Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionpore-forming activity

DEFA1 DEFA3 DEFA4 PRF1

1.48e-07101054GO:0140911
GeneOntologyMolecularFunctiontransporter activity

ATP13A4 SLC38A4 SLC22A23 SLC26A5 SLC44A2 XKR8 SLC10A3 PKD1L2 SLC44A4 SLC7A14 SLC38A2 NALCN ABCA6 TRPM3 SLC2A6 PRF1 PKD1 TRPV6 TMEM41B SLC24A1 GRAMD1C ATP2B4

7.61e-07128910522GO:0005215
GeneOntologyMolecularFunctiontransmembrane transporter activity

ATP13A4 SLC38A4 SLC22A23 SLC26A5 SLC44A2 SLC10A3 PKD1L2 SLC44A4 SLC7A14 SLC38A2 NALCN ABCA6 TRPM3 SLC2A6 PRF1 PKD1 TRPV6 SLC24A1 ATP2B4

1.13e-05118010519GO:0022857
GeneOntologyMolecularFunctioncalcium ion transmembrane transporter activity

ATP13A4 PKD1L2 TRPM3 PKD1 TRPV6 SLC24A1 ATP2B4

1.51e-051511057GO:0015085
GeneOntologyMolecularFunctionmetal ion transmembrane transporter activity

ATP13A4 SLC38A4 SLC10A3 PKD1L2 SLC38A2 NALCN TRPM3 PKD1 TRPV6 SLC24A1 ATP2B4

3.38e-0546510511GO:0046873
GeneOntologyMolecularFunctiontransmembrane signaling receptor activity

HTR4 TMEM116 GPR37 DDR2 GPR85 TMIGD3 LMBR1 CLEC4M TAS2R42 CELSR1 OR51I1 OR6C76 PKD1 OR1P1 TAS2R40 ACKR2 TAS2R39 GPRC5B EPHB1

7.36e-05135310519GO:0004888
GeneOntologyMolecularFunctionalanine:sodium symporter activity

SLC38A4 SLC38A2

1.63e-0441052GO:0015655
GeneOntologyMolecularFunctionactive transmembrane transporter activity

ATP13A4 SLC38A4 SLC26A5 SLC44A2 SLC10A3 SLC44A4 SLC38A2 ABCA6 SLC24A1 ATP2B4

2.09e-0447710510GO:0022804
GeneOntologyMolecularFunctionG protein-coupled receptor activity

HTR4 TMEM116 GPR37 GPR85 TMIGD3 TAS2R42 CELSR1 OR51I1 OR6C76 OR1P1 TAS2R40 ACKR2 TAS2R39 GPRC5B

2.17e-0488410514GO:0004930
GeneOntologyMolecularFunctionbitter taste receptor activity

TAS2R42 TAS2R40 TAS2R39

3.77e-04271053GO:0033038
GeneOntologyMolecularFunctionsignaling receptor regulator activity

DEFB104A CXCL14 PF4V1 IFNA2 BGLAP THPO EFNA5 ASIP IGSF1 DEFB109B GNRH2

3.98e-0461610511GO:0030545
GeneOntologyMolecularFunctioninorganic cation transmembrane transporter activity

ATP13A4 SLC38A4 SLC10A3 PKD1L2 SLC38A2 NALCN TRPM3 PKD1 TRPV6 SLC24A1 ATP2B4

4.61e-0462710511GO:0022890
GeneOntologyMolecularFunctioncalcium channel activity

PKD1L2 TRPM3 PKD1 TRPV6 SLC24A1

6.00e-041291055GO:0005262
GeneOntologyMolecularFunctionreceptor ligand activity

DEFB104A CXCL14 PF4V1 IFNA2 BGLAP THPO EFNA5 ASIP DEFB109B GNRH2

6.15e-0454710510GO:0048018
GeneOntologyMolecularFunctioninorganic molecular entity transmembrane transporter activity

ATP13A4 SLC38A4 SLC26A5 SLC10A3 PKD1L2 SLC38A2 NALCN TRPM3 PKD1 TRPV6 SLC24A1 ATP2B4

6.32e-0475810512GO:0015318
GeneOntologyMolecularFunctionsignaling receptor activator activity

DEFB104A CXCL14 PF4V1 IFNA2 BGLAP THPO EFNA5 ASIP DEFB109B GNRH2

6.79e-0455410510GO:0030546
GeneOntologyMolecularFunctiontaste receptor activity

TAS2R42 TAS2R40 TAS2R39

6.87e-04331053GO:0008527
GeneOntologyMolecularFunctionmonoatomic cation transmembrane transporter activity

ATP13A4 SLC38A4 SLC10A3 PKD1L2 SLC38A2 NALCN TRPM3 PKD1 TRPV6 SLC24A1 ATP2B4

7.42e-0466410511GO:0008324
GeneOntologyMolecularFunctioncholine transmembrane transporter activity

SLC44A2 SLC44A4

7.51e-0481052GO:0015220
GeneOntologyMolecularFunctionneutral L-amino acid:sodium symporter activity

SLC38A4 SLC38A2

7.51e-0481052GO:0005295
GeneOntologyMolecularFunctionorganic acid:sodium symporter activity

SLC38A4 SLC10A3 SLC38A2

8.18e-04351053GO:0005343
GeneOntologyMolecularFunctionorganic anion transmembrane transporter activity

SLC38A4 SLC26A5 SLC10A3 SLC44A4 SLC7A14 SLC38A2 SLC2A6

9.11e-042931057GO:0008514
GeneOntologyMolecularFunctionmonoatomic ion transmembrane transporter activity

ATP13A4 SLC38A4 SLC26A5 SLC10A3 PKD1L2 SLC38A2 NALCN TRPM3 PKD1 TRPV6 SLC24A1 ATP2B4

9.37e-0479310512GO:0015075
GeneOntologyMolecularFunctionorganic cation transmembrane transporter activity

SLC38A4 SLC44A2 SLC44A4 SLC38A2

9.64e-04831054GO:0015101
GeneOntologyMolecularFunctionsecondary active transmembrane transporter activity

SLC38A4 SLC26A5 SLC44A2 SLC10A3 SLC44A4 SLC38A2 SLC24A1

9.67e-042961057GO:0015291
GeneOntologyMolecularFunctionactive monoatomic ion transmembrane transporter activity

ATP13A4 SLC38A4 SLC26A5 SLC10A3 SLC38A2 SLC24A1 ATP2B4

1.07e-033011057GO:0022853
GeneOntologyMolecularFunctionP-type calcium transporter activity

ATP13A4 ATP2B4

1.46e-03111052GO:0005388
GeneOntologyMolecularFunctionplatelet-derived growth factor binding

COL1A1 COL1A2

1.75e-03121052GO:0048407
GeneOntologyMolecularFunctionsodium ion transmembrane transporter activity

SLC38A4 SLC10A3 SLC38A2 NALCN SLC24A1

2.10e-031711055GO:0015081
GeneOntologyMolecularFunctionalanine transmembrane transporter activity

SLC38A4 SLC38A2

3.13e-03161052GO:0022858
GeneOntologyMolecularFunctionlipid transporter activity

XKR8 SLC10A3 ABCA6 TMEM41B GRAMD1C

3.79e-031961055GO:0005319
GeneOntologyBiologicalProcessdisruption of plasma membrane integrity in another organism

DEFA1 DEFA3 DEFA4

2.54e-0661053GO:0051673
GeneOntologyBiologicalProcessdisruption of cellular anatomical structure in another organism

DEFA1 DEFA3 DEFA4

2.54e-0661053GO:0140975
GeneOntologyBiologicalProcessorthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis

VANGL2 CELSR1

2.57e-0521052GO:0060488
GeneOntologyBiologicalProcessplanar dichotomous subdivision of terminal units involved in lung branching morphogenesis

VANGL2 CELSR1

2.57e-0521052GO:0060489
GeneOntologyBiologicalProcesslateral sprouting involved in lung morphogenesis

VANGL2 CELSR1

2.57e-0521052GO:0060490
GeneOntologyBiologicalProcessplasma kallikrein-kinin cascade

F12 PRCP

7.68e-0531052GO:0002353
GeneOntologyBiologicalProcessdichotomous subdivision of terminal units involved in lung branching

VANGL2 CELSR1

7.68e-0531052GO:0060448
GeneOntologyBiologicalProcesscell chemotaxis

GBF1 DEFB104A CXCL14 PF4V1 ITGA1 DEFA1 ACKR2 DEFB109B EPHB1

9.98e-053631059GO:0060326
GeneOntologyBiologicalProcessimmunological synapse formation

DOCK8 PRF1 EPHB1

1.17e-04191053GO:0001771
GeneOntologyBiologicalProcessestablishment of body hair planar orientation

VANGL2 CELSR1

1.53e-0441052GO:0048105
GeneOntologyBiologicalProcessestablishment of body hair or bristle planar orientation

VANGL2 CELSR1

1.53e-0441052GO:0048104
GeneOntologyBiologicalProcesscalcium ion transmembrane transport

ATP13A4 PKD1L2 NALCN TRPM3 PKD1 UBR3 TRPV6 SLC24A1 ATP2B4

1.78e-043921059GO:0070588
GeneOntologyBiologicalProcessG protein-coupled receptor signaling pathway

HTR4 TMEM116 GPR37 GPR85 TMIGD3 PF4V1 ADM5 TAS2R42 CELSR1 THPO OR51I1 OR6C76 OR1P1 TAS2R40 ACKR2 TAS2R39 ATP2B4 GPRC5B

2.25e-04139510518GO:0007186
GeneOntologyBiologicalProcesshumoral immune response

SUSD4 CXCL14 PF4V1 IFNA2 DEFA1 DEFA3 DEFA4 RNASE4

2.38e-043211058GO:0006959
GeneOntologyBiologicalProcessdefense response to other organism

SUSD4 DDX60 DEFB104A CXCL14 PF4V1 SIRPA CLEC4M IFNA2 F12 CD84 DEFA1 DEFA3 DEFA4 RNASE4 PRF1 DDX60L LY9 DEFB109B

2.49e-04140710518GO:0098542
GeneOntologyBiologicalProcessdefense response to symbiont

SUSD4 DDX60 DEFB104A CXCL14 PF4V1 SIRPA CLEC4M IFNA2 F12 CD84 DEFA1 DEFA3 DEFA4 RNASE4 PRF1 DDX60L LY9

2.59e-04128610517GO:0140546
GeneOntologyBiologicalProcesscalcium ion transport

ATP13A4 PKD1L2 CD84 NALCN TRPM3 PKD1 UBR3 TRPV6 SLC24A1 ATP2B4

2.72e-0450910510GO:0006816
GeneOntologyBiologicalProcessresponse to mechanical stimulus

DDR2 SLC26A5 PKD1L2 BGLAP SLC38A2 PKD1 COL1A1

2.73e-042471057GO:0009612
GeneOntologyBiologicalProcesschemotaxis

GBF1 DEFB104A CXCL14 PF4V1 ITGA1 DEFA1 EFNA5 ACKR2 DEFB109B EPHB1

3.08e-0451710510GO:0006935
GeneOntologyBiologicalProcesstaxis

GBF1 DEFB104A CXCL14 PF4V1 ITGA1 DEFA1 EFNA5 ACKR2 DEFB109B EPHB1

3.17e-0451910510GO:0042330
GeneOntologyBiologicalProcessnegative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains

HFE SUSD4 PF4V1 IFNA2

3.59e-04661054GO:0002823
GeneOntologyBiologicalProcesskinin cascade

F12 PRCP

3.80e-0461052GO:0002254
GeneOntologyBiologicalProcessantimicrobial humoral response

CXCL14 PF4V1 DEFA1 DEFA3 DEFA4 RNASE4

3.81e-041861056GO:0019730
GeneOntologyBiologicalProcessinnate immune response in mucosa

DEFA1 DEFA3 DEFA4

4.71e-04301053GO:0002227
GeneOntologyBiologicalProcessnegative regulation of adaptive immune response

HFE SUSD4 PF4V1 IFNA2

4.74e-04711054GO:0002820
GeneOntologyBiologicalProcessleukocyte migration

GBF1 DOCK8 DEFB104A TMIGD3 CXCL14 PF4V1 SIRPA ITGA1 DEFA1

4.81e-044491059GO:0050900
GeneOntologyBiologicalProcesskilling of cells of another organism

CXCL14 DEFA1 DEFA3 DEFA4 PRF1

5.19e-041291055GO:0031640
GeneOntologyBiologicalProcessdisruption of cell in another organism

CXCL14 DEFA1 DEFA3 DEFA4 PRF1

5.19e-041291055GO:0141061
GeneOntologyCellularComponentcollagen type I trimer

COL1A1 COL1A2

2.69e-0521092GO:0005584
GeneOntologyCellularComponentcell surface

HFE GPR37 DLK1 SIRPA ITGA1 CLEC4M CD84 EFNA5 PROM2 PKD1 CD53 ACKR2 LY9 SLC24A1 GPRC5B

6.46e-04111110915GO:0009986
GeneOntologyCellularComponentsecretory granule

SPINK2 EQTN SLC44A2 PF4V1 SIRPA ITGA1 POMT1 HUWE1 DEFA1 DEFA3 DEFA4 PRCP CD53 COL1A1

7.98e-04101410914GO:0030141
GeneOntologyCellularComponentbasal part of cell

HFE SLC26A5 ITGA1 VANGL2 PROM2 PRCP PKD1 ATP2B4

8.25e-043781098GO:0045178
HumanPhenoBiconcave flattened vertebrae

COL1A1 COL1A2

3.58e-052312HP:0003321
HumanPhenoAbsent ossification of calvaria

COL1A1 COL1A2

3.58e-052312HP:0005623
HumanPhenoSevere generalized osteoporosis

COL1A1 COL1A2

3.58e-052312HP:0005897
HumanPhenoFemoral bowing present at birth, straightening with time

