World / Celltypes from Cells and Nuclei per compartment and clinical group

PDE7A ERC1 TRPM3 RABGAP1L SYNE2 PKHD1 GLIS3 FHOD3

2.00e-061921938e8cc4d08fcfceeab75a02558817e4ccd7dbafe3a
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

KANSL1L FREM2 TRPM3 PKHD1 KAZN ARHGEF28 PCLO FHOD3

2.16e-06194193893c68c31e39fa44c1d05d7d4997f4f086da4e738
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

KANSL1L FREM2 PKHD1 KAZN ARHGEF28 PCLO GLIS3 FHOD3

2.33e-061961938eea66711a16134f86e6c533a5a837ff2e0d7ca7f
ToppCell367C-Fibroblasts-Fibroblast-K_(Pericytes)|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

SPEG ITGA1 SYNE2 AKAP6 UBA2 FRY HES4 LGR6

2.33e-0619619381d94cecd378a829dd8014fc086d7fca48c953a91
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

KANSL1L FREM2 PKHD1 KAZN ARHGEF28 PCLO GLIS3 FHOD3

2.33e-0619619386ce74aa3f0ce3ca284b67e5a4660ffd2cc9611e0
ToppCellNS-control-d_0-4-Epithelial-Ciliated|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

CFAP251 TEKT2 KLHL6 DNAH10 SYNE1 FRMPD2 CFAP43 CCDC180

2.33e-061961938d46ab80554dd3c1cc81e1938ea2acfd5e85c6d2a
ToppCell367C-Fibroblasts-Fibroblast-K_(Pericytes)-|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

SPEG ITGA1 SYNE2 AKAP6 UBA2 FRY HES4 LGR6

2.33e-061961938aacec48285bcb7ccf1b538187071885e3602cc49
ToppCellHealthy_Control-Lymphoid-T|Healthy_Control / Condition, Lineage, Cell class and cell subclass

ITGA1 NCAPG SYNE2 KLRB1 SYNE1 PRR5 DEPDC1 UHRF1

2.61e-061991938f22438fc9c02d0a4d7c936f9420b913aca851ea1
ToppCellCOVID-19_Mild-Neu_2|World / 5 Neutrophil clusters in COVID-19 patients

ADA2 ITGB3 GLB1L3 FHOD3 ZDBF2 FRMD4A PALS2

2.66e-061401937b1429028c52f84127b894b93b55961badcd5246f
ToppCellLPS_anti-TNF-Mesenchymal_myocytic-Pericyte-Pericyte_3|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

ITGA1 AKAP6 SYNE1 FRMD4A LMNA HES4 LGR6 NPAS4

2.71e-0620019389169a9ec8e9ab95d90a64c5a19ac666a5cf82313
ToppCellFrontal_cortex-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)-Syt6-Excitatory_Neuron.Slc17a7.Syt6-Cyp26b1_(Deep_layer_pyramidal_cells)|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

MYH2 CFD LRRC37A ARHGEF18 CCDC180

3.68e-065419354daa84df51cc99113a9f8e86b1ae09bd76a9c991
ToppCellFrontal_cortex-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)-Syt6-Excitatory_Neuron.Slc17a7.Syt6-Cyp26b1_(Deep_layer_pyramidal_cells)-|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

MYH2 CFD LRRC37A ARHGEF18 CCDC180

3.68e-065419352e177a9fd0f7c033dbcfa8b41b76658d8268644c
ToppCellPCW_07-8.5-Epithelial-Epithelial_ciliated-epi_ciliated_(14)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

KCNH7 MCIDAS FREM2 TEKT2 KCNJ11 PKHD1 CFAP43

7.86e-0616519370c714e852f912b5749de4cb0895406673979b2e6
ToppCellPCW_07-8.5-Epithelial-Epithelial_ciliated|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

KCNH7 MCIDAS FREM2 TEKT2 KCNJ11 PKHD1 CFAP43

7.86e-06165193782530f96aaefe28a13bad0474bbad043f127a86c
ToppCellHippocampus-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)-Slc17a6-Excitatory_Neuron.Slc17a6.Grp_(Neuron.Slc17a6.Grp)-|Hippocampus / BrainAtlas - Mouse McCarroll V32

MYH2 TRIML2 PKHD1 DSC1 NPTXR

9.24e-06651935b7bc23af54d6d2f7afd584f4df42c24d7c49e344
ToppCellHippocampus-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)-Slc17a6-Excitatory_Neuron.Slc17a6.Grp_(Neuron.Slc17a6.Grp)|Hippocampus / BrainAtlas - Mouse McCarroll V32

MYH2 TRIML2 PKHD1 DSC1 NPTXR

9.24e-066519353b3630253f5713c4a688c74c4ea0f98c1fe42594
ToppCell5'-GW_trimst-1.5-LargeIntestine-Mesenchymal-Pericytes-angiogenic_pericyte|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ITGA1 NLRC5 FRY LMNA HES4 LGR6 NPAS4

9.92e-061711937285533ca2a6a411773313166bee35542f34d1a3c
ToppCellCiliated_cells-A-Donor_02|World / lung cells shred on cell class, cell subclass, sample id

CFAP251 KCNH7 TEKT2 AKAP6 DNAH10 UBA2 CFAP43

1.20e-0517619371c364155f46b9a7c995bdc2cc2333c437cd90f5b
ToppCellCOVID-19-kidney-Epi_(Mes)|COVID-19 / Disease (COVID-19 only), tissue and cell type

CYP3A5 SYNE2 PKHD1 KAZN ARHGEF28 GLIS3 FHOD3

1.29e-051781937544379f5a6145429762258d426b876bb36c112f5
ToppCellCiliated_cells-B-Donor_06|World / lung cells shred on cell class, cell subclass, sample id

TEKT2 DNAH10 FRMPD2 UBA2 CFAP43 DNAH1 PLEKHG4B

1.38e-051801937bdea5ec6b60fc8c7cce4d71db5da74ac8675e211
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Outer_Medullary_Collecting_Duct_Principal_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ERC1 FREM1 FREM2 TRPM3 FHOD3 SFXN5 FRY

1.43e-051811937aa233b652921848af2257cc3687a7a09c3acfb67
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Outer_Medullary_Collecting_Duct_Principal_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ERC1 FREM1 TRPM3 KAZN FHOD3 SFXN5 FRY

1.54e-051831937b5ede5a0048c585b73c00e88aeddbcaf669347b1
ToppCellLV-15._Ventricular_Cardiomyocyte_III|LV / Chamber and Cluster_Paper

XIRP1 PDE7A ITGAV RABGAP1L AKAP6 FRY PDE4DIP

1.60e-051841937ab7a1620c14a9d9b6be1b47c559931e345e9eef8
ToppCellPCW_05-06-Epithelial-Epithelial_alveolar-distal-epi_SOX9^high_Etv5^high_distal_(10)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

FREM2 HOOK1 PKHD1 ARHGEF28 FRMPD2 FRY MYH14

1.60e-051841937fa4915b0498f3069fd5ef497286445528f75187e
ToppCellfacs-Brain_Non-Myeloid-Striatum-24m-Macroglial-astrocyte|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NDOR1 CCDC18 TRPM3 C4A C4B CLASP1

1.62e-051231936a45d6907c041ad3f3218cd46dccfc25d4bd961cb
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-24m-Epithelial-neuroepithelial_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FREM2 DNAH10 ZDBF2 CFAP43 DNAH1 CCDC180 METTL15

1.65e-05185193705bc89a566b0db90ae06506e067190a4739a0974
ToppCellLV-15._Ventricular_Cardiomyocyte_III|World / Chamber and Cluster_Paper

