Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	olfactory receptor activity	OR2C3 OR52E4 OR2J3 OR5B3 OR4C13 OR10A7 OR7E24 OR2H1 OR4C15 OR52Z1P OR4X1 OR4S2 OR4C11 OR4A5 OR4C16 OR2H2 OR1L4 OR2W6P OR2G2	1.67e-24	431	31	19	GO:0004984
GeneOntologyMolecularFunction	G protein-coupled receptor activity	OR2C3 OR52E4 OR2J3 OR5B3 OR4C13 TSHR OR10A7 OR7E24 OR2H1 OR4C15 OR52Z1P OR4X1 OR4S2 OR4C11 OR4A5 OR4C16 OR2H2 OR1L4 OR2W6P OR2G2	3.62e-20	884	31	20	GO:0004930
GeneOntologyMolecularFunction	transmembrane signaling receptor activity	OR2C3 OR52E4 GABRG2 OR2J3 OR5B3 OR4C13 TSHR OR10A7 OR7E24 OR2H1 OR4C15 OR52Z1P OR4X1 OR4S2 OR4C11 OR4A5 OR4C16 OR2H2 OR1L4 OR2W6P OR2G2	5.60e-18	1353	31	21	GO:0004888
GeneOntologyBiologicalProcess	detection of chemical stimulus involved in sensory perception of smell	OR2C3 OR52E4 OR2J3 OR5B3 OR4C13 OR10A7 OR7E24 OR2H1 OR4C15 OR52Z1P OR4X1 OR4S2 OR4C11 OR4A5 OR4C16 OR2H2 OR1L4 OR2W6P OR2G2	2.30e-24	432	32	19	GO:0050911
GeneOntologyBiologicalProcess	sensory perception of smell	OR2C3 OR52E4 OR2J3 OR5B3 OR4C13 OR10A7 OR7E24 OR2H1 OR4C15 OR52Z1P OR4X1 OR4S2 OR4C11 OR4A5 OR4C16 OR2H2 OR1L4 OR2W6P OR2G2	9.40e-24	465	32	19	GO:0007608
GeneOntologyBiologicalProcess	detection of chemical stimulus involved in sensory perception	OR2C3 OR52E4 OR2J3 OR5B3 OR4C13 OR10A7 OR7E24 OR2H1 OR4C15 OR52Z1P OR4X1 OR4S2 OR4C11 OR4A5 OR4C16 OR2H2 OR1L4 OR2W6P OR2G2	2.10e-23	485	32	19	GO:0050907
GeneOntologyBiologicalProcess	detection of chemical stimulus	OR2C3 OR52E4 OR2J3 OR5B3 OR4C13 OR10A7 OR7E24 OR2H1 OR4C15 OR52Z1P OR4X1 OR4S2 OR4C11 OR4A5 OR4C16 OR2H2 OR1L4 OR2W6P OR2G2	9.15e-23	524	32	19	GO:0009593
GeneOntologyBiologicalProcess	sensory perception of chemical stimulus	OR2C3 OR52E4 OR2J3 OR5B3 OR4C13 OR10A7 OR7E24 OR2H1 OR4C15 OR52Z1P OR4X1 OR4S2 OR4C11 OR4A5 OR4C16 OR2H2 OR1L4 OR2W6P OR2G2	2.07e-22	547	32	19	GO:0007606
GeneOntologyBiologicalProcess	detection of stimulus involved in sensory perception	OR2C3 OR52E4 OR2J3 OR5B3 OR4C13 OR10A7 OR7E24 OR2H1 OR4C15 OR52Z1P OR4X1 OR4S2 OR4C11 OR4A5 OR4C16 OR2H2 OR1L4 OR2W6P OR2G2	6.71e-22	582	32	19	GO:0050906
GeneOntologyBiologicalProcess	detection of stimulus	OR2C3 OR52E4 OR2J3 OR5B3 OR4C13 OR10A7 OR7E24 OR2H1 OR4C15 OR52Z1P OR4X1 OR4S2 OR4C11 OR4A5 OR4C16 OR2H2 OR1L4 OR2W6P OR2G2	3.92e-20	722	32	19	GO:0051606
GeneOntologyBiologicalProcess	sensory perception	OR2C3 OR52E4 CLN6 OR2J3 OR5B3 OR4C13 OR10A7 OR7E24 OR2H1 OR4C15 OR52Z1P OR4X1 OR4S2 OR4C11 OR4A5 OR4C16 OR2H2 OR1L4 OR2W6P OR2G2	2.17e-18	1072	32	20	GO:0007600