COL1A1 COL1A2

3.58e-052312HP:0005005
HumanPhenoEpiphyseal stippling

DDR2 DLK1 COL1A1 COL1A2

8.81e-0540314HP:0010655
HumanPhenoCalcific stippling

DDR2 DLK1 COL1A1 COL1A2

9.72e-0541314HP:0002832
HumanPhenoPopcorn calcification

COL1A1 COL1A2

1.07e-043312HP:6000871
HumanPhenoBowing of limbs due to multiple fractures

COL1A1 COL1A2

2.13e-044312HP:0003023
HumanPhenoUndulate ribs

DLK1 TRPV6

2.13e-044312HP:0010561
HumanPhenoSubperiosteal bone formation

TRPV6 COL1A1

2.13e-044312HP:0031485
DomainDefensin_propep

DEFA1 DEFA3 DEFA4

1.62e-0651033PF00879
DomainAlpha-defensin

DEFA1 DEFA3 DEFA4

1.62e-0651033IPR006081
DomainDefensin_1

DEFA1 DEFA3 DEFA4

1.62e-0651033PF00323
DomainAlpha-defensin_pro

DEFA1 DEFA3 DEFA4

1.62e-0651033IPR016327
DomainDEFENSIN

DEFA1 DEFA3 DEFA4

1.62e-0651033PS00269
DomainDefensin_propep

DEFA1 DEFA3 DEFA4

1.62e-0651033IPR002366
DomainDefensin_beta/alpha

DEFA1 DEFA3 DEFA4

8.94e-0681033IPR006080
DomainDEFSN

DEFA1 DEFA3 DEFA4

8.94e-0681033SM00048
DomainREJ

PKD1L2 PKD1

1.79e-0441032PS51111
DomainREJ_dom

PKD1L2 PKD1

1.79e-0441032IPR014010
Domain-

PM20D1 CNDP1

2.98e-04510323.30.70.360
DomainM20_dimer

PM20D1 CNDP1

2.98e-0451032PF07687
DomainPeptidase_M20_dimer

PM20D1 CNDP1

2.98e-0451032IPR011650
DomainPeptidase_M20

PM20D1 CNDP1

2.98e-0451032PF01546
DomainPeptidase_M20

PM20D1 CNDP1

2.98e-0451032IPR002933
DomainCholine_transpo

SLC44A2 SLC44A4

2.98e-0451032PF04515
DomainCholine_transptr-like

SLC44A2 SLC44A4

2.98e-0451032IPR007603
DomainProt_inh_Kazal-m

SPINK2 SPINK9

2.98e-0451032IPR001239
DomainTAS2R

TAS2R42 TAS2R40 TAS2R39

3.86e-04261033PF05296
DomainT2R

TAS2R42 TAS2R40 TAS2R39

3.86e-04261033IPR007960
DomainPKD/REJ-like

PKD1L2 PKD1

4.45e-0461032IPR002859
DomainREJ

PKD1L2 PKD1

4.45e-0461032PF02010
DomainGPS

PKD1L2 CELSR1 PKD1

8.61e-04341033SM00303
DomainGPS

PKD1L2 CELSR1 PKD1

9.38e-04351033PF01825
DomainGPS

PKD1L2 CELSR1 PKD1

1.02e-03361033PS50221
DomainGPS

PKD1L2 CELSR1 PKD1

1.10e-03371033IPR000203
DomainFib_collagen_C

COL1A1 COL1A2

1.60e-03111032IPR000885
DomainCOLFI

COL1A1 COL1A2

1.60e-03111032PF01410
DomainPKD_channel

PKD1L2 PKD1

1.60e-03111032PF08016
DomainNC1_FIB

COL1A1 COL1A2

1.60e-03111032PS51461
DomainFib_collagen_C

COL1A1 COL1A2

1.60e-03111032PD002078
DomainCOLFI

COL1A1 COL1A2

1.60e-03111032SM00038
DomainPKD1_2_channel

PKD1L2 PKD1

1.60e-03111032IPR013122
DomainChemokine_CXC

CXCL14 PF4V1

3.44e-03161032IPR001089
DomainSMALL_CYTOKINES_CXC

CXCL14 PF4V1

3.88e-03171032PS00471
DomainAa_trans

SLC38A4 SLC38A2

3.88e-03171032PF01490
DomainAA_transpt_TM

SLC38A4 SLC38A2

3.88e-03171032IPR013057
DomainLH2

PKD1L2 PKD1

4.35e-03181032SM00308
DomainCation_ATPase_N

ATP13A4 ATP2B4

4.35e-03181032PF00690
DomainCation_ATPase_N

ATP13A4 ATP2B4

4.35e-03181032SM00831
DomainKAZAL_1

SPINK2 SPINK9

4.35e-03181032PS00282
DomainATPase_P-typ_cation-transptr_N

ATP13A4 ATP2B4

4.84e-03191032IPR004014
DomainPLAT

PKD1L2 PKD1

5.91e-03211032PS50095
Domain-

PKD1L2 PKD1

5.91e-032110322.60.60.20
DomainPLAT

PKD1L2 PKD1

5.91e-03211032PF01477
DomainPLAT/LH2_dom

PKD1L2 PKD1

5.91e-03211032IPR001024
PathwayREACTOME_DEFENSINS

DEFB104A DEFA1 DEFA3 DEFA4 DEFB109B

9.97e-0653775M557
PathwayREACTOME_ALPHA_DEFENSINS

DEFA1 DEFA3 DEFA4

1.83e-0510773M26955
PathwayREACTOME_ALPHA_DEFENSINS

DEFA1 DEFA3 DEFA4

2.51e-0511773MM14569
PathwayREACTOME_TRANSPORT_OF_SMALL_MOLECULES

HFE ATP13A4 SLC38A4 SLC44A2 SLC44A4 SLC38A2 NALCN ABCA6 TRPM3 SLC2A6 TRPV6 SLC24A1 ATP2B4

7.33e-056817713MM14985
PathwayREACTOME_PLATELET_ADHESION_TO_EXPOSED_COLLAGEN

ITGA1 COL1A1 COL1A2

8.34e-0516773M9450
PathwayREACTOME_DISEASES_OF_HEMOSTASIS

F12 COL1A1 COL1A2

1.43e-0419773M48230
PathwayREACTOME_TRANSPORT_OF_SMALL_MOLECULES

HFE ATP13A4 SLC38A4 SLC44A2 SLC44A4 SLC38A2 NALCN ABCA6 TRPM3 SLC2A6 TRPV6 SLC24A1 ATP2B4

1.60e-047367713M27287
PathwayREACTOME_ANTIMICROBIAL_PEPTIDES

DEFB104A DEFA1 DEFA3 DEFA4 DEFB109B

1.95e-0498775M27627
PathwayREACTOME_HEMOSTASIS

DOCK8 PF4V1 SIRPA ITGA1 IFNA2 F12 CD84 THPO PRCP ATP2B4 COL1A1 COL1A2

2.92e-046797712M8395
PathwayPID_LYMPH_ANGIOGENESIS_PATHWAY

ITGA1 COL1A1 COL1A2

3.31e-0425773M274
PathwayPID_INTEGRIN1_PATHWAY

ITGA1 TGFBI COL1A1 COL1A2

4.59e-0466774M18
PathwayWP_ANGIOTENSIN_II_RECEPTOR_TYPE_1_PATHWAY

F12 COL1A1 COL1A2

4.65e-0428773M42541
PathwayREACTOME_ENHANCED_BINDING_OF_GP1BA_VARIANT_TO_VWF_MULTIMER_COLLAGEN

COL1A1 COL1A2

6.08e-047772M48265
PathwayREACTOME_DEFENSINS

DEFA1 DEFA3 DEFA4

6.31e-0431773MM14568
PathwayREACTOME_NON_INTEGRIN_MEMBRANE_ECM_INTERACTIONS

DDR2 COL1A1 COL1A2

6.93e-0432773MM14924
PathwayREACTOME_DEFECTS_OF_PLATELET_ADHESION_TO_EXPOSED_COLLAGEN

COL1A1 COL1A2

8.07e-048772M48236
PathwayBIOCARTA_EPHA4_PATHWAY

ITGA1 EPHB1

1.03e-039772MM1388
PathwayREACTOME_CLASS_C_3_METABOTROPIC_GLUTAMATE_PHEROMONE_RECEPTORS

TAS2R42 TAS2R40 TAS2R39

1.07e-0337773MM15067
PathwayREACTOME_CLASS_C_3_METABOTROPIC_GLUTAMATE_PHEROMONE_RECEPTORS

TAS2R42 TAS2R40 TAS2R39

1.24e-0339773M793
PathwayREACTOME_PLATELET_AGGREGATION_PLUG_FORMATION

THPO COL1A1 COL1A2

1.24e-0339773M10735
PathwayREACTOME_FORMATION_OF_FIBRIN_CLOT_CLOTTING_CASCADE

PF4V1 F12 PRCP

1.24e-0339773M2844
PathwayREACTOME_FORMATION_OF_FIBRIN_CLOT_CLOTTING_CASCADE

PF4V1 F12 PRCP

1.24e-0339773MM14559
PathwayWP_OSTEOBLAST_SIGNALING

BGLAP COL1A1

1.29e-0310772MM15862
PathwayPID_INTEGRIN3_PATHWAY

TGFBI COL1A1 COL1A2

1.65e-0343773M53
PathwayREACTOME_CELL_SURFACE_INTERACTIONS_AT_THE_VASCULAR_WALL

PF4V1 SIRPA CD84 COL1A1 COL1A2

1.71e-03158775MM14812
PathwayREACTOME_GP1B_IX_V_ACTIVATION_SIGNALLING

COL1A1 COL1A2

1.88e-0312772MM15093
PathwayREACTOME_GP1B_IX_V_ACTIVATION_SIGNALLING

COL1A1 COL1A2

1.88e-0312772M27352
PathwayREACTOME_PLATELET_ADHESION_TO_EXPOSED_COLLAGEN

COL1A1 COL1A2

1.88e-0312772MM15452
PathwayREACTOME_SLC_MEDIATED_TRANSMEMBRANE_TRANSPORT

SLC38A4 SLC44A2 SLC44A4 SLC38A2 SLC2A6 SLC24A1

1.90e-03238776MM15076
PathwayREACTOME_GPCR_LIGAND_BINDING

HTR4 GPR37 TMIGD3 PF4V1 TAS2R42 TAS2R40 ACKR2 TAS2R39

2.35e-03430778MM15160
PathwayREACTOME_SLC_MEDIATED_TRANSMEMBRANE_TRANSPORT

SLC38A4 SLC44A2 SLC44A4 SLC38A2 SLC2A6 SLC24A1

2.38e-03249776M5988
Pubmed

DLK1 is a novel regulator of bone mass that mediates estrogen deficiency-induced bone loss in mice.

CD52 CXCL14 PF4V1 DLK1 SIRPA LAPTM5 CD84 CD53

2.00e-08145109821308776
Pubmed

Human α-defensin (DEFA) gene expression helps to characterise benign and malignant salivary gland tumours.

DEFA1 DEFA3 DEFA4

2.99e-083109323050799
Pubmed

Human neutrophil alpha-defensin 4 inhibits HIV-1 infection in vitro.

DEFA1 DEFA3 DEFA4

2.99e-083109315620707
Pubmed

The osteocalcin and collagen type I (alpha 1) promoters share common basal regulatory units.

BGLAP COL1A1 COL1A2

1.20e-07410937598807
Pubmed

Cryptdin 3 forms anion selective channels in cytoplasmic membranes of human embryonic kidney cells.

DEFA1 DEFA3 DEFA4

1.20e-074109311960772
Pubmed

The transforming growth factor-beta-inducible matrix protein (beta)ig-h3 interacts with fibronectin.

TGFBI COL1A1 COL1A2

1.20e-074109312034705
Pubmed

Type-I collagen produced by distinct fibroblast lineages reveals specific function during embryogenesis and Osteogenesis Imperfecta.

BGLAP COL1A1 COL1A2

1.20e-074109334893625
Pubmed

Genetic association analyses highlight biological pathways underlying mitral valve prolapse.

IGFBP5 COL1A1 COL1A2

2.98e-075109326301497
Pubmed

Increased gene copy number of DEFA1/DEFA3 worsens sepsis by inducing endothelial pyroptosis.

DEFA1 DEFA3 DEFA4

2.98e-075109330718392
Pubmed

Gp130-mediated signaling is necessary for normal osteoblastic function in vivo and in vitro.

BGLAP COL1A1 COL1A2

2.98e-075109314617570
Pubmed

LGR5 deficiency deregulates Wnt signaling and leads to precocious Paneth cell differentiation in the fetal intestine.

DLK1 DEFA3 DEFA4 IGFBP5

4.25e-0720109419394326
Pubmed

Mouse Paneth cell defensins: primary structures and antibacterial activities of numerous cryptdin isoforms.

DEFA1 DEFA3 DEFA4

5.95e-07610937927786
Pubmed

Development and regeneration of the neonatal digit tip in mice.

BGLAP COL1A1 COL1A2

5.95e-076109318234177
Pubmed

Structure and diversity of the murine cryptdin gene family.

DEFA1 DEFA3 DEFA4

5.95e-07610938188287
Pubmed

Strain-specific polymorphisms in Paneth cell α-defensins of C57BL/6 mice and evidence of vestigial myeloid α-defensin pseudogenes.

DEFA1 DEFA3 DEFA4

5.95e-076109321041494
Pubmed

Alpha-defensins block the early steps of HIV-1 infection: interference with the binding of gp120 to CD4.

DEFA1 DEFA3 DEFA4

5.95e-076109317132727
Pubmed

Antibacterial activity and specificity of the six human {alpha}-defensins.

DEFA1 DEFA3 DEFA4

5.95e-076109315616305
Pubmed

Enteric defensins: antibiotic peptide components of intestinal host defense.

DEFA1 DEFA3 DEFA4

5.95e-07610931500431
Pubmed

Activation of Paneth cell alpha-defensins in mouse small intestine.

DEFA1 DEFA3 DEFA4

5.95e-076109311733520
Pubmed

Cryptdins: antimicrobial defensins of the murine small intestine.

DEFA1 DEFA3 DEFA4

5.95e-07610931500163
Pubmed

Osteogenic and angiogenic profiles of the palatal process of the maxilla and the palatal process of the palatine bone.

BGLAP COL1A1 COL1A2

1.04e-067109334569061
Pubmed

A novel murine beta -defensin expressed in tongue, esophagus, and trachea.

DEFA1 DEFA3 DEFA4

1.04e-067109310922379
Pubmed

Secretion of microbicidal alpha-defensins by intestinal Paneth cells in response to bacteria.

DEFA1 DEFA3 DEFA4

1.04e-067109311248802
Pubmed

Epidermal growth factor receptor-deficient mice have delayed primary endochondral ossification because of defective osteoclast recruitment.

BGLAP COL1A1 COL1A2

1.66e-068109315456762
Pubmed

Formation and maturation of the murine meniscus.

BGLAP COL1A1 COL1A2

1.66e-068109327664939
Pubmed

Type XIII collagen strongly affects bone formation in transgenic mice.

BGLAP COL1A1 COL1A2

1.66e-068109316007336
Pubmed

Isolation and characterization of a novel plasma membrane protein, osteoblast induction factor (obif), associated with osteoblast differentiation.

BGLAP COL1A1 COL1A2

1.66e-068109320025746
Pubmed

The cell surface expression of SAP-binding receptor CD229 is regulated via its interaction with clathrin-associated adaptor complex 2 (AP-2).

CLEC4M CD84 LY9

1.66e-068109312621057
Pubmed

Molecular properties of wild-type and mutant betaIG-H3 proteins.

TGFBI COL1A1 COL1A2

1.66e-068109311867580
Pubmed

Gene polymorphisms, bone mineral density and bone mineral content in young children: the Iowa Bone Development Study.

BGLAP COL1A1 COL1A2

1.66e-068109312879219
Pubmed

Delayed osteoblastic differentiation and bone development in Cx43 knockout mice.

BGLAP COL1A1 COL1A2

2.48e-069109321934140
Pubmed

Neutral Sphingomyelinase 2 (SMPD3) Deficiency in Mice Causes Chondrodysplasia with Unimpaired Skeletal Mineralization.

BGLAP COL1A1 COL1A2

2.48e-069109331199918
Pubmed

Runx2 inhibits chondrocyte proliferation and hypertrophy through its expression in the perichondrium.

ITGA1 BGLAP COL1A1

2.48e-069109317050674
Pubmed

Genetic mapping of 40 cDNA clones on the mouse genome by PCR.

IFNA2 BGLAP DEFA1 DEFA3 DEFA4

3.04e-067110958043949
Pubmed

A quantitative analysis of the spatiotemporal pattern of transient receptor potential gene expression in the developing mouse cochlea.

PKD1L2 TRPM3 PKD1 TRPV6

3.48e-0633109419834762
Pubmed

Deletion of Tfam in Prx1-Cre expressing limb mesenchyme results in spontaneous bone fractures.

BGLAP COL1A1 COL1A2

3.54e-0610109335947192
Pubmed

Ucma is not necessary for normal development of the mouse skeleton.

BGLAP COL1A1 COL1A2

3.54e-0610109322155508
Pubmed

Rapid evolution and diversification of mammalian alpha-defensins as revealed by comparative analysis of rodent and primate genes.

DEFA1 DEFA3 DEFA4

4.85e-0611109315494476
Pubmed

ATF4 mediation of NF1 functions in osteoblast reveals a nutritional basis for congenital skeletal dysplasiae.

BGLAP COL1A1 COL1A2

6.45e-0612109317141628
Pubmed

Copy number variation of defensin genes and HIV infection in Brazilian children.

DEFB104A DEFA3 DEFA4

8.37e-0613109319194307
Pubmed

TGFbeta-mediated FGF signaling is crucial for regulating cranial neural crest cell proliferation during frontal bone development.

BGLAP COL1A1 COL1A2

8.37e-0613109316368934
Pubmed

Overexpression of BMP3 in the developing skeleton alters endochondral bone formation resulting in spontaneous rib fractures.

BGLAP COL1A1 COL1A2

8.37e-0613109319653325
Pubmed

Osteoblast Malfunction Caused by Cell Stress Response to Procollagen Misfolding in α2(I)-G610C Mouse Model of Osteogenesis Imperfecta.

BGLAP COL1A1 COL1A2

8.37e-0613109326925839
Pubmed

Neutrophil defensins enhance lung epithelial wound closure and mucin gene expression in vitro.

DEFA1 DEFA3

9.73e-062109212871849
Pubmed

[Phenotype-genotype analysis and detection of gene variant in six families with osteogenesis imperfecta].

COL1A1 COL1A2

9.73e-062109232335875
Pubmed

Molecular cloning, characterization, and chromosomal localization of the mouse homologue of CD84, a member of the CD2 family of cell surface molecules.

CD84 LY9

9.73e-062109210079287
Pubmed

Unequal Impact of COL1A1 and COL1A2 Variants on Dentinogenesis Imperfecta.

COL1A1 COL1A2

9.73e-062109236951356
Pubmed

Three arginine to cysteine substitutions in the pro-alpha (I)-collagen chain cause Ehlers-Danlos syndrome with a propensity to arterial rupture in early adulthood.

COL1A1 COL1A2

9.73e-062109217211858
Pubmed

Isolation and characterization of the cyanogen bromide peptides from the alpha 1 and alpha 2 chains of human skin collagen.

COL1A1 COL1A2

9.73e-06210925529814
Pubmed

Analysis of the COL1A1 and COL1A2 genes by PCR amplification and scanning by conformation-sensitive gel electrophoresis identifies only COL1A1 mutations in 15 patients with osteogenesis imperfecta type I: identification of common sequences of null-allele mutations.

COL1A1 COL1A2

9.73e-06210929443882
Pubmed

Lack of correlation between the type of COL1A1 or COL1A2 mutation and hearing loss in osteogenesis imperfecta patients.

COL1A1 COL1A2

9.73e-062109215241796
Pubmed

Human Neutrophil Peptides 1-3--early markers in development of colorectal adenomas and carcinomas.