PDE7A VWA8 RABGAP1L AKAP6 FHOD3 FRY PDE4DIP

1.65e-0518519376baccb26f999145e51b91d94315bf8d4655bef31
ToppCellNS-moderate-d_16-33-Epithelial-Ciliated|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

CFAP251 TEKT2 AKAP6 DNAH10 FRMPD2 CFAP43 CCDC180

1.65e-0518519375e689c2fb36ce3ac2adc8d15f67107f21cf68868
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

TRPM3 SYNE2 PKHD1 KAZN SYNE1 CFAP43 PALS2

1.71e-051861937f0c8de4f6ae9047b9108a47a2af8c5f42bc103b0
ToppCellCOPD-Lymphoid-NK|COPD / Disease state, Lineage and Cell class

BPGM SYNE2 KLRB1 SYNE1 PRR5 MADD LGR6

1.83e-051881937c9a227c8e71b69929d43e9afb8306a95c8163778
ToppCellrenal_medulla_nuclei|World / Celltypes from Cells and Nuclei per compartment and clinical group

KANSL1L ERC1 FREM1 PKHD1 KAZN SYNE1 FRY

1.90e-051891937830d9cd0dd706bce22eb2416f07b2c31c870a05a
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

MAP2 SPEG AKAP6 FRMD4A FRY HES4 LGR6

1.90e-0518919377fbe855bfdb47d35e040b04a80fe4b729a3764e8
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

MAP2 SPEG AKAP6 FRMD4A FRY HES4 LGR6

1.90e-05189193706b35abecd29f902cf251fcc1f6ad33db7ab08a2
ToppCellPCW_07-8.5-Epithelial-Epithelial_airway-epi_proximal_progenitor1_(6)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

FREM2 HOOK1 PKHD1 ARHGEF28 PCLO FRY MYH14

1.90e-0518919377659c7bbd58ee959a159294fb8d17317bbcc5681
ToppCellILEUM-inflamed-(5)_Plasma-(5)_IgA_plasma_cells|(5)_Plasma / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

ZBTB38 GPBP1 ESR2 ANKRD28 KLRB1 AKAP9 LMNA

1.90e-051891937a0634d72bfdd5f93877724ed6480b50a3a046f71
ToppCellLPS_only-Epithelial_alveolar-AT_2-Differentiating_AT1|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SYNE2 KAZN NLRP5 FAM83C PLEKHG4B MYH14

1.94e-0512719365b0adbcafad31a6759c9bdce2f7f9591a8edc450
ToppCellNasal_Brush-Epithelial-Ciliated_2|Nasal_Brush / Tissue, Lineage and Cell class of Lung Cells from 10X

CFAP251 TEKT2 KLHL6 DNAH10 SYNE1 FRMPD2 CFAP43

1.96e-0519019379ce7df056bfb24d70db4c3c4a2c57d89115de877
ToppCellNasal_Brush-Epithelial-Ciliated_2|Epithelial / Tissue, Lineage and Cell class of Lung Cells from 10X

CFAP251 TEKT2 KLHL6 DNAH10 SYNE1 FRMPD2 CFAP43

1.96e-051901937833481ace2800354712e2ce709d5cdfd0aed3d42
ToppCellLPS-antiTNF-Epithelial_alveolar-Mes-Like-Differentiating_AT1|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SPEG FANCD2 PCLO CFAP43 ZNF529 PLEKHG4B

2.03e-0512819362cf0384240a4a663869cf6b27d954236f6214a9a
ToppCellControl-Stromal-SMC|Stromal / Disease state, Lineage and Cell class

MAP2 SPEG ITGA1 AKAP6 FRY HES4 LGR6

2.03e-0519119372da83c493e60ad0278848957645277d76737a188
ToppCelldroplet-Heart-nan-3m-Mesenchymal-atrial_cardiomyocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

XIRP1 HOOK1 KCNJ11 AKAP6 FHOD3 MYH14 PDE4DIP

2.03e-05191193797fb4232417a39801e87725755fd16a57c250209
ToppCellControl-Myeloid-Macrophage_Alveolar|Myeloid / Disease state, Lineage and Cell class

VWA8 CFD MGAT5 KAZN ARHGEF28 ITIH5 FRMD4A

2.03e-051911937a7bb8aba9c59c037d995a77928cc7b4d5cbb82b9
ToppCelldroplet-Heart-nan-3m-Mesenchymal-cardiomyocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

XIRP1 HOOK1 KCNJ11 AKAP6 FHOD3 MYH14 PDE4DIP

2.03e-05191193764070a309d7e3f6001272409ab9ce206d0e7d73f
ToppCellCOVID-19-kidney-CNT|COVID-19 / Disease (COVID-19 only), tissue and cell type

FREM1 FREM2 TRPM3 PKHD1 KAZN GLIS3 FHOD3

2.10e-051921937760c6b9628de9693034b00c5025c5c4df94bb2e8
ToppCelldroplet-Heart-nan-18m-Mesenchymal-cardiomyocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ESR2 KCNJ11 AKAP6 CLASP1 MYH14 PDE4DIP LGR6

2.10e-0519219370bf99e029a06151092db1e8a0dcb45f4e688e771
ToppCelldroplet-Heart-nan-24m-Mesenchymal-cardiomyocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SPEG FREM2 KCNJ11 AKAP6 FHOD3 MYH14 PDE4DIP

2.10e-051921937f6a4e348406a852ace9fb21db8fbdff539217645
ToppCelldroplet-Heart-nan-24m-Mesenchymal-atrial_cardiomyocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SPEG FREM2 KCNJ11 AKAP6 FHOD3 MYH14 PDE4DIP

2.10e-0519219371a0c25106ae08eac912a4edd5fc1a3ee776f69c2
ToppCelldroplet-Heart-nan-18m-Mesenchymal-atrial_cardiomyocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ESR2 KCNJ11 AKAP6 CLASP1 MYH14 PDE4DIP LGR6

2.10e-051921937d766221acfce30cbf2c60b3ae40f6744968b952c
ToppCell368C-Fibroblasts-Fibroblast-K_(Pericytes)|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

SPEG ITGA1 SYNE2 AKAP6 FRY HES4 LGR6

2.17e-0519319375260ac95a15cc43a19909badad0c7e3854da920d
ToppCellwk_08-11-Hematologic-Meg-ery-Definitive_erythroblast|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

BPGM ATG2B FRMD4A EIF5 HBQ1 EP300 PCNT

2.17e-051931937be75abfdf5301cf33df8ee9ed92504d44fdf19a6
ToppCellTCGA-Prostate-Primary_Tumor-Prostate_Adenocarcinoma-Acinar_Adenocarcinoma-6|TCGA-Prostate / Sample_Type by Project: Shred V9

USP34 BIRC6 HOOK1 AKAP9 N4BP2 PTAR1 SMCR8

2.17e-051931937abd71b2cf667ef2b1c4d88acd0c1dd19a12ff659
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

TRPM3 PKHD1 KAZN ARHGEF28 PCLO GLIS3 FHOD3

2.17e-05193193782e8a4c40299ffcdfd5a0da711bb9de6fb8a2eaa
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

KANSL1L TRPM3 PKHD1 ARHGEF28 PCLO GLIS3 FHOD3

2.17e-0519319373866667dd221612589ae50f5c52f73a183a49ce6
ToppCell368C-Fibroblasts-Fibroblast-K_(Pericytes)-|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

SPEG ITGA1 SYNE2 AKAP6 FRY HES4 LGR6

2.17e-0519319375ec917931b438dd0e7fb03eb6af459d3ef6b84ba
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

KANSL1L SYNE2 PKHD1 KAZN ARHGEF28 SYNE1 MYH14

2.24e-051941937e577d9e88390b36b5a09b97fe1026089892275a3
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

