Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	ABC-type transporter activity	ABCC3 ABCB5 ABCA7 ABCB1 ABCC12 ABCC2	4.70e-07	49	120	6	GO:0140359
GeneOntologyMolecularFunction	ABC-type xenobiotic transporter activity	ABCC3 ABCB5 ABCB1 ABCC2	1.61e-06	15	120	4	GO:0008559
GeneOntologyMolecularFunction	xenobiotic transmembrane transporter activity	ABCC3 ABCB5 ABCB1 ABCC2	5.00e-05	34	120	4	GO:0042910
GeneOntologyMolecularFunction	ATPase-coupled transmembrane transporter activity	ABCC3 ABCB5 ABCA7 ABCB1 ABCC12 ABCC2	5.08e-05	109	120	6	GO:0042626
GeneOntologyMolecularFunction	omega peptidase activity	GGT2P GGT3P UCHL1	1.12e-04	16	120	3	GO:0008242
GeneOntologyMolecularFunction	WW domain binding	TREX1 WBP11 RAPGEF2	4.42e-04	25	120	3	GO:0050699
GeneOntologyMolecularFunction	peptidyltransferase activity	GGT2P GGT3P	5.29e-04	6	120	2	GO:0000048
GeneOntologyMolecularFunction	RNA polymerase III type 3 promoter sequence-specific DNA binding	MAF1 SNAPC4	5.29e-04	6	120	2	GO:0001006
GeneOntologyMolecularFunction	voltage-gated sodium channel activity involved in cardiac muscle cell action potential	SCN2B SCN5A	5.29e-04	6	120	2	GO:0086006
GeneOntologyMolecularFunction	leukotriene-C(4) hydrolase	GGT2P GGT3P	5.29e-04	6	120	2	GO:0002951
GeneOntologyMolecularFunction	primary active transmembrane transporter activity	ABCC3 ABCB5 ABCA7 ABCB1 ABCC12 ABCC2	7.28e-04	178	120	6	GO:0015399
GeneOntologyMolecularFunction	RNA polymerase III cis-regulatory region sequence-specific DNA binding	MAF1 SNAPC4	7.37e-04	7	120	2	GO:0000992
GeneOntologyMolecularFunction	ABC-type glutathione S-conjugate transporter activity	ABCC3 ABCC2	9.79e-04	8	120	2	GO:0015431
GeneOntologyMolecularFunction	leukotriene C4 gamma-glutamyl transferase activity	GGT2P GGT3P	9.79e-04	8	120	2	GO:0103068
GeneOntologyMolecularFunction	RNA polymerase III transcription regulatory region sequence-specific DNA binding	MAF1 SNAPC4	9.79e-04	8	120	2	GO:0001016
GeneOntologyMolecularFunction	phosphatidylcholine floppase activity	ABCA7 ABCB1	9.79e-04	8	120	2	GO:0090554
GeneOntologyMolecularFunction	glutathione hydrolase activity	GGT2P GGT3P	1.25e-03	9	120	2	GO:0036374
GeneOntologyMolecularFunction	ATP hydrolysis activity	ABCC3 SMCHD1 ABCB5 DNAH2 ABCA7 ABCB1 ABCC12 ABCC2 KIF17	1.39e-03	441	120	9	GO:0016887
GeneOntologyMolecularFunction	ATPase-coupled inorganic anion transmembrane transporter activity	ABCC3 ABCC2	1.56e-03	10	120	2	GO:0043225
Domain	ABC_transporter_CS	ABCC3 ABCB5 ABCA7 ABCB1 ABCC12 ABCC2	2.97e-07	42	122	6	IPR017871
Domain	ABC_membrane	ABCC3 ABCB5 ABCB1 ABCC12 ABCC2	4.21e-07	24	122	5	PF00664
Domain	ABC_tran	ABCC3 ABCB5 ABCA7 ABCB1 ABCC12 ABCC2	6.73e-07	48	122	6	PF00005
Domain	ABC_TRANSPORTER_2	ABCC3 ABCB5 ABCA7 ABCB1 ABCC12 ABCC2	6.73e-07	48	122	6	PS50893
Domain	ABC_TRANSPORTER_1	ABCC3 ABCB5 ABCA7 ABCB1 ABCC12 ABCC2	7.63e-07	49	122	6	PS00211
Domain	ABC_transporter-like	ABCC3 ABCB5 ABCA7 ABCB1 ABCC12 ABCC2	8.62e-07	50	122	6	IPR003439
Domain	ABC_TM1F	ABCC3 ABCB5 ABCB1 ABCC12 ABCC2	9.54e-07	28	122	5	PS50929
Domain	ABC1_TM_dom	ABCC3 ABCB5 ABCB1 ABCC12 ABCC2	9.54e-07	28	122	5	IPR011527
Domain	AAA	ABCC3 ABCB5 DNAH2 ABCA7 ABCB1 ABCC12 ABCC2	4.48e-05	144	122	7	SM00382
Domain	AAA+_ATPase	ABCC3 ABCB5 DNAH2 ABCA7 ABCB1 ABCC12 ABCC2	4.48e-05	144	122	7	IPR003593
Domain	Multidrug-R_assoc	ABCC3 ABCC2	2.52e-04	4	122	2	IPR005292