DEFA1 DEFA3

9.73e-062109218957723
Pubmed

Mutation spectrum of COL1A1 and COL1A2 genes in Indian patients with osteogenesis imperfecta.

COL1A1 COL1A2

9.73e-062109224668929
Pubmed

[Relationship of collagen type I alpha 1 and alpha 2 gene polymorphisms with bone mineral density].

COL1A1 COL1A2

9.73e-062109216864092
Pubmed

Evidence for a relationship between Ehlers-Danlos type VII C in humans and bovine dermatosparaxis.

COL1A1 COL1A2

9.73e-06210921303238
Pubmed

Regional chromosome mapping of human collagen genes alpha 2(I) and alpha 1(I) (COLIA2 and COLIA1).

COL1A1 COL1A2

9.73e-06210923857213
Pubmed

Substitutions for glycine alpha 1-637 and glycine alpha 2-694 of type I procollagen in lethal osteogenesis imperfecta. The conformational strain on the triple helix introduced by a glycine substitution can be transmitted along the helix.

COL1A1 COL1A2

9.73e-06210921874719
Pubmed

Differential unfolding of alpha1 and alpha2 chains in type I collagen and collagenolysis.

COL1A1 COL1A2

9.73e-062109218644377
Pubmed

COL1 C-propeptide cleavage site mutations cause high bone mass osteogenesis imperfecta.

COL1A1 COL1A2

9.73e-062109221344539
Pubmed

Hearing loss in individuals with osteogenesis imperfecta in North America: Results from a multicenter study.

COL1A1 COL1A2

9.73e-062109231876392
Pubmed

Helical mutations in type I collagen that affect the processing of the amino-propeptide result in an Osteogenesis Imperfecta/Ehlers-Danlos Syndrome overlap syndrome.

COL1A1 COL1A2

9.73e-062109223692737
Pubmed

Clinical features, molecular results, and management of 12 individuals with the rare arthrochalasia Ehlers-Danlos syndrome.

COL1A1 COL1A2

9.73e-062109232091183
Pubmed

Deletions and duplications of Gly-Xaa-Yaa triplet repeats in the triple helical domains of type I collagen chains disrupt helix formation and result in several types of osteogenesis imperfecta.

COL1A1 COL1A2

9.73e-062109211668615
Pubmed

Salivary levels of HNP 1-3 are related to oral ulcer activity in Behçet's disease.

DEFA1 DEFA3

9.73e-062109222861387
Pubmed

Gene expression patterns associated with infertility in humans and rodent models.

SPINK2 DLK1

9.73e-062109215120973
Pubmed

Predictive value of osteocalcin and beta-CrossLaps in metastatic breast cancer.

BGLAP COL1A1

9.73e-062109217889845
Pubmed

Influence of type I collagen polymorphisms and risk of anterior cruciate ligament rupture in athletes: a case-control study.

COL1A1 COL1A2

9.73e-062109235172811
Pubmed

Cranial base abnormalities in osteogenesis imperfecta: phenotypic and genotypic determinants.

COL1A1 COL1A2

9.73e-062109220721936
Pubmed

A cysteine-based molecular code informs collagen C-propeptide assembly.

COL1A1 COL1A2

9.73e-062109230310058
Pubmed

Use of the Cre/lox recombination system to develop a non-lethal knock-in murine model for osteogenesis imperfecta with an alpha1(I) G349C substitution. Variability in phenotype in BrtlIV mice.

COL1A1 COL1A2

9.73e-062109210608859
Pubmed

The significance of carboxy-terminal telopeptide of type I collagen (ICTP) and osteocalcin (OC) in assessment of bone disease in patients with multiple myeloma.

BGLAP COL1A1

9.73e-062109216263577
Pubmed

Defensins: antimicrobial and cytotoxic peptides of mammalian cells.

DEFA1 DEFA3

9.73e-06210928476558
Pubmed

Deposition of apatite in mineralizing vertebrate extracellular matrices: A model of possible nucleation sites on type I collagen.

COL1A1 COL1A2

9.73e-062109221405976
Pubmed

The human type I collagen mutation database.

COL1A1 COL1A2

9.73e-06210929016532
Pubmed

Mutations in type I collagen genes in Japanese osteogenesis imperfecta patients.

COL1A1 COL1A2

9.73e-062109217875077
Pubmed

Novel quantitative trait loci for central corneal thickness identified by candidate gene analysis of osteogenesis imperfecta genes.

COL1A1 COL1A2

9.73e-062109219714363
Pubmed

No association between polymorphisms and haplotypes of COL1A1 and COL1A2 genes and osteoporotic fracture in postmenopausal Chinese women.

COL1A1 COL1A2

9.73e-062109221602843
Pubmed

Age-related trends and reference intervals of cross-linked C-telopeptide of type I collagen and procollagen type I N-propeptide from a reference population of Sri Lankan adult women.

COL1A1 COL1A2

9.73e-062109234727246
Pubmed

Identification of COL1A1 and COL1A2 as candidate prognostic factors in gastric cancer.

COL1A1 COL1A2

9.73e-062109227894325
Pubmed

Scoliosis in osteogenesis imperfecta caused by COL1A1/COL1A2 mutations - genotype-phenotype correlations and effect of bisphosphonate treatment.

COL1A1 COL1A2

9.73e-062109226927310
Pubmed

Effects of GABA on the expression of type I collagen gene in normal human dermal fibroblasts.

COL1A1 COL1A2

9.73e-062109227691923
Pubmed

Identification of COL1A1/2 Mutations and Fusions With Noncoding RNA Genes in Bizarre Parosteal Osteochondromatous Proliferation (Nora Lesion).

COL1A1 COL1A2

9.73e-062109236853784
Pubmed

Inter- and Intrafamilial Phenotypic Variability in Individuals with Collagen-Related Osteogenesis Imperfecta.

COL1A1 COL1A2

9.73e-062109232166892
Pubmed

Comparing Clinical and Genetic Characteristics of De Novo and Inherited COL1A1/COL1A2 Variants in a Large Chinese Cohort of Osteogenesis Imperfecta.

COL1A1 COL1A2

9.73e-062109235909573
Pubmed

Mutation analysis of the COL1A1 and COL1A2 genes in Vietnamese patients with osteogenesis imperfecta.

COL1A1 COL1A2

9.73e-062109227519266
Pubmed

Localization of human neutrophil peptide (HNP) and its messenger RNA in neutrophil series.

DEFA1 DEFA3

9.73e-06210928080882
Pubmed

Mutation of the 5'-untranslated region stem-loop structure inhibits α1(I) collagen expression in vivo.

COL1A1 COL1A2

9.73e-062109221193410
Pubmed

COL1A1 and COL1A2 sequencing results in cohort of patients undergoing evaluation for potential child abuse.

COL1A1 COL1A2

9.73e-062109227090748
Pubmed

Assignment of the genes for mouse type I procollagen to chromosome 16 using mouse fibroblast-Chinese hamster somatic cell hybrids.

COL1A1 COL1A2

9.73e-06210926857446
Pubmed

Alpha-defensins secreted by dysplastic granulocytes inhibit the differentiation of monocytes in chronic myelomonocytic leukemia.

DEFA1 DEFA3

9.73e-062109219864642
Pubmed

Multidrug-resistant tuberculosis is associated with low plasma concentrations of human neutrophil peptides 1-3.

DEFA1 DEFA3

9.73e-062109221333105
Pubmed

Mutational spectrum of type I collagen genes in Korean patients with osteogenesis imperfecta.

COL1A1 COL1A2

9.73e-062109216705691
Pubmed

Four new cases of lethal osteogenesis imperfecta due to glycine substitutions in COL1A1 and genes. Mutations in brief no. 152. Online.

COL1A1 COL1A2

9.73e-062109210627137
Pubmed

Structural and mechanical differences between collagen homo- and heterotrimers: relevance for the molecular origin of brittle bone disease.

COL1A1 COL1A2

9.73e-062109222325288
Pubmed

Clinical characteristics and the identification of novel mutations of COL1A1 and COL1A2 in 61 Chinese patients with osteogenesis imperfecta.

COL1A1 COL1A2

9.73e-062109227748872
Pubmed

The type I collagen pro alpha 1(I) COOH-terminal propeptide N-linked oligosaccharide. Functional analysis by site-directed mutagenesis.

COL1A1 COL1A2

9.73e-06210927629088
Pubmed

Alpha-defensin overexpression in patients with Bell's palsy and Ramsay Hunt syndrome.

DEFA1 DEFA3

9.73e-062109222737966
Pubmed

Midpregnancy vaginal fluid defensins, bacterial vaginosis, and risk of preterm delivery.

DEFA1 DEFA3

9.73e-062109218757648
Pubmed

Severe (type III) osteogenesis imperfecta due to glycine substitutions in the central domain of the collagen triple helix.

COL1A1 COL1A2

9.73e-06210927881420
Pubmed

Simvastatin and atorvastatin enhance gene expression of collagen type 1 and osteocalcin in primary human osteoblasts and MG-63 cultures.

BGLAP COL1A1

9.73e-062109217252541
CytobandEnsembl 112 genes in cytogenetic band chr8p23

DEFB104A DEFA1 DEFA3 DEFA4 DEFB109B

2.50e-042341095chr8p23
Cytoband8p23.1

DEFB104A DEFA1 DEFA3 DEFB109B

5.15e-0415410948p23.1
GeneFamilySolute carriers

SLC38A4 SLC22A23 SLC26A5 SLC44A2 SLC10A3 SLC44A4 SLC7A14 SLC38A2 SLC2A6 SLC24A1

8.32e-063957910752
GeneFamilyDefensins, alpha

DEFA1 DEFA3 DEFA4

1.72e-0512793502
GeneFamilyTaste 2 receptors

TAS2R42 TAS2R40 TAS2R39

6.55e-04397931162
GeneFamilySerine peptidase inhibitors, Kazal type

SPINK2 SPINK9

8.29e-0410792740
GeneFamilyADAM metallopeptidase domain containing|CD molecules

CD52 SIRPA ITGA1 CLEC4M CD84 CD53 LY9

1.67e-03394797471
CoexpressionHE_LIM_SUN_FETAL_LUNG_C3_LYMPHATIC_ENDOTHELIAL_CELL

SUSD4 DOCK8 SLC22A23 SIRPA ITGA1 LAPTM5 EFNA5 IGFBP5 ACKR2 SLC24A1 EPHB1

4.00e-0738210511M45756
CoexpressionHE_LIM_SUN_FETAL_LUNG_C3_INTERMEDIATE_LYMPHATIC_ENDO_CELL

DOCK8 SLC38A4 SLC22A23 SIRPA CELSR1 RNASE4 EFNA5 IGFBP5 ACKR2 SLC24A1 EPHB1

6.61e-0740210511M45754
CoexpressionTRAVAGLINI_LUNG_LYMPHATIC_CELL

SIRPA LAPTM5 TGFBI SLC38A2 EFNA5 IGFBP5 ACKR2 SLC24A1

2.05e-062091058M41670
CoexpressionDESCARTES_ORGANOGENESIS_WHITE_BLOOD_CELLS

HFE CD52 DOCK8 DDX60 TMIGD3 SIRPA PKD1L2 LAPTM5 CD84 RNASE4 CD53 LY9

6.70e-0661510512MM3641
CoexpressionGSE16385_ROSIGLITAZONE_IL4_VS_IFNG_TNF_STIM_MACROPHAGE_DN

HFE GIMAP4 TMEM53 SPINK2 SLC38A4 EFNA5 TRPM3

1.49e-051971057M8025
CoexpressionSANSOM_APC_TARGETS_DN

GIMAP4 CD52 GBF1 DDR2 CXCL14 SIRPA LAPTM5 TGFBI CD53

1.69e-053661059M1432
CoexpressionLEE_AGING_NEOCORTEX_DN

HTR4 IFNA2 BGLAP ASIP LY9

1.77e-05801055MM646
CoexpressionMANNE_COVID19_COMBINED_COHORT_VS_HEALTHY_DONOR_PLATELETS_DN

ATP13A4 PF4V1 DLK1 TGFBI EFNA5 IGFBP5 ACKR2

3.39e-052241057M38981
CoexpressionRUBENSTEIN_SKELETAL_MUSCLE_NK_CELLS

GIMAP4 CD52 LAPTM5 SLC38A2 CUTA PRF1 CD53

3.59e-052261057M41749
CoexpressionKONDO_EZH2_TARGETS

SUSD4 TMEM116 RNASE4 IGFBP5 ACKR2 LY9 COL1A1

3.90e-052291057M5301
CoexpressionMANNE_COVID19_ICU_VS_HEALTHY_DONOR_PLATELETS_DN

PF4V1 DLK1 TGFBI EFNA5 IGFBP5 ACKR2

4.45e-051591056M38979
CoexpressionNABA_MATRISOME

ISM1 CXCL14 PF4V1 CLEC4M IFNA2 F12 BGLAP TGFBI OPTC THPO IGFBP5 SERPINA7 COL1A1 COL1A2

5.00e-05100810514MM17056
CoexpressionKIM_GLIS2_TARGETS_UP

CXCL14 PF4V1 TGFBI COL1A1 COL1A2

5.74e-051021055MM1064
CoexpressionNABA_MATRISOME

ISM1 CXCL14 PF4V1 CLEC4M IFNA2 F12 BGLAP TGFBI OPTC THPO IGFBP5 SERPINA7 COL1A1 COL1A2

6.05e-05102610514M5889
CoexpressionDESCARTES_FETAL_SPLEEN_AFP_ALB_POSITIVE_CELLS

SLC38A4 DLK1 F12 PRAP1 IGSF1 SERPINA7

1.12e-041881056M40287
CoexpressionWILCOX_RESPONSE_TO_PROGESTERONE_DN

IGFBP5 ATP2B4 COL1A1 COL1A2

1.13e-04621054M16774
CoexpressionCUI_DEVELOPING_HEART_COMPACT_VENTRICULAR_CARDIOMYOCYTE

CXCL14 DLK1 COL1A1 COL1A2

1.36e-04651054M39309
CoexpressionGSE3982_NKCELL_VS_TH1_UP

TP53I11 XKR8 SLC10A3 ZNF34 EFNA5 EPHB1

1.37e-041951056M5593
CoexpressionGSE23321_EFFECTOR_MEMORY_VS_NAIVE_CD8_TCELL_UP

SLC10A3 CD84 DEFA4 ASIP ATP2B4 GPRC5B

1.41e-041961056M8428
CoexpressionGSE24634_TREG_VS_TCONV_POST_DAY5_IL4_CONVERSION_DN

DDX60 SIRPA CD84 TGFBI SLC2A6 LY9

1.49e-041981056M4603
CoexpressionGSE25088_IL4_VS_IL4_AND_ROSIGLITAZONE_STIM_STAT6_KO_MACROPHAGE_DAY10_UP

GIMAP4 CD52 XKR8 PRCP TAS2R40 ATP2B4

1.49e-041981056M7944
CoexpressionGSE23502_BM_VS_COLON_TUMOR_HDC_KO_MYELOID_DERIVED_SUPPRESSOR_CELL_UP

TRHDE SLC38A4 VANGL2 ABCA6 CD53 FRMD5

1.53e-041991056M8082
CoexpressionGSE22025_TGFB1_VS_TGFB1_AND_PROGESTERONE_TREATED_CD4_TCELL_UP

TP53I11 SLC10A3 ITGA1 LAPTM5 CD84 LY9

1.53e-041991056M8380
CoexpressionGSE3337_CTRL_VS_4H_IFNG_IN_CD8POS_DC_UP

ABHD14A SLC22A23 SLC44A2 SIRPA HUWE1 TGFBI

1.57e-042001056M5097
CoexpressionPASTURAL_RIZ1_TARGETS_DN

DLK1 LAPTM5

1.58e-0451052M4364
CoexpressionLEE_AGING_NEOCORTEX_DN

HTR4 BGLAP ASIP LY9

1.63e-04681054M1497
CoexpressionMANNE_COVID19_NONICU_VS_HEALTHY_DONOR_PLATELETS_DN

ATP13A4 PF4V1 DLK1 TGFBI EFNA5 ACKR2

1.90e-042071056M38977
CoexpressionGARCIA_PINERES_PBMC_HPV_16_L1_VLP_AGE_18_25YO_STIMULATED_VS_UNSTIMULATED_0DY_VACCINATION_INDEPENDENT_DN

CELSR1 RNASE4 EFNA5 GPRC5B COL1A2

2.23e-041361055M41157
CoexpressionVERHAAK_GLIOBLASTOMA_MESENCHYMAL

HFE SLC10A3 LAPTM5 TGFBI COL1A1 COL1A2

2.39e-042161056M2122
CoexpressionAtlaskidney_adult_RenalCapsule_top-relative-expression-ranked_500

TTC39B CD52 DDX60 DDR2 ITGA1 LAPTM5 RNASE4 EFNA5 IGFBP5 CD53 COL1A1 COL1A2

5.50e-0740810112gudmap_kidney_adult_RenalCapsule_500
CoexpressionAtlasBM Top 100 - ovary

