Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	transporter activity	CACNA1D NAT2 CNNM2 GLTP CHRNA9 CACNA2D2 PIEZO1 PEX1 ABCC5 ABCB6 ABCC9 SLC44A4 SLC5A2 SCN4A SLC28A2 SCNN1B CACNA1I TMC5 APOL2 GRAMD1C	4.98e-05	1289	116	20	GO:0005215
GeneOntologyBiologicalProcess	photoreceptor cell development	NRL MYO7A NAGLU NPHP4 OLFM3	5.48e-05	73	115	5	GO:0042461
GeneOntologyBiologicalProcess	mitotic actomyosin contractile ring assembly	IQGAP2 IQGAP3	9.21e-05	3	115	2	GO:1903475
GeneOntologyBiologicalProcess	mitotic actomyosin contractile ring assembly actin filament organization	IQGAP2 IQGAP3	9.21e-05	3	115	2	GO:1903479
GeneOntologyBiologicalProcess	peptidyl-cysteine methylation	RAB3D RAB3B	9.21e-05	3	115	2	GO:0018125
GeneOntologyBiologicalProcess	assembly of actomyosin apparatus involved in mitotic cytokinesis	IQGAP2 IQGAP3	9.21e-05	3	115	2	GO:1902407
GeneOntologyBiologicalProcess	heme transmembrane transport	ABCC5 ABCB6	9.21e-05	3	115	2	GO:0035351
GeneOntologyBiologicalProcess	anatomical structure homeostasis	CYP19A1 SH3GL2 NAGLU RAB3D LRRK1 IDUA NPHP4 SLC28A2 SYK	1.07e-04	334	115	9	GO:0060249
GeneOntologyBiologicalProcess	tissue homeostasis	CYP19A1 SH3GL2 NAGLU RAB3D LRRK1 IDUA NPHP4 SLC28A2 SYK	1.07e-04	334	115	9	GO:0001894
GeneOntologyBiologicalProcess	cortical actin cytoskeleton organization	IQGAP2 FHOD3 IQGAP3 NCKAP1L	1.15e-04	45	115	4	GO:0030866
GeneOntologyBiologicalProcess	sensory organ morphogenesis	CHRNA9 NRL MYO7A NAGLU SLC44A4 OLFM3 PTPRM SDK1 LARGE1	1.31e-04	343	115	9	GO:0090596
GeneOntologyBiologicalProcess	eye morphogenesis	NRL MYO7A NAGLU OLFM3 PTPRM SDK1 LARGE1	1.48e-04	204	115	7	GO:0048592
GeneOntologyBiologicalProcess	retina morphogenesis in camera-type eye	NRL NAGLU PTPRM SDK1 LARGE1	1.49e-04	90	115	5	GO:0060042
GeneOntologyBiologicalProcess	neuron development	CUL4B RELN FN1 NRL MYO7A PPFIA2 SH3GL2 NAGLU SLC44A4 NPHP4 TNFRSF21 DSCAML1 ANOS1 OLFM3 MEGF8 PTPRM LRP1 SAMD14 SDK1 NCKAP1L	1.60e-04	1463	115	20	GO:0048666
GeneOntologyBiologicalProcess	actomyosin contractile ring assembly actin filament organization	IQGAP2 IQGAP3	1.84e-04	4	115	2	GO:2000689
GeneOntologyBiologicalProcess	photoreceptor cell differentiation	NRL MYO7A NAGLU NPHP4 OLFM3	2.01e-04	96	115	5	GO:0046530
GeneOntologyBiologicalProcess	eye photoreceptor cell development	NRL MYO7A NAGLU OLFM3	2.02e-04	52	115	4	GO:0042462
GeneOntologyBiologicalProcess	bone resorption	CYP19A1 RAB3D LRRK1 IDUA SYK	2.33e-04	99	115	5	GO:0045453
GeneOntologyBiologicalProcess	neural retina development	NRL NAGLU PTPRM SDK1 LARGE1	2.67e-04	102	115	5	GO:0003407
GeneOntologyBiologicalProcess	positive regulation of cell adhesion mediated by integrin	PIEZO1 SYK NCKAP1L	2.76e-04	23	115	3	GO:0033630
GeneOntologyBiologicalProcess	cortical cytoskeleton organization	IQGAP2 FHOD3 IQGAP3 NCKAP1L	2.88e-04	57	115	4	GO:0030865
GeneOntologyBiologicalProcess	astrocyte differentiation	CUL4B NAGLU EIF2B5 LRP1 LARGE1	3.06e-04	105	115	5	GO:0048708
GeneOntologyBiologicalProcess	retina layer formation	PTPRM SDK1 LARGE1	3.55e-04	25	115	3	GO:0010842
GeneOntologyCellularComponent	vesicle membrane	TRAF3 CLTCL1 IQGAP2 SH3GL2 SH3GL3 CD109 RAB3D ABCC5 ABCB6 DDOST PIK3R4 MALRD1 SLC28A2 SCNN1B LRP1 CD300LG RMC1 RAB3B DGAT1 NCKAP1L	3.86e-05	1325	116	20	GO:0012506
GeneOntologyCellularComponent	cytoplasmic vesicle membrane	TRAF3 CLTCL1 IQGAP2 SH3GL2 SH3GL3 CD109 RAB3D ABCC5 ABCB6 DDOST PIK3R4 MALRD1 SCNN1B LRP1 CD300LG RMC1 RAB3B DGAT1 NCKAP1L	1.02e-04	1307	116	19	GO:0030659
GeneOntologyCellularComponent	monoatomic ion channel complex	CACNA1D SESTD1 CHRNA9 CACNA2D2 ABCC9 OLFM3 SCN4A SCNN1B CACNA1I	2.62e-04	378	116	9	GO:0034702
GeneOntologyCellularComponent	cation channel complex	CACNA1D SESTD1 CACNA2D2 ABCC9 SCN4A SCNN1B CACNA1I	3.43e-04	235	116	7	GO:0034703
GeneOntologyCellularComponent	apical part of cell	CACNA1D FN1 MYO7A ABCC5 NEDD1 SLC44A4 SLC5A2 SCNN1B LRP1 CD300LG ADGRF5	4.59e-04	592	116	11	GO:0045177
GeneOntologyCellularComponent	sodium channel complex	SCN4A SCNN1B CACNA1I	5.48e-04	29	116	3	GO:0034706
GeneOntologyCellularComponent	transmembrane transporter complex	CACNA1D SESTD1 CHRNA9 CACNA2D2 ABCB6 ABCC9 OLFM3 SCN4A SCNN1B CACNA1I	6.73e-04	523	116	10	GO:1902495
GeneOntologyCellularComponent	calcium channel complex	CACNA1D SESTD1 CACNA2D2 CACNA1I	7.30e-04	73	116	4	GO:0034704
GeneOntologyCellularComponent	ribbon synapse	CACNA1D SH3GL2 NPHP4	7.34e-04	32	116	3	GO:0097470
GeneOntologyCellularComponent	transporter complex	CACNA1D SESTD1 CHRNA9 CACNA2D2 ABCB6 ABCC9 OLFM3 SCN4A SCNN1B CACNA1I	9.87e-04	550	116	10	GO:1990351
Domain	-	DDX31 MYO7A PEX1 RAB3D ABCC5 ABCB6 RNF213 ABCC9 LRRK1 PSTK SMARCA1 SMARCA2 RAB3B FIGNL1 AGAP1	5.34e-05	746	115	15	3.40.50.300
Domain	RasGAP_C	IQGAP2 IQGAP3	1.12e-04	3	115	2	IPR000593
Domain	RasGAP_C	IQGAP2 IQGAP3	1.12e-04	3	115	2	PF03836
Domain	IQ	IQCH IQGAP2 MYO7A SCN4A IQGAP3	1.43e-04	81	115	5	SM00015
Domain	MAM	ZAN MALRD1 PTPRM	1.45e-04	17	115	3	SM00137
Domain	MAM	ZAN MALRD1 PTPRM	1.73e-04	18	115	3	PF00629
Domain	MAM_dom	ZAN MALRD1 PTPRM	1.73e-04	18	115	3	IPR000998
Domain	MAM_2	ZAN MALRD1 PTPRM	1.73e-04	18	115	3	PS50060
Domain	P-loop_NTPase	DDX31 MYO7A PEX1 RAB3D ABCC5 ABCB6 RNF213 ABCC9 LRRK1 PSTK SMARCA1 SMARCA2 RAB3B FIGNL1 AGAP1	2.20e-04	848	115	15	IPR027417
Domain	IQ_motif_EF-hand-BS	IQCH IQGAP2 MYO7A SCN4A IQGAP3	2.35e-04	90	115	5	IPR000048
Domain	AAA	PEX1 ABCC5 ABCB6 RNF213 ABCC9 FIGNL1	2.67e-04	144	115	6	SM00382
Domain	AAA+_ATPase	PEX1 ABCC5 ABCB6 RNF213 ABCC9 FIGNL1	2.67e-04	144	115	6	IPR003593
Domain	IQ	IQCH IQGAP2 MYO7A SCN4A IQGAP3	2.74e-04	93	115	5	PS50096
Domain	ABC_membrane	ABCC5 ABCB6 ABCC9	4.19e-04	24	115	3	PF00664
Domain	fn3	FN1 DSCAML1 TYRO3 ANOS1 PTPRM SDK1	5.01e-04	162	115	6	PF00041
Domain	ABC_TM1F	ABCC5 ABCB6 ABCC9	6.66e-04	28	115	3	PS50929
Domain	ABC1_TM_dom	ABCC5 ABCB6 ABCC9	6.66e-04	28	115	3	IPR011527
Domain	IQ	IQGAP2 MYO7A SCN4A IQGAP3	9.65e-04	71	115	4	PF00612
Domain	FN3	FN1 DSCAML1 TYRO3 ANOS1 PTPRM SDK1	1.00e-03	185	115	6	SM00060
Domain	EGF_1	RELN ZAN FN1 ADAM21 MALRD1 MEGF8 LRP1	1.02e-03	255	115	7	PS00022
Domain	DAD_dom	FHOD3 DAAM1	1.03e-03	8	115	2	IPR014767
Domain	DAD	FHOD3 DAAM1	1.03e-03	8	115	2	PS51231
Domain	EGF-like_CS	RELN ZAN FN1 ADAM21 MALRD1 MEGF8 LRP1	1.17e-03	261	115	7	IPR013032
Domain	FN3	FN1 DSCAML1 TYRO3 ANOS1 PTPRM SDK1	1.46e-03	199	115	6	PS50853
Domain	Glyco_transf_8	LARGE2 LARGE1	1.64e-03	10	115	2	PF01501
Domain	VDCCAlpha1	CACNA1D CACNA1I	1.64e-03	10	115	2	IPR002077
Domain	Glyco_trans_8	LARGE2 LARGE1	1.64e-03	10	115	2	IPR002495
Domain	FN3_dom	FN1 DSCAML1 TYRO3 ANOS1 PTPRM SDK1	1.87e-03	209	115	6	IPR003961
Domain	GBD/FH3_dom	FHOD3 DAAM1	1.99e-03	11	115	2	IPR014768
Domain	GBD_FH3	FHOD3 DAAM1	1.99e-03	11	115	2	PS51232
Domain	ABC_transporter_CS	ABCC5 ABCB6 ABCC9	2.19e-03	42	115	3	IPR017871
Domain	MIRO-like	LRRK1 AGAP1	2.80e-03	13	115	2	IPR013684
Domain	Roc	LRRK1 AGAP1	2.80e-03	13	115	2	PF08477
Domain	ABC_tran	ABCC5 ABCB6 ABCC9	3.21e-03	48	115	3	PF00005
Domain	ABC_TRANSPORTER_2	ABCC5 ABCB6 ABCC9	3.21e-03	48	115	3	PS50893
Domain	RasGAP	IQGAP2 IQGAP3	3.26e-03	14	115	2	SM00323
Domain	SEA	MUC16 ADGRF5	3.26e-03	14	115	2	SM00200
Domain	RasGAP_CS	IQGAP2 IQGAP3	3.26e-03	14	115	2	IPR023152