KANSL1L FREM2 PKHD1 ARHGEF28 PCLO GLIS3 FHOD3

2.24e-0519419375eaaa81f4b2535f983c424aaef00077089526a5c
ToppCellCOVID-19_Severe-CD8+_Tem|World / disease group, cell group and cell class

ZBTB38 ESR2 SYNE2 KLRB1 SYNE1 PRR5 LGR6

2.24e-05194193760aa16e166894e3fcd82f7a54607c2c02e55b614
ToppCellRA-03._Atrial_Cardiomyocyte|RA / Chamber and Cluster_Paper

PDE7A MGAT5 RABGAP1L AKAP6 FHOD3 FRY PDE4DIP

2.24e-051941937c3535f7cc0076653c72db582047cff053c322397
ToppCellPCW_05-06-Epithelial|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

FREM2 HOOK1 PKHD1 ARHGEF28 FRY MYH14 PKP3

2.24e-05194193747a1369c22fcbfe00b08376eb610a61c355548db
ToppCellPCW_05-06-Epithelial-Epithelial_alveolar-distal-epi_CTGF^high_distal_(3)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

FREM2 HOOK1 PKHD1 ARHGEF28 FRY MYH14 PKP3

2.24e-051941937c5ef4ff73b4e51530656002e3a2fb7264cdf533d
ToppCelldroplet-Limb_Muscle-MUSCLE|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

USP34 ERC1 BACH1 ITGA1 ASAP1 AKAP9 EIF5

2.24e-051941937e3d63874111d1e8da3977329426e4dcf68d6de87
ToppCellPCW_13-14-Epithelial-Epithelial_proliferating-epi_proliferating3_(5)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

FREM2 HOOK1 PKHD1 ARHGEF28 PLEKHG4B FRY PKP3

2.24e-051941937c011cd59bb4ca4134331cba0f5d73bdbd7011d64
ToppCellmoderate-Epithelial-Ciliated|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

CFAP251 KLHL6 DNAH10 SYNE1 FRMPD2 CFAP43 CCDC180

2.32e-0519519373486eae5fdb062a75a907b896c9d7b396d2aa195
ToppCellPBMC_fresh-frozen-Severe-critical_convalescent_d42-56-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c04-COTL1|Severe-critical_convalescent_d42-56 / Compartment, severity and other cell annotations on 10x 3' data (130k)

ZBTB38 SYNE2 NLRC5 KLRB1 SYNE1 PRR5 LGR6

2.32e-05195193714a6466524c22920daa622fbc710daf1defb46c3
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

KANSL1L PKHD1 KAZN ARHGEF28 PCLO GLIS3 FHOD3

2.32e-0519519376477e6e7be5bd8eb99119a12ae16334ccddecd43
ToppCell10x5'v1-week_12-13-Hematopoietic-erythroid-mid_erythroid|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

BPGM PRR5 KIAA1586 FRMD4A EIF5 NPRL3 HBQ1

2.47e-051971937d8f99a9f2367c8bc9308b0c64d0226875262927a
ToppCellTracheal-10x5prime-Epithelial-Epi_airway_ciliated-Deuterosomal|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

MCIDAS TEKT2 LRRC37A FRMPD2 DEPDC1 DNAH1 CCDC180

2.47e-0519719376e4a411ef823ce9e16f420e185e21fa19d13af34
ToppCellcontrol-Epithelial-Ciliated|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

CFAP251 KLHL6 DNAH10 SYNE1 FRMPD2 CFAP43 CCDC180

2.47e-051971937e453d085182364ca347cbcc9dc995c62c3353016
ToppCellcontrol-Epithelial-Ciliated|control / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

CFAP251 KLHL6 DNAH10 SYNE1 FRMPD2 CFAP43 CCDC180

2.47e-051971937d4e963c1f82996371bf3d63578ee9fce8e00c5a8
ToppCelldroplet-Lung-immune-endo-depleted-3m-Myeloid-Neutrophil|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RASGRP4 RBM12B MDN1 ARHGEF28 ARFGEF2 EP300

2.52e-051331936292ecfcadbaf15e0d34a3ab9bf511ab1065888bd
ToppCelldroplet-Lung-immune-endo-depleted-3m-Myeloid-neutrophil|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RASGRP4 RBM12B MDN1 ARHGEF28 ARFGEF2 EP300

2.52e-051331936f6e9a1301a3379847b215303a9b0c028841e2cc0
ToppCellPosterior_cortex-Neuronal-Excitatory-eN1(Slc17a7)-eN1_1-Calb1-Excitatory_Neuron.Slc17a7-Slc17a6.Calb1-Rorb-Il1rapl2_(Layer_5b)|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

WDR64 ESR2 ITGB3 OTOA HBQ1

2.55e-05801935402aba070f0728ebda9db7a8fa85441533755ff4
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

ITGA1 ASAP1 MDN1 KAZN SYNE1 GLIS3 LMNA

2.56e-051981937a860246bcea847249a78fd2e86ed8e04371060db
ToppCellPBMC-Control-Lymphocyte-T/NK-Other_T|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

CTNNAL1 NCAPG SYNE2 KLRB1 SYNE1 DEPDC1 UHRF1

2.56e-05198193780b105a7c7d00ea3b5e586831fbb755bd84f9d1a
ToppCellcritical-Epithelial-Ciliated|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

CFAP251 TEKT2 DNAH10 SYNE1 FRMPD2 CFAP43 CCDC180

2.56e-051981937ee2c8385c0bf4ea9f5c9517b52cf131af3fbdd40
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

MAP2 KAZN SYNE1 PCLO FRMD4A FRY PALS2

2.56e-0519819374ca5ff320905ab4ff60ed90a5522227c782142a6
ToppCellPBMC-Control-Lymphocyte-T/NK-Other_T|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

CTNNAL1 NCAPG SYNE2 KLRB1 SYNE1 DEPDC1 UHRF1

2.56e-051981937c73e906d2d12d6eba0e606958be16e63a2292cd0
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

KCNH7 MAP2 KAZN PCLO FRMD4A FRY PALS2

2.56e-0519819370ff30edfd3c133a42e8cb96e1631a1143215f808
ToppCellBrain_organoid-organoid_Kanton_Nature-Organoid-4M|organoid_Kanton_Nature / Sample Type, Dataset, Time_group, and Cell type.

MAP2 MYCBP2 BACH1 RABGAP1 CLASP1 AKAP9 PDE4DIP

2.64e-051991937b2d7dea11207cca63d688f8051143850b29dbdf0
ToppCellBronchus_Control_(B.)-Epithelial-TX-Ciliated|Bronchus_Control_(B.) / Sample group, Lineage and Cell type

CFAP251 TEKT2 DNAH10 SYNE1 FRMPD2 CFAP43 CCDC180

2.73e-0520019376a2ccc71a0cbe04a542c379b28b5006de53981c3
ToppCellLPS_IL1RA_TNF-Mesenchymal_myocytic-Pericyte-Pericyte_3|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

ITGA1 AKAP6 SYNE1 FRMD4A LMNA HES4 LGR6

2.73e-052001937c06426f877919bdd267ea2fd7e7973c6619832ae
ToppCellLPS_only-Epithelial_alveolar-AT_1-Differentiating_AT1|LPS_only / Treatment groups by lineage, cell group, cell type

TRPM3 SYNE2 PKHD1 MYH14 PKP3 FHOD1 CEP170B

2.73e-0520019372dadf317a42a7e27cc1fac74f91b806c93a57108
ToppCellTracheal-10x5prime-Epithelial-Epi_airway_ciliated|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