Domain	FG_GAP	ITGA8 CRTAC1 ITGA7	3.82e-04	22	122	3	PS51470
Domain	FG-GAP	ITGA8 CRTAC1 ITGA7	4.98e-04	24	122	3	PF01839
Domain	FG-GAP	ITGA8 CRTAC1 ITGA7	4.98e-04	24	122	3	IPR013517
Domain	GF_recep_IV	PCSK5 EGFR	6.24e-04	6	122	2	PF14843
Domain	GF_recep_IV	PCSK5 EGFR	6.24e-04	6	122	2	IPR032778
Domain	Peptidase_S8_Asp-AS	PCSK5 PCSK2	6.24e-04	6	122	2	IPR023827
Domain	P_proprotein	PCSK5 PCSK2	8.70e-04	7	122	2	PF01483
Domain	S8_pro-domain	PCSK5 PCSK2	8.70e-04	7	122	2	IPR032815
Domain	PrprotnconvertsP	PCSK5 PCSK2	8.70e-04	7	122	2	IPR002884
Domain	-	PCSK5 PCSK2	8.70e-04	7	122	2	3.30.70.850
Domain	S8_pro-domain	PCSK5 PCSK2	8.70e-04	7	122	2	PF16470
Domain	-	PCSK5 PCSK2 HERC2 EPHA1	1.33e-03	73	122	4	2.60.120.260
Domain	Peptidase_S8_His-AS	PCSK5 PCSK2	1.48e-03	9	122	2	IPR022398
Domain	Peptidase_S8_Ser-AS	PCSK5 PCSK2	1.48e-03	9	122	2	IPR023828
Domain	Peptidase_S8_subtilisin-rel	PCSK5 PCSK2	1.84e-03	10	122	2	IPR015500
Domain	SUBTILASE_ASP	PCSK5 PCSK2	1.84e-03	10	122	2	PS00136
Domain	SUBTILASE_HIS	PCSK5 PCSK2	1.84e-03	10	122	2	PS00137
Domain	SUBTILASE_SER	PCSK5 PCSK2	1.84e-03	10	122	2	PS00138
Domain	-	PCSK5 PCSK2	2.24e-03	11	122	2	3.40.50.200
Domain	Peptidase_S8/S53_dom	PCSK5 PCSK2	2.24e-03	11	122	2	IPR000209
Domain	Integrin_alpha	ITGA8 ITGA7	2.24e-03	11	122	2	PF00357
Domain	Peptidase_S8	PCSK5 PCSK2	2.24e-03	11	122	2	PF00082
Domain	PDZ	GOPC PREX2 RAPGEF2 SDCBP PDZD2	2.34e-03	141	122	5	PF00595
Domain	PDZ	GOPC PREX2 RAPGEF2 SDCBP PDZD2	2.88e-03	148	122	5	SM00228
Domain	-	GOPC PREX2 RAPGEF2 SDCBP PDZD2	3.05e-03	150	122	5	2.30.42.10
Domain	PDZ	GOPC PREX2 RAPGEF2 SDCBP PDZD2	3.14e-03	151	122	5	PS50106
Domain	CYTOCHROME_B5_2	SUOX HERC2	3.15e-03	13	122	2	PS50255
Domain	CYTOCHROME_B5_1	SUOX HERC2	3.15e-03	13	122	2	PS00191
Domain	PDZ	GOPC PREX2 RAPGEF2 SDCBP PDZD2	3.23e-03	152	122	5	IPR001478
Domain	Galactose-bd-like	PCSK5 PCSK2 HERC2 EPHA1	3.36e-03	94	122	4	IPR008979
Domain	Cyt-b5	SUOX HERC2	3.66e-03	14	122	2	PF00173
Domain	-	SUOX HERC2	3.66e-03	14	122	2	3.10.120.10
Domain	Cyt_B5-like_heme/steroid-bd	SUOX HERC2	3.66e-03	14	122	2	IPR001199
Domain	Cyt-b5	SUOX HERC2	3.66e-03	14	122	2	SM01117
Domain	SANT	ZSCAN20 MTA3 SNAPC4	4.26e-03	50	122	3	SM00717
Domain	SANT/Myb	ZSCAN20 MTA3 SNAPC4	4.76e-03	52	122	3	IPR001005
Domain	Integrin_alpha_C_CS	ITGA8 ITGA7	4.78e-03	16	122	2	IPR018184
Domain	Propept_inh	PCSK5 PCSK2	5.40e-03	17	122	2	IPR009020
Domain	Integrin_alpha-2	ITGA8 ITGA7	6.05e-03	18	122	2	IPR013649
Domain	INTEGRIN_ALPHA	ITGA8 ITGA7	6.05e-03	18	122	2	PS00242
Domain	Integrin_alpha2	ITGA8 ITGA7	6.05e-03	18	122	2	PF08441
Domain	Integrin_alpha	ITGA8 ITGA7	6.05e-03	18	122	2	IPR000413
Domain	Furin_repeat	PCSK5 EGFR	6.05e-03	18	122	2	IPR006212
Domain	FU	PCSK5 EGFR	6.05e-03	18	122	2	SM00261
Pathway	KEGG_ABC_TRANSPORTERS	ABCC3 ABCB5 ABCA7 ABCB1 ABCC12 ABCC2	3.79e-07	44	92	6	M11911
Pathway	WP_ENTEROHEPATIC_CIRCULATION_OF_BILE_ACIDS	ABCC3 ABCB1 ABCC2	5.67e-05	12	92	3	M48096
Pathway	WP_CODEINE_AND_MORPHINE_METABOLISM	ABCC3 ABCB1 ABCC2	9.29e-05	14	92	3	M39328
Pathway	REACTOME_PARACETAMOL_ADME	ABCC3 GGT2P GGT3P ABCC2	1.17e-04	39	92	4	MM15695
Pathway	WP_DRUG_INDUCTION_OF_BILE_ACID_PATHWAY	ABCC3 ABCB1 ABCC2	1.71e-04	17	92	3	M39666
Pubmed	Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.	USP34 ATXN2L EPPK1 ACLY SMCHD1 INTS1 HNRNPUL1 ANKHD1 TRRAP GTF3C3 SYNE2 YLPM1 ANKRD17 HERC2 EIF3I PHIP SDHA	1.72e-10	653	123	17	22586326
