Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	retinoic acid binding	UGT1A4 UGT1A3 UGT1A5	8.01e-05	28	60	3	GO:0001972
GeneOntologyMolecularFunction	glucuronosyltransferase activity	UGT1A4 UGT1A3 UGT1A5	1.58e-04	35	60	3	GO:0015020
GeneOntologyMolecularFunction	zinc ion binding	LIMS1 ZNF212 KCMF1 FBXO43 NSD1 ADAMTS20 SLU7 TNFAIP3 RPS29 PDZRN3	2.95e-04	891	60	10	GO:0008270
GeneOntologyMolecularFunction	RNA polymerase II transcription regulatory region sequence-specific DNA binding	HIVEP3 HIVEP2 BBX ZBED4 ZNF212 NSD1 MECOM ZNF229 ZBTB11 ZNF865 PRDM15 KDM6A ZNF440	3.24e-04	1459	60	13	GO:0000977
GeneOntologyMolecularFunction	metallopeptidase activity	NAALAD2 CLCA1 FOLH1 ADAMTS17 ADAMTS20	3.35e-04	200	60	5	GO:0008237
GeneOntologyMolecularFunction	retinoid binding	UGT1A4 UGT1A3 UGT1A5	4.05e-04	48	60	3	GO:0005501
GeneOntologyMolecularFunction	isoprenoid binding	UGT1A4 UGT1A3 UGT1A5	4.31e-04	49	60	3	GO:0019840
GeneOntologyMolecularFunction	peptidase activity	USP36 NAALAD2 CLCA1 USP42 FOLH1 ADAMTS17 ADAMTS20 TNFAIP3	7.22e-04	654	60	8	GO:0008233
GeneOntologyMolecularFunction	cis-regulatory region sequence-specific DNA binding	HIVEP3 HIVEP2 ZNF212 NSD1 MECOM ISL2 ZNF229 ZBTB11 ZNF865 PRDM15 KDM6A	1.27e-03	1271	60	11	GO:0000987
GeneOntologyMolecularFunction	dipeptidase activity	NAALAD2 FOLH1	1.32e-03	18	60	2	GO:0016805
GeneOntologyMolecularFunction	transition metal ion binding	LIMS1 ZNF212 KCMF1 FBXO43 NSD1 ADAMTS20 SLU7 TNFAIP3 RPS29 PDZRN3	2.67e-03	1189	60	10	GO:0046914
GeneOntologyMolecularFunction	DNA-binding transcription factor activity, RNA polymerase II-specific	HIVEP3 HIVEP2 BBX ZBED4 ZNF212 MECOM ISL2 ZNF229 ZBTB11 PRDM15 ZNF440	2.93e-03	1412	60	11	GO:0000981
GeneOntologyBiologicalProcess	cellular glucuronidation	UGT1A4 UGT1A3 UGT1A5	2.85e-05	21	59	3	GO:0052695
GeneOntologyBiologicalProcess	glucuronate metabolic process	UGT1A4 UGT1A3 UGT1A5	5.52e-05	26	59	3	GO:0019585
GeneOntologyBiologicalProcess	uronic acid metabolic process	UGT1A4 UGT1A3 UGT1A5	5.52e-05	26	59	3	GO:0006063
GeneOntologyBiologicalProcess	positive regulation of Wnt signaling pathway	FZD9 RPS12 TNFAIP3 EDA PRDM15	8.88e-05	158	59	5	GO:0030177
HumanPheno	Brachydactyly (hand)	IFT140 ADAMTS17 NSD1 MECOM LTBP2 RPS29 EDA KDM6A	2.13e-06	430	13	8	HP:0100667
HumanPheno	Short finger	IFT140 ADAMTS17 MECOM LTBP2 RPS29 EDA KDM6A	4.96e-06	325	13	7	HP:0009381
HumanPheno	Aplasia/Hypoplasia of fingers	IFT140 ADAMTS17 MECOM LTBP2 RPS29 EDA KDM6A	1.10e-05	366	13	7	HP:0006265
HumanPheno	Iridodonesis	ADAMTS17 LTBP2	5.99e-05	5	13	2	HP:0100693
HumanPheno	Brachydactyly	IFT140 ADAMTS17 NSD1 MECOM LTBP2 RPS29 EDA KDM6A	6.02e-05	670	13	8	HP:0001156
HumanPheno	Short digit	IFT140 ADAMTS17 NSD1 MECOM LTBP2 RPS29 EDA KDM6A	6.16e-05	672	13	8	HP:0011927
HumanPheno	Aplasia/hypoplasia involving bones of the hand	IFT140 ADAMTS17 MECOM LTBP2 RPS29 EDA KDM6A	1.37e-04	538	13	7	HP:0005927
HumanPheno	Intellectual disability, mild	IFT140 ADAMTS17 NSD1 MECOM LTBP2 KDM6A	1.45e-04	365	13	6	HP:0001256
HumanPheno	Aplasia/hypoplasia involving bones of the upper limbs	IFT140 ADAMTS17 MECOM LTBP2 RPS29 EDA KDM6A	2.03e-04	572	13	7	HP:0006496
HumanPheno	Pulmonic stenosis	HIVEP2 ADAMTS17 LTBP2 KDM6A	3.05e-04	138	13	4	HP:0001642
HumanPheno	Hypoplasia of the middle phalanges of the hand	IFT140 MECOM KDM6A	3.16e-04	55	13	3	HP:0010240
HumanPheno	Short middle phalanx of finger	IFT140 MECOM KDM6A	3.16e-04	55	13	3	HP:0005819
HumanPheno	Absent nipple	EDA KDM6A	3.26e-04	11	13	2	HP:0002561
HumanPheno	Neoplasm of the middle ear	NSD1 KDM6A	3.91e-04	12	13	2	HP:0100799
HumanPheno	Phimosis	NSD1 KDM6A	3.91e-04	12	13	2	HP:0001741
HumanPheno	Cholesteatoma	NSD1 KDM6A	3.91e-04	12	13	2	HP:0009797
HumanPheno	Aplasia/Hypoplasia of the middle phalanges of the hand	IFT140 MECOM KDM6A	4.50e-04	62	13	3	HP:0009843
HumanPheno	Ureteral duplication	IFT140 NSD1 KDM6A	5.66e-04	67	13	3	HP:0000073
HumanPheno	Abnormal pulmonary valve physiology	HIVEP2 ADAMTS17 LTBP2 KDM6A	5.76e-04	163	13	4	HP:0031654
Domain	Znf_C2H2	HIVEP3 HIVEP2 ZNF212 KCMF1 ADAMTS17 MECOM ZNF229 ZBTB11 ZNF865 PRDM15 ZNF654 ZNF440	4.48e-06	805	57	12	IPR007087
Domain	ZINC_FINGER_C2H2_2	HIVEP3 HIVEP2 ZNF212 KCMF1 MECOM ZNF229 ZBTB11 ZNF865 PRDM15 ZNF654 ZNF440	1.88e-05	775	57	11	PS50157
Domain	ZINC_FINGER_C2H2_1	HIVEP3 HIVEP2 ZNF212 KCMF1 MECOM ZNF229 ZBTB11 ZNF865 PRDM15 ZNF654 ZNF440	1.93e-05	777	57	11	PS00028
Domain	Znf_C2H2-like	HIVEP3 HIVEP2 ZNF212 KCMF1 MECOM ZNF229 ZBTB11 ZNF865 PRDM15 ZNF654 ZNF440	2.41e-05	796	57	11	IPR015880
Domain	ZnF_C2H2	HIVEP3 HIVEP2 ZNF212 KCMF1 MECOM ZNF229 ZBTB11 ZNF865 PRDM15 ZNF654 ZNF440	2.77e-05	808	57	11	SM00355
Domain	UDPGT	UGT1A4 UGT1A3 UGT1A5	3.45e-05	21	57	3	PF00201
Domain	UDPGT	UGT1A4 UGT1A3 UGT1A5	3.45e-05	21	57	3	PS00375
Domain	UDP_glucos_trans	UGT1A4 UGT1A3 UGT1A5	3.45e-05	21	57	3	IPR002213
Domain	-	HIVEP3 HIVEP2 ZNF212 MECOM ZNF229 ZBTB11 ZNF865 PRDM15 ZNF654 ZNF440	3.48e-05	679	57	10	3.30.160.60
Domain	Znf_C2H2/integrase_DNA-bd	HIVEP3 HIVEP2 ZNF212 MECOM ZNF229 ZBTB11 ZNF865 PRDM15 ZNF654 ZNF440	4.18e-05	694	57	10	IPR013087
Domain	LIM	LIMS1 WTIP ISL2 LMO4	5.81e-05	69	57	4	PF00412
Domain	-	LIMS1 WTIP ISL2 LMO4	6.15e-05	70	57	4	2.10.110.10
Domain	Znf_LIM	LIMS1 WTIP ISL2 LMO4	6.50e-05	71	57	4	IPR001781
Domain	LIM_DOMAIN_1	LIMS1 WTIP ISL2 LMO4	6.50e-05	71	57	4	PS00478
Domain	LIM_DOMAIN_2	LIMS1 WTIP ISL2 LMO4	6.50e-05	71	57	4	PS50023
Domain	LIM	LIMS1 WTIP ISL2 LMO4	6.50e-05	71	57	4	SM00132
Domain	TFR_dimer	NAALAD2 FOLH1	1.36e-04	6	57	2	PF04253
Domain	-	NAALAD2 FOLH1	1.36e-04	6	57	2	1.20.930.40
Domain	TFR-like_dimer_dom	NAALAD2 FOLH1	1.90e-04	7	57	2	IPR007365
Domain	zf-C2H2	HIVEP3 HIVEP2 ZNF212 MECOM ZNF229 ZBTB11 ZNF865 PRDM15 ZNF440	2.31e-04	693	57	9	PF00096
Domain	EGF_CA	SCUBE1 OIT3 ADGRE4P LTBP2	2.37e-04	99	57	4	PS01187
Domain	ASX_HYDROXYL	SCUBE1 OIT3 ADGRE4P LTBP2	2.46e-04	100	57	4	PS00010
Domain	EGF-type_Asp/Asn_hydroxyl_site	SCUBE1 OIT3 ADGRE4P LTBP2	3.07e-04	106	57	4	IPR000152
Domain	zf-C2H2_6	ZNF212 MECOM ZNF229 ZBTB11 ZNF865 ZNF440	3.80e-04	314	57	6	PF13912
Domain	EGF-like_Ca-bd_dom	SCUBE1 OIT3 ADGRE4P LTBP2	5.57e-04	124	57	4	IPR001881
Domain	Peptidase_M28	NAALAD2 FOLH1	5.92e-04	12	57	2	IPR007484
Domain	Peptidase_M28	NAALAD2 FOLH1	5.92e-04	12	57	2	PF04389
Domain	PA	NAALAD2 FOLH1	1.51e-03	19	57	2	PF02225
Domain	PA_domain	NAALAD2 FOLH1	1.51e-03	19	57	2	IPR003137
Domain	ADAM_spacer1	ADAMTS17 ADAMTS20	2.22e-03	23	57	2	IPR010294
Domain	ADAM_spacer1	ADAMTS17 ADAMTS20	2.22e-03	23	57	2	PF05986
Domain	EGF_CA	SCUBE1 ADGRE4P LTBP2	2.31e-03	86	57	3	PF07645
Domain	Peptidase_M12B_ADAM-TS	ADAMTS17 ADAMTS20	2.42e-03	24	57	2	IPR013273
Domain	EGF_Ca-bd_CS	SCUBE1 OIT3 LTBP2	3.24e-03	97	57	3	IPR018097
Domain	EGF_3	SCUBE1 OIT3 ADGRE4P LTBP2	5.73e-03	235	57	4	PS50026
Domain	EGF	SCUBE1 OIT3 ADGRE4P LTBP2	5.73e-03	235	57	4	SM00181
Domain	EGF_CA	SCUBE1 OIT3 LTBP2	6.16e-03	122	57	3	SM00179
Domain	Peptidase_M12B_N	ADAMTS17 ADAMTS20	6.31e-03	39	57	2	IPR002870
Domain	Pep_M12B_propep	ADAMTS17 ADAMTS20	6.31e-03	39	57	2	PF01562
Domain	DISINTEGRIN_1	ADAMTS17 ADAMTS20	6.63e-03	40	57	2	PS00427
Domain	Reprolysin	ADAMTS17 ADAMTS20	6.63e-03	40	57	2	PF01421
Domain	ADAM_MEPRO	ADAMTS17 ADAMTS20	6.63e-03	40	57	2	PS50215
Domain	DISINTEGRIN_2	ADAMTS17 ADAMTS20	6.63e-03	40	57	2	PS50214
Domain	Peptidase_M12B	ADAMTS17 ADAMTS20	6.63e-03	40	57	2	IPR001590
Domain	Disintegrin_dom	ADAMTS17 ADAMTS20	6.95e-03	41	57	2	IPR001762
Domain	EGF-like_dom	SCUBE1 OIT3 ADGRE4P LTBP2	7.01e-03	249	57	4	IPR000742