GeneOntologyBiologicalProcess	G protein-coupled receptor signaling pathway	OR2C3 OR52E4 OR2J3 OR5B3 OR4C13 TSHR OR10A7 OR7E24 OR2H1 OR4C15 OR52Z1P OR4X1 OR4S2 OR4C11 OR4A5 OR4C16 OR2H2 OR1L4 OR2W6P OR2G2	3.63e-16	1395	32	20	GO:0007186
Domain	Olfact_rcpt	OR2C3 OR52E4 OR2J3 OR5B3 OR4C13 OR10A7 OR7E24 OR2H1 OR4C15 OR4X1 OR4S2 OR4C11 OR4A5 OR4C16 OR2H2 OR1L4 OR2G2	9.08e-22	393	29	17	IPR000725
Domain	GPCR_Rhodpsn_7TM	OR2C3 OR52E4 OR2J3 OR5B3 OR4C13 TSHR OR10A7 OR7E24 OR2H1 OR4C15 OR4X1 OR4S2 OR4C11 OR4A5 OR4C16 OR2H2 OR1L4 OR2G2	1.85e-19	670	29	18	IPR017452
Domain	7tm_1	OR2C3 OR52E4 OR2J3 OR5B3 OR4C13 TSHR OR10A7 OR7E24 OR2H1 OR4C15 OR4X1 OR4S2 OR4C11 OR4A5 OR4C16 OR2H2 OR1L4 OR2G2	2.23e-19	677	29	18	PF00001
Domain	G_PROTEIN_RECEP_F1_1	OR2C3 OR52E4 OR2J3 OR5B3 OR4C13 TSHR OR10A7 OR7E24 OR2H1 OR4C15 OR4X1 OR4S2 OR4C11 OR4A5 OR4C16 OR2H2 OR1L4 OR2G2	2.75e-19	685	29	18	PS00237
Domain	G_PROTEIN_RECEP_F1_2	OR2C3 OR52E4 OR2J3 OR5B3 OR4C13 TSHR OR10A7 OR7E24 OR2H1 OR4C15 OR4X1 OR4S2 OR4C11 OR4A5 OR4C16 OR2H2 OR1L4 OR2G2	3.21e-19	691	29	18	PS50262
Domain	GPCR_Rhodpsn	OR2C3 OR52E4 OR2J3 OR5B3 OR4C13 TSHR OR10A7 OR7E24 OR2H1 OR4C15 OR4X1 OR4S2 OR4C11 OR4A5 OR4C16 OR2H2 OR1L4 OR2G2	3.29e-19	692	29	18	IPR000276
Domain	Ion_trans_dom	CACNA1B TRPM3	1.35e-02	114	29	2	IPR005821
Domain	Ion_trans	CACNA1B TRPM3	1.35e-02	114	29	2	PF00520
Pathway	REACTOME_OLFACTORY_SIGNALING_PATHWAY	OR2C3 OR52E4 OR2J3 OR5B3 OR4C13 OR10A7 OR7E24 OR2H1 OR4C15 OR52Z1P OR4X1 OR4S2 OR4C11 OR4A5 OR4C16 OR2H2 OR1L4 OR2G2	2.63e-22	417	26	18	M4072
Pathway	KEGG_OLFACTORY_TRANSDUCTION	OR2C3 OR52E4 OR2J3 OR5B3 OR4C13 OR10A7 OR7E24 OR2H1 OR4C15 OR4X1 OR4S2 OR4C11 OR4A5 OR4C16 OR2H2 OR1L4 OR2G2	5.50e-21	389	26	17	M14091
Pathway	REACTOME_SENSORY_PERCEPTION	OR2C3 OR52E4 OR2J3 OR5B3 OR4C13 OR10A7 OR7E24 OR2H1 OR4C15 OR52Z1P OR4X1 OR4S2 OR4C11 OR4A5 OR4C16 OR2H2 OR1L4 OR2G2	5.29e-19	636	26	18	M41834
Pubmed	The human olfactory receptor gene family.	OR2C3 OR52E4 OR2J3 OR5B3 OR4C13 OR10A7 OR7E24 OR2H1 OR4C15 OR52Z1P OR4X1 OR4S2 OR4C11 OR4A5 OR4C16 OR2H2 OR1L4 OR2W6P OR2G2	2.16e-26	541	33	19	14983052
Pubmed	Different evolutionary processes shaped the mouse and human olfactory receptor gene families.	OR52E4 OR2J3 OR5B3 OR4C13 OR7E24 OR2H1 OR4C15 OR52Z1P OR4S2 OR4C11 OR4A5 OR4C16 OR2H2 OR1L4 OR2W6P	4.62e-22	340	33	15	11875048
Pubmed	The olfactory receptor gene superfamily of the mouse.	OR52E4 OR2J3 OR5B3 OR4C13 OR7E24 OR2H1 OR4C15 OR52Z1P OR4S2 OR4C11 OR4A5 OR4C16 OR2H2 OR1L4 OR2W6P	4.62e-22	340	33	15	11802173
Pubmed	A unified nomenclature for vertebrate olfactory receptors.	OR52E4 OR2J3 OR5B3 OR4C13 OR7E24 OR2H1 OR4C15 OR52Z1P OR4S2 OR4C11 OR4A5 OR4C16 OR2H2 OR1L4 OR2W6P	5.28e-22	343	33	15	32295537