DLK1 RNASE4 IGFBP5 GREB1 COL1A1 COL1A2

1.02e-06701016BM Top 100 - ovary
CoexpressionAtlasliver

CYP2B6 SLC38A4 CLEC4M F12 RNASE4 THPO ABCA6 PRAP1 SERPINA7 CNDP1

3.12e-0541910110liver
CoexpressionAtlaskidney_adult_Mesangium_Meis_k-means-cluster#4_top-relative-expression-ranked_500

DDX60 DDR2 ITGA1 IGFBP5

3.86e-05401014gudmap_kidney_adult_Mesangium_Meis_k4_500
CoexpressionAtlasStromal Cells, Fi.Sk, gp38+ CD140a+, Skin, avg-4

DDR2 ISM1 CXCL14 DLK1 TGFBI RNASE4 IGFBP5 ABCA6 COL1A1 COL1A2

4.45e-0543710110GSM777046_500
CoexpressionAtlasProgenitor-Cell-Biology-Consortium_induced-Ectoderm_fromBlastocyst-derived-humanEmbryonicStemCells_top-relative-expression-ranked_1000

ATP13A4 CD52 DOCK8 SLC38A4 DEFB104A CXCL14 RNF183 DLK1 PKD1L2 TRPM3 PROM2 TRPV6 GREB1 IGSF1 SHISA6

5.70e-0597610115PCBC_ECTO_blastocyst_1000
CoexpressionAtlaskidney_adult_RenalCapsule_top-relative-expression-ranked_1000

TTC39B CD52 DDX60 DDR2 SLC44A2 ITGA1 LAPTM5 RNASE4 EFNA5 IGFBP5 CD53 COL1A1 COL1A2

8.10e-0577810113gudmap_kidney_adult_RenalCapsule_1000
CoexpressionAtlasProgenitor-Cell-Biology-Consortium_induced-Ectoderm_fromBlastocyst-derived-humanEmbryonicStemCells_top-relative-expression-ranked_500

ATP13A4 DOCK8 SLC38A4 DEFB104A CXCL14 RNF183 PKD1L2 TRPM3 TRPV6 SHISA6

1.09e-0448710110PCBC_ECTO_blastocyst_500
CoexpressionAtlasPP_HSC_top-relative-expression-ranked_100

CD52 SPINK2 LAPTM5 CD84 CD53

1.16e-041001015PP_HSC_100
CoexpressionAtlasDevelopingKidney_e11.5_ureteric bud_emap-3844_top-relative-expression-ranked_1000

SUSD4 DOCK8 SLC38A4 PM20D1 CXCL14 VANGL2 CELSR1 PROM2 TRPV6 GREB1 FRMD5 GPRC5B CNDP1

1.26e-0481310113gudmap_developingKidney_e11.5_ureteric bud_1000
CoexpressionAtlaskidney_adult_RenalCapsule_k-means-cluster#1_top-relative-expression-ranked_500

CD52 DDR2 LAPTM5 RNASE4 EFNA5 COL1A1 COL1A2

1.51e-042401017gudmap_kidney_adult_RenalCapsule_k1_500
CoexpressionAtlasDevelopingLowerUrinaryTract_P2_bladder urothelium (LCM)_emap-30380_k-means-cluster#1_top-relative-expression-ranked_500

HTR4 DOCK8 PM20D1 CXCL14

1.57e-04571014gudmap_developingLowerUrinaryTract_P2_bladder urothelium (LCM)_500_k1
CoexpressionAtlasDevelopingLowerUrinaryTract_P2_bladder urothelium (LCM)_emap-30380_k-means-cluster#1_top-relative-expression-ranked_200

HTR4 PM20D1 PROM2

1.73e-04231013gudmap_developingLowerUrinaryTract_P2_bladder urothelium (LCM)_200_k1
CoexpressionAtlasalpha beta T cells, NKT.4-.Sp, TCRbeta+ aGalCer tet+ CD4-, Spleen, avg-3

GIMAP4 TTC39B DDX60 ITGA1 CD84 PRF1 LY9 ATP2B4

1.84e-043311018GSM538329_500
CoexpressionAtlasratio_EmbryoidBody_vs_StemCell_top-relative-expression-ranked_1000_k-means-cluster#1

DDR2 GPR85 ITGA1 TGFBI RNASE4 IGFBP5 COL1A1 COL1A2

2.04e-043361018ratio_EB_vs_SC_1000_K1
CoexpressionAtlasMesoderm Day 15-reprogram_NA_vs_Mesoderm Day 15-reprogram_OSK-L-l-p53KD-Confounder_removed-fold2.0_adjp0.05

ITGA1 SLC44A4 PRAP1 IGSF1 GNRH2 SERPINA7

2.16e-041791016PCBC_ratio_MESO-15_from-ESC_vs_MESO-15_from-OSK-L-l-p53KD_cfr-2X-p05
CoexpressionAtlasMesoderm Day 15-method_NA_vs_Mesoderm Day 15-method_episomal-Confounder_removed-fold2.0_adjp0.05

ITGA1 SLC44A4 PRAP1 IGSF1 GNRH2 SERPINA7

2.16e-041791016PCBC_ratio_MESO-15_from-ESC_vs_MESO-15_from-episomal_cfr-2X-p05
CoexpressionAtlasFacebaseRNAseq_e10.5_Olfactory Pit_top-relative-expression-ranked_1000

TTC39B CD52 SUSD4 SLC22A23 SLC26A5 TP53I11 DLK1 CELSR1 RNASE4 PROM2 ATP2B4 FRMD5 COL1A1 COL1A2

2.30e-0498410114Facebase_RNAseq_e10.5_Olfactory Pit_1000
CoexpressionAtlasratio_EmbryoidBody_vs_StemCell_top-relative-expression-ranked_500_k-means-cluster#5

DDR2 TGFBI IGFBP5 COL1A1 COL1A2

2.33e-041161015ratio_EB_vs_SC_500_K5
CoexpressionAtlasDevelopingGonad_P2_testes_emap-30171_k-means-cluster#2_top-relative-expression-ranked_100

GPR37 DLK1 COL1A1

2.51e-04261013gudmap_developingGonad_P2_testes_100_k2
CoexpressionAtlasalpha beta T cells, NKT.4+.Lv, CD45 TCRb aGalCer-loaded CD1d tet CD4, Liver, avg-4

GIMAP4 TTC39B DDX60 ITGA1 CD84 PRF1 LY9 ATP2B4

2.68e-043501018GSM538318_500
CoexpressionAtlasFacebaseRNAseq_e10.5_Maxillary Arch_top-relative-expression-ranked_2500_k-means-cluster#4

GIMAP4 CD52 DDR2 SLC26A5 ITGA1 BGLAP LAPTM5 RNASE4 ATP2B4 COL1A1 COL1A2

2.84e-0465510111Facebase_RNAseq_e10.5_Maxillary Arch_2500_K4
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ bladder_emap-30872_k-means-cluster#1_top-relative-expression-ranked_1000

GPR37 SLC38A4 PRCP COL1A1 EPHB1

3.17e-041241015gudmap_developingLowerUrinaryTract_e14.5_ bladder_1000_k1
CoexpressionAtlasJC_fibro_top-relative-expression-ranked_1000_k-means-cluster#1

TRHDE HFE DDX60 DDR2 ITGA1 TGFBI IGFBP5 COL1A1 COL1A2

3.71e-044641019JC_fibro_1000_K1
CoexpressionAtlasDevelopingGonad_e12.5_testes_emap-29069_k-means-cluster#2_top-relative-expression-ranked_200

GPR37 DLK1 COL1A1

3.86e-04301013gudmap_developingGonad_e12.5_testes_k2_200
CoexpressionAtlasFacebaseRNAseq_e9.5_Maxillary Arch_top-relative-expression-ranked_1000_k-means-cluster#1

TRHDE CD52 ITGA1 BGLAP RNASE4 ATP2B4 COL1A1 COL1A2

3.96e-043711018Facebase_RNAseq_e9.5_Maxillary Arch_1000_K1
CoexpressionAtlasDevelopingLowerUrinaryTract_e13.5_bladder neck-urethr epithel_emap-30875_top-relative-expression-ranked_1000

SUSD4 HTR4 GPR85 PM20D1 CXCL14 HUWE1 CELSR1 IGFBP5 PROM2 GRAMD1C FRMD5 GPRC5B

4.15e-0480010112gudmap_developingLowerUrinaryTract_e13.5_bladder neck-urethr epithel_1000
CoexpressionAtlasMesoderm Day 15_vs_Mesoderm Day 5-Confounder_removed-fold2.0_adjp0.05

GBF1 SLC22A23 CXCL14 DLK1 SIRPA SLC44A4 TGFBI RNASE4 PRAP1 IGSF1 GNRH2 SERPINA7 COL1A1 COL1A2

4.39e-04104910114PCBC_ratio_MESO-15_vs_MESO-5_cfr-2X-p05
CoexpressionAtlasDevelopingKidney_e15.5_Peripheral blastema_emap-27731_k-means-cluster#2_top-relative-expression-ranked_500

TTC39B SLC38A4 DDR2 GPR85 XKR8 IGFBP5

4.57e-042061016gudmap_developingKidney_e15.5_Peripheral blastema_500_k2
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-5517_k-means-cluster#3_top-relative-expression-ranked_1000

GPR85 SLC7A14 LAPTM5 IGFBP5 NALCN GPRC5B

4.69e-042071016gudmap_developingLowerUrinaryTract_e14.5_ urogenital sinus_1000_k3
CoexpressionAtlasDevelopingKidney_e12.5_renal vesicle_emap-27679_top-relative-expression-ranked_100

ISM1 CXCL14 CELSR1 GREB1

4.76e-04761014gudmap_developingKidney_e12.5_renal vesicle_100
CoexpressionAtlasFacebaseRNAseq_e9.5_Facial Mesenchyne_top-relative-expression-ranked_1000_k-means-cluster#3

TRHDE SLC26A5 ITGA1 BGLAP RNASE4 ATP2B4 COL1A1 COL1A2

4.98e-043841018Facebase_RNAseq_e9.5_Facial Mesenchyne_1000_K3
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ urethra_emap-30892_k-means-cluster#2_top-relative-expression-ranked_500

TRHDE GPR85 CXCL14 HUWE1 GPRC5B

5.01e-041371015gudmap_developingLowerUrinaryTract_e14.5_ urethra_500_k2
CoexpressionAtlasDevelopingKidney_e15.5_Podocyte cells_emap-27915_k-means-cluster#2_top-relative-expression-ranked_500

HFE GIMAP4 LAPTM5 CD53 EPHB1

5.35e-041391015gudmap_developingKidney_e15.5_Podocyte cells_500_k2
CoexpressionAtlasAravindRamakr_EmbryoidBody-LF_top-relative-expression-ranked_2500_k-means-cluster#2

TRHDE DDR2 ISM1 CXCL14 DLK1 ITGA1 TGFBI CDH20 IGFBP5 TRPM3 GNRH2 COL1A1 COL1A2

5.70e-0495110113Arv_EB-LF_2500_K2
CoexpressionAtlasFacebaseRNAseq_e10.5_Olfactory Pit_top-relative-expression-ranked_500

TTC39B SUSD4 SLC22A23 SLC26A5 TP53I11 DLK1 CELSR1 PROM2 FRMD5

5.92e-044951019Facebase_RNAseq_e10.5_Olfactory Pit_500
CoexpressionAtlasDevelopingLowerUrinaryTract_e13.5_bladder neck-urethr epithel_emap-30875_k-means-cluster#2_top-relative-expression-ranked_200

HTR4 PM20D1 PROM2

6.12e-04351013gudmap_developingLowerUrinaryTract_e13.5_bladder neck-urethr epithel_200_k2
CoexpressionAtlasDevelopingKidney_e15.5_Podocyte cells_emap-27915_k-means-cluster#1_top-relative-expression-ranked_1000

HFE GIMAP4 SIRPA LAPTM5 CD53 EPHB1

6.31e-042191016gudmap_developingKidney_e15.5_Podocyte cells_1000_k1
CoexpressionAtlasDevelopingKidney_e11.5_ureteric bud_emap-3844_k-means-cluster#5_top-relative-expression-ranked_1000

SUSD4 DOCK8 SLC38A4 PROM2 TRPV6 FRMD5 GPRC5B

6.52e-043061017gudmap_developingKidney_e11.5_ureteric bud_1000_k5
CoexpressionAtlasFacebaseRNAseq_e9.5_Facial Mesenchyne_top-relative-expression-ranked_1000

TRHDE TTC39B CD52 SLC26A5 DLK1 ITGA1 BGLAP RNASE4 PRAP1 GREB1 ATP2B4 COL1A1 COL1A2

6.72e-0496810113Facebase_RNAseq_e9.5_Facial Mesenchyne_1000
CoexpressionAtlasStromal Cells, St.31-38-44-.SLN, CD45- gp38- CD31- CD44-, Lymph Node, avg-2

ITGA1 IGFBP5 COL1A1 COL1A2

7.27e-04851014GSM777067_100
CoexpressionAtlasStromal Cells, FRC.SLN, gp38+ CD31- CD140a+, Lymph Node, avg-4

TGFBI IGFBP5 COL1A1 COL1A2

7.59e-04861014GSM777055_100
CoexpressionAtlasAravindRamakr_EmbryoidBody-LF_top-relative-expression-ranked_1000

TRHDE ISM1 CXCL14 DLK1 DEFA1 TGFBI DEFA4 CDH20 TRPM3 GNRH2 SHISA6 COL1A1 COL1A2

7.61e-0498110113Arv_EB-LF_1000
CoexpressionAtlasProgenitor-Cell-Biology-Consortium_reference_PulmonMicrovasc_top-relative-expression-ranked_1000

GIMAP4 SLC38A4 SLC22A23 SIRPA ITGA1 CLEC4M LAPTM5 NALCN ABCA6 DDX60L SLC24A1 GRAMD1C GPRC5B

7.61e-0498110113PCBC_ctl_PulmonMicrovasc_1000
CoexpressionAtlasFacebaseRNAseq_e10.5_Neural Epithelium Overlying Central Eminence_top-relative-expression-ranked_1000_k-means-cluster#2

TTC39B TP53I11 DLK1 CELSR1

7.93e-04871014Facebase_RNAseq_e10.5_Neural Epithelium Overlying Central Eminence_1000_K2
CoexpressionAtlasProgenitor-Cell-Biology-Consortium_induced-Ectoderm_from_inducedPluripotentialStemCells_derived from_from_fibroblast_top-relative-expression-ranked_1000

ATP13A4 CD52 DOCK8 SLC38A4 DEFB104A CXCL14 DLK1 PKD1L2 CDH20 TRPM3 TRPV6 GREB1 IGSF1

8.35e-0499110113PCBC_ECTO_fibroblast_1000
CoexpressionAtlasratio_EmbryoidBody_vs_StemCell_top-relative-expression-ranked_1000

DDR2 GPR85 ISM1 CXCL14 DLK1 ITGA1 TGFBI RNASE4 CDH20 IGFBP5 GNRH2 COL1A1 COL1A2

8.59e-0499410113PCBC_ratio_EB_vs_SC_1000
CoexpressionAtlasMesoderm Day 30-reprogram_OSK-L-l-p53KD_vs_Mesoderm Day 30-reprogram_NA-Confounder_removed-fold2.0_adjp0.05

GPR37 CXCL14 IGFBP5 SERPINA7

8.64e-04891014PCBC_ratio_MESO-30_from-OSK-L-l-p53KD_vs_MESO-30_from-ESC_cfr-2X-p05
CoexpressionAtlasMesoderm Day 30-method_episomal_vs_Mesoderm Day 30-method_NA-Confounder_removed-fold2.0_adjp0.05

GPR37 CXCL14 IGFBP5 SERPINA7

8.64e-04891014PCBC_ratio_MESO-30_from-episomal_vs_MESO-30_from-ESC_cfr-2X-p05
CoexpressionAtlasDevelopingKidney_e15.5_Peripheral blastema_emap-27731_top-relative-expression-ranked_500

TTC39B SLC38A4 DDR2 GPR85 XKR8 HUWE1 TGFBI IGFBP5

9.06e-044211018gudmap_developingKidney_e15.5_Peripheral blastema_500
CoexpressionAtlasDevelopingGonad_P2_epididymis_emap-30199_top-relative-expression-ranked_200

SPINK9 DLK1 NALCN COL1A1 CNDP1

9.28e-041571015gudmap_developingGonad_P2_epididymis_200
CoexpressionAtlasMyeloid Cells, DC.II+480lo.PC, F4/80lo MHC II+ CD11c+ CD115+, Peritoneal Cavity, avg-3

HFE SPINK2 SIRPA CD84 TGFBI ABCA6 PRCP SLC2A6

9.48e-044241018GSM854294_500
CoexpressionAtlasMyeloid Cells, MF.Thio5.II+480lo.PC, CD115+ MHC II+ F480lo SiglecF- CD11c+, Peritoneal Cavity, avg-3

