Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	microtubule motor activity	KIF23 KIF21A STARD9 DYNC1H1 KIF11	1.08e-04	70	134	5	GO:0003777
GeneOntologyMolecularFunction	tubulin binding	KIF23 CENPF KIF21A NF1 EML5 STARD9 DLEC1 TBCC TBCEL KIF11 HTT	1.50e-04	428	134	11	GO:0015631
GeneOntologyCellularComponent	phagophore	ATG2B ATG2A	1.24e-04	3	135	2	GO:0061908
GeneOntologyCellularComponent	mucus layer	MUC2 MUC5AC	1.24e-04	3	135	2	GO:0070701
GeneOntologyCellularComponent	laminin-5 complex	LAMA5 LAMB3	2.46e-04	4	135	2	GO:0005610
GeneOntologyCellularComponent	sarcoplasmic reticulum	CAMK2D CAMK2G CMYA5 RYR2 ITPR3	2.66e-04	88	135	5	GO:0016529
GeneOntologyCellularComponent	calcium- and calmodulin-dependent protein kinase complex	CAMK2D CAMK2G	4.09e-04	5	135	2	GO:0005954
GeneOntologyCellularComponent	sarcoplasm	CAMK2D CAMK2G CMYA5 RYR2 ITPR3	8.72e-04	114	135	5	GO:0016528
MousePheno	abnormal embryonic/fetal subventricular zone morphology	APAF1 ITGB8 WDFY3 DYNC1H1 HTT	1.14e-05	41	102	5	MP:0004274
Domain	ATG2	ATG2B ATG2A	4.96e-05	2	132	2	IPR026849
Domain	LYZL1/LYZL2	LYZL1 LYZL2	4.96e-05	2	132	2	IPR030057
Domain	ATG2_CAD	ATG2B ATG2A	4.96e-05	2	132	2	PF13329
Domain	ATG2_CAD_motif	ATG2B ATG2A	4.96e-05	2	132	2	IPR026885
Domain	C8	MUC2 MUC5AC OTOG	7.25e-05	12	132	3	PF08742
Domain	TIL	MUC2 MUC5AC OTOG	7.25e-05	12	132	3	PF01826
Domain	Unchr_dom_Cys-rich	MUC2 MUC5AC OTOG	9.37e-05	13	132	3	IPR014853
Domain	C8	MUC2 MUC5AC OTOG	9.37e-05	13	132	3	SM00832
Domain	TIL_dom	MUC2 MUC5AC OTOG	1.19e-04	14	132	3	IPR002919
Domain	BBOX	TRIM39 TRIM23 TRIM10 TRIM16 TRIM28	1.28e-04	69	132	5	SM00336
Domain	Interferon_reg_fac2-bd1_2_Znf	IRF2BP2 IRF2BPL	1.48e-04	3	132	2	IPR022750
Domain	IRF-2BP1_2	IRF2BP2 IRF2BPL	1.48e-04	3	132	2	PF11261
Domain	zf-B_box	TRIM39 TRIM23 TRIM10 TRIM16 TRIM28	1.56e-04	72	132	5	PF00643
Domain	VWF_type-D	MUC2 MUC5AC OTOG	1.81e-04	16	132	3	IPR001846
Domain	VWFD	MUC2 MUC5AC OTOG	1.81e-04	16	132	3	PS51233
Domain	VWD	MUC2 MUC5AC OTOG	1.81e-04	16	132	3	SM00216
Domain	VWD	MUC2 MUC5AC OTOG	1.81e-04	16	132	3	PF00094
Domain	Kinesin_motor_CS	KIF23 KIF21A STARD9 KIF11	1.97e-04	41	132	4	IPR019821
Domain	ZF_BBOX	TRIM39 TRIM23 TRIM10 TRIM16 TRIM28	2.57e-04	80	132	5	PS50119
Domain	-	KIF23 KIF21A STARD9 KIF11	2.60e-04	44	132	4	3.40.850.10
Domain	Kinesin	KIF23 KIF21A STARD9 KIF11	2.60e-04	44	132	4	PF00225
Domain	KISc	KIF23 KIF21A STARD9 KIF11	2.60e-04	44	132	4	SM00129
Domain	KINESIN_MOTOR_1	KIF23 KIF21A STARD9 KIF11	2.60e-04	44	132	4	PS00411
Domain	Kinesin_motor_dom	KIF23 KIF21A STARD9 KIF11	2.60e-04	44	132	4	IPR001752
Domain	KINESIN_MOTOR_2	KIF23 KIF21A STARD9 KIF11	2.60e-04	44	132	4	PS50067
Domain	Znf_B-box	TRIM39 TRIM23 TRIM10 TRIM16 TRIM28	2.72e-04	81	132	5	IPR000315
Domain	CaMKII_AD	CAMK2D CAMK2G	2.95e-04	4	132	2	PF08332
Domain	Ca/CaM-dep_prot_kinase-assoc	CAMK2D CAMK2G	2.95e-04	4	132	2	IPR013543
Domain	VWC_out	MUC2 MUC5AC OTOG	3.08e-04	19	132	3	SM00215
Domain	CT	MUC2 MUC5AC OTOG	4.82e-04	22	132	3	SM00041
Domain	Autophagy-rel_C	ATG2B ATG2A	4.89e-04	5	132	2	IPR015412
Domain	ATG_C	ATG2B ATG2A	4.89e-04	5	132	2	PF09333
Domain	EGF-like_CS	MATN3 LAMA5 LAMB3 ADAM29 ITGB8 STAB1 FBLN2 UMOD	5.41e-04	261	132	8	IPR013032
Domain	SPRY	TRIM39 CMYA5 RYR2 TRIM10 TRIM16	5.42e-04	94	132	5	PF00622
Domain	SPRY_dom	TRIM39 CMYA5 RYR2 TRIM10 TRIM16	5.42e-04	94	132	5	IPR003877
Domain	B30.2/SPRY	TRIM39 CMYA5 RYR2 TRIM10 TRIM16	5.69e-04	95	132	5	IPR001870
Domain	B302_SPRY	TRIM39 CMYA5 RYR2 TRIM10 TRIM16	5.69e-04	95	132	5	PS50188
Domain	EGF_2	MATN3 LAMA5 LAMB3 ADAM29 ITGB8 STAB1 FBLN2 UMOD	5.98e-04	265	132	8	PS01186
Domain	Cys_knot_C	MUC2 MUC5AC OTOG	7.08e-04	25	132	3	IPR006207
Domain	CTCK_2	MUC2 MUC5AC OTOG	7.08e-04	25	132	3	PS01225
Domain	RIH_assoc-dom	RYR2 ITPR3	7.30e-04	6	132	2	IPR013662
Domain	zf-RING_5	TRIM23 TRIM28	7.30e-04	6	132	2	PF14634
Domain	Ins145_P3_rec	RYR2 ITPR3	7.30e-04	6	132	2	PF08709
Domain	RIH_assoc	RYR2 ITPR3	7.30e-04	6	132	2	PF08454
Domain	RIH_dom	RYR2 ITPR3	7.30e-04	6	132	2	IPR000699
Domain	Ins145_P3_rcpt	RYR2 ITPR3	7.30e-04	6	132	2	IPR014821
Domain	Ryanodine_recept-rel	RYR2 ITPR3	7.30e-04	6	132	2	IPR015925
Domain	-	RYR2 ITPR3	7.30e-04	6	132	2	1.25.10.30
Domain	RYDR_ITPR	RYR2 ITPR3	7.30e-04	6	132	2	PF01365
Domain	WxxW_domain	MUC2 MUC5AC	7.30e-04	6	132	2	IPR025155
Domain	Mucin2_WxxW	MUC2 MUC5AC	7.30e-04	6	132	2	PF13330
Domain	ConA-like_dom	LAMA5 TRIM39 CMYA5 RYR2 TRIM10 TRIM16 WDFY3	9.46e-04	219	132	7	IPR013320
Domain	Glyco_hydro_22_lys	LYZL1 LYZL2	1.02e-03	7	132	2	IPR000974
Domain	Glyco_hydro_22_CS	LYZL1 LYZL2	1.02e-03	7	132	2	IPR019799
Domain	FYVE	MTMR4 ZFYVE26 WDFY3	1.10e-03	29	132	3	PF01363
Domain	FYVE	MTMR4 ZFYVE26 WDFY3	1.10e-03	29	132	3	SM00064
Domain	EGF_LAM_2	LAMA5 LAMB3 STAB1	1.22e-03	30	132	3	PS50027
Domain	EGF_LAM_1	LAMA5 LAMB3 STAB1	1.22e-03	30	132	3	PS01248
Domain	Chorein_N	ATG2B ATG2A	1.35e-03	8	132	2	PF12624
Domain	VPS13_N	ATG2B ATG2A	1.35e-03	8	132	2	IPR026854
Domain	Glyco_hydro_22	LYZL1 LYZL2	1.35e-03	8	132	2	IPR001916
Domain	LACTALBUMIN_LYSOZYME_2	LYZL1 LYZL2	1.35e-03	8	132	2	PS51348
Domain	Lys	LYZL1 LYZL2	1.35e-03	8	132	2	PF00062
Domain	LACTALBUMIN_LYSOZYME_1	LYZL1 LYZL2	1.35e-03	8	132	2	PS00128
Domain	LYZ1	LYZL1 LYZL2	1.35e-03	8	132	2	SM00263
Domain	-	TRIM39 TRIM10 TRIM16 TRIM28	1.61e-03	71	132	4	4.10.45.10
Domain	Znf_FYVE-rel	MTMR4 ZFYVE26 WDFY3	1.76e-03	34	132	3	IPR017455
Domain	EGF_Lam	LAMA5 LAMB3 STAB1	1.91e-03	35	132	3	SM00180
Domain	Laminin_EGF	LAMA5 LAMB3 STAB1	1.91e-03	35	132	3	PF00053
Domain	EGF-like_dom	MATN3 LAMA5 ADAM29 STAB1 FBLN2 UMOD OTOG	1.98e-03	249	132	7	IPR000742
Domain	MIR	RYR2 ITPR3	2.15e-03	10	132	2	PF02815
Domain	MIR_motif	RYR2 ITPR3	2.15e-03	10	132	2	IPR016093
Domain	MIR	RYR2 ITPR3	2.15e-03	10	132	2	PS50919
Domain	MIR	RYR2 ITPR3	2.15e-03	10	132	2	SM00472
Domain	Lysozyme-like_dom	LYZL1 LYZL2	2.15e-03	10	132	2	IPR023346
Domain	EGF_1	LAMA5 LAMB3 ADAM29 ITGB8 STAB1 FBLN2 UMOD	2.26e-03	255	132	7	PS00022
Domain	Znf_FYVE	MTMR4 ZFYVE26 WDFY3	2.43e-03	38	132	3	IPR000306
Domain	Laminin_EGF	LAMA5 LAMB3 STAB1	2.43e-03	38	132	3	IPR002049
Domain	GFP-like	STAB1 UMOD	2.62e-03	11	132	2	IPR023413
Domain	-	STAB1 UMOD	2.62e-03	11	132	2	2.40.155.10
Domain	ZF_FYVE	MTMR4 ZFYVE26 WDFY3	2.82e-03	40	132	3	PS50178
Domain	EGF_dom	STAB1 UMOD	3.12e-03	12	132	2	IPR024731
Domain	EGF_3	STAB1 UMOD	3.12e-03	12	132	2	PF12947
Domain	PRY	TRIM39 TRIM10 TRIM16	3.24e-03	42	132	3	PF13765
Domain	VWF_dom	MUC2 MUC5AC OTOG	3.24e-03	42	132	3	IPR001007
Domain	SPRY	TRIM39 RYR2 TRIM10 TRIM16	3.37e-03	87	132	4	SM00449
Domain	Kinesin-like_fam	KIF23 KIF21A KIF11	3.46e-03	43	132	3	IPR027640
Domain	-	CAMK2D CAMK2G	3.67e-03	13	132	2	3.10.450.50
Domain	Znf_C2H2-like	RAG1 ZNF484 ZNF559 ZNF652 ZFY ZNF385D ZBTB39 KLF10 ZNF667 SCAPER HELZ2 ZNF432 ZNF615	4.21e-03	796	132	13	IPR015880
Domain	PRY	TRIM39 TRIM10 TRIM16	4.73e-03	48	132	3	SM00589
Domain	PRY	TRIM39 TRIM10 TRIM16	4.73e-03	48	132	3	IPR006574
Domain	ZnF_C2H2	RAG1 ZNF484 ZNF559 ZNF652 ZFY ZNF385D ZBTB39 KLF10 ZNF667 SCAPER HELZ2 ZNF432 ZNF615	4.76e-03	808	132	13	SM00355
Domain	Bbox_C	TRIM23 TRIM28	4.90e-03	15	132	2	IPR003649