Domain	SET	NSD1 PRDM15	8.69e-03	46	57	2	SM00317
Domain	SET_dom	NSD1 PRDM15	1.02e-02	50	57	2	IPR001214
Domain	SET	NSD1 PRDM15	1.02e-02	50	57	2	PS50280
Pathway	REACTOME_ATORVASTATIN_ADME	UGT1A4 UGT1A3 UGT1A5	1.01e-05	15	41	3	MM15697
Pathway	REACTOME_HEME_DEGRADATION	UGT1A4 UGT1A3 UGT1A5	2.52e-05	20	41	3	MM14721
Pathway	REACTOME_PREDNISONE_ADME	UGT1A4 UGT1A3 UGT1A5	3.88e-05	23	41	3	MM16639
Pathway	REACTOME_GLUCURONIDATION	UGT1A4 UGT1A3 UGT1A5	4.43e-05	24	41	3	MM14599
Pathway	REACTOME_GLUCURONIDATION	UGT1A4 UGT1A3 UGT1A5	5.02e-05	25	41	3	M17787
Pathway	WP_GLUCURONIDATION	UGT1A4 UGT1A3 UGT1A5	5.02e-05	25	41	3	MM15820
Pathway	KEGG_ASCORBATE_AND_ALDARATE_METABOLISM	UGT1A4 UGT1A3 UGT1A5	5.02e-05	25	41	3	M605
Pathway	WP_GLUCURONIDATION	UGT1A4 UGT1A3 UGT1A5	5.67e-05	26	41	3	M39404
Pathway	KEGG_PENTOSE_AND_GLUCURONATE_INTERCONVERSIONS	UGT1A4 UGT1A3 UGT1A5	7.11e-05	28	41	3	M19580
Pathway	REACTOME_METABOLISM_OF_PORPHYRINS	UGT1A4 UGT1A3 UGT1A5	1.07e-04	32	41	3	MM14719
Pathway	KEGG_PORPHYRIN_AND_CHLOROPHYLL_METABOLISM	UGT1A4 UGT1A3 UGT1A5	2.25e-04	41	41	3	M7399
Pathway	REACTOME_BETA_DEFENSINS	DEFB128 DEFB104A CCR6	2.60e-04	43	41	3	M565
Pathway	REACTOME_ASPIRIN_ADME	UGT1A4 UGT1A3 UGT1A5	2.78e-04	44	41	3	M45014
Pathway	REACTOME_ASPIRIN_ADME	UGT1A4 UGT1A3 UGT1A5	2.98e-04	45	41	3	MM15694
Pathway	KEGG_DRUG_METABOLISM_OTHER_ENZYMES	UGT1A4 UGT1A3 UGT1A5	4.32e-04	51	41	3	M17726
Pathway	REACTOME_ASPARTATE_AND_ASPARAGINE_METABOLISM	NAALAD2 FOLH1	4.46e-04	11	41	2	M27836
Pathway	KEGG_STARCH_AND_SUCROSE_METABOLISM	UGT1A4 UGT1A3 UGT1A5	4.57e-04	52	41	3	M14171
Pathway	REACTOME_DEFENSINS	DEFB128 DEFB104A CCR6	4.84e-04	53	41	3	M557
Pathway	REACTOME_ASPARTATE_AND_ASPARAGINE_METABOLISM	NAALAD2 FOLH1	5.35e-04	12	41	2	MM15556
Pathway	KEGG_STEROID_HORMONE_BIOSYNTHESIS	UGT1A4 UGT1A3 UGT1A5	5.39e-04	55	41	3	M14933
Pathway	KEGG_RETINOL_METABOLISM	UGT1A4 UGT1A3 UGT1A5	8.41e-04	64	41	3	M9488
Pathway	KEGG_METABOLISM_OF_XENOBIOTICS_BY_CYTOCHROME_P450	UGT1A4 UGT1A3 UGT1A5	1.09e-03	70	41	3	M16794
Pathway	KEGG_DRUG_METABOLISM_CYTOCHROME_P450	UGT1A4 UGT1A3 UGT1A5	1.18e-03	72	41	3	M9257
Pathway	WP_ESTROGEN_METABOLISM	UGT1A3 UGT1A5	1.84e-03	22	41	2	MM15888
Pathway	REACTOME_ANTIMICROBIAL_PEPTIDES	DEFB128 DEFB104A CCR6	2.87e-03	98	41	3	M27627
Pubmed	A genome-wide association study identifies UGT1A1 as a regulator of serum cell-free DNA in young adults: The Cardiovascular Risk in Young Finns Study.	UGT1A4 UGT1A3 UGT1A5	4.07e-07	9	60	3	22511988
Pubmed	A novel complex locus UGT1 encodes human bilirubin, phenol, and other UDP-glucuronosyltransferase isozymes with identical carboxyl termini.	UGT1A4 UGT1A3 UGT1A5	4.07e-07	9	60	3	1339448
Pubmed	Association of SNPs in the UGT1A gene cluster with total bilirubin and mortality in the Diabetes Heart Study.	UGT1A4 UGT1A3 UGT1A5	5.81e-07	10	60	3	23642732
Pubmed	UDP-glucuronosyltransferases.	UGT1A4 UGT1A3 UGT1A5	5.81e-07	10	60	3	11465080
Pubmed	A genome-wide association study for serum bilirubin levels and gene-environment interaction in a Chinese population.	UGT1A4 UGT1A3 UGT1A5	5.81e-07	10	60	3	23371916
Pubmed	A genome-wide association study of total bilirubin and cholelithiasis risk in sickle cell anemia.	UGT1A4 UGT1A3 UGT1A5	5.81e-07	10	60	3	22558097
Pubmed	Common variants in the SLCO1B3 locus are associated with bilirubin levels and unconjugated hyperbilirubinemia.	UGT1A4 UGT1A3 UGT1A5	1.06e-06	12	60	3	19419973
Pubmed	Thirteen UDPglucuronosyltransferase genes are encoded at the human UGT1 gene complex locus.	UGT1A4 UGT1A3 UGT1A5	1.06e-06	12	60	3	11434514
Pubmed	Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst.	HIVEP3 LIMS1 BBX ZBED4 ZNF212 KCMF1 ISL2 LMO4 KDM6A ZNF654	1.14e-06	808	60	10	20412781
Pubmed	UGT1A1 is a major locus influencing bilirubin levels in African Americans.	UGT1A4 UGT1A3 UGT1A5	1.38e-06	13	60	3	22085899
Pubmed	Genome-wide analysis of hepatic lipid content in extreme obesity.	UGT1A4 UGT1A3 UGT1A5	1.38e-06	13	60	3	25246029
Pubmed	Mayo Genome Consortia: a genotype-phenotype resource for genome-wide association studies with an application to the analysis of circulating bilirubin levels.	UGT1A4 UGT1A3 UGT1A5	1.75e-06	14	60	3	21646302
Pubmed	Human UDP-glucuronosyltransferases: metabolism, expression, and disease.	UGT1A4 UGT1A3 UGT1A5	1.75e-06	14	60	3	10836148
Pubmed	Multiple variable first exons: a mechanism for cell- and tissue-specific gene regulation.	UGT1A4 UGT1A3 UGT1A5	1.75e-06	14	60	3	14672974
Pubmed	The UDP glycosyltransferase gene superfamily: recommended nomenclature update based on evolutionary divergence.	UGT1A4 UGT1A3 UGT1A5	1.75e-06	14	60	3	9295054
Pubmed	Genome-wide association meta-analysis for total serum bilirubin levels.	UGT1A4 UGT1A3 UGT1A5	2.69e-06	16	60	3	19414484
Pubmed	Cloning and characterization of cDNAs encoding mouse Ugt1.6 and rabbit UGT1.6: differential induction by 2,3,7,8-tetrachlorodibenzo-p-dioxin.	UGT1A3 UGT1A5	2.93e-06	2	60	2	8068691
Pubmed	Two genes encode factors with NF-kappa B- and H2TF1-like DNA-binding properties.	HIVEP3 HIVEP2	2.93e-06	2	60	2	2247438
Pubmed	Human UGT1A4 and UGT1A3 conjugate 25-hydroxyvitamin D3: metabolite structure, kinetics, inducibility, and interindividual variability.	UGT1A4 UGT1A3	2.93e-06	2	60	2	24641623
Pubmed	Structural insight into the evolutionary and pharmacologic homology of glutamate carboxypeptidases II and III.	NAALAD2 FOLH1	2.93e-06	2	60	2	19678840
Pubmed	Uncoupling of growth plate maturation and bone formation in mice lacking both Schnurri-2 and Schnurri-3.	HIVEP3 HIVEP2	2.93e-06	2	60	2	20404140
Pubmed	Influence of a glutamate carboxypeptidase II (GCPII) polymorphism (1561C-->T) on plasma homocysteine, folate and vitamin B(12) levels and its relationship to cardiovascular disease risk.	NAALAD2 FOLH1	2.93e-06	2	60	2	12204797
Pubmed	GCPII and its close homolog GCPIII: from a neuropeptidase to a cancer marker and beyond.	NAALAD2 FOLH1	2.93e-06	2	60	2	30844704
Pubmed	N-glucuronidation of nicotine and cotinine by human liver microsomes and heterologously expressed UDP-glucuronosyltransferases.	UGT1A4 UGT1A3	2.93e-06	2	60	2	14570768
Pubmed	Genome-wide association of serum bilirubin levels in Korean population.	UGT1A4 UGT1A3 UGT1A5	3.26e-06	17	60	3	20639394
Pubmed	A genome-wide assessment of variability in human serum metabolism.	UGT1A4 UGT1A3 UGT1A5	4.64e-06	19	60	3	23281178
Pubmed	The histone demethylase Kdm6b regulates subtype diversification of mouse spinal motor neurons during development.	MECOM ISL2 KDM6A	5.45e-06	20	60	3	35177643
Pubmed	Molecular identification of β-citrylglutamate hydrolase as glutamate carboxypeptidase 3.	NAALAD2 FOLH1	8.77e-06	3	60	2	21908619
Pubmed	Dampening of death pathways by schnurri-2 is essential for T-cell development.	HIVEP3 HIVEP2	8.77e-06	3	60	2	21475200
Pubmed	Isolation and expression of novel human glutamate carboxypeptidases with N-acetylated alpha-linked acidic dipeptidase and dipeptidyl peptidase IV activity.	NAALAD2 FOLH1	8.77e-06	3	60	2	10085079
Pubmed	Biochemical characterization of human glutamate carboxypeptidase III.	NAALAD2 FOLH1	8.77e-06	3	60	2	17241121
Pubmed	Molecular evolution of the transferrin receptor/glutamate carboxypeptidase II family.	NAALAD2 FOLH1	8.77e-06	3	60	2	17160644
Pubmed	Deletion of glutamate carboxypeptidase II (GCPII), but not GCPIII, provided long-term benefits in mice with traumatic brain injury.	NAALAD2 FOLH1	8.77e-06	3	60	2	37349952
Pubmed	Isolation and characterization of a UDP-glucuronosyltransferase (UGT1A01) cloned from female rhesus monkey.	UGT1A3 UGT1A5	8.77e-06	3	60	2	12051676