Domain	EGF_3	RELN ZAN ADAM21 MALRD1 MEGF8 LRP1	3.35e-03	235	115	6	PS50026
Domain	ABC_TRANSPORTER_1	ABCC5 ABCB6 ABCC9	3.41e-03	49	115	3	PS00211
Domain	ABC_transporter-like	ABCC5 ABCB6 ABCC9	3.61e-03	50	115	3	IPR003439
Domain	RasGAP	IQGAP2 IQGAP3	3.74e-03	15	115	2	PF00616
Domain	BAR	SH3GL2 SH3GL3	3.74e-03	15	115	2	SM00721
Domain	RAS_GTPASE_ACTIV_1	IQGAP2 IQGAP3	3.74e-03	15	115	2	PS00509
Domain	-	MUC16 ADGRF5	3.74e-03	15	115	2	3.30.70.960
Domain	FH2	FHOD3 DAAM1	3.74e-03	15	115	2	PS51444
Domain	FH2_Formin	FHOD3 DAAM1	3.74e-03	15	115	2	IPR015425
Domain	FH2	FHOD3 DAAM1	3.74e-03	15	115	2	PF02181
Domain	Spectrin_alpha_SH3	SH3GL2 SH3GL3	3.74e-03	15	115	2	IPR013315
Domain	RAS_GTPASE_ACTIV_2	IQGAP2 IQGAP3	3.74e-03	15	115	2	PS50018
Domain	BAR	SH3GL2 SH3GL3	3.74e-03	15	115	2	PF03114
Domain	FH2	FHOD3 DAAM1	3.74e-03	15	115	2	SM00498
Domain	MAM_1	ZAN PTPRM	4.26e-03	16	115	2	PS00740
Domain	BAR_dom	SH3GL2 SH3GL3	4.26e-03	16	115	2	IPR004148
Domain	-	IQGAP2 IQGAP3	4.26e-03	16	115	2	1.10.506.10
Domain	Ald_DH_CS_GLU	ALDH2 ALDH1B1	4.26e-03	16	115	2	IPR029510
Domain	EGF-like_dom	RELN ZAN ADAM21 MALRD1 MEGF8 LRP1	4.44e-03	249	115	6	IPR000742
Domain	Ald_DH_CS_CYS	ALDH2 ALDH1B1	4.81e-03	17	115	2	IPR016160
Domain	Channel_four-helix_dom	CACNA1D SCN4A CACNA1I	5.23e-03	57	115	3	IPR027359
Domain	-	CACNA1D SCN4A CACNA1I	5.23e-03	57	115	3	1.20.120.350
Domain	ALDEHYDE_DEHYDR_CYS	ALDH2 ALDH1B1	5.39e-03	18	115	2	PS00070
Domain	ALDEHYDE_DEHYDR_GLU	ALDH2 ALDH1B1	5.39e-03	18	115	2	PS00687
Domain	RasGAP_dom	IQGAP2 IQGAP3	5.39e-03	18	115	2	IPR001936
Domain	EGF_2	RELN ZAN ADAM21 MALRD1 MEGF8 LRP1	5.99e-03	265	115	6	PS01186
Domain	BAR	SH3GL2 SH3GL3	6.00e-03	19	115	2	PS51021
Domain	-	ALDH2 ALDH1B1	6.00e-03	19	115	2	3.40.605.10
Domain	Aldedh	ALDH2 ALDH1B1	6.00e-03	19	115	2	PF00171
Domain	Ald_DH_C	ALDH2 ALDH1B1	6.00e-03	19	115	2	IPR016163
Domain	Ald_DH_N	ALDH2 ALDH1B1	6.00e-03	19	115	2	IPR016162
Domain	Ald_DH/histidinol_DH	ALDH2 ALDH1B1	6.00e-03	19	115	2	IPR016161
Domain	Aldehyde_DH_dom	ALDH2 ALDH1B1	6.00e-03	19	115	2	IPR015590
Domain	-	ALDH2 ALDH1B1	6.00e-03	19	115	2	3.40.309.10
Pubmed	Association study between single-nucleotide polymorphisms in 199 drug-related genes and commonly measured quantitative traits of 752 healthy Japanese subjects.	NAT2 ABCC5 ABCB6 ABCC9 DDOST ALDH2 ALDH1B1	4.56e-06	193	118	7	19343046
Pubmed	Cell Surface Proteomic Map of HIV Infection Reveals Antagonism of Amino Acid Metabolism by Vpu and Nef.	TMEM237 PIEZO1 TNFRSF21 TYRO3 EIF2B5 NCKAP1L	6.20e-06	132	118	6	26439863
Pubmed	Localization and functional analysis of the LARGE family of glycosyltransferases: significance for muscular dystrophy.	LARGE2 LARGE1	1.14e-05	2	118	2	15661757
Pubmed	Synergistic association between two alcohol metabolism relevant genes and coronary artery disease among Chinese hypertensive patients.	ALDH2 ALDH1B1	1.14e-05	2	118	2	25047496
Pubmed	Telomere shortening in the esophagus of Japanese alcoholics: relationships with chromoendoscopic findings, ALDH2 and ADH1B genotypes and smoking history.	ALDH2 ALDH1B1	1.14e-05	2	118	2	23667679
Pubmed	LARGE2 generates the same xylose- and glucuronic acid-containing glycan structures as LARGE.	LARGE2 LARGE1	1.14e-05	2	118	2	23135544
Pubmed	PTPRM methylation induced by FN1 promotes the development of glioblastoma by activating STAT3 signalling.	FN1 PTPRM	1.14e-05	2	118	2	34225581
Pubmed	Characterization of the LARGE family of putative glycosyltransferases associated with dystroglycanopathies.	LARGE2 LARGE1	1.14e-05	2	118	2	15958417
Pubmed	Reduced expression of IQGAP2 and higher expression of IQGAP3 correlates with poor prognosis in cancers.	IQGAP2 IQGAP3	1.14e-05	2	118	2	29073199
Pubmed	LARGE2 facilitates the maturation of alpha-dystroglycan more effectively than LARGE.	LARGE2 LARGE1	1.14e-05	2	118	2	15752776
Pubmed	Mutation of Large, which encodes a putative glycosyltransferase, in an animal model of muscular dystrophy.	LARGE2 LARGE1	1.14e-05	2	118	2	12417403
Pubmed	Activated microglia in cortex of mouse models of mucopolysaccharidoses I and IIIB.	NAGLU IDUA	1.14e-05	2	118	2	12576554
Pubmed	The low density lipoprotein receptor-related protein mediates fibronectin catabolism and inhibits fibronectin accumulation on cell surfaces.	FN1 LRP1	1.14e-05	2	118	2	11867643
Pubmed	α2δ2 Controls the Function and Trans-Synaptic Coupling of Cav1.3 Channels in Mouse Inner Hair Cells and Is Essential for Normal Hearing.	CACNA1D CACNA2D2	1.14e-05	2	118	2	27798183
Pubmed	Comparative genomics, molecular evolution and computational modeling of ALDH1B1 and ALDH2.	ALDH2 ALDH1B1	1.14e-05	2	118	2	23247008
Pubmed	LRP1 is required for novobiocin-mediated fibronectin turnover.	FN1 LRP1	1.14e-05	2	118	2	30061663
Pubmed	Role of aldehyde dehydrogenases, alcohol dehydrogenase 1B genotype, alcohol consumption, and their combination in breast cancer in East-Asian women.	ALDH2 ALDH1B1	1.14e-05	2	118	2	32300124
Pubmed	Xylosyl- and glucuronyltransferase functions of LARGE in α-dystroglycan modification are conserved in LARGE2.	LARGE2 LARGE1	1.14e-05	2	118	2	23125099
Pubmed	Reelin and aromatase cooperate in ovarian follicle development.	RELN CYP19A1	1.14e-05	2	118	2	29880879
Pubmed	Molecular genetics of successful smoking cessation: convergent genome-wide association study results.	CD109 DSCAML1 OLFM3 ADGRF5 LARGE1	2.52e-05	101	118	5	18519826
Pubmed	Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry.	FN1 CD109 ADGRG6 MEGF8 PTPRM LRP1 ADGRF5	2.91e-05	257	118	7	16335952
Pubmed	Neuropathology in mouse models of mucopolysaccharidosis type I, IIIA and IIIB.	NAGLU IDUA	3.42e-05	3	118	2	22558223
Pubmed	The biology of IQGAP proteins: beyond the cytoskeleton.	IQGAP2 IQGAP3	3.42e-05	3	118	2	25722290
Pubmed	Discovery of a Role for Rab3b in Habituation and Cocaine Induced Locomotor Activation in Mice Using Heterogeneous Functional Genomic Analysis.	RAB3D RAB3B	3.42e-05	3	118	2	32742255
Pubmed	Crystal structure of eta-crystallin: adaptation of a class 1 aldehyde dehydrogenase for a new role in the eye lens.	ALDH2 ALDH1B1	3.42e-05	3	118	2	12693930
Pubmed	Involvement of IQGAP family proteins in the regulation of mammalian cell cytokinesis.	IQGAP2 IQGAP3	3.42e-05	3	118	2	25229330
Pubmed	Identification of the endophilins (SH3p4/p8/p13) as novel binding partners for the beta1-adrenergic receptor.	SH3GL2 SH3GL3	3.42e-05	3	118	2	10535961
Pubmed	The association of ADH and ALDH gene variants with alcohol drinking habits and cardiovascular disease risk factors.	ALDH2 ALDH1B1	3.42e-05	3	118	2	18782342
Pubmed	Src homology 3-domain growth factor receptor-bound 2-like (endophilin) interacting protein 1, a novel neuronal protein that regulates energy balance.	SH3GL2 SH3GL3	3.42e-05	3	118	2	15919751
Pubmed	Cloning and characterization of the murine Imitation Switch (ISWI) genes: differential expression patterns suggest distinct developmental roles for Snf2h and Snf2l.	SMARCA1 SMARCA2	3.42e-05	3	118	2	11359880
Pubmed	Contribution of the alcohol dehydrogenase-1B genotype and oral microorganisms to high salivary acetaldehyde concentrations in Japanese alcoholic men.	ALDH2 ALDH1B1	3.42e-05	3	118	2	17471563
Pubmed	Evaluation of heparin cofactor II-thrombin complex as a biomarker on blood spots from mucopolysaccharidosis I, IIIA and IIIB mice.	NAGLU IDUA	3.42e-05	3	118	2	19926322
