Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	extracellular matrix constituent, lubricant activity	MUC3A MUC4	3.53e-05	4	49	2	GO:0030197
GeneOntologyCellularComponent	Golgi lumen	MUC19 MUC16 MUC12 MUC3A MUC4	5.58e-06	109	49	5	GO:0005796
GeneOntologyCellularComponent	histone acetyltransferase complex	EP400 ACTL9 TAF12 HCFC1	6.96e-05	94	49	4	GO:0000123
GeneOntologyCellularComponent	protein acetyltransferase complex	EP400 ACTL9 TAF12 HCFC1	1.03e-04	104	49	4	GO:0031248
GeneOntologyCellularComponent	acetyltransferase complex	EP400 ACTL9 TAF12 HCFC1	1.24e-04	109	49	4	GO:1902493
GeneOntologyCellularComponent	H4 histone acetyltransferase complex	EP400 ACTL9 HCFC1	1.60e-04	45	49	3	GO:1902562
GeneOntologyCellularComponent	SWI/SNF superfamily-type complex	SALL1 EP400 BCL7C	1.48e-03	96	49	3	GO:0070603
Domain	SEA	MUC16 MUC12 MUC3A	2.55e-05	23	47	3	PS50024
Domain	SEA_dom	MUC16 MUC12 MUC3A	2.55e-05	23	47	3	IPR000082
Domain	SEA	MUC16 MUC3A	5.53e-04	14	47	2	SM00200
Domain	VWD	MUC19 MUC4	7.27e-04	16	47	2	SM00216
Domain	VWF_type-D	MUC19 MUC4	7.27e-04	16	47	2	IPR001846
Domain	VWFD	MUC19 MUC4	7.27e-04	16	47	2	PS51233
Domain	VWD	MUC19 MUC4	7.27e-04	16	47	2	PF00094
Domain	SEA	MUC16 MUC12	1.39e-03	22	47	2	PF01390
Domain	EGF_1	TNC MUC12 MUC3A MUC4	3.82e-03	255	47	4	PS00022
Domain	EGF-like_CS	TNC MUC12 MUC3A MUC4	4.15e-03	261	47	4	IPR013032
Domain	EGF_2	TNC MUC12 MUC3A MUC4	4.38e-03	265	47	4	PS01186
Domain	FN3	TNC SDK1 HCFC1	1.13e-02	185	47	3	SM00060
Pathway	REACTOME_DEFECTIVE_GALNT3_CAUSES_HFTC	MUC16 MUC12 MUC3A MUC4	5.67e-08	16	35	4	M27410
Pathway	REACTOME_DEFECTIVE_C1GALT1C1_CAUSES_TNPS	MUC16 MUC12 MUC3A MUC4	7.40e-08	17	35	4	M27412
Pathway	REACTOME_TERMINATION_OF_O_GLYCAN_BIOSYNTHESIS	MUC16 MUC12 MUC3A MUC4	2.73e-07	23	35	4	M556
Pathway	REACTOME_DECTIN_2_FAMILY	MUC16 MUC12 MUC3A MUC4	4.58e-07	26	35	4	M27483
Pathway	REACTOME_DISEASES_ASSOCIATED_WITH_O_GLYCOSYLATION_OF_PROTEINS	ADAMTS12 MUC16 MUC12 MUC3A MUC4	6.53e-07	68	35	5	M27303
Pathway	REACTOME_O_LINKED_GLYCOSYLATION	ADAMTS12 MUC16 MUC12 MUC3A MUC4	7.43e-06	111	35	5	M27416
Pathway	REACTOME_O_LINKED_GLYCOSYLATION_OF_MUCINS	MUC16 MUC12 MUC3A MUC4	1.60e-05	62	35	4	M546
Pathway	REACTOME_TERMINATION_OF_O_GLYCAN_BIOSYNTHESIS	MUC19 MUC16 MUC4	1.81e-05	21	35	3	MM15706
Pathway	REACTOME_DISEASES_OF_GLYCOSYLATION	ADAMTS12 MUC16 MUC12 MUC3A MUC4	2.54e-05	143	35	5	M27275
Pathway	REACTOME_O_LINKED_GLYCOSYLATION	ADAMTS12 MUC19 MUC16 MUC4	1.47e-04	109	35	4	MM15164
Pathway	REACTOME_DISEASES_OF_METABOLISM	ADAMTS12 MUC16 MUC12 MUC3A MUC4	3.54e-04	250	35	5	M27554
Pathway	REACTOME_C_TYPE_LECTIN_RECEPTORS_CLRS	MUC16 MUC12 MUC3A MUC4	3.84e-04	140	35	4	M27484
Pathway	WP_MARKERS_OF_KIDNEY_CELL_LINEAGE	HNF1B SALL1 TNC	4.14e-04	59	35	3	M46460
Pathway	REACTOME_O_LINKED_GLYCOSYLATION_OF_MUCINS	MUC19 MUC16 MUC4	4.35e-04	60	35	3	MM15636
Pathway	REACTOME_ISG15_ANTIVIRAL_MECHANISM	FLNB NUP98 NUP214	8.05e-04	74	35	3	M48006
Pubmed	Mucin gene expression in human laryngeal epithelia: effect of laryngopharyngeal reflux.	MUC19 MUC16 MUC12 MUC3A MUC4	3.80e-11	18	49	5	18834073
Pubmed	Interaction network of human early embryonic transcription factors.	SALL1 TCF20 EP400 BCL7C NUP98 NUP214 ZHX2 TAF12 AHDC1	1.41e-09	351	49	9	38297188
Pubmed	Dynamic Protein Interactions of the Polycomb Repressive Complex 2 during Differentiation of Pluripotent Cells.	EP400 BCL7C NUP98 NUP214 MUC4 BAG6 AHDC1 HCFC1	2.86e-07	469	49	8	27634302
Pubmed	Human transcription factor protein interaction networks.	HNF1B SALL1 TCF20 EP400 BCL7C NUP98 GIGYF2 NUP214 ZHX2 TAF12 HCFC1 ZNF687	4.97e-07	1429	49	12	35140242
Pubmed	Comprehensive Interactome Mapping of the DNA Repair Scaffold SLX4 Using Proximity Labeling and Affinity Purification.	SALL1 TCF20 EP400 NCAPH2 HCFC1 ZNF687	7.03e-07	222	49	6	37071664
Pubmed	An improved smaller biotin ligase for BioID proximity labeling.	TCF20 NUP98 MUC19 NUP214 HCFC1	8.58e-07	123	49	5	26912792
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	TCF20 EP400 GIGYF2 NUP214 ZHX2 ARHGEF17 PLXNA2	1.61e-06	407	49	7	12693553
Pubmed	The PHLPP1 N-Terminal Extension Is a Mitotic Cdk1 Substrate and Controls an Interactome Switch.	FLNB MAP7D3 NUP98 GIGYF2 NUP214 HCFC1	1.61e-06	256	49	6	33397691
Pubmed	Immunocytochemistry for MUC4 and MUC16 is a useful adjunct in the diagnosis of pancreatic adenocarcinoma on fine-needle aspiration cytology.	MUC16 MUC4	1.94e-06	2	49	2	23544943
Pubmed	Proximity-dependent Mapping of the Androgen Receptor Identifies Kruppel-like Factor 4 as a Functional Partner.	CDK8 TCF20 EP400 BCL7C AHDC1 HCFC1	2.10e-06	268	49	6	33640491
Pubmed	Microbial products alter the expression of membrane-associated mucin and antimicrobial peptides in a three-dimensional human endocervical epithelial cell model.	MUC16 MUC4	5.83e-06	3	49	2	23053434
Pubmed	Nucleoporins nup98 and nup214 participate in nuclear export of human immunodeficiency virus type 1 Rev.	NUP98 NUP214	5.83e-06	3	49	2	9847314
Pubmed	Expression of mucin (MUC) genes in mucoepidermoid carcinoma.	MUC19 MUC4	5.83e-06	3	49	2	21072847
Pubmed	Integrative analysis of the cancer genome atlas and cancer cell lines encyclopedia large-scale genomic databases: MUC4/MUC16/MUC20 signature is associated with poor survival in human carcinomas.	MUC16 MUC4	5.83e-06	3	49	2	30236127
Pubmed	Genome-wide bidirectional CRISPR screens identify mucins as host factors modulating SARS-CoV-2 infection.	MUC16 MUC4	5.83e-06	3	49	2	35879412
Pubmed	Nup98 localizes to both nuclear and cytoplasmic sides of the nuclear pore and binds to two distinct nucleoporin subcomplexes.	NUP98 NUP214	5.83e-06	3	49	2	12589057
Pubmed	The nuclear pore complex: a new dynamic in HIV-1 replication.	NUP98 NUP214	5.83e-06	3	49	2	21327100
