Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionRNA polymerase II cis-regulatory region sequence-specific DNA binding

ZNF219 GLIS3 POU3F2 POU3F3 POU3F4 ZNF784 SOX7 KLF16 ZSCAN10 SATB1 HEY1 ZIC5 GLI3 SKOR2 ZNF575 SP6 NLRC5 MAF

9.10e-05124410618GO:0000978
GeneOntologyMolecularFunctiontransmembrane receptor protein tyrosine kinase adaptor activity

IRS1 SH2B2 IRS2

1.12e-04181063GO:0005068
GeneOntologyMolecularFunctioncis-regulatory region sequence-specific DNA binding

ZNF219 GLIS3 POU3F2 POU3F3 POU3F4 ZNF784 SOX7 KLF16 ZSCAN10 SATB1 HEY1 ZIC5 GLI3 SKOR2 ZNF575 SP6 NLRC5 MAF

1.19e-04127110618GO:0000987
GeneOntologyMolecularFunctionDNA-binding transcription factor activity, RNA polymerase II-specific

ZNF219 GLIS3 POU3F2 POU3F3 POU3F4 ZNF784 SOX7 KLF16 ZSCAN10 SATB1 HEY1 ZIC5 GLI3 SKOR2 ZNF575 NFX1 SP6 ZNF579 MAF

1.47e-04141210619GO:0000981
GeneOntologyMolecularFunctionRNA polymerase II transcription regulatory region sequence-specific DNA binding

ZNF219 GLIS3 POU3F2 POU3F3 POU3F4 ZNF784 SOX7 KLF16 ZSCAN10 SATB1 HEY1 ZIC5 GLI3 SKOR2 ZNF575 NFX1 SP6 NLRC5 MAF

2.24e-04145910619GO:0000977
GeneOntologyMolecularFunctionbicarbonate transmembrane transporter activity

BEST1 SLC39A10 SLC4A9

6.45e-04321063GO:0015106
GeneOntologyMolecularFunctionNMDA glutamate receptor activity

GRIN3A GRIN3B

7.66e-0481062GO:0004972
GeneOntologyMolecularFunctionphosphatidylinositol 3-kinase activator activity

IRS1 IRS2

9.81e-0491062GO:0141038
DomainTF_POU_3

POU3F2 POU3F3 POU3F4

7.08e-0741063IPR016362
Domain-

POU3F2 POU3F3 POU3F4 SATB1

1.56e-052710641.10.260.40
DomainLambda_DNA-bd_dom

POU3F2 POU3F3 POU3F4 SATB1

2.09e-05291064IPR010982
DomainSec16

SEC16B SEC16A

3.19e-0521062IPR024880
DomainSec16

SEC16B SEC16A

3.19e-0521062PF12932
DomainSec16_CCD

SEC16B SEC16A

3.19e-0521062IPR024340
DomainPOU

POU3F2 POU3F3 POU3F4

9.43e-05161063SM00352
DomainPOU_2

POU3F2 POU3F3 POU3F4

9.43e-05161063PS00465
DomainPOU_dom

POU3F2 POU3F3 POU3F4

9.43e-05161063IPR000327
DomainPOU_3

POU3F2 POU3F3 POU3F4

9.43e-05161063PS51179
DomainPou

POU3F2 POU3F3 POU3F4

9.43e-05161063PF00157
DomainPOU_1

POU3F2 POU3F3 POU3F4

9.43e-05161063PS00035
DomainSec16_C

SEC16B SEC16A

9.54e-0531062PF12931
DomainACE1_Sec16_Sec31

SEC16B SEC16A

9.54e-0531062IPR024298
DomainPOU

POU3F2 POU3F3 POU3F4

1.14e-04171063IPR013847
DomainPH

KALRN PHLDA1 IRS1 PLEKHG2 SH2B2 IRS2 APBB1IP SPATA13

1.86e-042781068SM00233
DomainPH_DOMAIN

KALRN PHLDA1 IRS1 PLEKHG2 SH2B2 IRS2 APBB1IP SPATA13

1.91e-042791068PS50003
DomainPH_domain

KALRN PHLDA1 IRS1 PLEKHG2 SH2B2 IRS2 APBB1IP SPATA13

1.96e-042801068IPR001849
DomainPH

KALRN IRS1 PLEKHG2 SH2B2 IRS2 APBB1IP SPATA13

3.31e-042291067PF00169
DomainAPC_su10/DOC_dom

MYCBP2 CUL9

6.58e-0471062IPR004939
DomainDOC

MYCBP2 CUL9

6.58e-0471062PS51284
DomainAPC10

MYCBP2 CUL9

6.58e-0471062SM01337
DomainANAPC10

MYCBP2 CUL9

6.58e-0471062PF03256
DomainPH_dom-like

KALRN PHLDA1 IRS1 PLEKHG2 SH2B2 MTMR11 IRS2 APBB1IP SPATA13

7.17e-044261069IPR011993
DomainPTBI

IRS1 IRS2

1.70e-03111062SM00310
Domain-

KALRN PHLDA1 IRS1 PLEKHG2 SH2B2 IRS2 APBB1IP SPATA13

1.74e-0339110682.30.29.30
DomainSAM_2

INPPL1 PPFIA1 SAMD12

1.86e-03431063PF07647
DomainIRS_PTB

IRS1 IRS2

2.03e-03121062PS51064
DomainIRS_PTB

IRS1 IRS2

2.78e-03141062IPR002404
DomainIBR

RNF31 CUL9

2.78e-03141062SM00647
DomainIBR

RNF31 CUL9

2.78e-03141062PF01485
DomainIRS

IRS1 IRS2

2.78e-03141062PF02174
DomainIBR_dom

RNF31 CUL9

3.19e-03151062IPR002867
DomainSAM/pointed

INPPL1 PPFIA1 SAMD12 KIDINS220

4.45e-031171064IPR013761
DomainZINC_FINGER_C2H2_2

ZNF219 GLIS3 ZNF784 KLF16 ZSCAN10 ZIC5 GLI3 ZNF575 HELZ2 SP6 ZNF579

4.52e-0377510611PS50157
DomainIontro_rcpt

GRIN3A GRIN3B

4.60e-03181062IPR001320
DomainLig_chan-Glu_bd

GRIN3A GRIN3B

4.60e-03181062PF10613
DomainIono_rcpt_met

GRIN3A GRIN3B

4.60e-03181062IPR001508
DomainGlu/Gly-bd

GRIN3A GRIN3B

4.60e-03181062IPR019594
DomainLig_chan-Glu_bd

GRIN3A GRIN3B

4.60e-03181062SM00918
DomainLig_chan

GRIN3A GRIN3B

4.60e-03181062PF00060
DomainPBPe

GRIN3A GRIN3B

4.60e-03181062SM00079
DomainZINC_FINGER_C2H2_1

ZNF219 GLIS3 ZNF784 KLF16 ZSCAN10 ZIC5 GLI3 ZNF575 HELZ2 SP6 ZNF579

4.61e-0377710611PS00028
Domain-

ZNF219 GLIS3 ZNF784 KLF16 ZSCAN10 ZIC5 GLI3 ZNF575 SP6 ZNF579

5.23e-03679106103.30.160.60
DomainZnf_C2H2-like

ZNF219 GLIS3 ZNF784 KLF16 ZSCAN10 ZIC5 GLI3 ZNF575 HELZ2 SP6 ZNF579

5.51e-0379610611IPR015880
DomainDH_1

KALRN PLEKHG2 SPATA13

5.51e-03631063PS00741
DomainZnf_C2H2/integrase_DNA-bd

ZNF219 GLIS3 ZNF784 KLF16 ZSCAN10 ZIC5 GLI3 ZNF575 SP6 ZNF579

6.08e-0369410610IPR013087
DomainZnF_C2H2

ZNF219 GLIS3 ZNF784 KLF16 ZSCAN10 ZIC5 GLI3 ZNF575 HELZ2 SP6 ZNF579

6.15e-0380810611SM00355
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

KALRN MYCBP2 SZT2 BICRA INPPL1 CUL9 DGKQ IRS1 SH2B2 SEC16A NFX1 HELZ2 NLRC5 AP1G2 IRS2 ZNF579 ABCC10 SPATA13

1.04e-0811051091835748872
Pubmed

Class III POU genes: generation of homopolymeric amino acid repeats under GC pressure in mammals.

POU3F2 POU3F3 POU3F4

2.99e-08310938703082
Pubmed

Structure and evolution of four POU domain genes expressed in mouse brain.

POU3F2 POU3F3 POU3F4

1.20e-07410931565620
Pubmed

The class III POU factor Brn-4 interacts with other class III POU factors and the heterogeneous nuclear ribonucleoprotein U.

POU3F2 POU3F3 POU3F4

2.98e-07510939105675
Pubmed

Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.

ZNF219 RNF31 PHLDA1 BICRA PPFIA1 WRNIP1 OBSL1 CUL9 INO80D ARID1B GLI3 SEC16A LRP2 TTC39A IRS2 ZNF579

4.13e-0711161091631753913
Pubmed

Chromosomal organization of mammalian POU domain factors.

POU3F2 POU3F3 POU3F4

2.48e-06910938276396
Pubmed

Identification of Pax2-regulated genes by expression profiling of the mid-hindbrain organizer region.

POU3F2 POU3F3 POU3F4

2.48e-069109315872005
Pubmed

CD spectra show the relational style between Zic-, Gli-, Glis-zinc finger protein and DNA.

