Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	transmembrane transporter activity	CACNA1B ABCA13 SLCO2B1 TRPC6 SLC2A14 SLC44A2 PKD2L1 GRIA4 KCNK9 LETM1 SLC2A3 MFSD2A CATSPER1 KCNA4 KCNA7 SLC45A3 RALBP1 SLC39A5 ABCG5	8.44e-06	1180	103	19	GO:0022857
GeneOntologyMolecularFunction	xylose binding	SLC2A14 SLC2A3	2.64e-05	2	103	2	GO:0033222
GeneOntologyMolecularFunction	transporter activity	CACNA1B ABCA13 SLCO2B1 TRPC6 SLC2A14 SLC44A2 PKD2L1 GRIA4 KCNK9 LETM1 SLC2A3 MFSD2A CATSPER1 KCNA4 KCNA7 SLC45A3 RALBP1 SLC39A5 ABCG5	2.90e-05	1289	103	19	GO:0005215
GeneOntologyMolecularFunction	D-glucose binding	SLC2A14 SLC2A3 GYS2	4.66e-05	14	103	3	GO:0005536
GeneOntologyMolecularFunction	inorganic cation transmembrane transporter activity	CACNA1B TRPC6 PKD2L1 GRIA4 KCNK9 LETM1 MFSD2A CATSPER1 KCNA4 KCNA7 SLC45A3 SLC39A5	9.34e-05	627	103	12	GO:0022890
GeneOntologyMolecularFunction	metal ion transmembrane transporter activity	CACNA1B TRPC6 PKD2L1 KCNK9 LETM1 MFSD2A CATSPER1 KCNA4 KCNA7 SLC39A5	1.45e-04	465	103	10	GO:0046873
GeneOntologyMolecularFunction	galactose transmembrane transporter activity	SLC2A14 SLC2A3	3.90e-04	6	103	2	GO:0005354
GeneOntologyMolecularFunction	sugar transmembrane transporter activity	SLC2A14 SLC2A3 SLC45A3	4.42e-04	29	103	3	GO:0051119
GeneOntologyMolecularFunction	inorganic molecular entity transmembrane transporter activity	CACNA1B TRPC6 PKD2L1 GRIA4 KCNK9 LETM1 MFSD2A CATSPER1 KCNA4 KCNA7 SLC45A3 SLC39A5	5.31e-04	758	103	12	GO:0015318
GeneOntologyMolecularFunction	monoatomic cation transmembrane transporter activity	CACNA1B TRPC6 PKD2L1 KCNK9 LETM1 MFSD2A CATSPER1 KCNA4 KCNA7 SLC45A3 SLC39A5	6.30e-04	664	103	11	GO:0008324
GeneOntologyMolecularFunction	dehydroascorbic acid transmembrane transporter activity	SLC2A14 SLC2A3	7.23e-04	8	103	2	GO:0033300
GeneOntologyMolecularFunction	monoatomic ion transmembrane transporter activity	CACNA1B TRPC6 PKD2L1 GRIA4 KCNK9 LETM1 MFSD2A CATSPER1 KCNA4 KCNA7 SLC45A3 SLC39A5	7.89e-04	793	103	12	GO:0015075
GeneOntologyMolecularFunction	active transmembrane transporter activity	ABCA13 SLCO2B1 SLC44A2 LETM1 MFSD2A SLC45A3 RALBP1 SLC39A5 ABCG5	8.10e-04	477	103	9	GO:0022804
GeneOntologyMolecularFunction	galactoside binding	SLC2A14 SLC2A3	9.26e-04	9	103	2	GO:0016936
GeneOntologyMolecularFunction	calcium ion transmembrane transporter activity	CACNA1B TRPC6 PKD2L1 LETM1 CATSPER1	1.12e-03	151	103	5	GO:0015085
GeneOntologyMolecularFunction	voltage-gated monoatomic cation channel activity	CACNA1B KCNK9 CATSPER1 KCNA4 KCNA7	1.15e-03	152	103	5	GO:0022843
GeneOntologyMolecularFunction	protein phosphatase 2A binding	CACNA1B ADCY8 PTPN1	1.32e-03	42	103	3	GO:0051721
GeneOntologyMolecularFunction	carbohydrate transmembrane transporter activity	SLC2A14 SLC2A3 SLC45A3	1.32e-03	42	103	3	GO:0015144
GeneOntologyMolecularFunction	monosaccharide binding	SLC2A14 COLEC10 SLC2A3 GYS2	1.48e-03	95	103	4	GO:0048029
GeneOntologyMolecularFunction	gated channel activity	CACNA1B PKD2L1 GRIA4 KCNK9 CATSPER1 KCNA4 KCNA7	1.73e-03	334	103	7	GO:0022836
GeneOntologyMolecularFunction	profilin binding	CYFIP1 FMNL1	1.98e-03	13	103	2	GO:0005522
GeneOntologyMolecularFunction	monoatomic cation channel activity	CACNA1B TRPC6 PKD2L1 KCNK9 CATSPER1 KCNA4 KCNA7	2.01e-03	343	103	7	GO:0005261
GeneOntologyMolecularFunction	ABC-type transporter activity	ABCA13 RALBP1 ABCG5	2.07e-03	49	103	3	GO:0140359
GeneOntologyMolecularFunction	voltage-gated monoatomic ion channel activity	CACNA1B KCNK9 CATSPER1 KCNA4 KCNA7	2.54e-03	182	103	5	GO:0005244
GeneOntologyMolecularFunction	monoatomic ion channel activity	CACNA1B TRPC6 PKD2L1 GRIA4 KCNK9 CATSPER1 KCNA4 KCNA7	2.60e-03	459	103	8	GO:0005216
GeneOntologyMolecularFunction	voltage-gated channel activity	CACNA1B KCNK9 CATSPER1 KCNA4 KCNA7	2.66e-03	184	103	5	GO:0022832
Domain	Glc_transpt_3	SLC2A14 SLC2A3	3.07e-05	2	104	2	IPR002945
Domain	RecA_monomer-monomer_interface	RAD51 MYO18A	9.18e-05	3	104	2	IPR020587
Domain	Channel_four-helix_dom	CACNA1B CATSPER1 KCNA4 KCNA7	2.86e-04	57	104	4	IPR027359
Domain	-	CACNA1B CATSPER1 KCNA4 KCNA7	2.86e-04	57	104	4	1.20.120.350
Domain	Ion_trans_dom	CACNA1B TRPC6 CATSPER1 KCNA4 KCNA7	4.41e-04	114	104	5	IPR005821
Domain	Ion_trans	CACNA1B TRPC6 CATSPER1 KCNA4 KCNA7	4.41e-04	114	104	5	PF00520
Domain	BIR	NAIP BIRC6	8.41e-04	8	104	2	SM00238
Domain	K_chnl_volt-dep_Kv1	KCNA4 KCNA7	8.41e-04	8	104	2	IPR003972
Domain	-	NAIP BIRC6	8.41e-04	8	104	2	1.10.1170.10
Domain	BIR	NAIP BIRC6	8.41e-04	8	104	2	PF00653
Domain	BIR_REPEAT_2	NAIP BIRC6	8.41e-04	8	104	2	PS50143
Domain	BIR_rpt	NAIP BIRC6	8.41e-04	8	104	2	IPR001370
Domain	BIR_REPEAT_1	NAIP BIRC6	8.41e-04	8	104	2	PS01282
Domain	MFS_dom	SLCO2B1 SLC2A14 SLC2A3 MFSD2A SLC45A3	9.19e-04	134	104	5	IPR020846
Pubmed	Recurrent moderate hypoglycemia accelerates the progression of Alzheimer's disease through impairment of the TRPC6/GLUT3 pathway.	TRPC6 SLC2A14 SLC2A3	2.67e-08	3	105	3	35077394