HFE SPINK2 SIRPA CLEC4M TGFBI ABCA6 PRCP SLC2A6

9.77e-044261018GSM605859_500
CoexpressionAtlasDevelopingKidney_e15.5_S-shaped body_emap-27855_k-means-cluster#3_top-relative-expression-ranked_200

GIMAP4 EPHB1

9.83e-04101012gudmap_developingKidney_e15.5_S-shaped body_200_k3
CoexpressionAtlasDevelopingKidney_e12.5_renal vesicle_emap-27679_top-relative-expression-ranked_200

ISM1 CXCL14 CELSR1 GREB1 EPHB1

1.04e-031611015gudmap_developingKidney_e12.5_renal vesicle_200
CoexpressionAtlasDevelopingKidney_e15.5_S-shaped body_emap-27855_k-means-cluster#4_top-relative-expression-ranked_200

CXCL14 CELSR1 GREB1

1.05e-03421013gudmap_developingKidney_e15.5_S-shaped body_200_k4
CoexpressionAtlasDevelopingKidney_e15.5_S-shaped body_emap-27855_top-relative-expression-ranked_200

GIMAP4 CXCL14 CELSR1 GREB1 EPHB1

1.07e-031621015gudmap_developingKidney_e15.5_S-shaped body_200
CoexpressionAtlasgeo_heart_top-relative-expression-ranked_1000_k-means-cluster#1

DPY19L2 LAPTM5 PRF1 CD53

1.10e-03951014geo_heart_1000_K1
CoexpressionAtlasDevelopingLowerUrinaryTract_P1_bladder_J_emap-30374_top-relative-expression-ranked_1000

HTR4 DOCK8 SLC22A23 DDR2 PM20D1 CXCL14 ITGA1 OPTC PROM2 GPRC5B COL1A1

1.11e-0377210111gudmap_developingLowerUrinaryTract_P1_bladder_1000_J
CoexpressionAtlasdev gonad_e11.5_M_GonadVasMes_Flk_k-means-cluster#1_top-relative-expression-ranked_1000

SLC38A4 DLK1 TGFBI EFNA5 IGFBP5 ATP2B4 COL1A2

1.15e-033371017gudmap_dev gonad_e11.5_M_GonadVasMes_Flk_k1_1000
ToppCellfacs-Brain_Non-Myeloid-Cortex-24m-Lymphocytic-mature_NK_T_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GIMAP4 CD52 DOCK8 LAPTM5 CD84 PRF1 CD53 LY9 SLC24A1

2.16e-10159109932d4c9f7ba6a96ce8443396b80568b41cbfc4927
ToppCellLPS-IL1RA+antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-MatrixFB_->_Myofibroblast|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

HTR4 DDR2 ISM1 TGFBI EFNA5 IGFBP5 NALCN FRMD5 COL1A2

8.27e-1018510993b2dfc8f4c87be516265dbecfc251276034d0efd
ToppCellcontrol-Lymphoid-CTL|control / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

GIMAP4 CD52 DOCK8 ITGA1 LAPTM5 CD84 PRF1 CD53 LY9

1.10e-0919110998df23473e24cfa51c09986102ddd391ed0f0b9cc
ToppCellcontrol-Lymphoid|control / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

GIMAP4 CD52 DOCK8 ITGA1 LAPTM5 CD84 PRF1 CD53 LY9

1.38e-0919610998ed172bb3a95f09722476f0880ae246561777d98
ToppCellNS-control-d_0-4-Lymphoid|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

GIMAP4 CD52 DOCK8 ITGA1 LAPTM5 CD84 PRF1 CD53 LY9

1.44e-091971099bd3f2d68eb108fe31e217c9124183920e7c82582
ToppCellLPS_only-Mesenchymal_myocytic-Myofibroblastic|LPS_only / Treatment groups by lineage, cell group, cell type

HTR4 DDR2 ISM1 ITGA1 TGFBI IGFBP5 NALCN COL1A1 COL1A2

1.64e-09200109902cae2c296a13ad4cbb53bca7a86d64629d67d66
ToppCellfacs-Brain_Non-Myeloid-Striatum_-18m-Lymphocytic|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GIMAP4 TTC39B CD52 LAPTM5 CD84 PRF1 CD53 LY9

4.92e-09156109839aa3adbee9f04cdc0055487d393edfa515e062b
ToppCellfacs-Brain_Non-Myeloid-Striatum_-18m-Lymphocytic-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GIMAP4 TTC39B CD52 LAPTM5 CD84 PRF1 CD53 LY9

4.92e-091561098a09e3aefe78d63ad5428ad48c6f83e547eb819f6
ToppCellP28-Endothelial-lymphatic_endothelial_cell|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

SUSD4 TP53I11 SIRPA CELSR1 RNASE4 EFNA5 ATP2B4 GPRC5B

1.33e-0817710986e330aa3c87fd640526b746a9deb3b2250d2518c
ToppCellP28-Endothelial-lymphatic_endothelial_cell-endothelial_cell_of_lymphatic_vessel|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

SUSD4 TP53I11 SIRPA CELSR1 RNASE4 EFNA5 ATP2B4 GPRC5B

1.33e-081771098e96a7e4544710aaab8bd2800ecff9667880a8bf4
ToppCellLPS-IL1RA-Stromal_mesenchymal-Lung_smooth_muscle-MatrixFB_->_Myofibroblast|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

HTR4 ISM1 TGFBI EFNA5 IGFBP5 NALCN COL1A1 COL1A2

1.45e-08179109802c90d8306016365ed811f0c63cfb3ac7b85464c
ToppCell5'-Adult-SmallIntestine-Mesenchymal-fibroblastic-Stromal_1_(ADAMDEC1+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

DDR2 CXCL14 PF4V1 TGFBI ABCA6 GREB1 COL1A1 COL1A2

1.51e-081801098f2f6e83127a4a415e65c76a35efa8175fbd5b5d9
ToppCell5'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-myocytic_fibroblast|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

HTR4 ITGA1 RNASE4 IGFBP5 NALCN ABCA6 COL1A1 COL1A2

1.58e-0818110989c157de9d3403e092c907599f2a2c16db5b21131
ToppCell3'-GW_trimst-1-SmallIntestine-Hematopoietic-B_cells-CLP|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CD52 SPINK2 DOCK8 LAPTM5 CD84 PRF1 CD53 LY9

1.58e-0818110981110a0375189c034e6b02e6ebceb7084e4590114
ToppCell5'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-myocytic_fibroblast-Myofibroblasts|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

HTR4 ITGA1 RNASE4 IGFBP5 NALCN ABCA6 COL1A1 COL1A2

1.58e-081811098eea943fdcbef0bbaa8578f3296923e874893b405
ToppCell5'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-myocytic_fibroblast-Myofibroblasts-Myofibroblasts_L.2.3.2.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

HTR4 ITGA1 RNASE4 IGFBP5 NALCN ABCA6 COL1A1 COL1A2

1.72e-081831098bc7dd6a40ec9c773d005c1a46f305d40cdd0a326
ToppCellLPS_only-Stromal_mesenchymal-Lung_smooth_muscle-MatrixFB_->_Myofibroblast|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

HTR4 DDR2 ISM1 ITGA1 TGFBI NALCN COL1A1 COL1A2

1.72e-08183109812daaea821e49bc94a01e2496331e92a80d27339
ToppCellLPS-antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-MatrixFB_->_Myofibroblast|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

HTR4 DDR2 ISM1 TGFBI EFNA5 IGFBP5 NALCN COL1A2

1.87e-0818510986712512100ccef456d2e2bd201d0987986c92ac9
ToppCellEndoth-Lymph|World / shred by cell class for parenchyma

GIMAP4 SLC38A4 SIRPA LAPTM5 EFNA5 ACKR2 SLC24A1 GPRC5B

1.87e-08185109897a6c4cd00684d4085d36ef32f7dbb99563ed357
ToppCell5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-Adventitial_fibroblasts_L.2.1.2.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DDR2 CXCL14 RNASE4 IGFBP5 ABCA6 GREB1 COL1A1 COL1A2

2.12e-081881098e18065bbc26d6f3774fd1f478fb41d8fb555fa26
ToppCelldroplet-Lung-18m-Endothelial-lymphatic_endothelial-lymphatic_endothelial_cell|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SUSD4 CELSR1 EFNA5 IGFBP5 TRPV6 ATP2B4 GPRC5B EPHB1

2.30e-081901098e80d66ba0d5c263e94c1ab0b89d1dc7b837af3e1
ToppCelldroplet-Lung-18m-Endothelial-lymphatic_endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SUSD4 CELSR1 EFNA5 IGFBP5 TRPV6 ATP2B4 GPRC5B EPHB1

2.30e-081901098f32d66c0e74e0a2a23ecb857c4daf0d8573a806c
ToppCelldroplet-Lung-18m-Endothelial-lymphatic_endothelial|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SUSD4 CELSR1 EFNA5 IGFBP5 TRPV6 ATP2B4 GPRC5B EPHB1

2.30e-081901098b79ffd05806244a9790cd04c66fb4f92c824e69f
ToppCellNS-control-d_0-4-Lymphoid-CTL|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

GIMAP4 CD52 ITGA1 LAPTM5 CD84 PRF1 CD53 LY9

2.40e-08191109827f2151da2f41015a979499f274ab1284a36189f
ToppCellEndothelial_cells-Endothelial-B|Endothelial_cells / lung cells shred on cell class, cell subclass, sample id

SLC22A23 SIRPA LAPTM5 EFNA5 IGFBP5 ACKR2 SLC24A1 GPRC5B

2.93e-08196109836f95f9ef74eb951e41ef46fd136ceaef45208fc
ToppCelltumor_Lung-Endothelial_cells-Lymphatic_ECs|Endothelial_cells / Location, Cell class and cell subclass

SLC22A23 SIRPA LAPTM5 SLC38A2 EFNA5 ACKR2 SLC24A1 EPHB1

3.05e-081971098a05237ee6d31d9eab491dd7007859d6285cf1424
ToppCellParenchyma_Control_(B.)-Stromal-TX-Mesothelial-2|Parenchyma_Control_(B.) / Sample group, Lineage and Cell type

DDR2 CXCL14 PF4V1 DEFA3 DEFA4 IGFBP5 COL1A1 COL1A2

3.43e-082001098b33901d91b3af5c0cf310eede30ce03af90c9783
ToppCellLPS_IL1RA_TNF-Mesenchymal_myocytic-Myofibroblastic-MatrixFB_->_Myofibroblast|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

HTR4 GPR37 DDR2 ITGA1 TGFBI IGFBP5 NALCN COL1A2

3.43e-08200109809537dc25f8b8b4654a7c183827ee1522a41a4e0
ToppCellLung_Parenchyma-Control-Mesenchymal-Mesenchymal-Mesothelial-2|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

DDR2 CXCL14 PF4V1 DEFA3 DEFA4 IGFBP5 COL1A1 COL1A2

3.43e-08200109823bc13983f6bdf95e63109b8bc14c4921ca85c3a
ToppCellLung_Parenchyma-Control-Mesenchymal-Mesenchymal-Mesothelial-2-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

DDR2 CXCL14 PF4V1 DEFA3 DEFA4 IGFBP5 COL1A1 COL1A2

3.43e-082001098d276062545ecc428a28b12a74f06f3c6bbcff4a3
ToppCellE16.5-Immune-Immune_Myeloid-Monocytic-Macrophage-IM-IM_prolif|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CD52 DDX60 SIRPA LAPTM5 CD84 RNASE4 CD53

1.39e-07160109718954241e11309ecb0f3ca87897eadcb20dc8eca
ToppCellfacs-SCAT-Fat-3m-Myeloid-myeloid_cell|SCAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CD52 DOCK8 LAPTM5 CD84 TGFBI PRCP CD53

1.78e-0716610978395c74db8e4e54af97a3f2b75cb75171140ec31
ToppCellfacs-SCAT-Fat-3m-Myeloid|SCAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CD52 DOCK8 LAPTM5 CD84 TGFBI PRCP CD53

1.78e-07166109776807edc5620514b53a14be354b84c54c112b8f9
ToppCellfacs-SCAT-Fat-3m-Myeloid-nan|SCAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CD52 DOCK8 LAPTM5 CD84 TGFBI PRCP CD53

1.78e-071661097645b842b94b8d2f4b26c2623f8589f56bd782c26
ToppCelldroplet-Heart-nan-18m-Hematologic-leukocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CD52 DOCK8 SIRPA LAPTM5 CD84 TGFBI CD53

2.09e-0717010977077eaf68ac859f63d6581d26a95c20d6a04bd28
ToppCellfacs-GAT-Fat-3m-Myeloid-nan|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CD52 DOCK8 LAPTM5 CD84 TGFBI PRCP CD53

2.18e-0717110973f796d53d3110e5d6e97de53bb49d323944659d6
ToppCellfacs-GAT-Fat-3m-Myeloid-myeloid_cell|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CD52 DOCK8 LAPTM5 CD84 TGFBI PRCP CD53

2.18e-071711097d9fbc2b00dbf9dddc95d9a20d804459a9ebd1820
ToppCellfacs-GAT-Fat-3m-Myeloid|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CD52 DOCK8 LAPTM5 CD84 TGFBI PRCP CD53

2.18e-071711097e77bfc925d73ccffe3c8cfb13764e70579a7f942
ToppCellfacs-Lung-18m-Hematologic-myeloid|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CD52 DOCK8 SIRPA LAPTM5 TGFBI SLC2A6 CD53

2.18e-0717110974ad28ecfde3d529a09b80be908c446bd5274518e
ToppCellPND07-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_T-CD8_T-CD8_T_mature|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

TRHDE GIMAP4 CD52 LAPTM5 PRF1 CD53 LY9

2.18e-071711097801893c318f7b1abc8d97bac86a00974f910a71c
ToppCellfacs-Lung-nan-3m-Lymphocytic|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRHDE GIMAP4 CD52 LAPTM5 CD84 PRF1 CD53

2.27e-0717210977af0713c40ea48f1e92c859c4fc4d8f0137c4415
ToppCellfacs-Lung-ENDOMUCIN-18m-Myeloid|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CD52 SIRPA LAPTM5 CD84 TGFBI SLC2A6 CD53

2.27e-0717210970457ccc18697aaec44b7c30ae157aae8f48d8785
ToppCellE16.5-Immune-Immune_Myeloid-Monocytic-Macrophage-IM|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CD52 DDX60 SIRPA LAPTM5 CD84 RNASE4 CD53

2.27e-071721097714172f31abd0d25261df6115ec6a9df491fa14b
ToppCellfacs-Lung-EPCAM-18m-Lymphocytic-CD8+_T|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GIMAP4 CD52 LAPTM5 CD84 PRF1 CD53 LY9

2.45e-071741097986e591d3d46009e53548dfa1f2126cf31063ef4
ToppCellfacs-Lung-EPCAM-18m-Lymphocytic-CD8-positive,_alpha-beta_T_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GIMAP4 CD52 LAPTM5 CD84 PRF1 CD53 LY9

2.45e-071741097785be49a2dbbb1dff0fbced1b48b942c2f4a508d
ToppCellfacs-Lung-18m-Hematologic-lymphocytic-CD8-positive,_alpha-beta_T_cell|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

GIMAP4 CD52 LAPTM5 CELSR1 PRF1 CD53 LY9

2.45e-0717410977c8cc5c2872fc7bcca7ebddaf5a6f20e617a2674
ToppCell3'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-myocytic_fibroblast-Myofibroblasts-Myofibroblasts_L.2.3.2.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ISM1 ITGA1 SLC38A2 IGFBP5 NALCN COL1A1 COL1A2

2.55e-0717510971799a7be623dc3bf53ba580a7c47d2619969d708
ToppCell3'-GW_trimst-1-SmallIntestine-Hematopoietic-Myeloid-pDC|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CD52 DOCK8 LAPTM5 ASIP CD53 LY9 EPHB1

2.86e-071781097b7d1d8f76c1c2467b1a39a9b4150ed4a47144a15
ToppCellT_cells-GZMK+_CD8+_T_cells|T_cells / Immune cells in Kidney/Urine in Lupus Nephritis

GIMAP4 TTC39B TP53I11 ITGA1 CD84 SLC2A6 LY9

2.97e-071791097798f208014f2229c597934775646ddbbacf94b69
ToppCellPND28-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial-Mesothelial_mature|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SPINK2 RNASE4 EFNA5 IGFBP5 COL1A1 COL1A2 EPHB1

3.20e-071811097330d4322f4c4373f706273c1f4e218b59051b7fd
ToppCellFetal_29-31_weeks-Mesenchymal-myofibroblast_cell-D062|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

DDR2 ISM1 CXCL14 ITGA1 TGFBI IGFBP5 NALCN

3.20e-071811097d7e04e0ca549eac6d9b1192b6578f9b54943d54f
ToppCellPND28-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SPINK2 RNASE4 EFNA5 IGFBP5 COL1A1 COL1A2 EPHB1