GLIS3 ZIC5 GLI3

3.54e-0610109318298960
Pubmed

Murine chromosomal location of four class III POU transcription factors.

POU3F2 POU3F3 POU3F4

6.45e-061210938276397
Pubmed

Development and survival of the endocrine hypothalamus and posterior pituitary gland requires the neuronal POU domain factor Brn-2.

POU3F2 POU3F3 POU3F4

8.37e-061310938543156
Pubmed

Impact of cytosine methylation on DNA binding specificities of human transcription factors.

POU3F2 POU3F4 ZNF784 SOX7 KLF16 HEY1 ZIC5 GLI3 SKOR2 MAF

8.62e-065441091028473536
Pubmed

Clearance of HCV improves insulin resistance, beta-cell function, and hepatic expression of insulin receptor substrate 1 and 2.

IRS1 IRS2

9.73e-062109217222321
Pubmed

Insulin receptor substrate-1/2 mediates IL-4-induced migration of human airway epithelial cells.

IRS1 IRS2

9.73e-062109219447894
Pubmed

Divergent roles for IRS-1 and IRS-2 in breast cancer metastasis.

IRS1 IRS2

9.73e-062109217361103
Pubmed

Disruption of IRS-2 causes type 2 diabetes in mice.

IRS1 IRS2

9.73e-06210929495343
Pubmed

Phosphorylation of insulin receptor substrates (IRS-1 and IRS-2) is attenuated following cecal ligation and puncture in mice.

IRS1 IRS2

9.73e-062109237550630
Pubmed

Insulin receptor substrate 1, but not IRS2, plays a dominant role in regulating pancreatic alpha cell function in mice.

IRS1 IRS2

9.73e-062109233839150
Pubmed

Roles of Insulin Receptor Substrates (IRS) in renal function and renal hemodynamics.

IRS1 IRS2

9.73e-062109233270683
Pubmed

The transcriptional coregulator CITED2 suppresses expression of IRS-2 and impairs insulin signaling in endothelial cells.

CITED2 IRS2

9.73e-062109234151583
Pubmed

BRN4 Is a Novel Driver of Neuroendocrine Differentiation in Castration-Resistant Prostate Cancer and Is Selectively Released in Extracellular Vesicles with BRN2.

POU3F2 POU3F4

9.73e-062109231371344
Pubmed

Nucleotide sequence, genomic organization, and chromosomal localization of genes encoding the human NMDA receptor subunits NR3A and NR3B.

GRIN3A GRIN3B

9.73e-062109211735224
Pubmed

Roles of insulin receptor substrates in insulin-induced stimulation of renal proximal bicarbonate absorption.

IRS1 IRS2

9.73e-062109215975995
Pubmed

Systematic modeling for the insulin signaling network mediated by IRS(1) and IRS(2).

IRS1 IRS2

9.73e-062109224703981
Pubmed

Differential hepatic distribution of insulin receptor substrates causes selective insulin resistance in diabetes and obesity.

IRS1 IRS2

9.73e-062109227708333
Pubmed

Impairment of bone healing by insulin receptor substrate-1 deficiency.

IRS1 IRS2

9.73e-062109214736890
Pubmed

Evidence for lifespan extension and delayed age-related biomarkers in insulin receptor substrate 1 null mice.

IRS1 IRS2

9.73e-062109217928362
Pubmed

Impaired insulin signaling in endothelial cells reduces insulin-induced glucose uptake by skeletal muscle.

IRS1 IRS2

9.73e-062109221356519
Pubmed

The study on the relationship between IRS-1 Gly972Arg and IRS-2 Gly1057Asp polymorphisms and type 2 diabetes in the Kurdish ethnic group in West Iran.

IRS1 IRS2

9.73e-062109222994406
Pubmed

Caspase-mediated Cleavage of Insulin Receptor Substrate.

IRS1 IRS2

9.73e-062109215069074
Pubmed

The Irs1 branch of the insulin signaling cascade plays a dominant role in hepatic nutrient homeostasis.

IRS1 IRS2

9.73e-062109219596788
Pubmed

Insulin receptor substrate (IRS)-2, not IRS-1, protects human neuroblastoma cells against apoptosis.

IRS1 IRS2

9.73e-062109219259821
Pubmed

Lack of insulin receptor substrate-2 causes progressive neointima formation in response to vessel injury.

IRS1 IRS2

9.73e-062109212810606
Pubmed

Overexpression of insulin receptor substrate-1, but not insulin receptor substrate-2, protects a T cell hybridoma from activation-induced cell death.

IRS1 IRS2

9.73e-062109212055235
Pubmed

Role of allelic variants Gly972Arg of IRS-1 and Gly1057Asp of IRS-2 in moderate-to-severe insulin resistance of women with polycystic ovary syndrome.

IRS1 IRS2

9.73e-062109211522686
Pubmed

Association of IRS1 (Gly972Arg) and IRS2 (Gly1057Asp) genes polymorphisms with OSA and NAFLD in Asian Indians.

IRS1 IRS2

9.73e-062109234449768
Pubmed

Irs1 serine 307 promotes insulin sensitivity in mice.

IRS1 IRS2

9.73e-062109220074531
Pubmed

Role of IRS-2 in insulin and cytokine signalling.

IRS1 IRS2

9.73e-06210927675087
Pubmed

Selective insulin resistance with differential expressions of IRS-1 and IRS-2 in human NAFLD livers.

IRS1 IRS2

9.73e-062109229717275
Pubmed

Increased expression of the sterol regulatory element-binding protein-1 gene in insulin receptor substrate-2(-/-) mouse liver.

IRS1 IRS2

9.73e-062109211546755
Pubmed

Increased insulin resistance in obese children who have both 972 IRS-1 and 1057 IRS-2 polymorphisms.

IRS1 IRS2

9.73e-062109212475767
Pubmed

Variations in insulin secretion in carriers of gene variants in IRS-1 and -2.

IRS1 IRS2

9.73e-062109211872698
Pubmed

Essential role of insulin receptor substrate 1 (IRS-1) and IRS-2 in adipocyte differentiation.

IRS1 IRS2

9.73e-062109211259600
Pubmed

Relationship of insulin receptor substrate-1 and -2 genotypes to phenotypic features of polycystic ovary syndrome.

IRS1 IRS2

9.73e-062109212213887
Pubmed

Association of IRS-1 and IRS-2 genes polymorphisms with polycystic ovary syndrome: a meta-analysis.

IRS1 IRS2

9.73e-062109222523112
Pubmed

Selective Insulin Resistance in the Kidney.

IRS1 IRS2

9.73e-062109227247938
Pubmed

Decreased lactation capacity and altered milk composition in insulin receptor substrate null mice is associated with decreased maternal body mass and reduced insulin-dependent phosphorylation of mammary Akt.

IRS1 IRS2

9.73e-062109217641282
Pubmed

Night-Shift Work Duration and Risk of Colorectal Cancer According to IRS1 and IRS2 Expression.

IRS1 IRS2

9.73e-062109231666286
Pubmed

Differential involvement of insulin receptor substrate (IRS)-1 and IRS-2 in brain insulin signaling is associated with the effects on amyloid pathology in a mouse model of Alzheimer's disease.

IRS1 IRS2

9.73e-062109234537327
Pubmed

Association of Gly972Arg variant of insulin receptor subtrate-1 and Gly1057Asp variant of insulin receptor subtrate-2 with polycystic ovary syndrome in the Chinese population.

IRS1 IRS2

9.73e-062109225310961
Pubmed

Insulin Receptor Substrate Adaptor Proteins Mediate Prognostic Gene Expression Profiles in Breast Cancer.

IRS1 IRS2

9.73e-062109226991655
Pubmed

Overexpression of IRS2 in isolated pancreatic islets causes proliferation and protects human beta-cells from hyperglycemia-induced apoptosis.

IRS1 IRS2

9.73e-062109215572028
Pubmed

Association of IRS-1 and IRS-2 polymorphisms with predisposition to type-2 diabetes (T2D): a meta-analysis and trial sequential analysis.

IRS1 IRS2

9.73e-062109237173295
Pubmed

Insulin receptor substrates are essential for the bioenergetic and hypertrophic response of the heart to exercise training.

IRS1 IRS2

9.73e-062109225002528
Pubmed

Targeting type 2 diabetes: lessons from a knockout model of insulin receptor substrate 2.

IRS1 IRS2

9.73e-062109224977713
Pubmed

Down-regulation of Insulin Receptor Substrate 1 during Hyperglycemia Induces Vascular Smooth Muscle Cell Dedifferentiation.

IRS1 IRS2

9.73e-062109228003360
Pubmed

Disruption of insulin receptor substrate 2 causes type 2 diabetes because of liver insulin resistance and lack of compensatory beta-cell hyperplasia.

IRS1 IRS2

9.73e-062109211078455
Pubmed

Genetic variation in N-methyl-D-aspartate receptor subunit NR3A but not NR3B influences susceptibility to Alzheimer's disease.

GRIN3A GRIN3B

9.73e-062109220016182
Pubmed

PDGF-induced vascular smooth muscle cell proliferation is associated with dysregulation of insulin receptor substrates.

IRS1 IRS2

9.73e-062109221325637
Pubmed

Oncogenic transformation by the signaling adaptor proteins insulin receptor substrate (IRS)-1 and IRS-2.

IRS1 IRS2

9.73e-062109217374994
Pubmed

Irs1 and Irs2 signaling is essential for hepatic glucose homeostasis and systemic growth.