CFAP251 TEKT2 DNAH10 FRMPD2 CFAP43 DNAH1 CCDC180

2.73e-05200193731d75c26055177d656df1fbb10b764cebd61e122
ToppCellTracheal-10x5prime-Epithelial-Epi_airway_ciliated-Ciliated|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

CFAP251 TEKT2 DNAH10 FRMPD2 CFAP43 DNAH1 CCDC180

2.73e-052001937e1dce91c6c531bb212002a14705e496d77ad3490
ToppCellCOVID-19_Severe-MAIT|COVID-19_Severe / disease group, cell group and cell class

ZFR2 SYNE2 KLRB1 PCDHGA5 PRR5 EYS

4.94e-051501936923ea7ecc0aa05fb0396082cd9c3d1594135f1e0
DrugAC1L1SX8

CYP3A7 CYP3A4 CYP3A5 PEG10 CFD ABCC1

5.50e-09181916CID000060278
Drug3,3'-diindolylmethane

TRIM25 CYP3A4 CYP3A5 ESR2 CFD TKT EP300

5.85e-06821917CID000003071
Drugchlorpromazine hydrochloride; Down 200; 1uM; MCF7; HT_HG-U133A

USP34 MAN2C1 VWA8 BPGM LMF1 ARFGEF2 SETD4 PKP3 NPRL3 PALS2

7.39e-06199191106936_DN
DrugAC1L1K7W

CYP3A7 TRIM25 CYP3A4 CYP3A5 ESR2

9.00e-06341915CID000005377
DrugAlfentanil

CYP3A7 CYP3A4 CYP3A5

1.14e-0561913ctd:D015760
Drug4-hydroxycyclophosphamide

CYP3A4 CYP3A5 PEG10 ABCC1 SYNE1

1.58e-05381915CID000099735
DrugTeniposide

CYP3A4 CYP3A5 ESR2 ABCC1

2.57e-05211914ctd:D013713
Drugmethoxychlor

TRIM25 CYP3A4 CYP3A5 ESR2 CUX2 RB1

3.18e-05721916CID000004115
DrugMianserine hydrochloride [21535-47-7]; Up 200; 13.2uM; MCF7; HT_HG-U133A

USP34 SPEG RABGAP1 ITGB3 ALMS1 RABGAP1L RB1 ITIH5 FRMD4A

3.26e-0518919192231_UP
DrugIndomethacin [53-86-1]; Down 200; 11.2uM; PC3; HT_HG-U133A

TRIM25 NAA60 SPEG DOCK6 LMF1 SYNE1 TRIM23 NPTXR PKP3

3.99e-0519419195049_DN
DrugGlucocorticoids

CYP3A7 CYP3A4 CYP3A5 FIBIN RB1

4.09e-05461915ctd:D005938
Drug2-propylpentanoic acid; Down 200; 200uM; MCF7; HT_HG-U133A

USP34 MAN2C1 ALMS1 RABGAP1L DOCK6 LMF1 TRIM23 PKP3 RPAP2

4.50e-0519719196934_DN
DrugCorynanthine hydrochloride [66634-44-4]; Down 200; 10.2uM; MCF7; HT_HG-U133A

ERC1 DOCK6 LMF1 PRR5 FRMD4A MYH14 PDE4DIP PALS2 CDK3

4.68e-0519819192786_DN
DrugPD138142-15

CYP3A4 CYP3A5 CFD

4.70e-0591913CID003025787
DrugAC1MHWVC

CYP3A4 CYP3A5 SYNE1

4.70e-0591913CID003034089
DrugS 840

CYP3A7 CYP3A4 CYP3A5

4.70e-0591913CID000096338
DrugMerbromin [129-16-8]; Down 200; 5uM; PC3; HT_HG-U133A

MAN2C1 UBE4B VWA8 ERC1 SPEG LMF1 SYNE1 NPTXR PDE4DIP

4.87e-0519919197398_DN
DrugRibostamycin sulfate salt [53797-35-6]; Down 200; 7.2uM; MCF7; HT_HG-U133A

RABGAP1 KAZN DOCK6 RB1 LMNA MYH14 PDE4DIP CDK3 SYMPK

4.87e-0519919196765_DN
Drugoxepin

CYP3A5 SYNE1 SYMPK

6.68e-05101913CID006451477
Drug4-hydroxymidazolam

CYP3A7 CYP3A4 CYP3A5

6.68e-05101913CID000124449
DrugAHMA

CYP3A4 CYP3A5 IARS1

6.68e-05101913CID000216240
Drug4-hydroxymidazolam

CYP3A4 CYP3A5

7.00e-0521912ctd:C042940
Drug2,3-epoxyoxepin

CYP3A5 SYMPK

7.00e-0521912CID000171199
Drugphoratoxon

CYP3A5 FANCD2

7.00e-0521912CID000075780
Drugnorverapamil

CYP3A4 CYP3A5

7.00e-0521912ctd:C016904
Drug5,6-dihydro-2H-pyran-2-one

CYP3A4 CYP3A5

7.00e-0521912CID000520660
DrugCTK1A9023

CYP3A5 SYMPK

7.00e-0521912CID010329262
Drugnotopterol

CYP3A4 CYP3A5

7.00e-0521912CID005320227
DrugN-acetyl-S--(1,2,3,4,4-pentachlorobutadienyl)cysteine sulfoxide

CYP3A4 CYP3A5

7.00e-0521912ctd:C114289
Drug1-deoxy-1-imino-d-erythrose 4-phosphate

TKTL2 TKT

7.00e-0521912CID000443712
DrugAC1L9F1Q

TKTL2 TKT

7.00e-0521912CID000443711
Drug6 beta-hydroxytestosterone

CYP3A4 CYP3A5

7.00e-0521912ctd:C025591
DrugCQA 206-291

CYP3A4 CYP3A5

7.00e-0521912ctd:C059483
DrugAC1LCS6E

TKTL2 TKT

7.00e-0521912CID000636406
Drugfructus schizandrae, radix ginseng, radix ophiopogonis drug combination

CYP3A4 CYP3A5

7.00e-0521912ctd:C009252
Drugtariquidar

CYP3A4 CYP3A5 ITGAV ABCC1

7.24e-05271914CID000148201
DrugAC1L1CGL

CYP3A4 CYP3A5 ESR2 ALMS1

7.24e-05271914CID000001889
DrugMCDF

TRIM25 CYP3A5 ERC1 ESR2

8.39e-05281914CID000114900
DrugE 5110

CYP3A4 CYP3A5 C4A

9.13e-05111913CID006438164
Drugs-collidine

CYP3A4 CYP3A5 SYMPK

9.13e-05111913CID000007953
DrugTroleandomycin

CYP3A7 CYP3A4 CYP3A5

9.13e-05111913ctd:D014217
DrugAC1L5R4P

CYP3A4 CYP3A5 PCNT

9.13e-05111913CID000254855
DrugTicalopride

CYP3A7 CYP3A4 CYP3A5

9.13e-05111913CID000216236
DiseaseEmery-Dreifuss muscular dystrophy (implicated_via_orthology)

HOOK1 SYNE2 SYNE1 LMNA

7.43e-07121874DOID:11726 (implicated_via_orthology)
DiseaseAutosomal dominant Emery-Dreifuss muscular dystrophy

SYNE2 SYNE1 LMNA

9.97e-0741873cv:CN293514
Diseasetacrolimus measurement

CYP3A7 CYP3A4 CYP3A5

9.97e-0741873EFO_0008458
DiseaseMalignant neoplasm of breast

XIRP1 MAN2C1 CYP3A4 ESR2 WDR53 LRRC37A HOOK1 SYNE2 NLRC5 CTU1 AKAP6 ABCC1 PCDHGB6 RB1 SYNE1 ARFGEF2 NUP214 AKAP9 N4BP2 EIF5 LGR6 EP300