3.20e-0718110973f4d5d79c1286614514b0e8134079d6128a2a23e
ToppCellfacs-Lung-24m-Endothelial-lymphatic_endothelial-lymphatic_endothelial_cell|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SUSD4 CELSR1 RNASE4 EFNA5 ATP2B4 GPRC5B EPHB1

3.32e-0718210972cc434e46985c66fc36de05344a67aa96d90abc9
ToppCellfacs-Lung-24m-Endothelial-lymphatic_endothelial|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SUSD4 CELSR1 RNASE4 EFNA5 ATP2B4 GPRC5B EPHB1

3.32e-0718210970cde2775bdaaa2172499925bd59b0ac2d545eb27
ToppCellfacs-Lung-24m-Endothelial-lymphatic_endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SUSD4 CELSR1 RNASE4 EFNA5 ATP2B4 GPRC5B EPHB1

3.32e-0718210973e7457b2a70b45735fb75d6617b7f34cef28758e
ToppCelldroplet-Limb_Muscle-MUSCLE-30m-Lymphocytic-nan|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GIMAP4 CD52 DOCK8 LAPTM5 CD84 CD53 LY9

3.58e-0718410978fa7aa2a954f66576ada56670b4e1bb122864761
ToppCelldroplet-Limb_Muscle-MUSCLE-30m-Lymphocytic|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GIMAP4 CD52 DOCK8 LAPTM5 CD84 CD53 LY9

3.58e-071841097b5fbfcf8516c2dc20dffc36803692505a63f1297
ToppCellAdult-Mesenchymal-matrix_fibroblast_2_cell-D231|Adult / Lineage, Cell type, age group and donor

DDR2 ISM1 IGFBP5 ABCA6 GREB1 COL1A1 COL1A2

3.71e-071851097fb6bd7e849ecf4ed9cd9c4e2a946a2d12d62f804
ToppCellLPS_only-Stromal_mesenchymal-Lung_smooth_muscle-Myofibroblast|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

HTR4 ISM1 ITGA1 IGFBP5 NALCN COL1A1 COL1A2

3.71e-071851097e64e8c98dd88d91f6501d3fb10b60fd2f3c90af3
ToppCellLPS-IL1RA+antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-Myofibroblast|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

HTR4 ISM1 ITGA1 IGFBP5 NALCN COL1A1 COL1A2

3.85e-0718610976add08d4ca019ff2864acdd5ec2c66a59a574591
ToppCell3'-Child04-06-SmallIntestine-Endothelial-lymphatic_endothelial-LEC3_(ADGRG3+)|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

GIMAP4 SLC26A5 CLEC4M EFNA5 ACKR2 SLC24A1 GPRC5B

3.85e-07186109730dd4164c101006c8d95922d89652b82dbe4b5ea
ToppCell5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-Adventitial_fibroblasts_L.2.1.4.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CXCL14 DLK1 IGFBP5 ABCA6 GREB1 COL1A1 COL1A2

3.85e-07186109707d94d5d1c2fe7bb909a07ca81058a0eabc65c60
ToppCellLPS-IL1RA-Stromal_mesenchymal-Lung_smooth_muscle-Myofibroblast|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

HTR4 ISM1 EFNA5 IGFBP5 NALCN COL1A1 COL1A2

4.14e-0718810973177b2c1723268d330d3e9f24f9e24492ace6286
ToppCellLPS-antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-Myofibroblast|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

HTR4 ISM1 EFNA5 IGFBP5 NALCN COL1A1 COL1A2

4.14e-071881097293f2fa99f5f96aa7fd2b2a5cc94ff60eeaabe11
ToppCelldroplet-Lung-nan-18m-Endothelial-Lymphatic_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SUSD4 CELSR1 IGFBP5 TRPV6 ATP2B4 GPRC5B EPHB1

4.14e-071881097a6ed43fdd42d681c9fbb2fb368947ab7e41d8d7c
ToppCelldroplet-Lung-nan-18m-Endothelial-endothelial_cell_of_lymphatic_vessel|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SUSD4 CELSR1 IGFBP5 TRPV6 ATP2B4 GPRC5B EPHB1

4.14e-07188109754550313db78b3b5b572fa1e67092c8f6f33aab5
ToppCelldroplet-Kidney-KIDNEY-30m-Mesenchymal-nan|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DDR2 CXCL14 DLK1 RNASE4 NALCN ABCA6 COL1A1

4.29e-071891097544d95df910f1b276995624509a7e41b219baca0
ToppCellMatrixFB-Fibroblast-C|MatrixFB / shred on cell class and cell subclass (v4)

CXCL14 DLK1 RNASE4 IGFBP5 PRCP COL1A1 COL1A2

4.44e-071901097d0106f7a21292f0b96ce4337ec3efbb1bd78dd0a
ToppCellILEUM-non-inflamed-(7)_Endothelial_cell-(7)_Lymphatics|(7)_Endothelial_cell / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

SUSD4 SLC38A4 SIRPA CLEC4M EFNA5 ABCA6 SLC24A1

4.44e-0719010979ce301841ce9486701fa28eb2a9929e35d476878
ToppCellPSB-critical-LOC-Lymphoid-NK|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

GIMAP4 CD52 DOCK8 ITGA1 PRF1 CD53 LY9

4.44e-071901097e1b5d76edd4c1b95c0a7b94284a65043ab895e67
ToppCellLPS_only-Stromal_mesenchymal-Lung_smooth_muscle|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

HTR4 ISM1 ITGA1 IGFBP5 NALCN COL1A1 COL1A2

4.60e-07191109708042952431ca1a6fd7dfc13f36eb28643979598
ToppCellPCW_10-12-Hematologic_ErythroMegGranulo-Hem_Granulocytic-im_mast/basophil_(18)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

SPINK2 DOCK8 LAPTM5 CD84 DEFA4 CD53 LY9

4.60e-07191109747f20686001f945bc31d5a0b974958e4009edb34
ToppCellASK454-Mesenchymal|ASK454 / Donor, Lineage and Cell class of Lung cells from Dropseq

SLC38A4 DDR2 ITGA1 IGFBP5 ABCA6 COL1A1 COL1A2

4.60e-071911097e30ae7a12439f8a79820b13f03e822c1223fd0cb
ToppCellfacs-Lung-3m-Mesenchymal-myofibroblast|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

DDR2 ISM1 TGFBI IGFBP5 ATP2B4 COL1A1 COL1A2

4.60e-071911097fd8331c7abdd999f55ba43d307945c6abfccbf84
ToppCellASK454-Mesenchymal-Fibroblast|ASK454 / Donor, Lineage and Cell class of Lung cells from Dropseq

SLC38A4 DDR2 ITGA1 IGFBP5 ABCA6 COL1A1 COL1A2

4.60e-0719110971726add3f392a061536b7aff72ba84303f4a0b1f
ToppCellPCW_13-14-Hematologic_ErythroMegGranulo-Hem_Granulocytic-im_mast/basophil_(18)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

CD52 SPINK2 DOCK8 LAPTM5 CD84 CD53 LY9

4.60e-07191109714b11244c330cc4fe897253aaaf0df80caa01a55
ToppCellPCW_07-8.5-Immune_Lymphocytic|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

CD52 SPINK2 DOCK8 LAPTM5 PRF1 CD53 LY9

4.60e-0719110978911b88f70e5deed027177be2e6745b80308616b
ToppCellNasal_Brush-Immune-Neutrophils|Nasal_Brush / Tissue, Lineage and Cell class of Lung Cells from 10X

GIMAP4 CD52 DOCK8 SIRPA CD84 TGFBI CD53

4.77e-07192109720a7f7beb01df1c4f915ec2f9b5a9dbcab157187
ToppCell367C-Endothelial_cells-Endothelial-F_(Lymphatics)|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)

SLC38A4 SLC22A23 LAPTM5 EFNA5 IGFBP5 ACKR2 SLC24A1

4.77e-0719210975e709c0714e8eba27e03a6def0544256bedb3ced
ToppCell368C-Endothelial_cells-Endothelial-F_(Lymphatics)|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)

SLC38A4 SIRPA LAPTM5 EFNA5 IGFBP5 ACKR2 SLC24A1

4.77e-071921097b016e229300c183e14c0e2bba494bf49c7899112
ToppCellLPS-IL1RA+antiTNF-Stromal_mesenchymal-Lung_smooth_muscle|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

HTR4 DDR2 ISM1 ITGA1 IGFBP5 COL1A1 COL1A2

4.77e-071921097992d08092edbc68c47b945deb8708379738c239a
ToppCell368C-Endothelial_cells-Endothelial-F_(Lymphatics)-|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)

SLC38A4 SIRPA LAPTM5 EFNA5 IGFBP5 ACKR2 SLC24A1

4.77e-071921097ac96831492c62ad9e1f7d0b764fbdf7d8a189ad9
ToppCell367C-Endothelial_cells-Endothelial-F_(Lymphatics)-|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)

SLC38A4 SLC22A23 LAPTM5 EFNA5 IGFBP5 ACKR2 SLC24A1

4.77e-0719210975f4f44f15d3a2846981e68296643a4634930a211
ToppCelldroplet-Kidney-nan-18m-Mesenchymal-fibroblast|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DEFB104A DDR2 CXCL14 RNASE4 ABCA6 COL1A1 COL1A2

4.77e-07192109784149a5c6c3b3c9b86aed77cf8e72d99ef099fab
ToppCellNS-control-d_0-4-Lymphoid-Treg|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

GIMAP4 CD52 ITGA1 LAPTM5 CD84 CD53 LY9

4.77e-071921097ef252dd9df161f665f53c047c0514381f80d6683
ToppCellPCW_07-8.5-Immune_Lymphocytic-Immune_Lymphocytic_NK/ILC|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

CD52 SPINK2 DOCK8 LAPTM5 PRF1 CD53 LY9

4.77e-0719210976eadf0f37beae22838e930ad897a9b89e5e12cdb
ToppCellfacs-Lung-EPCAM-18m|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CD52 ISM1 CXCL14 LAPTM5 RNASE4 CD53 COL1A2

4.94e-071931097b9ac74357435f2f24aaede62b2a1d31b5d96a12c
ToppCelltumor_Lung-Fibroblasts-Undetermined|Fibroblasts / Location, Cell class and cell subclass

CD52 DOCK8 LAPTM5 CD84 PRF1 CD53 LY9

4.94e-0719310978cc7172c327a9cf6823e1a35322a4e5960826ec8
ToppCellE15.5-Mesenchymal-myocytic_cell|E15.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

DDR2 ITGA1 TGFBI OPTC ATP2B4 COL1A1 COL1A2

4.94e-0719310973316d6a39abb6a518d45b846254325fc7a8b2035
ToppCelldroplet-Lung-18m-Mesenchymal-fibroblast-adventitial_fibroblast|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

DDR2 ISM1 CXCL14 RNASE4 EFNA5 COL1A1 COL1A2

4.94e-071931097fe9720185929ef849edd1b8eb4854306b392e5a2
ToppCellCOVID-19-Fibroblasts-Other_FB|COVID-19 / group, cell type (main and fine annotations)

DDR2 ISM1 ITGA1 NALCN ABCA6 COL1A1 COL1A2

4.94e-071931097e6b75be08e33c1de079fb5c02f0b4468128b369c
ToppCell5'-Adult-SmallIntestine-Endothelial-lymphatic_endothelial-LEC3_(ADGRG3+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SLC26A5 CLEC4M EFNA5 NALCN ACKR2 SLC24A1 GPRC5B

4.94e-071931097bd0027fa97de41ae22ff64a61c8e217496f122ca
ToppCellT_cell|World / shred by cell class for nasal brushing

GIMAP4 CD52 ITGA1 LAPTM5 PRF1 CD53 LY9

4.94e-07193109707530bbeffd5951880ed6ea50a962c102b05ccc2
ToppCellNS-moderate-d_07-13-Lymphoid-Treg|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

GIMAP4 ABHD14A CD52 ITGA1 PRF1 CD53 LY9

4.94e-0719310976115d43017070a78d335687bd039c08f00f77029
ToppCellBrain_organoid-organoid_Kanton_Nature-Organoid-2M-Mesenchymal|Organoid-2M / Sample Type, Dataset, Time_group, and Cell type.

DDR2 CXCL14 TGFBI TRPM3 PRAP1 COL1A1 COL1A2

5.11e-071941097638b9fdce64ed00243b5303800ec66207d5fd640
ToppCellBrain_organoid-organoid_Kanton_Nature-Organoid-2M-Mesenchymal-choroid_plexus/mesenchymal-like_cells|Organoid-2M / Sample Type, Dataset, Time_group, and Cell type.

DDR2 CXCL14 TGFBI TRPM3 PRAP1 COL1A1 COL1A2

5.11e-071941097e9868c22934b6c0ac35e3e8270ec0b671bc6582a
ToppCell3'-GW_trimst-2-SmallIntestine-Hematopoietic-T_cells-Activated_T|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

GIMAP4 CD52 SPINK2 DOCK8 LAPTM5 PRF1 CD53

5.11e-0719410976385cf2a1529d2e225e407c33da959fccaaca3a4
ToppCell3'-Broncho-tracheal-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-Adventitial_fibroblasts_L.2.1.0.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DDR2 CXCL14 IGFBP5 ABCA6 GREB1 COL1A1 COL1A2

5.11e-07194109735b30bc954750e939f81a9a7498b8bc2ce69a299
ToppCelldroplet-Bladder-Unstain-18m-Epithelial-bladder_cell|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DDR2 ISM1 CXCL14 PKD1 GREB1 COL1A1 COL1A2

5.11e-071941097ee6b5fb4e993a4c0dc556091b8fefd56bdc70d8f
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

DDR2 ITGA1 TGFBI IGFBP5 ABCA6 COL1A1 COL1A2

5.11e-071941097240d122dcb9dd1ab2867503ad85869853adcacae
ComputationalHeart genes.

CD52 GBF1 HTR4 TP53I11 DLK1 DEFA3 TGFBI PRF1 PKD1 ACKR2 COL1A2

1.85e-054236011MODULE_60
ComputationalFetal liver genes - metabolism and xenobiotics.

CYP2B6 HTR4 DLK1 F12 LAPTM5 DEFA3 TGFBI RNASE4 IGSF1 COL1A1 COL1A2

3.48e-054536011MODULE_24
ComputationalHeart, liver, kidney and pancreas metabolic and xenobiotic response genes.

CYP2B6 HTR4 DLK1 F12 LAPTM5 DEFA3 TGFBI RNASE4 PRF1 ASIP IGSF1 GPRC5B COL1A1 COL1A2

1.55e-048356014MODULE_88
ComputationalGenes upregulated in subsets of cells of a given type within various tumors

TGFBI IGFBP5 COL1A1 COL1A2

1.67e-0450604GAVISH_3CA_MALIGNANT_METAPROGRAM_12_EMT_1
ComputationalGenes upregulated in subsets of cells of a given type within various tumors

CXCL14 IGFBP5 COL1A1 COL1A2

1.67e-0450604GAVISH_3CA_METAPROGRAM_FIBROBLASTS_CAF_1
ComputationalGenes in the cancer module 55.

CYP2B6 HTR4 DLK1 F12 LAPTM5 DEFA3 TGFBI RNASE4 PRF1 ASIP IGSF1 COL1A1 COL1A2

5.53e-048326013MODULE_55
ComputationalImmune (humoral) and inflammatory response.