Pubmed	Patterned expression of ion channel genes in mouse dorsal raphe nucleus determined with the Allen Mouse Brain Atlas.	CACNA1B GRIA4 KCNK9 KCNA4	7.96e-07	24	105	4	22534482
Pubmed	KAP1 facilitates reinstatement of heterochromatin after DNA replication.	STAG1 NELFB SMC4 VPS16 TRRAP BIRC6 CBS PTPN1 CYFIP1 PRIM2 GCN1 CDK4	1.51e-06	704	105	12	29955894
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	RAD51 MGAT4B KALRN TRRAP BIRC6 BMP4 CELSR1 CELSR2 SLC45A3 NBEAL2 GCN1 ANKRD33B PLXNA1 FOXK1	6.14e-06	1105	105	14	35748872
Pubmed	Reprogramming- and pluripotency-associated membrane proteins in mouse stem cells revealed by label-free quantitative proteomics.	SLC2A14 SLC2A3	9.03e-06	2	105	2	23615220
Pubmed	Sex-specific association of sequence variants in CBS and MTRR with risk for promoter hypermethylation in the lung epithelium of smokers.	CBS MTRR	9.03e-06	2	105	2	22665368
Pubmed	Hypermethylated DNA as potential biomarkers for gastric cancer diagnosis.	CYP26B1 KCNA4	9.03e-06	2	105	2	21945024
Pubmed	Copy-Number Variation of the Glucose Transporter Gene SLC2A3 and Congenital Heart Defects in the 22q11.2 Deletion Syndrome.	SLC2A14 SLC2A3	9.03e-06	2	105	2	25892112
Pubmed	CD205+ polymorphonuclear myeloid-derived suppressor cells suppress antitumor immunity by overexpressing GLUT3.	SLC2A14 SLC2A3	9.03e-06	2	105	2	33368883
Pubmed	Neuronal functions, feeding behavior, and energy balance in Slc2a3+/- mice.	SLC2A14 SLC2A3	9.03e-06	2	105	2	18780771
Pubmed	Drosophila ATP6AP2/VhaPRR functions both as a novel planar cell polarity core protein and a regulator of endosomal trafficking.	CELSR1 CELSR2	9.03e-06	2	105	2	23292348
Pubmed	Expression of mouse-GLUT3 and human-GLUT3 glucose transporter proteins in brain.	SLC2A14 SLC2A3	9.03e-06	2	105	2	1734877
Pubmed	Sevoflurane Induces Learning and Memory Impairment in Young Mice Through a Reduction in Neuronal Glucose Transporter 3.	SLC2A14 SLC2A3	9.03e-06	2	105	2	31884568
Pubmed	Temporal and spatial distribution of murine placental and brain GLUT3-luciferase transgene as a readout of in vivo transcription.	SLC2A14 SLC2A3	9.03e-06	2	105	2	23193055
Pubmed	Gene expression of GLUT3 glucose transporter regulated by glucose in vivo in mouse brain and in vitro in neuronal cell cultures from rat embryos.	SLC2A14 SLC2A3	9.03e-06	2	105	2	8198523
Pubmed	Altered lactate metabolism in Huntington's disease is dependent on GLUT3 expression.	SLC2A14 SLC2A3	9.03e-06	2	105	2	29582588
Pubmed	Placental glucose and amino acid transport in calorie-restricted wild-type and Glut3 null heterozygous mice.	SLC2A14 SLC2A3	9.03e-06	2	105	2	22700768
Pubmed	Glucose transporter isoform-3-null heterozygous mutation causes sexually dimorphic adiposity with insulin resistance.	SLC2A14 SLC2A3	9.03e-06	2	105	2	18445753
Pubmed	Sex-Specific Life Course Changes in the Neuro-Metabolic Phenotype of Glut3 Null Heterozygous Mice: Ketogenic Diet Ameliorates Electroencephalographic Seizures and Improves Sociability.	SLC2A14 SLC2A3	9.03e-06	2	105	2	28324109
Pubmed	Expression of the brain-type glucose transporter is restricted to brain and neuronal cells in mice.	SLC2A14 SLC2A3	9.03e-06	2	105	2	1516757
Pubmed	Glucose Transporter 3 Potentiates Degranulation and Is Required for Platelet Activation.	SLC2A14 SLC2A3	9.03e-06	2	105	2	28663252
Pubmed	Neuronal glucose transporter isoform 3 deficient mice demonstrate features of autism spectrum disorders.	SLC2A14 SLC2A3	9.03e-06	2	105	2	19506559
Pubmed	Paternal age effects on sperm FOXK1 and KCNA7 methylation and transmission into the next generation.	KCNA7 FOXK1	9.03e-06	2	105	2	28171595
Pubmed	Canine brain glucose transporter 3: gene sequence, phylogenetic comparisons and analysis of functional sites.	SLC2A14 SLC2A3	9.03e-06	2	105	2	8654954
Pubmed	Single nucleotide polymorphisms in the NER pathway and clinical outcome of patients with bone malignant tumors.	ERCC5 MMS19	9.03e-06	2	105	2	23679317
Pubmed	Adult glut3 homozygous null mice survive to demonstrate neural excitability and altered neurobehavioral responses reminiscent of neurodevelopmental disorders.	SLC2A14 SLC2A3	9.03e-06	2	105	2	33482226
Pubmed	Deletion of ADAM-9 in HGF/CDK4 mice impairs melanoma development and metastasis.	ADAM9 CDK4	9.03e-06	2	105	2	28553955
Pubmed	Glucose Transporter 3 is Essential for the Survival of Breast Cancer Cells in the Brain.	SLC2A14 SLC2A3	9.03e-06	2	105	2	31817208
Pubmed	Brain glucose transporter (Glut3) haploinsufficiency does not impair mouse brain glucose uptake.	SLC2A14 SLC2A3	9.03e-06	2	105	2	21316350
Pubmed	Predictive impact of common variations in DNA repair genes on clinical outcome of osteosarcoma.	ERCC5 MMS19	9.03e-06	2	105	2	23886164
Pubmed	A candidate gene study of folate-associated one carbon metabolism genes and colorectal cancer risk.	CUBN CBS MTRR	1.18e-05	15	105	3	20615890