Pubmed	N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.	ATXN2L ACLY SMCHD1 ZNF622 PTPN23 HNRNPUL1 ANKHD1 ADAR EMSY NEK1 RBM12 BAZ1A UCHL1 KIAA1217 YLPM1 ANKRD17 EIF3I HERC4 SDCBP	8.30e-10	934	123	19	33916271
Pubmed	SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.	ATXN2L WDR33 ACLY SMCHD1 PTPN23 ANKHD1 TRRAP ADAR EMSY GTF3C3 NEK1 SH3PXD2B YLPM1	8.29e-08	549	123	13	38280479
Pubmed	TRIM33 drives prostate tumor growth by stabilizing androgen receptor from Skp2-mediated degradation.	USP34 ACLY SMCHD1 HNRNPUL1 TRRAP ADAR RBM12 SF3B3 YLPM1	9.70e-08	220	123	9	35785414
Pubmed	Regulation of mRNA expression of MDR1, MRP1, MRP2 and MRP3 by prototypical microsomal enzyme inducers in primary cultures of human and rat hepatocytes.	ABCC3 ABCB1 ABCC2	1.72e-07	4	123	3	16946557
Pubmed	The Organic Anion-Transporting Peptide 2B1 Is Localized in the Basolateral Membrane of the Human Jejunum and Caco-2 Monolayers.	ABCC3 ABCB1 ABCC2	1.72e-07	4	123	3	28408210
Pubmed	Polymorphisms of the drug transporters ABCB1, ABCG2, ABCC2 and ABCC3 and their impact on drug bioavailability and clinical relevance.	ABCC3 ABCB1 ABCC2	1.72e-07	4	123	3	25162314
Pubmed	Inhibition of tetramethylpyrazine on P-gp, MRP2, MRP3 and MRP5 in multidrug resistant human hepatocellular carcinoma cells.	ABCC3 ABCB1 ABCC2	1.72e-07	4	123	3	19956884
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	PCSK5 USP34 ABCC3 EPPK1 HIVEP2 INTS1 ANKHD1 TRRAP ABCA7 SH3PXD2B SCN5A RIPOR1 HERC2 SNAPC4 SYVN1 CHPF SDHA	3.81e-07	1105	123	17	35748872
Pubmed	Identifying biological pathways that underlie primordial short stature using network analysis.	WBP11 EPPK1 ACLY SMCHD1 INTS1 HNRNPUL1 TRRAP ADAR ABCB1 SF3B3 BAZ1A UCHL1 SYNE2 YLPM1 HERC2 PHIP	7.06e-07	1024	123	16	24711643
Pubmed	A direct physical interaction between Nanog and Sox2 regulates embryonic stem cell self-renewal.	WDR33 INTS1 SALL4 TRRAP EMSY MTA3 KIAA1217	9.40e-07	146	123	7	23892456
Pubmed	Association of multi-drug resistance gene polymorphisms with pancreatic cancer outcome.	ABCC3 ABCB1 ABCC2	1.50e-06	7	123	3	20922799
Pubmed	Tissue distribution and hepatic and renal ontogeny of the multidrug resistance-associated protein (Mrp) family in mice.	ABCC3 ABCC12 ABCC2	2.39e-06	8	123	3	15802388
Pubmed	NANOG-dependent function of TET1 and TET2 in establishment of pluripotency.	SALL4 TRRAP EMSY MTA3	2.45e-06	27	123	4	23395962
Pubmed	Human transcription factor protein interaction networks.	WBP11 WDR33 SMCHD1 HNRNPUL1 ANKHD1 TRRAP ZNF768 EMSY GTF3C3 RBM12 MTA3 SYNE2 YLPM1 MITF USP12 ANKRD17 HERC2 EIF3I	2.93e-06	1429	123	18	35140242
Pubmed	Synthetic Lethal and Resistance Interactions with BET Bromodomain Inhibitors in Triple-Negative Breast Cancer.	USP34 TPT1 WBP11 SMCHD1 INTS1 QRICH1 TRRAP ADAR GTF3C3 RBM12 SF3B3 MTA3 BAZ1A YLPM1 EIF3I	3.15e-06	1014	123	15	32416067
Pubmed	The timing and location of glial cell line-derived neurotrophic factor expression determine enteric nervous system structure and function.	GFRA1 UCHL1 TPH2	3.57e-06	9	123	3	20107080
Pubmed	Shotgun sequencing of the human transcriptome with ORF expressed sequence tags.	CACNA1A GIMAP4 MAF1 DEPDC4 SMCHD1 MUC16 ZBTB41 GGT3P HERC2 FHIP1A PHIP	4.53e-06	552	123	11	10737800