Pubmed	Mitochondrial NAD dependent aldehyde dehydrogenase either from yeast or human replaces yeast cytoplasmic NADP dependent aldehyde dehydrogenase for the aerobic growth of yeast on ethanol.	ALDH2 ALDH1B1	3.42e-05	3	118	2	23454351
Pubmed	IQGAP proteins reveal an atypical phosphoinositide (aPI) binding domain with a pseudo C2 domain fold.	IQGAP2 IQGAP3	3.42e-05	3	118	2	22493426
Pubmed	Endogenous glucuronyltransferase activity of LARGE or LARGE2 required for functional modification of α-dystroglycan in cells and tissues.	LARGE2 LARGE1	3.42e-05	3	118	2	25138275
Pubmed	Molecular genetics of human aldehyde dehydrogenase.	ALDH2 ALDH1B1	3.42e-05	3	118	2	1306115
Pubmed	Large-scale proteomics and phosphoproteomics of urinary exosomes.	CUL4B FN1 IQGAP2 PPFIA2 NAGLU RAB3D ABCB6 SLC44A4 SLC5A2 MEGF8 ALDH2 RAB3B FIGNL1	4.29e-05	1016	118	13	19056867
Pubmed	E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.	FN1 MYO7A PPFIA2 NAGLU RNF213 UNC93A DSCAML1 DDOST SLC5A2 IGF2BP3 RGL4	4.36e-05	736	118	11	29676528
Pubmed	Comparison of an expanded ataxia interactome with patient medical records reveals a relationship between macular degeneration and ataxia.	FN1 NELFCD MEGF8 LRP1 GOLGA3	5.32e-05	118	118	5	21078624
Pubmed	Rab3 proteins involved in vesicle biogenesis and priming in embryonic mouse chromaffin cells.	RAB3D RAB3B	6.82e-05	4	118	2	20716109
Pubmed	EEN encodes for a member of a new family of proteins containing an Src homology 3 domain and is the third gene located on chromosome 19p13 that fuses to MLL in human leukemia.	SH3GL2 SH3GL3	6.82e-05	4	118	2	9122235
Pubmed	Genetic determinants of both ethanol and acetaldehyde metabolism influence alcohol hypersensitivity and drinking behaviour among Scandinavians.	ALDH2 ALDH1B1	6.82e-05	4	118	2	20205700
Pubmed	Endophilin-A coordinates priming and fusion of neurosecretory vesicles via intersectin.	SH3GL2 SH3GL3	6.82e-05	4	118	2	32152276
Pubmed	LRRK2 controls an EndoA phosphorylation cycle in synaptic endocytosis.	SH3GL2 SH3GL3	6.82e-05	4	118	2	22998870
Pubmed	Localization versus function of Rab3 proteins. Evidence for a common regulatory role in controlling fusion.	RAB3D RAB3B	6.82e-05	4	118	2	12167638
Pubmed	A complete genetic analysis of neuronal Rab3 function.	RAB3D RAB3B	6.82e-05	4	118	2	15269275
Pubmed	Synaptojanin and Endophilin Mediate Neck Formation during Ultrafast Endocytosis.	SH3GL2 SH3GL3	6.82e-05	4	118	2	29953872
Pubmed	GDP/GTP exchange factor MADD drives activation and recruitment of secretory Rab GTPases to Weibel-Palade bodies.	RAB3D RAB3B	6.82e-05	4	118	2	34551092
Pubmed	Defects in the medial entorhinal cortex and dentate gyrus in the mouse model of Sanfilippo syndrome type B.	NAGLU IDUA	6.82e-05	4	118	2	22096577
Pubmed	The polarity protein Inturned links NPHP4 to Daam1 to control the subapical actin network in multiciliated cells.	NPHP4 DAAM1	6.82e-05	4	118	2	26644512
Pubmed	Valosin-containing protein (VCP) is a novel IQ motif-containing GTPase activating protein 1 (IQGAP1)-interacting protein.	IQGAP2 IQGAP3	6.82e-05	4	118	2	28970065
Pubmed	Expression and protein-binding studies of the EEN gene family, new interacting partners for dynamin, synaptojanin and huntingtin proteins.	SH3GL2 SH3GL3	6.82e-05	4	118	2	10816441
Pubmed	Rab3 superprimes synaptic vesicles for release: implications for short-term synaptic plasticity.	RAB3D RAB3B	6.82e-05	4	118	2	16436611
Pubmed	The SH3p4/Sh3p8/SH3p13 protein family: binding partners for synaptojanin and dynamin via a Grb2-like Src homology 3 domain.	SH3GL2 SH3GL3	6.82e-05	4	118	2	9238017
Pubmed	Isoprenylcysteine carboxyl methyltransferase deficiency in mice.	RAB3D RAB3B	6.82e-05	4	118	2	11121396
Pubmed	Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.	KLHL6 LARGE2 SESTD1 FN1 B3GNT5 IQGAP2 SH3GL3 PEX1 RAB3D PACS1 TYW1B ESPL1 NCKAP1L	8.26e-05	1084	118	13	11544199
Pubmed	Cytoplasmic Metadherin (MTDH) provides survival advantage under conditions of stress by acting as RNA-binding protein.	FN1 PPFIA2 CD109 RNF213 LRP1 SDK1	9.40e-05	214	118	6	22199357
Pubmed	Tctex-1, a novel interaction partner of Rab3D, is required for osteoclastic bone resorption.	RAB3D RAB3B	1.13e-04	5	118	2	21262767
Pubmed	The nuclear envelope protein MAN1 regulates TGFbeta signaling and vasculogenesis in the embryonic yolk sac.	FN1 LEMD3	1.13e-04	5	118	2	17329363
Pubmed	Upregulation of Parkin in endophilin mutant mice.	SH3GL2 SH3GL3	1.13e-04	5	118	2	25471590
Pubmed	Tumor suppressor function of laminin-binding alpha-dystroglycan requires a distinct beta3-N-acetylglucosaminyltransferase.	LARGE2 LARGE1	1.13e-04	5	118	2	19587235
Pubmed	Rab3a is involved in transport of synaptic vesicles to the active zone in mouse brain nerve terminals.	RAB3D RAB3B	1.13e-04	5	118	2	11598194
Pubmed	The association of alcohol and alcohol metabolizing gene variants with diabetes and coronary heart disease risk factors in a white population.	ALDH2 ALDH1B1	1.13e-04	5	118	2	20700531
Pubmed	Alix (ALG-2-interacting protein X), a protein involved in apoptosis, binds to endophilins and induces cytoplasmic vacuolization.	SH3GL2 SH3GL3	1.13e-04	5	118	2	12034747
Pubmed	Endophilin-A Deficiency Induces the Foxo3a-Fbxo32 Network in the Brain and Causes Dysregulation of Autophagy and the Ubiquitin-Proteasome System.	SH3GL2 SH3GL3	1.13e-04	5	118	2	27720640
Pubmed	Noc2 is essential in normal regulation of exocytosis in endocrine and exocrine cells.	RAB3D RAB3B	1.13e-04	5	118	2	15159548
Pubmed	Large-scale analysis of ion channel gene expression in the mouse heart during perinatal development.	CACNA1D CACNA2D2 ABCC9 SCN4A SCNN1B	1.16e-04	139	118	5	16985003
Pubmed	The interaction between EEN and Abi-1, two MLL fusion partners, and synaptojanin and dynamin: implications for leukaemogenesis.	SH3GL2 SH3GL3	1.70e-04	6	118	2	10764144
Pubmed	Roles of Brahma and Brahma/SWI2-related gene 1 in hypoxic induction of the erythropoietin gene.	SMARCA1 SMARCA2	1.70e-04	6	118	2	15347669
Pubmed	Endophilin, Lamellipodin, and Mena cooperate to regulate F-actin-dependent EGF-receptor endocytosis.	SH3GL2 SH3GL3	1.70e-04	6	118	2	24076656
Pubmed	IQ-motif selectivity in human IQGAP2 and IQGAP3: binding of calmodulin and myosin essential light chain.	IQGAP2 IQGAP3	1.70e-04	6	118	2	21299499
Pubmed	Binding properties of SH3 peptide ligands identified from phage-displayed random peptide libraries.	SH3GL2 SH3GL3	1.70e-04	6	118	2	9238627
Pubmed	Deciphering the structure and function of Als2cr4 in the mouse retina.	NRL TMEM237	1.70e-04	6	118	2	20375344
Pubmed	The RAB3-RIM Pathway Is Essential for the Release of Neuromodulators.	RAB3D RAB3B	1.70e-04	6	118	2	31679900
Pubmed	New insights into the function and regulation of vitamin D target proteins.	CACNA1D SMARCA2	1.70e-04	6	118	2	17257825
Pubmed	Role of dynamin, synaptojanin, and endophilin in podocyte foot processes.	SH3GL2 SH3GL3	1.70e-04	6	118	2	23187129
Pubmed	Rab3D is not required for exocrine exocytosis but for maintenance of normally sized secretory granules.	RAB3D RAB3B	1.70e-04	6	118	2	12192047
Pubmed	A novel SH3-containing human gene family preferentially expressed in the central nervous system.	SH3GL2 SH3GL3	1.70e-04	6	118	2	9169142
