Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	olfactory receptor activity	OR5P3 OR5B3 OR5M10 OR5M1 OR4D10 OR13C8 OR1S2 OR1F12P OR13G1 OR5AR1 OR9G9 OR8G2P OR52R1 OR4P4 OR2D2	2.14e-09	431	96	15	GO:0004984
GeneOntologyMolecularFunction	G protein-coupled receptor activity	OR5P3 OR5B3 OR5M10 GPR20 OR5M1 OR4D10 OR13C8 OR1S2 OR1F12P OR13G1 OR5AR1 PTH1R OR9G9 GLP2R OR8G2P OR52R1 OR4P4 TAS1R1 OR2D2	3.48e-08	884	96	19	GO:0004930
GeneOntologyMolecularFunction	transmembrane signaling receptor activity	OR5P3 OR5B3 OR5M10 GPR20 GFRAL OR5M1 OR4D10 OR13C8 OR1S2 CLEC1B OR1F12P OR13G1 OR5AR1 PTH1R OR9G9 GLP2R OR8G2P OR52R1 OR4P4 TAS1R1 OR2D2 PLXNB3	3.36e-07	1353	96	22	GO:0004888
GeneOntologyMolecularFunction	odorant binding	OR5P3 OR5B3 OR5M10 OR5M1 OR13G1 OR5AR1 OR8G2P	2.66e-06	127	96	7	GO:0005549
GeneOntologyMolecularFunction	p53 binding	BLM SMARCA4 SETD7 HTT	5.19e-04	77	96	4	GO:0002039
GeneOntologyBiologicalProcess	sensory perception of chemical stimulus	OR5P3 OR5B3 OR5M10 OR5M1 OR4D10 OR13C8 OR1S2 OR1F12P BBS1 OR13G1 OR5AR1 OR9G9 OR8G2P OR52R1 OR4P4 SCNN1A TAS1R1 SCNN1G OR2D2	8.40e-12	547	97	19	GO:0007606
GeneOntologyBiologicalProcess	sensory perception of smell	OR5P3 OR5B3 OR5M10 OR5M1 OR4D10 OR13C8 OR1S2 OR1F12P BBS1 OR13G1 OR5AR1 OR9G9 OR8G2P OR52R1 OR4P4 OR2D2	5.12e-10	465	97	16	GO:0007608
GeneOntologyBiologicalProcess	detection of chemical stimulus involved in sensory perception	OR5P3 OR5B3 OR5M10 OR5M1 OR4D10 OR13C8 OR1S2 OR1F12P OR13G1 OR5AR1 OR9G9 OR8G2P OR52R1 OR4P4 TAS1R1 OR2D2	9.42e-10	485	97	16	GO:0050907
GeneOntologyBiologicalProcess	detection of chemical stimulus involved in sensory perception of smell	OR5P3 OR5B3 OR5M10 OR5M1 OR4D10 OR13C8 OR1S2 OR1F12P OR13G1 OR5AR1 OR9G9 OR8G2P OR52R1 OR4P4 OR2D2	1.66e-09	432	97	15	GO:0050911
GeneOntologyBiologicalProcess	detection of stimulus involved in sensory perception	OR5P3 OR5B3 OR5M10 OR5M1 OR4D10 OR13C8 OR1S2 OR1F12P OR13G1 OR5AR1 OR9G9 OR8G2P WDR47 OR52R1 OR4P4 TAS1R1 OR2D2	1.68e-09	582	97	17	GO:0050906
GeneOntologyBiologicalProcess	detection of chemical stimulus	OR5P3 OR5B3 OR5M10 OR5M1 OR4D10 OR13C8 OR1S2 OR1F12P OR13G1 OR5AR1 OR9G9 OR8G2P OR52R1 OR4P4 TAS1R1 OR2D2	2.86e-09	524	97	16	GO:0009593
GeneOntologyBiologicalProcess	detection of stimulus	OR5P3 OR5B3 OR5M10 OR5M1 OR4D10 OR13C8 OR1S2 OR1F12P OR13G1 OR5AR1 OR9G9 OR8G2P WDR47 OR52R1 OR4P4 TAS1R1 OR2D2	4.07e-08	722	97	17	GO:0051606
GeneOntologyBiologicalProcess	sensory perception	OR5P3 OR5B3 OR5M10 OR5M1 OR4D10 OR13C8 OR1S2 OR1F12P BBS1 OR13G1 OR5AR1 OR9G9 OR8G2P WDR47 OR52R1 OR4P4 SCNN1A TAS1R1 SCNN1G OR2D2	1.04e-07	1072	97	20	GO:0007600
GeneOntologyBiologicalProcess	G protein-coupled receptor signaling pathway	OR5P3 OR5B3 OR5M10 GPR20 OR5M1 OR4D10 OR13C8 OR1S2 OR1F12P OR13G1 OR5AR1 PTH1R OR9G9 GLP2R OR8G2P OR52R1 OR4P4 TAS1R1 OR2D2 OXSR1 HTT	1.62e-06	1395	97	21	GO:0007186
GeneOntologyBiologicalProcess	sensory perception of salty taste	SCNN1A SCNN1G	1.31e-04	4	97	2	GO:0050914
HumanPheno	Abnormality of the pharynx	FOXN1 EXOSC9 DOCK8 BLM SCNN1A SMARCA2 SCNN1G SMARCA4 PRKCD HYDIN HTT	1.31e-05	320	38	11	HP:0000600
HumanPheno	Bronchitis	BLM SCNN1A SMARCA2 SCNN1G PRKCD HYDIN	1.46e-05	74	38	6	HP:0012387
HumanPheno	Recurrent upper respiratory tract infections	FOXN1 DOCK8 BLM SCNN1A SMARCA2 SCNN1G SMARCA4 PRKCD HYDIN	4.38e-05	237	38	9	HP:0002788
HumanPheno	Pneumonia	FOXN1 DOCK8 ARPC1B BLM SCNN1A SMARCA2 SCNN1G SMARCA4 PRKCD HYDIN	6.34e-05	311	38	10	HP:0002090
HumanPheno	Abnormal nasopharynx morphology	FOXN1 DOCK8 BLM SCNN1A SMARCA2 SCNN1G SMARCA4 PRKCD HYDIN	6.45e-05	249	38	9	HP:0001739
HumanPheno	Abnormal pharynx morphology	FOXN1 DOCK8 BLM SCNN1A SMARCA2 SCNN1G SMARCA4 PRKCD HYDIN	9.04e-05	260	38	9	HP:0033151
MousePheno	abnormal proerythroblast morphology	FLI1 BLM FANCD2 SAMD9L UNC93B1	2.34e-05	74	65	5	MP:0002416
Domain	Olfact_rcpt	OR5P3 OR5B3 OR5M10 OR5M1 OR4D10 OR13C8 OR1S2 OR1F12P OR13G1 OR5AR1 OR9G9 OR8G2P OR52R1 OR4P4 OR2D2	1.28e-09	393	95	15	IPR000725
Domain	7tm_1	OR5P3 OR5B3 OR5M10 GPR20 OR5M1 OR4D10 OR13C8 OR1S2 OR1F12P OR13G1 OR5AR1 OR9G9 OR8G2P OR52R1 OR4P4 OR2D2	2.86e-07	677	95	16	PF00001
Domain	G_PROTEIN_RECEP_F1_1	OR5P3 OR5B3 OR5M10 GPR20 OR5M1 OR4D10 OR13C8 OR1S2 OR1F12P OR13G1 OR5AR1 OR9G9 OR8G2P OR52R1 OR4P4 OR2D2	3.34e-07	685	95	16	PS00237
Domain	G_PROTEIN_RECEP_F1_2	OR5P3 OR5B3 OR5M10 GPR20 OR5M1 OR4D10 OR13C8 OR1S2 OR1F12P OR13G1 OR5AR1 OR9G9 OR8G2P OR52R1 OR4P4 OR2D2	3.76e-07	691	95	16	PS50262
Domain	GPCR_Rhodpsn	OR5P3 OR5B3 OR5M10 GPR20 OR5M1 OR4D10 OR13C8 OR1S2 OR1F12P OR13G1 OR5AR1 OR9G9 OR8G2P OR52R1 OR4P4 OR2D2	3.83e-07	692	95	16	IPR000276
Domain	GPCR_Rhodpsn_7TM	OR5P3 OR5B3 OR5M10 GPR20 OR5M1 OR4D10 OR13C8 OR1S2 OR13G1 OR5AR1 OR9G9 OR8G2P OR52R1 OR4P4 OR2D2	1.38e-06	670	95	15	IPR017452
Domain	SnAC	SMARCA2 SMARCA4	2.56e-05	2	95	2	SM01314
Domain	Gln-Leu-Gln_QLQ	SMARCA2 SMARCA4	2.56e-05	2	95	2	IPR014978
Domain	SnAC	SMARCA2 SMARCA4	2.56e-05	2	95	2	IPR029295
Domain	SnAC	SMARCA2 SMARCA4	2.56e-05	2	95	2	PF14619
Domain	QLQ	SMARCA2 SMARCA4	2.56e-05	2	95	2	SM00951
Domain	QLQ	SMARCA2 SMARCA4	2.56e-05	2	95	2	PS51666
Domain	QLQ	SMARCA2 SMARCA4	2.56e-05	2	95	2	PF08880