Pubmed	The Functional Proximal Proteome of Oncogenic Ras Includes mTORC2.	ABCC3 GOPC PAK6 ABCB1 LLGL1 CLCN2 EGFR PLCB1 ABCC2 FAM135A EPHA1	6.03e-06	569	123	11	30639242
Pubmed	Dynamic Protein Interactions of the Polycomb Repressive Complex 2 during Differentiation of Pluripotent Cells.	WBP11 SMCHD1 INTS1 SALL4 TRIM21 TRRAP GTF3C3 MTA3 BAZ1A PHIP	6.97e-06	469	123	10	27634302
Pubmed	The Tumor Suppressor CIC Directly Regulates MAPK Pathway Genes via Histone Deacetylation.	EPPK1 SMCHD1 INTS1 TRIM21 GTF3C3 SF3B3 LLGL1 MTA3 BAZ1A EIF3I SDHA	7.58e-06	583	123	11	29844126
Pubmed	The functional interactome landscape of the human histone deacetylase family.	WDR33 ADAR EMSY MTA3 SYNE2 YLPM1 HDAC10 PHIP	9.30e-06	289	123	8	23752268
Pubmed	Targeting USP10 induces degradation of oncogenic ANLN in esophageal squamous cell carcinoma.	ATXN2L EPPK1 ACLY SMCHD1 TRIM21 HNRNPUL1 ADAR ZNF768 GTF3C3 SF3B3 MTA3 EGFR KIAA1217 ANKRD17 EIF3I SDHA	9.65e-06	1257	123	16	36526897
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	ATXN2L HIVEP2 HNRNPUL1 PAK6 NEK1 SH3PXD2B KIAA1217 SYNE2 ANKRD17 NR3C2 EIF3I RAPGEF2 CDK3	1.20e-05	861	123	13	36931259
Pubmed	Quantitative Assessment of the Association between ABC Polymorphisms and Osteosarcoma Response: a Meta-analysis.	ABCC3 ABCB1	1.24e-05	2	123	2	26107220
Pubmed	Effect of ABCB1 and ABCC3 polymorphisms on osteosarcoma survival after chemotherapy: a pharmacogenetic study.	ABCC3 ABCB1	1.24e-05	2	123	2	22016816
Pubmed	UCHL1 Regulates Melanogenesis through Controlling MITF Stability in Human Melanocytes.	UCHL1 MITF	1.24e-05	2	123	2	28392346
Pubmed	Differential effect of P-gp and MRP2 on cellular translocation of gemifloxacin.	ABCB1 ABCC2	1.24e-05	2	123	2	21864659
Pubmed	Genetic polymorphisms of ATP-binding cassette transporters ABCB1 and ABCC2 and their impact on drug disposition.	ABCB1 ABCC2	1.24e-05	2	123	2	21039333
Pubmed	HERC2 rs12913832 modulates human pigmentation by attenuating chromatin-loop formation between a long-range enhancer and the OCA2 promoter.	MITF HERC2	1.24e-05	2	123	2	22234890
Pubmed	Cetuximab directly inhibits P-glycoprotein function in vitro independently of EGFR binding.	ABCB1 EGFR	1.24e-05	2	123	2	25930120
Pubmed	Sal-like 4 protein levels in breast cancer cells are post-translationally down-regulated by tripartite motif-containing 21.	SALL4 TRIM21	1.24e-05	2	123	2	29511085
Pubmed	ABCA7 and EphA1 Genes Polymorphisms in Late-Onset Alzheimer's Disease.	ABCA7 EPHA1	1.24e-05	2	123	2	31659653
Pubmed	Interaction between mineralocorticoid receptor and epidermal growth factor receptor signaling.	EGFR NR3C2	1.24e-05	2	123	2	21827828
Pubmed	UCH-L1-mediated Down-regulation of Estrogen Receptor α Contributes to Insensitivity to Endocrine Therapy for Breast Cancer.	EGFR UCHL1	1.24e-05	2	123	2	32042339
Pubmed	ABCC2 haplotype is not associated with drug-resistant epilepsy.	ABCB1 ABCC2	1.24e-05	2	123	2	18416940
Pubmed	UCH-L1 involved in regulating the degradation of EGFR and promoting malignant properties in drug-resistant breast cancer.	EGFR UCHL1	1.24e-05	2	123	2	26722437
Pubmed	Immunohistochemical Assessment of the Expression of Biliary Transportation Proteins MRP2 and MRP3 in Hepatocellular Carcinoma and in Cholangiocarcinoma.	ABCC3 ABCC2	1.24e-05	2	123	2	29464551