GIMAP4 CD52 HTR4 DEFB104A LAPTM5 DEFA3 TGFBI PRF1 CD53 COL1A2

7.98e-045466010MODULE_84
DrugAC1MO44M

DEFB104A CXCL14 SIRPA DEFA1 DEFA3 DEFA4 ACKR2

7.14e-08771067CID003363163
DrugCotinine (-) [486-56-6]; Up 200; 22.6uM; MCF7; HT_HG-U133A

CD52 DDX60 IFNA2 DEFA4 IGFBP5 CD53 SLC24A1 SERPINA7 COL1A1

3.61e-0719710695246_UP
Drug4-carbethoxyhexafluorobutyryl chloride

DEFA1 DEFA3 ACKR2

9.74e-0751063CID000161251
DrugPFPA

DEFA1 DEFA3 PRF1 ACKR2

1.29e-06181064CID000067742
DrugDioxybenzone [131-53-3]; Up 200; 16.4uM; MCF7; HT_HG-U133A

HFE HTR4 GPR37 DDX60 IGFBP5 CD53 LY9 COL1A1

3.55e-0619410685699_UP
DrugOxamniquine [21738-42-1]; Up 200; 14.4uM; PC3; HT_HG-U133A

HFE CYP2B6 TP53I11 HUWE1 THPO TRPM3 GNRH2 EPHB1

4.45e-0620010684006_UP
DrugAC1NRBPT

BGLAP TGFBI IGFBP5 PKD1 GNRH2 COL1A1 COL1A2

1.09e-051621067CID005288571
DrugAC1Q4I4X

DEFA1 DEFA3 ACKR2

1.15e-05101063CID000122085
Drug2-methoxyethoxy)acetic acid

DEFA1 DEFA3

2.15e-0521062CID000027642
Drug1,2,5,6-tetramethylnaphthalene

DEFA1 DEFA3

2.15e-0521062CID006427081
Drug1,4,5-trimethylnaphthalene

DEFA1 DEFA3

2.15e-0521062CID000016478
Drugp-sulfobenzyl alcohol

DEFA1 DEFA3

2.15e-0521062CID000441138
Drug5'-methylthioadenosine

COL1A1 COL1A2

2.15e-0521062ctd:C008500
DrugMK-677

DLK1 BGLAP IGFBP5 GNRH2 COL1A1

2.32e-05731065CID000178024
Drugpyrachlostrobin

DDR2 PM20D1 SLC10A3 DLK1 ITGA1 LAPTM5 CD84 CELSR1 RNASE4 IGFBP5 SLC2A6 CD53 TRPV6 COL1A1

2.40e-0581110614ctd:C513428
DrugT-E-A-T

DLK1 BGLAP IGFBP5 GNRH2 COL1A1

2.83e-05761065CID000086807
DrugNortriptyline hydrochloride [894-71-3]; Up 200; 13.4uM; MCF7; HT_HG-U133A

HFE TP53I11 HUWE1 RNASE4 IGFBP5 SLC2A6 COL1A1

2.96e-0518910676003_UP
Drugdenatonium

BGLAP OPTC COL1A1

3.44e-05141063CID000019518
DrugCarbetapentane citrate [23142-01-0]; Up 200; 7.6uM; MCF7; HT_HG-U133A

HFE CD52 TP53I11 HUWE1 CLEC4M IGFBP5 EPHB1

3.50e-0519410675610_UP
DrugEucatropine hydrochloride [536-93-6]; Up 200; 12.2uM; HL60; HT_HG-U133A

HFE HTR4 HUWE1 CLEC4M THPO IGFBP5 TRPM3

3.86e-0519710672556_UP
DrugAmyleine hydrochloride [532-59-2]; Up 200; 14.8uM; MCF7; HT_HG-U133A

HFE GPR37 CD84 IGFBP5 SLC24A1 ATP2B4 COL1A1

3.86e-0519710671491_UP
DrugDizocilpine maleate [77086-22-7]; Up 200; 11.8uM; PC3; HT_HG-U133A

HFE TMEM53 SPINK2 GPR85 IFNA2 ACKR2 SLC24A1

3.99e-0519810675746_UP
DrugNeomycin sulfate [1405-10-3]; Up 200; 4.2uM; PC3; HT_HG-U133A

HFE SPINK2 GPR85 TP53I11 IFNA2 IGFBP5 COL1A2

3.99e-0519810675867_UP
DrugLobelanidine hydrochloride [6112-86-3]; Up 200; 10.6uM; MCF7; HT_HG-U133A

HTR4 TP53I11 DEFA4 IGFBP5 CD53 IGSF1 COL1A1

3.99e-0519810675500_UP
DrugH-7 dihydrochloride; Up 200; 100uM; PC3; HT_HG-U133A

HFE GPR85 TP53I11 IFNA2 LAPTM5 TGFBI PRF1

4.12e-0519910675968_UP
DrugPyrantel tartrate [33401-94-4]; Up 200; 11.2uM; MCF7; HT_HG-U133A

CD52 SPINK2 TRPM3 GRAMD1C ATP2B4 COL1A1 EPHB1

4.25e-0520010675513_UP
DrugLY 294002; Up 200; 0.1uM; PC3; HT_HG-U133A

CYP2B6 HTR4 HUWE1 CD84 EFNA5 CD53 COL1A1

4.25e-0520010674440_UP
DrugTc-99m HMDP

HFE BGLAP

6.42e-0531062CID000123801
Drug4-ethylbenzoate

DEFA1 DEFA3

6.42e-0531062CID000012086
Drugneoeriocitrin

BGLAP COL1A1

6.42e-0531062ctd:C553460
DrugBac7

DEFB104A DEFA1 DEFA3 DEFA4

6.79e-05471064CID000163998
DrugGHRP-6

DLK1 BGLAP IGFBP5 GNRH2 COL1A1

8.69e-05961065CID004345065
DrugAC1Q5HK6

CYP2B6 HTR4 PF4V1 BGLAP TGFBI DEFA4 IGFBP5 GNRH2 COL1A1 COL1A2

1.17e-0450110610CID000003640
Drugticlopidine

CYP2B6 PF4V1 THPO COL1A1 COL1A2

1.21e-041031065CID000005472
Drugtrifluoroacetamide

DEFA1 DEFA3 ACKR2

1.23e-04211063CID000067717
DrugO-C-O

BGLAP EFNA5 GNRH2 COL1A1 COL1A2

1.27e-041041065CID000014785
DrugCollagenase

COL1A1 COL1A2

1.28e-0441062DB00048
Drugtopanol A

DEFA1 DEFA3

1.28e-0441062CID000015884
Drug4-fluorobenzoyl chloride

DEFA1 DEFA3

1.28e-0441062CID000067879
DrugAC1L3OZP

DEFA1 DEFA3

1.28e-0441062CID000092862
Drugsperabillin A

DEFA1 DEFA3

1.28e-0441062CID006441177
Drugxenognosin B

DEFA1 DEFA3

1.28e-0441062CID005280551
Drugoleth-3-phosphate

CD52 SIRPA CD53 ATP2B4

1.77e-04601064CID000021452
DrugRescinnamin [24815-24-5]; Up 200; 6.4uM; MCF7; HT_HG-U133A

HFE DDX60 IGFBP5 SLC2A6 PRF1 COL1A1

2.05e-0418110662785_UP
DrugAC1O5T5C

DEFA1 DEFA3

2.13e-0451062CID006440182
Drugdipropylacetal

DEFA1 DEFA3

2.13e-0451062CID000066929
Drug1kwq

DLK1 EFNA5 TRPV6

2.36e-04261063CID003092847
Drugfluphenazine dihydrochloride; Up 200; 10uM; MCF7; HT_HG-U133A

GPR85 RNASE4 TRPM3 CD53 COL1A1 COL1A2

2.38e-0418610665597_UP
DrugLevonordefrin [829-74-3]; Up 200; 21.8uM; PC3; HT_HG-U133A

HFE CYP2B6 HTR4 GPR85 ITGA1 CD53

2.45e-0418710665854_UP
DrugFlavonoids

CYP2B6 SLC38A4 SLC26A5 DLK1 BGLAP LAPTM5 SLC38A2 THPO IGFBP5 GUCY2C PKD1 TRPV6 SLC24A1 ATP2B4 COL1A2

2.46e-04113610615ctd:D005419
DrugRescinnamin [24815-24-5]; Up 200; 6.4uM; MCF7; HT_HG-U133A

HFE CD52 HTR4 IGFBP5 TRPM3 SLC2A6

2.52e-0418810664386_UP
Drug1 2M

HUWE1 IGFBP5 EPHB1

2.64e-04271063CID005225083
DrugDicumarol [66-76-2]; Up 200; 11.8uM; HL60; HT_HG-U133A

HFE CD52 TP53I11 RNASE4 IGFBP5 GNRH2

2.82e-0419210662561_UP
Drugrapamycin; Up 200; 0.1uM; MCF7; HT_HG-U133A_EA

HFE CD52 HUWE1 GREB1 GRAMD1C COL1A1

2.90e-041931066921_UP
DrugPropafenone hydrochloride [34183-22-7]; Up 200; 10.6uM; MCF7; HT_HG-U133A

DDX60 CLEC4M CD84 RNASE4 TRPM3 GREB1

2.90e-0419310665437_UP
DrugNSC19448

BGLAP TGFBI EFNA5 GREB1 GNRH2 COL1A1 COL1A2

2.93e-042731067CID000003054
DrugBM-11

DEFA1 DEFA3 DEFA4

2.95e-04281063CID003036083
DrugIopromide [73334-07-3]; Up 200; 5uM; MCF7; HT_HG-U133A

HFE TP53I11 IGFBP5 ACKR2 GREB1 SLC24A1

2.98e-0419410663481_UP
DrugTrichlormethiazide [133-67-5]; Up 200; 10.6uM; HL60; HT_HG-U133A

HFE DDR2 HUWE1 ZNF34 EFNA5 COL1A2

2.98e-0419410662998_UP
DrugTropicamide [1508-75-4]; Up 200; 14uM; MCF7; HT_HG-U133A

HFE CD52 TP53I11 F12 SLC24A1 COL1A1

2.98e-0419410664744_UP
DrugMeropenem [96036-03-2]; Up 200; 10.4uM; PC3; HT_HG-U133A

HFE TMEM53 DDX60 TP53I11 ITGA1 COL1A1

2.98e-0419410665824_UP
Drugbutein; Down 200; 10uM; PC3; HG-U133A

TRHDE HFE CYP2B6 GPR37 TRPM3 PRF1

2.98e-041941066582_DN
DrugEthoxyquin [91-53-2]; Up 200; 18.4uM; MCF7; HT_HG-U133A

HFE HTR4 DDX60 GREB1 SLC24A1 COL1A1

2.98e-0419410663846_UP
DrugLY-171,883; Down 200; 1uM; MCF7; HG-U133A

HFE HTR4 TP53I11 IGFBP5 TRPM3 ASIP

2.98e-041941066222_DN
DrugAmprolium hydrochloride [137-88-2]; Up 200; 12.6uM; PC3; HG-U133A

TRHDE HFE HTR4 DDX60 TGFBI CD53

3.06e-0419510661898_UP
DrugProcarbazine hydrochloride [366-70-1]; Up 200; 15.6uM; MCF7; HT_HG-U133A

HFE CYP2B6 SPINK2 IFNA2 PRF1 COL1A2

3.06e-0419510665452_UP
Drugchlorpromazine hydrochloride; Up 200; 1uM; HL60; HT_HG-U133A

HFE CELSR1 IGFBP5 ATP2B4 COL1A1 COL1A2

3.06e-0419510666176_UP
DrugXamoterol hemifumarate [73210-73-8]; Up 200; 5uM; MCF7; HT_HG-U133A

HFE CD52 SLC24A1 ATP2B4 COL1A1 COL1A2

3.06e-0419510663401_UP
DrugTobramycin [32986-56-4]; Up 200; 8.6uM; MCF7; HT_HG-U133A

CD52 CYP2B6 DLK1 LAPTM5 TRPV6 COL1A1

3.06e-0419510664162_UP
DrugPramoxine hydrochloride [637-58-1]; Up 200; 12.2uM; MCF7; HT_HG-U133A

CELSR1 IGFBP5 TRPM3 CD53 LY9 SLC24A1

3.06e-0419510664368_UP
DrugFamprofazone [22881-35-2]; Up 200; 10.6uM; MCF7; HT_HG-U133A

TMEM53 DDX60 RNASE4 PRF1 ACKR2 COL1A1

3.06e-0419510663834_UP
DrugCimetidine [51481-61-9]; Up 200; 15.8uM; PC3; HT_HG-U133A

HFE CD52 ATP2B4 COL1A1 COL1A2 EPHB1

3.06e-0419510664063_UP
DrugRibostamycin sulfate salt [53797-35-6]; Up 200; 7.2uM; HL60; HT_HG-U133A

HFE TP53I11 IGFBP5 ACKR2 SLC24A1 GRAMD1C

3.06e-0419510662705_UP
DrugBambuterol hydrochloride [81732-46-9]; Up 200; 10uM; MCF7; HT_HG-U133A

HFE HTR4 GPR85 IGFBP5 ACKR2 SLC24A1

3.06e-0419510663199_UP
DrugDO 897/99; Up 200; 8.2uM; MCF7; HT_HG-U133A

HFE CD52 HTR4 SLC24A1 COL1A1 EPHB1

3.15e-0419610662877_UP
DrugSulfisoxazole [127-69-5]; Up 200; 15uM; MCF7; HT_HG-U133A

CYP2B6 GPR37 HUWE1 DEFA4 THPO ATP2B4

3.15e-0419610665622_UP
Drug17-AAG; Down 200; 1uM; PC3; HG-U133A

HFE TP53I11 CD84 DEFA4 TRPM3 ASIP

3.15e-041961066432_DN
DrugBrinzolamide [138890-62-7]; Up 200; 10.4uM; PC3; HT_HG-U133A

HTR4 GPR85 CD84 DEFA4 IGFBP5 COL1A1

3.15e-0419610666670_UP
DrugCetirizine dihydrochloride [83881-52-1]; Up 200; 8.6uM; PC3; HT_HG-U133A

HFE THPO IGSF1 LY9 SLC24A1 EPHB1

3.15e-0419610664231_UP
DrugSulfinpyrazone [57-96-5]; Down 200; 9.8uM; MCF7; HT_HG-U133A

TP53I11 LAPTM5 IGFBP5 CD53 TRPV6 COL1A1

3.15e-0419610663192_DN
DrugHesperetin [520-33-2]; Up 200; 13.2uM; HL60; HG-U133A

HTR4 SLC10A3 CLEC4M CD84 PRF1 IGSF1

3.15e-0419610662031_UP
Drugflufenacet

DEFA1 DEFA3

3.18e-0461062CID000086429
Drug2-phenyl-4-(3-pyridin-2-yl-1H-pyrazol-4-yl)pyridine

COL1A1 COL1A2

3.18e-0461062ctd:C502971
Drug2,2',4,4',5-pentachlorobiphenyl

CYP2B6 SERPINA7

3.18e-0461062ctd:C500336
DrugKathon

SIRPA THPO

3.18e-0461062CID000033528
DrugBoron

BGLAP COL1A1

3.18e-0461062ctd:D001895
Drugtestosterone acetate

DEFA1 DEFA3

3.18e-0461062CID000092145
DrugRemifemin

BGLAP COL1A2

3.18e-0461062ctd:C073419
DrugAR-L57

DEFA1 DEFA3

3.18e-0461062CID000156890
Drugvitamin D3

CYP2B6 BGLAP TGFBI TRPV6 ACKR2 ATP2B4 COL1A1

3.20e-042771067CID000002735
DrugMethyldopa (L,-) [555-30-6]; Up 200; 19uM; MCF7; HT_HG-U133A

HFE HUWE1 THPO IGFBP5 SLC24A1 COL1A1

3.24e-0419710665637_UP
DrugPhentolamine hydrochloride [73-05-2]; Up 200; 12.6uM; PC3; HT_HG-U133A

HFE DEFA4 IGFBP5 GRAMD1C SERPINA7 COL1A1

3.24e-0419710664336_UP
DrugCefotetan [69712-56-7]; Up 200; 7uM; MCF7; HT_HG-U133A

TP53I11 HUWE1 LAPTM5 SLC24A1 GNRH2 EPHB1

3.24e-0419710664116_UP
DrugPhenethicillin potassium salt [132-93-4]; Down 200; 10uM; MCF7; HT_HG-U133A

HTR4 GPR85 TP53I11 GREB1 GRAMD1C COL1A1

3.24e-0419710666105_DN
Drugestradiol, USP; Up 200; 0.1uM; MCF7; HG-U133A

HTR4 SLC2A6 ASIP GNRH2 GPRC5B COL1A2

3.24e-041971066365_UP
DrugPiracetam [7491-74-9]; Up 200; 28.2uM; PC3; HT_HG-U133A

HFE GPR85 LAPTM5 PRF1 GRAMD1C COL1A1

3.24e-0419710665043_UP
DrugMethylhydantoin-5-(D) [55147-68-7]; Up 200; 35uM; MCF7; HT_HG-U133A

HFE CELSR1 IGFBP5 LY9 ATP2B4 EPHB1

3.24e-0419710664113_UP
DrugEsculin Hydrate [531-75-9]; Up 200; 11.8uM; MCF7; HT_HG-U133A

CD52 DDX60 TP53I11 ACKR2 SLC24A1 COL1A1

3.24e-0419710663390_UP
DrugAmiprilose hydrochloride [60414-06-4]; Up 200; 11.8uM; MCF7; HT_HG-U133A

HFE HTR4 GPR37 ACKR2 SLC24A1 EPHB1

3.24e-0419710663339_UP
DrugLactobionic acid [96-82-2]; Up 200; 11.2uM; PC3; HT_HG-U133A

TMEM53 ITGA1 THPO TRPM3 LY9 COL1A2

3.24e-0419710666605_UP
DiseaseEHLERS-DANLOS SYNDROME, ARTHROCHALASIA TYPE

COL1A1 COL1A2

1.18e-0521022C0268345
DiseaseEHLERS-DANLOS SYNDROME, ARTHROCHALASIA TYPE, 1

COL1A1 COL1A2

1.18e-0521022C4551623
DiseaseOsteogenesis imperfecta with normal sclerae, dominant form