Pubmed	Regulation of membrane-associated mucins in the human corneal epithelial cells by dexamethasone.	MUC16 MUC4	5.83e-06	3	49	2	17592322
Pubmed	A role for nucleoporin FG repeat domains in export of human immunodeficiency virus type 1 Rev protein and RNA from the nucleus.	NUP98 NUP214	5.83e-06	3	49	2	8943370
Pubmed	Prevalence of mutations in renal developmental genes in children with renal hypodysplasia: results of the ESCAPE study.	HNF1B SALL1	5.83e-06	3	49	2	16971658
Pubmed	Functional Consequences of Differential O-glycosylation of MUC1, MUC4, and MUC16 (Downstream Effects on Signaling).	MUC16 MUC4	5.83e-06	3	49	2	27483328
Pubmed	MicroRNA-200c modulates the expression of MUC4 and MUC16 by directly targeting their coding sequences in human pancreatic cancer.	MUC16 MUC4	5.83e-06	3	49	2	24204560
Pubmed	Differential Expression of MUC12, MUC16, and MUC20 in Patients with Active and Remission Ulcerative Colitis.	MUC16 MUC12	5.83e-06	3	49	2	26770020
Pubmed	Expression of the transmembrane mucins, MUC1, MUC4 and MUC16, in normal endometrium and in endometriosis.	MUC16 MUC4	5.83e-06	3	49	2	24939955
Pubmed	FBXO22 promotes leukemogenesis by targeting BACH1 in MLL-rearranged acute myeloid leukemia.	UBA6 GIGYF2 NUP214 MUC4 BAG6 HCFC1 ZNF687	5.97e-06	497	49	7	36774506
Pubmed	H4K20me0 recognition by BRCA1-BARD1 directs homologous recombination to sister chromatids.	TCF20 MAP7D3 EP400 NUP98 NCAPH2 NUP214 TAF12 AHDC1 HCFC1 ZNF687	1.07e-05	1294	49	10	30804502
Pubmed	TRPV4 activation in human corneal epithelial cells promotes membrane mucin production.	MUC16 MUC4	1.16e-05	4	49	2	39024979
Pubmed	In vitro analysis of nuclear transport mediated by the C-terminal shuttle domain of Tap.	NUP98 NUP214	1.16e-05	4	49	2	11551912
Pubmed	The importin-beta family member Crm1p bridges the interaction between Rev and the nuclear pore complex during nuclear export.	NUP98 NUP214	1.16e-05	4	49	2	9368759
Pubmed	Biallelic mutations in nucleoporin NUP88 cause lethal fetal akinesia deformation sequence.	NUP98 NUP214	1.16e-05	4	49	2	30543681
Pubmed	Large-scale characterization of HeLa cell nuclear phosphoproteins.	TCF20 EP400 BCL7C NUP98 GIGYF2 NUP214 BAG6 ZNF687	1.17e-05	774	49	8	15302935
Pubmed	Oxidative stress inhibits nuclear protein export by multiple mechanisms that target FG nucleoporins and Crm1.	NUP98 NUP214	1.94e-05	5	49	2	19828735
Pubmed	Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.	FLNB SALL1 TCF20 GIGYF2 NUP214 ZNF687	2.63e-05	418	49	6	34709266
Pubmed	The activator-recruited cofactor/Mediator coactivator subunit ARC92 is a functionally important target of the VP16 transcriptional activator.	CDK8 HCFC1	2.91e-05	6	49	2	14983011
Pubmed	Karyopherin beta2 mediates nuclear import of a mRNA binding protein.	NUP98 NUP214	2.91e-05	6	49	2	9144189
Pubmed	Cessation of HIV-1 transcription by inhibiting regulatory protein Rev-mediated RNA transport.	NUP98 NUP214	2.91e-05	6	49	2	19149559
Pubmed	Expression of Muc19/Smgc gene products during murine sublingual gland development: cytodifferentiation and maturation of salivary mucous cells.	MUC19 MUC16	2.91e-05	6	49	2	19110483
Pubmed	Proteome-scale mapping of binding sites in the unstructured regions of the human proteome.	SALL1 EP400 NUP98 NUP214 ZNF804A FAM110B	3.08e-05	430	49	6	35044719
Pubmed	BioID identifies novel c-MYC interacting partners in cultured cells and xenograft tumors.	TCF20 EP400 TAF12 HCFC1	3.90e-05	134	49	4	25452129
Pubmed	Cofactor requirements for nuclear export of Rev response element (RRE)- and constitutive transport element (CTE)-containing retroviral RNAs. An unexpected role for actin.	NUP98 NUP214	4.07e-05	7	49	2	11238447
Pubmed	The Nse5/6-like SIMC1-SLF2 complex localizes SMC5/6 to viral replication centers.	SALL1 TCF20 MAP7D3 EP400 NUP98 GIGYF2 NUP214 HCFC1	5.18e-05	954	49	8	36373674
Pubmed	Imaging within single NPCs reveals NXF1's role in mRNA export on the cytoplasmic side of the pore.	NUP98 NUP214	5.42e-05	8	49	2	31375530
Pubmed	A human MAP kinase interactome.	TCF20 NUP98 KIAA1328 GIGYF2 NUP214 MUC12	6.07e-05	486	49	6	20936779
Pubmed	Cloning and characterization of human karyopherin beta3.	NUP98 NUP214	6.96e-05	9	49	2	9114010
Pubmed	Identifying biological pathways that underlie primordial short stature using network analysis.	FLNB TCF20 EP400 NUP98 UBA6 GIGYF2 NUP214 BAG6	8.49e-05	1024	49	8	24711643
Pubmed	Nuclear import of the glucocorticoid receptor-hsp90 complex through the nuclear pore complex is mediated by its interaction with Nup62 and importin beta.	NUP98 NUP214	8.69e-05	10	49	2	19581287
Pubmed	An Oct4-centered protein interaction network in embryonic stem cells.	CDK8 SALL1 EP400 HCFC1	9.18e-05	167	49	4	20362541
Pubmed	Identification of SUMO Binding Proteins Enriched after Covalent Photo-Cross-Linking.	FLNB EP400 NCAPH2 NUP214 HCFC1	1.04e-04	332	49	5	32786267
Pubmed	Mouse endothelial OTUD1 promotes angiotensin II-induced vascular remodeling by deubiquitinating SMAD3.	FLNB BAG6	1.06e-04	11	49	2	36579465
Pubmed	Quantitative proteomic profiling of the extracellular matrix of pancreatic islets during the angiogenic switch and insulinoma progression.	TNC MUC4 HCFC1 PLXNA2	1.10e-04	175	49	4	28071719
Pubmed	MYC Protein Interactome Profiling Reveals Functionally Distinct Regions that Cooperate to Drive Tumorigenesis.	EP400 MUC19 TAF12 HCFC1 ZNF687	1.15e-04	339	49	5	30415952
Pubmed	Mediator requirement for both recruitment and postrecruitment steps in transcription initiation.	CDK8 SRF	1.27e-04	12	49	2	15749018
Pubmed	Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst.	SOX3 SALL1 TCF20 SRF TAF12 PLXNA2 ZNF687	1.31e-04	808	49	7	20412781
Pubmed	Compartmentalization of the SUMO/RNF4 pathway by SLX4 drives DNA repair.	SALL1 EP400 NUP214 HCFC1 ZNF687	1.46e-04	357	49	5	37059091