Domain	BBC	TRIM23 TRIM28	4.90e-03	15	132	2	SM00502
Domain	NTF2-like_dom	CAMK2D CAMK2G	4.90e-03	15	132	2	IPR032710
Domain	Growth_fac_rcpt_	MATN3 LAMA5 STAB1 FBLN2 UMOD	5.04e-03	156	132	5	IPR009030
Domain	Znf_RING/FYVE/PHD	RAG1 TRIM39 TRIM23 TRIM10 MTMR4 TRIM28 IRF2BPL ZFYVE26 WDFY3	5.36e-03	459	132	9	IPR013083
Domain	Laminin_N	LAMA5 LAMB3	5.58e-03	16	132	2	IPR008211
Domain	LamNT	LAMA5 LAMB3	5.58e-03	16	132	2	SM00136
Domain	LAMININ_NTER	LAMA5 LAMB3	5.58e-03	16	132	2	PS51117
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	KIF23 CTTNBP2 CENPF WDR7 CAMK2D CAMK2G KIF21A ADGRB2 MCC ZNFX1 NF1 EHMT2 TRIM28 WDFY3 RPA1 HOMER1 DYNC1H1 KIF11	4.44e-08	963	136	18	28671696
Pubmed	The tripartite motif family identifies cell compartments.	TRIM39 TRIM23 TRIM10 TRIM16 TRIM28	5.68e-07	41	136	5	11331580
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	SZT2 ADGRB2 LAMA5 LAMB3 ATG2A ITPR3 MICALL1 KLF10 ZBED4 TRIM28 KCNH2 HELZ2 PLA2G6 ZFYVE26 WDFY3 DYNC1H1 HTT	1.61e-06	1105	136	17	35748872
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	YPEL3 SUPT20H KIF21A HLCS FBXO11 ZNFX1 CMYA5 ITGB8 STAB1 UBA7 KANSL2 EHMT2 WDFY3 PIP4P2 TOP1 DYNC1H1 ZMYM5	1.17e-05	1285	136	17	35914814
Pubmed	All kinesin superfamily protein, KIF, genes in mouse and human.	KIF23 KIF21A STARD9 KIF11	1.34e-05	37	136	4	11416179
Pubmed	Hereditary spastic paraplegia with mental impairment and thin corpus callosum in Tunisia: SPG11, SPG15, and further genetic heterogeneity.	SPG11 ZFYVE26	1.52e-05	2	136	2	18332254
Pubmed	Cell-intrinsic glial pathology is conserved across human and murine models of Huntington's disease.	RAG1 HTT	1.52e-05	2	136	2	34233199
Pubmed	Atg2A/B deficiency switches cytoprotective autophagy to non-canonical caspase-8 activation and apoptosis.	ATG2B ATG2A	1.52e-05	2	136	2	28800131
Pubmed	Mammalian Atg2 proteins are essential for autophagosome formation and important for regulation of size and distribution of lipid droplets.	ATG2B ATG2A	1.52e-05	2	136	2	22219374
Pubmed	Neurofibromin interacts with the cytoplasmic Dynein Heavy Chain 1 in melanosomes of human melanocytes.	NF1 DYNC1H1	1.52e-05	2	136	2	23583712
Pubmed	Combined MET inhibition and topoisomerase I inhibition block cell growth of small cell lung cancer.	MET TOP1	1.52e-05	2	136	2	24327519
Pubmed	c-Met expression is regulated by Mitf in the melanocyte lineage.	MET MITF	1.52e-05	2	136	2	16455654
Pubmed	Adipocyte CAMK2 deficiency improves obesity-associated glucose intolerance.	CAMK2D CAMK2G	1.52e-05	2	136	2	34303021
Pubmed	Mucolytic activity of bacterial and human chitinases.	MUC2 MUC5AC	1.52e-05	2	136	2	17321686
Pubmed	Altered expression of MUC2 and MUC5AC in progression of colorectal carcinoma.	MUC2 MUC5AC	1.52e-05	2	136	2	20731025
Pubmed	Wide long lasting perinuclear Ca2+ release events generated by an interaction between ryanodine and IP3 receptors in canine Purkinje cells.	RYR2 ITPR3	1.52e-05	2	136	2	18586264
Pubmed	ATR prohibits replication catastrophe by preventing global exhaustion of RPA.	ATR RPA1	1.52e-05	2	136	2	24267891
Pubmed	Role of CaMKIIdelta phosphorylation of the cardiac ryanodine receptor in the force frequency relationship and heart failure.	CAMK2D RYR2	1.52e-05	2	136	2	20479242
Pubmed	CaM kinase II regulates cardiac hemoglobin expression through histone phosphorylation upon sympathetic activation.	CAMK2D CAMK2G	1.52e-05	2	136	2	31619570
Pubmed	Addiction-related genes in gambling disorders: new insights from parallel human and pre-clinical models.	DRD3 CAMK2D	1.52e-05	2	136	2	25266122
Pubmed	Ischemic Injury-Induced CaMKIIδ and CaMKIIγ Confer Neuroprotection Through the NF-κB Signaling Pathway.	CAMK2D CAMK2G	1.52e-05	2	136	2	29992531
Pubmed	Studies of mucus in mouse stomach, small intestine, and colon. II. Gastrointestinal mucus proteome reveals Muc2 and Muc5ac accompanied by a set of core proteins.	MUC2 MUC5AC	1.52e-05	2	136	2	23832517
Pubmed	Studies of mucus in mouse stomach, small intestine, and colon. III. Gastrointestinal Muc5ac and Muc2 mucin O-glycan patterns reveal a regiospecific distribution.	MUC2 MUC5AC	1.52e-05	2	136	2	23832516
Pubmed	Ca2+/calmodulin-dependent protein kinase II-γ (CaMKIIγ) negatively regulates vascular smooth muscle cell proliferation and vascular remodeling.	CAMK2D CAMK2G	1.52e-05	2	136	2	26567004
Pubmed	TRIM28 mediates chromatin modifications at the TCRα enhancer and regulates the development of T and natural killer T cells.	RAG1 TRIM28	1.52e-05	2	136	2	23169648
Pubmed	ZFYVE26/SPASTIZIN and SPG11/SPATACSIN mutations in hereditary spastic paraplegia types AR-SPG15 and AR-SPG11 have different effects on autophagy and endocytosis.	SPG11 ZFYVE26	1.52e-05	2	136	2	30081747
Pubmed	Integrin β8 Deletion Enhances Vascular Dysplasia and Hemorrhage in the Brain of Adult Alk1 Heterozygous Mice.	ACVRL1 ITGB8	1.52e-05	2	136	2	27352867
Pubmed	Cardiac CaM Kinase II genes δ and γ contribute to adverse remodeling but redundantly inhibit calcineurin-induced myocardial hypertrophy.	CAMK2D CAMK2G	1.52e-05	2	136	2	25124496
Pubmed	Vesl/Homer proteins regulate ryanodine receptor type 2 function and intracellular calcium signaling.	RYR2 HOMER1	1.52e-05	2	136	2	12887973
Pubmed	Role of defective calcium regulation in cardiorespiratory dysfunction in Huntington's disease.	RYR2 HTT	1.52e-05	2	136	2	32897880
Pubmed	Stabilizing cardiac ryanodine receptor prevents the development of cardiac dysfunction and lethal arrhythmia in Ca2+/calmodulin-dependent protein kinase IIδc transgenic mice.	CAMK2D RYR2	1.52e-05	2	136	2	32007269
Pubmed	In vitro analysis of the role of replication protein A (RPA) and RPA phosphorylation in ATR-mediated checkpoint signaling.	ATR RPA1	1.52e-05	2	136	2	22948311
Pubmed	Intestinal MUC2 and gastric M1/MUC5AC in preneoplastic lesions induced by 1,2-dimethylhydrazine in rat: a sequential analysis.	MUC2 MUC5AC	1.52e-05	2	136	2	17203232
Pubmed	ATR inhibitors VE-821 and VX-970 sensitize cancer cells to topoisomerase i inhibitors by disabling DNA replication initiation and fork elongation responses.	ATR TOP1	1.52e-05	2	136	2	25269479
Pubmed	[PI3K/Akt/Erk signaling pathway mediates neuroprotection of CaMKⅡγ and CaMKⅡδ against ischemic reperfusion injury in mice].	CAMK2D CAMK2G	1.52e-05	2	136	2	38597448
Pubmed	Methylation status of promoters and expression of MUC2 and MUC5AC mucins in pancreatic cancer cells.	MUC2 MUC5AC	1.52e-05	2	136	2	12527922
Pubmed	High-molecular-weight polymers from dietary fiber drive aggregation of particulates in the murine small intestine.	RAG1 MUC2	1.52e-05	2	136	2	30666958
Pubmed	An intestinal epithelial defect conferring ER stress results in inflammation involving both innate and adaptive immunity.	RAG1 MUC2	1.52e-05	2	136	2	21107311
Pubmed	Dopamine receptor D3 expressed on CD4+ T cells favors neurodegeneration of dopaminergic neurons during Parkinson's disease.	RAG1 DRD3	1.52e-05	2	136	2	23589621
Pubmed	Clinically approved immunomodulators ameliorate behavioral changes in a mouse model of hereditary spastic paraplegia type 11.	RAG1 SPG11	1.52e-05	2	136	2	38435059