Pubmed	An AXL/LRP-1/RANBP9 complex mediates DC efferocytosis and antigen cross-presentation in vivo.	TYRO3 LRP1	1.70e-04	6	118	2	24509082
Pubmed	Biochemical dissection of Anosmin-1 interaction with FGFR1 and components of the extracellular matrix.	FN1 ANOS1	1.70e-04	6	118	2	20874775
Pubmed	Endophilin A1 regulates dendritic spine morphogenesis and stability through interaction with p140Cap.	SH3GL2 SH3GL3	2.37e-04	7	118	2	25771685
Pubmed	Rep15 interacts with several Rab GTPases and has a distinct fold for a Rab effector.	RAB3D RAB3B	2.37e-04	7	118	2	35871249
Pubmed	HIV-1 Nef assembles a Src family kinase-ZAP-70/Syk-PI3K cascade to downregulate cell-surface MHC-I.	PACS1 SYK	2.37e-04	7	118	2	18005690
Pubmed	Synaptojanin forms two separate complexes in the nerve terminal. Interactions with endophilin and amphiphysin.	SH3GL2 SH3GL3	2.37e-04	7	118	2	9341169
Pubmed	The SH3 domains of endophilin and amphiphysin bind to the proline-rich region of synaptojanin 1 at distinct sites that display an unconventional binding specificity.	SH3GL2 SH3GL3	2.37e-04	7	118	2	10542231
Pubmed	The ATP-Binding Cassette Gene ABCF1 Functions as an E2 Ubiquitin-Conjugating Enzyme Controlling Macrophage Polarization to Dampen Lethal Septic Shock.	TRAF3 SYK	2.37e-04	7	118	2	30770245
Pubmed	Mono-ubiquitination of Rabphilin 3A by UBE3A serves a non-degradative function.	RAB3D RAB3B	2.37e-04	7	118	2	33542309
Pubmed	Maternal aldehyde elimination during pregnancy preserves the fetal genome.	ALDH2 ALDH1B1	2.37e-04	7	118	2	25155611
Pubmed	140 mouse brain proteins identified by Ca2+-calmodulin affinity chromatography and tandem mass spectrometry.	GLTP SH3GL2 RAB3D PACS1 RAB3B	2.43e-04	163	118	5	16512683
Pubmed	Genetic determinants of height growth assessed longitudinally from infancy to adulthood in the northern Finland birth cohort 1966.	SH3GL3 ADGRG6 NHEJ1	2.72e-04	37	118	3	19266077
Pubmed	Allele frequencies of single nucleotide polymorphisms (SNPs) in 40 candidate genes for gene-environment studies on cancer: data from population-based Japanese random samples.	NAT2 CYP19A1 ALDH2	2.95e-04	38	118	3	14634838
Pubmed	Evolutionary insights into T-type Ca2+ channel structure, function, and ion selectivity from the Trichoplax adhaerens homologue.	CACNA1D CACNA1I	3.15e-04	8	118	2	28330839
Pubmed	Reeler/Disabled-like disruption of neuronal migration in knockout mice lacking the VLDL receptor and ApoE receptor 2.	RELN LRP1	3.15e-04	8	118	2	10380922
Pubmed	Ataxin-2 and huntingtin interact with endophilin-A complexes to function in plastin-associated pathways.	SH3GL2 SH3GL3	3.15e-04	8	118	2	16115810
Pubmed	Recruitment of endophilin to clathrin-coated pit necks is required for efficient vesicle uncoating after fission.	SH3GL2 SH3GL3	3.15e-04	8	118	2	22099461
Pubmed	SH3 domains from a subset of BAR proteins define a Ubl-binding domain and implicate parkin in synaptic ubiquitination.	SH3GL2 SH3GL3	3.15e-04	8	118	2	20064468
Pubmed	Ataxin-2 associates with the endocytosis complex and affects EGF receptor trafficking.	SH3GL2 SH3GL3	3.15e-04	8	118	2	18602463
Pubmed	Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB.	FN1 IQGAP2 LEMD3 MUC16 ABCC5 RNF213 IGF2BP3 SDK1 GOLGA3 AGAP1	3.26e-04	777	118	10	35844135
Pubmed	A large-scale candidate gene association study of age at menarche and age at natural menopause.	CHRNA9 B3GNT5 CYP19A1 ANOS1 EIF2B5 ALDH1B1	3.64e-04	275	118	6	20734064
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	ENGASE CLTCL1 MYO7A PIEZO1 NAGLU LRRK1 IDUA NPHP4 TNFRSF21 MEGF8 ESPL1 IQGAP3	3.87e-04	1105	118	12	35748872
Interaction	PSCA interactions	LARGE2 CACNA2D2 CD109 UNC93A IDUA AIG1 APOL2 LARGE1	2.03e-06	147	115	8	int:PSCA
Interaction	RLN1 interactions	LARGE2 CACNA2D2 ADAM21 NAGLU CD109 LARGE1	1.54e-05	93	115	6	int:RLN1
Interaction	IFNE interactions	LARGE2 CACNA2D2 NAGLU CD109	1.60e-05	27	115	4	int:IFNE
Interaction	PRR5-ARHGAP8 interactions	SH3GL2 SH3GL3 ZMYND12	2.11e-05	10	115	3	int:PRR5-ARHGAP8
Cytoband	Ensembl 112 genes in cytogenetic band chr3q27	KLHL6 B3GNT5 ABCC5 EIF2B5	3.46e-04	128	118	4	chr3q27
Cytoband	15q15	TYRO3 SLC28A2	4.25e-04	12	118	2	15q15
GeneFamily	Fibronectin type III domain containing	FN1 DSCAML1 TYRO3 ANOS1 PTPRM SDK1	4.22e-05	160	72	6	555
GeneFamily	Calcium voltage-gated channel subunits	CACNA1D CACNA2D2 CACNA1I	1.47e-04	26	72	3	253
GeneFamily	Blood group antigens\|CD molecules\|I-set domain containing\|Immunoglobulin like domain containing	DSCAML1 TYRO3 PTPRM ADGRF5 SDK1	4.55e-04	161	72	5	593
GeneFamily	Glycosyltransferase family 8	LARGE2 LARGE1	5.53e-04	9	72	2	436
GeneFamily	N-BAR domain containing	SH3GL2 SH3GL3	1.01e-03	12	72	2	1289
GeneFamily	Immunoglobulin like domain containing	DSCAML1 TYRO3 PTPRM ADGRF5 SDK1	1.03e-03	193	72	5	594
GeneFamily	ATP binding cassette subfamily C	ABCC5 ABCC9	1.19e-03	13	72	2	807
GeneFamily	X-linked mental retardation\|Rho GTPase activating proteins\|BAR-PH domain containing	AGAP5 AGAP1	2.05e-03	17	72	2	1291
GeneFamily	Aldehyde dehydrogenases	ALDH2 ALDH1B1	2.56e-03	19	72	2	398
GeneFamily	ArfGAPs	AGAP5 AGAP1	7.62e-03	33	72	2	395
Coexpression	GSE2405_HEAT_KILLED_LYSATE_VS_LIVE_A_PHAGOCYTOPHILUM_STIM_NEUTROPHIL_24H_DN	CPNE2 DDX31 PIEZO1 ABCC9 LOXL1 SYK CTSE IQGAP3	3.14e-06	200	116	8	M6201
ToppCell	facs-Pancreas-Endocrine-3m-Epithelial-pancreatic_D_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CACNA2D2 PPFIA2 OLFM3 SMARCA1 SMARCA2 ADGRF5 RAB3B	6.94e-07	189	117	7	fcc3713e8200d51074f709f3360fb36efb0a639f
ToppCell	COPD-Lymphoid-B\|Lymphoid / Disease state, Lineage and Cell class	KLHL6 SESTD1 TRAF3 LRRK1 SYK GRAMD1C LARGE1	7.19e-07	190	117	7	1e85ee686ff6dd27c69415d524d54fa825b1daad
ToppCell	droplet-Pancreas-Endocrine-18m-Epithelial-pancreatic_D_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CACNA2D2 PPFIA2 OLFM3 SMARCA1 SMARCA2 ADGRF5 RAB3B	7.98e-07	193	117	7	6995ee29bf403a71247de92a37dfd851be5acf2e
ToppCell	Children_(3_yrs)-Immune-interstitial_macrophage_(C1Q_positive)-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	B3GNT5 IQGAP2 MYO7A ABCC5 SYK HRH2 ATG16L2	8.26e-07	194	117	7	663e7e7fe48157e808b4f1a0ea6ad41944e857a2
ToppCell	Bronchial-NucSeq-Immune_Myeloid-Macrophage_other-Macrophage_intravascular\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	B3GNT5 MYO7A ABCC5 SYK LRP1 HRH2 NCKAP1L	9.47e-07	198	117	7	c7dbf24caae5c4ef285845d13055de9e07281bb3
ToppCell	Children_(3_yrs)-Epithelial-lung_goblet_cell-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	MUC16 FHOD3 SLC44A4 SCNN1B TMC5 SDK1	4.31e-06	161	117	6	2d63b279d9a5132e1c09b03930bf9039036d24a2
ToppCell	droplet-Lung-3m-Hematologic-lymphocytic-Zbtb32+_B_cell-Zbtb32+_B_cell\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	B3GNT5 SCN4A SYK CACNA1I CTSE RAB3B	4.31e-06	161	117	6	7af3b0d4fc7967f6b3e2d255d23fd8b1fd01a7af
ToppCell	droplet-Lung-3m-Hematologic-lymphocytic-Zbtb32+_B_cell\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	B3GNT5 SCN4A SYK CACNA1I CTSE RAB3B	4.31e-06	161	117	6	98be0cf8228496b31f7f3e0efd8787e95eb626d1
ToppCell	PND01-Endothelial-Endothelial_lymphatic-Lymphatic_EC-LEC-LEC_mature\|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CPNE2 RELN SH3GL3 CD109 AIG1 CD300LG	5.69e-06	169	117	6	f077e39e41fffe7672541f5b72b80faaf56c597c