Pubmed	Promoting anti-tumor immunity by targeting TMUB1 to modulate PD-L1 polyubiquitination and glycosylation.	FLNB GIGYF2 BAG6	1.46e-04	72	49	3	36376293
Pubmed	Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.	DNHD1 FLNB NUP98 UBA6 GIGYF2 NUP214 MYO18B BAG6 HCFC1	1.48e-04	1425	49	9	30948266
Pubmed	TAP (NXF1) belongs to a multigene family of putative RNA export factors with a conserved modular architecture.	NUP98 NUP214	1.75e-04	14	49	2	11073998
Pubmed	Oct4 links multiple epigenetic pathways to the pluripotency network.	FLNB SALL1 GIGYF2 HCFC1	1.94e-04	203	49	4	22083510
Pubmed	The variant Polycomb Repressor Complex 1 component PCGF1 interacts with a pluripotency sub-network that includes DPPA4, a regulator of embryogenesis.	SALL1 TCF20 EP400 MUC16 BAG6	2.36e-04	396	49	5	26687479
Pubmed	Identification and functional characterization of transcriptional activators in human cells.	SALL1 TCF20 EP400 SRF ZHX2	2.41e-04	398	49	5	35016035
Pubmed	The C-terminal domain of TAP interacts with the nuclear pore complex and promotes export of specific CTE-bearing RNA substrates.	NUP98 NUP214	2.61e-04	17	49	2	10668806
Pubmed	TNF-α inhibits glucocorticoid receptor-induced gene expression by reshaping the GR nuclear cofactor profile.	SALL1 TCF20 MAP7D3 TNC MUC16 ZNF687	2.66e-04	638	49	6	31182584
Pubmed	Transcription factor protein interactomes reveal genetic determinants in heart disease.	SALL1 MAP7D3 EP400 NUP98 HCFC1	2.80e-04	411	49	5	35182466
Pubmed	Proximity biotinylation and affinity purification are complementary approaches for the interactome mapping of chromatin-associated protein complexes.	CDK8 FLNB MAP7D3 EP400 BAG6 ZNF687	2.82e-04	645	49	6	25281560
Pubmed	Architectural niche organization by LHX2 is linked to hair follicle stem cell function.	FLNB TNC	2.93e-04	18	49	2	24012369
Pubmed	Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.	FLNB TCF20 NUP98 GIGYF2 NUP214 HCFC1	3.01e-04	653	49	6	22586326
Pubmed	Investigation of type 2 diabetes risk alleles support CDKN2A/B, CDKAL1, and TCF7L2 as susceptibility genes in a Han Chinese cohort.	HNF1B TCF20	3.27e-04	19	49	2	20161779
Pubmed	Genome-wide association study identifies 8 novel loci associated with blood pressure responses to interventions in Han Chinese.	SALL1 FAM110B	3.27e-04	19	49	2	24165912
Pubmed	USP7 targets XIAP for cancer progression: Establishment of a p53-independent therapeutic avenue for glioma.	DNHD1 FLNB GIGYF2 ARHGEF17	3.34e-04	234	49	4	36243803
Pubmed	Identification of proximal SUMO-dependent interactors using SUMO-ID.	SALL1 EP400 ZHX2 AHDC1 HCFC1	3.98e-04	444	49	5	34795231
Pubmed	Conserved and Divergent Molecular and Anatomic Features of Human and Mouse Nephron Patterning.	HNF1B SALL1	4.41e-04	22	49	2	29449451
Pubmed	Sall1 and Sall4 cooperatively interact with Myocd and SRF to promote cardiomyocyte proliferation by regulating CDK and cyclin genes.	SALL1 SRF	4.41e-04	22	49	2	38014633
Pubmed	Comparative Application of BioID and TurboID for Protein-Proximity Biotinylation.	HNF1B TCF20 NUP98 NUP214 AHDC1	4.54e-04	457	49	5	32344865
Pubmed	BioID-based intact cell interactome of the Kv1.3 potassium channel identifies a Kv1.3-STAT3-p53 cellular signaling pathway.	FLNB MAP7D3 UBA6 GIGYF2 NUP214 HCFC1	4.63e-04	708	49	6	39231216
Pubmed	cDNAs with long CAG trinucleotide repeats from human brain.	EP400 GIGYF2	4.83e-04	23	49	2	9225980
Pubmed	Defining the human deubiquitinating enzyme interaction landscape.	FLNB MARK1 NUP98 GIGYF2 NUP214 BAG6 HCFC1	4.91e-04	1005	49	7	19615732
Pubmed	Systematic mapping of genetic interactions for de novo fatty acid synthesis identifies C12orf49 as a regulator of lipid metabolism.	CDK8 SALL1 GIGYF2 NCAPH2 NUP214 MUC12 TUBGCP5 BAG6	4.93e-04	1327	49	8	32694731
Pubmed	Synthetic Lethal and Resistance Interactions with BET Bromodomain Inhibitors in Triple-Negative Breast Cancer.	TCF20 EP400 NUP98 UBA6 TAF12 HCFC1 ZNF687	5.18e-04	1014	49	7	32416067
Pubmed	Mitochondrial antiviral-signalling protein is a client of the BAG6 protein quality control complex.	BAG6 HCFC1	5.26e-04	24	49	2	35543156
Pubmed	Stromal Fat4 acts non-autonomously with Dchs1/2 to restrict the nephron progenitor pool.	SALL1 TNC	5.26e-04	24	49	2	26116661
Pubmed	Majority of cerebrospinal fluid-contacting neurons in the spinal cord of C57Bl/6N mice is present in ectopic position unlike in other studied experimental mice strains and mammalian species.	ADAMTS12 MYO18B	5.26e-04	24	49	2	32212159
Pubmed	The human CDK8 subcomplex is a molecular switch that controls Mediator coactivator function.	CDK8 TAF12	5.71e-04	25	49	2	19240132
Pubmed	P300 Interacted With N-Myc and Regulated Its Protein Stability via Altering Its Post-Translational Modifications in Neuroblastoma.	EP400 HCFC1	5.71e-04	25	49	2	36708875
Pubmed	Nuclear import of hepatic glucokinase depends upon glucokinase regulatory protein, whereas export is due to a nuclear export signal sequence in glucokinase.	NUP98 NUP214	5.71e-04	25	49	2	10601273
Pubmed	Docking of HIV-1 Vpr to the nuclear envelope is mediated by the interaction with the nucleoporin hCG1.	NUP98 NUP214	6.18e-04	26	49	2	12228227
Pubmed	Histone deacetylases 1 and 2 regulate the transcriptional programs of nephron progenitors and renal vesicles.	HNF1B SALL1	6.18e-04	26	49	2	29712641
Pubmed	Human ATAC Is a GCN5/PCAF-containing acetylase complex with a novel NC2-like histone fold module that interacts with the TATA-binding protein.	TAF12 HCFC1	6.67e-04	27	49	2	18838386
Pubmed	A promiscuous biotin ligase fusion protein identifies proximal and interacting proteins in mammalian cells.	NUP98 NUP214 HCFC1	6.73e-04	121	49	3	22412018