Pubmed	Human UDP-glucuronosyltransferase (UGT) 2B10 in drug N-glucuronidation: substrate screening and comparison with UGT1A3 and UGT1A4.	UGT1A4 UGT1A3	8.77e-06	3	60	2	23611809
Pubmed	Parallel Metabolomics and Lipidomics of a PSMA/GCPII Deficient Mouse Model Reveal Alteration of NAAG Levels and Brain Lipid Composition.	NAALAD2 FOLH1	8.77e-06	3	60	2	38377674
Pubmed	A role for UDP-glucose glycoprotein glucosyltransferase in expression and quality control of MHC class I molecules.	UGT1A3 UGT1A5	8.77e-06	3	60	2	21383159
Pubmed	Trans-cortical vessels in the mouse temporal bulla bone are a means to recruit myeloid cells in chronic otitis media and limit peripheral leukogram changes.	MECOM EDA	8.77e-06	3	60	2	36246635
Pubmed	Genetic determinants influencing human serum metabolome among African Americans.	UGT1A4 UGT1A3 UGT1A5	9.63e-06	24	60	3	24625756
Pubmed	Control of steroid, heme, and carcinogen metabolism by nuclear pregnane X receptor and constitutive androstane receptor.	UGT1A3 UGT1A5	1.75e-05	4	60	2	12644700
Pubmed	Expression of the UDP-glucuronosyltransferase 1A locus in human colon. Identification and characterization of the novel extrahepatic UGT1A8.	UGT1A4 UGT1A3	1.75e-05	4	60	2	9535849
Pubmed	The EDA-deficient mouse has Zymbal's gland hypoplasia and acute otitis externa.	MECOM EDA	1.75e-05	4	60	2	35107126
Pubmed	Differential expression of the UGT1A locus in human liver, biliary, and gastric tissue: identification of UGT1A7 and UGT1A10 transcripts in extrahepatic tissue.	UGT1A4 UGT1A3	1.75e-05	4	60	2	9271343
Pubmed	Genetic variations and haplotypes of UDP-glucuronosyltransferase 1A locus in a Korean population.	UGT1A4 UGT1A5	1.75e-05	4	60	2	18223459
Pubmed	Ectodysplasin signalling deficiency in mouse models of hypohidrotic ectodermal dysplasia leads to middle ear and nasal pathology.	MECOM EDA	1.75e-05	4	60	2	27378689
Pubmed	Weill-Marchesani Syndrome	ADAMTS17 LTBP2	1.75e-05	4	60	2	20301293
Pubmed	Lhx2 is a direct NF-κB target gene that promotes primary hair follicle placode down-growth.	SCUBE1 TNFAIP3 EDA	2.57e-05	33	60	3	26952977
Pubmed	Limb development genes underlie variation in human fingerprint patterns.	MECOM EDA	2.92e-05	5	60	2	34995520
Pubmed	Keratinocyte-specific ablation of the NF-κB regulatory protein A20 (TNFAIP3) reveals a role in the control of epidermal homeostasis.	TNFAIP3 EDA	2.92e-05	5	60	2	21566665
Pubmed	Variation of hepatic glucuronidation: Novel functional polymorphisms of the UDP-glucuronosyltransferase UGT1A4.	UGT1A4 UGT1A3	2.92e-05	5	60	2	15057901
Pubmed	Isolation of cDNAs for mouse phenol and bilirubin UDP-glucuronosyltransferases and mapping of the mouse gene for phenol UDP-glucuronosyltransferase (Ugtla1) to chromosome 1 by restriction fragment length variations.	UGT1A3 UGT1A5	2.92e-05	5	60	2	7677729
Pubmed	The Nse5/6-like SIMC1-SLF2 complex localizes SMC5/6 to viral replication centers.	USP36 BBX ZC3H4 CDKN2AIP RPS12 NSD1 SLU7 RPS29 DDX1	3.57e-05	954	60	9	36373674
Pubmed	Analysis of inherited genetic variations at the UGT1 locus in the French-Canadian population.	UGT1A4 UGT1A3	4.37e-05	6	60	2	19204906
Pubmed	A regulatory variant in CCR6 is associated with rheumatoid arthritis susceptibility.	CCR6 TNFAIP3	4.37e-05	6	60	2	20453841
Pubmed	Assignment of the human UDP glucuronosyltransferase gene (UGT1A1) to chromosome region 2q37.	UGT1A4 UGT1A5	6.11e-05	7	60	2	8467709
Pubmed	Molecular cloning of two cDNAs encoding the mouse bilirubin/phenol family of UDP-glucuronosyltransferases (mUGTBr/p).	UGT1A3 UGT1A5	6.11e-05	7	60	2	8464825
Pubmed	Maternal epigenetic factors in embryonic and postnatal development.	MECOM KDM6A	6.11e-05	7	60	2	36906847
Pubmed	Simultaneous evaluation of six human glucuronidation activities in liver microsomes using liquid chromatography-tandem mass spectrometry.	UGT1A4 UGT1A3	8.14e-05	8	60	2	22579593
Pubmed	Oligomerization of the UDP-glucuronosyltransferase 1A proteins: homo- and heterodimerization analysis by fluorescence resonance energy transfer and co-immunoprecipitation.	UGT1A4 UGT1A3	8.14e-05	8	60	2	17179145
Pubmed	Alternatively spliced products of the UGT1A gene interact with the enzymatically active proteins to inhibit glucuronosyltransferase activity in vitro.	UGT1A4 UGT1A3	8.14e-05	8	60	2	20610558
Pubmed	Involvement of human UGT2B7 and 2B15 in rofecoxib metabolism.	UGT1A4 UGT1A3	8.14e-05	8	60	2	12695355
Pubmed	A regulatory network to segregate the identity of neuronal subtypes.	ISL2 LMO4	1.05e-04	9	60	2	18539116
Pubmed	Human metabolic individuality in biomedical and pharmaceutical research.	UGT1A4 UGT1A3 UGT1A5	1.34e-04	57	60	3	21886157
Pubmed	Human transcription factor protein interaction networks.	SINHCAF BBX KCMF1 SLU7 MECOM ISL2 RPS29 LMO4 KDM6A DDX1	1.54e-04	1429	60	10	35140242
Pubmed	Role of UDP-glucuronosyltransferase isoforms in 13-cis retinoic acid metabolism in humans.	UGT1A4 UGT1A3	1.91e-04	12	60	2	20308471
Pubmed	Detoxification enzyme polymorphisms are not involved in duodenal adenomatosis in familial adenomatous polyposis.	UGT1A4 UGT1A3	1.91e-04	12	60	2	18161889
Pubmed	Insights on ADAMTS proteases and ADAMTS-like proteins from mammalian genetics.	ADAMTS17 ADAMTS20	1.91e-04	12	60	2	25770910
Pubmed	Genetic variants in TPMT and COMT are associated with hearing loss in children receiving cisplatin chemotherapy.	UGT1A4 UGT1A3 UGT1A5	2.07e-04	66	60	3	19898482
Pubmed	Islet-to-LMO stoichiometries control the function of transcription complexes that specify motor neuron and V2a interneuron identity.	ISL2 LMO4	2.63e-04	14	60	2	19666821
Pubmed	MYC multimers shield stalled replication forks from RNA polymerase.	USP36 SINHCAF USP42 ZC3H4 RPS12 RPS29 ZBTB11 DDX1	2.87e-04	989	60	8	36424410
Pubmed	Interaction network of human early embryonic transcription factors.	HIVEP2 MECOM ISL2 LMO4 KDM6A	3.53e-04	351	60	5	38297188
Pubmed	H4K20me0 recognition by BRCA1-BARD1 directs homologous recombination to sister chromatids.	USP36 SINHCAF BBX ZBED4 USP42 RPS12 NSD1 MECOM KDM6A	3.56e-04	1294	60	9	30804502
Pubmed	Discovery and refinement of loci associated with lipid levels.	UGT1A4 UGT1A3 UGT1A5 ASAP3	4.92e-04	211	60	4	24097068
Pubmed	Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.	LIMS1 SINHCAF ZNF212 ANGEL1 NSD1 SLU7 TNFAIP3 TSTD2	5.28e-04	1084	60	8	11544199
Pubmed	Identification of nine novel loci associated with white blood cell subtypes in a Japanese population.	NAALAD2 LMO4	5.45e-04	20	60	2	21738478
Pubmed	A Cxcl12-CXCR4 chemokine signaling pathway defines the initial trajectory of mammalian motor axons.	ISL2 CCR6	6.02e-04	21	60	2	16129397
Pubmed	Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.	USP36 IFT140 WEE1 ZC3H4 ZNF212 ANGEL1 MECOM PDZRN3	6.39e-04	1116	60	8	31753913
Pubmed	Motor neurons with axial muscle projections specified by Wnt4/5 signaling.	FZD9 ISL2	6.61e-04	22	60	2	19285468
Pubmed	F-box protein FBXL16 binds PP2A-B55α and regulates differentiation of embryonic stem cells along the FLK1+ lineage.	RPS29 DDX1	7.23e-04	23	60	2	24390425
Pubmed	Cloning and enzymatic analysis of 22 novel human ubiquitin-specific proteases.	USP36 USP42	7.23e-04	23	60	2	14715245
Pubmed	Topoisomerase IIβ Selectively Regulates Motor Neuron Identity and Peripheral Connectivity through Hox/Pbx-Dependent Transcriptional Programs.	MECOM ISL2	8.56e-04	25	60	2	29379870