ToppCell	facs-Lung-Endomucin-3m-Mesenchymal-pericyte_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	WDR5B ADGRG6 PSTK SMARCA1 SCNN1B FOXO4	5.69e-06	169	117	6	2d23b4cee060f8adddc430c1c10d4e25205b4af6
ToppCell	facs-Lung-Endomucin-3m-Mesenchymal-Pericyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	WDR5B ADGRG6 PSTK SMARCA1 SCNN1B FOXO4	5.69e-06	169	117	6	ecaf08e8e0b54d1c97a02bc1f65409fd43d68227
ToppCell	facs-Lung-Endomucin-3m-Mesenchymal\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	WDR5B ADGRG6 PSTK SMARCA1 SCNN1B FOXO4	5.69e-06	169	117	6	ad6af6609acf158cb79e45ee7ca9af332be3c40c
ToppCell	5'-Parenchyma_lung-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophages-Alveolar_macrophages_L.1.0.5.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	FN1 RNF213 SYK LRP1 ATG16L2 NCKAP1L	6.73e-06	174	117	6	d5c22b43531414951666ee7542a66ed9380e2d14
ToppCell	Club_cells-SSc-ILD_01\|World / lung cells shred on cell class, cell subclass, sample id	SLC44A4 TNFRSF21 SCNN1B TMC5 CTSE SDK1	7.66e-06	178	117	6	be64d4be23fb96a4cdd7980c58880fdfe817747f
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Outer_Medullary_Collecting_Duct_Principal_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	CACNA2D2 PIEZO1 SH3GL2 FHOD3 SCNN1B SMARCA2	7.91e-06	179	117	6	d3438fed0d85d5ed5afa8ff820c45143d77b6c0d
ToppCell	droplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_D_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CACNA2D2 PPFIA2 SMARCA1 SMARCA2 SAMD14 RAB3B	8.17e-06	180	117	6	8bf6e8b6b45ce42f8c5f23e7cd1752ec8b3fa2d2
ToppCell	droplet-Kidney-KIDNEY-30m-Epithelial-collecting_duct_principal_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CACNA1D ADGRG6 SMARCA1 SCNN1B SAMD14 SDK1	8.43e-06	181	117	6	7af469f5bcb9b1ab3f35b2758bf2afb87e8eba57
ToppCell	Control-Epithelial_cells-Airway_club\|Control / group, cell type (main and fine annotations)	SCNN1B ADGRF5 TMC5 CTSE SDK1 AGAP1	8.43e-06	181	117	6	c755d23dd9aabc717dc73e2b3fa99a1f751e6507
ToppCell	droplet-Trachea-3m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l44-58\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CACNA1D WDR5B MYO7A FOXO4 SAMD14 GOLGA3	8.97e-06	183	117	6	dc9602bed3136db91faeffef177006246dc92743
ToppCell	facs-Lung-EPCAM-24m-Lymphocytic-B_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	B3GNT5 SCN4A SYK CACNA1I CTSE RAB3B	8.97e-06	183	117	6	1614704fe0d8cd4c54c49f93f0cefb790ca897c7
ToppCell	3'_v3-lymph-node_spleen-Hematopoietic_progenitors-Cycling_pre-Myeloid-1\|lymph-node_spleen / Manually curated celltypes from each tissue	CLTCL1 B3GNT5 CD109 RAB3D HRH2 IQGAP3	9.26e-06	184	117	6	f93373fcde5c31f4ffe67ca0f3ea7f4e906dc88b
ToppCell	pdx-Tumor_cells-T0\|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)	CACNA1D RELN DSCAML1 PTPRM AIG1 LRP1	9.55e-06	185	117	6	1d874608aa2062024323512f68889219471b2f00
ToppCell	Fetal_29-31_weeks-Mesenchymal-pericyte_cell-D150\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	CNNM2 PPFIA2 ABCC9 ADGRG6 HRH2 ADGRF5	1.01e-05	187	117	6	fa01a61bfd13feb033ba1e35cf513707b1bff8c8
ToppCell	pdx-Tumor_cells-T5\|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)	CPNE2 IGF2BP3 KATNBL1 CACNA1I SDK1 AGAP1	1.01e-05	187	117	6	7e376831a11ee72ed87abcdac631ca46ae29c250
ToppCell	IPF-Lymphoid-B\|Lymphoid / Disease state, Lineage and Cell class	KLHL6 SESTD1 TRAF3 LRRK1 SYK LARGE1	1.01e-05	187	117	6	af1327559f7e01bec070881cae52834917c3da65
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	IQGAP2 PIEZO1 FHOD3 SYK SCNN1B SDK1	1.08e-05	189	117	6	fc88c51ace7d883c01617f3f9b5fab70cc91cc09
ToppCell	IPF-Epithelial-Club\|IPF / Disease state, Lineage and Cell class	SCNN1B ADGRF5 TMC5 CTSE SDK1 AGAP1	1.08e-05	189	117	6	f3fcef008ef252b29ac6d567fef27f9acf9cd70f
ToppCell	368C-Epithelial_cells\|368C / Donor, Lineage, Cell class and subclass (all cells)	CACNA2D2 SLC44A4 SCNN1B ADGRF5 TMC5 CTSE	1.11e-05	190	117	6	459811e88d3001816c2d89034e0921c24918c17f
ToppCell	COVID-19-Epithelial_cells-Airway_goblet\|COVID-19 / group, cell type (main and fine annotations)	MUC16 SLC44A4 SCNN1B TMC5 SDK1 AGAP1	1.11e-05	190	117	6	51ca9ef4df3220487152fcf684147730637c7cc1
ToppCell	IPF-Epithelial-Club\|World / Disease state, Lineage and Cell class	SCNN1B ADGRF5 TMC5 CTSE SDK1 AGAP1	1.14e-05	191	117	6	3c88a6f1d74bb3b9173cd0ea3a63c6d9570e3954
ToppCell	COVID-19-lung-Macrophage_PPARGhi_CD5Lhi\|lung / Disease (COVID-19 only), tissue and cell type	KLHL6 B3GNT5 IQGAP2 SYK LRP1 NCKAP1L	1.14e-05	191	117	6	dab953682b8c9ed680a799161f837f792a7e4f33
ToppCell	COVID-19-lung-Macrophage_PPARGhi_CD5Lhi\|COVID-19 / Disease (COVID-19 only), tissue and cell type	KLHL6 B3GNT5 IQGAP2 SYK LRP1 NCKAP1L	1.18e-05	192	117	6	bcfb9c005166bc0b4f8ee2dfc0c1540e8bf0e1ff
ToppCell	droplet-Pancreas-Endocrine-21m-Epithelial-pancreatic_D_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CACNA2D2 PPFIA2 SMARCA1 ADGRF5 SAMD14 RAB3B	1.18e-05	192	117	6	550a6574a93acadb43c449094565c73ca51a0c5c
ToppCell	COPD-Epithelial-Ciliated\|World / Disease state, Lineage and Cell class	IQCH TSPAN19 MUC16 SLC44A4 TMC5 CFAP46	1.18e-05	192	117	6	eab1105cd1a98cfcd3d74dc5c9b89e1799bba59e
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell_\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	FN1 CD109 PTPRM SCN4A CD300LG ADGRF5	1.18e-05	192	117	6	c0e59e642b42c055cf73d029cf54d07d9b719359
ToppCell	Club_cells-Myositis-ILD_01\|World / lung cells shred on cell class, cell subclass, sample id	MUC16 ABCC5 SLC44A4 SCNN1B TMC5 CTSE	1.21e-05	193	117	6	6582c0367052b9d10fb629c383ee0c55872afd2d
ToppCell	Adult-Immune-interstitial_macrophage_(C1Q_positive)\|Adult / Lineage, Cell type, age group and donor	IQGAP2 MYO7A ABCC5 LRP1 HRH2 NCKAP1L	1.21e-05	193	117	6	31c0978ba78c9516d498aec0798902e57555e557
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Inner_Medullary_Collecting_Duct_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	B3GNT5 TNFRSF21 ADGRG6 PTPRM TMC5 SDK1	1.21e-05	193	117	6	a5695ce2e24a62026ae28f3dea07ca4a435206b8
ToppCell	Club_cells\|World / lung cells shred on cell class, cell subclass, sample id	MUC16 ABCC5 SLC44A4 SCNN1B TMC5 CTSE	1.21e-05	193	117	6	9d3165dc5763a07a7d873f497624d9d6528fa2db
ToppCell	droplet-Pancreas-Endocrine-18m-Epithelial-pancreatic_D_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CACNA2D2 PPFIA2 OLFM3 SMARCA1 ADGRF5 RAB3B	1.21e-05	193	117	6	7fcfb0f76789fa8d8caa18304cb43c8fd899a81b
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	PIEZO1 TNFRSF21 ADGRG6 SCNN1B TMC5 SDK1	1.25e-05	194	117	6	4579b4a44f7c731553a284843c296866027d7c0e
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	IQGAP2 PIEZO1 UNC93A ANOS1 TMC5 SDK1	1.25e-05	194	117	6	69bff17df4a760ccf081cf52ff04af02c14f448d
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	FN1 CD109 PTPRM SCN4A CD300LG ADGRF5	1.25e-05	194	117	6	e55dc30e200c9f576804acb642175eb4fa9146b5
ToppCell	IPF-Multiplet-Multiplet\|IPF / Disease state, Lineage and Cell class	TSPAN19 ADGRF5 TMC5 SDK1 CFAP46 AGAP1	1.29e-05	195	117	6	fce0c29574bb7aab181b9c00feb42681e285d1f2