Pubmed	NFκB up-regulation of glucose transporter 3 is essential for hyperactive mammalian target of rapamycin-induced aerobic glycolysis and tumor growth.	SLC2A14 SLC2A3	2.70e-05	3	105	2	25578782
Pubmed	Glucose transporter GLUT3: ontogeny, targeting, and role in the mouse blastocyst.	SLC2A14 SLC2A3	2.70e-05	3	105	2	9108057
Pubmed	Polymorphisms in the CBS gene and homocysteine, folate and vitamin B12 levels: association with polymorphisms in the MTHFR and MTRR genes in Brazilian children.	CBS MTRR	2.70e-05	3	105	2	18792976
Pubmed	Significant reduction of the GLUT3 level, but not GLUT1 level, was observed in the brain tissues of several scrapie experimental animals and scrapie-infected cell lines.	SLC2A14 SLC2A3	2.70e-05	3	105	2	24243341
Pubmed	Spatiotemporal regulation of c-Fos by ERK5 and the E3 ubiquitin ligase UBR1, and its biological role.	UBR1 MAPK7	2.70e-05	3	105	2	17018293
Pubmed	Glucose transporter expression in brain. cDNA sequence of mouse GLUT3, the brain facilitative glucose transporter isoform, and identification of sites of expression by in situ hybridization.	SLC2A14 SLC2A3	2.70e-05	3	105	2	1730609
Pubmed	Glucose transporter isoform-3 mutations cause early pregnancy loss and fetal growth restriction.	SLC2A14 SLC2A3	2.70e-05	3	105	2	17213475
Pubmed	Gestational changes of glucose transporter gene expression in the mouse placenta and decidua.	SLC2A14 SLC2A3	2.70e-05	3	105	2	8905482
Pubmed	Regular Exercise Enhances Cognitive Function and Intracephalic GLUT Expression in Alzheimer's Disease Model Mice.	SLC2A14 SLC2A3	2.70e-05	3	105	2	31561359
Pubmed	High NOV/CCN3 expression during high-fat diet pregnancy in mice affects GLUT3 expression and the mTOR pathway.	SLC2A14 SLC2A3	2.70e-05	3	105	2	33586490
Pubmed	Hyperglycemia reduces mitochondrial content and glucose transporter expression in mouse embryos developing in vitro.	SLC2A14 SLC2A3	2.70e-05	3	105	2	19550108
Pubmed	The flamingo-related mouse Celsr family (Celsr1-3) genes exhibit distinct patterns of expression during embryonic development.	CELSR1 CELSR2	2.70e-05	3	105	2	11677057
Pubmed	Placental glucose transporter expression is regulated by glucocorticoids.	SLC2A14 SLC2A3	2.70e-05	3	105	2	10199793
Pubmed	Glucose transporter proteins in brain.	SLC2A14 SLC2A3	2.70e-05	3	105	2	7926364
Pubmed	Lack of association between genetic polymorphisms in enzymes associated with folate metabolism and unexplained reduced sperm counts.	CBS MTRR	2.70e-05	3	105	2	19657388
Pubmed	Molecular cloning of murine homologue dentatorubral-pallidoluysian atrophy (DRPLA) cDNA: strong conservation of a polymorphic CAG repeat in the murine gene.	SLC2A14 SLC2A3	2.70e-05	3	105	2	9070948
Pubmed	Glucose Metabolism Is Required for Platelet Hyperactivation in a Murine Model of Type 1 Diabetes.	SLC2A14 SLC2A3	2.70e-05	3	105	2	30765335
Pubmed	Evidence for a family of human glucose transporter-like proteins. Sequence and gene localization of a protein expressed in fetal skeletal muscle and other tissues.	SLC2A14 SLC2A3	2.70e-05	3	105	2	3170580
Pubmed	Calpain I Activation Causes GLUT3 Proteolysis and Downregulation of O-GlcNAcylation in Alzheimer's Disease Brain.	SLC2A14 SLC2A3	2.70e-05	3	105	2	29614685
Pubmed	Prevalence and effects of gene-gene and gene-nutrient interactions on serum folate and serum total homocysteine concentrations in the United States: findings from the third National Health and Nutrition Examination Survey DNA Bank.	CBS MTRR	2.70e-05	3	105	2	18614746
Pubmed	Polymorphisms in MTHFR, MS and CBS genes and premature acute myocardial infarction in a Pakistani population.	CBS MTRR	2.70e-05	3	105	2	28375104
Pubmed	LPCAT1 Facilitates Keratinocyte Hyperproliferation and Skin Inflammation in Psoriasis by Regulating GLUT3.	SLC2A14 SLC2A3	2.70e-05	3	105	2	38246582
Pubmed	Polymorphisms in the folate-metabolizing genes MTR, MTRR, and CBS and breast cancer risk.	CBS MTRR	2.70e-05	3	105	2	22236648
Pubmed	Nitrite reductase activity and inhibition of H₂S biogenesis by human cystathionine ß-synthase.	CBS MTRR	2.70e-05	3	105	2	24416422
Pubmed	High incidence of MTHFR, CBS, and MTRR polymorphisms in vitiligo patients. Preliminary report in a retrospective study.	CBS MTRR	2.70e-05	3	105	2	30720153
Pubmed	Vitamin C enters mouse T cells as dehydroascorbic acid in vitro and does not recapitulate in vivo vitamin C effects.	SLC2A14 SLC2A3	2.70e-05	3	105	2	19327547
Pubmed	Deletion of GLUT1 and GLUT3 Reveals Multiple Roles for Glucose Metabolism in Platelet and Megakaryocyte Function.	SLC2A14 SLC2A3	2.70e-05	3	105	2	28746873
Pubmed	The imprinted Phlda2 gene regulates extraembryonic energy stores.	SLC2A14 SLC2A3 GYS2	3.95e-05	22	105	3	19884348
Pubmed	A multi-factor trafficking site on the spliceosome remodeling enzyme BRR2 recruits C9ORF78 to regulate alternative splicing.	NELFB SMC4 LRRC40 VPS16 TUBGCP2 LETM1 UBE4A CYFIP1 MMS19	5.21e-05	560	105	9	35241646