Pubmed	Histone methylation mediated by NSD1 is required for the establishment and maintenance of neuronal identities.	NSD1 LMO4	9.99e-04	27	60	2	37995181
Pubmed	Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation.	NAALAD2 ZC3H4 CDKN2AIP NSD1 ADAMTS20 MECOM TSTD2 PRDM15	1.11e-03	1215	60	8	15146197
Pubmed	Genome-wide association and large-scale follow up identifies 16 new loci influencing lung function.	MECOM DDX1	1.23e-03	30	60	2	21946350
Pubmed	An unexpected role for BAG3 in regulating PARP1 ubiquitination in oxidative stress-related endothelial damage.	RPS29 DDX1	1.32e-03	31	60	2	35066290
Pubmed	OTUD6A Is an Aurora Kinase A-Specific Deubiquitinase.	USP42 TNFAIP3	1.40e-03	32	60	2	33669244
Pubmed	Mass spectrometric analysis of the human 40S ribosomal subunit: native and HCV IRES-bound complexes.	RPS12 RPS29	1.40e-03	32	60	2	15883184
Pubmed	Roles of HIV-1 auxiliary proteins in viral pathogenesis and host-pathogen interactions.	WEE1 DDX1	1.49e-03	33	60	2	16354571
Pubmed	Ubiquitin-specific peptidase 2a (USP2a) deubiquitinates and stabilizes β-catenin.	USP36 TNFAIP3	1.49e-03	33	60	2	30323974
Pubmed	Multiplexed barcoded CRISPR-Cas9 screening enabled by CombiGEM.	NSD1 KDM6A	1.49e-03	33	60	2	26864203
Pubmed	A human MAP kinase interactome.	IFT140 HIVEP2 TNFAIP3 LMO4 ZNF440	1.52e-03	486	60	5	20936779
Pubmed	Tracing the origin of hair follicle stem cells.	ADAMTS17 ADAMTS20	1.68e-03	35	60	2	34108685
Pubmed	Cross-species analysis of the mammalian beta-defensin gene family: presence of syntenic gene clusters and preferential expression in the male reproductive tract.	DEFB128 DEFB104A	1.68e-03	35	60	2	16033865
Pubmed	Meta-analysis of genome-wide association studies of adult height in East Asians identifies 17 novel loci.	ADAMTS17 PLCD4 LTBP2	1.70e-03	136	60	3	25429064
Interaction	MAGEB2 interactions	USP36 BBX USP42 ZC3H4 CDKN2AIP NSD1 ZBTB11 PRDM15	8.72e-06	349	60	8	int:MAGEB2
Cytoband	2q37	UGT1A4 UGT1A3 UGT1A5	9.29e-06	31	60	3	2q37
Cytoband	1p22.3	CLCA1 LMO4	3.82e-04	22	60	2	1p22.3
GeneFamily	Zinc fingers C2H2-type\|ZF class homeoboxes and pseudogenes	HIVEP3 HIVEP2 ZNF212 MECOM ZNF229 ZBTB11 ZNF865 PRDM15 ZNF440	4.75e-05	718	44	9	28
GeneFamily	UDP glucuronosyltransferases	UGT1A4 UGT1A3 UGT1A5	6.35e-05	32	44	3	363
GeneFamily	LIM domain containing	LIMS1 WTIP LMO4	3.97e-04	59	44	3	1218
GeneFamily	Zinc fingers C2H2-type\|PR/SET domain family	MECOM PRDM15	7.69e-04	17	44	2	1197
GeneFamily	ADAM metallopeptidases with thrombospondin type 1 motif	ADAMTS17 ADAMTS20	9.64e-04	19	44	2	50
GeneFamily	S ribosomal proteins	RPS12 RPS29	3.09e-03	34	44	2	728
GeneFamily	Zinc fingers C2H2-type\|Lysine methyltransferases\|PR/SET domain family	NSD1 MECOM	3.09e-03	34	44	2	487
GeneFamily	Defensins, beta	DEFB128 DEFB104A	5.84e-03	47	44	2	503
GeneFamily	Ubiquitin specific peptidases	USP36 USP42	8.20e-03	56	44	2	366
ToppCell	Control-Stromal_mesenchymal-Matrix_Fibroblast-MatrixFB\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	HIVEP3 NAALAD2 FOLH1 ADAMTS17 PDZRN3	4.43e-06	180	60	5	08ae0f5d95c45feba68ad99788f7af7ff4c979af
ToppCell	P03\|World / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	HIVEP3 RPS12 ADAMTS17 RPS29 LMO4	5.06e-06	185	60	5	a07dbe1f76e40734a28826423a5cc64b8e56af5e
ToppCell	Healthy_donor-CD4+_Tcm\|Healthy_donor / disease group, cell group and cell class (v2)	RPS12 CCR6 TNFAIP3 RPS29 EDA	6.22e-06	193	60	5	c16cdd6b439cb8dec228887662ba93d9c7894524
ToppCell	18-Distal-Mesenchymal-Cartilage\|Distal / Age, Tissue, Lineage and Cell class	FZD9 SCUBE1 RPS12 MECOM RPS29	6.22e-06	193	60	5	52f3d1bb8d8ca91ba12439d46392f377928ff8f8
ToppCell	Healthy/Control-CD4+_Tcm\|Healthy/Control / Disease group and Cell class	RPS12 CCR6 TNFAIP3 RPS29 EDA	6.38e-06	194	60	5	08b25c41566d071e079e492cb2c33015b80da72d
ToppCell	3'_v3-blood-Lymphocytic_T_CD4-Teffector/EM_CD4\|blood / Manually curated celltypes from each tissue	USP36 RPS12 CCR6 TNFAIP3 RPS29	6.38e-06	194	60	5	8499c03fa3d5cf9631b128681b13b7fc512b7e63
ToppCell	15-Airway-Mesenchymal-Cartilage\|Airway / Age, Tissue, Lineage and Cell class	FZD9 SCUBE1 RPS12 MECOM RPS29	6.54e-06	195	60	5	414f60bc0f0d0ecb5137bcd617fae91f0c15038a
ToppCell	Sigmoid-(1)_T_cell-(11)_Activated_CD4_T\|Sigmoid / shred on region, Cell_type, and subtype	USP36 RPS12 CCR6 TNFAIP3 RPS29	7.39e-06	200	60	5	ae0597663999deca29f7c0e34256a2b65de0b90b
ToppCell	Sigmoid-T_cell-Activated_CD4_T\|Sigmoid / Region, Cell class and subclass	USP36 RPS12 CCR6 TNFAIP3 RPS29	7.39e-06	200	60	5	b4dd39170890c098df2d3caeb4aa1ff35278b474
ToppCell	(13)_Th17\|World / shred on Cell_type and subtype	LIMS1 RPS12 CCR6 TNFAIP3 RPS29	7.95e-06	203	60	5	e8d5db46093160d403ecd51142c3939d522bca8b
ToppCell	(11)_Activated_CD4_T\|World / shred on Cell_type and subtype	USP36 RPS12 CCR6 TNFAIP3 RPS29	8.14e-06	204	60	5	5c085c5335bf69c18fa298efa137e9bf529eefc6
ToppCell	pdx-Tumor_cells-T9\|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)	LIMS1 SINHCAF WTIP PLCD4	4.27e-05	144	60	4	0b94d978262a826c9254145aa98c6c30240243f9
ToppCell	metastatic_Brain-T/NK_cells-Naive_CD8+_T\|T/NK_cells / Location, Cell class and cell subclass	SCUBE1 RPS12 RPS29 TSPAN32	4.63e-05	147	60	4	4f7a0c287721befeffabf95b8c5f9ff64149c7c1
ToppCell	tumor_Lymph_Node_/_Brain-T/NK_cells-Naive_CD8+_T\|T/NK_cells / Location, Cell class and cell subclass	IFT140 RPS12 ASAP3 RPS29	5.69e-05	155	60	4	1020da8a2c30384d962fa204a030299fdfcbbf98
ToppCell	metastatic_Brain-T/NK_cells-Naive_CD8+_T\|metastatic_Brain / Location, Cell class and cell subclass	SCUBE1 RPS12 RPS29 TSPAN32	5.83e-05	156	60	4	1dcb0b2d1c4b524e692d40e8403dbf7140af19b4
ToppCell	Bac-SEP-Lymphocyte-T_NK-MAIT\|Bac-SEP / Disease, Lineage and Cell Type	EVA1C CCR6 TNFAIP3 RPS29	6.28e-05	159	60	4	e043c65f3febdfa7f75a67702e92fcdebe144a00
ToppCell	Pericytes-Donor_02\|World / lung cells shred on cell class, cell subclass, sample id	SCUBE1 FOLH1 LTBP2 PDZRN3	8.32e-05	171	60	4	bbc8d9fc83d37c9250345b1e76776610799de9ae
ToppCell	facs-Large_Intestine-Distal-18m-Epithelial-epithelial_cell_of_large_intestine\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HIVEP2 CLCA1 WEE1 RPS12	8.70e-05	173	60	4	a5172dee859bf6c2eed46c48bd64dfef0ff9f28f
ToppCell	facs-Large_Intestine-Distal-18m-Epithelial-Lgr5-_amplifying_undifferentiated_cell\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HIVEP2 CLCA1 WEE1 RPS12	8.70e-05	173	60	4	639b5b0b33ce5aa0bc26363c059717012ddc14c0
ToppCell	367C-Lymphocytic-CD4_T-cell-CD4+_Naive_T_cell_/_CD4+_Trm_cell\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	RPS12 CCR6 TNFAIP3 RPS29	8.90e-05	174	60	4	263e6d9c3d59ffc1e88baa1fd20b8c0e5be46ffa
ToppCell	IIF-Lymphocyte-T_NK-CD4_TEM\|IIF / Disease, Lineage and Cell Type	RPS12 CCR6 TNFAIP3 RPS29	9.10e-05	175	60	4	0e7cde3bd638ab85abe915d40c432123f92af4fc
ToppCell	390C-Lymphocytic-CD4_T-cell-Treg_cell_2\|390C / Donor, Lineage, Cell class and subclass (all cells)	HIVEP2 WEE1 CDKN2AIP CCR6	9.72e-05	178	60	4	829ea00c022a78d1861aa3ec53503272976775d9
ToppCell	3'-Child04-06-SmallIntestine-Hematopoietic-T_cells-Th17\|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	RPS12 CCR6 TNFAIP3 RPS29	9.93e-05	179	60	4	61472d75f4a3c4374eeb55ef79982ae4054dadaa
ToppCell	droplet-Lung-30m-Hematologic-myeloid-intermediate_monocyte-intermediate_monocyte_l14\|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	RPS12 ADGRE4P RPS29 LMO4	1.01e-04	180	60	4	05cce7e3c13dd3e3b70aaad841097be51cfadad3
ToppCell	MatrixFB-Fibroblast-A\|MatrixFB / shred on cell class and cell subclass (v4)	HIVEP3 ADAMTS17 RPS29 LMO4	1.01e-04	180	60	4	adc64ad6033af705dd7b9163a83e20ef5c59f6eb