Domain	HSA	SMARCA2 SMARCA4	1.53e-04	4	95	2	SM00573
Domain	HSA	SMARCA2 SMARCA4	1.53e-04	4	95	2	PS51204
Domain	HSA_dom	SMARCA2 SMARCA4	1.53e-04	4	95	2	IPR014012
Domain	HSA	SMARCA2 SMARCA4	1.53e-04	4	95	2	PF07529
Domain	BRK	SMARCA2 SMARCA4	3.79e-04	6	95	2	SM00592
Domain	BRK_domain	SMARCA2 SMARCA4	3.79e-04	6	95	2	IPR006576
Domain	BRK	SMARCA2 SMARCA4	3.79e-04	6	95	2	PF07533
Domain	ZnF_U1	ZNF407 ZFHX4 ZFHX3	4.23e-04	29	95	3	SM00451
Domain	Znf_U1	ZNF407 ZFHX4 ZFHX3	4.23e-04	29	95	3	IPR003604
Domain	ENaC	SCNN1A SCNN1G	5.29e-04	7	95	2	IPR004724
Domain	Na+channel_ASC_CS	SCNN1A SCNN1G	7.03e-04	8	95	2	IPR020903
Domain	ASC	SCNN1A SCNN1G	9.00e-04	9	95	2	PF00858
Domain	ASC	SCNN1A SCNN1G	9.00e-04	9	95	2	PS01206
Domain	Na+channel_ASC	SCNN1A SCNN1G	9.00e-04	9	95	2	IPR001873
Domain	Helicase_C	DDX17 BLM SMARCA2 SMARCA4	2.17e-03	107	95	4	PF00271
Domain	HELICc	DDX17 BLM SMARCA2 SMARCA4	2.17e-03	107	95	4	SM00490
Domain	Helicase_C	DDX17 BLM SMARCA2 SMARCA4	2.25e-03	108	95	4	IPR001650
Domain	HELICASE_CTER	DDX17 BLM SMARCA2 SMARCA4	2.32e-03	109	95	4	PS51194
Domain	HELICASE_ATP_BIND_1	DDX17 BLM SMARCA2 SMARCA4	2.32e-03	109	95	4	PS51192
Domain	DEXDc	DDX17 BLM SMARCA2 SMARCA4	2.32e-03	109	95	4	SM00487
Domain	Helicase_ATP-bd	DDX17 BLM SMARCA2 SMARCA4	2.40e-03	110	95	4	IPR014001
Domain	ARM-like	DOCK8 MROH5 HUWE1 PPP4R3B CSE1L HTT	2.56e-03	270	95	6	IPR011989
Domain	Apc4_WD40_dom	COPA WDR47	4.58e-03	20	95	2	IPR024977
Domain	ANAPC4_WD40	COPA WDR47	4.58e-03	20	95	2	PF12894
Pathway	REACTOME_SENSORY_PERCEPTION	OR5P3 OR5B3 OR5M10 OR5M1 OR4D10 OR13C8 OR1S2 OR1F12P OR13G1 OR5AR1 OR9G9 OR52R1 OR4P4 SCNN1A TAS1R1 SCNN1G OR2D2	3.41e-08	636	76	17	M41834
Pathway	REACTOME_OLFACTORY_SIGNALING_PATHWAY	OR5P3 OR5B3 OR5M10 OR5M1 OR4D10 OR13C8 OR1S2 OR1F12P OR13G1 OR5AR1 OR9G9 OR52R1 OR4P4 OR2D2	4.08e-08	417	76	14	M4072
Pathway	KEGG_OLFACTORY_TRANSDUCTION	OR5P3 OR5B3 OR5M10 OR5M1 OR4D10 OR13C8 OR1S2 OR13G1 OR5AR1 OR8G2P OR52R1 OR4P4 OR2D2	1.39e-07	389	76	13	M14091
Pathway	PID_P53_REGULATION_PATHWAY	HUWE1 CSE1L PRKCD SETD7	2.84e-04	59	76	4	M261
Pubmed	Different evolutionary processes shaped the mouse and human olfactory receptor gene families.	OR5P3 OR5B3 OR5M10 OR5M1 OR4D10 OR13C8 OR1S2 OR1F12P OR13G1 OR5AR1 OR8G2P OR52R1 OR4P4 OR2D2	1.00e-12	340	99	14	11875048
Pubmed	The olfactory receptor gene superfamily of the mouse.	OR5P3 OR5B3 OR5M10 OR5M1 OR4D10 OR13C8 OR1S2 OR1F12P OR13G1 OR5AR1 OR8G2P OR52R1 OR4P4 OR2D2	1.00e-12	340	99	14	11802173
Pubmed	A unified nomenclature for vertebrate olfactory receptors.	OR5P3 OR5B3 OR5M10 OR5M1 OR4D10 OR13C8 OR1S2 OR1F12P OR13G1 OR5AR1 OR8G2P OR52R1 OR4P4 OR2D2	1.13e-12	343	99	14	32295537
Pubmed	Odorant receptor expressed sequence tags demonstrate olfactory expression of over 400 genes, extensive alternate splicing and unequal expression levels.	OR5P3 OR5B3 OR5M10 OR5M1 OR4D10 OR13C8 OR1S2 OR1F12P OR13G1 OR5AR1 OR8G2P OR52R1 OR4P4 OR2D2	1.27e-12	346	99	14	14611657
Pubmed	The human olfactory receptor gene family.	OR5P3 OR5B3 OR5M10 OR5M1 OR4D10 OR13C8 OR1S2 OR1F12P OR13G1 OR5AR1 OR8G2P OR52R1 OR2D2	4.95e-09	541	99	13	14983052
Pubmed	Direct interaction between hnRNP-M and CDC5L/PLRG1 proteins affects alternative splice site choice.	DDX17 COPA DOCK8 HUWE1 BLM FANCD2 CSE1L SMARCA2 SMARCA4 OXSR1 CNOT1	8.75e-07	582	99	11	20467437
Pubmed	FAN1 controls mismatch repair complex assembly via MLH1 retention to stabilize CAG repeat expansion in Huntington's disease.	MSH3 FANCD2 HTT	1.24e-06	8	99	3	34469738
Pubmed	Identification of the hypoxia-inducible factor 2α nuclear interactome in melanoma cells reveals master proteins involved in melanoma development.	CNOT10 SMARCA2 SMARCA4 MED23 CNOT1	1.31e-06	66	99	5	23275444
Pubmed	Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.	DDX17 COPA CGAS MSH3 HUWE1 ARPC1B WDR47 BLM RLF SMG8 LRPPRC NOP14 CSE1L SMARCA2 SMARCA4 PRKCD	1.36e-06	1353	99	16	29467282
Pubmed	Promoting anti-tumor immunity by targeting TMUB1 to modulate PD-L1 polyubiquitination and glycosylation.	COPA SPAG9 HUWE1 LRPPRC CSE1L	2.03e-06	72	99	5	36376293
Pubmed	Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.	COPA SPAG9 HUWE1 THOC2 BLM LRPPRC NOP14 CSE1L SMARCA2 SMARCA4 CNOT1	2.66e-06	653	99	11	22586326
Pubmed	DEFOG: a practical scheme for deciphering families of genes.	OR5P3 OR5M1 OR4D10 OR13C8 OR1S2 OR4P4 OR2D2	3.25e-06	219	99	7	12213199
Pubmed	KAP1 facilitates reinstatement of heterochromatin after DNA replication.	EXOSC9 DDX17 COPA MSH3 HUWE1 ARPC1B FANCD2 SMARCA2 SMARCA4 OXSR1 CNOT1	5.43e-06	704	99	11	29955894
Pubmed	Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes.	FOXN1 COPA SPAG9 MSH3 FNBP1L HUWE1 WDR47 BLM NOP14 ZFHX4 SMARCA4 SETD7	6.03e-06	857	99	12	25609649
Pubmed	Epithelial sodium channel genes Scnn1b and Scnn1g are closely linked on distal mouse chromosome 7.	ZP2 SCNN1A SCNN1G	6.27e-06	13	99	3	8575777
Pubmed	Interaction network of human early embryonic transcription factors.	FLI1 MSH3 RLF ZNF462 ZFHX4 SMARCA2 SMARCA4 ZFHX3	7.66e-06	351	99	8	38297188
Pubmed	The hbrm and BRG-1 proteins, components of the human SNF/SWI complex, are phosphorylated and excluded from the condensed chromosomes during mitosis.	SMARCA2 SMARCA4	8.02e-06	2	99	2	8670841