IRS1 IRS2

9.73e-062109216374520
Pubmed

Study of association of IRS-1 and IRS-2 genes polymorphisms with clinical and metabolic features in women with polycystic ovary syndrome. Is there an impact?

IRS1 IRS2

9.73e-062109220210696
Pubmed

Developmental and hormonal signals dramatically alter the localization and abundance of insulin receptor substrate proteins in the mammary gland.

IRS1 IRS2

9.73e-062109212746333
Pubmed

Prevalence of the insulin receptor substrate-1(IRS-1) Gly972Arg and the insulin receptor substrate-2(IRS-2) Gly1057Asp polymorphisms in PCOS patients and non-diabetic healthy women.

IRS1 IRS2

9.73e-062109222205343
Pubmed

Insulin receptor substrates 1 and 2 but not Shc can activate the insulin receptor independent of insulin and induce proliferation in CHO-IR cells.

IRS1 IRS2

9.73e-062109217222824
Pubmed

Insulin Receptor Substrate-1 (IRS-1) and IRS-2 expression levels are associated with prognosis in non-small cell lung cancer (NSCLC).

IRS1 IRS2

9.73e-062109231393907
Pubmed

Myocardial loss of IRS1 and IRS2 causes heart failure and is controlled by p38α MAPK during insulin resistance.

IRS1 IRS2

9.73e-062109224159000
Pubmed

Inhibition of TNF-α improves the bladder dysfunction that is associated with type 2 diabetes.

IRS1 IRS2

9.73e-062109222688336
Pubmed

Dysregulation of insulin receptor substrate 2 in beta cells and brain causes obesity and diabetes.

IRS1 IRS2

9.73e-062109215467829
Pubmed

Polymorphism analysis of the Gly972Arg IRS-1 and Gly1057Asp IRS-2 genes in obese pregnant women.

IRS1 IRS2

9.73e-062109232540195
Pubmed

The double life of Irs.

IRS1 IRS2

9.73e-062109218590687
Pubmed

Dynamic functional relay between insulin receptor substrate 1 and 2 in hepatic insulin signaling during fasting and feeding.

IRS1 IRS2

9.73e-062109218590692
Pubmed

Mammary tumorigenesis and metastasis caused by overexpression of insulin receptor substrate 1 (IRS-1) or IRS-2.

IRS1 IRS2

9.73e-062109217030631
Pubmed

Insulin receptor substrate 2 is essential for maturation and survival of photoreceptor cells.

IRS1 IRS2

9.73e-062109215689562
Pubmed

TMEPAI regulates EMT in lung cancer cells by modulating the ROS and IRS-1 signaling pathways.

IRS1 PMEPA1

9.73e-062109223615405
Pubmed

Proneural bHLH and Brn proteins coregulate a neurogenic program through cooperative binding to a conserved DNA motif.

POU3F2 POU3F3 POU3F4

1.06e-0514109317141158
Pubmed

A genome-wide screen to identify transcription factors expressed in pelvic Ganglia of the lower urinary tract.

ZNF219 RNF31 POU3F3 POU3F4 CITED2 SOX7 SATB1 HEY1 GLI3 NFX1 SP6

1.47e-057091091122988430
Pubmed

The winged helix gene, Mf3, is required for normal development of the diencephalon and midbrain, postnatal growth and the milk-ejection reflex.

POU3F2 POU3F3 POU3F4

1.63e-051610939118797
Pubmed

A census of human transcription factors: function, expression and evolution.

POU3F2 POU3F3 POU3F4 SOX7 KLF16 SATB1 HEY1 GLI3 SKOR2 NFX1 SP6 MAF

2.88e-059081091219274049
Pubmed

Cloning and characterization of PHIP, a novel insulin receptor substrate-1 pleckstrin homology domain interacting protein.

IRS1 IRS2

2.91e-053109211018022
Pubmed

Inhibition of PTP1B restores IRS1-mediated hepatic insulin signaling in IRS2-deficient mice.

IRS1 IRS2

2.91e-053109220028942
Pubmed

Associations of insulin receptor and insulin receptor substrates genetic polymorphisms with polycystic ovary syndrome: A systematic review and meta-analysis.

IRS1 IRS2

2.91e-053109227098445
Pubmed

Tamoxifen reduces fat mass by boosting reactive oxygen species.

IRS1 IRS2

2.91e-053109225569103
Pubmed

Targeted gene mutations define the roles of insulin and IGF-I receptors in mouse embryonic development.

IRS1 IRS2

2.91e-053109210417963
Pubmed

SH2B1 enhances insulin sensitivity by both stimulating the insulin receptor and inhibiting tyrosine dephosphorylation of insulin receptor substrate proteins.

IRS1 IRS2

2.91e-053109219542202
Pubmed

The proto-oncogene product c-Crk associates with insulin receptor substrate-1 and 4PS. Modulation by insulin growth factor-I (IGF) and enhanced IGF-I signaling.

IRS1 IRS2

2.91e-05310928621590
Pubmed

Glucose effects on beta-cell growth and survival require activation of insulin receptors and insulin receptor substrate 2.

IRS1 IRS2

2.91e-053109219273608
Pubmed

Insulin signaling and glucose homeostasis in mice lacking protein tyrosine phosphatase alpha.

IRS1 IRS2

2.91e-053109214733908
Pubmed

The type I interferon receptor mediates tyrosine phosphorylation of insulin receptor substrate 2.

IRS1 IRS2

2.91e-05310928550573
Pubmed

Study on insulin resistance and genetic polymorphisms in essential hypertension patients of two different kinds of TCM constitution.

IRS1 IRS2

2.91e-053109217898946
Pubmed

Insulin receptor isoforms A and B as well as insulin receptor substrates-1 and -2 are differentially expressed in prostate cancer.

IRS1 IRS2

2.91e-053109223251408
Pubmed

Polymorphisms of the insulin receptor and the insulin receptor substrates genes in polycystic ovary syndrome: a Mendelian randomization meta-analysis.

IRS1 IRS2

2.91e-053109219926323
Pubmed

Cellular growth inhibition by TGF-beta1 involves IRS proteins.

IRS1 IRS2

2.91e-053109215135063
Pubmed

The double-stranded RNA-dependent protein kinase differentially regulates insulin receptor substrates 1 and 2 in HepG2 cells.

IRS1 IRS2

2.91e-053109220685959
Pubmed

The cross-talk between angiotensin and insulin differentially affects phosphatidylinositol 3-kinase- and mitogen-activated protein kinase-mediated signaling in rat heart: implications for insulin resistance.

IRS1 IRS2

2.91e-053109212960006
Pubmed

Glucokinase and IRS-2 are required for compensatory beta cell hyperplasia in response to high-fat diet-induced insulin resistance.

IRS1 IRS2

2.91e-053109217200721
Pubmed

Characterization of human Sec16B: indications of specialized, non-redundant functions.

SEC16B SEC16A

2.91e-053109222355596
Pubmed

Insulin signaling and reduced glucocorticoid receptor activity attenuate postprandial gene expression in liver.

IRS1 IRS2

2.91e-053109230532187
Pubmed

RNA-binding protein, human antigen R regulates hypoxia-induced autophagy by targeting ATG7/ATG16L1 expressions and autophagosome formation.

ATG16L1 ELAVL1

2.91e-053109230317574
Pubmed

Characterization of Drosophila insulin receptor substrate.

IRS1 IRS2

2.91e-053109210801879
Pubmed

Selective alterations in insulin receptor substrates-1, -2 and -4 in theca but not granulosa cells from polycystic ovaries.

IRS1 IRS2

2.91e-053109215155816
InteractionPOU3F1 interactions

POU3F2 POU3F3 POU3F4 CCDC85A

2.35e-06191034int:POU3F1
InteractionPOU3F4 interactions

POU3F2 POU3F3 POU3F4

2.56e-0661033int:POU3F4
InteractionTOP3B interactions

KALRN MYCBP2 SZT2 BICRA INPPL1 CUL9 DGKQ IRS1 SH2B2 SEC16A NFX1 HELZ2 AHSG NLRC5 ELAVL1 AP1G2 IRS2 ZNF579 PRRC2A ABCC10 SPATA13

1.43e-05147010321int:TOP3B
GeneFamilyPOU class homeoboxes and pseudogenes

POU3F2 POU3F3 POU3F4

1.39e-0423803523
GeneFamilyPleckstrin homology domain containing|Rho guanine nucleotide exchange factors|C2 domain containing

IRS1 PLEKHG2 SH2B2 IRS2 APBB1IP SPATA13

3.03e-04206806682
GeneFamilyGlutamate ionotropic receptor NMDA type subunits

GRIN3A GRIN3B

4.00e-0478021201
GeneFamilyZinc fingers C2H2-type|ZF class homeoboxes and pseudogenes

ZNF219 GLIS3 ZNF784 KLF16 ZSCAN10 ZIC5 GLI3 ZNF575 SP6 ZNF579

1.23e-03718801028
GeneFamilyPleckstrin homology domain containing|Rho guanine nucleotide exchange factors|C2 domain containing