Pubmed	Carcinogen and anticancer drug transport by Mrp2 in vivo: studies using Mrp2 (Abcc2) knockout mice.	ABCB1 ABCC2	1.24e-05	2	123	2	16611851
Pubmed	Dose-dependent disposition of methotrexate in Abcc2 and Abcc3 gene knockout murine models.	ABCC3 ABCC2	1.24e-05	2	123	2	21841039
Pubmed	Aldosterone-induced EGFR expression: interaction between the human mineralocorticoid receptor and the human EGFR promoter.	EGFR NR3C2	1.24e-05	2	123	2	17311890
Pubmed	Llgl1 prevents metaplastic survival driven by epidermal growth factor dependent migration.	LLGL1 EGFR	1.24e-05	2	123	2	27542214
Pubmed	PTPN23[Thr] variant reduces susceptibility and tumorigenesis in esophageal squamous cell carcinoma through dephosphorylation of EGFR.	PTPN23 EGFR	1.24e-05	2	123	2	38704135
Pubmed	The important role of Bcrp (Abcg2) in the biliary excretion of sulfate and glucuronide metabolites of acetaminophen, 4-methylumbelliferone, and harmol in mice.	ABCB1 ABCC2	1.24e-05	2	123	2	16959944
Pubmed	Osimertinib (AZD9291), a Mutant-Selective EGFR Inhibitor, Reverses ABCB1-Mediated Drug Resistance in Cancer Cells.	ABCB1 EGFR	1.24e-05	2	123	2	27649127
Pubmed	RNA editing enzyme ADAR1 governs the circadian expression of P-glycoprotein in human renal cells by regulating alternative splicing of the ABCB1 gene.	ADAR ABCB1	1.24e-05	2	123	2	33781748
Pubmed	Trafficking and localisation to the plasma membrane of Nav 1.5 promoted by the β2 subunit is defective due to a β2 mutation associated with Brugada syndrome.	SCN2B SCN5A	1.24e-05	2	123	2	28597987
Pubmed	Influence of polymorphisms of ABCB1 and ABCC2 on mRNA and protein expression in normal and cancerous kidney cortex.	ABCB1 ABCC2	1.24e-05	2	123	2	16788565
Pubmed	Modulation of MDR1 and MRP3 gene expression in lung cancer cells after paclitaxel and carboplatin exposure.	ABCC3 ABCB1	1.24e-05	2	123	2	23443122
Pubmed	Differential modulation of the human liver conjugate transporters MRP2 and MRP3 by bile acids and organic anions.	ABCC3 ABCC2	1.24e-05	2	123	2	12704183
Pubmed	RANK and EGFR in invasive breast carcinoma.	TNFRSF11A EGFR	1.24e-05	2	123	2	29025596
Pubmed	Altered regulation of hepatic efflux transporters disrupts acetaminophen disposition in pediatric nonalcoholic steatohepatitis.	ABCC3 ABCC2	1.24e-05	2	123	2	25788542
Pubmed	EGFR mediates docetaxel resistance in human castration-resistant prostate cancer through the Akt-dependent expression of ABCB1 (MDR1).	ABCB1 EGFR	1.24e-05	2	123	2	24888374
Pubmed	Expression of the multidrug resistance proteins MRP2 and MRP3 in human hepatocellular carcinoma.	ABCC3 ABCC2	1.24e-05	2	123	2	11745434
Pubmed	The clinical relevance and prognostic significance of adenosine triphosphate ATP-binding cassette (ABCB5) and multidrug resistance (MDR1) genes expression in acute leukemia: an Egyptian study.	ABCB5 ABCB1	1.24e-05	2	123	2	24804815
Pubmed	Effect of variation of ABCB1 and ABCC3 genotypes on the survival of bone tumor cases after chemotherapy.	ABCC3 ABCB1	1.24e-05	2	123	2	24083708
Pubmed	Major glucuronide metabolites of testosterone are primarily transported by MRP2 and MRP3 in human liver, intestine and kidney.	ABCC3 ABCC2	1.24e-05	2	123	2	30959153
Pubmed	Impact of Abcc2 (Mrp2) and Abcc3 (Mrp3) on the in vivo elimination of methotrexate and its main toxic metabolite 7-hydroxymethotrexate.	ABCC3 ABCC2	1.24e-05	2	123	2	19088030