Pubmed	A probability-based approach for high-throughput protein phosphorylation analysis and site localization.	FLNB NUP98 BAG6 HCFC1 ZNF687	7.00e-04	503	49	5	16964243
Pubmed	Genome-wide analysis of chromosomal alterations in patients with esophageal squamous cell carcinoma exposed to tobacco and betel quid from high-risk area in India.	CDK8 TNC	8.25e-04	30	49	2	20083228
Pubmed	PRISMA and BioID disclose a motifs-based interactome of the intrinsically disordered transcription factor C/EBPα.	CDK8 TCF20 EP400 BAG6 AHDC1 HCFC1 ZNF687	8.50e-04	1103	49	7	34189442
Pubmed	Biological insights from 108 schizophrenia-associated genetic loci.	TCF20 GIGYF2 PRKD1 ZNF804A	8.79e-04	303	49	4	25056061
Pubmed	Microarray analysis of the Df1 mouse model of the 22q11 deletion syndrome.	SOX3 TCF20	8.81e-04	31	49	2	15778864
Pubmed	Wnt/β-catenin and Bmp signals control distinct sets of transcription factors in cardiac progenitor cells.	TNC SRF	8.81e-04	31	49	2	22711842
Pubmed	BTB-ZF factors recruit the E3 ligase cullin 3 to regulate lymphoid effector programs.	NUP98 NUP214	8.81e-04	31	49	2	23086144
Pubmed	NFIA controls telencephalic progenitor cell differentiation through repression of the Notch effector Hes1.	SOX3 TNC	9.39e-04	32	49	2	20610746
Pubmed	SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.	TCF20 MAP7D3 EP400 GIGYF2 HCFC1	1.04e-03	549	49	5	38280479
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	CDK8 FLNB KIAA1328 SRF UBA6 PRKD1 ZHX2 AHDC1	1.04e-03	1489	49	8	28611215
Pubmed	Nuclear pore composition regulates neural stem/progenitor cell differentiation in the mouse embryo.	NUP98 NUP214	1.06e-03	34	49	2	18539113
Pubmed	Analysis of genes from inner ear developmental-stage cDNA subtraction reveals molecular regionalization of the otic capsule.	FLNB TNC	1.12e-03	35	49	2	15031101
Interaction	CRX interactions	SOX3 HNF1B SALL1 TCF20 EP400 BCL7C ZHX2	2.20e-06	254	48	7	int:CRX
Interaction	NUP43 interactions	TCF20 EP400 NUP98 MUC19 NUP214 ZHX2 AHDC1 HCFC1 ZNF687	1.42e-05	625	48	9	int:NUP43
Interaction	NFIX interactions	SALL1 EP400 BCL7C SRF ZHX2 TAF12	1.58e-05	227	48	6	int:NFIX
Interaction	HDAC1 interactions	FLNB HNF1B SALL1 TCF20 EP400 NUP98 GIGYF2 NUP214 ZHX2 HCFC1 ZNF687	4.55e-05	1108	48	11	int:HDAC1
Interaction	POU5F1 interactions	FLNB SALL1 TCF20 EP400 MUC16 GIGYF2 BAG6 HCFC1	6.43e-05	584	48	8	int:POU5F1
Interaction	CLEC11A interactions	TCF20 NUP98 NUP214 AHDC1	8.01e-05	96	48	4	int:CLEC11A
Interaction	SUZ12 interactions	CDK8 FLNB EP400 NUP214 MUC4 BAG6 AHDC1 HCFC1	1.27e-04	644	48	8	int:SUZ12
Interaction	PHLPP1 interactions	FLNB MAP7D3 NUP98 GIGYF2 NUP214 HCFC1	1.33e-04	333	48	6	int:PHLPP1
GeneFamily	CD molecules\|Mucins	MUC19 MUC16 MUC12 MUC3A MUC4	2.50e-10	21	32	5	648
GeneFamily	Ataxins\|Trinucleotide repeat containing	EP400 GIGYF2	8.88e-04	25	32	2	775
GeneFamily	Nucleoporins	NUP98 NUP214	1.46e-03	32	32	2	1051
Coexpression	NABA_ECM_AFFILIATED	MUC19 MUC16 MUC12 MUC3A MUC4 PLXNA2	6.67e-07	170	48	6	M5880
Coexpression	GINESTIER_BREAST_CANCER_20Q13_AMPLIFICATION_DN	DNHD1 NUP214 BAG6 HCFC1 GRAMD4	2.16e-05	184	48	5	M19988
ToppCell	primary_visual_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Rspo4_Rxfp1_Chat\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	SOX3 HNF1B SALL1 ZNF804A SDK1	7.67e-07	155	49	5	3b8def9e8f66511736ea37f259511f7c8b7743af
ToppCell	3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.2.2\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	TNC SH3RF2 MUC16 MUC3A MUC4	1.36e-06	174	49	5	207aa0118633cbe9a65839bbb1bb3ba9f8118ad2
ToppCell	frontal_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Gpc3_Slc18a3\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	SOX3 HNF1B SALL1 ZNF804A	1.57e-05	137	49	4	d346086f42d8f04d3fa67fe696834284acdc7080
ToppCell	frontal_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Rspo4_Rxfp1_Chat\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	SOX3 HNF1B SALL1 SDK1	1.96e-05	145	49	4	78f5f4b96420c7f391e4d32a9ed151ed95fad90b
ToppCell	frontal_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Lmo1_Fam159b\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	SOX3 SALL1 ZNF804A SDK1	2.12e-05	148	49	4	9205b26e0d042b342cc643cda0f4f3f8bb392d00
ToppCell	frontal_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Ptprt_Pkp2\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	HNF1B SALL1 ZNF804A SDK1	3.65e-05	170	49	4	14aa86a4f526ed6986afcb28c49225522055550c
ToppCell	primary_visual_cortex-Neuronal-GABAergic_neuron-Vip\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	SOX3 SALL1 ZNF804A SDK1	3.82e-05	172	49	4	7e1a7700a4c2b1d100da1d6e475e73498ebb605a
ToppCell	Children_(3_yrs)-Epithelial-lung_goblet_cell-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	FLNB MUC16 MUC4 SDK1	3.91e-05	173	49	4	464267a2ff3f5c387b6c9c6fa4dab135a221f448
ToppCell	primary_visual_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Ptprt_Pkp2\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	HNF1B SALL1 ZNF804A SDK1	4.18e-05	176	49	4	05ec715439f2eb1696f5d8855da0dd1dd70effd0
ToppCell	5'-Adult-Appendix-Mesenchymal-fibroblastic-Stromal_2_(NPY+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ADAMTS12 TNC ARHGEF17 SDK1	4.46e-05	179	49	4	a1ea8daa0fe8900f5a04b555c77fe8ebdaa3908d
ToppCell	COVID-19-Heart-Pericyte\|COVID-19 / Disease (COVID-19 only), tissue and cell type	ADAMTS12 MARK1 ARHGEF17 MUC3A	4.66e-05	181	49	4	33cac65ed1ea5e7bd72250495df4f850b143d5aa
ToppCell	Children_(3_yrs)-Epithelial-lung_goblet_cell\|Children_(3_yrs) / Lineage, Cell type, age group and donor	FLNB MUC16 MUC4 SDK1	4.76e-05	182	49	4	3f1a666fe27dd7529c114539ed5f6b8ca585c875
ToppCell	RA-13._Vascular_Smooth_Muscle\|World / Chamber and Cluster_Paper	FLNB TNC PRKD1 SDK1	4.86e-05	183	49	4	cae2ee08f985a6f005b4b8e959e465350315156a