KALRN PLEKHG2 SPATA13

3.12e-0366803722
CoexpressionIKEDA_MIR30_TARGETS_UP

PPFIA1 IRS1 B4GALT5 MAN1A2 IRS2 MAF

7.85e-061161066M2379
CoexpressionIKEDA_MIR30_TARGETS_UP

PPFIA1 IRS1 B4GALT5 MAN1A2 IRS2 MAF

8.25e-061171066MM931
CoexpressionGSE30083_SP1_VS_SP2_THYMOCYTE_DN

POU3F2 B4GALT5 STPG3 NLRC5 AP1G2 GRIN3B MMP11

1.75e-052001067M5024
CoexpressionFAN_EMBRYONIC_CTX_EX_2_EXCITATORY_NEURON

PHLDA1 POU3F2 IGFBPL1

3.46e-05161063M39025
CoexpressionGSE37532_VISCERAL_ADIPOSE_TISSUE_VS_LN_DERIVED_TREG_CD4_TCELL_DN

CRTC3 BICRA INO80D ARID1B AHSG MAF

4.07e-051551066M8944
CoexpressionAtlasFacebaseRNAseq_e8.5_Non-Floor Plate Neural Epithelium_top-relative-expression-ranked_1000

PHLDA1 LAG3 GLIS3 PMEPA1 IGFBPL1 MTMR11 ZSCAN10 STC2 ZIC5 GLI3 ZNF575 LRP2 ASTN1 ZNF579 MMP11 SPATA13 MAF

3.82e-0697610217Facebase_RNAseq_e8.5_Non-Floor Plate Neural Epithelium_1000
CoexpressionAtlasFacebaseRNAseq_e10.5_Olfactory Pit_top-relative-expression-ranked_1000

ZNF219 PHLDA1 LAG3 GLIS3 IRS1 PMEPA1 IGFBPL1 MTMR11 ZSCAN10 STC2 HEY1 ZNF575 LRP2 ASTN1 ZNF579 MMP11

1.79e-0598410216Facebase_RNAseq_e10.5_Olfactory Pit_1000
CoexpressionAtlasFacebaseRNAseq_e8.5_Non-Floor Plate Neural Epithelium_top-relative-expression-ranked_500

PHLDA1 GLIS3 IGFBPL1 ZSCAN10 STC2 ZIC5 GLI3 LRP2 ZNF579 SPATA13 MAF

2.33e-0548910211Facebase_RNAseq_e8.5_Non-Floor Plate Neural Epithelium_500
CoexpressionAtlasFacebaseRNAseq_e8.5_Floor Plate_top-relative-expression-ranked_2500_k-means-cluster#5

ZNF219 BICRA GLIS3 OBSL1 IRS1 YIPF2 ZSCAN10 LRP2 MAF

2.92e-053281029Facebase_RNAseq_e8.5_Floor Plate_2500_K5
CoexpressionAtlasFacebaseRNAseq_e9.5_Maxillary Arch_top-relative-expression-ranked_1000

PHLDA1 LAG3 GLIS3 POU3F3 POU3F4 ZNF784 PMEPA1 CCDC85A CITED2 MTMR11 ZNF575 ASTN1 ZNF579 MMP11 APBB1IP

5.76e-0596710215Facebase_RNAseq_e9.5_Maxillary Arch_1000
CoexpressionAtlasFacebaseRNAseq_ratio_e9.5_MaxillaryArch_vs_Mandibular_top-relative-expression-ranked_500

GLIS3 POU3F3 POU3F4 PMEPA1 CCDC85A ZNF575 ASTN1 ZNF579 MMP11 MAF

1.21e-0448810210Facebase_RNAseq_ratio_e9.5_MaxillaryArch_vs_Mandibular_500
CoexpressionAtlasFacebaseRNAseq_ratio_e9.5_MaxillaryArch_vs_Mandibular_top-relative-expression-ranked_500_k-means-cluster#2

POU3F3 POU3F4 CCDC85A ASTN1 ZNF579

1.22e-041001025Facebase_RNAseq_ratio_e9.5_MaxillaryArch_vs_Mandibular_500_K2
CoexpressionAtlasFacebaseRNAseq_e8.5_Non-Floor Plate Neural Epithelium_top-relative-expression-ranked_1000_k-means-cluster#2

LAG3 IGFBPL1 ZIC5 GLI3 ASTN1 ZNF579 SPATA13

1.96e-042481027Facebase_RNAseq_e8.5_Non-Floor Plate Neural Epithelium_1000_K2
CoexpressionAtlasFacebaseRNAseq_ratio_e9.5_MaxillaryArch_vs_Mandibular_top-relative-expression-ranked_1000_k-means-cluster#2

LAG3 POU3F3 POU3F4 ZNF784 CCDC85A ASTN1 ZNF579

2.01e-042491027Facebase_RNAseq_ratio_e9.5_MaxillaryArch_vs_Mandibular_1000_K2
CoexpressionAtlasFacebaseRNAseq_ratio_e9.5_MaxillaryArch_vs_Mandibular_top-relative-expression-ranked_1000

LAG3 GLIS3 POU3F3 POU3F4 ZNF784 PMEPA1 CCDC85A MTMR11 ZNF575 ASTN1 ZNF579 MMP11 APBB1IP MAF

2.25e-0497210214Facebase_RNAseq_ratio_e9.5_MaxillaryArch_vs_Mandibular_1000
CoexpressionAtlasFacebaseRNAseq_e9.5_Olfactory Placode_top-relative-expression-ranked_1000

ZNF219 PHLDA1 LAG3 GLIS3 PMEPA1 IGFBPL1 ZSCAN10 HEY1 ZNF575 LRP2 ASTN1 ZNF579 MMP11 SPATA13

2.27e-0497310214Facebase_RNAseq_e9.5_Olfactory Placode_1000
CoexpressionAtlasalpha beta T cells, T.4Mem.LN, TCRb CD44high CD122lo CD4, Lymph Node, avg-3

LAG3 PLEKHG2 TESPA1 SATB1 SP6 NLRC5 SPATA13 MAF

2.76e-043481028GSM538362_500
ToppCellNon-neuronal-Non-dividing-Radial_Glia-early|World / Primary Cells by Cluster

ZNF219 PHLDA1 CITED2 STC2 HEY1 GLI3 ELAVL1

5.35e-071991077549391e7a4285da1c0e366654530bcf1cd33fbae
ToppCellNon-neuronal-Non-dividing-Radial_Glia-early-40|World / Primary Cells by Cluster

ZNF219 PHLDA1 CITED2 STC2 HEY1 GLI3 ELAVL1

5.35e-07199107723625d757173bdd35a51c7919ff4b588168d2553
ToppCelldroplet-Marrow-nan-21m-Lymphocytic-NK_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GALNS B4GALT5 CITED2 HEY1 AHSG RPL3L

3.63e-061711076355a27ea88410a84210f7e4298c7c4f90cf2f8a9
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

KALRN CDK15 PHLDA1 COL5A3 PLEKHG2 GLI3

6.85e-0619110767b0d42a877540dbb346a76a62403e0d5d3e07fa6
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

KALRN CDK15 PHLDA1 COL5A3 PLEKHG2 GLI3

6.85e-061911076cd854b9c426924fdc84bf7f411f6dea447143e79
ToppCell367C-Endothelial_cells-Endothelial-E-|367C / Donor, Lineage, Cell class and subclass (all cells)

CCDC85A SHROOM4 SOX7 STC2 HEY1 SP6

7.71e-06195107665fc50e3818e902028fc4226070fa57609c66b9c
ToppCell367C-Endothelial_cells-Endothelial-E|367C / Donor, Lineage, Cell class and subclass (all cells)

CCDC85A SHROOM4 SOX7 STC2 HEY1 SP6

7.71e-0619510763b79e6bb525b17192ecec9e1227a29c419968144
ToppCellLung_Parenchyma-Control-Endothelial-Endothelial-Capillary|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

CCDC85A SHROOM4 SOX7 STC2 HEY1 SP6

8.66e-0619910763fea92affacd4c1f588fa81807df35d6c69b7241
ToppCellLung_Parenchyma-Control-Endothelial-Endothelial-Capillary-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

CCDC85A SHROOM4 SOX7 STC2 HEY1 SP6

8.66e-061991076993999adf346b4fd557989bc53c17eb0ccb996c9
ToppCellParenchyma_Control_(B.)-Endothelial-TX-Capillary|Parenchyma_Control_(B.) / Sample group, Lineage and Cell type

CCDC85A SHROOM4 SOX7 STC2 HEY1 SP6

8.66e-06199107689f4db619fbed90f7fdf6ece7a671e514b5c6d76
ToppCellControl-Epithelial_alveolar-AT_2-AT1-AT2|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

LAG3 ZSCAN10 ZNF575 VWA3B TTC39A

9.39e-061171075c6fc72608d56a389bcd87b5dc98a11e39b79bcb2
ToppCelldroplet-Heart-nan-24m-Hematologic-red_blood_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SEC16B TAGAP LAG3 DGKQ

1.01e-0556107455337ff90621e1fea4d747ae2559c0fa61b38dce
ToppCellCerebellum-Endothelial-MURAL-M1(Rgs5Acta2)-M1_3|Cerebellum / BrainAtlas - Mouse McCarroll V32

CDK15 ZNF575 SP6 VWA3B MMP11

1.81e-0513410758a3acf32cabc37b49d6488d43cdaae7cec79d119
ToppCellCerebellum-Endothelial-MURAL-M1(Rgs5Acta2)-M1_3-MURAL_Mural.Acta2Rgs5.Rgs5_(Mural.Acta2Rgs5.Rgs5)|Cerebellum / BrainAtlas - Mouse McCarroll V32