Pubmed	alpha Pix enhances mutant huntingtin aggregation.	ARHGEF6 HTT	8.02e-06	2	99	2	19969308
Pubmed	Lung cancer with loss of BRG1/BRM, shows epithelial mesenchymal transition phenotype and distinct histologic and genetic features.	SMARCA2 SMARCA4	8.02e-06	2	99	2	23163725
Pubmed	Combined gene dosage requirement for SWI/SNF catalytic subunits during early mammalian development.	SMARCA2 SMARCA4	8.02e-06	2	99	2	23076393
Pubmed	Dose-dependent reduction of somatic expansions but not Htt aggregates by di-valent siRNA-mediated silencing of MSH3 in HdhQ111 mice.	MSH3 HTT	8.02e-06	2	99	2	38267530
Pubmed	Differential preimplantation regulation of two mouse homologues of the yeast SWI2 protein.	SMARCA2 SMARCA4	8.02e-06	2	99	2	9603422
Pubmed	The SWI/SNF chromatin remodeling protein Brg1 is required for vertebrate neurogenesis and mediates transactivation of Ngn and NeuroD.	SMARCA2 SMARCA4	8.02e-06	2	99	2	15576411
Pubmed	BLM and the FANC proteins collaborate in a common pathway in response to stalled replication forks.	BLM FANCD2	8.02e-06	2	99	2	15257300
Pubmed	Cyclic GMP-AMP synthase promotes the inflammatory and autophagy responses in Huntington disease.	CGAS HTT	8.02e-06	2	99	2	32581130
Pubmed	SWI/SNF gene variants and glioma risk and outcome.	SMARCA2 SMARCA4	8.02e-06	2	99	2	23276717
Pubmed	Differential Expression of SWI/SNF Chromatin Remodeler Subunits Brahma and Brahma-Related Gene During Drug-Induced Liver Injury and Regeneration in Mouse Model.	SMARCA2 SMARCA4	8.02e-06	2	99	2	27097303
Pubmed	Chromatin remodeling factors and BRM/BRG1 expression as prognostic indicators in non-small cell lung cancer.	SMARCA2 SMARCA4	8.02e-06	2	99	2	15240517
Pubmed	Concomitant loss of SMARCA2 and SMARCA4 expression in small cell carcinoma of the ovary, hypercalcemic type.	SMARCA2 SMARCA4	8.02e-06	2	99	2	26564006
Pubmed	SMARCA4/SMARCA2-deficient Carcinoma of the Esophagus and Gastroesophageal Junction.	SMARCA2 SMARCA4	8.02e-06	2	99	2	33027072
Pubmed	SMARCA4 and SMARCA2 deficiency in non-small cell lung cancer: immunohistochemical survey of 316 consecutive specimens.	SMARCA2 SMARCA4	8.02e-06	2	99	2	28038711
Pubmed	A synthetic lethality-based strategy to treat cancers harboring a genetic deficiency in the chromatin remodeling factor BRG1.	SMARCA2 SMARCA4	8.02e-06	2	99	2	23872584
Pubmed	Proinflammatory stimuli engage Brahma related gene 1 and Brahma in endothelial injury.	SMARCA2 SMARCA4	8.02e-06	2	99	2	23963727
Pubmed	SW13 cells can transition between two distinct subtypes by switching expression of BRG1 and Brm genes at the post-transcriptional level.	SMARCA2 SMARCA4	8.02e-06	2	99	2	12493776
Pubmed	Heterozygous Mutations in SMARCA2 Reprogram the Enhancer Landscape by Global Retargeting of SMARCA4.	SMARCA2 SMARCA4	8.02e-06	2	99	2	31375262
Pubmed	Alterations of the SWI/SNF chromatin remodelling subunit-BRG1 and BRM in hepatocellular carcinoma.	SMARCA2 SMARCA4	8.02e-06	2	99	2	23088494
Pubmed	Aberrant expression of SWI/SNF catalytic subunits BRG1/BRM is associated with tumor development and increased invasiveness in prostate cancers.	SMARCA2 SMARCA4	8.02e-06	2	99	2	17075831
Pubmed	SET7/9-mediated methylation affects oncogenic functions of histone demethylase JMJD2A.	KDM4A SETD7	8.02e-06	2	99	2	37870957
Pubmed	SWI/SNF chromatin remodeling enzyme ATPases promote cell proliferation in normal mammary epithelial cells.	SMARCA2 SMARCA4	8.02e-06	2	99	2	20333683
Pubmed	SWI/SNF Complex-deficient Undifferentiated Carcinoma of the Gastrointestinal Tract: Clinicopathologic Study of 30 Cases With an Emphasis on Variable Morphology, Immune Features, and the Prognostic Significance of Different SMARCA4 and SMARCA2 Subunit Deficiencies.	SMARCA2 SMARCA4	8.02e-06	2	99	2	34812766
Pubmed	Epithelial sodium channels are activated by furin-dependent proteolysis.	SCNN1A SCNN1G	8.02e-06	2	99	2	15007080
Pubmed	Loss of SWI/SNF Chromatin Remodeling Alters NRF2 Signaling in Non-Small Cell Lung Carcinoma.	SMARCA2 SMARCA4	8.02e-06	2	99	2	32855269
Pubmed	Targeting of BRM Sensitizes BRG1-Mutant Lung Cancer Cell Lines to Radiotherapy.	SMARCA2 SMARCA4	8.02e-06	2	99	2	30478150
Pubmed	Downregulation of SWI/SNF chromatin remodeling factor subunits modulates cisplatin cytotoxicity.	SMARCA2 SMARCA4	8.02e-06	2	99	2	22721696
Pubmed	Chromatin remodeling complexes interact dynamically with a glucocorticoid receptor-regulated promoter.	SMARCA2 SMARCA4	8.02e-06	2	99	2	18508913
Pubmed	Compensation of BRG-1 function by Brm: insight into the role of the core SWI-SNF subunits in retinoblastoma tumor suppressor signaling.	SMARCA2 SMARCA4	8.02e-06	2	99	2	11719516
Pubmed	Cleavage of endogenous γENaC and elevated abundance of αENaC are associated with increased Na⁺ transport in response to apical fluid volume expansion in human H441 airway epithelial cells.	SCNN1A SCNN1G	8.02e-06	2	99	2	21667229
Pubmed	The mouse ZFH-4 protein contains four homeodomains and twenty-two zinc fingers.	ZFHX4 ZFHX3	8.02e-06	2	99	2	10873665
Pubmed	The SWI/SNF ATPases Are Required for Triple Negative Breast Cancer Cell Proliferation.	SMARCA2 SMARCA4	8.02e-06	2	99	2	25808524