ToppCell	Bronchial-NucSeq-Immune_Lymphocytic-B-B_plasma-B_plasmablast\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	MYO7A TSPAN19 LRRK1 DDOST TYW1B IQGAP3	1.29e-05	195	117	6	a045fb8a377e54fb57fef1181d4c3fc15d627ef6
ToppCell	5'-Adult-SmallIntestine-Epithelial-Tuft-related\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ADGRG6 MALRD1 ALDH2 TMC5 CTSE ATG16L2	1.29e-05	195	117	6	23ab7e2a419377c05bab0e92a2457afbcd3d9e07
ToppCell	IPF-Multiplet-Multiplet\|World / Disease state, Lineage and Cell class	TSPAN19 SLC44A4 TMC5 SDK1 CFAP46 AGAP1	1.29e-05	195	117	6	21dbdc803c6947024dc2416e9e21c2ef0af9bc31
ToppCell	5'-Adult-SmallIntestine-Epithelial-Tuft-related-BEST4+_epithelial\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ADGRG6 MALRD1 ALDH2 TMC5 CTSE ATG16L2	1.29e-05	195	117	6	e87b11e3242fdbed2e7f383e6876ec375af32bd4
ToppCell	IPF-Multiplet\|IPF / Disease state, Lineage and Cell class	TSPAN19 ADGRF5 TMC5 SDK1 CFAP46 AGAP1	1.29e-05	195	117	6	eacc0449ae6f3ad8002268cd061467684c6fb9a7
ToppCell	COPD-Multiplet-Multiplet\|COPD / Disease state, Lineage and Cell class	TSPAN19 ADGRF5 TMC5 SDK1 CFAP46 AGAP1	1.33e-05	196	117	6	af4cdc61830685a888a1209826c23bcf54a43084
ToppCell	COPD-Multiplet\|COPD / Disease state, Lineage and Cell class	TSPAN19 ADGRF5 TMC5 SDK1 CFAP46 AGAP1	1.33e-05	196	117	6	6d02d494196e3f857d53eea46d9419690d43beca
ToppCell	Adult-Immune\|Adult / Lineage, Cell type, age group and donor	KLHL6 B3GNT5 IQGAP2 SYK LRP1 NCKAP1L	1.40e-05	198	117	6	9bfd7b88aa646eaf5eddb15cf985c7ca910cb35e
ToppCell	10x3'2.3-week_14-16-Endothelial\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	FN1 ABCC9 ADGRG6 PTPRM CD300LG ADGRF5	1.44e-05	199	117	6	41f046646fff65b7e51b63d3204f76ef32054781
ToppCell	Parenchymal-NucSeq-Immune_Myeloid\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	KLHL6 B3GNT5 IQGAP2 SYK LRP1 NCKAP1L	1.44e-05	199	117	6	7ee2805fd9143eba11bf6832267b62189683608b
ToppCell	10x3'2.3-week_14-16-Endothelial-stroma\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	FN1 ABCC9 ADGRG6 PTPRM CD300LG ADGRF5	1.44e-05	199	117	6	ef7f7f7c861827574b120f48cf4052c563929081
ToppCell	10x5'v1-week_14-16-Endothelial-stroma\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	FN1 ABCC9 ADGRG6 PTPRM CD300LG ADGRF5	1.49e-05	200	117	6	2488aa12970a43a5af352e2c36c73884d73a1cc5
ToppCell	Parenchymal-NucSeq-Epithelial-Epi_submucosal-gland-SMG_Duct\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	IQGAP2 MUC16 TNFRSF21 SCNN1B TMC5 SDK1	1.49e-05	200	117	6	b992eeddee38e6fe3564e9b1850f6b20b89bf47d
ToppCell	Biopsy_Other_PF-Epithelial\|Biopsy_Other_PF / Sample group, Lineage and Cell type	CACNA2D2 SLC44A4 SCNN1B ADGRF5 TMC5 CTSE	1.49e-05	200	117	6	1ef4d5ae698fa721e0f510bf0d918bd8d3b00591
ToppCell	Bronchial-NucSeq-Immune_Myeloid-Macrophage_other\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	KLHL6 MYO7A ABCC5 SYK LRP1 NCKAP1L	1.49e-05	200	117	6	78d75d381cb2b9a4c9eb7c32a07b014eaee39195
ToppCell	Control_saline-Mesenchymal_myocytic-Pericyte\|Control_saline / Treatment groups by lineage, cell group, cell type	CNNM2 PPFIA2 ABCC9 TYRO3 LRP1 HRH2	1.49e-05	200	117	6	cb7ef774b6d300f8019c5b16a04e3ebd165e4f1c
ToppCell	10x5'v1-week_14-16-Endothelial\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	FN1 ABCC9 ADGRG6 PTPRM CD300LG ADGRF5	1.49e-05	200	117	6	e786544cf6f891550c4be55ebb4928c92297b504
ToppCell	primary_visual_cortex-Neuronal-glutamatergic_neuron-L6b-L6b_VISp_Col8a1_Rxfp1\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	CPNE2 B3GNT5 ADGRG6 SLC28A2 ALDH1B1	2.50e-05	131	117	5	81efe8b0ca4377e557a42ddb12aecaf3f46b15bf
ToppCell	primary_visual_cortex-Neuronal-glutamatergic_neuron-L6b-L6b_VISp_Crh\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	CPNE2 B3GNT5 ADGRG6 ALDH1B1 SDK1	2.99e-05	136	117	5	44f03e4f55fb2c5f8b9397142c89f7194b009cc6
ToppCell	primary_visual_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Chrna2_Ptgdr\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	RELN CACNA2D2 PTPRM SAMD14 RAB3B	3.93e-05	144	117	5	71107275767a0728541a3695715c44874b3e5efc
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid-Macrophage_Dendritic-Classical_Dendritic_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	KLHL6 LRRK1 CD300LG IQGAP3 NCKAP1L	4.48e-05	148	117	5	12fa2c4922f03803006c606b1b16e79441e3bb13
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Degenerative_Inner_Medullary_Collecting_Duct_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PIEZO1 SH3GL2 UNC93A SLC44A4 ANOS1	5.59e-05	155	117	5	29c4e9947bb4f7e257ed5c3bcf21bd67f88d473f
ToppCell	10x5'-Liver-Myeloid_Mac-Intestinal_macrophages\|Liver / Manually curated celltypes from each tissue	ABCC5 ADGRG6 ANOS1 SMARCA1 LARGE1	5.76e-05	156	117	5	9a897fc79c4fae94c5f2e9012d65297f9225e5e3
ToppCell	LPS-antiTNF-Stromal_mesenchymal-Myocytic\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	CNNM2 PPFIA2 ABCC9 TNFRSF21 ADGRG6	5.76e-05	156	117	5	6365b69ede98bc866e996bc52736b00401aacf6f
ToppCell	droplet-Liver-Hepatocytes-24m-Myeloid\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GLTP LRRK1 TNFRSF21 SLC28A2 SYK	5.94e-05	157	117	5	ec433d2fe827abdb647be4176c231b7052482b6f
ToppCell	LPS-antiTNF-Stromal_mesenchymal-Myocytic-Pericyte_2\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	CNNM2 PPFIA2 ABCC9 TNFRSF21 ADGRG6	5.94e-05	157	117	5	bfec34182f052cf1c0d847ba53ea335d4d1190de
ToppCell	LPS-antiTNF-Epithelial_alveolar-AT_1-AT1\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	SH3GL2 SH3GL3 DSCAML1 ANOS1 SCNN1B	5.94e-05	157	117	5	9665a1375cfd8e9b8781c852686591226c0e0d9a
ToppCell	PND28-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_B-B-B_prolif\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	RELN TRMT2A SCNN1B FIGNL1 GOLGA3	5.94e-05	157	117	5	6730b775308f45a2f3946016bdbb7f8e5b5efe49
ToppCell	droplet-Lung-nan-3m-Lymphocytic-Zbtb32+_B\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	B3GNT5 SCN4A CACNA1I CTSE RAB3B	6.12e-05	158	117	5	66c011e9de002224f70725dfe8e7871c8d304492
ToppCell	3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.2.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	MUC16 SLC44A4 TMC5 ESPL1 SDK1	6.30e-05	159	117	5	60b1f4dce2ce0911160fda17f137c064da31e2eb
ToppCell	primary_visual_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Chrna2_Glra3\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	RELN CACNA2D2 PTPRM SAMD14 RAB3B	6.49e-05	160	117	5	0bfdaf979e6f128cba2928ce16bca4d3deff8ac9
ToppCell	LPS-IL1RA-Epithelial_alveolar-AT_1-AT1\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	SH3GL3 DTD2 DSCAML1 ANOS1 SCNN1B	6.69e-05	161	117	5	1e17a993126e1f2a25ee7dfbb95a74ccb2a26791
ToppCell	facs-Lung-Endomucin-24m-Lymphocytic-Zbtb32+_B\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	B3GNT5 SCN4A CTSE RAB3B IQGAP3	7.73e-05	166	117	5	6842735750dcb361e4c9844f05233b0fbb879652
ToppCell	facs-Kidney-nan-3m-Lymphocytic-B_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	B3GNT5 NPHP4 SYK CACNA1I ATG16L2	7.73e-05	166	117	5	6a948aefd283a2572da37b59dbc142b6e686b024
ToppCell	facs-Kidney-nan-3m-Lymphocytic-B_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	B3GNT5 NPHP4 SYK CACNA1I ATG16L2	7.73e-05	166	117	5	8d0c4eb90a2c006f96ae61d3d94c96fb64bc0c4d