Pubmed	Difference in allelic expression of genes probably associated with tumor progression in murine fibrosarcomas and cell lines.	SLC2A14 SLC2A3	5.40e-05	4	105	2	7961103
Pubmed	Relationship between polymorphisms in genes involved in homocysteine metabolism and maternal risk for Down syndrome in Brazil.	CBS MTRR	5.40e-05	4	105	2	15889417
Pubmed	IAPs: more than just inhibitors of apoptosis proteins.	NAIP BIRC6	5.40e-05	4	105	2	18414036
Pubmed	5,10-Methylenetetrahydrofolate reductase gene variants and congenital anomalies: a HuGE review.	CBS MTRR	5.40e-05	4	105	2	10791559
Pubmed	A Nodal enhanced micropeptide NEMEP regulates glucose uptake during mesendoderm differentiation of embryonic stem cells.	SLC2A14 SLC2A3	5.40e-05	4	105	2	35810171
Pubmed	Tight junction-based epithelial microenvironment and cell proliferation.	CLDN22 CLDN24	5.40e-05	4	105	2	19029935
Pubmed	Genetic and nutritional factors contributing to hyperhomocysteinemia in young adults.	CBS MTRR	5.40e-05	4	105	2	12642343
Pubmed	Glucose utilization and glucose transporter proteins GLUT-1 and GLUT-3 in brains of diabetic (db/db) mice.	SLC2A14 SLC2A3	5.40e-05	4	105	2	9124334
Pubmed	Oxygen-regulated expression of GLUT-1, GLUT-3, and VEGF in the mouse blastocyst.	SLC2A14 SLC2A3	5.40e-05	4	105	2	15515055
Pubmed	Variation in folate pathway genes contributes to risk of congenital heart defects among individuals with Down syndrome.	CBS MTRR	5.40e-05	4	105	2	20718043
Pubmed	The adhesion GPCRs CELSR1-3 and LPHN3 engage G proteins via distinct activation mechanisms.	CELSR1 CELSR2	5.40e-05	4	105	2	37224017
Pubmed	Trans-activators regulating neuronal glucose transporter isoform-3 gene expression in mammalian neurons.	SLC2A14 SLC2A3	5.40e-05	4	105	2	15054091
Pubmed	Hypoxia regulation of facilitated glucose transporter-1 and glucose transporter-3 in mouse chondrocytes mediated by HIF-1alpha.	SLC2A14 SLC2A3	5.40e-05	4	105	2	17983831
Pubmed	Prenatal Exposure to Sodium Arsenite Alters Placental Glucose 1, 3, and 4 Transporters in Balb/c Mice.	SLC2A14 SLC2A3	5.40e-05	4	105	2	26339590
Pubmed	A CBS haplotype and a polymorphism at the MSR gene are associated with cardiovascular disease in a Spanish case-control study.	CBS MTRR	5.40e-05	4	105	2	17553479
Pubmed	Endotoxin-induced enhancement of glucose influx into murine peritoneal macrophages via GLUT1.	SLC2A14 SLC2A3	5.40e-05	4	105	2	8557327
Pubmed	GLUT3 promotes macrophage signaling and function via RAS-mediated endocytosis in atopic dermatitis and wound healing.	SLC2A14 SLC2A3	5.40e-05	4	105	2	37721853
Pubmed	Glucose uptake, utilization, and signaling in GLUT2-null islets.	SLC2A14 SLC2A3	5.40e-05	4	105	2	10969832
Pubmed	Immunohistochemical localization and quantification of glucose transporters in the mouse brain.	SLC2A14 SLC2A3	5.40e-05	4	105	2	11955709
Pubmed	Cytoprotective effects of hesperetin and hesperidin against amyloid β-induced impairment of glucose transport through downregulation of neuronal autophagy.	SLC2A14 SLC2A3	5.40e-05	4	105	2	22383310
Pubmed	Creb1-Mecp2-(m)CpG complex transactivates postnatal murine neuronal glucose transporter isoform 3 expression.	SLC2A14 SLC2A3	5.40e-05	4	105	2	23493374
Pubmed	Analysis of glucose metabolism by 18F-FDG-PET imaging and glucose transporter expression in a mouse model of intracerebral hemorrhage.	SLC2A14 SLC2A3	5.40e-05	4	105	2	34035344
Pubmed	Changes in Expression of Follicular Glucose Transporters May Be Involved in Ovarian Function Impairment during Diabetic Hyperglycemia.	SLC2A14 SLC2A3	5.40e-05	4	105	2	31882430
Pubmed	Maternal gene polymorphisms involved in folate metabolism as risk factors for Down syndrome offspring in Southern Brazil.	CBS MTRR	5.40e-05	4	105	2	21045269
Pubmed	B-vitamin intake, metabolic genes, and colorectal cancer risk (United States).	CBS MTRR	5.40e-05	4	105	2	12020105
Pubmed	Methyltetrahydrofolate reductase polymorphism influences onset of Huntington's disease.	CBS MTRR	5.40e-05	4	105	2	15354395
Pubmed	Neonatal hypothyroidism affects testicular glucose homeostasis through increased oxidative stress in prepubertal mice: effects on GLUT3, GLUT8 and Cx43.	SLC2A14 SLC2A3	5.40e-05	4	105	2	28471544
Pubmed	Glucose transporter expression and functional role of hexokinase in insulin biosynthesis in mouse beta TC3 cells.	SLC2A14 SLC2A3	5.40e-05	4	105	2	7653530
Pubmed	Maternal hyperglycemia alters glucose transport and utilization in mouse preimplantation embryos.	SLC2A14 SLC2A3	5.40e-05	4	105	2	9688872
Pubmed	Developmental regulation of genes mediating murine brain glucose uptake.	SLC2A14 SLC2A3	5.40e-05	4	105	2	10070152
Pubmed	In vitro analysis of the glucose-transport system in GLUT4-null skeletal muscle.	SLC2A14 SLC2A3	5.40e-05	4	105	2	10455018