Pubmed	Antagonistic roles for BRM and BRG1 SWI/SNF complexes in differentiation.	SMARCA2 SMARCA4	8.02e-06	2	99	2	19144648
Pubmed	DNA binding drives the association of BRG1/hBRM bromodomains with nucleosomes.	SMARCA2 SMARCA4	8.02e-06	2	99	2	28706277
Pubmed	Epigenome-wide association of myocardial infarction with DNA methylation sites at loci related to cardiovascular disease.	SMARCA4 ZFHX3	8.02e-06	2	99	2	28515798
Pubmed	Associations of epithelial sodium channel genes with blood pressure changes and hypertension incidence: the GenSalt study.	SCNN1A SCNN1G	8.02e-06	2	99	2	24735600
Pubmed	Estrogen regulates the expression and activity of epithelial sodium channel in mouse osteoblasts.	SCNN1A SCNN1G	8.02e-06	2	99	2	21624334
Pubmed	A potential role for interleukin-33 and γ-epithelium sodium channel in the pathogenesis of human malaria associated lung injury.	SCNN1G IL33	8.02e-06	2	99	2	26437894
Pubmed	[Expression of BRG1 and BRM proteins in prostatic cancer].	SMARCA2 SMARCA4	8.02e-06	2	99	2	21092585
Pubmed	High expression of SMARCA4 or SMARCA2 is frequently associated with an opposite prognosis in cancer.	SMARCA2 SMARCA4	8.02e-06	2	99	2	29391527
Pubmed	Expression of SMARCA2 and SMARCA4 in gastric adenocarcinoma and construction of a nomogram prognostic model.	SMARCA2 SMARCA4	8.02e-06	2	99	2	37634210
Pubmed	SWI/SNF Complex-deficient Undifferentiated/Rhabdoid Carcinomas of the Gastrointestinal Tract: A Series of 13 Cases Highlighting Mutually Exclusive Loss of SMARCA4 and SMARCA2 and Frequent Co-inactivation of SMARCB1 and SMARCA2.	SMARCA2 SMARCA4	8.02e-06	2	99	2	26551623
Pubmed	FANCD2 limits BLM-dependent telomere instability in the alternative lengthening of telomeres pathway.	BLM FANCD2	8.02e-06	2	99	2	27427384
Pubmed	SWI/SNF deficiency results in aberrant chromatin organization, mitotic failure, and diminished proliferative capacity.	SMARCA2 SMARCA4	8.02e-06	2	99	2	19458193
Pubmed	Two human homologues of Saccharomyces cerevisiae SWI2/SNF2 and Drosophila brahma are transcriptional coactivators cooperating with the estrogen receptor and the retinoic acid receptor.	SMARCA2 SMARCA4	8.02e-06	2	99	2	8208605
Pubmed	Sodium and epithelial sodium channels participate in the regulation of the capacitation-associated hyperpolarization in mouse sperm.	SCNN1A SCNN1G	8.02e-06	2	99	2	16407190
Pubmed	The Bromodomains of the mammalian SWI/SNF (mSWI/SNF) ATPases Brahma (BRM) and Brahma Related Gene 1 (BRG1) promote chromatin interaction and are critical for skeletal muscle differentiation.	SMARCA2 SMARCA4	8.02e-06	2	99	2	34289068
Pubmed	SMARCA4/2 loss inhibits chemotherapy-induced apoptosis by restricting IP3R3-mediated Ca2+ flux to mitochondria.	SMARCA2 SMARCA4	8.02e-06	2	99	2	34518526
Pubmed	SMARCA family of genes.	SMARCA2 SMARCA4	8.02e-06	2	99	2	32312722
Pubmed	Dual loss of the SWI/SNF complex ATPases SMARCA4/BRG1 and SMARCA2/BRM is highly sensitive and specific for small cell carcinoma of the ovary, hypercalcaemic type.	SMARCA2 SMARCA4	8.02e-06	2	99	2	26356327
Pubmed	Loss of BRG1/BRM in human lung cancer cell lines and primary lung cancers: correlation with poor prognosis.	SMARCA2 SMARCA4	8.02e-06	2	99	2	12566296
Pubmed	A Brg1 null mutation in the mouse reveals functional differences among mammalian SWI/SNF complexes.	SMARCA2 SMARCA4	8.02e-06	2	99	2	11163203
Pubmed	Transcriptional specificity of human SWI/SNF BRG1 and BRM chromatin remodeling complexes.	SMARCA2 SMARCA4	8.02e-06	2	99	2	12620226
Pubmed	SMARCA2-deficiency confers sensitivity to targeted inhibition of SMARCA4 in esophageal squamous cell carcinoma cell lines.	SMARCA2 SMARCA4	8.02e-06	2	99	2	31406271
Pubmed	BRG1 and BRM SWI/SNF ATPases redundantly maintain cardiomyocyte homeostasis by regulating cardiomyocyte mitophagy and mitochondrial dynamics in vivo.	SMARCA2 SMARCA4	8.02e-06	2	99	2	27039070
Pubmed	Partial Inactivation of the Chromatin Remodelers SMARCA2 and SMARCA4 in Virus-Infected Cells by Caspase-Mediated Cleavage.	SMARCA2 SMARCA4	8.02e-06	2	99	2	29848589
Pubmed	Co-regulation of transcription by BRG1 and BRM, two mutually exclusive SWI/SNF ATPase subunits.	SMARCA2 SMARCA4	8.02e-06	2	99	2	29273066
Pubmed	NuRD subunit CHD4 regulates super-enhancer accessibility in rhabdomyosarcoma and represents a general tumor dependency.	ZNF462 ZFHX4 SMARCA2 SMARCA4 ZFHX3	1.18e-05	103	99	5	32744500
Pubmed	Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.	EXOSC9 DDX17 COPA MSH3 HUWE1 THOC2 FANCD2 LRPPRC CSE1L STARD9 SMARCA4 PRKCD EMC2 MED23 CNOT1	1.21e-05	1425	99	15	30948266
Pubmed	MECP2 directly interacts with RNA polymerase II to modulate transcription in human neurons.	DDX17 COPA THOC2 BLM ZNF462 LRPPRC NOP14 CSE1L SMARCA4 PPIL2 MED23 CNOT1 ARHGEF6	1.24e-05	1082	99	13	38697112
Pubmed	Human transcription factor protein interaction networks.	FLI1 COPA CNOT10 SPAG9 BLM RLF ZNF462 NOP14 CSE1L ZFHX4 SMARCA2 SMARCA4 PPIL2 ZFHX3 CNOT1	1.26e-05	1429	99	15	35140242
Pubmed	Large-scale characterization of HeLa cell nuclear phosphoproteins.	COPA SPAG9 HUWE1 THOC2 BLM FANCD2 SMARCA2 SMARCA4 PRKCD OXSR1 ARHGEF6	1.32e-05	774	99	11	15302935