ToppCell	facs-Heart-RV-24m-Lymphocytic-B_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	B3GNT5 SCN4A CACNA1I CTSE RAB3B	7.73e-05	166	117	5	16d42eda958b2a6f9d598e9b4b967505dee426ef
ToppCell	facs-Heart-RV-24m-Lymphocytic-B_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	B3GNT5 SCN4A CACNA1I CTSE RAB3B	7.73e-05	166	117	5	08d7db4ff1c9c9cea3a36a87b8690838e79d4e0e
ToppCell	facs-Lung-nan-3m-Myeloid-Classical_Monocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FN1 IQGAP2 TNFRSF21 SYK ALDH1B1	8.41e-05	169	117	5	05b138511039f1255a5f647040b1b9bdf222bd52
ToppCell	facs-Lung-nan-3m-Myeloid-classical_monocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FN1 IQGAP2 TNFRSF21 SYK ALDH1B1	8.41e-05	169	117	5	bf0a97f53d6e3f9ffeaeae0402b010c49a6cccb7
ToppCell	343B-Lymphocytic-CD4_T-cell-Proliferating_T_cell\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	CACNA1D ZNF285 ANOS1 ESPL1 IQGAP3	8.89e-05	171	117	5	4ccd88cf812dd8bfdc55159c6f504e9c84e4f4fc
ToppCell	droplet-Kidney-KIDNEY-1m-Myeloid-nan\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ENGASE DDX31 NEDD1 ADGRG6 ESPL1	8.89e-05	171	117	5	d9ad6a3bce3556abd24af1630bf4a99594437c3a
ToppCell	facs-BAT-Fat-3m-Myeloid-nan\|BAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SESTD1 FN1 IQGAP2 TNFRSF21 LRP1	9.13e-05	172	117	5	5f18c3f8eb8b7928901eede44c9b84b3c5efa1a9
ToppCell	droplet-Liver-Npc-18m-Endothelial-endothelial_cell_of_hepatic_sinusoid\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CPNE2 CD300LG ADGRF5 FSBP RAB3B	9.13e-05	172	117	5	a6fb1bde8d942c7b5caaf7bd14de0b7ce32fda55
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Ascending_Vasa_Recta_Endothelial_Cell_prolif\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	RELN FN1 ABCB6 PTPRM ADGRF5	9.13e-05	172	117	5	c056d44e2e130ceccadfcdceb192a7f095d779c8
ToppCell	droplet-Lung-3m-Hematologic-myeloid-Basophil/Mast_cell-basophil_l26\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	KLHL6 CPNE2 RMC1 CTSE DGAT1	9.39e-05	173	117	5	120dd20e8a71f9169a1596b6171df7aa0b96dd15
ToppCell	COVID-19-Heart-Neuronal\|Heart / Disease (COVID-19 only), tissue and cell type	RELN IQGAP2 CYP19A1 DTD2 ADGRG6	9.39e-05	173	117	5	6fb5f9e6536a5d57fd8e6657b494047a2d0bc9c7
ToppCell	Children_(3_yrs)-Epithelial-lung_goblet_cell-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	MUC16 FHOD3 SCNN1B TMC5 SDK1	9.39e-05	173	117	5	464267a2ff3f5c387b6c9c6fa4dab135a221f448
ToppCell	10x5'-lymph-node_spleen-Hematopoietic_progenitors-Cycling_pre-Myeloid-2\|lymph-node_spleen / Manually curated celltypes from each tissue	CYP19A1 LRP1 HRH2 ESPL1 IQGAP3	9.39e-05	173	117	5	783b8fa08b9d8f597f251793eae164151662f1f9
ToppCell	droplet-Lung-3m-Hematologic-myeloid-Basophil/Mast_cell\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	KLHL6 CPNE2 RMC1 CTSE DGAT1	9.39e-05	173	117	5	b2c55084ef6dac0e329c2e65c24cfe0045859c30
ToppCell	Immune_cells-Monocytes\|Immune_cells / Lineage and Cell class	GLTP FN1 TNFRSF21 LRP1 CD300LG	9.39e-05	173	117	5	3eced40a65453a023a1673658592e7e2a099119b
ToppCell	BAL-Mild-Epithelial-Epithelial-AT1/AT2\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	LARGE2 FHOD3 OLFM3 SCNN1B ADGRF5	9.64e-05	174	117	5	b7f5492ce8098f7eb0aef30ee558d00738d59d0e
ToppCell	BAL-Mild-Epithelial-Epithelial-AT1/AT2-\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	LARGE2 FHOD3 OLFM3 SCNN1B ADGRF5	9.64e-05	174	117	5	71730503be3d9c839c4c9e950145e2101d682a1c
ToppCell	BAL-Mild-Epithelial-Epithelial-AT1/AT2\|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)	LARGE2 FHOD3 OLFM3 SCNN1B ADGRF5	9.64e-05	174	117	5	ee8ac51fa0b426ad7b7453371bb79c8bf8c1d358
ToppCell	BAL-Mild-Epithelial-Epithelial-AT1/AT2-\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	LARGE2 FHOD3 OLFM3 SCNN1B ADGRF5	9.64e-05	174	117	5	cafe4d6b5f08d8888e9db6e196c66df991c03e7b
ToppCell	Basal_cells-Cryobiopsy_01\|World / lung cells shred on cell class, cell subclass, sample id	LARGE2 FHOD3 LOXL1 SCNN1B SDK1	9.64e-05	174	117	5	a0060be3940043015dcc49a5157de5541aed24a1
ToppCell	E16.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte-Pericyte_G2M\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ABCC9 TNFRSF21 ADGRG6 HRH2 ESPL1	9.91e-05	175	117	5	fa16c6ba08dc0cc22e8cf049db0577811d080df6
Drug	Pivampicillin [33817-20-8]; Up 200; 8.6uM; PC3; HT_HG-U133A	FN1 CACNA2D2 NPHP4 SCN4A AIG1 LRP1 CACNA1I ALDH2	7.79e-06	197	116	8	5046_UP
Drug	Asbestos	NAT2 FN1 CACNA2D2 MYO7A SLC44A4 ADGRG6 IGF2BP3 HRH2	1.28e-05	211	116	8	ctd:D001194
Drug	pyraclofos	CACNA1D CACNA2D2 SCN4A SCNN1B CACNA1I LARGE1	1.73e-05	106	116	6	CID000093460
Drug	VRA-GlcNAc	ENGASE NAGLU	2.57e-05	2	116	2	CID006439204
Drug	5-apthp	ENGASE NAGLU	2.57e-05	2	116	2	CID003083389
Drug	a-ET	RAB3D HRH2 ALDH2 ALDH1B1	2.64e-05	34	116	4	CID000002039
Drug	lamotrigine	CACNA1D CACNA2D2 LOXL1 SCN4A SCNN1B CACNA1I	2.89e-05	116	116	6	CID000003878
Drug	Androgen Antagonists	CACNA1D RELN CACNA2D2 CYP19A1 CACNA1I	4.09e-05	75	116	5	ctd:D000726
Drug	N-bromoacetamide	NAT2 CYP19A1 SCN4A SCNN1B	4.13e-05	38	116	4	CID000004353
Drug	Tolbutamide [64-77-7]; Down 200; 14.8uM; PC3; HT_HG-U133A	CACNA2D2 PACS1 SMARCA2 LRP1 ADGRF5 ALDH1B1 GRAMD1C	5.84e-05	192	116	7	3804_DN
Drug	5-hydroxytryptophol	ENGASE NAGLU LOXL1 ALDH2	6.17e-05	42	116	4	CID000009061
Drug	Tolfenamic acid [13710-19-5]; Down 200; 15.2uM; HL60; HG-U133A	TRAF3 CNNM2 DDX31 FN1 TNFRSF21 TRMT2A SMARCA2	6.23e-05	194	116	7	1437_DN
Drug	Epicatechin-(-) [154-23-4]; Up 200; 13.8uM; MCF7; HT_HG-U133A	RELN CACNA2D2 SH3GL3 NAGLU PEX1 PACS1 RAB3B	6.65e-05	196	116	7	2815_UP
Drug	gentamicin	ENGASE CLTCL1 FN1 MYO7A NAGLU IDUA LRP1	7.09e-05	198	116	7	CID000003467
Drug	Trimethadione [127-48-0]; Up 200; 28uM; HL60; HT_HG-U133A	RELN FN1 CACNA2D2 RAB3D LRRK1 PTPRM AIG1	7.09e-05	198	116	7	2486_UP
Drug	Tridihexethyl chloride; Up 200; 11.4uM; PC3; HT_HG-U133A	MYO7A ABCC9 SLC5A2 MEGF8 SCN4A LRP1 GRAMD1C	7.09e-05	198	116	7	5067_UP
Drug	Propoxycaine hydrochloride [550-83-4]; Up 200; 12uM; MCF7; HT_HG-U133A	FN1 NPHP4 PTPRM SCN4A SMARCA1 CACNA1I SAMD14	7.09e-05	198	116	7	3583_UP
Drug	Ronidazole [7681-76-7]; Up 200; 20uM; MCF7; HT_HG-U133A	RELN FN1 MYO7A NAGLU TRMT2A FOXO4 APOL2	7.09e-05	198	116	7	3557_UP
Drug	Ergocryptine-alpha [511-09-1]; Down 200; 7uM; HL60; HT_HG-U133A	FN1 MYO7A HRH2 FOXO4 CACNA1I ALDH1B1 NCKAP1L	7.32e-05	199	116	7	2572_DN
Drug	AC1NMNW3	ENGASE NAGLU	7.69e-05	3	116	2	CID005029013
Drug	MNP-Gal	ENGASE NAGLU	7.69e-05	3	116	2	CID004394515
Drug	2-(ethylthio)ethylamine	ENGASE NAGLU	7.69e-05	3	116	2	CID000148011
Drug	opposide	ENGASE NAGLU	7.69e-05	3	116	2	CID000209734
Drug	CNP-NAG	ENGASE NAGLU	7.69e-05	3	116	2	CID000128421
Drug	potassium tripolyphosphate	ENGASE NAGLU	7.69e-05	3	116	2	CID000061695
Drug	AC1NB2KI	ENGASE NAGLU	7.69e-05	3	116	2	CID004436564
Disease	estrone measurement	ADAM21 CYP19A1	1.52e-04	5	116	2	EFO_0007970
Disease	BMI-adjusted waist-hip ratio, forced expiratory volume	CYP19A1 ALDH2	2.27e-04	6	116	2	EFO_0004314, EFO_0007788
Disease	forced expiratory volume	CACNA1D CYP19A1 PIEZO1 SH3GL3 SLC44A4 ADGRG6 IGF2BP3 LOXL1 SCN4A SMARCA2 RMC1	2.87e-04	789	116	11	EFO_0004314
Disease	docosahexaenoic acid measurement, sex interaction measurement	PTPRM NHEJ1	3.18e-04	7	116	2	EFO_0007761, EFO_0008343