CDK15 ZNF575 SP6 VWA3B MMP11

1.81e-0513410751fa13185a4dfb4563473184c0c4f449011d88631
ToppCellCerebellum-Endothelial-MURAL-M1(Rgs5Acta2)-M1_3-MURAL_Mural.Acta2Rgs5.Rgs5_(Mural.Acta2Rgs5.Rgs5)-|Cerebellum / BrainAtlas - Mouse McCarroll V32

CDK15 ZNF575 SP6 VWA3B MMP11

1.81e-0513410751ab99a22d0d7657f62f8ea7d96bb24e88de54fd4
ToppCellsaliva-Severe-critical_progression_d28-40-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c03-ITGA4|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)

LAG3 ASB14 TESPA1 NBAS OR52N5

3.53e-051541075ec920cae12ea1d14b6c973f6e903f895f80e3c50
ToppCell5'-GW_trimst-2-SmallIntestine-Epithelial-neuro-epithelial-EC_cells_(NPW+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

GLIS3 SAMD12 POU3F4 CCDC87 KLB

3.64e-051551075498e52e2364ff44d3c0c707ba22468217031f5bd
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c11-GNLY|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

LAG3 B4GALT5 SHROOM4 AUTS2 MAF

4.11e-05159107557df5c9b678a15eb5e025e1a80de2e6769cc13d5
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Immune-Myeloid-Granulocytic-Mast_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CDK15 TESPA1 B4GALT5 IRS2 MMP11

4.24e-051601075fe9970c160159b35f6599ed13c89cfb49264d554
ToppCell356C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_1|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

LAG3 RBM20 SCN2B SP6 NLRC5

4.50e-0516210754b9f80f701dcbb2508f497095cb8a7a2ca51cb5e
ToppCelldroplet-Liver-LIVER_HEP-30m-Myeloid-macrophage/monocyte|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BEST1 MYCBP2 GLIS3 PMEPA1 SCN2B

4.50e-05162107593bd29c52846c3156b8b0d2e39c552373efdfe93
ToppCellfacs-Marrow-T_cells-18m-Lymphocytic-late_pro_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KALRN USP42 SCN2B TTC39A FAM149A

4.91e-0516510750edd56e8d14eaeced9882dd9206ea93e8f402e8d
ToppCellfacs-Marrow-T_cells-18m-Lymphocytic-late_pro-B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KALRN USP42 SCN2B TTC39A FAM149A

4.91e-051651075fa3aadfff6fb1e7f142db333c60c2cba02b17e6c
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d02_child-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c01-LEF1|Mild-Moderate_progression_d02_child / Compartment, severity and other cell annotations on 10x 3' data (130k)

ATG16L1 TESPA1 SATB1 OR51M1

5.53e-0586107479c4326df78f0a5b3ef13b2fb4e5074934536e35
ToppCellSubstantia_nigra-Endothelial-MURAL-M1(Rgs5Acta2)-M1_3|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

CDK15 ASB14 SP6 FGG

5.53e-0586107480aa7f0a7e43f8278b1af25ced8c069325ed3270
ToppCell3'_v3-bone_marrow-Lymphocytic_Invariant-Inducer-like|bone_marrow / Manually curated celltypes from each tissue

PHLDA1 LAG3 COL5A3 SATB1 MAF

5.81e-0517110752977cffc146470733b5cfd8a1aa80d9346d4804d
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid-Granulocytic|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CDK15 TESPA1 B4GALT5 HEY1 IRS2

5.98e-0517210753a37569a5902f3c65ff8d3912421309a8c82ee9b
ToppCelldroplet-Liver-LIVER-30m-Myeloid-plasmacytoid_dendritic_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BEST1 TAGAP LAG3 SATB1 SCN2B

5.98e-05172107524ecfda5e43e28f190089770cd2eae5bf2ed292b
ToppCelldroplet-Liver-LIVER-30m-Myeloid-plasmacytoid_dendritic_cells|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BEST1 TAGAP LAG3 SATB1 SCN2B

5.98e-051721075db5a31cafce4346fe459d7f35210823fd7004439
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid-Granulocytic-Mast_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CDK15 TESPA1 B4GALT5 HEY1 IRS2

5.98e-051721075cc9d9dae290f11f8c348c78228af4e49469dc93b
ToppCellMild/Remission-B_naive-8|World / disease group and sub_cluster of B and Plasma cells(res = 0.5)

TAGAP PMEPA1 ARID1B OR52N5 IRS2

6.14e-051731075694d02c4d2dc2de4b344544f9124fec40fcf7d8f
ToppCellCOPD-Myeloid-pDC|World / Disease state, Lineage and Cell class

SAMD12 PMEPA1 ENAM AUTS2 TTC39A

6.31e-051741075be8227398300711ccda5ecc41ad34064bb246b19
ToppCellP15-Mesenchymal-mesenchymal_fibroblast-tracheal_fibroblast|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

LAG3 POU3F4 SH2B2 STC2 GLI3

6.49e-051751075085cceb1fc2c4ae2f27e85cea5702defecc2cf44
ToppCell3'_v3-lymph-node_spleen-Lymphocytic_Invariant-Inducer-like-MAIT|lymph-node_spleen / Manually curated celltypes from each tissue

PHLDA1 LAG3 CITED2 AUTS2 MAF

6.66e-05176107525c197d3b39deffa4801a1d12cdb54320cbae509
ToppCellsaliva-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_T|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

SEC16B ATG16L1 DDB2 TESPA1 MAF

6.66e-051761075dca70f309af24421f8dc708cbd88512814b8e79e
ToppCellsaliva-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

SEC16B ATG16L1 DDB2 TESPA1 MAF

6.84e-0517710759edfb50856f5e10672ab194ce0076d6a190e64de
ToppCellCOPD-Myeloid-pDC|COPD / Disease state, Lineage and Cell class

SAMD12 PMEPA1 ENAM AUTS2 TTC39A

6.84e-051771075415aa023195a7f961c09529f65cdcc7bb90eaf5d
ToppCellCOPD-Myeloid-pDC|Myeloid / Disease state, Lineage and Cell class

SAMD12 PMEPA1 ENAM AUTS2 TTC39A

7.22e-05179107529b058c5e33fda9f0d738c074bdb67ff16b9b6d5
ToppCell5'-Parenchyma_lung-Immune_Lymphocytic-Lymphocytic_T/NK-CD8-positive,_alpha-beta_T_cell-CD8_T_cells-CD8_T_cells_L.1.1.0.3|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PHLDA1 TAGAP LAG3 CITED2 APBB1IP

7.22e-0517910759af894dfbe44e9706f5d178769ceda3b4e2d89c0
ToppCellIPF-Myeloid-pDC|Myeloid / Disease state, Lineage and Cell class

SAMD12 PMEPA1 ENAM AUTS2 TTC39A

7.41e-0518010750f8567aa835d4e3a52f6631ae15216eca18a030c
ToppCellfacs-Brain_Non-Myeloid-Hippocampus-3m-Epithelial-neuronal_stem_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

INPPL1 IRS1 IGFBPL1 SATB1 ZNF579

7.61e-0518110754e81ec1580e9acb22c32c465eb46f83d1e9e424e
ToppCellfacs-Brain_Non-Myeloid-Hippocampus-3m-Epithelial|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

INPPL1 IRS1 IGFBPL1 SATB1 ZNF579

7.61e-051811075ad30c01290fb98adbd0caed301a584761212c977
ToppCellCOVID-19-Endothelial_cells-Capillary_endothelial_cells|COVID-19 / group, cell type (main and fine annotations)

KALRN SAMD12 CCDC85A SHROOM4 SOX7

7.61e-051811075c5f9c92af1384d9089c65afdf41c6feb8345a3ae
ToppCellfacs-Brain_Non-Myeloid-Hippocampus-3m-Epithelial-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

INPPL1 IRS1 IGFBPL1 SATB1 ZNF579

7.61e-0518110753a3268a4dff8ffcb79e09f46490e138c96f8d916
ToppCelldroplet-Lung-30m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell-pulmonary_artery_endothelial_cell_l25|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SAMD12 COL5A3 SHROOM4 SOX7 HEY1

8.01e-0518310756f8f997ffc9eaebca2683de125b6069d07c07d26
ToppCellfacs-Mammary_Gland-Mammary_Gland-21m|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PHLDA1 PMEPA1 KLF16 IRS2 PRRC2A

8.65e-051861075bd1185592aedebccd1007dbf2dd2f549fcdf9f42
ToppCell343B-Endothelial_cells-Endothelial-E-|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)

MTMR11 STC2 HEY1 AUTS2 SPATA13

8.65e-051861075dae6a98963c78bf7518ebab8dc02f173c3b0f7f7
ToppCelldroplet-Lung-21m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l1|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

PHLDA1 POU3F3 RBM20 GLI3 AHSG

8.65e-0518610757c1807fca590cdccf7f5734460bac228d33964ca
ToppCell343B-Endothelial_cells-Endothelial-E|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)

MTMR11 STC2 HEY1 AUTS2 SPATA13

8.65e-051861075080e56113b89138277a2bd2eabddfa6cd1a18b61
ToppCellIPF-Myeloid-cDC1|Myeloid / Disease state, Lineage and Cell class

LAG3 SAMD12 AUTS2 NLRC5 FAM149A

9.09e-05188107547bb6caf84f70a1cda7d09803afdfd5182772e66
ToppCellfacs-Mammary_Gland-Mammary_Gland-21m-Epithelial|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PHLDA1 PMEPA1 KLF16 IRS2 PRRC2A

9.32e-051891075965e0e388251e7318f8b463816dc96ccb4658677
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW09-Neuronal-Neuron|GW09 / Sample Type, Dataset, Time_group, and Cell type.