ToppCell	Fetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_1-D088\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	HNF1B SH3RF2 MUC4 PLXNA2	5.40e-05	188	49	4	43a3a59f92ad93509d4166bd025aed0b1b39a008
ToppCell	LA-13._Vascular_Smooth_Muscle\|LA / Chamber and Cluster_Paper	FLNB TNC PRKD1 SDK1	5.40e-05	188	49	4	34e1b074a3995aa46ab194eb45115d76d1a5514d
ToppCell	LA-13._Vascular_Smooth_Muscle\|World / Chamber and Cluster_Paper	FLNB TNC PRKD1 SDK1	5.51e-05	189	49	4	6b3e88751b95fc2173f2c3d5061ed632d0c5f01c
ToppCell	LPS-antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-Diff_MatrixFB\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ADAMTS12 TNC PRKD1 SDK1	5.51e-05	189	49	4	a153b83314cf52808f685296cff8c95af3f4983d
ToppCell	LPS-IL1RA+antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-Diff_MatrixFB\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ADAMTS12 TNC PRKD1 SDK1	5.63e-05	190	49	4	841cd55861b43578d704418b9bc0af2e8b88323a
ToppCell	LPS_only-Stromal_mesenchymal-Matrix_Fibroblast-Diff_MatrixFB\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ADAMTS12 TNC PRKD1 SDK1	5.63e-05	190	49	4	d60395739458d7f47a3350ade751fe3819500320
ToppCell	LPS-IL1RA+antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-Activated_MatrixFB\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ADAMTS12 TNC PRKD1 SDK1	5.74e-05	191	49	4	b13229bb7f3713a392271aaf5dbae3edd1b9fe5a
ToppCell	COVID-19-kidney-Mito-rich_Distal\|COVID-19 / Disease (COVID-19 only), tissue and cell type	HNF1B SALL1 CLCNKB PRKD1	5.74e-05	191	49	4	0965f621ebcd92ccdeb21cc27022180ce3cfe910
ToppCell	LPS-antiTNF-Stromal_mesenchymal-Matrix_Fibroblast\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ADAMTS12 TNC PRKD1 SDK1	5.86e-05	192	49	4	dcd924d6eb67d33ee9f5d3e8ab6e1d4283d6b708
ToppCell	LPS-IL1RA+antiTNF-Stromal_mesenchymal-Matrix_Fibroblast\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ADAMTS12 TNC PRKD1 SDK1	5.86e-05	192	49	4	6f4ef24dab544681304b7f8a9dc073e7edaa4cf5
ToppCell	LPS-IL1RA+antiTNF-Stromal_mesenchymal\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ADAMTS12 TNC PRKD1 SDK1	5.86e-05	192	49	4	3d0cb19f037f604253d7d728689aeaa94251e92b
ToppCell	LPS-IL1RA-Stromal_mesenchymal-Matrix_Fibroblast-MatrixFB\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ADAMTS12 TNC PRKD1 SDK1	5.86e-05	192	49	4	deeecd26972241846b4cb998edf0c7a87ff0c4df
ToppCell	LPS-IL1RA+antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-MatrixFB\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ADAMTS12 TNC PRKD1 SDK1	5.98e-05	193	49	4	fb28717fadd06c3840636d25409ce80c9254bd34
ToppCell	Control-Stromal-Myofibroblast\|Stromal / Disease state, Lineage and Cell class	ADAMTS12 TNC PRKD1 PLXNA2	5.98e-05	193	49	4	5896242f713ae5fd1a4ebb63827f15d7279dced2
ToppCell	LPS-antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-MatrixFB\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ADAMTS12 TNC PRKD1 SDK1	6.10e-05	194	49	4	60622bd2f75bfe4c37f721cb12f03dab33f2f58d
ToppCell	Control-Stromal-Myofibroblast\|World / Disease state, Lineage and Cell class	ADAMTS12 TNC PRKD1 SDK1	6.10e-05	194	49	4	3c2266772c5b56e8e02a461e5193e29588028ee9
ToppCell	LPS-antiTNF-Stromal_mesenchymal\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ADAMTS12 TNC PRKD1 SDK1	6.10e-05	194	49	4	6e13549f697f7478b34fe71f7dd9d63c5d3db22e
ToppCell	LPS-antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-Activated_MatrixFB\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ADAMTS12 TNC PRKD1 SDK1	6.10e-05	194	49	4	89b706af2b25991fc2707eb24f49ba6ff3ae01f7
ToppCell	Control-Stromal-Myofibroblast\|Control / Disease state, Lineage and Cell class	ADAMTS12 TNC PRKD1 SDK1	6.22e-05	195	49	4	ffcf76cd72e43d8cf1058a49c76e0956065038bc
ToppCell	Bronchial-NucSeq\|Bronchial / Cell types per location group and 10X technology with lineage, and cell group designations	KIAA1328 PRKD1 ZHX2 SDK1	6.35e-05	196	49	4	ab53c742866945545a92e2e61850d63c80d9a2a6
ToppCell	COVID-19-Fibroblasts-Intermediate_pathological_FB\|COVID-19 / group, cell type (main and fine annotations)	ADAMTS12 TNC PRKD1 SDK1	6.47e-05	197	49	4	f1c8936986123a3151140c374fcd62d6705c530b
ToppCell	Bronchus_Control_(B.)\|World / Sample group, Lineage and Cell type	TNC SH3RF2 MUC16 MUC4	6.47e-05	197	49	4	b6dff2ee108813e18657e2d8cf850e2423f8c8e9
ToppCell	3'-Broncho-tracheal-Epithelial-Airway_epithelium-respiratory_basal_cell-Suprabasal-Suprabasal_L.0.0.1.2\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	TNC MUC16 MUC4 SDK1	6.60e-05	198	49	4	9718f4c013c347f1b3c785ae232dd2fb6c1fe298
ToppCell	LPS_anti-TNF-Mesenchymal_fibroblastic-Fibroblasts-MatrixFB\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	ADAMTS12 TNC PRKD1 SDK1	6.86e-05	200	49	4	9b0916d8d07ac2bf1739f7be5296bf77ffee6094
ToppCell	Parenchymal-NucSeq-Epithelial-Epi_submucosal-gland-SMG_Duct\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	FLNB MUC16 MUC4 SDK1	6.86e-05	200	49	4	b992eeddee38e6fe3564e9b1850f6b20b89bf47d
ToppCell	Bronchial-NucSeq-Epithelial-Epi_airway_basal\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	MARK1 SH3RF2 MUC4 SDK1	6.86e-05	200	49	4	8827653738a931e4a4545e0c7d75be12bed40740
ToppCell	Thalamus-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)-Slc17a6-Rora-Excitatory_Neuron.Slc17a6.Rora.Cacng4_(Non-anterior_nuclei)\|Thalamus / BrainAtlas - Mouse McCarroll V32	SOX3 TNC ACTL9	8.07e-05	76	49	3	4afc8d0e79870c635a89dd8e7ca91ebfe482b4ab
ToppCell	primary_visual_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Igfbp4_Mab21l1\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	SALL1 ZNF804A SDK1	4.50e-04	136	49	3	9cf076597e6fd9390850fda259daa13022f15893