Pubmed	PRISMA and BioID disclose a motifs-based interactome of the intrinsically disordered transcription factor C/EBPα.	FLI1 DDX17 DOCK8 THOC2 ARPC1B RLF PPP4R3B NOP14 SMARCA2 SMARCA4 PPIL2 MED23 CNOT1	1.52e-05	1103	99	13	34189442
Pubmed	Mapping the Ku Interactome Using Proximity-Dependent Biotin Identification in Human Cells.	EXOSC9 DDX17 THOC2 BLM SMARCA4 PPIL2 ZFHX3	1.72e-05	283	99	7	30585729
Pubmed	Common variants in epithelial sodium channel genes contribute to salt sensitivity of blood pressure: The GenSalt study.	SCNN1A SCNN1G	2.40e-05	3	99	2	21562341
Pubmed	Selective Killing of SMARCA2- and SMARCA4-deficient Small Cell Carcinoma of the Ovary, Hypercalcemic Type Cells by Inhibition of EZH2: In Vitro and In Vivo Preclinical Models.	SMARCA2 SMARCA4	2.40e-05	3	99	2	28292935
Pubmed	Inhibition of lung fluid clearance and epithelial Na+ channels by chlorine, hypochlorous acid, and chloramines.	SCNN1A SCNN1G	2.40e-05	3	99	2	20106988
Pubmed	Clinicopathological and prognostic significance of SWI/SNF complex subunits in undifferentiated gastric carcinoma.	SMARCA2 SMARCA4	2.40e-05	3	99	2	36464671
Pubmed	Phosphorylation of Fli1 at threonine 312 by protein kinase C delta promotes its interaction with p300/CREB-binding protein-associated factor and subsequent acetylation in response to transforming growth factor beta.	FLI1 PRKCD	2.40e-05	3	99	2	19158279
Pubmed	Functional and molecular expression of epithelial sodium channels in cultured human endolymphatic sac epithelial cells.	SCNN1A SCNN1G	2.40e-05	3	99	2	19300301
Pubmed	Interactions between intersubunit transmembrane domains regulate the chaperone-dependent degradation of an oligomeric membrane protein.	SCNN1A SCNN1G	2.40e-05	3	99	2	27903760
Pubmed	DNA damage sensitivity of SWI/SNF-deficient cells depends on TFIIH subunit p62/GTF2H1.	SMARCA2 SMARCA4	2.40e-05	3	99	2	30287812
Pubmed	Expression and distribution of epithelial sodium channel in nasal polyp and nasal mucosa.	SCNN1A SCNN1G	2.40e-05	3	99	2	25559464
Pubmed	Functional role of extracellular loop cysteine residues of the epithelial Na+ channel in Na+ self-inhibition.	SCNN1A SCNN1G	2.40e-05	3	99	2	17522058
Pubmed	BRCA1/FANCD2/BRG1-Driven DNA Repair Stabilizes the Differentiation State of Human Mammary Epithelial Cells.	FANCD2 SMARCA4	2.40e-05	3	99	2	27373334
Pubmed	Insulin ameliorates pulmonary edema through the upregulation of epithelial sodium channel via the PI3K/SGK1 pathway in mice with lipopolysaccharide‑induced lung injury.	SCNN1A SCNN1G	2.40e-05	3	99	2	30628684
Pubmed	Epithelial sodium channels (ENaC) are uniformly distributed on motile cilia in the oviduct and the respiratory airways.	SCNN1A SCNN1G	2.40e-05	3	99	2	22207244
Pubmed	Fluorescence resonance energy transfer analysis of subunit stoichiometry of the epithelial Na+ channel.	SCNN1A SCNN1G	2.40e-05	3	99	2	15096495
Pubmed	Cloning and functional expression of the mouse epithelial sodium channel.	SCNN1A SCNN1G	2.40e-05	3	99	2	10409305
Pubmed	Regulation of ENaC-mediated sodium transport by glucocorticoids in Reissner's membrane epithelium.	SCNN1A SCNN1G	2.40e-05	3	99	2	19144862
Pubmed	Epithelial Na+ channels are fully activated by furin- and prostasin-dependent release of an inhibitory peptide from the gamma-subunit.	SCNN1A SCNN1G	2.40e-05	3	99	2	17199078
Pubmed	N-linked glycans are required on epithelial Na+ channel subunits for maturation and surface expression.	SCNN1A SCNN1G	2.40e-05	3	99	2	29187368
Pubmed	Regulation of the epithelial Na+ channel by cytosolic ATP.	SCNN1A SCNN1G	2.40e-05	3	99	2	12876281
Interaction	CENPA interactions	DDX17 MSH3 THOC2 BLM RLF ZNF462 LRPPRC NOP14 SMARCA2 PPIL2	5.75e-06	377	88	10	int:CENPA
Interaction	EPAS1 interactions	CNOT10 BBS1 SMARCA2 SMARCA4 ZFHX3 MED23 CNOT1	1.08e-05	173	88	7	int:EPAS1
Interaction	TEAD1 interactions	CGAS ARPC1B RLF ZNF462 ZFHX4 SMARCA2 ZFHX3	1.20e-05	176	88	7	int:TEAD1
Interaction	RCN2 interactions	HUWE1 FANCD2 ZNF462 LRPPRC SMARCA2 UNC93B1 EMC2 HTT	3.25e-05	282	88	8	int:RCN2
Interaction	GSC interactions	FLI1 ZNF462 ZFHX4 ZFHX3 DSG4	3.95e-05	87	88	5	int:GSC
Interaction	PML interactions	EXOSC9 SPAG9 FNBP1L THOC2 BLM FANCD2 LRPPRC CSE1L SMARCA4 PPIL2 OXSR1 MED23 PADI3 HTT	4.97e-05	933	88	14	int:PML
Interaction	ERG interactions	FLI1 EXOSC9 MSH3 HUWE1 ZFHX4 SMARCA2 SMARCA4	5.49e-05	223	88	7	int:ERG
Interaction	PPP6C interactions	COPA CGAS HUWE1 LRPPRC CSE1L UNC93B1 HTT	6.31e-05	228	88	7	int:PPP6C
Interaction	KLF4 interactions	HUWE1 LRPPRC SMARCA2 SMARCA4 PRKCD SETD7	7.22e-05	160	88	6	int:KLF4
Interaction	CDC5L interactions	DDX17 COPA DOCK8 HUWE1 THOC2 FANCD2 NOP14 CSE1L SMARCA2 SMARCA4 PPIL2 OXSR1 CNOT1	8.32e-05	855	88	13	int:CDC5L
Interaction	NANOS1 interactions	CNOT10 CNOT1 KLHDC8B	8.69e-05	20	88	3	int:NANOS1
Cytoband	11q12.1	OR5B3 OR5M10 OR5M1 OR4D10 OR1S2 OR5AR1 OR4P4	6.50e-08	161	99	7	11q12.1
Cytoband	16p12	ZP2 RRN3 SCNN1G	3.48e-06	14	99	3	16p12
Cytoband	Ensembl 112 genes in cytogenetic band chr11q12	OR5B3 OR5M10 OR5M1 OR4D10 OR1S2 OR5AR1	1.07e-04	345	99	6	chr11q12
Cytoband	11p15.4	OR5P3 OR52R1 GVINP1 OR2D2	9.52e-04	200	99	4	11p15.4