1.40e-06107418722C0006142
DiseaseAutosomal Recessive Emery-Dreifuss Muscular Dystrophy

SYNE2 SYNE1 LMNA

2.48e-0651873C1450051
DiseaseAutosomal Dominant Emery-Dreifuss Muscular Dystrophy (disorder)

SYNE2 SYNE1 LMNA

2.48e-0651873C0410190
DiseaseEmery-Dreifuss muscular dystrophy

SYNE2 SYNE1 LMNA

4.94e-0661873cv:C0410189
DiseaseMuscular Dystrophy, Emery-Dreifuss

SYNE2 SYNE1 LMNA

4.94e-0661873C0410189
DiseaseX-Linked Emery-Dreifuss Muscular Dystrophy

SYNE2 SYNE1 LMNA

8.60e-0671873C0751337
DiseaseMarles Greenberg Persaud syndrome

FREM1 FREM2

4.00e-0521872C1855425
Diseasereticulocyte measurement

USP34 NDOR1 VWA8 ITGA1 BIRC6 CFD BPGM HOOK1 SYNE2 ARHGEF28 COPZ1 DNAH10 CLASP1 ARFGEF2 BEND3 ECPAS FAM83C NPRL3 HBQ1

4.38e-05105318719EFO_0010700
Diseaselymphocyte count

CYP3A7 ZBTB38 UBE4B CYP3A4 CYP3A5 ITGA1 BPGM ALMS1 C19orf44 NLRC5 LRRC8C ABCC1 DNAH10 PCDHGB6 RB1 PCDHGA11 PCDHGA5 GLIS3 BEND3 ARHGEF18 ZBTB25 PKP3 RPAP2

5.75e-05146418723EFO_0004587
Diseasesystemic lupus erythematosus (implicated_via_orthology)

TLR7 C4A C4B EP300

1.59e-04431874DOID:9074 (implicated_via_orthology)
Diseasemetabolonic lactone sulfate measurement

CYP3A7 CYP3A4 CYP3A5

2.25e-04191873EFO_0800659
DiseaseFraser syndrome (implicated_via_orthology)

FREM1 FREM2

2.38e-0441872DOID:0090001 (implicated_via_orthology)
DiseaseWallerian Degeneration

UBE4B CCAR2

2.38e-0441872C0043020
Diseaseestrone conjugate measurement

CYP3A7 CYP3A4

2.38e-0441872EFO_0007971
DiseaseFEV/FEC ratio

USP34 MAP2 ERC1 SPEG ITGA1 ITGAV ASAP1 SPTBN5 FREM2 MGAT5 SYNE2 CTU1 KLHL6 AKAP6 ARHGEF28 PCDHGA5 GLIS3 ARHGEF18 FRMD4A

3.17e-04122818719EFO_0004713
Diseasereticulocyte count

USP34 NDOR1 VWA8 ITGA1 BIRC6 CFD BPGM HOOK1 SYNE2 C4B ARHGEF28 DNAH10 CLASP1 BEND3 FAM83C NPRL3 HBQ1

3.76e-04104518717EFO_0007986
DiseaseHydrophthalmos

MYOC GLIS3

3.95e-0451872C0020302
Diseasetauro-beta-muricholate measurement

CYP3A7 CYP3A4

3.95e-0451872EFO_0800213
Diseaseglyco-beta-muricholate measurement

CYP3A7 CYP3A4

3.95e-0451872EFO_0800569
DiseaseHDL cholesterol change measurement

ESR2 SYNE2 DOCK6

4.60e-04241873EFO_0007805
DiseaseParoxysmal atrial fibrillation

USP34 UBE4B ESR2 SYNE2 AKAP6 DNAH10

4.95e-041561876C0235480
Diseasefamilial atrial fibrillation

USP34 UBE4B ESR2 SYNE2 AKAP6 DNAH10

4.95e-041561876C3468561
DiseasePersistent atrial fibrillation

USP34 UBE4B ESR2 SYNE2 AKAP6 DNAH10

4.95e-041561876C2585653
Diseasechronotype measurement

USP34 MYCBP2 VWA8 ESR2 SLC10A7 BIRC6 FBXL3 RABGAP1L NXF3 PKHD1 KAZN COPZ1 MADD DNAH1 METTL15

5.30e-0488218715EFO_0008328
DiseaseMammary Carcinoma, Human

MAN2C1 CYP3A4 ESR2 LRRC37A CTU1 ABCC1 PCDHGB6 RB1 SYNE1 LGR6 EP300

5.58e-0452518711C4704874
DiseaseMammary Neoplasms, Human

MAN2C1 CYP3A4 ESR2 LRRC37A CTU1 ABCC1 PCDHGB6 RB1 SYNE1 LGR6 EP300

5.58e-0452518711C1257931
DiseaseAtrial Fibrillation

USP34 UBE4B ESR2 SYNE2 AKAP6 DNAH10

5.66e-041601876C0004238
DiseaseColorectal Carcinoma

MAP2 ESR2 AXIN2 NCAPG PKHD1 AKAP6 ABCC1 SYNE1 FRMPD2 SETD4 AKAP9 LGR6 EP300

5.73e-0470218713C0009402
DiseaseMammary Neoplasms

MAN2C1 CYP3A4 ESR2 LRRC37A CTU1 ABCC1 PCDHGB6 RB1 SYNE1 LGR6 EP300

5.75e-0452718711C1458155
Diseasedehydroisoandrosterone sulfate DHEA-S measurement

CYP3A7 CYP3A4

5.89e-0461872EFO_0021119
Diseaseandrostenediol (3beta,17beta) monosulfate (1) measurement

CYP3A7 CYP3A4

5.89e-0461872EFO_0800294
DiseaseBreast Carcinoma

MAN2C1 CYP3A4 ESR2 LRRC37A CTU1 ABCC1 PCDHGB6 RB1 SYNE1 LGR6 EP300

6.82e-0453818711C0678222
Diseasestimulant use measurement

ASAP1 RB1 EYS

7.30e-04281873EFO_0600076
DiseaseX-24574 measurement

CYP3A7 CYP3A4

8.22e-0471872EFO_0800897
Diseasealcohol consumption measurement

ZBTB38 KCNH7 BIRC6 SPTBN5 ALMS1 RBM27 RABGAP1L PKHD1 AKAP6 CUX2 PCLO FRMD4A AKAP9 TKT HES4 METTL15 EP300 IL27

9.72e-04124218718EFO_0007878
DiseaseAutistic behavior

TRPM3 CUX2

1.09e-0381872C0856975
DiseaseUnilateral agenesis of kidney

FREM1 FREM2

1.09e-0381872C0266294
Diseaseandrosterone sulfate measurement

CYP3A7 CYP3A4 BIRC6

1.19e-03331873EFO_0021117
DiseaseComplement deficiency disease

CFD C4A C4B

1.19e-03331873C0272242
Diseaseneutrophil-to-lymphocyte ratio

CYP3A5 C19orf44 NLRC5 CUX2 ARHGEF18 RPAP2

1.20e-031851876EFO_0008447
DiseaseAbnormality of refraction

ZBTB38 BACH1 BIRC6 ASAP1 AXIN2 AKAP6 PCLO FRMPD2 GLIS3 FRY CCAR2 METTL15

1.28e-0367318712HP_0000539
Diseaseandrostenediol (3beta,17beta) disulfate (1) measurement

CYP3A7 CYP3A4

1.40e-0391872EFO_0800278
Diseaseopen-angle glaucoma

MYOC ITGB3 MGAT5 PKHD1 PCDHGA5 MADD

1.42e-031911876EFO_0004190
Diseasebirth weight, parental genotype effect measurement