ToppCell	PND07-28-samps-Mesenchymal-Mesenchymal_stem_cell\|PND07-28-samps / Age Group, Lineage, Cell class and subclass	MYO18B AHDC1 FAM110B	4.59e-04	137	49	3	ed81624b9167255ce88dcf6ad7f1636376ea0525
ToppCell	PND07-28-samps-Mesenchymal-Mesenchymal_stem_cell-Mesenchymal_fibroblast\|PND07-28-samps / Age Group, Lineage, Cell class and subclass	MYO18B AHDC1 FAM110B	4.59e-04	137	49	3	47859aa25f32367461c1ec75ed9060bee430c6b7
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Degenerative_Inner_Medullary_Collecting_Duct_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	PINLYP SH3RF2 MYO18B	5.42e-04	145	49	3	6f6e08b1234a08f94bd17c11d267f39eabb10068
ToppCell	Fetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)-D088\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	SH3RF2 MUC4 PLXNA2	5.75e-04	148	49	3	9fe3c0a5904b8e9a0f28130f8d84d4f2a819b06c
ToppCell	frontal_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Arhgap36_Hmcn1\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	SOX3 SALL1 ZNF804A	6.33e-04	153	49	3	9c6fce56300ba5053efda59a438d63a808c497c0
ToppCell	facs-Skin-nan-24m-Epithelial-inner_bulge\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADAMTS12 FLNB PLXNA2	6.58e-04	155	49	3	fa2776d258e0420b2895de1008e292ad7725dac0
ToppCell	E16.5-samps-Mesenchymal-Myofibroblast-Migrating_MyoFibroblast\|E16.5-samps / Age Group, Lineage, Cell class and subclass	TNC MARK1 PLXNA2	6.58e-04	155	49	3	1882fa5fd25f77d6e3ac47b613f6fb3c67d8e50c
ToppCell	facs-Liver-Non-hepatocytes-3m-Endothelial-nan\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CACNA1B MUC4 ZNF804A	6.58e-04	155	49	3	8fdda4e3657ac56188ae88ed3caf145f4d9d1567
ToppCell	primary_visual_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Lect1_Oxtr\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	HNF1B SALL1 ZNF804A	6.58e-04	155	49	3	99e749f7075e2c64e9a0bf91009f95b6969197c8
ToppCell	3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.2.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	MUC16 MUC4 SDK1	7.08e-04	159	49	3	60b1f4dce2ce0911160fda17f137c064da31e2eb
ToppCell	TCGA-Stomach-Primary_Tumor-Stomach_Adenocarcinoma-Stomach_Adenocarcinoma_-_Tubular-6\|TCGA-Stomach / Sample_Type by Project: Shred V9	FLNB MUC4 HCFC1	7.08e-04	159	49	3	655c0749c238bd68cb797adb83e25a23b8a3cc9d
ToppCell	Children_(3_yrs)-Epithelial-lung_goblet_cell-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	MUC16 MUC4 SDK1	7.34e-04	161	49	3	2d63b279d9a5132e1c09b03930bf9039036d24a2
ToppCell	metastatic_Brain-T/NK_cells-Cytotoxic_CD8+_T\|T/NK_cells / Location, Cell class and cell subclass	HNF1B SH3RF2 MUC16	7.34e-04	161	49	3	e6e294b4ba911c1327664f1a0f93207096c6de03
ToppCell	primary_visual_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Gpc3_Slc18a3\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	SOX3 SALL1 ZNF804A	7.61e-04	163	49	3	ec9a20cfe0d69430f9c68cddd1ab0e4a3e4554b8
ToppCell	Adult-Epithelial-lung_goblet_cell-D175\|Adult / Lineage, Cell type, age group and donor	MARK1 MUC16 MUC4	7.75e-04	164	49	3	6e6aedb61f8e195d52e028fdda750a29bb14e57e
ToppCell	NS-control-d_0-4-Epithelial-Ionocyte\|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	SALL1 CLCNKB FAM110B	8.02e-04	166	49	3	6d9fb239f69ba519844f593c00d515e1aac4ff50
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c03-GZMK\|Severe-critical_progression_d12-22 / Compartment, severity and other cell annotations on 10x 3' data (130k)	UBA6 TAF12 ZNF687	8.02e-04	166	49	3	9e916fc1858573358e1eb5e3789b2c9f8ef74476
ToppCell	facs-Skin-Anagen-24m-Epithelial-bulge_keratinocyte\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FLNB TNC MUC19	8.16e-04	167	49	3	78909f685ccd1321064eb0887caf9263e0e54879
ToppCell	5'-GW_trimst-1.5-LargeIntestine-Epithelial-epithelial_progenitor_cell-Distal_progenitor\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	HNF1B SH3RF2 MUC16	8.16e-04	167	49	3	720dc5855c856b478b5ca90156b30bfcc5518d60
ToppCell	primary_visual_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Pygm_C1ql1\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	SALL1 ZNF804A SDK1	8.31e-04	168	49	3	f3879a8e11eaf866f37c52e67021be43f0b8784a
ToppCell	P28-Epithelial-airway_epithelial_cell-ciliated_cell_of_airway\|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	DNHD1 ARHGEF17 SDK1	8.31e-04	168	49	3	8c8dbdbc7053f34e4ca0c5067af502fbea109fc1
ToppCell	NS-critical-d_16-33-Epithelial-Ionocyte\|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	CLCNKB MUC19 FAM110B	8.31e-04	168	49	3	6a233045638cb83dab64789b996b7598c325001e
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	ADAMTS12 TNC SRF	8.59e-04	170	49	3	fa753cc8fbd04e63c9a303da4dc17ee2ce907f92
ToppCell	BL-critical-LOC-Epithelial-Ionocyte\|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	CLCNKB MUC19 PRKD1	8.59e-04	170	49	3	b465df2dac6b4e98b4ede6ad0c6347656757885c
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	ADAMTS12 TNC SRF	8.59e-04	170	49	3	03044e1436443b28dd39d5ef4fdb25c18e3a7546
ToppCell	15-Airway-Epithelial-Club-like_secretory\|Airway / Age, Tissue, Lineage and Cell class	SH3RF2 MUC16 MUC4	8.59e-04	170	49	3	1418031cc4b4a87a48621eb53a3c819cd713ddd0
ToppCell	facs-Lung-nan-3m-Endothelial-vein_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRKD1 TUBGCP5 PLXNA2	8.59e-04	170	49	3	67d7e1da3ebd2d14cb2e67799e94d655027ed5c4
ToppCell	facs-Lung-nan-3m-Endothelial-Vein_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRKD1 TUBGCP5 PLXNA2	8.59e-04	170	49	3	8e1f757ed62218c0fb6525f49d142dd2cd29acf9
ToppCell	5'-Airway_Nasal-Epithelial-Airway_epithelium-respiratory_basal_cell-Suprabasal-\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	PINLYP TNC MARK1	8.74e-04	171	49	3	121e63ca281ad765d76c2afb3b4d441329b47f81