ToppCell	5'-GW_trimst-2-LargeIntestine-Hematopoietic-Myeloid-CLC+_Mast_cell\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ZBED4 TSPAN32 LMO4 PGBD5	1.04e-04	181	60	4	338c7362d258a87f1a6b1a65376f5394d4b2b4b2
ToppCell	367C-Lymphocytic-CD4_T-cell-CD4+_Naive_T_cell_/_CD4+_Trm_cell\|367C / Donor, Lineage, Cell class and subclass (all cells)	RPS12 CCR6 TNFAIP3 RPS29	1.04e-04	181	60	4	9b155a74e68e485039a5195144a12833f2f75058
ToppCell	cellseq-Mesenchymal-Chondrocytic-Mesenchymal_Airway/Vascular\|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	FZD9 NAALAD2 LTBP2 PDZRN3	1.06e-04	182	60	4	bb7de0c93d8f59f13c990e425139b9348ca8027e
ToppCell	cellseq-Mesenchymal-Chondrocytic-Mesenchymal_Airway/Vascular-Chondrocyte\|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	FZD9 NAALAD2 LTBP2 PDZRN3	1.06e-04	182	60	4	507f095af4dff60f2c2b64d750477154084c3595
ToppCell	cellseq-Mesenchymal-Chondrocytic\|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	FZD9 NAALAD2 LTBP2 PDZRN3	1.06e-04	182	60	4	88bd17c07bd8443a0ede4e9dc7bc9d1230b42211
ToppCell	facs-Heart-RA\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RPS12 ADGRE4P TNFAIP3 LMO4	1.06e-04	182	60	4	8292e8e8474c930ffb88cbab4f6ebdb6f58db645
ToppCell	5'-Adult-LargeIntestine-Hematopoietic-T_cells-SELL+_CD8_T\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	RPS12 TNFAIP3 RPS29 TSPAN32	1.10e-04	184	60	4	d5b8604142ae70abbfa4ea881ce55b2a3a2a46a6
ToppCell	droplet-Fat-BAT+GAT+MAT-30m-Lymphocytic-B_cell\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RPS12 CCR6 RPS29 TSPAN32	1.15e-04	186	60	4	0018a949f9f5bfc17f823601303f04dfd56c9a38
ToppCell	3'-Child09-12-SmallIntestine-Hematopoietic-T_cells-Activated_CD4_T\|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	RPS12 CCR6 TNFAIP3 RPS29	1.17e-04	187	60	4	6bdc55213e41346c5914a290b16172cd412ac71d
ToppCell	PCW_13-14-Mesenchymal-Mesenchymal_fibroblastic-mes_immature_COL13A1^pos_fibro2_(5)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	RPS12 ADAMTS17 MECOM LTBP2	1.17e-04	187	60	4	13731298bc562ec29582f5da1b4c97261284f6f1
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	HIVEP3 WEE1 ADAMTS17 MECOM	1.17e-04	187	60	4	77886f99c229610abd28c4c370d2c7d1536c9782
ToppCell	control\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	SINHCAF RPS12 RPS29 SMIM30	1.20e-04	188	60	4	4688de289d60b76245827dc1f71927bdc01b7fb9
ToppCell	metastatic_Brain-T/NK_cells-CD4+_Th\|T/NK_cells / Location, Cell class and cell subclass	RPS12 CCR6 TNFAIP3 EDA	1.20e-04	188	60	4	a23591d917e1fea2b850d5a363001bc698578fa0
ToppCell	wk_15-18-Mesenchymal-Fibroblast-Airway_fibro\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	MECOM LTBP2 LMO4 PDZRN3	1.22e-04	189	60	4	4f9608b84d135268a17455661870c46ae8554a24
ToppCell	metastatic_Brain-T/NK_cells-CD4+_Th\|metastatic_Brain / Location, Cell class and cell subclass	RPS12 CCR6 TNFAIP3 RPS29	1.22e-04	189	60	4	a2b00fbe7b7b15db3fce88a56cbac0ef2917332c
ToppCell	droplet-Kidney-nan-24m-Lymphocytic-CD45____B_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RPS12 CCR6 RPS29 TSPAN32	1.27e-04	191	60	4	04ce9d7a5b5a221576648a6635fe9ec93cbb4ecd
ToppCell	3'-Child09-12-SmallIntestine-Hematopoietic-T_cells-Th17\|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	USP36 CCR6 TNFAIP3 RPS29	1.27e-04	191	60	4	b3ed4797a7a9810cf3507e0d0f23f45c35bd8ba2
ToppCell	droplet-Kidney-nan-18m-Mesenchymal\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NAALAD2 DEFB104A ISL2 LTBP2	1.30e-04	192	60	4	38d7a24ae205ef91ed2e0f402d8022f2a9cdb243
ToppCell	droplet-Lung-21m-Hematologic-lymphocytic-B_cell\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	RPS12 CCR6 RPS29 TSPAN32	1.30e-04	192	60	4	b0686c0676f7658b560967840adb6c182792b075
ToppCell	COVID_non-vent-Lymphocytic-T_cell-CD4+_T_cell_(ISG_high)\|COVID_non-vent / Disease condition, Lineage, Cell class and subclass	USP36 HIVEP2 RPS12 RPS29	1.30e-04	192	60	4	35557254738844c27ffcd00f3287fbcc0a4d0f3b
ToppCell	10x_3'_v3-tissue-resident_(10x_3'_v3)-lymphocytic-B_lymphocytic-B_cell\|tissue-resident_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	SINHCAF WEE1 RPS12 RPS29	1.30e-04	192	60	4	0bda96d8f223e8fa9caf935079ab202fc5c812ee
ToppCell	droplet-Kidney-nan-18m-Mesenchymal-Stroma____fibroblast\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NAALAD2 DEFB104A ISL2 LTBP2	1.30e-04	192	60	4	04d155897ed075c359933080e36a4ab2150b6e9f
ToppCell	390C-Lymphocytic-CD4_T-cell-CD4+_Naive_T_cell_/_CD4+_Trm_cell\|390C / Donor, Lineage, Cell class and subclass (all cells)	RPS12 CCR6 TNFAIP3 RPS29	1.30e-04	192	60	4	494c5eca0f07fc761f26487a2b937c7056bbe594
ToppCell	356C-Lymphocytic-CD4_T-cell-CD4+_Naive_T_cell_/_CD4+_Trm_cell\|356C / Donor, Lineage, Cell class and subclass (all cells)	RPS12 CCR6 TNFAIP3 RPS29	1.30e-04	192	60	4	7aa8585e08dfbee0acbaef5f8f3817ab3ab5af25
ToppCell	droplet-Kidney-nan-24m-Lymphocytic-B_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RPS12 CCR6 RPS29 TSPAN32	1.30e-04	192	60	4	bf0819e99d7bf742c33afad2a0b66a60e1cfb1c2
ToppCell	droplet-Kidney-nan-18m-Mesenchymal-fibroblast\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NAALAD2 DEFB104A ISL2 LTBP2	1.30e-04	192	60	4	84149a5c6c3b3c9b86aed77cf8e72d99ef099fab
ToppCell	Healthy_donor-CD4+_Tcm\|World / disease group, cell group and cell class (v2)	RPS12 CCR6 RPS29 EDA	1.30e-04	192	60	4	1603903454ba6bf65c8e13ede620e0b1e8fbd7ec
ToppCell	356C-Lymphocytic-CD4_T-cell\|356C / Donor, Lineage, Cell class and subclass (all cells)	RPS12 CCR6 TNFAIP3 RPS29	1.30e-04	192	60	4	badf72a52eafb0269391d907ece6b1696684adce
ToppCell	droplet-Lung-21m-Hematologic-lymphocytic-B_cell-B_cell\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	RPS12 CCR6 RPS29 TSPAN32	1.30e-04	192	60	4	7e626ec5a4615e7e04a324937d5f0147dd17ca8e
ToppCell	COPD-Stromal-Myofibroblast\|Stromal / Disease state, Lineage and Cell class	HIVEP3 ADAMTS17 LTBP2 PDZRN3	1.30e-04	192	60	4	62904f94dfce430456f05066522cbf9bd29f4d7e
ToppCell	facs-Tongue-nan-18m-Epithelial-nan\|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HIVEP2 RPS12 RPS29 LMO4	1.33e-04	193	60	4	45361266b5c6e9b229ef80ef692f01b48e5b38ed
ToppCell	10x_3'_v2v3-Non-neoplastic-Lymphoid-CD4/CD8-CD8_EM-G\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	RPS12 CCR6 TNFAIP3 RPS29	1.33e-04	193	60	4	465061688bc09c6d8adc2f662a385dab8918ebbf
ToppCell	Bronchial-10x5prime-Immune_Lymphocytic-T-T_CD8-MAIT\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	USP36 CCR6 TNFAIP3 RPS29	1.33e-04	193	60	4	9aeb34d7a24f84abff38d7b8cf0ec707c08eb27f
ToppCell	facs-Bladder-nan-3m-Epithelial-nan\|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	WEE1 RPS12 MECOM RPS29	1.35e-04	194	60	4	e74cd8cf3763f6adbfd1c269a886a806049714cf
ToppCell	COVID-19_Mild-CD4+_Tcm\|COVID-19_Mild / Disease condition and Cell class	LIMS1 RPS12 CCR6 TNFAIP3	1.35e-04	194	60	4	3be2b1c81e668ffdf593ff41d3ba211c26d77671
ToppCell	normal-na-Lymphocytic_T-T4_em\|normal / PBMC cell types (v2) per disease, treatment status, and sex	RPS12 CCR6 TNFAIP3 RPS29	1.35e-04	194	60	4	cc413fa7d24d0c821ec3a9f6a29ad50203d4fd0d
ToppCell	10x_3'_v2v3-Non-neoplastic-Lymphoid-CD4/CD8-CD8_EM-F\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	RPS12 CCR6 TNFAIP3 RPS29	1.35e-04	194	60	4	cebd6767a1bd656aac2304d29cbbc164850562cc
ToppCell	Healthy/Control-CD4+_Tcm\|World / Disease group and Cell class	RPS12 CCR6 RPS29 EDA	1.35e-04	194	60	4	cbdd1786305108cbeddea07a21120067d78c59a0