Pubmed	Regulatory mechanisms and pathophysiological significance of IP3 receptors and ryanodine receptors in drug dependence.	RYR2 ITPR3	1.52e-05	2	136	2	24285081
Pubmed	In vivo glycosylation of mucin tandem repeats.	MUC2 MUC5AC	1.52e-05	2	136	2	11445551
Pubmed	The Innate Immune Sensor NLRC3 Acts as a Rheostat that Fine-Tunes T Cell Responses in Infection and Autoimmunity.	RAG1 NLRC3	1.52e-05	2	136	2	30566882
Pubmed	Fbxo30 Regulates Mammopoiesis by Targeting the Bipolar Mitotic Kinesin Eg5.	FBXO30 KIF11	1.52e-05	2	136	2	27117404
Pubmed	CaMKIIδ mediates β-adrenergic effects on RyR2 phosphorylation and SR Ca(2+) leak and the pathophysiological response to chronic β-adrenergic stimulation.	CAMK2D RYR2	1.52e-05	2	136	2	26080362
Pubmed	The deltaC isoform of CaMKII is activated in cardiac hypertrophy and induces dilated cardiomyopathy and heart failure.	CAMK2D RYR2	1.52e-05	2	136	2	12676814
Pubmed	Temporal analysis of goblet cells and mucin gene expression in murine models of allergic asthma.	MUC2 MUC5AC	1.52e-05	2	136	2	14594655
Pubmed	Abnormal subcellular distribution of mature MUC2 and de novo MUC5AC mucins in adenomas of the rectum: immunohistochemical detection using non-VNTR antibodies to MUC2 and MUC5AC peptide.	MUC2 MUC5AC	1.52e-05	2	136	2	12820724
Pubmed	CaM Kinase II mediates maladaptive post-infarct remodeling and pro-inflammatory chemoattractant signaling but not acute myocardial ischemia/reperfusion injury.	CAMK2D CAMK2G	1.52e-05	2	136	2	25193973
Pubmed	Frequency and phenotype of SPG11 and SPG15 in complicated hereditary spastic paraplegia.	SPG11 ZFYVE26	1.52e-05	2	136	2	19917823
Pubmed	hnRNP U protein is required for normal pre-mRNA splicing and postnatal heart development and function.	CAMK2D CAMK2G RYR2	1.63e-05	13	136	3	26039991
Pubmed	Transgenic mouse proteomics identifies new 14-3-3-associated proteins involved in cytoskeletal rearrangements and cell signaling.	WDR7 CAMK2D CAMK2G NF1 HOMER1 DYNC1H1	2.57e-05	147	136	6	16959763
Pubmed	The variant Polycomb Repressor Complex 1 component PCGF1 interacts with a pluripotency sub-network that includes DPPA4, a regulator of embryogenesis.	ATR CENPF FBXO11 ITPR3 NOP58 P3H1 FECH TOP1 KIF11	2.76e-05	396	136	9	26687479
Pubmed	Mouse models for hereditary spastic paraplegia uncover a role of PI4K2A in autophagic lysosome reformation.	SPG11 ZFYVE26	4.54e-05	3	136	2	33618608
Pubmed	Topoisomerase 1 inhibitor topotecan delays the disease progression in a mouse model of Huntington's disease.	TOP1 HTT	4.54e-05	3	136	2	28007908
Pubmed	Interaction of calcium/calmodulin-dependent protein kinase IIdeltaC with sorcin indirectly modulates ryanodine receptor function in cardiac myocytes.	CAMK2D RYR2	4.54e-05	3	136	2	17707398
Pubmed	The oxidation-resistant CaMKII-MM281/282VV mutation does not prevent arrhythmias in CPVT1.	CAMK2D RYR2	4.54e-05	3	136	2	34558218
Pubmed	Crucial role for Ca2(+)/calmodulin-dependent protein kinase-II in regulating diastolic stress of normal and failing hearts via titin phosphorylation.	CAMK2D CAMK2G	4.54e-05	3	136	2	23283722
Pubmed	CMYA5 establishes cardiac dyad architecture and positioning.	CMYA5 RYR2	4.54e-05	3	136	2	35449169
Pubmed	Differences in the expression of mucins in various forms of cystitis glandularis.	MUC2 MUC5AC	4.54e-05	3	136	2	17659847
Pubmed	Variable SATB1 Levels Regulate Hematopoietic Stem Cell Heterogeneity with Distinct Lineage Fate.	RAG1 STAB1	4.54e-05	3	136	2	29898394
Pubmed	Cadherin-catenin adhesion system and mucin expression: a comparison between young and older patients with gastric carcinoma.	MUC2 MUC5AC	4.54e-05	3	136	2	18825309
Pubmed	Essentiality of Regulator of G Protein Signaling 6 and Oxidized Ca2+/Calmodulin-Dependent Protein Kinase II in Notch Signaling and Cardiovascular Development.	CAMK2D CAMK2G	4.54e-05	3	136	2	29079565
Pubmed	Adenomatous and foveolar gastric dysplasia: distinct patterns of mucin expression and background intestinal metaplasia.	MUC2 MUC5AC	4.54e-05	3	136	2	18300795
Pubmed	Fibulin-2 binds to the short arms of laminin-5 and laminin-1 via conserved amino acid sequences.	LAMA5 FBLN2	4.54e-05	3	136	2	9006922
Pubmed	Neurofibromin and amyloid precursor protein expression in dopamine D3 receptor knock-out mice brains.	DRD3 NF1	4.54e-05	3	136	2	21170735
Pubmed	Expression of aberrant mucins in lobular carcinoma with histiocytoid feature of the breast.	MUC2 MUC5AC	4.54e-05	3	136	2	17333267
Pubmed	Prevalence of arrhythmia-associated gene mutations and risk of sudden cardiac death in the Finnish population.	RYR2 KCNH2	4.54e-05	3	136	2	23651034
Pubmed	Mucin gene polymorphisms in otitis media patients.	MUC2 MUC5AC	4.54e-05	3	136	2	19718741
Pubmed	A conserved ATG2-GABARAP family interaction is critical for phagophore formation.	ATG2B ATG2A	4.54e-05	3	136	2	32009292
Pubmed	Identification of novel human tumor cell-specific CaMK-II variants.	CAMK2D CAMK2G	4.54e-05	3	136	2	9060999
Pubmed	Cloning and quantitative determination of the human Ca2+/calmodulin-dependent protein kinase II (CaMK II) isoforms in human beta cells.	CAMK2D CAMK2G	4.54e-05	3	136	2	10819240
Pubmed	Molecular cloning of testis-abundant finger Protein/Ring finger protein 23 (RNF23), a novel RING-B box-coiled coil-B30.2 protein on the class I region of the human MHC.	TRIM39 TRIM10	4.54e-05	3	136	2	11006080
Pubmed	Cellular distribution and subcellular localization of spatacsin and spastizin, two proteins involved in hereditary spastic paraplegia.	SPG11 ZFYVE26	4.54e-05	3	136	2	21545838
Pubmed	Interaction between AP-5 and the hereditary spastic paraplegia proteins SPG11 and SPG15.	SPG11 ZFYVE26	4.54e-05	3	136	2	23825025
Pubmed	Spastic paraplegia proteins spastizin and spatacsin mediate autophagic lysosome reformation.	SPG11 ZFYVE26	4.54e-05	3	136	2	25365221
Pubmed	Drd3 Signaling in the Lateral Septum Mediates Early Life Stress-Induced Social Dysfunction.	DRD3 ITPR3	4.54e-05	3	136	2	29276054
Pubmed	Calcium/calmodulin kinase II-dependent acetylcholine receptor cycling at the mammalian neuromuscular junction in vivo.	CAMK2D CAMK2G	4.54e-05	3	136	2	20844140
Pubmed	Mice with GFAP-targeted loss of neurofibromin demonstrate increased axonal MET expression with aging.	MET NF1	4.54e-05	3	136	2	17348023
Pubmed	Effects of CaMKII-mediated phosphorylation of ryanodine receptor type 2 on islet calcium handling, insulin secretion, and glucose tolerance.	CAMK2G RYR2	4.54e-05	3	136	2	23516528
Pubmed	Calcium-mediated histone modifications regulate alternative splicing in cardiomyocytes.	CAMK2D NF1	4.54e-05	3	136	2	25368158
Pubmed	A Shld1-controlled POT1a provides support for repression of ATR signaling at telomeres through RPA exclusion.	ATR RPA1	4.54e-05	3	136	2	21070964
Pubmed	Calcium/calmodulin-dependent protein kinase II couples Wnt signaling with histone deacetylase 4 and mediates dishevelled-induced cardiomyopathy.	CAMK2D CAMK2G	4.54e-05	3	136	2	25489064
Pubmed	Gene expression profiling of colorectal mucinous adenocarcinomas.	MUC2 MUC5AC	4.54e-05	3	136	2	20485009