CYP3A7 ZBTB38 CYP3A4 GLIS3 ARFGEF2 IL27

1.45e-031921876EFO_0004344, EFO_0005939
DiseaseAntihypertensive use measurement

PDP2 ARHGEF18 MADD LMNA TKT NPRL3 METTL15

1.57e-032651877EFO_0009927
DiseaseShort Stature, CTCAE

SLC10A7 FBXL3

1.74e-03101872C2919142
DiseaseShort stature

SLC10A7 FBXL3

1.74e-03101872C0349588
Disease4-androsten-3alpha,17alpha-diol monosulfate (3) measurement

CYP3A7 CYP3A4

1.74e-03101872EFO_0022090
Diseasepleural tuberculosis (is_marker_for)

ADA2 IL27

1.74e-03101872DOID:106 (is_marker_for)
Disease5alpha-androstan-3beta,17alpha-diol disulfate measurement

CYP3A7 CYP3A4

1.74e-03101872EFO_0800289
Diseaselong QT syndrome (implicated_via_orthology)

KCNH7 ARHGAP36

1.74e-03101872DOID:2843 (implicated_via_orthology)
Diseaseurate measurement

USP34 CYP3A7 CYP3A4 BIRC6 MGAT5 PKHD1 ANKRD28 CUX2 GLIS3 DNAH1 LMNA TKT UHRF1 PALS2

1.78e-0389518714EFO_0004531
Diseasepost-traumatic stress disorder symptom measurement

CYP3A4 SYNE1 GLIS3 METTL15

1.86e-03821874EFO_0008535
DiseaseGraves' disease (is_implicated_in)

ESR2 C4A C4B

1.94e-03391873DOID:12361 (is_implicated_in)
Diseaseurate measurement, bone density

WDR64 UBE4B ERC1 CLASP2 FREM1 RABGAP1L KAZN AKAP6 SYNE1 DNAH1 EYS

2.08e-0361918711EFO_0003923, EFO_0004531
Diseaseanti-SARS-CoV-2 IgG measurement, response to COVID-19 vaccine

ADA2 FHOD3

2.12e-03111872EFO_0803358, EFO_0803362
DiseaseDNA repair protein RAD51 homolog 4 measurement

CYP3A7 CYP3A4

2.12e-03111872EFO_0801531
Diseaseandrostenediol (3beta,17beta) monosulfate (2) measurement

CYP3A7 CYP3A4

2.12e-03111872EFO_0800295
Diseaseovarian reserve

ITIH5 NPRL3

2.53e-03121872EFO_0004770
Diseasemethionine sulfone measurement

CYP3A4 ALMS1

2.53e-03121872EFO_0800072
Disease5alpha-androstan-3beta,17beta-diol monosulfate (2) measurement

CYP3A7 CYP3A4

2.53e-03121872EFO_0800291
Diseaseatrial fibrillation

USP34 UBE4B ESR2 SYNE2 AKAP6 CUX2 DNAH10 HES4

2.64e-033711878EFO_0000275
Diseaseage at onset, Myopia

ZBTB38 TRIM25 TRPM3 AKAP6 FRMPD2

2.73e-031501875EFO_0004847, HP_0000545
DiseaseDiabetes, Autoimmune

KCNJ11 GLIS3 IL27

2.74e-03441873C0205734
DiseaseBrittle diabetes

KCNJ11 GLIS3 IL27

2.74e-03441873C0342302
DiseaseDiabetes Mellitus, Sudden-Onset

KCNJ11 GLIS3 IL27

2.74e-03441873C4554117
DiseaseDiabetes Mellitus, Ketosis-Prone

KCNJ11 GLIS3 IL27

2.74e-03441873C3837958
DiseaseDiabetes Mellitus, Insulin-Dependent

KCNJ11 GLIS3 IL27

2.92e-03451873C0011854
Diseasehematologic cancer (implicated_via_orthology)

CUX2 UBA2

2.98e-03131872DOID:2531 (implicated_via_orthology)
Diseaseandrostenediol (3alpha, 17alpha) monosulfate (3) measurement

CYP3A7 CYP3A4

2.98e-03131872EFO_0800293
Disease5alpha-pregnan-3beta,20beta-diol monosulfate (1) measurement

CYP3A7 CYP3A4

2.98e-03131872EFO_0800284
Diseaseosteoarthritis

RABGAP1 RABGAP1L KAZN DNAH10 GLIS3 METTL15

3.01e-032221876MONDO_0005178
Diseaseglucose measurement

ZBTB38 MYCBP2 VWA8 LRRC37A KCNJ11 CUX2 GLIS3 MADD

3.05e-033801878EFO_0004468
Diseasemetabolite measurement

CFAP251 CYP3A5 ALMS1 FIBIN SYNE2 ABCC1 GLB1L3 TKT RFXANK ZMYM1

3.18e-0356018710EFO_0004725
Diseasereaction time measurement

KCNH7 FIBIN RABGAP1L PKHD1 AKAP6 CUX2 DNAH10 CEP192 N4BP2 METTL15 PPP1R16A

3.32e-0365818711EFO_0008393
DiseaseX-21470 measurement

CYP3A7 CYP3A4

3.46e-03141872EFO_0800817
Diseasediacylglycerol 42:7 measurement

ESR2 SYNE2

3.46e-03141872EFO_0020068
Disease5alpha-androstan-3alpha,17alpha-diol monosulfate measurement

CYP3A7 CYP3A4

3.46e-03141872EFO_0800283
DiseaseCardiomyopathy, Dilated

AXIN2 ALMS1 LMNA

3.51e-03481873C0007193
DiseaseCardiomyopathy, Familial Idiopathic

AXIN2 ALMS1 LMNA

3.94e-03501873C1449563
Diseaseinfant head circumference

ZBTB38 ARFGEF2

3.97e-03151872EFO_0004577
Disease16a-hydroxy DHEA 3-sulfate measurement

CYP3A7 CYP3A4

3.97e-03151872EFO_0800301
DiseaseHbA1c measurement

CYP3A7 NDOR1 ZBTB38 HOOK1 KCNJ11 ABCC1 CUX2 CLASP1 GLIS3 MADD NPRL3

4.02e-0367518711EFO_0004541
DiseaseX-21410 measurement

CYP3A7 CYP3A4

4.52e-03161872EFO_0800813
Diseaseleptin measurement, type 2 diabetes mellitus

KCNJ11 GLIS3

4.52e-03161872EFO_0005000, MONDO_0005148
DiseaseMonogenic diabetes

KCNJ11 LMNA

4.52e-03161872C3888631
Diseaseandro steroid monosulfate C19H28O6S (1) measurement

CYP3A7 CYP3A4

4.52e-03161872EFO_0800305
Diseasechronic obstructive pulmonary disease

ZBTB38 WDR64 MCIDAS SPEG ITGA1 SLC10A7 AKAP6 ARHGEF28 PCDHGA5 GLIS3 FRMD4A

4.63e-0368818711EFO_0000341
Diseasecardioembolic stroke

USP34 MYOC ESR2 HOOK1 SYNE2

4.66e-031701875EFO_1001976
DiseaseSmall cell carcinoma of lung

RB1 ZDBF2 EP300

4.90e-03541873C0149925
DiseaseAstrocytosis

ITGA1 ITGB3

5.10e-03171872C3887640
DiseaseAntibody Deficiency Syndrome

CFD C4A

5.10e-03171872C0003257
Diseasesphingomyelin 14:0 measurement

TRPM3 SYNE2

5.10e-03171872EFO_0010390
Diseaselevel of Sphingomyelin (d32:1) in blood serum

ESR2 SYNE2

5.10e-03171872OBA_2045173
DiseaseGliosis

ITGA1 ITGB3

5.10e-03171872C0017639
Diseaseobsolete_red blood cell distribution width

CFAP251 BACH1 BIRC6 HOOK1 RBM27 RABGAP1L SYNE2 DOCK6 ABCC1 COPZ1 CLASP1 PCDHGA5 FRMD4A SMCR8 HBQ1 EP300 IL27

5.51e-03134718717EFO_0005192
Disease5alpha-androstan-3alpha,17beta-diol monosulfate (1) measurement