Cytoband	Ensembl 112 genes in cytogenetic band chr9p24	DOCK8 SMARCA2 IL33	1.55e-03	105	99	3	chr9p24
Cytoband	8q24.3	GPR20 MROH5 NRBP2	1.92e-03	113	99	3	8q24.3
Cytoband	15q26.3	LYSMD4 PCSK6	3.57e-03	41	99	2	15q26.3
GeneFamily	Olfactory receptors, family 5	OR5P3 OR5B3 OR5M10 OR5M1 OR5AR1	8.38e-05	112	72	5	152
GeneFamily	Sodium channels epithelial	SCNN1A SCNN1G	9.34e-05	4	72	2	185
GeneFamily	CCR4-NOT transcription complex	CNOT10 CNOT1	8.40e-04	11	72	2	1023
GeneFamily	Zinc fingers C2H2-type\|ZF class homeoboxes and pseudogenes	ZFHX4 ZFHX3	1.59e-03	15	72	2	529
ToppCell	facs-Brain_Non-Myeloid-Cerebellum-24m-Mesenchymal-brain_pericyte\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYOM1 TAS1R1 ZFHX3 SLC38A11 HYDIN ARHGEF6	2.19e-06	173	97	6	2415b6ff49f334da570577d4e93484d024a3dbd5
ToppCell	facs-Brain_Non-Myeloid-Cerebellum-24m-Mesenchymal-Pericyte\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYOM1 TAS1R1 ZFHX3 SLC38A11 HYDIN ARHGEF6	2.19e-06	173	97	6	2acd0693a2dfe04e3c1b2125ea63efe92d13150b
ToppCell	facs-Brain_Non-Myeloid-Striatum_-18m-Mesenchymal-Pericyte\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GPR20 MYOM1 CHIT1 PTH1R ZFHX3 SLC38A11	3.23e-06	185	97	6	5f5df92b328be396941b5812d00454b5ff927d30
ToppCell	facs-Brain_Non-Myeloid-Striatum_-18m-Mesenchymal-brain_pericyte\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GPR20 MYOM1 CHIT1 PTH1R ZFHX3 SLC38A11	3.23e-06	185	97	6	98547c1b1828b76da810ed86082182afaaacdb3f
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW16-Mesenchymal\|GW16 / Sample Type, Dataset, Time_group, and Cell type.	FLI1 DOCK8 TBC1D8B ARPC1B PRKCD UNC93B1	5.05e-06	200	97	6	fe22f7c97f4e37dfa7881d0f1d9245c1237d873b
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW16-Mesenchymal-BMP_responsible_cell\|GW16 / Sample Type, Dataset, Time_group, and Cell type.	FLI1 DOCK8 TBC1D8B ARPC1B PRKCD UNC93B1	5.05e-06	200	97	6	26251ed8c7fa7e87973d6f59bd398c88ad025395
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-TAM-MG-TAM-MG_pro-infl_I-Z\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	TBC1D8B SAMD9L PRKCD ZFHX3 UNC93B1	1.65e-05	145	97	5	9743d68ba8bfef56fd9a979ab357c0e287eb5ae2
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-TAM-MG-TAM-MG_pro-infl_II-Z\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	NPIPB4 TBC1D8B ZNF526 SAMD9L UNC93B1	1.94e-05	150	97	5	6c39e73a0b05d4b26589f333ce13924e3d373b8d
ToppCell	Immune-mast_cell\|World / Lineage, Cell type, age group and donor	FLI1 CLEC1B OR13G1 SLC38A11 ARHGEF6	3.74e-05	172	97	5	6e8e0aac5a20dbc789bf8c6916833bb8709a411a
ToppCell	facs-Heart-RA-24m-Mesenchymal-smooth_muscle_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GPR20 MYOM1 BLM SLC38A11 KLHDC8B	4.52e-05	179	97	5	d76a05f1fee7f2f7b7b7994d3622e96f02b49432
ToppCell	facs-Heart-RA-24m-Mesenchymal-smooth_muscle_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GPR20 MYOM1 BLM SLC38A11 KLHDC8B	4.52e-05	179	97	5	6be47c877250968a916c711ba0787eb7b4c5443d
ToppCell	facs-Brain_Non-Myeloid-Cortex-24m-Mesenchymal\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYOM1 PTH1R ZFHX3 SLC38A11 KLHDC8B	4.89e-05	182	97	5	ffe500d78a89dc6b4d05bab1664e7f30c94fb8d9
ToppCell	Pericytes-Cryobiopsy_01\|World / lung cells shred on cell class, cell subclass, sample id	GPR20 MYOM1 PTH1R ITIH1 ZFHX3	4.89e-05	182	97	5	46c213597445b1f4f09dc367f27702d24b201daf
ToppCell	facs-Brain_Non-Myeloid-Cortex-24m-Mesenchymal-Pericyte\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYOM1 PTH1R ZFHX3 SLC38A11 KLHDC8B	5.15e-05	184	97	5	94748f63947db79a6b4540e3090a63689fdd9452
ToppCell	facs-Brain_Non-Myeloid-Cortex-24m-Mesenchymal-brain_pericyte\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYOM1 PTH1R ZFHX3 SLC38A11 KLHDC8B	5.15e-05	184	97	5	819b277ecced7b415e363c7e7ddbc6f3b2d296de
ToppCell	LPS-antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_3\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	GPR20 MYOM1 ZFHX3 SLC38A11 IL33	5.42e-05	186	97	5	4780af76237d7af2abbe2d8d5530cdf53e3ed0b7
ToppCell	LPS-IL1RA+antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_3\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	GPR20 MYOM1 ZFHX3 SLC38A11 IL33	5.42e-05	186	97	5	a95744b8649096bd7cfc3591a02841fa411085b3
ToppCell	droplet-Marrow-nan-3m-Hematologic-megakaryocyte-erythroid_progenitor_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DOCK8 CGAS CHIT1 SAMD9L SCNN1A	5.56e-05	187	97	5	14c239af77116d28d511dea754b6150d20488080
ToppCell	LPS_only-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_3\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	GPR20 MYOM1 ZFHX3 SLC38A11 IL33	5.85e-05	189	97	5	975e7aa3b862a8b07c2ab8426a14f5cc54998aca
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	GPR20 MYOM1 DOCK8 STARD9 SLC38A11	5.85e-05	189	97	5	fac5c291a9a87418bb0878c3d624829bdbf1f428
ToppCell	Somatosensory_Cortex_(S1)-Non-neuronal\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	FLI1 DOCK8 ZFHX4 ZFHX3 PLXNB3	5.85e-05	189	97	5	42ab4cc5fbf8580841f31889446fe4499df1a464