Pubmed	RPA and ATR link transcriptional stress to p53.	ATR RPA1	4.54e-05	3	136	2	17616578
Pubmed	Neurofibromin as a regulator of melanocyte development and differentiation.	NF1 MITF	4.54e-05	3	136	2	18089649
Pubmed	CaMKII Serine 280 O-GlcNAcylation Links Diabetic Hyperglycemia to Proarrhythmia.	CAMK2D CAMK2G	4.54e-05	3	136	2	33926209
Pubmed	NBS1 mediates ATR-dependent RPA hyperphosphorylation following replication-fork stall and collapse.	ATR RPA1	4.54e-05	3	136	2	18003706
Pubmed	Clinicopathological and prognostic significance of MUC-2, MUC-4 and MUC-5AC expression in japanese gastric carcinomas.	MUC2 MUC5AC	4.54e-05	3	136	2	23464473
Pubmed	Phosphorylation of Serine 235 of the Hepatitis C Virus Non-Structural Protein NS5A by Multiple Kinases.	CAMK2D CAMK2G	4.54e-05	3	136	2	27875595
Pubmed	Calmodulin kinase II-mediated sarcoplasmic reticulum Ca2+ leak promotes atrial fibrillation in mice.	CAMK2G RYR2	4.54e-05	3	136	2	19603549
Pubmed	Meconium ileus in cystic fibrosis is not linked to central repetitive region length variation in MUC1, MUC2, and MUC5AC.	MUC2 MUC5AC	4.54e-05	3	136	2	24920497
Pubmed	H4K20me0 recognition by BRCA1-BARD1 directs homologous recombination to sister chromatids.	KIF23 SUPT20H ATR CENPF FBXO11 ITPR3 NOP58 KANSL2 ZBTB39 ZBED4 EHMT2 TRIM28 MITF RPA1 ANAPC5 TOP1	4.86e-05	1294	136	16	30804502
Pubmed	The RNA binding protein MEX3A promotes tumor progression of breast cancer by post-transcriptional regulation of IGFBP4.	IRF2BP2 CENPF ZBED4 TRIM28 DSTYK HELZ2 IRF2BPL DYNC1H1	5.17e-05	332	136	8	37433992
Pubmed	Large-scale characterization of HeLa cell nuclear phosphoproteins.	IRF2BP2 KIF23 ATR MICALL1 TRIM16 KANSL2 NF1 TRIM28 HELZ2 IRF2BPL ANAPC5 MN1	5.56e-05	774	136	12	15302935
Pubmed	Systematic mapping of genetic interactions for de novo fatty acid synthesis identifies C12orf49 as a regulator of lipid metabolism.	KIF23 SUPT20H SZT2 CAMK2G FBXO11 SPG11 ZDBF2 TRIM16 NOP58 NF1 ZBED4 EHMT2 TRIM28 FECH SCAPER HTT	6.53e-05	1327	136	16	32694731
Pubmed	Proteins recruited by SH3 domains of Ruk/CIN85 adaptor identified by LC-MS/MS.	IRF2BP2 KIF23 MICALL1 RPA1 ANAPC5	6.85e-05	108	136	5	19531213
Pubmed	NuMorph: Tools for cortical cellular phenotyping in tissue-cleared whole-brain images.	NF1 TOP1	9.06e-05	4	136	2	34644582
Pubmed	Activation of the ATR kinase by the RPA-binding protein ETAA1.	ATR RPA1	9.06e-05	4	136	2	27723717
Pubmed	Huntingtin facilitates dynein/dynactin-mediated vesicle transport.	DYNC1H1 HTT	9.06e-05	4	136	2	17548833
Interaction	BCAN interactions	LAMA5 FBXO11 ZDBF2 FBLN2 HTT	3.58e-06	36	132	5	int:BCAN
Interaction	GALNT14 interactions	LYZL1 GPIHBP1 MUC2 MUC5AC	1.17e-05	22	132	4	int:GALNT14
GeneFamily	Ring finger proteins\|Tripartite motif containing\|ARF GTPase family	TRIM39 CMYA5 TRIM23 TRIM10 TRIM16 TRIM28	7.83e-06	95	90	6	59
GeneFamily	Kinesins\|Pleckstrin homology domain containing	KIF23 KIF21A STARD9 KIF11	7.98e-05	46	90	4	622
GeneFamily	Zinc fingers FYVE-type\|Pleckstrin homology domain containing\|Rho guanine nucleotide exchange factors	MTMR4 ZFYVE26 WDFY3	4.85e-04	31	90	3	81
GeneFamily	Lysozymes, c-type	LYZL1 LYZL2	8.62e-04	9	90	2	1174
GeneFamily	UPF1 like RNA helicases	ZNFX1 HELZ2	1.31e-03	11	90	2	1169
GeneFamily	Laminin subunits	LAMA5 LAMB3	1.57e-03	12	90	2	626
GeneFamily	Zinc fingers C2H2-type\|ZF class homeoboxes and pseudogenes	ZNF484 ZNF559 ZNF652 ZFY ZBTB39 KLF10 ZNF667 SCAPER ZNF432 ZNF615	2.99e-03	718	90	10	28
GeneFamily	CD molecules\|Mucins	MUC2 MUC5AC	4.84e-03	21	90	2	648
Coexpression	GSE32986_UNSTIM_VS_CURDLAN_HIGHDOSE_STIM_DC_DN	YPEL3 ICAM2 ATG2B TTYH2 ARMC2 UBA7 PLA2G6 TBCEL	9.16e-06	200	134	8	M8618
Coexpression	GSE2405_S_AUREUS_VS_A_PHAGOCYTOPHILUM_NEUTROPHIL_DN	SZT2 ATG2B TRIM39 FBXO30 UBA7 KCNH2 HELZ2 ZFYVE26	9.16e-06	200	134	8	M6208
ToppCell	E16.5-samps-Endothelial-Immature_fetal_endothelial-Intermediate_Endothelial\|E16.5-samps / Age Group, Lineage, Cell class and subclass	CTTNBP2 ICAM2 ACVRL1 RYR2 TRIM16 GPIHBP1 ACKR3 HELZ2	8.29e-08	182	134	8	fec1caf867b1dc87b24504d895ee1a27df78062e
ToppCell	356C-Myeloid-Macrophage-FABP4+_Macrophage\|356C / Donor, Lineage, Cell class and subclass (all cells)	LAMA5 ITGB8 HARBI1 STAB1 MET EML5 ZNF615	5.43e-07	159	134	7	24f87c666eff10c1844c900ffd7ad49fa9f80481
ToppCell	PND07-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-VEC-VEC_G2M\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	KIF23 CTTNBP2 CENPF FBLN2 ZBED4 ACKR3 KIF11	9.96e-07	174	134	7	6c36d607c48267a75ab4da6fb2fe3f931d1b3b52
ToppCell	5'-Adult-LymphNode-Hematopoietic-Myeloid-Mast_cell\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CTTNBP2 ZDHHC1 PHKA1 KCNH2 FECH ZNF667 MITF	1.07e-06	176	134	7	0d203682c372411ba64e97a8eae6c4788e8b6ecf
ToppCell	severe_influenza-RBC\|severe_influenza / disease group, cell group and cell class (v2)	ATG2B FBXO30 TRIM10 KCNH2 FECH TOP1 TBCEL	1.99e-06	193	134	7	ffb0b3c2cce13b6891157f0fede2600f3938670e
ToppCell	Sigmoid-T_cell-cycling_gd_T\|T_cell / Region, Cell class and subclass	KIF23 CENPF TRIM16 ZFYVE26 CCDC136 TBCEL KIF11	2.52e-06	200	134	7	4e489ecf472857357d45e9f6c7a812aa48b72ebf
ToppCell	LPS_only-Hematopoietic_Erythro-Megakary\|LPS_only / Treatment groups by lineage, cell group, cell type	KIF23 CENPF FBXO30 TRIM10 FECH TOP1 KIF11	2.52e-06	200	134	7	ce8281c9556a1f64f8ca8a029110077d4ef5b35e
ToppCell	LPS_only-Hematopoietic_Erythro-Megakary-Erythro-Mega-Erythroid\|LPS_only / Treatment groups by lineage, cell group, cell type	KIF23 CENPF FBXO30 TRIM10 FECH TOP1 KIF11	2.52e-06	200	134	7	83c4181c083b364f0d3a89ae7a0504781fa9fa9f
ToppCell	LPS_only-Hematopoietic_Erythro-Megakary-Erythro-Mega\|LPS_only / Treatment groups by lineage, cell group, cell type	KIF23 CENPF FBXO30 TRIM10 FECH TOP1 KIF11	2.52e-06	200	134	7	f15baf287ec467664c23faa53fdea45257f7b9d0
ToppCell	LPS-IL1RA-Myeloid-Monocytes,_Macrophages-Erythroid\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	CENPF FBXO30 TRIM10 FECH MN1 KIF11	4.96e-06	144	134	6	7c471e332f87d60f4dbed01f3e66bf39995218d0
ToppCell	E16.5-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-VEC-VEC_prolif\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ICAM2 MET UBA7 FBLN2 KLF10 ACKR3	1.37e-05	172	134	6	8a6a2b4c6654bc976e60a02d0e7303a9071ed55f
ToppCell	3'-GW_trimst-1.5-SmallIntestine-Neuronal-Glial_immature-ENCC/glia_Progenitor\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	YPEL3 KIF21A KYAT1 PHKA1 KHDC1L EHMT2	1.42e-05	173	134	6	23e50492bc673aff9df95d97f0b9be4ce57cbf01
ToppCell	PND07-28-samps-Endothelial-Postnatal_endothelial-endothelial_cells_C\|PND07-28-samps / Age Group, Lineage, Cell class and subclass	CTTNBP2 ICAM2 ACVRL1 TRIM23 GPIHBP1 ACKR3	1.61e-05	177	134	6	6da88c358b3a2e47fa3472217a38b6b00ad7b280
ToppCell	droplet-Lung-LUNG-30m-Endothelial-Artery_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LAMA5 ZDHHC1 STAB1 FBLN2 MANSC4 DLEC1	1.72e-05	179	134	6	a09647750eba9d93c5efc1db3b555fefb5eec7b5
ToppCell	wk_15-18-Hematologic-Meg-ery-Definitive_erythroblast\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	ATG2B FBXO30 TRIM10 FECH TOP1 TBCEL	1.89e-05	182	134	6	93841f730ca1a735eaaf5f2ccbe5c45ab0e029d1