CYP3A7 CYP3A4

5.72e-03181872EFO_0800288

Protein segments in the cluster

PeptideGeneStartEntry
ELLLLAKESSRSNHT

TMEM62

211

Q0P6H9
LELKLEESHNRFSAT

CCAR2

836

Q8N163
LTLARDKHLEFSSLR

EP300

1631

Q09472
KESLLKERDHILSTL

BACH1

596

O14867
RTQLLFSHEEELSKL

AKAP9

626

Q99996
DDLLETHSHFLARLK

ARHGEF18

496

Q6ZSZ5
SLLSSQLELHSREEK

CFAP43

991

Q8NDM7
LRVLDTSDALKAFHD

BIRC6

3086

Q9NR09
SVKLHLETDSLALVA

C4B

586

P0C0L5
LLRHTKEIVSDLIDS

AKAP4

371

Q5JQC9
ARSLVILKHSSLFLD

ALS2

766

Q96Q42
SKETESHKALSDLEL

CYP3A5

281

P20815
RALEKHADSILALAS

ABHD16A

51

O95870
KHLDVDLDRQSLSSI

ARFGEF2

1501

Q9Y6D5
LPDRHLTEDALKISS

ALMS1

2156

Q8TCU4
GHETSALLILEKITD

ANKRD28

901

O15084
SRLEKLKLELESRHS

AXIN2

376

Q9Y2T1
KELDEALHSLEFSRT

CCDC180

261

Q9P1Z9
HLILKETETALAALE

CEP170B

911

Q9Y4F5
HSALKATQAELLELR

CUX2

211

O14529
ELAKDHSDLSRLTEL

ASTE1

421

Q2TB18
EAHIELLRDSTTDSK

ETNPPL

461

Q8TBG4
SSSTLRIILDEAALH

ATG2B

1276

Q96BY7
ERDTLAHSAPLLTEK

CFAP251

426

Q8TBY9
LDARLFLDHDKTLQT

RB1

331

P06400
VHLKNLSLSIDERDL

RBM12B

286

Q8IXT5
HADARTSRTLLLLAK

RASA4

491

O43374
ELLDTELDLHKRLSS

RBM27

901

Q9P2N5
ELDLHKRLSSGEDTT

RBM27

906

Q9P2N5
SLAEKETHLTNLRAE

ERC1

901

Q8IUD2
LEADKIRPLSHLESD

PGBD4

46

Q96DM1
HADARTSRTLLLLAK

RASA4B

491

C9J798
SIHSLSELERLKLQE

ARHGAP36

51

Q6ZRI8
SDTLERLLKALHKIT

ARHGAP36

341

Q6ZRI8
SDSDITVLRHLEKLG

RIMKLA

81

Q8IXN7
DREKETVHDLLLTAL

PCDHGA5

201

Q9Y5G8
LDREKEAAHLLLLTA

PCDHGA11

201

Q9Y5H2
LEKLLDREEQRSHSL

PCDHGB6

196

Q9Y5F9
SQLHSKVDLLSLEVS

BEND3

211

Q5T5X7
HLKKRSSSLDALDAD

ARHGEF28

471

Q8N1W1
IDHDLLLLQLSEKAT

CFD

111

P00746
DSLVLDSHKKTSVLR

OTOA

666

Q7RTW8
HELVTSKIALRKDLD

RABGAP1

861

Q9Y3P9
ELLKHTKLDIVDSLS

NXF3

411

Q9H4D5
LSLKTEELTSALVHL

SLC10A7

56

Q0GE19
RHLSETALGERTKLE

KANSL1L

711

A0AUZ9
ALSEKRTLEGELHDL

LMNA

151

P02545
ASRALSLRKHLDLIS

MDN1

3791

Q9NU22
TDHATALRSQLDLKD

KAZN

216

Q674X7
GILRLADTHSLDSLK

KLHL6

176

Q8WZ60
LLVEEKSSALLHDLR

MADD

231

Q8WXG6
LLLDIIDSLASHISD

LZTR1

816

Q8N653
ELIVTRELSAKHSLL

EYS

1326

Q5T1H1
DSSRKLAHLLNAVTD

ESR2

421

Q92731
RSKDLTHAISILESA

LRRC37A

1271

A6NMS7
LRQTKDALFTILHDL

ITIH5

311

Q86UX2
LGHDIRISASLAELK

MGAT5

311

Q09328
SLLSLATIKVLDLHD

LRSAM1

76

Q6UWE0
EAFSTLHSLVKLDLT

LGR6

416

Q9HBX8
LLESLKDHISTTAQD

NAA60

116

Q9H7X0
DVLSSSLEAEHRLLK

GPBP1

376

Q86WP2
TSLLKQDSDLSLELH

KCNH7

1141

Q9NS40
VELLLTSDGEKHVLS

GLB1L3

251

Q8NCI6
SKILKVEDRDSLHIS

FREM2

1681

Q5SZK8
SKETESHKALSDLEL

CYP3A4

281

P08684
DTRHSVATAADLELK

ECPAS

271

Q5VYK3
EDHSLLEALTLASAR

KCNJ11

351

Q14654
IRLSKELSSTEAQLH

MYH14

1321

Q7Z406
FSLHEKDLSKTDRLL

PCLO

4066

Q9Y6V0
HRLQLSLDDSISEIK

KIAA1586

421

Q9HCI6
KASEKLLASIDIDHT

MYH2

746

Q9UKX2
DILLSLIAAATHDLD

PDE7A

241

Q13946
SSDSELLRDILHKTV

EEF2KMT

41

Q96G04
LLASLSEHERAAILS

NPRL3

486

Q12980
STEHILISDADTKLD

FREM1

796

Q5H8C1
STKALLELTELLASH

RASGRP4

316

Q8TDF6
KTHRTDSEIALLEGL

COPZ1

51

P61923
LLSLLHREKNKEESD

DEPDC1

346

Q5TB30
EELSHLEVAKSLSAL

PEG10

216

Q86TG7
EATKARLSSLESLLH

MYOC

86

Q99972
RTESDDLHTFLLEIK

NUP214

741

P35658
ISRSRHLKSLDLTDN

NLRP5

1061

P59047
SSRALLKHLEGISDE

BPGM

191

P07738
SDLSLHVATTEKDLL

ITGA1

816

P56199
LVALSFHSLEDRIVK

METTL15

316

A6NJ78
VLALEKERVALSHSS

NPTXR

246

O95502
LHTLEELKSDLSRPT

PCNT

3016

O95613
SLHELEREKLLEFSS

NDOR1

321

Q9UHB4
ALRAATSLEELDLSH

NLRC5

1601

Q86WI3
ELASRTRHLASVLDK

MCIDAS

226

D6RGH6
DDLAHELVTSKIALR

RABGAP1L

31

B7ZAP0
HAKDLALLDISESVL

NPAS4

221

Q8IUM7
SLAKAHERLEDSKLE

PALS2

36

Q9NZW5
LRAGETTHKILDLES

PDP2

86

Q9P2J9
STAIREISLLKELKH

CDK3

46

Q00526
SKIHAARSLSEIAID

FRMD4A

326

Q9P2Q2
HLREKEILDSSLPSS

DNAH1

786

Q9P2D7
LDKFLSHVISALVSE

HBQ1

126

P09105
DHAKVLTLSDDLERT

EIF5

221

P55010
RDSILSHKVLDEDSK