Pubmed	Odorant receptor expressed sequence tags demonstrate olfactory expression of over 400 genes, extensive alternate splicing and unequal expression levels.	OR52E4 OR2J3 OR5B3 OR4C13 OR7E24 OR2H1 OR4C15 OR52Z1P OR4S2 OR4C11 OR4A5 OR4C16 OR2H2 OR1L4 OR2W6P	6.02e-22	346	33	15	14611657
Pubmed	DEFOG: a practical scheme for deciphering families of genes.	OR2C3 OR2J3 OR4C13 OR10A7 OR7E24 OR4S2 OR2H2 OR1L4	2.64e-11	219	33	8	12213199
Pubmed	Complex transcription and splicing of odorant receptor genes.	OR2J3 OR2H1 OR2H2	1.28e-07	11	33	3	12637542
Pubmed	Co-duplication of olfactory receptor and MHC class I genes in the mouse major histocompatibility complex.	OR2J3 OR2H1 OR2H2	2.21e-07	13	33	3	14506126
Pubmed	Odorant and vomeronasal receptor genes in two mouse genome assemblies.	OR4C15 OR4C11 OR4A5 OR4C16	7.37e-07	74	33	4	15081110
Pubmed	Association study of the three functional polymorphisms (TAS2R46G>A, OR4C16G>A, and OR4X1A>T) with recurrent pregnancy loss.	OR4X1 OR4C16	2.62e-06	3	33	2	30203366
Pubmed	A probabilistic classifier for olfactory receptor pseudogenes.	OR2J3 OR4X1 OR4C16	4.99e-06	35	33	3	16939646
Pubmed	Human chromosome 11 DNA sequence and analysis including novel gene identification.	OR52Z1P OR4A5 OR4C16	6.08e-05	80	33	3	16554811
Pubmed	Neuronal ceroid lipofuscinosis (nclf), a new disorder of the mouse linked to chromosome 9.	CLN6 GLO1	7.89e-05	14	33	2	9600738
Pubmed	Patterned expression of ion channel genes in mouse dorsal raphe nucleus determined with the Allen Mouse Brain Atlas.	CACNA1B GABRG2	2.38e-04	24	33	2	22534482
Pubmed	The DNA sequence and analysis of human chromosome 6.	OR2J3 OR2H1 PACRG GLO1 OR2H2	2.82e-04	622	33	5	14574404
Pubmed	The splicing regulator Rbfox2 is required for both cerebellar development and mature motor function.	CACNA1B GABRG2	4.53e-04	33	33	2	22357600
Pubmed	Personal receptor repertoires: olfaction as a model.	OR4X1 OR4C16	6.01e-04	38	33	2	22908908
Pubmed	High-density SNP screening of the major histocompatibility complex in systemic lupus erythematosus demonstrates strong evidence for independent susceptibility regions.	OR2J3 OR2H1 OR2H2	6.11e-04	175	33	3	19851445
Pubmed	Expert curation of the human and mouse olfactory receptor gene repertoires identifies conserved coding regions split across two exons.	OR2J3 OR7E24	8.80e-04	46	33	2	32126975
Cytoband	Ensembl 112 genes in cytogenetic band chr11q11	OR4C15 OR4S2 OR4C11 OR4A5 OR4C16	9.03e-11	40	33	5	chr11q11
Cytoband	11q11	OR4C15 OR4S2 OR4C11 OR4C16	3.86e-08	47	33	4	11q11