ToppCell	droplet-Lung-30m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell-pulmonary_artery_endothelial_cell_l25\|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	LAMA5 ZDHHC1 STAB1 FBLN2 MANSC4 HYDIN	1.95e-05	183	134	6	6f8f997ffc9eaebca2683de125b6069d07c07d26
ToppCell	3'_v3-lymph-node_spleen-Hematopoietic_progenitors-Cycling_pre-Myeloid-2\|lymph-node_spleen / Manually curated celltypes from each tissue	KIF23 CENPF ALPK1 P3H1 ZFYVE26 KIF11	2.20e-05	187	134	6	3c10b8501226c69d71bcd99dc1c064a3c2154f87
ToppCell	Megakaryocytic-erythropoietic-Erythro-cells\|World / Lineage, cell class and subclass	CENPF TRIM10 KCNH2 FECH TOP1 TBCEL	2.40e-05	190	134	6	6c7e016a9b425ee9418acd4fe96b9779fe7bd39a
ToppCell	droplet-Marrow-BM_(NON-STC)-30m-Myeloid-granulocytopoietic_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KIF23 CENPF TRIM10 FECH TOP1 KIF11	2.40e-05	190	134	6	4288189e3a499c395896c950598810b02f401685
ToppCell	E17.5-Endothelial-proliferative_endothelial_cell-proliferative_endothelial_cell\|E17.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	KIF23 CENPF ICAM2 ACVRL1 GPIHBP1 KIF11	2.47e-05	191	134	6	efe0cb0b6602621f5eda72a723b83b38bf15607f
ToppCell	LA-03._Atrial_Cardiomyocyte\|LA / Chamber and Cluster_Paper	CAMK2D KIF21A CMYA5 RYR2 MITF HOMER1	2.47e-05	191	134	6	5d1b674eb7703830b7ce8bbeac3363cabd0e6ae9
ToppCell	E17.5-Endothelial-proliferative_endothelial_cell\|E17.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	KIF23 CENPF ICAM2 ACVRL1 GPIHBP1 KIF11	2.47e-05	191	134	6	00676c598f6dae0ff9158d064248f1265432f3e1
ToppCell	droplet-Heart-nan-24m-Mesenchymal-cardiomyocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LAMB3 POPDC2 CMYA5 RYR2 KCNH2 HOMER1	2.55e-05	192	134	6	f6a4e348406a852ace9fb21db8fbdff539217645
ToppCell	droplet-Heart-nan-24m-Mesenchymal-atrial_cardiomyocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LAMB3 POPDC2 CMYA5 RYR2 KCNH2 HOMER1	2.55e-05	192	134	6	1a0c25106ae08eac912a4edd5fc1a3ee776f69c2
ToppCell	Influenza_Severe-RBC\|Influenza_Severe / Disease group and Cell class	ATG2B FBXO30 TRIM10 FECH TOP1 TBCEL	2.55e-05	192	134	6	f19b6da3fd98da1a76d2570137a8f73a3850ebcb
ToppCell	Fibroblasts-CD55+_Fibroblasts\|World / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues	CTTNBP2 CFI ITGB8 MET ACKR3 MN1	2.62e-05	193	134	6	8f4bf9a2fbedae35432dad96730b00c70185874c
ToppCell	Megakaryocytic-erythropoietic-Erythro-cells-Polychromatic_Erythroblast\|World / Lineage, cell class and subclass	KIF23 CENPF TRIM10 KCNH2 FECH KIF11	2.70e-05	194	134	6	008bb0072f414a48d052429101bdc990ee4f80c2
ToppCell	RA-03._Atrial_Cardiomyocyte\|World / Chamber and Cluster_Paper	CAMK2D KIF21A CMYA5 RYR2 MITF HOMER1	2.70e-05	194	134	6	89812fb164065041357bb37a3c2d87028ec3de4e
ToppCell	RA-03._Atrial_Cardiomyocyte\|RA / Chamber and Cluster_Paper	CAMK2D KIF21A CMYA5 RYR2 MITF HOMER1	2.70e-05	194	134	6	c3535f7cc0076653c72db582047cff053c322397
ToppCell	COVID-19-Heart-CM_1\|Heart / Disease (COVID-19 only), tissue and cell type	KIF21A POPDC2 CMYA5 RYR2 MITF HOMER1	2.78e-05	195	134	6	f1ef50331eda8f1239dba6ea970df4eaccf032f1
ToppCell	E18.5-Endothelial-Endothelial_blood-vessel-Microvascular_EC-EPC-EPC_G2M\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	KIF23 CENPF ICAM2 ACVRL1 GPIHBP1 KIF11	2.78e-05	195	134	6	a838bddeed487154791b69d27a68673783ff63c0
ToppCell	LPS_IL1RA_TNF-Hematopoietic_Erythro-Megakary\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	NLRP7 CENPF FBXO30 TRIM10 FECH KIF11	3.11e-05	199	134	6	f894c88ecc7fd0edca28587801fa59352d10f750
ToppCell	Influenza-Influenza_Severe-Others-RBC\|Influenza_Severe / Disease, condition lineage and cell class	ATG2B FBXO30 KCNH2 FECH TOP1 TBCEL	3.11e-05	199	134	6	da0fec0a492bc3827d9066d2590bcd466cd45564
ToppCell	LPS_IL1RA_TNF-Hematopoietic_Erythro-Megakary-Erythro-Mega\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	NLRP7 CENPF FBXO30 TRIM10 FECH KIF11	3.11e-05	199	134	6	2b754670fe77c2301afcdcfc73a1e52cc0cd1de3
ToppCell	LPS_IL1RA_TNF-Hematopoietic_Erythro-Megakary-Erythro-Mega-Erythroid\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	NLRP7 CENPF FBXO30 TRIM10 FECH KIF11	3.20e-05	200	134	6	f100edfd2b3b742458cbbf34de9c403c4d272d3c
ToppCell	LPS_IL1RA-Hematopoietic_Erythro-Megakary-Erythro-Mega-Erythroid\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	CENPF FBXO30 TRIM10 FECH TOP1 KIF11	3.20e-05	200	134	6	fa1eaf008b54bdf7bbcdec8134460c5f64490de9
ToppCell	Sigmoid-(1)_T_cell-(18)_cycling_gd_T\|Sigmoid / shred on region, Cell_type, and subtype	KIF23 CENPF TRIM16 ZFYVE26 CCDC136 KIF11	3.20e-05	200	134	6	6e367abd1a4b87e20eb9095b8337723163e8bbae
ToppCell	Calu_3\|World / Cell line, Condition and Strain	LAMA5 LAMB3 ITGB8 ITPR3 HELZ2 MUC5AC	3.20e-05	200	134	6	a549aa08aeefe905653266dae3936094ff55f8e4
ToppCell	Sigmoid-T_cell-cycling_gd_T\|Sigmoid / Region, Cell class and subclass	KIF23 CENPF TRIM16 ZFYVE26 CCDC136 KIF11	3.20e-05	200	134	6	9769185abae084ffac36420c749625e679b70ca8
ToppCell	Hippocampus-Endothelial-ENDOTHELIAL_STALK\|Hippocampus / BrainAtlas - Mouse McCarroll V32	ICAM2 CFI TRIM16 GPIHBP1 HELZ2	6.35e-05	139	134	5	34398a6f21a1e670497655a7bb7f3cde9e117560
ToppCell	Hippocampus-Endothelial-ENDOTHELIAL_STALK-Flt1_2\|Hippocampus / BrainAtlas - Mouse McCarroll V32	ICAM2 CFI TRIM16 GPIHBP1 HELZ2	6.35e-05	139	134	5	450c4152c9fe4ec503271bb3cf93739918c59509
ToppCell	Thalamus-Endothelial-ENDOTHELIAL_STALK-Flt1_2-Endothelial_Stalk.Flt1.Pi16_(Pi16)\|Thalamus / BrainAtlas - Mouse McCarroll V32	KIF23 GPR39 ICAM2 ACVRL1 ITPR3	7.03e-05	142	134	5	58bfff3284ae21150e4619511bd58622c16c5dde
ToppCell	Thalamus-Endothelial-ENDOTHELIAL_STALK-Flt1_2-Endothelial_Stalk.Flt1.Pi16_(Pi16)--\|Thalamus / BrainAtlas - Mouse McCarroll V32	KIF23 GPR39 ICAM2 ACVRL1 ITPR3	7.03e-05	142	134	5	5fd737c1fee9d97aee8955f1bf378ead3fce138d
ToppCell	Thalamus-Endothelial-ENDOTHELIAL_STALK-Flt1_2-Endothelial_Stalk.Flt1.Pi16_(Pi16)-\|Thalamus / BrainAtlas - Mouse McCarroll V32	KIF23 GPR39 ICAM2 ACVRL1 ITPR3	7.03e-05	142	134	5	16f9945e835c3506b12d904778560d065a50f059
ToppCell	pdx-Tumor_cells-T9\|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)	FBXO11 ZNFX1 MICALL1 TOP1 DYNC1H1	7.51e-05	144	134	5	0b94d978262a826c9254145aa98c6c30240243f9
ToppCell	primary_visual_cortex-Neuronal-glutamatergic_neuron-NP-L5_NP_VISp_Trhr_Met\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	GPR39 CAMK2D MCC ACVRL1 MET	7.76e-05	145	134	5	8abbc781f5f69f039617c29a5589d7b6950c2c40
ToppCell	LPS_only-Epithelial_alveolar-AT_1-AT2_Progenitor\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	KIF21A LAMB3 EML5 UMOD HOMER1	9.99e-05	153	134	5	e7a074ea8232bacf924be78a244a8507c7e1ebc8
ToppCell	Enthrocyte\|World / shred on cell class and cell subclass (v4)	FBXO30 TRIM10 LRRC31 FECH TBCEL	9.99e-05	153	134	5	654265f3c14344071b2af7ca05cbdbb17ce2c5d3
ToppCell	Enthrocyte\|World / shred on cell class and cell subclass (v4)	FBXO30 TRIM10 LRRC31 FECH TBCEL	9.99e-05	153	134	5	105b91f5277d145f7717307d7eb9b7d8e8e23576