ToppCell	5'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.0.4\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	MARK1 MUC16 MUC4	9.04e-04	173	49	3	176b956e71d98e8275d698b39437fc326e5fe449
ToppCell	facs-Lung-Endomucin_-18m-Myeloid-non-classical_monocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SPN GIGYF2 GRAMD4	9.04e-04	173	49	3	c31076c725f4cd912c56903592a2d9356ae59f54
ToppCell	facs-Lung-Endomucin_-18m-Myeloid-Nonclassical_Monocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SPN GIGYF2 GRAMD4	9.04e-04	173	49	3	a4ed191cfdf6588b7f3672995bf0a4fe9e4b8df6
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_1-Inh_L1-5_VIP_KCNJ2\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	SALL1 ZNF804A SDK1	9.19e-04	174	49	3	8d8cf8ad17dcc364f867e36b10834a21c0e36ad2
ToppCell	PND10-Epithelial-Epithelial_Airway-Basal-Basal-Basal_mature\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PINLYP SH3RF2 MUC4	9.19e-04	174	49	3	97d4a40b536a67fa52f055eab26106d041bf3220
ToppCell	PND10-Epithelial-Epithelial_Airway-Basal-Basal\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PINLYP SH3RF2 MUC4	9.19e-04	174	49	3	f9f399244c7d12caf8118ec3117d477a39e35c3b
ToppCell	PND10-Epithelial-Epithelial_Airway-Basal\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PINLYP SH3RF2 MUC4	9.19e-04	174	49	3	e8440eea7c81864defa57c89e9b569ad8033e5c5
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2-Inh_L3-6_VIP_KCTD13\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	SALL1 ZNF804A SDK1	9.19e-04	174	49	3	62f5dc7086e1491fc90f005ccadfa1b772b52fad
ToppCell	5'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-club_cell-Club_(non-nasal)\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	BCL7C MUC16 MUC4	9.19e-04	174	49	3	42f2ba54b4ea4c62482582b0ccdadffae0a5eb4a
ToppCell	Somatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_2\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ZNF804A SDK1 FAM110B	9.34e-04	175	49	3	11f49f00e000cbc137e3540a6d6805cde21d96e6
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2-Inh_L1-3_VIP_ZNF322P1\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	SALL1 ZNF804A SDK1	9.34e-04	175	49	3	9d09636a103daa8f622c3dbfd1f1536aaec3b6bb
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2-Inh_L3_VIP_CBLN1\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	SALL1 ZNF804A SDK1	9.34e-04	175	49	3	5a9160a9d05e01d945e77fd81bb0bd87139545cd
ToppCell	wk_15-18-Epithelial-Proximal_epithelial-Proximal_secretory_3\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	SH3RF2 MUC16 MUC4	9.50e-04	176	49	3	8d9d0fb46c418b2067be58aec822e8c2b1561461
ToppCell	5'-Adult-Distal_Rectal-Epithelial-goblet-Goblet_cell\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SH3RF2 SPATA20 MUC12	9.66e-04	177	49	3	e1e45956887371b1c18f1eb479dd930031497520
ToppCell	3'-Child09-12-SmallIntestine-Mesenchymal-fibroblastic-Stromal_4_(MMP1+)\|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SALL1 ZNF804A SDK1	9.66e-04	177	49	3	ac90e4ce5be304a5a7473736397327010f2d1999
ToppCell	cellseq2-Mesenchymal-Fibroblastic-Fibroblastic_2-ASMC\|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	SOX3 MYO18B ZNF804A	9.81e-04	178	49	3	8ec2a25dda96c9cc9c2904b6cb18f75a293f4969
ToppCell	cellseq2-Mesenchymal-Fibroblastic-Fibroblastic_2\|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	SOX3 MYO18B ZNF804A	9.81e-04	178	49	3	6c91331196696e0cf239d105f458e3230659fa38
ToppCell	390C-Epithelial_cells-Epithelial-G_(Club-Clara_cells)\|390C / Donor, Lineage, Cell class and subclass (all cells)	CACNA1B MUC16 MUC4	9.81e-04	178	49	3	fce60ce6b662f1bdaa3b4da43800c6c22fe89533
ToppCell	390C-Epithelial_cells-Epithelial-G_(Club-Clara_cells)-\|390C / Donor, Lineage, Cell class and subclass (all cells)	CACNA1B MUC16 MUC4	9.81e-04	178	49	3	b19c906e067b07eadfd68934d9330b447e24c708
ToppCell	3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.0.5\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	UBA6 MUC16 MUC4	9.97e-04	179	49	3	6e965e424eebef50f0202cff75f458be395cfca1
ToppCell	nucseq-Epithelial-Epithelial_Glandular\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	MUC16 MUC3A MUC4	9.97e-04	179	49	3	859cd8ee414ad6207c046ada2e655e49322dd01c
ToppCell	droplet-Kidney-nan-21m-Epithelial-Epcam____podocyte\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TNC MARK1 MUC4	1.01e-03	180	49	3	6327c938a4f99df9fee714e44f15ea4a4a63ae15
ToppCell	nucseq-Epithelial-Epithelial_Glandular-Goblet\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	MUC16 MUC3A MUC4	1.01e-03	180	49	3	3dc80bc636bf0e6ffc9762853132a9fe59fd1f66
ToppCell	nucseq-Epithelial-Epithelial_Glandular-Goblet-Goblet\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	MUC16 MUC3A MUC4	1.01e-03	180	49	3	668a2d8e1d5a390309d5eb62c836f5903144bea9
ToppCell	Pericytes-SSc-ILD_01\|World / lung cells shred on cell class, cell subclass, sample id	ADAMTS12 FLNB MARK1	1.03e-03	181	49	3	35c470988a93381eefa300831aabb813fa1b90bd
ToppCell	COPD-Epithelial-Basal\|World / Disease state, Lineage and Cell class	MARK1 MUC4 SDK1	1.03e-03	181	49	3	6d8a886b4afe729f8a05b9c0f4ea9375de735da4
ToppCell	Somatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2-Inh_L1-3_VIP_ZNF322P1\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	SALL1 ZNF804A SDK1	1.03e-03	181	49	3	062f00736eed96e4f4327615d093558dd7d82b20
ToppCell	facs-Lung-18m-Epithelial-airway_epithelial-club_cell\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	HNF1B PINLYP SH3RF2	1.03e-03	181	49	3	4a0f1b121570430afb100c589657d931184e124f
ToppCell	facs-Lung-18m-Epithelial-airway_epithelial-club_cell-club_cell\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	HNF1B PINLYP SH3RF2	1.03e-03	181	49	3	34b49092f71128898af3b311170c4ed8adfefcff