Disease	Vasodilators used in cardiac diseases use measurement	CNNM2 RNF213 ALDH2	3.24e-04	34	116	3	EFO_0009926
Disease	hypokalemic periodic paralysis (implicated_via_orthology)	SCN4A SCNN1B	4.22e-04	8	116	2	DOID:14452 (implicated_via_orthology)
Disease	Industrial Dermatosis	NAT2 ALDH2	4.22e-04	8	116	2	C0086457
Disease	Dermatitis, Occupational	NAT2 ALDH2	4.22e-04	8	116	2	C0028796
Disease	hemoglobin measurement, mean corpuscular hemoglobin concentration	PIEZO1 ALDH2	4.22e-04	8	116	2	EFO_0004509, EFO_0004528
Disease	epilepsy (implicated_via_orthology)	CACNA2D2 RAB3D SCN4A LRP1 RAB3B	4.74e-04	163	116	5	DOID:1826 (implicated_via_orthology)
Disease	sciatic neuropathy (biomarker_via_orthology)	CACNA1D ABCC9 LRP1 CACNA1I	6.40e-04	99	116	4	DOID:11446 (biomarker_via_orthology)
Disease	cerebral palsy (implicated_via_orthology)	AGAP5 AGAP1	6.75e-04	10	116	2	DOID:1969 (implicated_via_orthology)
Disease	quality of life during menstruation measurement, acne	FHOD3 SDK1	8.23e-04	11	116	2	EFO_0003894, EFO_0009366
Disease	Malignant mesothelioma	NAT2 FN1 IGF2BP3 SMARCA2	9.18e-04	109	116	4	C0345967
Disease	Ciliopathies	TMEM237 MYO7A NPHP4 SCNN1B	9.50e-04	110	116	4	C4277690
Disease	fructose measurement, glucose measurement, galactose measurement	TNFRSF21 DSCAML1	9.86e-04	12	116	2	EFO_0004468, EFO_0010477, EFO_0010481
Disease	pulse pressure measurement	CACNA1D CNNM2 IQCH FN1 RNF213 ABCC9 FHOD3 PIK3R4 OLFM3 MALRD1 MEGF8 LOXL1 AIG1 LRP1	1.14e-03	1392	116	14	EFO_0005763
Disease	Coffin-Siris syndrome	SMARCA1 SMARCA2	1.16e-03	13	116	2	C0265338
Disease	angina pectoris	CNNM2 RNF213 LOXL1 ALDH2	1.52e-03	125	116	4	EFO_0003913
Disease	Calcium channel blocker use measurement	CACNA1D NAT2 RNF213 SLC44A4 ALDH2	1.57e-03	213	116	5	EFO_0009930
Disease	gout, hyperuricemia	MALRD1 ALDH2	1.77e-03	16	116	2	EFO_0004274, EFO_0009104
Disease	Colorectal Carcinoma	FN1 CD109 ABCC5 ABCB6 SLC44A4 DSCAML1 SCNN1B LRP1 ALDH2	1.85e-03	702	116	9	C0009402
Disease	androstenedione measurement, estrone measurement	CYP19A1 PTPRM	2.25e-03	18	116	2	EFO_0007970, EFO_0007972
Disease	schizophrenia (implicated_via_orthology)	CACNA1D RELN CNNM2	2.46e-03	68	116	3	DOID:5419 (implicated_via_orthology)
Disease	Manic Disorder	CACNA1D RELN PACS1	2.79e-03	71	116	3	C0024713
Disease	gastric ulcer (biomarker_via_orthology)	IDUA FOXO4	3.06e-03	21	116	2	DOID:10808 (biomarker_via_orthology)
Disease	low density lipoprotein cholesterol measurement, phospholipids:total lipids ratio	CPNE2 NAT2 CD300LG ATG16L2	3.17e-03	153	116	4	EFO_0004611, EFO_0020946
Disease	otitis media (implicated_via_orthology)	NAGLU IDUA	3.36e-03	22	116	2	DOID:10754 (implicated_via_orthology)
Disease	vital capacity	IQCH FN1 CACNA2D2 CYP19A1 PIEZO1 ADGRG6 IGF2BP3 LOXL1 SMARCA2 ALDH2 RMC1 AGAP1	3.46e-03	1236	116	12	EFO_0004312
Disease	axial length measurement	LARGE2 CACNA1D CNNM2	3.50e-03	77	116	3	EFO_0005318
Disease	Manic	CACNA1D RELN PACS1	3.63e-03	78	116	3	C0338831
Disease	Depression, Bipolar	CACNA1D RELN PACS1	3.77e-03	79	116	3	C0005587

Protein segments in the cluster

Peptide	Gene	Start	Entry
VLTLVDNWYQVTQGI	APOL2	206	Q9BQE5
EFWQLLQQNYGTELG	GRAMD1C	186	Q8IYS0
NEYLSAIWAVGQIIQ	CPNE2	336	Q96FN4
LAATYNQAAQLWKVG	ATG16L2	396	Q8NAA4
YLLGEVLNNYIWDTQ	AIG1	211	Q9NVV5
NVVLAQLLIWYGVDV	AGAP1	781	Q9UPQ3
KQVQWTNVYEDALGL	CACNA2D2	481	Q9NY47
TYIILIGIEIWNQGN	ADAM21	251	Q9UKJ8
LVLWALLVYNATNNT	ADGRG6	476	Q86SQ4
QALQAGTVWVNTYNI	ALDH1B1	461	P30837
IQEAWIVQNAVVYVL	CFAP46	731	Q8IYW2
GQQVQFSLWVLRYVV	ABCB6	181	Q9NP58
VNTNVVLRYDGLITW	CHRNA9	131	Q9UGM1
YLNWVVRNLADLEVQ	ABCC9	1261	O60706
NYGNAAVWLSLIIGQ	DGAT1	451	O75907
QEAIWQRVYLALGLT	NAGLU	171	P54802
KTYSWDNAQVILVGN	RAB3B	121	P20337
KTYSWDNAQVILVGN	RAB3D	121	O95716
TLEQQVWATGLNLAY	IQCH	831	Q86VS3
IGLVENQSDWYLGNL	LARGE2	226	Q8N3Y3
YEGIFNTSLQWILEN	LEMD3	571	Q9Y2U8
VVELQAITYWGQTRL	ANOS1	371	P23352
GLDIQQLYWELSQLT	MUC16	14156	Q8WXI7
QLYWELSQLTHGVTQ	MUC16	14161	Q8WXI7
AQILRIQYAWANSEI	FIGNL1	36	Q6PIW4
VAAQWVEVQRGLVIY	DTD2	31	Q96FN9
FEEYVIVGLNWLQAV	KATNBL1	231	Q9H079
VLGLVENQSDWYLGN	LARGE1	266	O95461
SSINKWIQIEYLNIG	KLHL6	396	Q8WZ60
YLVSGGLNNTVNIWD	NEDD1	91	Q8NHV4
NYTAVAQTVNLLAEW	NELFCD	86	Q8IXH7
NQTIYWQEGLLVTFD	LRRK1	1081	Q38SD2
LSYIDELVWQGSLQN	ERVFC1-1	36	P60608
YVKQTWNLQGQALEQ	SYK	131	P43405
GNIYWVESNLDQIEV	LRP1	1356	Q07954
QLIQWENNGQVYSLL	LOXL1	41	Q08397
TKQAYWQIALDNIQV	CTSE	251	P14091
GDNVVLDQTYLWQGV	EIF2B5	386	Q13144
WGNQSYAELISQAIE	FOXO4	101	P98177
ELYWLATLQQQLGAG	NRL	71	P54845
NEVLEAIVLWLGYAN	HRH2	266	P25021
NQQLLEYQLATGTWV	MEGF8	1646	Q7Z7M0
IVWLAGYNATTQEIV	NCKAP1L	721	P55160
GLDLPQVTWIVQYNA	DDX31	591	Q9H8H2
VEYSIVIQQLSNGKW	DDOST	331	P39656
AEISSLQSVRQWYQQ	GOLGA3	566	Q08378
HLQWEVLDSLLVQYG	IGF2BP3	91	O00425
YDRQQLWKANVGFVI	IQGAP3	721	Q86VI3
YLAVQTLQIDVWDGD	NPHP4	741	O75161
VILVNTTDWQGQYVA	PACS1	566	Q6VY07
LQYSVNNGITWHVIA	RELN	3361	P78509
QETLIVWYEAENQGL	PPP4R3C	66	Q6ZMV5
VLYNQGKQWLEATIQ	MALRD1	766	Q5VYJ5
AYVAQQAWILNATLR	ABCC5	626	O15440
AQVYSAVLQGLWEEN	RGL4	16	Q8IZJ4
YLQSLEQIGVQDFWI	B3GNT5	206	Q9BYG0
GNTVQYWLLLDRIIQ	DAAM1	396	Q9Y4D1
LGDWSIQVQVNDQTY	CD109	201	Q6YHK3
LDYGENLVQKWQVLS	ESPL1	971	Q14674
SAIVVKIQGYFDAWQ	CYP19A1	211	P11511
NRGQQYLLWVAAVTS	DSCAML1	1256	Q8TD84
INQQWERTYLGNALV	FN1	61	P02751
GAINFDNIGYAWIVI	CACNA1I	336	Q9P0X4
DNIGYAWIVIFQVIT	CACNA1I	341	Q9P0X4
QILTQEDWNVVLYNG	CACNA1I	816	Q9P0X4
INRNETIQWLYTLIG	FHOD3	186	Q2V2M9
EILGYRVIQISQFEW	FASTKD1	806	Q53R41
LSWDQQLNLAYVGAV	IDUA	66	P35475
GWIVQKIFQAALYAA	GLTP	141	Q9NZD2
VNQLLYWALTTIGFQ	NAT2	71	P11245
AYQSVQETWLAALIV	SLC44A4	301	Q53GD3
GLVLWYDSVVQSGQL	ENGASE	266	Q8NFI3
IIWTQYEIQVAAYNG	SDK1	836	Q7Z5N4
ATQALTEWYILQATN	SCNN1B	211	P51168
AQWKSAVQGLLNYIN	IZUMO4	161	Q1ZYL8
VVWNGLEELNNAIKY	PEX1	386	O43933
AYVRNGWNLLDFVIV	CACNA1D	191	Q01668
GVQVLLQQWIEYIKA	CUL4B	486	Q13620
LWAVYATNQNAGNIV	OLFM3	356	Q96PB7
WIQAIGLREYANNIL	PPFIA2	1116	O75334
ASVGATYLWIQLNAN	PTPRM	291	P28827
TYLWIQLNANSINGD	PTPRM	296	P28827
AAEVLYTVIQDWAQL	TRMT2A	416	Q8IZ69
GQVRWLNVKVNYDNV	SCN4A	1216	P35499
QQTDEYVANLTNLVW	SMARCA2	531	P51531
LNWLISLYENGVNGI	SMARCA1	191	P28370
IITLTNQIDENWYEG	SH3GL3	311	Q99963
LVAAQVGSQWKDIYQ	TNFRSF21	421	O75509
EVYKAWVNQLETQTG	IQGAP2	1006	Q13576
VGQWLQSLNLEQYAA	SAMD14	331	Q8IZD0
KQGYALLVSDLQQVW	NHEJ1	31	Q9H9Q4
GENSFVLVQAEYNWI	REELD1	501	A0A1B0GV85
LGYTVFQWLGEQVQI	SLC28A2	221	O43868
WFAVYVELNQQIAAL	SESTD1	326	Q86VW0
TWFIVVAAIQDNRYI	ADGRF5	1066	Q8IZF2
ANYLSQALQAGTVWV	ALDH2	456	P05091
NVVLAQLLIWYGVDV	AGAP5	636	A6NIR3
IVTLWNLTLQDAGEY	CD300LG	91	Q6UXG3
YQKWLLLVGISAQQN	CLTCL1	161	P53675
VKLRVYGQNINNETW	CNNM2	101	Q9H8M5
VWNIVVIYVLAGDQL	TMEM237	241	Q96Q45
YQSWVIAAVQGNNEV	PIK3R4	1196	Q99570
ELWVQAQYITDAEGL	RNF213	3721	Q63HN8
FQVLETASYNGVLIW	TRAF3	406	Q13114
VSGSEDNLVYIWNLQ	WDR5B	271	Q86VZ2
SGAVFIQQALGWNIY	SLC5A2	161	P31639
IQQALGWNIYASVIA	SLC5A2	166	P31639
DIIISASQGYLWNLQ	RMC1	346	Q96DM3
IITLTNQIDENWYEG	SH3GL2	316	Q99962
RLQQEQGWAIGVVAY	PSTK	41	Q8IV42
WDIIAVNYNAIGVDR	FSBP	46	O95073
DAVWQTQNNALYGVL	UNC93A	361	Q86WB7
IVQAEEYLFQAQWTV	ZMYND12	146	Q9H0C1
LVWLQVIVANSYAAI	VN1R5	301	Q7Z5H4
NVLELIYAQTLVWIG	TMC5	776	Q6UXY8
AVAWTNLGVLYLTNE	TTC37	861	Q6PGP7
LAYQAWVTNAQAVLR	PIEZO1	1446	Q92508
AWYNVNVLTLIGINF	TSPAN19	206	P0C672
LQQVQLYDESVDWNG	XRRA1	271	Q6P2D8
WAGISLQISENENYV	ZNF285	111	Q96NJ3
WVKDGAVVQNLDQLY	TYRO3	76	Q06418
WNVDELQAYAQLVSL	TYW1B	516	Q6NUM6
NWQAVSVNYTAVGRI	ZAN	326	Q9Y493
KNDVIVAVNWTGVYF	MYO7A	1486	Q13402