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Lymphoid-CD4/CD8-CD8_EM-G\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	CCR6 TNFAIP3 RPS29 TSPAN32	1.35e-04	194	60	4	c49f3341a19128855f084bcf18ef3da4bab79099
ToppCell	356C-Lymphocytic-CD4_T-cell\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	RPS12 CCR6 TNFAIP3 RPS29	1.35e-04	194	60	4	f51760caee571307851c78897789f6e43bac44ae
ToppCell	T/NK_cells-Regulatory_T_cell\|World / Lineage and Cell class	RPS12 CCR6 TNFAIP3 RPS29	1.35e-04	194	60	4	4f55da763f63d1bf6379582e9d85796a797c5b76
ToppCell	T/NK_cells-Regulatory_T_cell\|T/NK_cells / Lineage and Cell class	LIMS1 RPS12 CCR6 TNFAIP3	1.35e-04	194	60	4	22843d03366ead435a0cb35092d6f734c225024c
ToppCell	356C-Lymphocytic-CD4_T-cell-CD4+_Naive_T_cell_/_CD4+_Trm_cell\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	RPS12 CCR6 TNFAIP3 RPS29	1.35e-04	194	60	4	01eab9f799a0bf4af1f2bffedaa1d926d98abe0f
ToppCell	390C-Lymphocytic-CD4_T-cell\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	RPS12 CCR6 TNFAIP3 RPS29	1.35e-04	194	60	4	76c4c3ba5f1bcc39d397c90db3513f5bea632b1b
ToppCell	mild_COVID-19-CD4+_Tcm\|mild_COVID-19 / disease group, cell group and cell class (v2)	RPS12 CCR6 TNFAIP3 RPS29	1.35e-04	194	60	4	cf085813138a73878f9586059cd1d01d1a7ee748
ToppCell	normal-na-Lymphocytic_T-T4_em-female\|normal / PBMC cell types (v2) per disease, treatment status, and sex	RPS12 CCR6 TNFAIP3 RPS29	1.35e-04	194	60	4	29eb99bf3f9f0e2ad61747034b68e8793ad3a701
ToppCell	normal_Lung-T/NK_cells-CD4+_Th\|normal_Lung / Location, Cell class and cell subclass	RPS12 CCR6 TNFAIP3 RPS29	1.38e-04	195	60	4	d6c69f149f3d96fe83f920e38277dede102d04b5
ToppCell	PND10-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF1-AF1_mature\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	HIVEP3 LIMS1 ADAMTS17 LMO4	1.38e-04	195	60	4	1c1135be421af98cd0077bec1ff2c4158d42aa21
ToppCell	5'-Adult-LymphNode-Hematopoietic-T_cells-SELL+_CD8_T\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	RPS12 TNFAIP3 RPS29 TSPAN32	1.38e-04	195	60	4	82561f6ed75ee33c2581fb25bd0997a9f0538cd8
ToppCell	mild_COVID-19-CD4+_Tcm\|World / disease group, cell group and cell class (v2)	RPS12 CCR6 TNFAIP3 RPS29	1.38e-04	195	60	4	fc666cd4d00df9cc03127fb73032ae3e46419055
ToppCell	Mild/Remission-B_memory-0\|World / disease group and sub_cluster of B and Plasma cells(res = 0.5)	SINHCAF RPS12 TNFAIP3 RPS29	1.38e-04	195	60	4	3c51f005d8546c570752f5f0ce6b8ac242d3c54b
ToppCell	mild_COVID-19_(asymptomatic)-CD4+_Tcm\|World / disease group, cell group and cell class (v2)	USP36 CCR6 TNFAIP3 RPS29	1.38e-04	195	60	4	a72bb5b1b15dd1ab70ced5622d94499caff8bb6b
ToppCell	PND10-Mesenchymal-Mesenchymal_structural\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	HIVEP3 LIMS1 ADAMTS17 LMO4	1.38e-04	195	60	4	11d421bbbb71425d59cbdd673e052e00d5f0a768
ToppCell	IIF-Lymphocyte-T_NK-CD4_TCM\|IIF / Disease, Lineage and Cell Type	LIMS1 RPS12 CCR6 RPS29	1.38e-04	195	60	4	8f5d469ef00132637154f6e8847ba4d1e4f008cb
ToppCell	3'-Child04-06-SmallIntestine-Hematopoietic-T_cells-Activated_CD4_T\|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	RPS12 CCR6 TNFAIP3 RPS29	1.38e-04	195	60	4	83dadac78e0dea5cfded82bc67a8f67a2f268ace
ToppCell	systemic_lupus_erythematosus-managed-Lymphocytic_T-T4_em-male\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	RPS12 CCR6 TNFAIP3 RPS29	1.38e-04	195	60	4	48905d57775ec90cc031af0863cc8c3800f2e48e
ToppCell	COVID_non-vent-Lymphocytic-T_cell-CD4+_Memory_T_cell\|COVID_non-vent / Disease condition, Lineage, Cell class and subclass	USP36 HIVEP2 RPS12 RPS29	1.38e-04	195	60	4	22191d361af136942508f1553ff41a626ed982ad
ToppCell	PND10-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF1\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	HIVEP3 LIMS1 ADAMTS17 LMO4	1.38e-04	195	60	4	1f005ee1da66b539bd200aaa98f46edbbc7f12e4
ToppCell	PND10-Mesenchymal-Mesenchymal_structural-Fibroblastic\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	HIVEP3 LIMS1 ADAMTS17 LMO4	1.38e-04	195	60	4	10f307aef8f4d9e71c501d5bcedb84d3be7a4d1b
ToppCell	3'-Pediatric_IBD-SmallIntestine-Hematopoietic-T_cells-Activated_CD4_T\|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract	RPS12 CCR6 TNFAIP3 RPS29	1.38e-04	195	60	4	8ea01038b1e0e038511a3385257ccc8defa110c8
ToppCell	10x5'-Liver-Lymphocytic_T_CD4-Teffector/EM_CD4\|Liver / Manually curated celltypes from each tissue	RPS12 CCR6 TNFAIP3 EDA	1.41e-04	196	60	4	88cafaac9530c648b3ef5ad04b79c7bed8978bb6
ToppCell	PBMC-Convalescent-Lymphocyte-T/NK-CD4+_T-CD4+_Tcm-\|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	LIMS1 RPS12 CCR6 RPS29	1.41e-04	196	60	4	d4fd5513e98eec092d51199e7f054bc15a5eaa3d
ToppCell	PBMC-Convalescent-Lymphocyte-T/NK-CD4+_T-CD4+_Tcm-\|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	LIMS1 RPS12 CCR6 RPS29	1.41e-04	196	60	4	3a08209210e1a8677097a78786e00062c81b1ad2
ToppCell	Multiple_Sclerosis-Lymphocyte-T_NK-CD4_TCM\|Multiple_Sclerosis / Disease, Lineage and Cell Type	LIMS1 RPS12 CCR6 RPS29	1.41e-04	196	60	4	30c31f3d2c1fb3667c5c7f2057eca067dcd69e4d
ToppCell	PBMC-Convalescent-Lymphocyte-T/NK-CD4+_T-CD4+_Tcm\|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	LIMS1 RPS12 CCR6 RPS29	1.41e-04	196	60	4	fddc3e89e7e6b093563655c2d02e86836cfd6da5
ToppCell	COVID-19_Convalescent-CD4+_Tcm\|COVID-19_Convalescent / Disease condition and Cell class	LIMS1 RPS12 CCR6 RPS29	1.41e-04	196	60	4	f2a5eeb1cebde2762865ab29792370b751214c4d
ToppCell	COVID-19_Convalescent-Lymphoid_T/NK-CD4+_Tcm\|COVID-19_Convalescent / Disease group, lineage and cell class	LIMS1 RPS12 CCR6 RPS29	1.41e-04	196	60	4	8caf4334ae692ce44e8fea5d606416afc5b72c00
ToppCell	systemic_lupus_erythematosus-managed-Lymphocytic_T-T4_em-female\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	RPS12 CCR6 TNFAIP3 RPS29	1.41e-04	196	60	4	ea3caea65e8ddd20a837b4322e7940328c94c15a
ToppCell	systemic_lupus_erythematosus-managed-Lymphocytic_T-T4_em\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	RPS12 CCR6 TNFAIP3 RPS29	1.41e-04	196	60	4	f7af0af02059aefb968b72a2a27867ad8ff23614
ToppCell	3'-Pediatric_IBD-SmallIntestine-Hematopoietic-B_cells-GC_B_cell\|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract	HIVEP3 SINHCAF RPS12 RPS29	1.41e-04	196	60	4	d08f6143d148a897efacc854e4306455a9a9868c
ToppCell	healthy_donor-Lymphocytic-T_cell-Gamma_Delta_T_cell\|healthy_donor / Disease condition, Lineage, Cell class and subclass	HIVEP2 RPS12 TNFAIP3 RPS29	1.41e-04	196	60	4	6eabbac1625f715531bae562a28da27664572600
ToppCell	remission-CD4+_Tcm\|remission / disease stage, cell group and cell class	LIMS1 RPS12 CCR6 RPS29	1.41e-04	196	60	4	db7a9669ae35e2c6b465941afef9f7a6b1e7190e
ToppCell	Healthy/Control-CD8+_Tem\|World / Disease group and Cell class	USP36 RPS12 TNFAIP3 RPS29	1.41e-04	196	60	4	a6dc92476156a695e15373ea57dc04e30014ac55
ToppCell	PBMC-Convalescent-Lymphocyte-T/NK-CD4+_T-CD4+_Tcm\|Convalescent / Location, Disease Group, Cell group, Cell class (2021.03.09)	LIMS1 RPS12 CCR6 RPS29	1.41e-04	196	60	4	7d841113a7161b017a08602d46366ac044271b34
ToppCell	tumor_Lung-T/NK_cells-CD4+_Th\|tumor_Lung / Location, Cell class and cell subclass	RPS12 CCR6 TNFAIP3 RPS29	1.41e-04	196	60	4	42f6441505b6f04321da7953d7fe28088b8bdb89
Drug	AC1MRQNQ	UGT1A4 UGT1A3 UGT1A5	1.45e-06	9	60	3	CID003522271
Drug	DHPASiU	UGT1A4 UGT1A3 UGT1A5	1.45e-06	9	60	3	CID000197602
Drug	Chebi:32663	UGT1A4 UGT1A3 UGT1A5	1.45e-06	9	60	3	CID005460873
Drug	3-iodophenol	UGT1A4 UGT1A3 UGT1A5	1.45e-06	9	60	3	CID000012272