Pubmed	Glucose transporter 3 is a rab11-dependent trafficking cargo and its transport to the cell surface is reduced in neurons of CAG140 Huntington's disease mice.	SLC2A14 SLC2A3	5.40e-05	4	105	2	25526803
Pubmed	Hypoxia inducible factor-1-dependent up-regulation of BMP4 mediates hypoxia-induced increase of TRPC expression in PASMCs.	TRPC6 BMP4	5.40e-05	4	105	2	25824146
Pubmed	Developmental expression profiles of Celsr (Flamingo) genes in the mouse.	CELSR1 CELSR2	5.40e-05	4	105	2	11850187
Pubmed	Developing Brain Glucose Transporters, Serotonin, Serotonin Transporter, and Oxytocin Receptor Expression in Response to Early-Life Hypocaloric and Hypercaloric Dietary, and Air Pollutant Exposures.	SLC2A14 SLC2A3	5.40e-05	4	105	2	33774619
Pubmed	IKK-Mediated Regulation of the COP9 Signalosome via Phosphorylation of CSN5.	TUBGCP2 CBS UBE4A PTPN1 CYFIP1 MMS19	5.86e-05	221	105	6	31950832
Pubmed	A striking organization of a large family of human neural cadherin-like cell adhesion genes.	PCDHGB3 PCDHB12 CELSR1 CELSR2	6.89e-05	72	105	4	10380929
Pubmed	Menin and Menin-Associated Proteins Coregulate Cancer Energy Metabolism.	STAG1 SMC4 TUBGCP2 TRRAP CBS SRRT FOXK1	8.19e-05	341	105	7	32971831
Pubmed	Phylogenetic analysis of the cadherin superfamily allows identification of six major subfamilies besides several solitary members.	PCDHGB3 PCDHB12 CELSR1 CELSR2	8.96e-05	77	105	4	10835267
Pubmed	Polymorphisms in genes involved in folate metabolism and colorectal neoplasia: a HuGE review.	CBS MTRR	8.97e-05	5	105	2	14977639
GeneFamily	Adhesion G protein-coupled receptors, subfamily C\|CELSR cadherins	CELSR1 CELSR2	5.36e-05	3	77	2	913
GeneFamily	Adhesion G protein-coupled receptors, subfamily C\|CELSR cadherins	CELSR1 CELSR2	5.36e-05	3	77	2	1189
GeneFamily	Ring finger proteins\|Baculoviral IAP repeat containing\|Caspase recruitment domain containing	NAIP BIRC6	4.93e-04	8	77	2	419
CoexpressionAtlas	DevelopingKidney_e12.5_renal vesicle_emap-27679_k-means-cluster#2_top-relative-expression-ranked_1000	DUSP9 MFSD2A CELSR1 CELSR2 ABCG5	1.15e-05	62	101	5	gudmap_developingKidney_e12.5_renal vesicle_1000_k2
CoexpressionAtlas	DevelopingKidney_e11.5_metaneph mesench_emap-3843_k-means-cluster#4_top-relative-expression-ranked_200	DUSP9 FFAR4 SLC45A3 ABCG5	4.70e-05	42	101	4	gudmap_developingKidney_e11.5_metaneph mesench_200_k4
ToppCell	LPS_only-Unknown-Endothelial\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	EFCAB5 ADAMTS19 CYP26B1 TRPC6 COLEC10 TMEM229B	3.20e-07	115	105	6	ad5298c2ad8bf94fa13c2e50b0799e929473ef59
ToppCell	LPS_only-Unknown\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	EFCAB5 ADAMTS19 CYP26B1 TRPC6 COLEC10 TMEM229B	3.20e-07	115	105	6	7a733f6987b40ec497a03734b79ed5355ad3a2fc
ToppCell	LPS_only-Unknown-Endothelial-Pericyte_2\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	EFCAB5 ADAMTS19 CYP26B1 TRPC6 COLEC10 TMEM229B	3.20e-07	115	105	6	c67145d3cd9243994a141749b426ff2a6dcc8d93
ToppCell	PND28-Immune-Immune_Myeloid-Monocytic-Macrophage-AM-AM_mature\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	TPBGL CUBN FFAR4 TMEM168 PNPLA7 CLEC16A	2.06e-06	158	105	6	6811dc4f101dfa9a9cc13d949760d43aa522bf3b
ToppCell	PND10-Endothelial-Endothelial_lymphatic-Lymphatic_EC-LEC\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	SLCO2B1 DUSP9 TPBGL CELSR1 CCM2L SLC45A3	2.56e-06	164	105	6	4cfc9f92e49f86d3639e018b35b6a60dc62f494a
ToppCell	PND10-Endothelial-Endothelial_lymphatic-Lymphatic_EC\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	SLCO2B1 DUSP9 TPBGL CELSR1 CCM2L SLC45A3	2.56e-06	164	105	6	7a8e5ef52a8fd2877d59ef0696af8a7af90bbed6
ToppCell	PND10-Endothelial-Endothelial_lymphatic-Lymphatic_EC-LEC-LEC_mature\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	SLCO2B1 DUSP9 TPBGL CELSR1 CCM2L SLC45A3	2.56e-06	164	105	6	5e5bd81414ea2d64f73cdef19a0a78c17bec8c18
ToppCell	PND10-Endothelial-Endothelial_lymphatic\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	SLCO2B1 DUSP9 TPBGL CELSR1 CCM2L SLC45A3	2.56e-06	164	105	6	f13b8d9b7f42193f333d9a77571a1dde6bbb48d8
ToppCell	Posterior_cortex-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)-Excitatory_Neuron.Slc17a7-Slc17a6.Tshz2_(Retrosplenial_cortex_(RSG)/Subiculum/Parasubiculum)--\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	ADAMTS19 ANKMY1 CATSPER1 ABCG5	5.04e-06	48	105	4	e96a608c2239f2ceb07d0a492289b24fabf190a1
ToppCell	Posterior_cortex-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)-Excitatory_Neuron.Slc17a7-Slc17a6.Tshz2_(Retrosplenial_cortex_(RSG)/Subiculum/Parasubiculum)-\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	ADAMTS19 ANKMY1 CATSPER1 ABCG5	5.04e-06	48	105	4	17cb229b199c49ec74d2230b1f8dbb0195b1bf01
ToppCell	Posterior_cortex-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)-Excitatory_Neuron.Slc17a7-Slc17a6.Tshz2_(Retrosplenial_cortex_(RSG)/Subiculum/Parasubiculum)\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	ADAMTS19 ANKMY1 CATSPER1 ABCG5	5.04e-06	48	105	4	c030dfb7c3289df7f34e91f31be6e9b47ca045f5