Pubmed	The potential role of human multidrug resistance protein 1 (MDR1) and multidrug resistance-associated protein 2 (MRP2) in the transport of Huperzine A in vitro.	ABCB1 ABCC2	1.24e-05	2	123	2	31132291
Pubmed	Association between the polymorphisms in the ATP-binding cassette genes ABCB1 and ABCC2 and the risk of drug-resistant epilepsy in a Chinese Han population.	ABCB1 ABCC2	1.24e-05	2	123	2	27886333
Pubmed	Linkage disequilibrium between polymorphisms of ABCB1 and ABCC2 to predict the treatment outcome of Malaysians with complex partial seizures on treatment with carbamazepine mono-therapy at the Kuala Lumpur Hospital.	ABCB1 ABCC2	1.24e-05	2	123	2	23717663
Pubmed	The deubiquitinase UCHL1 regulates cardiac hypertrophy by stabilizing epidermal growth factor receptor.	EGFR UCHL1	1.24e-05	2	123	2	32494592
Pubmed	A Multipronged Unbiased Strategy Guides the Development of an Anti-EGFR/EPHA2-Bispecific Antibody for Combination Cancer Therapy.	GOPC ITGA7 LLGL1 EGFR KIAA1217 PLCB1 USP12 FAM135A SDHA	2.00e-05	421	123	9	36976175
Pubmed	Protein interactome mining defines melatonin MT1 receptors as integral component of presynaptic protein complexes of neurons.	USP34 HIVEP2 ABCB5 INTS1 BAZ1A UCHL1 SYNE2 HDAC10	2.03e-05	322	123	8	26514267
Pubmed	The planar cell polarity gene Vangl2 is required for mammalian kidney-branching morphogenesis and glomerular maturation.	ITGA8 GGT2P GGT3P EGFR NR3C2	2.29e-05	95	123	5	20843830
Pubmed	Human Antiviral Protein IFIX Suppresses Viral Gene Expression during Herpes Simplex Virus 1 (HSV-1) Infection and Is Counteracted by Virus-induced Proteasomal Degradation.	WBP11 WDR33 ZNF622 GTF3C3 BAZ1A ANKRD17 EIF3I	3.27e-05	251	123	7	28077445
Pubmed	Tissue-Specific Regulation of the Wnt/β-Catenin Pathway by PAGE4 Inhibition of Tankyrase.	ACLY SMCHD1 TRIM21 HNRNPUL1 ADAR SF3B3 SDHA	3.71e-05	256	123	7	32698014
Pubmed	Disposition of 9-nitrocamptothecin and its 9-aminocamptothecin metabolite in relation to ABC transporter genotypes.	ABCB1 ABCC2	3.71e-05	3	123	2	16505951
Pubmed	Contribution of child ABC-transporter genetics to prenatal MeHg exposure and neurodevelopment.	ABCB1 ABCC2	3.71e-05	3	123	2	35654246
Pubmed	The ABCB1, ABCC2 and RALBP1 polymorphisms are associated with carbamazepine response in epileptic patient: a systematic review.	ABCB1 ABCC2	3.71e-05	3	123	2	35325436
Pubmed	In vivo relevance of Mrp2-mediated biliary excretion of the Amanita mushroom toxin demethylphalloin.	ABCB1 ABCC2	3.71e-05	3	123	2	17707334
Pubmed	Inhibition of P-glycoprotein and multidrug resistance-associated proteins modulates the intracellular concentration of lopinavir in cultured CD4 T cells and primary human lymphocytes.	ABCB1 ABCC2	3.71e-05	3	123	2	17890284
Pubmed	The role of multidrug resistance proteins MRP1, MRP2 and MRP3 in cellular folate homeostasis.	ABCC3 ABCC2	3.71e-05	3	123	2	12628490
Pubmed	Influence of ATP-binding cassette polymorphisms on neurological outcome after traumatic brain injury.	ABCB1 ABCC2	3.71e-05	3	123	2	23896815
Pubmed	Increased multidrug resistance-associated protein activity in mononuclear cells of patients with systemic lupus erythematosus.	ABCC3 ABCC2	3.71e-05	3	123	2	18799096
Pubmed	Common variants in ABCB1, ABCC2 and ABCG2 genes and clinical outcomes among women with advanced stage ovarian cancer treated with platinum and taxane-based chemotherapy: a Gynecologic Oncology Group study.	ABCB1 ABCC2	3.71e-05	3	123	2	22112610