ToppCell	facs-Marrow-Granulocytes-3m-Hematologic\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KIF21A TRIM39 ARMC2 EML5 PLA2G6	1.06e-04	155	134	5	cd2f3ad4f131588325a667b6724e530d821fbe30
ToppCell	facs-Marrow-Granulocytes-3m-Hematologic-MPP_Fraction_B\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KIF21A TRIM39 ARMC2 EML5 PLA2G6	1.06e-04	155	134	5	9b26ade19488511c72b64335011d2dcd81e8f167
ToppCell	facs-Marrow-Granulocytes-3m-Hematologic-hematopoietic_stem_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KIF21A TRIM39 ARMC2 EML5 PLA2G6	1.06e-04	155	134	5	4246709e27703b94529369abbed5763e4002e79d
ToppCell	facs-Liver-Non-hepatocytes-3m-Endothelial-nan\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ANKMY1 STAB1 ZBTB39 GPIHBP1 HYDIN	1.06e-04	155	134	5	8fdda4e3657ac56188ae88ed3caf145f4d9d1567
ToppCell	PND07-Endothelial-Endothelial_blood-vessel-Microvascular_EC-EPC-EPC_mature\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ACVRL1 STAB1 PHKA1 GPIHBP1 EXD2	1.09e-04	156	134	5	1928c86deb3bcd01db4ae76919a351066aadb39a
ToppCell	PND03-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP1-CAP1_prolif\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ICAM2 ACVRL1 ZBTB39 GPIHBP1 MUC5AC	1.13e-04	157	134	5	2c946c6ab284fac3c25db688ed0aabe5a3f9ffa5
ToppCell	Entopeduncular-Endothelial-ENDOTHELIAL_STALK\|Entopeduncular / BrainAtlas - Mouse McCarroll V32	ICAM2 ACVRL1 ITPR3 TRIM16 UBA7	1.23e-04	160	134	5	04714d0b9bad4c11fa193ed168e2d84a4df39e2e
ToppCell	droplet-Heart-HEART_(ALL_MINUS_AORTA)-30m-Hematologic-red_blood_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TRIM10 GPIHBP1 FECH HYDIN	1.32e-04	86	134	4	1f44bb41835445aa60a2e3c31616c5847447a246
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Afferent_/_Efferent_Arteriole_Endothelial_Cell_prolif\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	MATN3 ICAM2 FBLN2 GPIHBP1 MN1	1.34e-04	163	134	5	1feb4ef7b8abcfca9a72c8d13c40548de79e7db2
ToppCell	NS-moderate-d_16-33-Myeloid-Mast_cell\|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	CTTNBP2 TTYH2 ADGRB2 KCNH2 ZNF667	1.38e-04	164	134	5	35c673380f75cb4bfe080089bc723c4373bcc7a5
ToppCell	facs-Marrow-KLS-3m-Hematologic-megakaryocyte-erythroid_progenitor_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ABHD3 FBXO30 TRIM10 FECH TBCEL	1.42e-04	165	134	5	4f95c2fe5ab4416c736fe0d1936695a2b26777eb
ToppCell	facs-Marrow-KLS-3m-Hematologic-megakaryocyte-erythroid_progenitor_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ABHD3 FBXO30 TRIM10 FECH TBCEL	1.42e-04	165	134	5	3e913b49a868fdd5589200ae3e9be77c0938ba14
ToppCell	356C-Myeloid-Macrophage-FABP4+_Macrophage\|Myeloid / Donor, Lineage, Cell class and subclass (all cells)	LAMA5 CFI MET EML5 ZNF615	1.46e-04	166	134	5	89e2b8453180983533faccb4275867861876d7ee
ToppCell	droplet-Marrow-nan-24m-Myeloid-granulocyte\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	YPEL3 FBXO30 TRIM10 FECH TBCEL	1.51e-04	167	134	5	54576e9863403d0d5e3046e61db1ad695d88fee4
ToppCell	droplet-Bladder-BLADDER-1m-Epithelial-basal_bladder_epithelial_cell_(Krt5+Krt14+)\|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IRF2BP2 KIF23 IRF2BPL NLRC3 TBCC	1.55e-04	168	134	5	ca65321259711321c175ede67bd67a47aad81d7a
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Outer_Medullary_Collecting_Duct_Intercalated_Cell_Type_A\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	KIF21A MCC TOP6BL THSD7B ANKRD44	1.59e-04	169	134	5	2a21f2cef959526bfe3c8f081f4f7e9dd4e01a37
ToppCell	normal_Pleural_Fluid-Myeloid_cells-CD163+CD14+_DCs\|Myeloid_cells / Location, Cell class and cell subclass	ZDBF2 TOP6BL KANSL2 EHMT2 ACKR3	1.59e-04	169	134	5	bea8aba1f3cc3d0e8d448c1c45f5354d26ebf850
ToppCell	E16.5-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-VEC\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ICAM2 ACVRL1 FBLN2 ACKR3 MUC2	1.64e-04	170	134	5	af8b56555cbd5a1016ab9ec2ce88225c58c89648
ToppCell	facs-Heart-Unknown-3m-Mesenchymal-atrial_myocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LAMB3 POPDC2 CMYA5 RYR2 KCNH2	1.73e-04	172	134	5	ee8ce9e8c9a6d3ee2be113f77743958005f4b3f0
ToppCell	AT1-AT2_cells-Cryobiopsy_01\|World / lung cells shred on cell class, cell subclass, sample id	HCAR1 LAMA5 LAMB3 CFI MUC5AC	1.73e-04	172	134	5	0be41df5d35d818deb7316ac21c9366eb4b7bfd1
ToppCell	facs-Heart-Unknown-3m-Mesenchymal-atrial_cardiomyocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LAMB3 POPDC2 CMYA5 RYR2 KCNH2	1.73e-04	172	134	5	bd468a7ea6ec832dcf6a816a1e0c03fa0f176dad
ToppCell	E16.5-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-VEC-VEC_mature\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ICAM2 ACVRL1 FBLN2 ACKR3 MUC2	1.73e-04	172	134	5	9a1743abcd5fbd38253ea84d88ad716cfb71de36
ToppCell	tumor_Lymph_Node_/_Brain-Myeloid_cells-Pleural_Mac\|tumor_Lymph_Node_/_Brain / Location, Cell class and cell subclass	TTYH2 STAB1 SCPEP1 ZFYVE26 PRR14L	1.77e-04	173	134	5	8384d533a1071fc65a06e6d9f5f17d8ab00c3966
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	KIF21A MCC TOP6BL THSD7B ANKRD44	1.77e-04	173	134	5	0bc2aacae60c6d3276b0949eb0748b4ac1f56e54
ToppCell	10x5'-lymph-node_spleen-Hematopoietic_progenitors-Cycling_pre-Myeloid-2\|lymph-node_spleen / Manually curated celltypes from each tissue	KIF23 CENPF STAB1 WDFY3 KIF11	1.77e-04	173	134	5	783b8fa08b9d8f597f251793eae164151662f1f9
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW19-Neuronal-Neuron\|GW19 / Sample Type, Dataset, Time_group, and Cell type.	TTYH2 ATG2A STARD9 IRF2BPL RPA1	1.87e-04	175	134	5	2812ac2ef41d245db544697fb6da1883361c96e8
ToppCell	PND03-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-VEC-VEC_G2M\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	KIF23 CENPF FBLN2 ACKR3 KIF11	1.87e-04	175	134	5	d43ae33a6256606ce848247cad32d74f21b38988
ToppCell	facs-Aorta\|facs / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ICAM2 HCAR1 GPIHBP1 HYDIN OTOG	1.92e-04	176	134	5	0b3491451be02c18a16cdb875645be47eb867a7f
ToppCell	droplet-Pancreas-Exocrine-18m-Endothelial-endothelial_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ICAM2 ACVRL1 FBLN2 GPIHBP1 ACKR3	1.92e-04	176	134	5	eb63eb2c301e785196ccadac74a2940b2c524c62
ToppCell	droplet-Marrow-BM-1m-Lymphocytic-late_pro-B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TRIM23 ITPR3 MTMR4 ZNF667 SCPEP1	1.92e-04	176	134	5	2e9073166da4d9fae70ba4f3fdcad35523caf7cd
ToppCell	PND10-Immune-Immune_Myeloid-Monocytic-Macrophage-iMON-iMON_G2M\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CENPF HLCS HARBI1 ZBED4 ZFYVE26	1.92e-04	176	134	5	90f8bb11f339f67f08692a0c33dd420f5cda2861
ToppCell	droplet-Kidney-KIDNEY-30m-Endothelial-Pecam____kidney_capillary_endothelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ICAM2 CMYA5 STAB1 GPIHBP1 MN1	1.92e-04	176	134	5	c4d9166e5bbb7ca544107db14e4374289f5de6bd
ToppCell	PND01-Endothelial-Endothelial_blood-vessel-Microvascular_EC-EPC-EPC_G2M\|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	KIF23 CENPF GPIHBP1 NLRC3 KIF11	1.92e-04	176	134	5	8385435074cc5235b7af7424974f609388fc2cff