MYCBP2 PHLDA1 IGFBPL1 YIPF2 ABCC10

9.32e-0518910753717d1148e26ac78a26aea0ca1dbfbb9d3668877
ToppCellfacs-Mammary_Gland-Mammary_Gland-18m-Epithelial|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PHLDA1 HPS3 KLF16 HEY1 FGG

9.56e-05190107592456f6f7eced6e4c4371f495254a65d061c8d0b
ToppCellNeuron-Postmitotic-Excitatory_Neuron_-Deep_Layer-27|World / Primary Cells by Cluster

PHLDA1 SH2B2 IGFBPL1 CITED2 HEY1

1.00e-041921075cf989f26c0ebdc0cd12e1e41958f063e4fa3e468
ToppCellnucseq-Mesenchymal-Myocytic-Myocytic_2-SCMF|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

HECW1 IRS1 PMEPA1 GLI3 MMP11

1.00e-04192107567e845e513e76e820f55e2f0d15eb16f2944d05c
ToppCellPBMC-Mild-Lymphocyte-T/NK-CD8+_T-MAIT|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)

PHLDA1 LAG3 COL5A3 SATB1 MAF

1.00e-041921075892789bdba150ef9a8a0012de52545f2ff6a31f6
ToppCellCOVID-19_Mild-Lymphoid_T/NK-MAIT|COVID-19_Mild / Disease group, lineage and cell class

PHLDA1 LAG3 COL5A3 SATB1 MAF

1.00e-041921075d47bd132e57f5b4bddcf3dfa399cee149eca7e44
ToppCellPBMC-Mild-Lymphocyte-T/NK-CD8+_T-MAIT-|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

PHLDA1 LAG3 COL5A3 SATB1 MAF

1.00e-04192107524ea8fdcca2695aeb2e4b88161184124b7d332c1
ToppCellPBMC-Mild-Lymphocyte-T/NK-CD8+_T-MAIT-|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

PHLDA1 LAG3 COL5A3 SATB1 MAF

1.00e-04192107544f440ee3842fe14665c4cd4f2aa48e7a5bbd9a8
ToppCellPBMC-Mild-Lymphocyte-T/NK-CD8+_T-MAIT|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

PHLDA1 LAG3 COL5A3 SATB1 MAF

1.00e-0419210758d50ad8cfe3cb9f183188b08457756af0ce56ffe
ToppCellnucseq-Mesenchymal-Myocytic-Myocytic_2|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

HECW1 IRS1 PMEPA1 GLI3 MMP11

1.03e-0419310755de87fc94a6e58899ef4124cf4887ed3ff96163a
ToppCell10x_3'_v2v3-Neoplastic-Differentiated-like-MES-like-MES-like_hypoxia/MHC-E|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

GLIS3 OBSL1 POU3F2 B4GALT5 IRS2

1.05e-04194107508fad7591c20568de797cf8e206de2d0b1d78aab
ToppCelldroplet-Mammary_Gland-nan-3m-Epithelial-luminal_epithelial_cell_of_mammary_gland|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

INPPL1 RBM20 STC2 TTC39A FGG

1.05e-041941075715e02e5f3250b1bfdc26b7dfd656ba4e705ea84
ToppCellCOPD-Endothelial-VE_Capillary_B|COPD / Disease state, Lineage and Cell class

SHROOM4 SOX7 STC2 HEY1 SP6

1.05e-04194107518b7f901c12ca4f21f9a1eafd092aefe4d668b6d
ToppCellmild_COVID-19-MAIT|World / disease group, cell group and cell class (v2)

PHLDA1 LAG3 COL5A3 CITED2 MAF

1.08e-04195107574f0f709d9b3eed5d7e02a51884f02cc281782f1
ToppCellfacs-Brain_Myeloid-Hippocampus|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC39A10 PMEPA1 MAN1A2 APBB1IP MAF

1.08e-041951075a1478021a3ed0e779716393124ca2a7770c433b7
ToppCell3'_v3-GI_small-bowel-Lymphocytic_T_CD8|GI_small-bowel / Manually curated celltypes from each tissue

TAGAP LAG3 CITED2 AUTS2 APBB1IP

1.11e-0419610753f5bf202c5d8c15072255c133793c8ee6e8d932f
ToppCellhealthy_donor-Lymphocytic-T_cell-Gamma_Delta_T_cell|healthy_donor / Disease condition, Lineage, Cell class and subclass

LAG3 COL5A3 SATB1 AUTS2 MAF

1.11e-0419610756eabbac1625f715531bae562a28da27664572600
ToppCell3'_v3-GI_small-bowel-Lymphocytic_T_CD8-Trm_gut_CD8|GI_small-bowel / Manually curated celltypes from each tissue

TAGAP LAG3 CITED2 AUTS2 APBB1IP

1.11e-041961075528622874692d7d65c905738b078ab53acef5846
ToppCellNon-neuronal-Non-dividing-Radial_Glia-tRG|World / Primary Cells by Cluster

GLIS3 COL5A3 PMEPA1 RBM20 GLI3

1.13e-04197107561749ccafeb938c310cff1de5ff924a1c794325a
ToppCellParenchyma_Control_(B.)-Endothelial-TX-Endothelial-1|Parenchyma_Control_(B.) / Sample group, Lineage and Cell type

KALRN SHROOM4 SOX7 STC2 OR52N5

1.13e-041971075f969685dee212f33a6f09e54c0cd1fd24ffef546
ToppCellLung_Parenchyma-Control-Endothelial-Endothelial-Endothelial-1|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

KALRN SHROOM4 SOX7 STC2 OR52N5

1.13e-0419710751a137af40697137bb9d2b5caf2b1ffda55f04461
ToppCellNon-neuronal-Non-dividing-Radial_Glia-tRG-25|World / Primary Cells by Cluster

GLIS3 COL5A3 PMEPA1 RBM20 GLI3

1.13e-0419710759d4ffa3680f92c91d0a081f9a8ec5ebfec6bdcf6
ToppCell10x_3'_v3-lymph_node_(10x_3'_v3)-lymphocytic-T_lymphocytic-type_I_NK_T_cell|lymph_node_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

PHLDA1 COL5A3 CITED2 SATB1 MAF

1.13e-04197107551340570667914bffec741c72a8d09cc46abb8e8
ToppCellLung_Parenchyma-Control-Endothelial-Endothelial-Endothelial-1-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

KALRN SHROOM4 SOX7 STC2 OR52N5

1.13e-04197107596d63a8d00583e2aa0a38412e2ae27e23f399493
ToppCell5'-GW_trimst-2-LymphNode-Hematopoietic-T_cells-SELL+_CD8_T|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TAGAP TESPA1 SATB1 NLRC5 APBB1IP

1.16e-0419810750dac00a64fe08ec6669af3ddd4b82413b673233d
ToppCell10x5'-GI_small-bowel-Lymphocytic_T_CD4-Trm_Th1/Th17|GI_small-bowel / Manually curated celltypes from each tissue

PHLDA1 COL5A3 TESPA1 IRS2 MAF

1.16e-041981075f4fc0cac858fc6dcd779d7959ccec51f78ea8cc2
ToppCell3'_v3-GI_small-bowel-Lymphocytic_T_CD4|GI_small-bowel / Manually curated celltypes from each tissue

PHLDA1 TESPA1 SATB1 IRS2 MAF

1.16e-0419810756333e46cd1ccf5841ce15aea98a4b2f5e3ae4675
ToppCellBronchial-NucSeq-Immune_Lymphocytic-T-T_CD4-T_reg|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

TESPA1 SCN2B NLRC5 APBB1IP MAF

1.16e-0419810757608f67959e1cda7b10e57fd3af2f96216ebe7e9
ToppCell(6)_Endothelial-E|World / Lung cell shreds - cell class (v4) and cell subclass (v4)

CCDC85A SHROOM4 SOX7 STC2 HEY1

1.16e-041981075a5e1b321376caf262ea48904d31afd1b8e9d3be2
ToppCelldistal-1-mesenchymal-Mesothelial|1 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

UPK3B OBSL1 COL5A3 GLI3 ASTN1

1.19e-0419910758dd5b411d2f1626830b77a1616cc3fb67dc59338
ToppCellParenchyma_Control_(B.)-Endothelial-TX-Endothelial-2|Parenchyma_Control_(B.) / Sample group, Lineage and Cell type

CCDC85A SHROOM4 SOX7 HEY1 SP6

1.19e-041991075523e01f6a0abd9820697572e042a381aae8932dc
ToppCellLung_Parenchyma-Control-Endothelial-Endothelial-Endothelial-2-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

CCDC85A SHROOM4 SOX7 HEY1 SP6

1.19e-0419910750d0d5cb821db16514192ad536849a8a04e22e637
ToppCellSigmoid-T_cell-Tfh|Sigmoid / Region, Cell class and subclass

SATB1 OR51M1 HELZ2 NLRC5 TTC39A

1.19e-041991075fa9404a021a015d1d571c324780b6eef2da47c4c
ToppCellTracheal-NucSeq|Tracheal / Cell types per location group and 10X technology with lineage, and cell group designations

SAMD12 INO80D NBAS ARID1B AUTS2

1.19e-04199107594b94b17ca18b8dc27b91da1f2ccf89e03cc7035
ToppCellSepsis-URO|Sepsis / Disease, condition lineage and cell class

BEST1 CCDC85A B4GALT5 IRS2 MAF

1.19e-0419910758e6dac82d1d0e759cd567f9c95b70cb4801d7caf
ToppCellSigmoid-(1)_T_cell-(16)_Tfh|Sigmoid / shred on region, Cell_type, and subtype

SATB1 OR51M1 HELZ2 NLRC5 TTC39A

1.19e-041991075a61bf52d2d359746433623ee00337124f1f84f61
ToppCellBrain_organoid-organoid_Paulsen_bioRxiv-1_mon-Proliferating-Cycling_Progenitors|1_mon / Sample Type, Dataset, Time_group, and Cell type.