ToppCell	PND03-Immune-Immune_Myeloid-Monocytic-Macrophage-IM-IM_prolif\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	RAD51 P2RY12 SLCO2B1 GRIA4 TPBGL	3.76e-05	159	105	5	c0e55f25271f788c08fa4b95186501fc27b2ec39
ToppCell	PND28-Immune-Immune_Myeloid-Monocytic-Macrophage-AM\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	TPBGL CUBN TMEM168 PNPLA7 CLEC16A	4.11e-05	162	105	5	d712bc31840ad1523e3dbf884acbb428a8995001
ToppCell	facs-Marrow-T_cells-18m-Lymphocytic-late_pro_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RAD51 KALRN PHKA1 CELSR2 CLEC16A	4.48e-05	165	105	5	0edd56e8d14eaeced9882dd9206ea93e8f402e8d
ToppCell	facs-Marrow-T_cells-18m-Lymphocytic-late_pro-B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RAD51 KALRN PHKA1 CELSR2 CLEC16A	4.48e-05	165	105	5	fa3aadfff6fb1e7f142db333c60c2cba02b17e6c
ToppCell	Striatum-Neuronal-Inhibitory-iN2(Gad1Gad2)\|Striatum / BrainAtlas - Mouse McCarroll V32	CUBN KCNK9 GYS2 BAIAP2L2	4.68e-05	84	105	4	9417fffe0ba79f5851920258dcd0f6c09218be13
ToppCell	356C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_3\|CD8+_Cytotoxic_T-cell / Donor, Lineage, Cell class and subclass (all cells)	RAD51 PIGS MYO18A ZNF700 PLXNA1	5.61e-05	173	105	5	7e2149205e119cec4f5099c83c85d1e13470137a
ToppCell	5'-GW_trimst-1.5-LargeIntestine-Epithelial-mature_enterocytic-Enterocyte\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CUBN CELSR1 SLC39A5 BAIAP2L2 DGAT1	6.09e-05	176	105	5	24eedbbb406d788630bb16678cceef4492d3999c
ToppCell	PND10-Immune-Immune_Myeloid-Megakaryocyte/Platelet-Megakaryocyte/Platelet-Megakaryocyte/Platelet_mature\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	P2RY12 KALRN SLC2A3 NBEAL2 TTLL11	6.43e-05	178	105	5	9e1f2596fcea5b79cc50b58d83706bb8605e224f
ToppCell	PND10-Immune-Immune_Myeloid-Megakaryocyte/Platelet-Megakaryocyte/Platelet\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	P2RY12 KALRN SLC2A3 NBEAL2 TTLL11	6.43e-05	178	105	5	aa659bd283c4dfbe292cd8698bbf6b1999ca3314
ToppCell	PND10-Immune-Immune_Myeloid-Megakaryocyte/Platelet\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	P2RY12 KALRN SLC2A3 NBEAL2 TTLL11	6.43e-05	178	105	5	bf1d273802a4f42e52ea1bd2a0cae2039559c093
ToppCell	E18.5-Immune-Immune_Myeloid-Megakaryocyte/Platelet\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	P2RY12 KALRN SLC2A3 NBEAL2 TTLL11	6.77e-05	180	105	5	ca2a35bfb67347e47f511589a3d0f763e6664634
ToppCell	E18.5-Immune-Immune_Myeloid-Megakaryocyte/Platelet-Megakaryocyte/Platelet-Megakaryocyte/Platelet_mature\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	P2RY12 KALRN SLC2A3 NBEAL2 TTLL11	6.77e-05	180	105	5	4e9e8cde2919610c4ac0025b1c9819808048bc1d
ToppCell	E18.5-Immune-Immune_Myeloid-Megakaryocyte/Platelet-Megakaryocyte/Platelet\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	P2RY12 KALRN SLC2A3 NBEAL2 TTLL11	6.77e-05	180	105	5	466381bf93c3da6a2a241daadb68e9aad2964eae
ToppCell	facs-Marrow-KLS-3m-Lymphocytic-late_pro-B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RAD51 CFAP73 MFSD2A TTLL11 PLXNA1	6.95e-05	181	105	5	145fae2746c5212640b7b11b04a7759ba8e5c322
ToppCell	droplet-Lung-1m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell-pulmonary_artery_endothelial_cell_l25\|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CYP26B1 KALRN CBS BMP4 ARMCX6	6.95e-05	181	105	5	136b0c60680068838d184d32aa99d7bea8718dbc
ToppCell	facs-Marrow-KLS-3m-Lymphocytic-late_pro_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RAD51 CFAP73 MFSD2A TTLL11 PLXNA1	6.95e-05	181	105	5	a9f1fc5973cffdbeb7d1f5c41534422d85d596ff
ToppCell	droplet-Limb_Muscle-Pre-Sort-18m-Macroglial-nan\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	P2RY12 GRIA4 MFSD2A CELSR1 CELSR2	7.14e-05	182	105	5	c00e503f442d44fbae73c5e2dc85be69e294e67a
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ABCA13 CLDN22 COLEC10 CELSR1 ANKRD33B	8.32e-05	188	105	5	63a4b25a0a6e05f80f1a6dd91b817f3cf49e6b68
ToppCell	MS-CD8-antiviral_CD4\|MS / Condition, Cell_class and T cell subcluster	NAIP TMX2 PRIM2 ZNF700 ZNF738	8.74e-05	190	105	5	8c831c4560b8e70f92b4c15644fea39f7f7afcf2
ToppCell	facs-Brain_Myeloid-Cortex-3m-Myeloid-nan\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	P2RY12 SLCO2B1 SLC44A2 CYFIP1 GCN1	9.64e-05	194	105	5	50c5fc349533281a426bc7227a8ea9eca8d11985
ToppCell	3'-Broncho-tracheal-Immune_Myeloid-Myeloid_macrophage-lung_macrophage\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	P2RY12 SLCO2B1 ADAM9 NAIP CYFIP1	9.64e-05	194	105	5	48c37251518f96524807b5bd1bbc2820637666ad
ToppCell	10x_5'_v1-Non-neoplastic-Myeloid-TAM-MG-TAM-MG_pro-infl_II\|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	P2RY12 SLCO2B1 ADAM9 NAIP CYFIP1	9.64e-05	194	105	5	d4ca32232ff543ce2101c29af215de1ac0dfd511