ToppCell	droplet-Kidney-KIDNEY-30m-Endothelial-kidney_capillary_endothelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ICAM2 CMYA5 STAB1 GPIHBP1 MN1	1.92e-04	176	134	5	d58ef51002ea50b3037636038214bbb7454cb503
ToppCell	Healthy-RBC\|World / disease group, cell group and cell class	KIF23 HCAR1 TRIM10 FECH TBCEL	1.97e-04	177	134	5	2ce41e37fa7139c7bd2b464bd86c5601dc501515
ToppCell	kidney_cells-Adult_normal_reference-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_cortex\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ZNF484 STAB1 FBLN2 ACKR3 KIF11	1.97e-04	177	134	5	227d4f423b00be2e0c5797e2c5275d342e69a0f4
ToppCell	kidney_cells-Adult_normal_reference-Endothelial-lymphatic_endothelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ZNF484 STAB1 FBLN2 ACKR3 KIF11	1.97e-04	177	134	5	66ffa279147961080c104242a08b176e301d80e3
ToppCell	Healthy-RBC\|Healthy / disease group, cell group and cell class	KIF23 HCAR1 TRIM10 FECH TBCEL	1.97e-04	177	134	5	945d72ab52efa9a9468daace9f9ec676a891d963
ToppCell	kidney_cells-Adult_normal_reference-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_cortex-lymphatic_endothelial_cell_of_renal_cortex\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ZNF484 STAB1 FBLN2 ACKR3 KIF11	1.97e-04	177	134	5	0cbf54608d2ba0a0500af142f2029fe5e118c3c2
ToppCell	Children_(3_yrs)-Epithelial-basal_cell\|Children_(3_yrs) / Lineage, Cell type, age group and donor	GPR39 MCC LAMA5 LAMB3 MET	2.03e-04	178	134	5	fba2e38c05cbf031e0c6d47b1602575fea734a57
ToppCell	LPS-IL1RA+antiTNF-Hematopoietic_Meg-Ery\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	YPEL3 FBXO30 TRIM10 FECH TBCEL	2.08e-04	179	134	5	7329b45376a9e9a4fe34d4aa0b33af6dda0a8e3b
ToppCell	LPS-IL1RA+antiTNF-Hematopoietic_Meg-Ery-Erythroid\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	YPEL3 FBXO30 TRIM10 FECH TBCEL	2.08e-04	179	134	5	6e4740f99f66d3e9348fa5057cf1030454819aa8
ToppCell	E16.5-samps-Endothelial-Immature_fetal_endothelial-Proliferative_Endothelial\|E16.5-samps / Age Group, Lineage, Cell class and subclass	ICAM2 ACVRL1 TRIM16 GPIHBP1 ACKR3	2.08e-04	179	134	5	d24513a404c9b1d37dd47aa1cdb5713b64b88f89
ToppCell	Epithelial-basal_cell\|World / Lineage, Cell type, age group and donor	MCC LAMA5 LAMB3 TOP6BL MET	2.08e-04	179	134	5	d9be6647ec7b22747dc00dce4ea307b6af412dfa
ToppCell	LPS-IL1RA+antiTNF-Hematopoietic_Meg-Ery-Erythroid-Erythroid\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	YPEL3 FBXO30 TRIM10 FECH TBCEL	2.08e-04	179	134	5	ee60ac43fb62c09967a26bbcf9306ac5ea2bdc1e
ToppCell	10x5'-lymph-node_spleen-Myeloid_Mac-Cycling_Myeloid-Mac\|lymph-node_spleen / Manually curated celltypes from each tissue	KIF23 CENPF STAB1 WDFY3 KIF11	2.13e-04	180	134	5	4eea8366cdb82c356325ce88f09ad8b302c17a07
ToppCell	MS-Treg-naive_CD4\|MS / Condition, Cell_class and T cell subcluster	CENPF TOP6BL TRIM16 P3H1 PRR14L	2.13e-04	180	134	5	7ca083616926d98420fa11a6e5ebc981623f79ac
ToppCell	356C-Lymphocytic-CD4_T-cell-Proliferating_T_cell\|356C / Donor, Lineage, Cell class and subclass (all cells)	KIF23 CENPF ZNF385D KCNH2 KIF11	2.19e-04	181	134	5	be4f35c9eb5b3083acb2264128f095fac1f3da45
ToppCell	5'-GW_trimst-2-SmallIntestine-Endothelial-blood_vessel_EC-Mature_arterial_EC\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ICAM2 ACVRL1 PHKA1 MET FBLN2	2.19e-04	181	134	5	0ba91575fe8851788cebc4cf5a6d76680bf586c5
ToppCell	wk_20-22-Hematologic-Meg-ery-Definitive_erythroblast\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	ATG2B ATG2A FBXO30 FECH TBCEL	2.25e-04	182	134	5	0c77ef4556c1d1512ebe9077df858b28f9e38dd5
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	CTTNBP2 ITGB8 MET WDFY3 HYDIN	2.30e-04	183	134	5	738e94b50c4c08c727d4eed0708dda08aa6891b4
Drug	Meprylcaine hydrochloride [956-03-6]; Down 200; 14.8uM; PC3; HT_HG-U133A	HLCS FBXO11 ANKMY1 ALPK1 NF1 P3H1 PRR14L WDFY3 ZMYM5	2.34e-06	196	133	9	5723_DN
Drug	Harpagoside [19210-12-9]; Down 200; 8uM; MCF7; HT_HG-U133A	CAMK2G ZNF652 HLCS ALPK1 MICALL1 MET NF1 DSTYK	1.70e-05	191	133	8	4981_DN
Drug	Demeclocycline hydrochloride [64-73-3]; Down 200; 8uM; MCF7; HT_HG-U133A	CAMK2G HLCS TOP6BL MICALL1 MET NF1 WDFY3 TBCEL	1.90e-05	194	133	8	3604_DN
Drug	Practolol [6673-35-4]; Down 200; 15uM; MCF7; HT_HG-U133A	CAMK2G HLCS TRIM23 RYR2 MET NF1 SCAPER ANAPC5	2.04e-05	196	133	8	3204_DN
Drug	Colistin sulfate [1264-72-8]; Up 200; 3uM; MCF7; HT_HG-U133A	ZNF652 APAF1 MCC ALPK1 KYAT1 NF1 KCNH2 MITF	2.04e-05	196	133	8	2851_UP
Drug	(-)-MK 801 hydrogen maleate [77086-19-2]; Down 200; 11.8uM; PC3; HT_HG-U133A	SUPT20H HLCS ALPK1 ITGB8 NF1 ZNF667 PLA2G6 ANAPC5	2.20e-05	198	133	8	6657_DN
Drug	N6,2-O-dibutyryladenosine 3,5-cyclic monophosphate sodium salt; Up 200; 2uM; MCF7; HT_HG-U133A_EA	SZT2 ADGRB2 HLCS ALPK1 MET NF1 DSTYK WDFY3	2.20e-05	198	133	8	842_UP
Drug	Oleandomycin phosphate [7060-74-4]; Down 200; 5uM; PC3; HT_HG-U133A	ADGRB2 MET ACKR3 DSTYK SCAPER WDFY3 ANAPC5 ZMYM5	2.28e-05	199	133	8	4615_DN
Drug	15(S)-15-methyl Prostaglandin E2; Down 200; 10uM; PC3; HT_HG-U133A	APAF1 ANKMY1 KYAT1 ITPR3 MET ZNF667 PLA2G6 WDFY3	2.28e-05	199	133	8	7494_DN
Drug	Mafenide hydrochloride [138-37-4]; Up 200; 18uM; PC3; HT_HG-U133A	MATN3 APAF1 RYR2 SCAPER PLA2G6 PRR14L MUC5AC TBCEL	2.28e-05	199	133	8	5079_UP
Drug	Paromomycin sulfate [1263-89-4]; Up 200; 5.6uM; PC3; HT_HG-U133A	SZT2 KLK3 RYR2 STAB1 MET UBA7 NF1 PLA2G6	2.28e-05	199	133	8	4595_UP
Drug	Sulfamethazine sodium salt [1981-58-4]; Down 200; 13.4uM; PC3; HT_HG-U133A	SZT2 ADGRB2 ITGB8 TRIM23 MET NF1 ZNF667 WDFY3	2.36e-05	200	133	8	3765_DN
Disease	cystitis (is_marker_for)	MUC2 MUC5AC	1.84e-05	2	127	2	DOID:1679 (is_marker_for)
Disease	sputum mucin-5B amount	MUC2 MUC5AC	5.50e-05	3	127	2	OBA_2050332
Disease	neurodevelopmental disorder with regression, abnormal movements, loss of speech, and seizures (implicated_via_orthology)	IRF2BP2 IRF2BPL	5.50e-05	3	127	2	DOID:0081327 (implicated_via_orthology)
Disease	gestational trophoblastic neoplasm (is_implicated_in)	NLRP7 TOP6BL	1.10e-04	4	127	2	DOID:3590 (is_implicated_in)
Disease	Complete hydatidiform mole	NLRP7 TOP6BL	1.10e-04	4	127	2	C0678213
Disease	Hereditary Paraganglioma-Pheochromocytoma Syndrome	MET NF1 MITF	1.29e-04	23	127	3	C1708353
Disease	mucinous adenocarcinoma (is_marker_for)	MUC2 MUC5AC	1.82e-04	5	127	2	DOID:3030 (is_marker_for)
Disease	selenium measurement	CMYA5 ANKRD44 HOMER1	2.62e-04	29	127	3	EFO_0006331
Disease	heart conduction disease (implicated_via_orthology)	CAMK2D CAMK2G KCNH2	3.53e-04	32	127	3	DOID:10273 (implicated_via_orthology)
Disease	Rectal Neoplasms	MCC MUC2	3.81e-04	7	127	2	C0034885
Disease	Rectal Carcinoma	MCC MUC2	3.81e-04	7	127	2	C0007113
Disease	diffuse plaque measurement	CAMK2D MATN3 MCC FBXO11 ZDBF2 LYZL1 ZNF385D FBLN2 EHMT2 MITF DLEC1	4.48e-04	758	127	11	EFO_0010699
Disease	bringing up phlegm, sputum or mucus on most days, self-reported	MUC2 MUC5AC	6.49e-04	9	127	2	EFO_0009824
Disease	Colorectal Carcinoma	MCC LAMB3 ADAM29 FBXO30 ZNF385D FBLN2 NF1 TRIM28 ACKR3 ZNF432	9.40e-04	702	127	10	C0009402