CARD6

341

Q9BX69
DDEVSRILASKLLHE

DOCK6

896

Q96HP0
AEELELSILKISHSL

CTNNAL1

376

Q9UBT7
ESLLANVASLRHELK

CCDC18

16

Q5T9S5
LSDELLLALSSEKHV

FBXL3

236

Q9UKT7
SDLVRDEKRLTLGHS

FAM83C

711

Q9BQN1
HSKESLDRTLDALSE

C19orf44

486

Q9H6X5
KLHQERDESTLATSL

FRMPD2

1261

Q68DX3
SAVLDLVHSAERLAL

CTU1

261

Q7Z7A3
KLRSSTELHPDLLTD

GLIS3

506

Q8NEA6
GERDHLITKRDLALS

ITGAV

881

P06756
LITKRDLALSEGDIH

ITGAV

886

P06756
RLEHLFESKSKELSV

FHOD3

931

Q2V2M9
EFTVSLHLARKLLSE

IL27

46

Q8NEV9
KSEILNSALDHALRT

AKNAD1

791

Q5T1N1
SALSIDETRAHLLLK

ADA2

26

Q9NZK5
VALRKTDHLSLDKAT

ASAP1

901

Q9ULH1
ILDALRKESSRHSKL

HES4

61

Q9HCC6
HDVELLSSLALARSA

MAN2C1

541

Q9NTJ4
DLSHTSLLENEKLIL

CEP192

191

Q8TEP8
ATDLDEPDTLHTRLK

DSC1

266

Q08554
LLVFTTDAKTHIALD

ITGB3

271

P05106
LSAHALSDLLSRLVE

FRY

1881

Q5TBA9
LHVKLSSESKRADTL

HOOK1

381

Q9UJC3
SKDSETHKALSDLEL

CYP3A7

281

P24462
SRAAEESLRSLAKHE

FHOD1

906

Q9Y613
LVHTRSLLKETLDIS

FIBIN

166

Q8TAL6
IHKNADDISSRLTLI

DNAH10

776

Q8IVF4
DALESAKRAVHLSDV

PEX11B

66

O96011
SVKLHLETDSLALVA

C4A

586

P0C0L4
SFRKHREDVLSLLET

FANCD2

1316

Q9BXW9
DLLRHTSGLSKLSLE

PRAMEF13

396

Q5VWM6
ALREKLFAHSSDLLS

PPEF2

561

O14830
VFLHVRTSIKDALDL

OR6F1

256

Q8NGZ6
HILAKERESALSLAS

RFXANK

151

O14593
TSLELAHLKDFVSAL

ABCC1

1401

P33527
LLHVDTRKRLSTIDE

SLITRK4

731

Q8IW52
RRHLKLSDKSATDEL

SKOR1

246

P84550
DTLDRTLGDKRHLVT

GFM2

576

Q969S9
LDVKILLDELSSTKH

PTAR1

211

Q7Z6K3
KELISADLEHSLAEL

SYNE1

4956

Q8NF91
RHIKELEKLLDVSSS

SYNE1

8651

Q8NF91
LHLKETDTATLRASL

SYNE2

5016

Q8WXH0
ITLSVKLEDALARAH

PRR5

156

P85299
EAAALLLEHRASLSA

PPP1R16A

246

Q96I34
ELKILRASAETLHSL

SETD4

421

Q9NVD3
EEDLRTKLLSLKLSH

TEKT2

301

Q9UIF3
LFSKSIETLRVHLAE

UBA2

321

Q9UBT2
ISLFDLEKDLHIIST

MYCBP2

511

O75592
IDALKDLLRHTSGLS

PRAMEF1

391

O95521
DLLRHTSGLSKLSLE

PRAMEF1

396

O95521
LRATAHALDTVLALE

PKHD1

2051

P08F94
ELEELSGAKISDLHR

IARS1

486

P41252
IDALKDLLRHTSGLS

PRAMEF2

391

O60811
DLLRHTSGLSKLSLE

PRAMEF2

396

O60811
SKEELSAELLHLSLN

SWT1

526

Q5T5J6
TLKRHEAAESELLAT

SPTBN5

1351

Q9NRC6
ELDPSHLLASRDISK

SMCR8

651

Q8TEV9
HLLASRDISKTSLDN

SMCR8

656

Q8TEV9
IHALLETEFSLKLLS

AKAP6

121

Q13023
SLELSSHLAKDLLVL

NCAPG

856

Q9BPX3
LLETLGDKDHSIRAL

CLASP1

1351

Q7Z460
DLSLDHSDLVAELLK

CLASP2

1051

O75122
DVSLKSSRLSQEHLD

ZBTB25

401

P24278
SSSDHLKDRLARDTL

PKP3

431

Q9Y446
YSLERSKSLLLEHLE

TRIML2

211

Q8N7C3
HAERALKLVSDTLAE

ZFR2

616

Q9UPR6
ELLNLRKISSDLDGH

TKT

96

P29401
AEVSTDHLKLFLSRR

SPEG

1861

Q15772
TRFLDTLLEELHLKN

RPAP2

581

Q8IXW5
IHSILLLVDKESAFR

PLEKHG4B

286

Q96PX9
EKLESIFKERSLSLH

TRPM3

1376

Q9HCF6
GDISESDLLNLRKLH

TKTL2

91

Q9H0I9
SDLLNLRKLHSDLER

TKTL2

96

Q9H0I9
FLLDESLESLKRIHE

UBE4B

1036

O95155
LSQASADLEATLRHK

TRIM25

191

Q14258
SLFLEESKVLHAREL

ZDBF2

2126

Q9HCK1
SVLDVRSLKDSLDHF

WDR53

76

Q7Z5U6
KSSTLILHRATLRDA

TRAV26-2

86

A0A0B4J265
FDALTELKVLRLHSN

TLR7

286

Q9NYK1
VLLDLSSHEKDKVRS

SYMPK

716

Q92797
RDLHSKNKDDLTLSR

MAP2

671

P11137
DKRFATSEELLSHLR

ZNF503

526

Q96F45
SLVLPHSTKERDSEL

UHRF1

76

Q96T88
TERALKLVSDSLSEH

ZFR

751

Q96KR1
SFADELSHLLTLVSK

ZMYM1

841

Q5SVZ6
LSRDLKDDFHSDTVL

ZBTB38

6

Q8NAP3
ERIEFAHKLLTLLNS

USP34

3026

Q70CQ2
LSLDLESRNETKHLS

ZNF529

76

Q6P280
RISEAHSELAKLLTE

TRIM23

486

P36406
SDHKAELSVLAALSL

PIGG

691

Q5H8A4
SKIAARHALLETALT

SFXN5

241

Q8TD22
ALDKLLSFTHKLRET

VWA8

631

A3KMH1
RLLDIEEAVHKALSS

XIRP1

1546

Q702N8
SLDSNHSLVLESLKR

WDR64

296

B1ANS9
HSLVLESLKRLEDNL

WDR64

301

B1ANS9
DLNKLLESTRRLHDE

ZC4H2

86

Q9NQZ6
ESSLLLIRDKDELIH

KLRB1

126

Q12918
KLLASDAEALSLLAH

LMF1

486

Q96S06
SLERLSFSHNKIEVL

LRRC8C

661

Q8TDW0
KEDIHSLALLTTDRL

LRRCC1

461

Q9C099
NILSLSLKHLEFTEE

N4BP2

621

Q86UW6
LLSSRSHLQELEKEL

PDE4DIP

1936

Q5VU43