ToppCell	droplet-Kidney-KIDNEY-1m-Epithelial-Stroma____kidney_mesangial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GPR20 MYOM1 ZFHX3 SLC38A11 KLHDC8B	6.15e-05	191	97	5	8597a8af294f24496c317d995f07eb5dcc25c13c
ToppCell	facs-Brain_Non-Myeloid-Hippocampus_-18m-Mesenchymal\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GPR20 MYOM1 ZFHX3 SLC38A11 KLHDC8B	6.15e-05	191	97	5	96ff4cfbdcaec4b8568f9482d732dddd399121d3
ToppCell	facs-Brain_Non-Myeloid-Hippocampus-3m-Mesenchymal-Pericyte\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GPR20 MYOM1 PTH1R ZFHX3 SLC38A11	6.15e-05	191	97	5	cb75e6c36dbe2e091e407d691c063ec7c4fd5f90
ToppCell	facs-Brain_Non-Myeloid-Hippocampus-3m-Mesenchymal-brain_pericyte\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GPR20 MYOM1 PTH1R ZFHX3 SLC38A11	6.15e-05	191	97	5	b2cffea7860dd590b505ee0ebd51aa1978cb5e64
ToppCell	droplet-Kidney-nan-3m-Epithelial-kidney_mesangial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GPR20 MYOM1 ZFHX3 SLC38A11 KLHDC8B	6.30e-05	192	97	5	3617d2bc7e33d981f3ec349e9962d8d4bd822fbd
ToppCell	facs-Brain_Non-Myeloid-Hippocampus-3m-Mesenchymal\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GPR20 MYOM1 PTH1R ZFHX3 SLC38A11	6.30e-05	192	97	5	e5117cdb8af220f60bd1410262078c0306667b4a
ToppCell	droplet-Pancreas-Endocrine-18m-Epithelial-pancreatic_D_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	OLFM3 ZFHX4 SMARCA2 SLC38A11 KLHDC8B	6.46e-05	193	97	5	6995ee29bf403a71247de92a37dfd851be5acf2e
ToppCell	facs-Brain_Non-Myeloid-Cerebellum_-18m-Mesenchymal-brain_pericyte\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GPR20 MYOM1 PTH1R ZFHX3 SLC38A11	6.46e-05	193	97	5	18e11d515147accef9aee26e934b358b445e18e2
ToppCell	severe_COVID-19-Platelet\|World / disease group, cell group and cell class (v2)	CLEC1B FNBP1L PCSK6 NXF3 KLHDC8B	6.46e-05	193	97	5	a598a0665652cc365eb08e413a711c929b80fec7
ToppCell	TCGA-Prostate-Primary_Tumor-Prostate_Adenocarcinoma-Acinar_Adenocarcinoma-6\|TCGA-Prostate / Sample_Type by Project: Shred V9	MSH3 HUWE1 THOC2 LRPPRC MED23	6.46e-05	193	97	5	abd71b2cf667ef2b1c4d88acd0c1dd19a12ff659
ToppCell	facs-Brain_Non-Myeloid-Cerebellum_-18m-Mesenchymal\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GPR20 MYOM1 PTH1R ZFHX3 SLC38A11	6.46e-05	193	97	5	7766f495f2f945802ef9a5b994cd00bb64d0dfe3
ToppCell	PBMC-Severe-Hematopoietic-Platelet-Platelet-plt_5\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	CLEC1B ARPC1B PCSK6 NXF3 KLHDC8B	6.46e-05	193	97	5	a2fb7482e79d6ce5b6b1d9d0c0811d1c58b4d85d
ToppCell	PBMC-Severe-Hematopoietic-Platelet-Platelet-plt_5\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	CLEC1B ARPC1B PCSK6 NXF3 KLHDC8B	6.46e-05	193	97	5	1d724ccb745cfc624119dd6003d53b84b17c94b0
ToppCell	facs-Brain_Non-Myeloid-Cerebellum_-18m-Mesenchymal-Pericyte\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GPR20 MYOM1 PTH1R ZFHX3 SLC38A11	6.46e-05	193	97	5	ce3e8cf30b7b4d5c7a8f3d64c21d81d2c3cab5c1
ToppCell	facs-Brain_Non-Myeloid-Hippocampus_-18m-Mesenchymal-Pericyte\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GPR20 MYOM1 ZFHX3 SLC38A11 KLHDC8B	6.61e-05	194	97	5	3bff2e4eb16719ab7419b2f94c9c6e7302aa6629
ToppCell	droplet-Kidney-KIDNEY-1m-Epithelial-kidney_mesangial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GPR20 MYOM1 ZFHX3 SLC38A11 KLHDC8B	6.61e-05	194	97	5	80be44e9ddd9f6ddd9dff7cba0eb457431204c2d
ToppCell	facs-Brain_Non-Myeloid-Hippocampus_-18m-Mesenchymal-brain_pericyte\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GPR20 MYOM1 ZFHX3 SLC38A11 KLHDC8B	6.61e-05	194	97	5	fdaf61cbe7f77ff5358d150b38adb1fe3778e961
ToppCell	Entopeduncular-Endothelial-MURAL-M1(Rgs5Acta2)-M1_3\|Entopeduncular / BrainAtlas - Mouse McCarroll V32	GPR20 MYOM1 DOCK8 SLC38A11	1.13e-04	114	97	4	108cc5b04cc7c59310eb55dc2c44ae2b8e0b05e4
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-TAM-BDM-TAM-BDM_MHC-Z\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	NPIPB4 TBC1D8B ZNF526 PRKCD	1.33e-04	119	97	4	8eefcf1ace62ad1c90fa5b62ec159c83ec527bf3
Disease	Liddle syndrome (is_implicated_in)	SCNN1A SCNN1G	3.01e-05	3	94	2	DOID:0050477 (is_implicated_in)
Disease	Idiopathic bronchiectasis	SCNN1A SCNN1G	6.00e-05	4	94	2	C0339985
Disease	Liddle Syndrome	SCNN1A SCNN1G	6.00e-05	4	94	2	C0221043
Disease	Idiopathic bronchiectasis	SCNN1A SCNN1G	6.00e-05	4	94	2	cv:C0339985
Disease	Bronchiectasis	SCNN1A SCNN1G	6.00e-05	4	94	2	cv:C0006267
Disease	MENTAL RETARDATION, AUTOSOMAL DOMINANT 12	SMARCA2 SMARCA4	9.98e-05	5	94	2	C3281201
Disease	Lung diseases	DOCK8 PTH1R SCNN1A SCNN1G	1.15e-04	78	94	4	C0024115
Disease	Chronic obstructive pulmonary disease	SCNN1A SCNN1G	1.49e-04	6	94	2	cv:C0024117
Disease	pseudohypoaldosteronism (is_implicated_in)	SCNN1A SCNN1G	2.78e-04	8	94	2	DOID:4479 (is_implicated_in)
Disease	opportunistic bacterial infectious disease (implicated_via_orthology)	SMARCA2 SMARCA4	3.56e-04	9	94	2	DOID:0050340 (implicated_via_orthology)
Disease	Pulmonary Cystic Fibrosis	SCNN1A SCNN1G	3.56e-04	9	94	2	C0392164
Disease	Fibrocystic Disease of Pancreas	SCNN1A SCNN1G	3.56e-04	9	94	2	C1527396
Disease	Pseudohypoaldosteronism	SCNN1A SCNN1G	4.44e-04	10	94	2	C0033805
Disease	Hyperpotassemia and Hypertension, Familial	SCNN1A SCNN1G	4.44e-04	10	94	2	C2713447