ToppCell	3'-Broncho-tracheal-Immune_Myeloid-Myeloid_macrophage-lung_macrophage-Interstitial_macrophage_perivascular-Interstitial_macrophage_perivascular_L.1.2.1.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	P2RY12 SLCO2B1 ADAM9 NAIP CYFIP1	9.64e-05	194	105	5	7b6a34d1f8922b71dcc931421666c1822cec8345
ToppCell	facs-Brain_Myeloid-Cortex-3m\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	P2RY12 SLCO2B1 SLC44A2 CYFIP1 GCN1	9.64e-05	194	105	5	1662b110f84584e75150df0ac970e7df82f26e7e
ToppCell	3'-Broncho-tracheal-Immune_Myeloid-Myeloid_macrophage-lung_macrophage-Interstitial_macrophage_perivascular\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	P2RY12 SLCO2B1 ADAM9 NAIP CYFIP1	9.64e-05	194	105	5	435406ebe626c702f7d5a99a3d68ee85aa09be95
ToppCell	facs-Brain_Myeloid-Cortex-3m-Myeloid\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	P2RY12 SLCO2B1 SLC44A2 CYFIP1 GCN1	9.64e-05	194	105	5	b31d6361fa939a92a4a3dc63c209ecd3eb514e6a
ToppCell	10x_5'_v1-Non-neoplastic-Myeloid-TAM-MG-TAM-MG_pro-infl_II-Z\|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	P2RY12 SLCO2B1 ADAM9 NAIP CYFIP1	9.64e-05	194	105	5	4cdd59b1dbeeae1c5cec11397b0eeea917c798fe
ToppCell	Bronchus_Control_(B.)-Immune-TX-TRAM-1\|Bronchus_Control_(B.) / Sample group, Lineage and Cell type	ERCC5 SLCO2B1 MYO18A PKD2L1 TTLL11	9.87e-05	195	105	5	dabf667875ed48fdce4f803f5ead39c71a6df42b
ToppCell	10x5'-GI_small-bowel-Myeloid_Mac-Erythrophagocytic_macrophages\|GI_small-bowel / Manually curated celltypes from each tissue	P2RY12 SLCO2B1 NAIP PKD2L1 CYFIP1	1.04e-04	197	105	5	be9879e3352b8c17e91ab1e2d1fb4c30ef6d8ce8
ToppCell	5'-Adult-SmallIntestine-Epithelial\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	OTC SLC39A5 ABCG5 BAIAP2L2 DGAT1	1.06e-04	198	105	5	8d629492d2199de8e036c19e9dacceb9c9e721a0
ToppCell	10x_5'_v1-Non-neoplastic-Myeloid-TAM-MG\|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	P2RY12 SLCO2B1 ADAM9 NAIP CYFIP1	1.06e-04	198	105	5	9aced8bdb56ee52866a0a9766a84336961bc4443
ToppCell	Tracheal-10x3prime_v2-Immune_Myeloid-Macrophage_other-Macro_AW_CX3CR1\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	SLCO2B1 NAIP MYO18A CBS FFAR4	1.09e-04	199	105	5	514dbf128b6832b1cbd65be023d4fe02400e8dec
ToppCell	5'-Adult-SmallIntestine\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	OTC SLC39A5 ABCG5 BAIAP2L2 DGAT1	1.09e-04	199	105	5	a5fffe381be1ba7d192b68d1d3937ce47663658e
ToppCell	3'-GW_trimst-1.5-SmallIntestine-Epithelial-mature_enterocytic\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CUBN OTC SLC39A5 BAIAP2L2 DGAT1	1.09e-04	199	105	5	a10768e1cddd2d38291c30d24820a94040a72211
ToppCell	3'-GW_trimst-1.5-SmallIntestine-Epithelial-mature_enterocytic-Enterocyte\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CUBN OTC SLC39A5 BAIAP2L2 DGAT1	1.09e-04	199	105	5	f26c20f5d7470e90eaa79613d0b87bd4865585a8
ToppCell	10x_5'_v1-Non-neoplastic-Myeloid-TAM-MG-TAM-MG_aging_sig\|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	RAD51 P2RY12 SLCO2B1 NAIP CYFIP1	1.11e-04	200	105	5	a1503bcc774bed9563eda7cf90b8b5bf4405ad85
ToppCell	mLN-Mast_cell-Mast\|mLN / Region, Cell class and subclass	PHKA1 MFSD2A CATSPER1 SLC45A3 PLXNA1	1.11e-04	200	105	5	81ea6e7a3940277751faf9097b30198159998c7b
ToppCell	10x_5'_v1-Non-neoplastic-Myeloid-TAM-MG-TAM-MG_aging_sig-Z\|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	RAD51 P2RY12 SLCO2B1 NAIP CYFIP1	1.11e-04	200	105	5	25247f8b6ba6cd899ba6bd47e28e090d697e4632
ToppCell	mLN-Mast_cell\|mLN / Region, Cell class and subclass	PHKA1 MFSD2A CATSPER1 SLC45A3 PLXNA1	1.11e-04	200	105	5	9a5f1d99d8d160923d4d0fbbf9ad48a26f8a4fad
ToppCell	Sigmoid-Dendritic_cell-cycling_DCs\|Dendritic_cell / Region, Cell class and subclass	SLCO2B1 ADAM9 SMC4 APPL2 CDK4	1.11e-04	200	105	5	372fe9018481a4e9ac6ab3af43705a48238c4376
ToppCell	mLN-(7)_Mast_cell-(70)_Mast\|mLN / shred on region, Cell_type, and subtype	PHKA1 MFSD2A CATSPER1 SLC45A3 PLXNA1	1.11e-04	200	105	5	a6c258cae678be581b1d85cf3446c65c34b13499
ToppCell	mLN-(7)_Mast_cell\|mLN / shred on region, Cell_type, and subtype	PHKA1 MFSD2A CATSPER1 SLC45A3 PLXNA1	1.11e-04	200	105	5	13bca944fbdbc0be6687eca82c62a4d231ab94f0
Disease	homocystinuria (is_implicated_in)	CBS MTRR	1.14e-05	2	100	2	DOID:9263 (is_implicated_in)
Disease	Cystathionine beta-Synthase Deficiency Disease	CBS MTRR	1.14e-05	2	100	2	C0751202
Disease	Homocystinuria	CBS MTRR	1.14e-05	2	100	2	C0019880
Disease	1-(1-enyl-stearoyl)-2-arachidonoyl-GPC (P-18:0/20:4) measurement	PKD2L1 TMEM229B	1.69e-04	6	100	2	EFO_0800394
Disease	melanoma	ERCC5 CUBN TRRAP TMEM132B CBS CDK4	2.05e-04	248	100	6	C0025202
Disease	pancreatic cancer (biomarker_via_orthology)	RAD51 CDK4	2.36e-04	7	100	2	DOID:1793 (biomarker_via_orthology)
Disease	Cutaneous Melanoma	ERCC5 TRRAP CDK4	3.67e-04	41	100	3	C0151779