WRNIP1 MAN1A2 USP42 GLI3 IRS2

1.19e-041991075358c4b3037f59378db8916a2fbe9ed4830cf1449
ToppCellLung_Parenchyma-Control-Endothelial-Endothelial-Endothelial-2|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

CCDC85A SHROOM4 SOX7 HEY1 SP6

1.19e-041991075dfd60380a29f99e187050933ee5252ec11c68a32
ToppCellParenchyma_COVID-19-Endothelial-TX-Capillary|Parenchyma_COVID-19 / Sample group, Lineage and Cell type

CCDC85A SHROOM4 SOX7 STC2 HEY1

1.22e-0420010756c0498a5868891e8e22c03469d00669b20249b1a
ToppCellBronchial-10x5prime-Endothelial-Endothelia_vascular-VE_capillary|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

CCDC85A SHROOM4 SOX7 STC2 SP6

1.22e-0420010755ab588808c1fc384019413401ab4bf9bc06bf529
ToppCellLPS_IL1RA|World / Treatment groups by lineage, cell group, cell type

SH2B2 CCDC85A B4GALT5 SHROOM4 STC2

1.22e-042001075a02fa5b3c4723a6eaa3c685588666c710478dd25
ToppCellBrain_organoid-organoid_Tanaka_cellReport-10w-OPC_related|10w / Sample Type, Dataset, Time_group, and Cell type.

PHLDA1 GLIS3 POU3F2 IGFBPL1 SATB1

1.22e-0420010758f5d98f962ddd8c4658c89ff8a2894de1228562a
ToppCellLung_Parenchyma-Severe-Endothelial-Endothelial-Capillary-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

CCDC85A SHROOM4 SOX7 STC2 HEY1

1.22e-0420010757020045b933cb104fb99b79524cb0d4734b8636d
ToppCellMS-Multiple_Sclerosis-Lymphocyte-T/NK-MAIT|Multiple_Sclerosis / Disease, condition lineage and cell class

LAG3 SAMD12 COL5A3 SATB1 MAF

1.22e-04200107510120f474ac3de10fc8e66158969415bd3f8c1da
ToppCellLung_Parenchyma-Severe-Endothelial-Endothelial-Capillary|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

CCDC85A SHROOM4 SOX7 STC2 HEY1

1.22e-042001075e9913511a129bb3cee85e7ebf565b951dab91542
ToppCellBrain_organoid-organoid_Tanaka_cellReport-3m-Neuronal-Neuron|3m / Sample Type, Dataset, Time_group, and Cell type.

PHLDA1 POU3F2 POU3F3 IGFBPL1 FAM149A

1.22e-0420010753d134ae3c48ff4d1849db4fbe44ff73fb6c8c779
ToppCellBrain_organoid-organoid_Tanaka_cellReport-10w-OPC_related-Oligodendrocyte/OPC|10w / Sample Type, Dataset, Time_group, and Cell type.

PHLDA1 GLIS3 POU3F2 IGFBPL1 SATB1

1.22e-042001075345f1eac498cc87fd7bf08e7312608b2d6fe1dd7
ToppCellBrain_organoid-organoid_Tanaka_cellReport-10w-Neuronal-Neuron|10w / Sample Type, Dataset, Time_group, and Cell type.

KALRN PHLDA1 POU3F2 IGFBPL1 CITED2

1.22e-042001075332905a686356cd1e024d40679be98e9d8b1b5e8
ToppCellCOVID-19-COVID-19_Mild-Lymphocyte-T/NK-MAIT|COVID-19_Mild / Disease, condition lineage and cell class

PHLDA1 LAG3 COL5A3 SATB1 MAF

1.22e-04200107545b2a84d5a325f551205ae31c164d2de7773d3b6
Diseaseserum gamma-glutamyl transferase measurement

SEC16B KALRN BICRA UGT1A6 LAG3 GLIS3 PMEPA1 SOX7 FBXO42 PRRC2A SPATA13 KLB

7.61e-0591410212EFO_0004532
Diseasetriglycerides:total lipids ratio, very low density lipoprotein cholesterol measurement

SEC16B PMEPA1 SEC16A HELZ2 SP6 NLRC5

1.35e-042251026EFO_0008317, EFO_0020947
Diseasebody fat percentage

SEC16B IRS1 PMEPA1 ENAM MTMR11 SP6 AUTS2 PRRC2A

2.98e-044881028EFO_0007800
Diseasebipolar disorder, schizophrenia

KLF16 NLRC5 MAF

4.17e-04421023MONDO_0004985, MONDO_0005090
Diseaseamnestic disorder (implicated_via_orthology)

IRS1 IRS2

4.19e-0491022DOID:10914 (implicated_via_orthology)
Diseaseglucagon-like peptide-1 measurement

BICRA ENAM

5.23e-04101022EFO_0008465
Diseasesleep apnea measurement

HECW1 DNM1P46 INO80D ARID1B

7.16e-041161024EFO_0007817
Diseasetriglycerides:total lipids ratio, high density lipoprotein cholesterol measurement

DGKQ PMEPA1 DDB2 SP6 NLRC5

7.60e-042061025EFO_0004612, EFO_0020947
Diseasesleep duration, high density lipoprotein cholesterol measurement

PMEPA1 DDB2 SP6 NLRC5

8.39e-041211024EFO_0004612, EFO_0005271
DiseaseDiabetes Mellitus, Non-Insulin-Dependent

INPPL1 GLIS3 IRS1 AUTS2 IRS2

1.04e-032211025C0011860
DiseaseGDH/6PGL endoplasmic bifunctional protein measurement

ERGIC2 AHSG

1.05e-03141022EFO_0801619
Diseasevery low density lipoprotein cholesterol measurement, cholesterol:total lipids ratio

SEC16B SEC16A HELZ2 SP6 NLRC5

1.06e-032221025EFO_0008317, EFO_0020943
Diseaseage at menarche

SEC16B POU3F2 CCDC85A KLF16 SATB1 ZIC5 SKOR2 SP6

1.08e-035941028EFO_0004703
Diseasewaist-hip ratio

SEC16B MYCBP2 CUL9 DGKQ COL5A3 TSEN2 KIDINS220 STC2 GLI3 SP6 TTC39A ABCC10

1.08e-03122610212EFO_0004343
Diseasearm span

POU3F2 AUTS2

1.21e-03151022EFO_0005108
Diseaseleptin measurement, type 2 diabetes mellitus

GLIS3 SP6

1.38e-03161022EFO_0005000, MONDO_0005148
Diseaseankle brachial index

NBAS ARID1B

1.38e-03161022EFO_0003912
Diseaseaspartate aminotransferase measurement, serum alanine aminotransferase measurement, low density lipoprotein triglyceride measurement, body fat percentage, high density lipoprotein cholesterol measurement, sex hormone-binding globulin measurement

SEC16B PMEPA1 MTMR11 SP6 AUTS2 PRRC2A

1.69e-033641026EFO_0004612, EFO_0004696, EFO_0004735, EFO_0004736, EFO_0007800, EFO_0009946
DiseaseDrugs used in diabetes use measurement

ATG16L1 MYCBP2 GLIS3 SP6 AUTS2

1.95e-032551025EFO_0009924
Diseasep-tau measurement

GLIS3 IRS1 AUTS2

2.01e-03721023EFO_0004763
Diseaseglucose measurement

MYCBP2 GLIS3 GLI3 NFX1 AUTS2 APBB1IP

2.09e-033801026EFO_0004468
Diseasevery low density lipoprotein cholesterol measurement, cholesteryl esters:total lipids ratio

SEC16B SEC16A HELZ2 SP6 NLRC5

2.27e-032641025EFO_0008317, EFO_0020944
Diseasecortical surface area measurement

MYCBP2 PPFIA1 GLIS3 CUL9 POU3F3 PMEPA1 ARID1B MTMR11 GLI3 FBXO42 AUTS2 PRRC2A

2.35e-03134510212EFO_0010736
Diseaseinsulin measurement

GLIS3 IRS1 CCDC85A SP6 IRS2

2.38e-032671025EFO_0004467
Diseaseosteoporosis (biomarker_via_orthology)

IRS1 IRS2

2.61e-03221022DOID:11476 (biomarker_via_orthology)
Diseasecholesterol:total lipids ratio, high density lipoprotein cholesterol measurement

SEC16B DGKQ DDB2 SP6 NLRC5

2.75e-032761025EFO_0004612, EFO_0020943
DiseaseSensorineural Hearing Loss (disorder)

GLIS3 LRP2

2.86e-03231022C0018784
Diseasetype 2 diabetes mellitus (is_implicated_in)

INPPL1 IRS1 AHSG IRS2

2.98e-031711024DOID:9352 (is_implicated_in)
Diseasenon-high density lipoprotein cholesterol measurement