Drug	AC1L4J7U	UGT1A4 UGT1A3 UGT1A5	1.45e-06	9	60	3	CID000186631
Drug	4-nitrophenyl)imidazole	UGT1A4 UGT1A3 UGT1A5	2.83e-06	11	60	3	CID000123155
Drug	AC1O5XMV	UGT1A4 UGT1A3 UGT1A5	2.83e-06	11	60	3	CID006442661
Drug	2-methoxyestradiol	UGT1A4 UGT1A3 OIT3 FOLH1 UGT1A5 CCR6 TNFAIP3	2.85e-06	236	60	7	CID000001573
Drug	N-OH-DABZ	UGT1A4 UGT1A3 UGT1A5	3.76e-06	12	60	3	CID000051366
Drug	1-O-beta-D-glucopyranosyl-D-mannitol	UGT1A4 UGT1A3 UGT1A5	3.76e-06	12	60	3	CID000088735
Drug	2,4,6-TCB	UGT1A4 UGT1A3 UGT1A5	3.76e-06	12	60	3	CID000037247
Drug	7,7,7-triphenylheptanoic acid	UGT1A4 UGT1A3 UGT1A5	3.76e-06	12	60	3	CID000276709
Drug	nonanoyl-N-methylglucamide	UGT1A4 UGT1A3 UGT1A5	3.76e-06	12	60	3	CID000160090
Drug	PTBP	UGT1A4 UGT1A3 FOLH1 UGT1A5	4.52e-06	42	60	4	CID000007393
Drug	tritanol	UGT1A4 UGT1A3 UGT1A5	4.88e-06	13	60	3	CID000006457
Drug	5-azido-UDP-glucuronic acid	UGT1A4 UGT1A3 UGT1A5	4.88e-06	13	60	3	CID003081279
Drug	cotinine-N-glucuronide	UGT1A4 UGT1A3 UGT1A5	4.88e-06	13	60	3	CID000000411
Drug	Strophantine octahydrate [11018-89-6]; Up 200; 5.4uM; MCF7; HT_HG-U133A	WEE1 CDKN2AIP TNFAIP3 ZBTB11 KDM6A ZNF654	5.88e-06	171	60	6	5026_UP
Drug	propranolol glucuronide	UGT1A4 UGT1A3 UGT1A5	6.20e-06	14	60	3	CID000119515
Drug	PCB-61	UGT1A4 UGT1A3 UGT1A5	6.20e-06	14	60	3	CID000036401
Drug	afloqualone	UGT1A4 UGT1A3	6.83e-06	2	60	2	ctd:C033541
Drug	2,2',3,5,5'-pentachlorobiphenyl	UGT1A4 UGT1A3 UGT1A5	7.74e-06	15	60	3	CID000040469
Drug	coumarin-3-carboxylic acid	UGT1A4 UGT1A3 UGT1A5	7.74e-06	15	60	3	CID000010752
Drug	sulforaphane nitrile	UGT1A4 UGT1A3 UGT1A5	7.74e-06	15	60	3	CID000543743
Drug	afloqualone	UGT1A4 UGT1A3 UGT1A5	7.74e-06	15	60	3	CID000002040
Drug	naphthyl sulphate	UGT1A4 UGT1A3 UGT1A5	7.74e-06	15	60	3	CID000114775
Drug	quercetin-3,4'-diglucoside	UGT1A4 UGT1A3 UGT1A5	9.51e-06	16	60	3	CID005320835
Drug	1'-hydroxyestragole	UGT1A4 UGT1A3 UGT1A5	9.51e-06	16	60	3	CID000040003
Drug	bilirubin-phosphate	UGT1A4 UGT1A3 UGT1A5	9.51e-06	16	60	3	CID005497144
Drug	propofol	UGT1A4 UGT1A3 OIT3 UGT1A5 TNFAIP3 EDA	1.11e-05	191	60	6	CID000004943
Drug	3 beta,5 alpha,25R)- 3-hydroxyspirostan-12-one	UGT1A4 UGT1A3 UGT1A5	1.15e-05	17	60	3	CID000003573
Drug	6-hydroxychrysene	UGT1A4 UGT1A3 UGT1A5	1.15e-05	17	60	3	CID000037766
Drug	ethyl-beta-D-6-glucosiduronic acid	UGT1A4 UGT1A3 UGT1A5	1.38e-05	18	60	3	CID000152226
Drug	Br 2	UGT1A4 UGT1A3 UGT1A5	1.38e-05	18	60	3	CID003060900
Drug	SureCN12722713	UGT1A4 UGT1A3 UGT1A5	1.38e-05	18	60	3	CID005488034
Drug	2,3,7-trichlorodibenzo-p-dioxin	UGT1A4 UGT1A3 UGT1A5	1.38e-05	18	60	3	CID000036614
Drug	ApApG	UGT1A4 UGT1A3 UGT1A5	1.38e-05	18	60	3	CID003081975
Drug	C1 11-32	UGT1A4 UGT1A3 UGT1A5	1.38e-05	18	60	3	CID000443077
Drug	C11131	UGT1A4 UGT1A3 UGT1A5	1.38e-05	18	60	3	CID000443076
Drug	almokalant	UGT1A4 UGT1A3 UGT1A5	1.64e-05	19	60	3	CID003033962
Drug	9-OH-risperidone	UGT1A4 UGT1A3 UGT1A5	1.64e-05	19	60	3	CID000475100
Drug	5alpha-spirostan-3beta-ol	UGT1A4 UGT1A3 UGT1A5	1.64e-05	19	60	3	CID000091433
Drug	tectochrysin	UGT1A4 UGT1A3 UGT1A5	1.92e-05	20	60	3	CID005281954
Drug	AC1L1OBF	UGT1A4 UGT1A3 UGT1A5	1.92e-05	20	60	3	CID000032736
Drug	4'-hydroxydiclofenac	UGT1A4 UGT1A3 UGT1A5	1.92e-05	20	60	3	CID000116545
Drug	estriol-16-glucuronide	UGT1A4 UGT1A3 UGT1A5	2.24e-05	21	60	3	CID000122281
Drug	dulcin	UGT1A4 UGT1A3 UGT1A5	2.24e-05	21	60	3	CID000009013
Drug	Benzamidoxime hydrochloride	UGT1A4 UGT1A3 UGT1A5	2.24e-05	21	60	3	CID000069186
Drug	amonafide	UGT1A4 UGT1A3 UGT1A5	2.59e-05	22	60	3	CID000050515
Drug	N-methylpiperazine	UGT1A4 UGT1A3 UGT1A5	2.59e-05	22	60	3	CID000053167
Drug	amidoxime	UGT1A4 UGT1A3 UGT1A5	2.97e-05	23	60	3	CID000465967
Drug	estradiol-3-glucuronide	UGT1A4 UGT1A3 UGT1A5	2.97e-05	23	60	3	CID000066651
Drug	phenanthridine	UGT1A4 UGT1A3 UGT1A5	2.97e-05	23	60	3	CID000009189
Drug	AS-3201	UGT1A4 UGT1A3 UGT1A5	3.39e-05	24	60	3	CID000153948
Drug	5-MOP	UGT1A4 UGT1A3 UGT1A5	3.84e-05	25	60	3	CID000002355
Drug	AzMC	UGT1A4 UGT1A3 UGT1A5	3.84e-05	25	60	3	CID000064986
Drug	N-acetylbenzidine	UGT1A4 UGT1A3 UGT1A5	3.84e-05	25	60	3	CID000018787
Drug	5,6-benzoquinoline	UGT1A4 UGT1A3 UGT1A5	3.84e-05	25	60	3	CID000006796
Drug	N-phenylmaleimide	UGT1A4 UGT1A3 UGT1A5	3.84e-05	25	60	3	CID000013662
Drug	DiMeIQx	UGT1A4 UGT1A3 UGT1A5	4.86e-05	27	60	3	CID000104739
Drug	diflunisal	UGT1A4 UGT1A3 UGT1A5	4.86e-05	27	60	3	CID000003059
Drug	16-epiestriol	UGT1A4 UGT1A3 UGT1A5 TNFAIP3	5.11e-05	77	60	4	CID000003269
Drug	8-azaguanine	UGT1A4 UGT1A3 UGT1A5 TNFAIP3	5.37e-05	78	60	4	CID000008646
Drug	N-hydroxy-4-aminobiphenyl	UGT1A4 UGT1A3 UGT1A5	5.44e-05	28	60	3	CID000081261
Drug	CARMINE	UGT1A4 UGT1A3 UGT1A5	5.44e-05	28	60	3	CID000014749
Drug	erucin	UGT1A4 UGT1A3 UGT1A5	5.44e-05	28	60	3	CID000078160
Drug	H-Ni	UGT1A4 UGT1A3 UGT1A5	5.44e-05	28	60	3	CID000445665
Drug	AC1L1JAL	UGT1A4 UGT1A3 UGT1A5	6.05e-05	29	60	3	CID000004954
Drug	7-hydroxy-4-trifluoromethylcoumarin	UGT1A4 UGT1A3 UGT1A5	6.05e-05	29	60	3	CID005375667
Drug	trans-3'-hydroxycotinine	UGT1A4 UGT1A3 UGT1A5	6.05e-05	29	60	3	CID000000414
Drug	7-hydroxycoumarin glucuronide	UGT1A4 UGT1A3 UGT1A5	6.05e-05	29	60	3	CID000125641
Drug	iberin	UGT1A4 UGT1A3 UGT1A5	6.05e-05	29	60	3	CID000010455
Drug	tolcapone	UGT1A4 UGT1A3 UGT1A5	6.71e-05	30	60	3	CID004659569
Drug	paricalcitol	UGT1A4 UGT1A3 UGT1A5	6.71e-05	30	60	3	CID005281104
Drug	AC1L9E0Q	UGT1A4 UGT1A3 UGT1A5	6.71e-05	30	60	3	CID000443095
Drug	dihydroartemisinin	UGT1A4 UGT1A3 UGT1A5	6.71e-05	30	60	3	CID000107770
Drug	Lanatoside C [17575-22-3]; Up 200; 4uM; MCF7; HT_HG-U133A	WEE1 CDKN2AIP TNFAIP3 KDM6A ZNF654	7.23e-05	164	60	5	3963_UP
Drug	4-ethylphenol	UGT1A4 UGT1A3 UGT1A5	7.42e-05	31	60	3	CID000031242
Drug	PCB 156	UGT1A4 UGT1A3 UGT1A5	7.42e-05	31	60	3	CID000038019
Drug	4'-HPPH	UGT1A4 UGT1A3 UGT1A5	7.42e-05	31	60	3	CID000017732
Drug	Digoxin [20830-75-5]; Up 200; 5.2uM; MCF7; HT_HG-U133A	WEE1 CDKN2AIP ZBTB11 KDM6A ZNF654	7.66e-05	166	60	5	5324_UP
Drug	Helveticoside [630-64-8]; Up 200; 7.4uM; MCF7; HT_HG-U133A	WEE1 CDKN2AIP TNFAIP3 KDM6A ZNF654	7.88e-05	167	60	5	6047_UP
Drug	Puromycin dihydrochloride [58-58-2]; Up 200; 7.4uM; MCF7; HT_HG-U133A	HIVEP2 TNFAIP3 KDM6A ZNF654 PGBD5	8.11e-05	168	60	5	5310_UP
Drug	indole-2-carboxylic acid	UGT1A4 UGT1A3 UGT1A5	8.17e-05	32	60	3	CID000072899
Drug	NNAL	UGT1A4 UGT1A3 UGT1A5	8.17e-05	32	60	3	CID000104856
Drug	Muracein C	UGT1A4 UGT1A3 UGT1A5	8.17e-05	32	60	3	CID003086323
Drug	menthol	UGT1A4 UGT1A3 FOLH1 UGT1A5	8.24e-05	87	60	4	CID000001254
Drug	AC1Q6OQG	UGT1A4 UGT1A3 UGT1A5	8.97e-05	33	60	3	CID000009686
Drug	R(-)-Denopamine	UGT1A4 UGT1A3 UGT1A5	8.97e-05	33	60	3	CID000003818
Drug	6-methylsalicylic acid	UGT1A4 UGT1A3 UGT1A5	8.97e-05	33	60	3	CID000011279
Drug	BP-3,6-quinol	UGT1A4 UGT1A3 UGT1A5	8.97e-05	33	60	3	CID000119292
Drug	norbuprenorphine	UGT1A4 UGT1A3 UGT1A5	8.97e-05	33	60	3	CID000114976
Drug	geniposide	UGT1A4 UGT1A3 UGT1A5	8.97e-05	33	60	3	CID000107848
Drug	estragole	UGT1A4 UGT1A3 UGT1A5	9.82e-05	34	60	3	CID000008815
Drug	H944	UGT1A4 UGT1A3 UGT1A5 EDA	1.02e-04	92	60	4	CID000004271
Drug	AC1NOWCJ	UGT1A4 UGT1A3 UGT1A5	1.07e-04	35	60	3	CID005120112
Drug	3-[(3S,5R,10S,13R,14S,17R)-3-[(2S,4R,5R,6S)-4,5-dihydroxy-6-methyloxan-2-yl]oxy-14-hydroxy-10,13-dimethyl-1,2,3,4,5,6,7,8,9,11,12,15,16,17-tetradecahydrocyclopenta[a]phenanthren-17-yl]-2H-furan-5-one	UGT1A4 UGT1A3 UGT1A5	1.07e-04	35	60	3	CID010436171
Drug	estrone-3-glucuronide	UGT1A4 UGT1A3 UGT1A5	1.07e-04	35	60	3	CID000115255
Drug	AC1L9DGV	UGT1A4 UGT1A3 UGT1A5	1.17e-04	36	60	3	CID000417381