Disease	Pseudohypoaldosteronism, Type I	SCNN1A SCNN1G	4.44e-04	10	94	2	C0268436
Disease	Pseudohypoaldosteronism, Type I, Autosomal Recessive	SCNN1A SCNN1G	4.44e-04	10	94	2	C1449843
Disease	Pseudohypoaldosteronism, Type II	SCNN1A SCNN1G	4.44e-04	10	94	2	C1449844
Disease	Pseudohypoaldosteronism, Type I, Autosomal Dominant	SCNN1A SCNN1G	4.44e-04	10	94	2	C1449842
Disease	Cystic Fibrosis	SCNN1A SCNN1G	5.42e-04	11	94	2	C0010674
Disease	Mental Retardation, X-Linked Nonsyndromic	HUWE1 ARHGEF6	7.65e-04	13	94	2	C3501611
Disease	Coffin-Siris syndrome	SMARCA2 SMARCA4	7.65e-04	13	94	2	C0265338
Disease	ischemia (implicated_via_orthology)	SCNN1A SCNN1G	1.32e-03	17	94	2	DOID:326 (implicated_via_orthology)
Disease	triglycerides:total lipids ratio, low density lipoprotein cholesterol measurement	RRN3 PCSK6 SMARCA4 HTT	1.37e-03	150	94	4	EFO_0004611, EFO_0020947
Disease	Hereditary Non-Polyposis Colon Cancer Type 2	MSH3 SMARCA4	1.66e-03	19	94	2	C1333991
Disease	cortical surface area change measurement, age at assessment	SPAG9 PCSK6	1.66e-03	19	94	2	EFO_0008007, EFO_0021503
Disease	Colorectal cancer, hereditary nonpolyposis, type 1	MSH3 SMARCA4	1.66e-03	19	94	2	C2936783
Disease	haptoglobin measurement	ZFHX3 HYDIN	2.03e-03	21	94	2	EFO_0004640
Disease	Bronchiectasis	SCNN1A SCNN1G	2.23e-03	22	94	2	C0006267
Disease	frailty measurement	LRPPRC HTT	2.43e-03	23	94	2	EFO_0009885
Disease	Intellectual Disability	OR5M1 DOCK8 ZNF462 ZNF526 MED23 HTT	3.10e-03	447	94	6	C3714756
Disease	Acute monocytic leukemia	BLM FANCD2	3.10e-03	26	94	2	C0023465
Disease	Hereditary Nonpolyposis Colorectal Neoplasms	MSH3 SMARCA4	3.10e-03	26	94	2	C0009405

Protein segments in the cluster

Peptide	Gene	Start	Entry
YFCRMFSQHIPQTHS	ERVPABLB-1	471	P60509
MYHHFCDFINLYITQ	EOGT	246	Q5NDL2
IHNHQPCSKLFSFYD	ABRAXAS2	56	Q15018
HFKSMYLAYCANHPS	ARHGEF6	326	Q15052
AFTRHPQIMDHCFYQ	ADAM7	96	Q9H2U9
MAYHSFLVEPISCHA	ARPC1B	1	O15143
HIYRVTNFPQAHFIM	GVINP1	601	Q7Z2Y8
RCAFPHVLGYFLNMH	GPR20	121	Q99678
HVLGYFLNMHCSILF	GPR20	126	Q99678
VCYNPMEAHINFSLS	CRAT	576	P43155
YHVKTAFFHVCTQNP	CGAS	436	Q8N884
YHCPVLFTVFTNNTH	PPIL2	101	Q13356
ICYSSNVTPNMLHNF	OR5M10	71	Q6IEU7
SPLLYNVIMSYHHCF	OR8G2P	141	Q6IF36
AMSQCHHPNIVSYYT	OXSR1	66	O95747
FIPYCSMAHAQLCFH	SPAG9	1206	O60271
CTHLIYAFAGMTNHQ	CHIT1	51	Q13231
FVPVEFHYENMHASF	NXF3	141	Q9H4D5
NIYCHLDHNFMTASI	MSH3	271	P20585
SDHCLHTPMYFFLAN	OR1F12P	51	Q8NHA8
VAICFPLHYSTIMNH	OR13G1	121	Q8NGZ3
AAHCFIQHQYLMPEN	NRBP2	316	Q9NSY0
FLHESYCMDTSHQPL	LYSMD4	186	Q5XG99
HFAHFFAPQNLTNMN	ITIH1	276	P19827
HRFKVHNYMSPTFCD	PRKCD	231	Q05655
DFHYSVASQFQMHPT	DSG4	356	Q86SJ6
SIHHMPICVSFAFFQ	EXOSC9	186	Q06265
FYHHQEMNTCVTLCP	PCSK6	771	P29122
HCQAHQFYPSMSQRE	PLXNB3	746	Q9ULL4
SITCTQLIHQPMYFF	OR4P4	46	Q8NGL7
SCLHNPMYFFLSNLS	OR5B3	51	Q8NH48
THLNYMDPICDFLYH	MED23	1286	Q9ULK4
IHFMTYEFLQEHFNP	SLC25A28	241	Q96A46
PHCAVCMIFQTYHQV	KDM4A	666	O75164
QMHSFPLQFTLHCAL	LRPPRC	401	P42704
EFLNFFYNHCMHVLT	PPP4R3B	461	Q5MIZ7
FYNHCMHVLTAPLLT	PPP4R3B	466	Q5MIZ7
LHCTFIDDFTPYHML	PADI3	626	Q9ULW8
VLICNDSHLHTPMYF	OR9G9	46	P0C7N8
YLLSVCGFRFHHQPM	NPIPB4	656	C9JG80
HLYHLCQMFPESASD	NOP14	501	P78316
SSHCNPNHLSYFKFV	HUWE1	4096	Q7Z6Z7
MAFDHFVAICHPLNY	OR1S2	131	Q8NGQ3
VDSQLHTPMYFFLCN	OR2D2	51	Q9H210
FCQHQAIPQSYCEHM	OR52R1	171	Q8NGF1
HYCFMAPYTHFTQAL	HTT	1356	P42858
AFFVLHNMHSNCVSF	IL33	216	O95760
NQSFIPAFFQAHMAH	HYDIN	831	Q4G0P3
LHCTRNYIHMNLFAS	GLP2R	206	O95838
HKVVLASCSPYFHAM	KLHL17	106	Q6TDP4
RETHFNNLYSMVHYC	BLM	1016	P54132
CSHEHYLNLNLFFMN	DOCK8	1101	Q8NF50
QFLTFSIEPVHYCMN	FNBP1L	351	Q5T0N5
IFQHMLHRKSCFNYP	GFRAL	306	Q6UXV0
EMAAYFTHSNLQPVH	COPA	1086	P53621
MYPHLFSERCANQHQ	CASC2	6	Q6XLA1
SYMPSYHAHQQKVNF	FLI1	386	Q01543
HNFYSRPHFVNTVEM	KLHDC8B	236	Q8IXV7
LMMTNPHNHLYCQQY	EMC2	181	Q15006
FAFHHANFPQYVMDV	DDX17	171	Q92841
AHYDPMANIHTFSAC	BBS1	26	Q8NFJ9
QANYSHFHHPMYGNC	SCNN1A	291	P37088
NFTLFHHPMHGNCYT	SCNN1G	271	P51170
MSFAFICHHNSFLVY	SLC38A11	171	Q08AI6
DIPFHNQYFHISMLD	OLFM3	431	Q96PB7
TPMCNHLENIHNYFQ	FANCD2	1021	Q9BXW9
SNNFFAHIPMCVFSL	LRRC30	171	A6NM36
FDSHLHTPMYFFLCN	OR13C8	51	Q8NGS7
TISFNHCFTQMFLFH	OR4D10	91	Q8NGI6
GHTICYHPQAVFQML	MROH5	1261	Q6ZUA9
MAHSAYQSNLPHNYT	SMG8	506	Q8ND04
LPTHASCHVQFFMFY	RRN3	356	Q9NYV6
CNHPYMFQHIEESFA	SMARCA2	1016	P51531
DMTQPLNHYFICSSH	PLCD4	291	Q9BRC7
LTCMPYPFDQFHDSH	SAMD9L	161	Q8IVG5
ICYSSNVTPNMLHNF	OR5M1	71	Q8NGP8
QHMYCSSQPPFHQYS	FOXN1	221	O15353
CNHPYMFQHIEESFS	SMARCA4	1046	P51532
NHSFTPNCIYDMFVH	SETD7	296	Q8WTS6
QMAHHFFAYFQCTPS	THNSL2	231	Q86YJ6
MSSSFYLDPQFQPHC	STARD9	1271	Q9P2P6
TDTQLHTPMYFFLCN	OR5AR1	51	Q8NGP9
HTPMYIFLCHLAFVD	OR5P3	56	Q8WZ94
AYFHNGKMHPTFCEN	CLEC1B	196	Q9P126
CIHFAMSKHNLGIFY	CNOT10	301	Q9H9A5
YCQHLASISHFMQFP	CNOT1	971	A5YKK6
MSHSFANFHYPGVQN	WDR47	341	O94967
ATSFPSLQKYMEHHC	ZFHX4	86	Q86UP3
KPHFNHYMFEAICLS	CSE1L	611	P55060
SFACAQLPMIYFLNH	UNC93B1	231	Q9H1C4
VFNMFCYLGPHLSHD	THOC2	431	Q8NI27
CSFNEHGYHLFQAMR	TAS1R1	66	Q7RTX1
QLTMFQHRYSPFQCH	RLF	1161	Q13129
HVCSQGENHYFSMFL	TBC1D8B	221	Q0IIM8
HCTRNYIHMHLFLSF	PTH1R	216	Q03431
SFASPNMHSVLVHYQ	ZNF462	1036	Q96JM2
LASSLFFQHHQFMCS	ZNF526	46	Q8TF50
HNMHFLCTPCNLFFL	ZNF407	611	Q9C0G0
MTFHVPFNATGVTHY	ZP2	216	Q05996
ASFASLQTYMEHHCP	ZFHX3	86	Q15911
MSLPFYQRCHQHYDL	MYOM1	1	P52179