Cytoband	Ensembl 112 genes in cytogenetic band chr6p22	OR2J3 OR2H1 OR2H2 OR2W6P	1.53e-04	378	33	4	chr6p22
Cytoband	11p11.12	OR4C13 OR4A5	4.24e-04	42	33	2	11p11.12
Cytoband	1q44	OR2C3 OR2G2	2.86e-03	110	33	2	1q44
Cytoband	Ensembl 112 genes in cytogenetic band chr1q44	OR2C3 OR2G2	3.85e-03	128	33	2	chr1q44
Cytoband	6p22.1	OR2J3 OR2W6P	4.71e-03	142	33	2	6p22.1
Cytoband	Ensembl 112 genes in cytogenetic band chr11p11	OR4C13 OR4X1	5.44e-03	153	33	2	chr11p11
Cytoband	Ensembl 112 genes in cytogenetic band chr9q21	SLC28A3 TRPM3	9.04e-03	199	33	2	chr9q21
Cytoband	11p15.4	OR52E4 OR52Z1P	9.12e-03	200	33	2	11p15.4
GeneFamily	Olfactory receptors, family 4	OR4C13 OR4C15 OR4X1 OR4S2 OR4C11 OR4A5 OR4C16	1.09e-09	129	29	7	151
GeneFamily	Olfactory receptors, family 2	OR2C3 OR2J3 OR2H1 OR2H2 OR2W6P OR2G2	2.20e-08	113	29	6	149
GeneFamily	Olfactory receptors, family 52	OR52E4 OR52Z1P	2.79e-03	49	29	2	165
Disease	Amphetamine Abuse	GABRG2 TRPM3	2.65e-03	75	30	2	C0236807
Disease	Amphetamine Addiction	GABRG2 TRPM3	2.65e-03	75	30	2	C0236804
Disease	Amphetamine-Related Disorders	GABRG2 TRPM3	2.65e-03	75	30	2	C0236733
Disease	Parkinson disease	CACNA1B GABRG2 TMC5	4.17e-03	321	30	3	MONDO_0005180
Disease	R-6-hydroxywarfarin measurement	GABRG2 SLC28A3	6.00e-03	114	30	2	EFO_0803327
Disease	Global developmental delay	CACNA1B TRPM3	8.08e-03	133	30	2	C0557874

Protein segments in the cluster

Peptide	Gene	Start	Entry
MCLYFGSAFATPFLV	COX7C	41	P15954
FYFVSFIFLCSFLML	CACNA1B	1686	Q00975
LFFDGLCEMTFPYEF	PACRG	111	Q96M98
SHICVIFMFYTPAFF	OR52Z1P	226	P0C646
CFYTPAFFSFMTHRF	OR52E4	251	Q8NGH9
MYFFFFFGSSECFLL	OR10A7	101	Q8NGE5
PMYFFLSHLSFLYRC	OR2G2	61	Q8NGZ5
PMYFFLSNLSFLDLC	OR2H2	56	O95918
SPMYFFLGFLSFLDA	OR4C15	56	Q8NGM1
CDFPIMKFSLYFLAY	GLO1	61	Q04760
YFFLANLSFLDMCFT	OR2W6P	66	Q8NHA6
NLFKSPMYFFLSFLS	OR4S2	51	Q8NH73
PMYFFLSFLSFVDIC	OR4S2	56	Q8NH73
PMYFFLSYLSFVEIC	OR4X1	56	Q8NH49
PMYFFLSNLSLVDFC	OR5B3	56	Q8NH48
PMYFFLFYLSFADSC	OR4C11	56	Q6IEV9
PMYFFLAYLSFIDAC	OR4C13	56	Q8NGP0
YFFLANLPFLDMSFT	OR2C3	61	Q8N628
MDSYARIFFPTAFCL	GABRG2	441	P18507
PMFFFLFYLSLSDTC	OR4C16	56	Q8NGL9
AFSPYFKAMFTCGLL	KBTBD12	51	Q3ZCT8
YFFLSNLSFMDICFT	OR1L4	61	Q8NGR5
PMYFFLSDLSFLDLC	OR2H1	56	Q9GZK4
PMYFFLSNLSFLDLC	OR2J3	61	O76001
PMYFFLACLSFIDAA	OR4A5	56	Q8NH83
MSYFPILFFFFLKRC	OR7E24	1	Q6IFN5
SFELICSYIFMPFSF	SLC28A3	481	Q9HAS3
MLFSSLLCVFVAFSY	TRDV1	1	A0A1B0GX56
FLILFMYFSGCFTAS	CLN6	186	Q9NWW5
IMLFFSPLSLSAFYC	TMEM269	206	A0A1B0GVZ9
CLPFFSLDSRLFYSF	TRPM3	326	Q9HCF6
LTTCFFSLLFSMAKY	TMC5	536	Q6UXY8
FTFPFSILFSTFLYC	XKRX	31	Q6PP77
FTDFICMAPISFYAL	TSHR	631	P16473