Pubmed	Physiological and pharmacological functions of Mrp2, Mrp3 and Mrp4 as determined from recent studies on gene-disrupted mice.	ABCC3 ABCC2	3.71e-05	3	123	2	17273943
Pubmed	Vectorial transport of fexofenadine across Caco-2 cells: involvement of apical uptake and basolateral efflux transporters.	ABCC3 ABCB1	3.71e-05	3	123	2	21780830
Pubmed	Involvement of multiple efflux transporters in hepatic disposition of fexofenadine.	ABCC3 ABCC2	3.71e-05	3	123	2	18245269
Pubmed	PC1/3, PC2 and PC5/6A are targeted to dense core secretory granules by a common mechanism.	PCSK5 PCSK2	3.71e-05	3	123	2	17645548
Pubmed	EGFR and SYNE2 are associated with p21 expression and SYNE2 variants predict post-operative clinical outcomes in HBV-related hepatocellular carcinoma.	EGFR SYNE2	3.71e-05	3	123	2	27502069
Pubmed	Zinc finger nuclease-mediated gene knockout results in loss of transport activity for P-glycoprotein, BCRP, and MRP2 in Caco-2 cells.	ABCB1 ABCC2	3.71e-05	3	123	2	25388687
Pubmed	Hepatocellular Shuttling and Recirculation of Sorafenib-Glucuronide Is Dependent on Abcc2, Abcc3, and Oatp1a/1b.	ABCC3 ABCC2	3.71e-05	3	123	2	25952649
Pubmed	The cell-specific pattern of cholecystokinin peptides in endocrine cells versus neurons is governed by the expression of prohormone convertases 1/3, 2, and 5/6.	PCSK5 PCSK2	3.71e-05	3	123	2	18096669
Pubmed	Complex pharmacokinetic behavior of ezetimibe depends on abcc2, abcc3, and abcg2.	ABCC3 ABCC2	3.71e-05	3	123	2	19443695
Pubmed	Application of multivariate statistical procedures to identify transcription factors that correlate with MRP2, 3, and 4 mRNA in adult human livers.	ABCC3 ABCC2	3.71e-05	3	123	2	19480556
Pubmed	Absolute immunoquantification of the expression of ABC transporters P-glycoprotein, breast cancer resistance protein and multidrug resistance-associated protein 2 in human liver and duodenum.	ABCB1 ABCC2	3.71e-05	3	123	2	22062654
Pubmed	Abcc2 (Mrp2), Abcc3 (Mrp3), and Abcg2 (Bcrp1) are the main determinants for rapid elimination of methotrexate and its toxic metabolite 7-hydroxymethotrexate in vivo.	ABCC3 ABCC2	3.71e-05	3	123	2	19996279
Pubmed	Population Pharmacokinetics, Pharmacogenomics, and Adverse Events of Osimertinib and its Two Active Metabolites, AZ5104 and AZ7550, in Japanese Patients with Advanced Non-small Cell Lung Cancer: a Prospective Observational Study.	ABCB1 EGFR	3.71e-05	3	123	2	36637703
Pubmed	A comprehensive study of polymorphisms in ABCB1, ABCC2 and ABCG2 and lung cancer chemotherapy response and prognosis.	ABCB1 ABCC2	3.71e-05	3	123	2	22473764
Pubmed	ABC drug transporter and nuclear receptor expression in human cytotrophoblasts: influence of spontaneous syncytialization and induction by glucocorticoids.	ABCB1 ABCC2	3.71e-05	3	123	2	22922069
Pubmed	Telmisartan pharmacokinetics in Japanese renal transplant recipients.	ABCB1 ABCC2	3.71e-05	3	123	2	18838068
Pubmed	Mutational analysis of a highly conserved proline residue in MRP1, MRP2, and MRP3 reveals a partially conserved function.	ABCC3 ABCC2	3.71e-05	3	123	2	17494643
Pubmed	[Expression of ATP-binding Cassette Proteins Pgp, MRP1, and MRP3 in Malignant and Benign Ovarian Lesions].	ABCC3 ABCB1	3.71e-05	3	123	2	27739315