Drug	muraglitazar	UGT1A4 UGT1A3 UGT1A5	1.17e-04	36	60	3	CID000206044
Disease	response to dolutegravir	UGT1A4 UGT1A3 UGT1A5 ADGRE4P	3.30e-07	30	57	4	EFO_0600017
Disease	X-11793--oxidized bilirubin measurement	UGT1A4 UGT1A3 UGT1A5	3.80e-07	8	57	3	EFO_0021260
Disease	Succinimide measurement	UGT1A4 UGT1A3 UGT1A5	3.80e-07	8	57	3	EFO_0022118
Disease	X-11530 measurement	UGT1A4 UGT1A3 UGT1A5	3.80e-07	8	57	3	EFO_0021249
Disease	sulfate of piperine metabolite C16H19NO3 (2) measurement	UGT1A4 UGT1A3 UGT1A5	3.80e-07	8	57	3	EFO_0801034
Disease	cholelithiasis, bilirubin measurement	UGT1A4 UGT1A3 UGT1A5	3.80e-07	8	57	3	EFO_0004570, EFO_0004799
Disease	X-11522 measurement	UGT1A4 UGT1A3 UGT1A5	3.80e-07	8	57	3	EFO_0800696
Disease	X-10458 measurement	UGT1A4 UGT1A3 UGT1A5	3.80e-07	8	57	3	EFO_0800692
Disease	X-24849 measurement	UGT1A4 UGT1A3 UGT1A5	3.80e-07	8	57	3	EFO_0800909
Disease	membrane-associated progesterone receptor component 1 measurement	UGT1A4 UGT1A3 UGT1A5	3.80e-07	8	57	3	EFO_0802740
Disease	X-16946 measurement	UGT1A4 UGT1A3 UGT1A5	3.80e-07	8	57	3	EFO_0800766
Disease	X-11442 measurement	UGT1A4 UGT1A3 UGT1A5	5.69e-07	9	57	3	EFO_0021236
Disease	X-11441 measurement	UGT1A4 UGT1A3 UGT1A5	5.69e-07	9	57	3	EFO_0021235
Disease	circulating cell free DNA measurement	UGT1A4 UGT1A3 UGT1A5	5.69e-07	9	57	3	EFO_0004739
Disease	sulfate of piperine metabolite C18H21NO3 (3) measurement	UGT1A4 UGT1A3 UGT1A5	5.69e-07	9	57	3	EFO_0801037
Disease	testis-specific chromodomain protein Y 1 measurement	UGT1A4 UGT1A3 UGT1A5	5.69e-07	9	57	3	EFO_0802127
Disease	sulfate of piperine metabolite C18H21NO3 (1) measurement	UGT1A4 UGT1A3 UGT1A5	5.69e-07	9	57	3	EFO_0801036
Disease	X-11880 measurement	UGT1A4 UGT1A3 UGT1A5	5.69e-07	9	57	3	EFO_0800698
Disease	bilirubin measurement, response to xenobiotic stimulus	UGT1A4 UGT1A3 UGT1A5	5.69e-07	9	57	3	EFO_0004570, GO_0009410
Disease	protein-tyrosine kinase 6 measurement	UGT1A4 UGT1A3 UGT1A5	5.69e-07	9	57	3	EFO_0020691
Disease	X-21448 measurement	UGT1A4 UGT1A3 UGT1A5	8.12e-07	10	57	3	EFO_0800816
Disease	UDP-glucuronosyltransferase 1-6 measurement	UGT1A4 UGT1A3 UGT1A5	8.12e-07	10	57	3	EFO_0802185
Disease	X-23974 measurement	UGT1A4 UGT1A3 UGT1A5	8.12e-07	10	57	3	EFO_0800867
Disease	bilirubin measurement, response to tenofovir	UGT1A4 UGT1A3 UGT1A5	8.12e-07	10	57	3	EFO_0004570, EFO_0009279
Disease	X-21796 measurement	UGT1A4 UGT1A3 UGT1A5	1.12e-06	11	57	3	EFO_0800825
Disease	insomnia, bilirubin measurement	UGT1A4 UGT1A3 UGT1A5	1.12e-06	11	57	3	EFO_0004570, EFO_0004698
Disease	histidine betaine (hercynine) measurement	UGT1A4 UGT1A3 UGT1A5	1.12e-06	11	57	3	EFO_0800972
Disease	aldosterone measurement	UGT1A4 UGT1A3 UGT1A5	1.12e-06	11	57	3	EFO_0010219
Disease	biliverdin measurement	UGT1A4 UGT1A3 UGT1A5	1.49e-06	12	57	3	EFO_0021033
Disease	p-cresol glucuronide measurement	UGT1A4 UGT1A3 UGT1A5	1.49e-06	12	57	3	EFO_0800079
Disease	retinol dehydrogenase 16 measurement	UGT1A4 UGT1A3 UGT1A5	1.93e-06	13	57	3	EFO_0802007
Disease	low density lipoprotein cholesterol measurement, body fat percentage	UGT1A4 UGT1A3 UGT1A5	4.56e-06	17	57	3	EFO_0004611, EFO_0007800
Disease	angiopoietin-related protein 1 measurement	UGT1A4 UGT1A3 UGT1A5	5.46e-06	18	57	3	EFO_0801382
Disease	intraocular pressure measurement	HIVEP3 EVA1C FOLH1 ADAMTS17 ADAMTS20 MECOM LTBP2 EDA	5.84e-06	509	57	8	EFO_0004695
Disease	tissue factor measurement	UGT1A4 UGT1A3 UGT1A5	8.87e-06	21	57	3	EFO_0010623
Disease	hormone measurement	UGT1A4 UGT1A3 ZC3H4 UGT1A5	2.15e-05	84	57	4	EFO_0004730
Disease	Weill-Marchesani syndrome	ADAMTS17 LTBP2	2.19e-05	4	57	2	cv:C0265313
Disease	Weill-Marchesani syndrome (is_implicated_in)	ADAMTS17 LTBP2	2.19e-05	4	57	2	DOID:0050475 (is_implicated_in)
Disease	xanthurenate measurement	UGT1A4 UGT1A3 UGT1A5	2.41e-05	29	57	3	EFO_0010551
Disease	cholelithiasis	UGT1A4 UGT1A3 UGT1A5 NSD1	2.59e-05	88	57	4	EFO_0004799
Disease	urate measurement, spine bone mineral density	UGT1A4 UGT1A3 UGT1A5	1.96e-04	58	57	3	EFO_0004531, EFO_0007701
Disease	pregnenetriol sulfate measurement	UGT1A4 UGT1A5	1.99e-04	11	57	2	EFO_0800586
Disease	plasma N-desmethylclozapine measurement	UGT1A4 UGT1A5	1.99e-04	11	57	2	EFO_0600039
Disease	juvenile polyposis syndrome (implicated_via_orthology)	HIVEP3 HIVEP2	2.82e-04	13	57	2	DOID:0050787 (implicated_via_orthology)
Disease	pregnenetriol disulfate measurement	UGT1A4 UGT1A5	2.82e-04	13	57	2	EFO_0800587
Disease	non-high density lipoprotein cholesterol measurement	UGT1A4 UGT1A3 OIT3 ZC3H4 UGT1A5 ASAP3 NSD1	4.33e-04	713	57	7	EFO_0005689
Disease	X-21441 measurement	UGT1A4 UGT1A5	4.89e-04	17	57	2	EFO_0800814
Disease	thyroxine measurement	UGT1A4 UGT1A3 UGT1A5	5.63e-04	83	57	3	EFO_0005130
Disease	neck circumference	ADAMTS20 PDZRN3	6.14e-04	19	57	2	EFO_0011043
Disease	tooth agenesis	LIMS1 EDA	8.26e-04	22	57	2	EFO_0005410
Disease	gallstones	UGT1A4 UGT1A3 UGT1A5	1.21e-03	108	57	3	EFO_0004210
Disease	Drugs used in diabetes use measurement	SINHCAF HIVEP2 NSD1 LTBP2	1.50e-03	255	57	4	EFO_0009924
Disease	cuneus cortex volume measurement	ADAMTS17 TSPAN32	1.64e-03	31	57	2	EFO_0010301
Disease	apolipoprotein B measurement	UGT1A4 UGT1A3 FZD9 LIMS1 UGT1A5 ZNF229	1.73e-03	663	57	6	EFO_0004615
Disease	CCL2 measurement	HIVEP3 LIMS1 ZC3H4	1.88e-03	126	57	3	EFO_0004749

Protein segments in the cluster

Peptide	Gene	Start	Entry
CAYGYRKCLGKKGRV	UGT1A3	511	P35503
RHYKREAKICTCRGG	nan	6	A8MUN3
NYRLLSCGKILTGCK	ACSBG2	436	Q5FVE4
QKRKCGVKYGCLTIS	ASAP3	321	Q8TDY4
CGSRKSERSCKGALY	BBX	606	Q8WY36
CRNKVGGYICSCLVK	ADGRE4P	71	Q86SQ3
HKARCVYGRVGSVCR	AJM1	706	C9J069
CVRRKYKSSGFSCAG	CCR6	336	P51684
AYLGGVCSAKRKCVL	ADAMTS17	361	Q8TE56
ASCGKGRKYREVFCI	ADAMTS20	1431	P59510
LKLDIKCAYATRGCG	PDZRN3	76	Q9UPQ7
KCAYATRGCGRVVKL	PDZRN3	81	Q9UPQ7
RSLVCGSKVKLCYIG	NSD1	611	Q96L73
RKGKERYTCRYCGKI	MECOM	906	Q03112
KRCAGCGGKIADRFL	LMO4	21	P61968
CSGKIVIARYGKVFR	FOLH1	196	Q04609
GARTKALLGKAVRCY	KDM6A	66	O15550
RCKSVYLGTGCGKSK	CDKN2AIP	506	Q9NXV6
CSSRGKGCYNTRLKE	DDX1	631	Q92499
KNSYRCECGVGRVLR	OIT3	201	Q8WWZ8
EKQGIYCCGLLRARK	PGBD5	356	Q8N414
PYKKRGLCSRTACGF	FBXO43	651	Q4G163
CYRKIAAGRARAKAC	FZD9	541	O00144
CYTAGVCLLKARQKI	EDA	346	Q92838
VLSRRCYGKQRCKII	EVA1C	221	P58658
CKVGERYEIGCLSGK	DEFB128	36	Q7Z7B8
LDRICGYGTARCRKK	DEFB104A	26	Q8WTQ1
GYGTARCRKKCRSQE	DEFB104A	31	Q8WTQ1
CKGKGRCINRVGSYS	LTBP2	896	Q14767
ACLKGNFRGRRYKCL	KCMF1	11	Q9P0J7
CGCRKGYKLLTDERT	SCUBE1	306	Q8IWY4
CYCKVKGLLAAGTDR	IFT140	331	Q96RY7
YVRLFGIKCAKCQVG	ISL2	81	Q96A47
CRVCSNRHGLIRKYG	RPS29	21	P62273
EGYIRALKRGCRCVE	PLCD4	321	Q9BRC7
KYSCKRCQLTFGRGK	PRDM15	991	P57071
ITGICACLGVYARKR	SMIM30	41	A4D0T7
CHNREKARGLGKYIC	LIMS1	121	P48059
YKRRTGCKTDGCAVC	ANGEL1	321	Q9UNK9
VVKKCQGGSCYTKRC	CLCA1	196	A8K7I4
KICCGIIYKGRFGEV	SINHCAF	171	Q9NP50
IHSGERRYKCKICGK	ZNF440	451	Q8IYI8
GYLRSRVKCLNCKGV	USP42	236	Q9H9J4
GSVFKCVKRLDGCIY	WEE1	311	P30291
CVKRLDGCIYAIKRS	WEE1	316	P30291
RKIRKAAACYVVRGG	ZBTB11	31	O95625
KYVHLVRRTLGCGLC	ZNF865	811	P0CJ78
RTGTSKCRKAGCVYF	TNFAIP3	601	P21580
FAIRCGCSLDRKGKY	TSPAN32	221	Q96QS1
RGKYVCEECGIRCKK	HIVEP3	1751	Q5T1R4
KSVKRLRCGKCLTTY	ZNF654	1086	Q8IZM8
CAYGYRKCLGKKGRV	UGT1A5	511	P35504
RKVVGCSCVVVKDYG	RPS12	101	P25398
IITKYRKGACENCGA	SLU7	111	O95391
CERGSAYLKAKGVCK	TSTD2	361	Q5T7W7
KGKVICKYFVEGRCT	ZC3H4	391	Q9UPT8
CDVCGKGFRYKSVLL	ZNF229	351	Q9UJW7
RKSRSSLICGYCGKS	ZNF212	421	Q9UDV6
RTARDYFGICIKCGL	WTIP	216	A6NIX2
RGKYICEECGIRCKK	HIVEP2	1796	P31629
GGYLRSRVKCSVCKS	USP36	246	Q9P275
CAYGYRKCLGKKGRV	UGT1A4	511	P22310
ECRYCGCAISRGKKG	ZBED4	476	O75132
CTGKIVIARYGKIFR	NAALAD2	186	Q9Y3Q0