UGT1A6 GLIS3 DGKQ ERGIC2 ENAM SP6 ZNF579 MAF

3.34e-037131028EFO_0005689
Diseasepulmonary embolism

SP6 FGG

3.37e-03251022EFO_0003827
Diseaseresponse to peginterferon alfa-2a

GLIS3 NBAS

3.37e-03251022EFO_0010103
Diseasevery low density lipoprotein cholesterol measurement, phospholipids:total lipids ratio

DGKQ HELZ2 SP6 AHSG NLRC5

3.45e-032911025EFO_0008317, EFO_0020946

Protein segments in the cluster

PeptideGeneStartEntry
DRHRHGPHAHSPELQ

SLC4A9

366

Q96Q91
NVHAPPHGDQGVHLL

DNM1P46

91

Q6ZS02
HDVPNRHEISPGHDG

ATG16L1

61

Q676U5
KAIPHPRGHAHLAAL

ERGIC2

191

Q96RQ1
ALGNHHDPAVPRAPH

APBB1IP

496

Q7Z5R6
FLPPCAQLLHERHHG

AP1G2

176

O75843
AALRAHHIPEDPGHL

DGKQ

331

P52824
GRFLGLQSHDHHPPR

BEST1

391

O76090
GGLNSVHHHPLLPRH

ARID1B

66

Q8NFD5
SGHLPIHVAADRGHL

ASB14

281

A6NK59
HRLGAGKTPHLGEPH

CCDC87

661

Q9NVE4
SIPHHHRGEVQFLGR

B4GALT5

326

O43286
HPAAGHDGAQPLRVL

FAM90A10

381

A6NDY2
HIHHQDGAPSLPGQD

ASTN1

121

O14525
RQHPGSHVHGPRLVI

ABHD16B

161

Q9H3Z7
QLRHPSVITGPHGHA

RBM20

136

Q5T481
HHLGVVPPRGVLLHG

NVL

291

O15381
HPAAGHDGAQPLRVL

FAM90A7

381

A6NKC0
PGPKCHIHSDGHRHR

OBSL1

1581

O75147
GHSLPPIARRLGHHP

FBXO42

611

Q6P3S6
VLAHSPHGHSRGPLA

ABCC10

121

Q5T3U5
HGEPARRASHNELPH

KIDINS220

1301

Q9ULH0
FHPPVPIDARHHEGR

GLI3

131

P10071
GYGRRHLQPHDAPGH

GLI3

986

P10071
HLQPHDAPGHGVRRA

GLI3

991

P10071
HLAKHARRHPGFHPD

KLF16

201

Q9BXK1
LHPHHAAGGLHFDDR

MAF

246

O75444
NRFPHVLVPHAHADG

FAM149A

496

A5PLN7
FHQGRGPRLSWHHPG

MTMR11

251

A4FU01
GKHSIFPALPHHGQE

HECW1

236

Q76N89
SLVHRFGKHAPPAIH

OR51M1

271

Q9H341
HIHHLLGNPEFAAPE

KALRN

2836

O60229
FGAIHHPHDLARPST

AUTS2

696

Q8WXX7
RLHSVHPASLDGHLP

AUTS2

1166

Q8WXX7
PRAHPGHLHKARDGP

IGFBPL1

136

Q8WX77
PPKQEGHRHTNAGHR

NFX1

261

Q12986
LHHGRPHLGSVPDFR

PPFIA1

521

Q13136
RGQGRVPVRESPHHH

LAG3

206

P18627
GHHRHTVYDGALPHP

LRP2

3396

P98164
HSPARRFGGPVHHQA

ELAVL1

201

Q15717
DCPLGLIPHPHRHFQ

DDB2

321

Q92466
CGARLEPSLPHPHHQ

IRS1

821

P35568
PHGINTAIYHPGHRL

NBAS

236

A2RRP1
LHHLLPDHAPGQSVA

NLRC5

416

Q86WI3
GPPSLLEGTRLHHTH

PMEPA1

251

Q969W9
LREPPDHGELGSHHC

POU3F4

166

P49335
HDPKLHHPSQGFRFG

GRIN3A

781

Q8TCU5
PISVPGARRHHHLVN

IRS2

316

Q9Y4H2
GARRHHHLVNLPPSQ

IRS2

321

Q9Y4H2
HHLGGAKQVRPEHPA

FGG

426

P02679
WHLGHRPQFHPLKHG

GALNS

141

P34059
QHPGGLHPHNVRLFM

CDK15

191

Q96Q40
DSHVLLAAPPGHQLH

AHSG

296

P02765
HHGLVERPSRNRFHP

CRTC3

91

Q6UUV7
AHLHHPELGPHAQQL

GLIS3

311

Q8NEA6
PEHARHSGGSPEHLQ

CCDC85A

326

Q96PX6
NPGVFLIHGPDEHRH

MAN1A2

86

O60476
GLHDGSHASQRPHPA

INO80D

786

Q53TQ3
HAHLGLPEPLLHADG

KLB

646

Q86Z14
TEPHHQGRLGSAHPE

HEY1

211

Q9Y5J3
LRIHPHPGADHGEGR

KNCN

76

A6PVL3
HEGQDFPHGGVLRLH

CUL9

1821

Q8IWT3
GRQEEHLPHPSHGSR

ENAM

581

Q9NRM1
GDRVPLSLHLGHHLH

HELZ2

1571

Q9BYK8
LGPVLAPHSGAHSAH

BICRA

526

Q9NZM4
RVHNPGHSHVHLPER

SLC39A10

271

Q9ULF5
GHSHVHLPERNGHDP

SLC39A10

276

Q9ULF5
HLPERNGHDPGRGHQ

SLC39A10

281

Q9ULF5
DDLHAGTALHHRGPP

POU3F3

156

P20264
GLVCHELHRNHPHLP

COL5A3

1541

P25940
SHFILVGLHHPPQLG

OR10G6

31

Q8NH81
HRFGGHTIPPSLHII

OR52N5

271

Q8NH56
ARALPPDAHHLHAER

MMP11

31

P24347
PDAHHLHAERRGPQP

MMP11

36

P24347
HDPKLHHPAQGFRFG

GRIN3B

681

O60391
HFHELHLGLGCPPNH

PLAC1

51

Q9HBJ0
RHFLAHHPDGPHFGR

SZT2

3076

Q5T011
QHIGLLHPGDRGPDH

TSEN2

241

Q8NCE0
EEHGHPRRIPHLPGH

SOX7

226

Q9BT81
PLPPAHHVEDSRHRG

TAGAP

636

Q8N103
LESGPKNGERVHHHP

HPS3

211

Q969F9
FSAPRHGHLGFLPHK

RPL3L

6

Q92901
PDSKLHHGHDPRGGL

PRRC2A

221

P48634
VPAPQLGHHRHPRVG

INPPL1

1021

O15357
HLIGPTGHRHSAPEQ

SHROOM4

401

Q9ULL8
LHCGLNPRGIDHPAH

SAMD12

6

Q8N8I0
IAGEAAHPLPHTFHR

MYCBP2

3641

O75592
HHLLPAAGGQHLLGP

SP6

171

Q3SY56
QPAGLHHHGLRDAHD

POU3F2

206

P20265
SNAVHHHGDRPPHII

SATB1

571

Q01826
HHGDRPPHIIHVPAE

SATB1

576

Q01826
GRFPDGTNGLHHHPA

CITED2

11

Q99967
GHPSRAHHLRQTLPG

RNF31

246

Q96EP0
VAPPHQGLHPIHQRH

SPATA13

601

Q96N96
NPPDRHRGHGKIHLQ

SCN2B

131

O60939
QDRHAPEHHPGHGDR

USP42

991

Q9H9J4
HLLTHGGPRPHHCTQ

ZSCAN10

541

Q96SZ4
LHQGPGHEQHSPLVA

SEC16A

256

O15027
HPQPHSQPHGHRLLR

PHLDA1

381

Q8WV24
RHRPLLHALEPAGHN

STPG3

306

Q8N7X2
RAHHGEAGHHLPEPS

STC2

236

O76061
LAAHRLTHSGARPHP

ZNF575

106

Q86XF7
LRHFHTHPIPLESGG

SH2B2

491

O14492
GHHRPVPHSWHNGER

SEC16B

31

Q96JE7
AELAGAPHAHHKRPR

SKOR2

296

Q2VWA4
GSRVPAPHHPHLLEG

SKOR2

596

Q2VWA4
APHHPHLLEGRKAGG

SKOR2

601

Q2VWA4
LLHPAGHAEPAAGSH

WRNIP1

41

Q96S55
RPRHPHHHQTFAGKD

TESPA1

506

A2RU30
PLPAHGSHLDHRIPA

PLEKHG2

1111

Q9H7P9
HPEPRTAHLHFPAAG

VWA3B

1241

Q502W6
RHKGAPHLRPAAHDL

UGT1A6

466

P19224
PGHNFVRHHLRNRPD

YIPF2

106

Q9BWQ6
ADRLLHGQALHDPPH

UPK3B

266

Q9BT76
HLSRHLRGHGPQPPL

ZNF579

86

Q8NAF0
HGGAVRPRALHDPSH

TTC39A

146

Q5SRH9
HHSLTAHGAPERPLA

ZNF219

206

Q9P2Y4
HQHHPHLPGAAGAFL

ZIC5

371

Q96T25
LAPLLRHQHRHGVEP

ZNF784

141

Q8NCA9