Disease	Long QT Syndrome	RYR2 KCNH2	9.86e-04	11	127	2	C0023976
Disease	pneumonia	HELZ2 MUC2 MUC5AC	1.10e-03	47	127	3	EFO_0003106
Disease	Malignant mesothelioma	ICAM2 RYR2 MET MTMR4	1.28e-03	109	127	4	C0345967
Disease	disease recurrence, colon carcinoma	THSD7B ARMC2 MITF	1.39e-03	51	127	3	EFO_0004952, EFO_1001950
Disease	T wave morphology measurement	CAMK2D KCNH2	1.62e-03	14	127	2	EFO_0008398
Disease	Dyskinesia, Medication-Induced	DRD3 HOMER1	1.86e-03	15	127	2	C0751088
Disease	Dyskinesia, Drug-Induced	DRD3 HOMER1	1.86e-03	15	127	2	C0013386
Disease	central nervous system disease (implicated_via_orthology)	IRF2BP2 IRF2BPL	2.12e-03	16	127	2	DOID:331 (implicated_via_orthology)
Disease	Acute Myeloid Leukemia, M1	MET NF1 EHMT2 MN1	2.12e-03	125	127	4	C0026998
Disease	Acute Myeloid Leukemia (AML-M2)	MET NF1 EHMT2 MN1	2.12e-03	125	127	4	C1879321
Disease	Malignant Neoplasms	ATR MET KCNH2 TOP1	2.31e-03	128	127	4	C0006826
Disease	Benign neoplasm of stomach	ATR MET	2.40e-03	17	127	2	C0153943
Disease	Neoplasm of uncertain or unknown behavior of stomach	ATR MET	2.40e-03	17	127	2	C0496905
Disease	Carcinoma in situ of stomach	ATR MET	2.40e-03	17	127	2	C0154060
Disease	cholangiocarcinoma (is_marker_for)	MET MUC2 MUC5AC	2.68e-03	64	127	3	DOID:4947 (is_marker_for)
Disease	Chronic myeloproliferative disorder	ATR CENPF	3.00e-03	19	127	2	C1292778
Disease	Profound Mental Retardation	MCC NF1 SCAPER DYNC1H1	3.12e-03	139	127	4	C0020796
Disease	Mental Retardation, Psychosocial	MCC NF1 SCAPER DYNC1H1	3.12e-03	139	127	4	C0025363
Disease	Mental deficiency	MCC NF1 SCAPER DYNC1H1	3.12e-03	139	127	4	C0917816
Disease	Intellectual Disability	MCC NF1 SCAPER MN1 DYNC1H1 HTT ALG13	3.29e-03	447	127	7	C3714756
Disease	respiratory system disease	ZNF652 ITGB8 MUC2 MUC5AC	3.62e-03	145	127	4	EFO_0000684
Disease	Infiltrating duct carcinoma of female breast	ATR RPS6KC1	3.66e-03	21	127	2	C3165106
Disease	Stomach Carcinoma	ATR MET	3.66e-03	21	127	2	C0699791
Disease	emphysema imaging measurement	PYROXD2 MCC KLK3 DLEC1	3.71e-03	146	127	4	EFO_0007626
Disease	Seckel syndrome	ATR CENPF	4.01e-03	22	127	2	C0265202

Protein segments in the cluster

Peptide	Gene	Start	Entry
TFHCEICDVHVNSET	ZNF385D	266	Q9H6B1
TLETQAAHTRCQCQH	ADGRB2	896	O60241
IHRHCVHITILNSNC	ADAM29	611	Q9UKF5
FVCHQGTVLSCDISH	APAF1	1081	O14727
INSTECLHVHCRGLE	CFI	176	P05156
AISEQLFCSQVHHLE	ALG13	246	Q9NP73
IETVCAACTQLHHAL	ARMC2	286	Q8NEN0
CCANTEDLETVIHHV	ABHD3	191	Q8WU67
HCILQHSNRICVITL	ABITRAM	36	Q9NX38
DSHLCNHNVSLVLEA	ACVRL1	91	P37023
RNITHLQHCTCVDDC	EHMT2	966	Q96KQ7
VACHCHSELALDLAN	ATG2A	576	Q2TAZ0
LRCSNNVVHVHSCAD	ATG2A	1211	Q2TAZ0
NVVHVHSCADSCALL	ATG2A	1216	Q2TAZ0
ELHCSSDVVHIRTCS	ATG2B	1336	Q96BY7
QHVECNEICHRLSLT	ALPK1	1221	Q96QP1
HFVKSISCQICEHIL	RAG1	286	P15918
VHVDNCILNAETLVC	P3H1	586	Q32P28
PCHENQTCIVTHESN	ITPR3	1951	Q14573
SHQECHSQCCIQLRE	LRCOL1	126	A6NCL2
AQESNDHVCLQHCLS	ANAPC5	331	Q9UJX4
VSEEDICNILHLCTQ	NOP58	246	Q9Y2X3
VQVLCCRLSLQHANH	GPR39	356	O43194
ALNTHGCEHICVNDR	MATN3	311	O15232
NNHCHVACSALITDD	LYZL1	91	Q6UWQ5
NNHCHVACSALVTDD	LYZL2	91	Q7Z4W2
CARAINVLHCLHELQ	NLRC3	561	Q7RTR2
QNCSHGQTCTTLIAH	GPIHBP1	81	Q8IV16
VLCLRLSTEQCQAHE	RPS6KC1	731	Q96S38
HHISSCDDRSCIEQD	GTSF1	66	Q8WW33
EQELHNLLEVVSQCC	KIF11	841	P52732
SVIHVLADEVQHCQS	PHKA1	226	P46020
ADICLHLNRSLLQHC	KCNH2	726	Q12809
LHLSSCHECLELENS	HLCS	101	P50747
NSHDVLLLCTSCHAI	EXD2	451	Q9NVH0
EKSSHIILACCVLHN	HARBI1	286	Q96MB7
IILACCVLHNISLEH	HARBI1	291	Q96MB7
LGTHNCSEAETCHNI	FBLN2	1031	P98095
TICHERLEDTHFVQC	IRF2BPL	716	Q9H1B7
NTCVSHISCVLVFHI	OR51B4	236	Q9Y5P0
CLHQEVIQLACTDIT	OR51M1	191	Q9H341
TCSHLEVSSLCEEHR	MUC2	311	Q02817
HLQVLDLHQCSLTAD	LRRC31	311	Q6UY01
DNINCLHVHCPTLES	MANSC4	91	A6NHS7
SSTCAACQQHVHLVQ	MICALL1	161	Q8N3F8
SNQEHSRACEDHCVA	MUC5AC	356	P98088
AANCHFHCIETLVTT	ANKRD44	446	Q8N8A2
SIHCEVCDHCVVLLL	LAMA5	2161	O15230
ALNLVHCHCLDIFIN	DSTYK	361	Q6XUX3
ELECVSSQANAVHTH	HOMER1	231	Q86YM7
CLGLTEEDQHTHLCQ	MTMR4	136	Q9NYA4
NETAKIHIHRNCSCQ	ITGB8	456	P26012
VEEEQLSSNCVCQIH	RPA1	66	P27694
VLQLTALCTVHCSHQ	ATR	496	Q13535
HIEQLTTASEHCDLA	MCC	191	P23508
NHCLTICENIVAQSV	HTT	101	P42858
IFEEHQICTSANLHH	HYDIN	3336	Q4G0P3
DHLLLDTQHCQHSSC	LINC01555	21	Q8NAE3
LESHQSECLHCIQVA	CENPF	1991	P49454
CNRTVHDVATDDCKH	CTTNBP2	946	Q8WZ74
HHCLEITVNCSPIID	FBXO11	361	Q86XK2
VVLSCHDEIENHSLS	CMYA5	2726	Q8N3K9
ALHVTQCLSLVHCCV	ACKR3	296	P25106
ATHCHNDIVNLLLDC	ANKMY1	301	Q9P2S6
EAIVNSCVFVHQTLH	DYNC1H1	3141	Q14204
HCLTHICQDTNQVLF	KANSL2	321	Q9H9L4
CIELHSHTLIQLERC	KHDC1L	46	Q5JSQ8
IRHTADAQLCNHQTC	KLF10	156	Q13118
LLENHLCVQETAVSC	HCAR1	151	Q9BXC0
TAVQVHDVCVCQHNT	LAMB3	271	Q13751
LLTCADVECHLLTHV	CRIPAK	86	Q8N1N5
HAEKADVNCACVSHS	EML5	1886	Q05BV3
LADLVHSHIQSNELC	FECH	381	P22830
LVTCHSQEAFENHCA	HELZ2	46	Q9BYK8
MEEELQHSHCVNCVS	FBXO30	1	Q8TB52
RILQLHELVTTHCCN	C9orf57	141	Q5W0N0
ECRVDITLEALHCQH	DLEC1	926	Q9Y238
GHCSQVSCESLLHEV	SCAPER	1256	Q9BY12
SLCVCHGVAVRSNQH	RYR2	616	Q92736
CTLCHERLEDTHFVQ	IRF2BP2	506	Q7Z5L9
ADASHCIHQILESVN	CAMK2G	111	Q13555
FLTHVLNTHCQTCHV	DRD3	346	P35462
CIQQILESVNHCHLN	CAMK2D	116	Q13557
ECHSVQSQDISSCHR	PRR14L	776	Q5THK1
ECCIEVINNTTVQLH	KIF23	41	Q02241
TTSVLCDIHCEANQE	OTOG	2731	Q6ZRI0
SHLQCLSVHCTDDVG	MN1	1276	Q10571
CVAAHHCNQVETESV	LY6G6D	71	O95868
SCENIHLHSEAVLCT	MET	881	P08581
HDSHVCNSLLVAESE	SZT2	1976	Q5T011
DQEAVCLICAISHTH	TRIM39	121	Q9HCM9
FLHHCSCEVKQQLTL	TOP6BL	446	Q8N6T0
LEFTQSHLVCLCQRH	SCPEP1	286	Q9HB40
LELVASLCQQHDVVC	KYAT1	196	Q16773
SLCQQHDVVCITDEV	KYAT1	201	Q16773
LHQHVVKCTVCNEAT	PIP4P2	71	Q8N4L2
CDHVTRSTCHLQKVE	NLRP7	696	Q8WX94
HHSRIISCANCAENE	PLA2G6	136	O60733
HCELQPHCEQAESQV	STARD9	1296	Q9P2P6
SNISHDTVLQCHFTC	ICAM2	81	P13598
CCELEELQHHRQVSE	CCDC136	321	Q96JN2
HCTQCQVLHLPTQEA	ERVK-25	621	P63136
ELSCTTELLILAHHC	SPG11	2111	Q96JI7
CEKVCNRHSSLIQHQ	ZNF667	391	Q5HYK9
RTHNIENAHVCSECG	ZNF615	196	Q8N8J6
HDQEFISCLAHCLIN	WDFY3	2136	Q8IZQ1
GLSHCHALATCVNVV	UMOD	116	P07911
CSQDLLQHHADLTCT	MITF	431	O75030
VVAQSSQEVHHAHCL	UBA7	276	P41226
HHQCSIHLNCEDTLL	PYROXD2	401	Q8N2H3
SHAIFTIHVCQTRVC	KIF21A	226	Q7Z4S6
DDAVQTKQHHSCCIT	TTYH2	76	Q9BSA4
QTLICDVHSITSDNH	SUPT20H	171	Q8NEM7
GSEIKCHSCVHLQSE	ZDBF2	1451	Q9HCK1
CHSCVHLQSEVDQPQ	ZDBF2	1456	Q9HCK1
VINIIHSLCTCSQLH	NF1	2126	P21359
DGELCQEINSCLIHH	STAB1	1491	Q9NY15
HCCEEQVLTLATEQT	POPDC2	131	Q9HBU9
DCVLAVACQQLRIHS	TBCC	251	Q15814
RLCCQNHPETHTLVS	ZNFX1	1261	Q9P2E3
HVDLLTGNCKVCETH	ZBTB39	366	O15060
VSVNNVTHKLCSNHC	ZMYM5	351	Q9UJ78
QLCVVCREAGEHATH	TRIM10	116	Q9UDY6
QRTHEIEKNHVCSEC	ZNF432	196	O94892
FTHLNSHTEVTACEC	ZNF484	211	Q5JVG2
QDCCQEHSGHTIVSL	TRIM16	151	O95361
HCTQCQVLHLPTQEA	ERVK-19	626	Q9WJR5
SQALQEHRLCNDHSC	THSD7B	646	Q9C0I4
VCATHLCSECSQVTH	TRIM23	141	P36406
SSCQELVENCAVHVA	ZNF652	6	Q9Y2D9
QCETAFSQHLHLVCK	ZNF559	151	Q9BR84
SARVQHCICSVASDH	WDR7	526	Q9Y4E6
HQHSQCQDCKDSLSE	ZFYVE26	516	Q68DK2
TVGCCSLRVEHINLH	TOP1	501	P11387
ICCHSLKLLHITDNN	TBCEL	171	Q5QJ74
QHAHVIEDLHCNLCN	ZDHHC1	126	Q8WTX9
IEDLHCNLCNVDVSA	ZDHHC1	131	Q8WTX9
TLTCRDCQLNAHKDH	TRIM28	226	Q13263
LVHQESKTHQCLHCD	ZFY	621	P08048
LHAVADIHCENCKTT	YPEL3	71	P61236
SLALHRCCVELLHNE	UGT1A4	121	P22310
CDDHHCSALLDVSQV	ZBED4	761	O75132
LQCVDLHVISNDVCA	KLK3	171	P07288