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2-Inh_L1-3_VIP_ZNF322P1\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	SALL1 ZNF804A SDK1	1.05e-03	182	49	3	d3a037268f026eb2f84428b1821022503cef7756
Drug	cellobiitol	SPN MUC12 MUC3A MUC4	1.19e-06	37	49	4	CID000003871
Drug	LY 294002; Down 200; 10uM; PC3; HT_HG-U133A	HNF1B EP400 SPN ZHX2 HCFC1 GRAMD4	3.54e-06	193	49	6	1236_DN
Drug	Gastrin tetrapeptide	FLNB SPN MUC12 MUC3A	4.05e-06	50	49	4	CID000005415
Drug	Tn epitope	SPN TNC MUC3A MUC4	5.96e-06	55	49	4	CID000447272
Drug	mucic acid	SPN PRKD1 MUC12 MUC3A	3.87e-05	88	49	4	CID000000607
Drug	rioprostil	SPN MUC12 MUC3A	4.45e-05	32	49	3	CID005311413
Drug	Nabumetone [42924-53-8]; Down 200; 17.6uM; MCF7; HT_HG-U133A	NCAPH2 ARHGEF17 TUBGCP5 AHDC1 GRAMD4	6.15e-05	195	49	5	5428_DN
Drug	Tranexamic acid [1197-18-8]; Down 200; 25.4uM; HL60; HG-U133A	MAP7D3 SPN SPATA20 NCAPH2 HCFC1	6.15e-05	195	49	5	1401_DN
Drug	Telenzepine dihydrochloride [147416-96-4]; Down 200; 9uM; HL60; HT_HG-U133A	FLNB NCAPH2 ZHX2 TUBGCP5 AHDC1	6.30e-05	196	49	5	2388_DN
Drug	Gliquidone [33342-05-1]; Down 200; 7.6uM; PC3; HT_HG-U133A	HNF1B TNC ZHX2 ZNF804A HCFC1	6.45e-05	197	49	5	7301_DN
Drug	Spironolactone [52-01-7]; Up 200; 9.6uM; HL60; HG-U133A	FLNB BCL7C SRF TAF12 ZNF804A	6.61e-05	198	49	5	1380_UP
Drug	Pindolol [13523-86-9]; Up 200; 16.2uM; HL60; HG-U133A	CDK8 ADAMTS12 HNF1B BCL7C TAF12	6.61e-05	198	49	5	1392_UP
Drug	Alfaxalone [23930-19-0]; Down 200; 12uM; MCF7; HT_HG-U133A	NCAPH2 ARHGEF17 ZNF804A AHDC1 FAM110B	6.61e-05	198	49	5	5451_DN
Drug	Tolfenamic acid [13710-19-5]; Up 200; 15.2uM; PC3; HT_HG-U133A	HNF1B SPN NCAPH2 NUP214 ARHGEF17	6.77e-05	199	49	5	2120_UP
Drug	Neomycin sulfate [1405-10-3]; Down 200; 4.2uM; HL60; HG-U133A	FLNB EP400 SPN SPATA20 NCAPH2	6.77e-05	199	49	5	1383_DN
Drug	Guanabenz acetate [23256-50-0]; Down 200; 13.8uM; HL60; HG-U133A	SPN BCL7C NUP98 SRF TAF12	6.77e-05	199	49	5	2045_DN
Drug	Atropine sulfate monohydrate [5908-99-6]; Up 200; 5.8uM; HL60; HG-U133A	ADAMTS12 EP400 SPN NCAPH2 TAF12	6.77e-05	199	49	5	1768_UP
Drug	Ozagrel hydrochloride [78712-43-3]; Down 200; 15.2uM; PC3; HT_HG-U133A	HNF1B SPN TNC ZHX2 PLXNA2	6.77e-05	199	49	5	7281_DN
Drug	radicicol	CACNA1B HNF1B SRF ZHX2 HCFC1	7.44e-05	203	49	5	CID000005033
Disease	Developmental regression	CACNA1B NUP214	5.64e-05	7	49	2	C1836830
Disease	Papillary Renal Cell Carcinoma	DNHD1 HNF1B MUC4 ZNF804A	6.15e-05	128	49	4	C1306837
Disease	Renal Cell Carcinoma	DNHD1 HNF1B MUC4 ZNF804A	6.15e-05	128	49	4	C0007134
Disease	Sarcomatoid Renal Cell Carcinoma	DNHD1 HNF1B MUC4 ZNF804A	6.15e-05	128	49	4	C1266043
Disease	Chromophobe Renal Cell Carcinoma	DNHD1 HNF1B MUC4 ZNF804A	6.15e-05	128	49	4	C1266042
Disease	Collecting Duct Carcinoma of the Kidney	DNHD1 HNF1B MUC4 ZNF804A	6.15e-05	128	49	4	C1266044
Disease	phenol sulfate measurement	PRKD1 MYO18B	7.52e-05	8	49	2	EFO_0021011
Disease	Conventional (Clear Cell) Renal Cell Carcinoma	DNHD1 HNF1B MUC4 ZNF804A	1.08e-04	148	49	4	C0279702
Disease	cholangiocarcinoma (is_marker_for)	MUC16 MUC3A MUC4	1.67e-04	64	49	3	DOID:4947 (is_marker_for)
Disease	anxiety disorder, stress-related disorder	GIGYF2 SDK1	1.76e-04	12	49	2	EFO_0006788, EFO_0010098
Disease	cholangiocarcinoma (biomarker_via_orthology)	TNC MUC4	2.08e-04	13	49	2	DOID:4947 (biomarker_via_orthology)
Disease	Sjogren's syndrome (is_marker_for)	MUC19 MUC16	7.28e-04	24	49	2	DOID:12894 (is_marker_for)
Disease	necrotizing enterocolitis	TCF20 KIAA1328	9.23e-04	27	49	2	EFO_0003928
Disease	internet addiction disorder	FLNB ZNF804A	1.38e-03	33	49	2	EFO_0803368
Disease	Global developmental delay	CDK8 CACNA1B TCF20	1.42e-03	133	49	3	C0557874
Disease	bullous pemphigoid	FLNB TNC	1.46e-03	34	49	2	EFO_0007187

Protein segments in the cluster

Peptide	Gene	Start	Entry
KGGPEMASLSSSVVP	ARMS2	16	P0C7Q2
IKTSVTGTSMPTGAV	EP400	2616	Q96L91
VGTTVTMTGNGTRPP	BAG6	381	P46379
SGMGIAVSTPSTQKP	GRAMD4	531	Q6IC98
PPKTGAVVIDMGTGT	ACTL9	46	Q8TC94
PSIGPVSRGMKESIS	DNHD1	2751	Q96M86
STVSPGGYMVPKGTT	AHDC1	1061	Q5TGY3
TSGTVTVGPMHTLPS	CACNA1B	1031	Q00975
PTTSETGTPRVEGMV	ADAMTS12	1226	P58397
VGTSAGVVLTMPTSP	ARHGEF17	1936	Q96PE2
PAGTTIVKTMAVTPG	HCFC1	571	P51610
GGTKPSYTMVSSVIP	MUC16	666	Q8WXI7
ESTDMAITPKTGPSG	MUC16	9361	Q8WXI7
PGMVKTTDTSTEPGT	MUC16	10056	Q8WXI7
MVTSPGVDTRSGVPT	MUC16	11606	Q8WXI7
AIPVSTGMASSIVPG	MUC4	856	Q99102
ETPGMTTPSLKTDGG	MUC4	4261	Q99102
PPTGTDTMVKAGVST	NUP98	166	P52948
MPVIPKGSSVGTGTN	PRKD1	541	Q15139
LETSKGTSGPPVTMA	SPN	176	P16150
STMSPGTVGQSLKSP	KIAA1109	4346	Q2LD37
TGEVHMPSGKTATPE	FLNB	1761	O75369
PIRGPESGGTMVTIT	PLXNA2	961	O75051
VTTPEKSPGVAMTTG	MUC19	2456	Q7Z5P9
MEPPSTTVATTGTGQ	MUC3A	1336	Q02505
SMCFTKPGAEVPTGT	PINLYP	176	A6NC86
PGVMGTSVATSASKI	NUP214	1046	P35658
SMLPGSGSVPKKSTE	TUBGCP5	341	Q96RT8
GVRKDASTSPMPTGS	KIAA1328	476	Q86T90
GITAGSTDEPPMLTK	BCL7C	151	Q8WUZ0
ETPVVGAPGMGSVST	GIGYF2	466	Q6Y7W6
VGSKSEMTASPLVGP	MARK1	466	Q9P0L2
ASPKAGVGMAPEVST	MAP7D3	321	Q8IWC1
LQTGSMVKPVSPAGT	FAM110B	6	Q8TC76
VVPPTTTSGGLIMTS	CDK8	406	P49336
VGPEMTGVTVSGLTP	SDK1	721	Q7Z5N4
TLPPSGGKSEESGMV	SALL1	616	Q9NSC2
KMISVSGGGLPPVST	HNF1B	401	P35680
SLGPMGSVVKSEPSS	SOX3	366	P41225
MANSTAVVKIPGTPG	TAF12	31	Q16514
PATIMTSSVPTTVGG	SRF	391	P11831
GVSPMPGTQKDTGRT	NCAPH2	206	Q6IBW4
PSSGGSGIPEVKTML	CLCNKB	116	P51801
SGTMGTKGHTEVIVP	UBA6	591	A0AVT1
SATVSSSVPMPAGGK	SPATA20	36	Q8TB22
PITGGTPSMVTVDGT	TNC	1746	P24821
AETVTAGKEPPGAMT	TCF20	1451	Q9UGU0
AGKEPPGAMTSTTSQ	TCF20	1456	Q9UGU0
EVSTMVESPAAPGKG	MYO18B	421	Q8IUG5
TSGGMKPSSVSVPQC	TXNDC11	476	Q6PKC3
DSGISVSKTPIMKPG	ZHX2	176	Q9Y6X8
VMVQPSKTATGPSTG	ZNF687	471	Q8N1G0
SSPSAVVVEMGSKPA	SH3RF2	561	Q8TEC5
PGSGPMFKSTTVTVR	ZNF804A	131	Q7Z570
GSMETTALPGSTTKP	MUC12	616	Q9UKN1