Disease	glycogen storage disease (is_implicated_in)	PHKA1 GYS2	4.03e-04	9	100	2	DOID:2747 (is_implicated_in)
Disease	1-(1-enyl-palmitoyl)-2-palmitoleoyl-GPC (P-16:0/16:1) measurement	PKD2L1 TMEM229B	5.03e-04	10	100	2	EFO_0800464
Disease	Hyperhomocysteinemia	CBS MTRR	6.13e-04	11	100	2	C0598608
Disease	cataract (biomarker_via_orthology)	SLC2A14 SLC2A3	8.66e-04	13	100	2	DOID:83 (biomarker_via_orthology)
Disease	serum gamma-glutamyl transferase measurement	UBR1 STAG1 KALRN COLEC10 UBE4A CLDN24 CELSR2 NBEAL2 GYS2 GCN1	1.08e-03	914	100	10	EFO_0004532
Disease	Global developmental delay	CACNA1B TRRAP TMX2 BMP4	1.11e-03	133	100	4	C0557874
Disease	pancreatic adenocarcinoma (is_implicated_in)	RALBP1 CDK4	1.16e-03	15	100	2	DOID:4074 (is_implicated_in)
Disease	neurodegenerative disease (implicated_via_orthology)	UBR1 GRIA4 PNPLA7 CLEC16A	1.52e-03	145	100	4	DOID:1289 (implicated_via_orthology)
Disease	Microcephaly	TRRAP TMX2 MFSD2A	1.55e-03	67	100	3	C0025958
Disease	epilepsy (implicated_via_orthology)	CACNA1B KALRN KCNA4 KCNA7	2.33e-03	163	100	4	DOID:1826 (implicated_via_orthology)
Disease	breast cancer (implicated_via_orthology)	RAD51 CBS	3.24e-03	25	100	2	DOID:1612 (implicated_via_orthology)

Protein segments in the cluster

Peptide	Gene	Start	Entry
AFQEFLAGMRLIELL	NAIP	746	Q13075
VRMLNELFARFDRLA	ADCY8	436	P40145
ELRVSRILMFLSNGL	CLDN24	76	A6NM45
GFIRRLFLQLMLEDE	BIRC6	3806	Q9NR09
FLIQGFREMIRNLTQ	CATSPER1	431	Q8NEC5
IFLESLSRLNFLLRM	GYS2	341	P54840
GFLYVNTSQRMLRIL	ABCA13	1361	Q86UQ4
MNGFASLLRRNQFIL	COLEC10	1	Q9Y6Z7
FFQLDLLNGDLRAMV	CELSR1	1046	Q9NYQ6
SLMFRTRQADGVLLQ	CELSR2	1641	Q9HCU4
IQQFAMLLREYRLGL	CCM2L	431	Q9NUG4
LLLGRSRMAVLNLFQ	CFAP73	246	A6NFT4
RFLLRRILEMLFFTQ	DGAT1	276	O75907
RILEMLFFTQLQVGL	DGAT1	281	O75907
DFEATLLQMFGLRRR	BMP4	56	P12644
NNFRTFLQALMLLFR	CACNA1B	1636	Q00975
FMSLFIRNGNREILL	ARMCX6	281	Q7L4S7
LDLERRNAFGFTALM	ANKRD33B	181	A6NCL7
LLAMEQFLRRQIASE	RALBP1	496	Q15311
ARFLRMLLRLADEFG	RAD51	246	Q06609
ARRFILTILNMVFNL	ADAMTS19	346	Q8TE59
GAFLNLVVLRFLTMN	KCNK9	236	Q9NPC2
FFLELTMGRRIQFPI	CYFIP1	626	Q7L576
ADRQALSLLGRMLRF	MAPK7	316	Q13164
GLSQTRELQRFLFLM	OR4D2	16	P58180
FRMGLIQTADQLRFS	PTPN1	256	P18031
MRLRNGTFLTLLLFC	MGAT4B	1	Q9UQ53
LQFIGLNMAALLEAR	IBTK	896	Q9P2D0
QSSQRRTILEMLLGF	MMS19	406	Q96T76
LFAEMFRLRIGLIIQ	PHKA1	911	P46020
QKLTFRMAIRVLLGF	CYP26B1	186	Q9NR63
MRRFLLLYATQQGQA	MTRR	1	Q9UBK8
LRLARALLDGQELMF	IKBKE	426	Q14164
NNFLRFQLTMRLRSI	LETM1	341	O95202
FFGRARGMLQNRVLL	BAIAP2L2	201	Q6UXY1
MRIISRQIVLLFSGF	GRIA4	1	P48058
SQQDFRLFRTLFLLM	FFAR4	256	Q5NUL3
LGFVMDNVRSLLVLN	PLXNA1	1126	Q9UIW2
MLFNLRILLNNAAFR	OTC	1	P00480
LEEMSLRRGFFNLNR	MYO18A	36	Q92614
ALRGRMFVLNELVQT	KALRN	1926	O60229
FNFMGQLLDFERSLR	DUSP9	331	Q99956
DMVLQFLRTLFLRTR	NELFB	216	Q8WX92
FAGAFTLRQRMLNFV	TUBGCP2	676	Q9BSJ2
RDTMLQALRFVIQGA	GCN1	2401	Q92616
LNDTLRFGMFLQDLI	KLHL40	306	Q2TBA0
AGQRRMLFLFLLSLL	PCDHGB3	11	Q9Y5G1
ITNGLAMRIFFQIRS	P2RY12	41	Q9H244
RFGRRNSMLIVNLLA	SLC2A14	111	Q8TDB8
ALALVGVLILFMFRR	PNPLA7	21	Q6ZV29
GVLILFMFRRLRQFR	PNPLA7	26	Q6ZV29
IRQVLLFFVLLGMSQ	PCDHB12	11	Q9Y5F1
GNFLRINTIAMRLLA	PANK2	521	Q9BZ23
LGFRNEFQNLLLAIM	MFSD2A	336	Q8NA29
IQQEMDLLRFRFSIL	PRIM2	121	P49643
ELRVSRILMFLSNGL	CLDN22	76	Q8N7P3
EGRRITLMFNNLRLA	CUBN	2486	O60494
QRAGILFFRIMLLEL	EFCAB5	1321	A4FU69
RASMRELGLLIFFLF	KCNA7	306	Q96RP8
TIKDLMRQFLRGLDF	CDK4	116	P11802
RADNAFMLLTQARLF	BTBD1	176	Q9H0C5
MLQEFIINRLGRAFI	DNAH7	3396	Q8WXX0
AFTFARMLIAQEGLL	CBS	331	P35520
LARLEGREFEFLMRQ	FOXK1	106	P85037
MGLFLLFFVLRVRSN	ABCG5	396	Q9H222
MNTALRDGLLVFFFL	ADAM9	691	Q13443
RLLEYMGLQLRQAVF	ANKMY1	816	Q9P2S6
EDSLLQQMFIVRFLG	APPL2	486	Q8NEU8
LQALGLDFLELLMRF	FMNL1	741	O95466
NRFGRRNSMLIVNLL	SLC2A3	86	P11169
SARNAFFLLMRNIIR	SLC44A2	576	Q8IWA5
FGQMFVRLQLLRAVR	DALRD3	511	Q5D0E6
LFRRLTGQFCMIQTL	BVES	141	Q8NE79
RLQTINLSFNRFKML	LRRC40	496	Q9H9A6
MEVFLAQLRLLFGIA	PIGS	386	Q96S52
LFLLALMFLGLQRRQ	TAPBPL	416	Q9BX59
QSLLQTFIGRFRRIM	GINS3	136	Q9BRX5
MIDRGLQFEERNFLL	TMEM132B	971	Q14DG7
MEQFIIRNTLRLRFD	TMEM229B	131	Q8NBD8
ERNAVAAFLLMLRNF	NBEAL2	946	Q6ZNJ1
GQMFLESQELLRLFG	ERCC5	766	P28715
VQQMRRALFLGASAL	RNF215	141	Q9Y6U7
MLFRNRFLLLLALAA	PXYLP1	1	Q8TE99
LVFSLVMDRLVQRFG	SLC45A3	336	Q96JT2
DFAMLLQSGLSFRRL	SLC39A5	431	Q6ZMH5
ALQNRLRVFLSLMET	SRRT	216	Q9BXP5
FFLLRFLGQLSMDLE	LINC00477	76	Q96M19
AIRVFFMLRSLSLQL	CLEC16A	666	Q2KHT3
NTILFFRLDIRMGLL	TMX2	101	Q9Y320
INGLFSDDMLFLRQL	WDR47	41	O94967
LRLVDRMANLFIRFL	TTLL11	636	Q8NHH1
RKVMLENFRNLVFLG	ZNF738	61	Q8NE65
KNLFREVMLETFRNL	ZNF700	46	Q9H0M5
TLAVGIQFMFLRILA	SLCO2B1	596	O94956
LKNELNRGDFFMTLR	VPS16	581	Q9H269
MQRFSDLLQRLLNGI	CREBZF	156	Q9NS37
TERLRMQFLEGFRSF	UBR1	491	Q8IWV7
LRNNMFEISDRLIGI	SMC4	1251	Q9NTJ3
NGNLIRMLVLFFLES	STAG1	461	Q8WVM7
NLRSTGMLNAIQRFF	TMEM168	441	Q9H0V1
FRTLEVNRLMGKLLQ	PKD2L1	406	Q9P0L9
QLEFGSFLLSRMLLN	SLF1	951	Q9BQI6
IFLMVLYLNRRGIQR	TPBGL	321	P0DKB5
TIFLGLLVMNAADRF	TRPC6	451	Q9Y210
RFLNLLMNDAIFLLD	UBE4A	786	Q14139
QLLRAFTGRFLCNMT	TRRAP	1716	Q9Y4A5
LLFNTREFTLVRRLM	ZNF781	271	Q8N8C0
LRASMRELGLLIFFL	KCNA4	471	P22459