COL1A1 COL1A2

1.18e-0521022cv:C0268363
DiseaseOsteogenesis imperfecta type III

COL1A1 COL1A2

1.18e-0521022cv:C0268362
DiseaseOsteogenesis imperfecta, perinatal lethal

COL1A1 COL1A2

1.18e-0521022cv:C0268358
DiseaseOSTEOGENESIS IMPERFECTA, TYPE III

COL1A1 COL1A2

1.18e-0521022259420
Diseaseosteogenesis imperfecta type 3 (is_implicated_in)

COL1A1 COL1A2

1.18e-0521022DOID:0110339 (is_implicated_in)
Diseaseosteogenesis imperfecta type 4 (is_implicated_in)

COL1A1 COL1A2

1.18e-0521022DOID:0110340 (is_implicated_in)
Diseaseosteogenesis imperfecta type 2 (is_implicated_in)

COL1A1 COL1A2

1.18e-0521022DOID:0110341 (is_implicated_in)
DiseaseOSTEOGENESIS IMPERFECTA, TYPE IV

COL1A1 COL1A2

1.18e-0521022166220
DiseaseOSTEOGENESIS IMPERFECTA, TYPE II

COL1A1 COL1A2

1.18e-0521022166210
Diseaseosteogenesis imperfecta (is_implicated_in)

COL1A1 COL1A2

3.54e-0531022DOID:12347 (is_implicated_in)
Diseaseosteogenesis imperfecta type 3 (implicated_via_orthology)

COL1A1 COL1A2

3.54e-0531022DOID:0110339 (implicated_via_orthology)
DiseaseOSTEOPOROSIS

COL1A1 COL1A2

7.07e-0541022166710
DiseaseLiver Cirrhosis, Experimental

SLC22A23 SLC44A2 IFNA2 LAPTM5 RNASE4 PLA2G12A CD53 SERPINA7 COL1A1 CNDP1 COL1A2

7.69e-0577410211C0023893
DiseaseHeart valve disease

BGLAP COL1A1 COL1A2

9.84e-05261023C0018824
DiseaseOsteogenesis imperfecta, dominant perinatal lethal

COL1A1 COL1A2

1.18e-0451022C0268358
Diseaseosteogenesis imperfecta (implicated_via_orthology)

COL1A1 COL1A2

1.18e-0451022DOID:12347 (implicated_via_orthology)
DiseaseLobstein Disease

COL1A1 COL1A2

1.18e-0451022C0023931
DiseaseEhlers-Danlos Syndrome

COL1A1 COL1A2

1.18e-0451022C0013720
Diseaseosteoarthritis (is_implicated_in)

HFE DDR2 BGLAP

1.23e-04281023DOID:8398 (is_implicated_in)
Diseaseosteoporosis (is_implicated_in)

BGLAP COL1A1 COL1A2

1.68e-04311023DOID:11476 (is_implicated_in)
DiseaseOsteoporosis

COL1A1 COL1A2

1.76e-0461022cv:C0029456
DiseaseEhlers-Danlos syndrome (implicated_via_orthology)

COL1A1 COL1A2

1.76e-0461022DOID:13359 (implicated_via_orthology)
DiseaseNEURAL TUBE DEFECTS, SUSCEPTIBILITY TO

VANGL2 CELSR1

3.27e-0481022C3891448
Diseasefactor VIII measurement

F12 SLC38A2 SLC2A6

3.61e-04401023EFO_0004630
Diseaseneutrophil measurement

HTR4 DEFA1 DEFA3 DEFA4 TMEM41B

3.82e-041771025EFO_0803548
DiseaseThrombocytosis, Autosomal Dominant

IFNA2 THPO

4.19e-0491022C3489628
DiseaseOsteogenesis imperfecta type IV (disorder)

COL1A1 COL1A2

5.23e-04101022C0268363
Diseasebeta thalassemia (is_implicated_in)

HFE COL1A1

5.23e-04101022DOID:12241 (is_implicated_in)
Diseaseankyrin-2 measurement

OPTC ATP2B4

5.23e-04101022EFO_0021874
DiseaseEarly Pregnancy Loss

CD84 TGFBI COL1A1 COL1A2

5.67e-041091024C3830362
DiseaseSpontaneous abortion

CD84 TGFBI COL1A1 COL1A2

5.67e-041091024C0000786
DiseaseMiscarriage

CD84 TGFBI COL1A1 COL1A2

5.67e-041091024C4552766
DiseaseAbortion, Tubal

CD84 TGFBI COL1A1 COL1A2

5.67e-041091024C0000822
Diseasemonocyte count

CD52 SPINK2 DOCK8 DDR2 PM20D1 CLEC4M CD84 DEFA3 DEFA4 PKD1 ACKR2 LY9 ATP2B4

6.27e-04132010213EFO_0005091
DiseaseOsteogenesis imperfecta type III (disorder)

COL1A1 COL1A2

6.38e-04111022C0268362
DiseaseDiarrhea

IFNA2 GUCY2C

6.38e-04111022C0011991
Diseasecholesteryl esters to total lipids in small VLDL percentage

TTC39B TMEM116 ABCA6

6.58e-04491023EFO_0022256
Diseaseintracranial aneurysm (is_implicated_in)

PKD1 COL1A2

7.64e-04121022DOID:10941 (is_implicated_in)
DiseaseThrombocythemia, Essential

IFNA2 THPO

7.64e-04121022C0040028
Diseaseplatelet measurement

SPINK2 DOCK8 SIRPA F12 THPO TRPM3

8.05e-043151026EFO_0005036
DiseaseFamilial thoracic aortic aneurysm and aortic dissection

PKD1 COL1A1 COL1A2

8.29e-04531023C4707243
DiseaseOsteogenesis Imperfecta

COL1A1 COL1A2

9.00e-04131022C0029434
Diseaseaplastic anemia (is_implicated_in)

THPO PRF1

9.00e-04131022DOID:12449 (is_implicated_in)
Diseaseicos ligand measurement

DEFA1 DEFA4

9.00e-04131022EFO_0020460
DiseaseHepatitis C

HFE IFNA2

1.21e-03151022C0019196
DiseaseYKL40 measurement

OPTC ATP2B4

1.21e-03151022EFO_0004869
Diseaselifestyle measurement, anxiety disorder measurement

TRHDE SIRPA TRPM3 ACKR2

1.33e-031371024EFO_0007795, EFO_0010724
DiseaseSLAM family member 7 measurement

DDR2 LY9

1.56e-03171022EFO_0008287
DiseaseOral Submucous Fibrosis

COL1A1 COL1A2

1.75e-03181022C0029172
DiseaseAnorexia

HTR4 IFNA2

1.75e-03181022C0003123
Diseasecardiomyopathy (is_implicated_in)

HFE POMT1

1.95e-03191022DOID:0050700 (is_implicated_in)
Diseasesensorineural hearing loss (implicated_via_orthology)

SLC44A4 SLC7A14

1.95e-03191022DOID:10003 (implicated_via_orthology)
DiseaseOsteogenesis imperfecta

COL1A1 COL1A2

2.38e-03211022cv:C0029434
DiseaseLymphoma, Diffuse

IFNA2 PRF1

2.38e-03211022C3714542
DiseaseLow Grade Lymphoma (neoplasm)

IFNA2 PRF1

2.38e-03211022C0079747
DiseaseLymphoma, Intermediate-Grade

IFNA2 PRF1

2.38e-03211022C0079741
DiseaseHigh Grade Lymphoma (neoplasm)

IFNA2 PRF1

2.38e-03211022C0079740
DiseaseDiffuse Mixed-Cell Lymphoma

IFNA2 PRF1

2.38e-03211022C0079757
DiseaseLymphoma, Undifferentiated

IFNA2 PRF1

2.38e-03211022C0024306
DiseaseReticulosarcoma

IFNA2 PRF1

2.38e-03211022C0024302
DiseaseLymphoma, Mixed-Cell

IFNA2 PRF1

2.38e-03211022C0024304
Diseasetotal iron binding capacity

HFE SLC44A4 EPHB1

2.53e-03781023EFO_0006334
DiseaseLymphoma, Non-Hodgkin, Familial

IFNA2 PRF1

2.61e-03221022C4721532
DiseaseLymphoma, Small Noncleaved-Cell

IFNA2 PRF1

2.61e-03221022C0079770
Diseasehypothyroidism (biomarker_via_orthology)

SLC26A5 SERPINA7 COL1A2

2.72e-03801023DOID:1459 (biomarker_via_orthology)
DiseaseSepticemia

IFNA2 TGFBI

3.11e-03241022C0036690
DiseaseSepsis

IFNA2 TGFBI

3.11e-03241022C0243026
DiseaseSevere Sepsis

IFNA2 TGFBI

3.11e-03241022C1719672
DiseasePyemia

IFNA2 TGFBI

3.11e-03241022C0034189
Diseaselymphocyte:monocyte ratio

CD52 DEFA3 PRF1 ACKR2 LY9

3.30e-032881025EFO_0600088

Protein segments in the cluster

PeptideGeneStartEntry
LRALLMVLVFLLVVS

VANGL2

181

Q9ULK5
LLAVTMLAVLLSLRF

TRHDE

51

Q9UKU6
LSGNLLLLMVLLRYV

ACKR2

61

O00590
MALFVRLLALALALA

TGFBI

1

Q15582
MSIFVLLLVLLNVTL

GRAMD1C

561

Q8IYS0
LLMSFFILLLIILLA

CD53

81

P19397
MELSVLLFLALLTGL

CYP2B6

1

P20813
MTIHILILLLLLAFS

ADM5

1

C9JUS6
LLLSVIFNILLSLAM

ATP13A4

971

Q4VNC1
ASRLLLLPRVLLTMA

CUTA

31

O60888
SMLLLDGLIYLLLAL

ABCA6

401

Q8N139
AALLVAFVLLSLVRM

CELSR1

2481

Q9NYQ6
AFVLLSLVRMLRSNL

CELSR1

2486

Q9NYQ6
MTATEALLRVLLLLL

DLK1

1

P80370
AGLLMSALTVFILIL

ATP2B4

366

P23634
MDVTRLLLATLLVFL

ASIP

1

P42127
LMSLGILLLLVSRLL

TP53I11

156

O14683
GAVVLLLLVALLMLR

GUCY2C

441

P25092
SVMALLQALELLLIR

PM20D1

161

Q6GTS8
ALLGLSLLLMLLLYV

ABHD14A

36

Q9BUJ0
MALDYLLLLLLASAV

EPHB1

1

P54762
RPALTLLLLLMAAVV

PLA2G12A

6

Q9BZM1
ILDLIMLILFFLDSL

SLC24A1

566

O60721
VLLFLMLLFVISSIA

SLC24A1

1046

O60721
LQFLSVLSRMLVRLT

GREB1

1356

Q4ZG55
RMLLVLFLLLPILSS

DDR2

6

Q16832
MRATAIVLLLALTLA

SPINK9

1

Q5DT21
RILETLVMLLLLALL

LMBR1

146

Q8WVP7
HFPLSITLVLRLMLL

DDX60

1361

Q8IY21
FPLSITLVLRLMLLA

DDX60L

1346

Q5H9U9
RATRQEMLFLALLLL

PF4V1

11

P10720
MRLLAFLSLLALVLQ

OPTC

1

Q9UBM4
ILLSYALILRAMLVI

OR51I1

216

Q9H343
SLLALAMLQLSLRRL

SLC10A3

426

P09131
MAARLLLLGILLLLL

PRF1

1

P14222
MGRRALLLLLLSFLA

PRCP

1

P42785
MVLLTAVLLLLAAYA

IGFBP5

1

P24593
RPALLLLMLLQTAVL

HFE

6

Q30201
LQLLVFTALAILIMR

DPY19L2

541

Q6NUT2
LLSAFAGLLLLMLLI

ITGA1

1146

P56199
VRLLSVLIAALTMDL

SLC2A6

321

Q9UGQ3
MLLLAVLNFTALLIE

HUWE1

91

Q7Z6Z7
TLELMSFILALFTLI

OR6C76

191

A6NM76
VSMRLLAAALLLLLL

CXCL14

11

O95715
MALSVLRLALLLLAV

SPINK2

1

P20155
MSAVGLVLLVLALRL

PKD1L2

1

Q7Z442
MRALTLLALLALAAL

BGLAP

1

P02818
GALITLLLMLILLVR

GPRC5B

66

Q9NZH0
RLMLLESVLIFFNLL

POMT1

151

Q9Y6A1
VLRLLLVTMGLLFVL

FRMD5

501

Q7Z6J6
LVTMGLLFVLLLLLI

FRMD5

506

Q7Z6J6
MLSFVDTRTLLLLAV

COL1A2

1

P08123
IRLSLIMQLVALLLV

IGSF1

521

Q8N6C5
ALLARMSRLLLLLLL

GPR37

6

O15354
MRTLAILAAILLVAL

DEFA1

1

P59665
LPTLISMRLEFLRIL

DOCK8

1086

Q8NF50
MRTLAILAAILLVAL

DEFA3

1

P59666
GLLLFLLSLMTLTLF

MT-CYB

231

P00156
VLLVLVLLILSMRRH

CDH20

631

Q9HBT6
MQRLVLLLAISLLLY

DEFB104A

1

Q8WTQ1
ARNIVLSFMLLLLLL

BCE1

66

O60756
VLLTFLSTVILMAIL

HTR4

21

Q13639
MKRFLFLLLTISLLV

CD52

1

P31358
MRLHLLLLILLLFSI

DEFB109B

1

Q30KR1
MALTFALLVALLVLS

IFNA2

1

P01563
VLQTSLLFLLMGLRA

LY9

31

Q9HBG7
PSRLLAILLFLLAML

EFNA5

211

P52803
ISAQVLLSLRILLLM

GBF1

1216

Q92538
GFMLLLALILLATQL

GPR85

186

P60893
SLLFIILLRFLAGIM

SLC44A2

246

Q8IWA5
LAVLEAILLLMLIFL

SLC44A4

316

Q53GD3
MASSRRGLLLLLLLT

GNRH2

1

O43555
ISLMTLLLFVVLLAF

EQTN

186

Q9NQ60
MRIIALLAAILLVAL

DEFA4

1

P12838
MVRLAAELLLLLGLL

ISM1

1

B1AKI9
MRRLLLVTSLVVVLL

PRAP1

1

Q96NZ9
LRSLLVYMLFLLVTL

PKD1

3671

P98161
TSLLAMTRTFLIFRL

OR1P1

166

Q8NH06
MRALLLLGFLLVSLE

F12

1

P00748
LIMFILTATLLILSL

TAS2R39

221

P59534
LIMFILAATLLILSL

TAS2R40

206

P59535
VMLLILSLFLLIFDS

TAS2R42

131

Q7RTR8
LAILLILLFTMLLRL

SERTM2

46

A0A1B0GWG4
LMAVILSVTLLLIFS

RNF183

166

Q96D59
IMTALQIASFILLRL

GIMAP4

311

Q9NUV9
SFLLITMLFIISLSL

LAPTM5

66

Q13571
LLLFMILTALASLLQ

SLC22A23

496

A1A5C7
LASLMILLVILATGF

SLC26A5

416

P58743
TLLVALLMAALYLVR

SIRPA

381

P78324
MALRRLLLLLLLSLE

SHISA6

1

Q6ZSJ9
LLSVLAMFFLLVLIL

CD84

226

Q9UIB8
LLIFLITMLILVTAN

MT-ND5

121

P03915
ILFIIMLLAVAILSL

SLC38A4

106

Q969I6
LVLQLLSFMLLAGVL

CLEC4M

51

Q9H2X3
GRMAASLLAVLLLLL

CNDP1

6

Q96KN2
SLLAVLLLLLERGMF

CNDP1

11

Q96KN2
MFSFVDLRLLLLLAA

COL1A1

1

P02452
ALLALLVSLRDLIEM

SLC7A14

396

Q8TBB6
MALQRTHSLLLLLLL

RNASE4

1

P34096
MLSLLPARIIRLLEF

TTC39B

311

Q5VTQ0
RAALMVFLLLTTLLL

PROM2

151

Q8N271
LLLIVRLAVLMAVTL

SLC38A2

371

Q96QD8
LIAILLFSVGMILRL

TRPM3

971

Q9HCF6
LLVLLLVILARMFQT

SUSD4

331

Q5VX71
MLLLALLLLLRLATL

TMEM115

171

Q12893
FMLLILERSTRSILF

SERPINA7

391

P05543
AAMLRLLLLVAFALV

TMEM53

166

Q6P2H8
FVLSLLTIMVLLIRA

TMEM116

96

Q8NCL8
AFAIIATLLMLNLLI

TRPV6

601

Q9H1D0
MLEGALTFLVILLSL

UBR3

761

Q6ZT12
RMSLLILVSIFLSAA

TMEM41B

51

Q5BJD5
LFILLSLALISDAMV

TMIGD3

61

P0DMS9
MLLLLSDQLLLTALR

ZNF34

1

Q8IZ26
LALDISMLRLFETFL

XKR8

126

Q9H6D3
LLLVVMLLLTARLTL

THPO

6

P40225
EIFLVSILLLTLMLV

NALCN

1016

Q8IZF0