Pubmed	Baicalin positively regulates osteoclast function by activating MAPK/Mitf signalling.	TNFRSF11A MITF	3.71e-05	3	123	2	28158928
Pubmed	CircNR3C2 promotes HRD1-mediated tumor-suppressive effect via sponging miR-513a-3p in triple-negative breast cancer.	NR3C2 SYVN1	3.71e-05	3	123	2	33530981
Pubmed	ABCB5 is activated by MITF and β-catenin and is associated with melanoma differentiation.	ABCB5 MITF	3.71e-05	3	123	2	31595650
Pubmed	Bcrp1;Mdr1a/b;Mrp2 combination knockout mice: altered disposition of the dietary carcinogen PhIP (2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine) and its genotoxic metabolites.	ABCB1 ABCC2	3.71e-05	3	123	2	24334255
Pubmed	Polymorphisms in drug transporter genes (ABCB1, SLCO1B1 and ABCC2) and hepatitis induced by antituberculosis drugs.	ABCB1 ABCC2	3.71e-05	3	123	2	22178260
Pubmed	RANK-c attenuates aggressive properties of ER-negative breast cancer by inhibiting NF-κB activation and EGFR signaling.	TNFRSF11A EGFR	3.71e-05	3	123	2	29844572
Interaction	SIRT7 interactions	USP34 ATXN2L EPPK1 ACLY SMCHD1 INTS1 HNRNPUL1 ANKHD1 TRRAP GTF3C3 SYNE2 YLPM1 ANKRD17 HERC2 EIF3I PHIP SDHA	1.99e-06	744	120	17	int:SIRT7
Interaction	NAA40 interactions	ATXN2L ACLY SMCHD1 ZNF622 PTPN23 HNRNPUL1 ANKHD1 ADAR EMSY NEK1 RBM12 BAZ1A UCHL1 KIAA1217 YLPM1 ANKRD17 EIF3I HERC4 SDCBP	5.08e-06	978	120	19	int:NAA40
Interaction	AR interactions	USP34 EPPK1 WDR33 ACLY SMCHD1 HNRNPUL1 PAK6 TRRAP ADAR EMSY RBM12 SF3B3 MTA3 EGFR KIAA1217 YLPM1 USP12 NR3C2 EIF3I	6.22e-06	992	120	19	int:AR
GeneFamily	ATP binding cassette subfamily C	ABCC3 ABCC12 ABCC2	3.18e-05	13	89	3	807
GeneFamily	Proprotein convertase subtilisin/kexin family	PCSK5 PCSK2	8.43e-04	9	89	2	973
GeneFamily	PDZ domain containing	GOPC PREX2 RAPGEF2 SDCBP PDZD2	9.25e-04	152	89	5	1220
GeneFamily	ATP binding cassette subfamily B	ABCB5 ABCB1	1.28e-03	11	89	2	806
GeneFamily	CD molecules\|Gamma-glutamyltransferases	GGT2P GGT3P	1.80e-03	13	89	2	564
GeneFamily	GATA zinc finger domain containing\|Myb/SANT domain containing	ZSCAN20 MTA3 SNAPC4	2.26e-03	53	89	3	532
GeneFamily	CD molecules\|Integrin alpha subunits	ITGA8 ITGA7	3.48e-03	18	89	2	1160
Coexpression	GSE22611_NOD2_TRANSDUCED_VS_CTRL_HEK293T_STIMULATED_WITH_MDP_2H_DN	ABCB5 MUC16 SF3B3 SYNE2 HEMK1 EIF3I KIF17 PDZD2	2.52e-06	183	123	8	M8178
Coexpression	DACOSTA_UV_RESPONSE_VIA_ERCC3_DN	USP34 HIVEP2 SMCHD1 TRRAP NEK1 EGFR BAZ1A SYNE2 MITF USP12 ANKRD17 BCAR3 RAPGEF2 HERC4 PHIP PHLPP2	2.64e-06	856	123	16	M4500
Coexpression	GSE26669_CTRL_VS_COSTIM_BLOCK_MLR_CD8_TCELL_DN	USP34 MAF1 WDR33 QRICH1 ABCA7 KIAA1217 FAM135A PHLPP2	4.86e-06	200	123	8	M4667
Coexpression	DACOSTA_UV_RESPONSE_VIA_ERCC3_COMMON_DN	HIVEP2 SMCHD1 TRRAP EGFR BAZ1A USP12 ANKRD17 BCAR3 RAPGEF2 PHIP PHLPP2	1.29e-05	466	123	11	M13522
Coexpression	GSE24634_TEFF_VS_TCONV_DAY5_IN_CULTURE_DN	PCSK5 TREX1 HIVEP2 STK17A ABCA7 KIF17 EPHA1	4.42e-05	199	123	7	M4620
Coexpression	GSE22432_UNTREATED_VS_TGFB1_TREATED_COMMON_DC_PROGENITOR_DN	GIMAP4 SIKE1 ABCA7 MTA3 SUOX HERC2 SDHA	4.56e-05	200	123	7	M7828
Coexpression	GSE22886_NAIVE_TCELL_VS_DC_DN	ANPEP NEU1 FCER2 SUOX MITF BCAR3 SDCBP	4.56e-05	200	123	7	M4476
ToppCell	systemic_lupus_erythematosus-flare-Lymphocytic_B-plasmablast\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	PBK MUC16 UCHL1 BTN1A1 BCAR3 SYVN1 CHPF	6.03e-07	176	123	7	dc4e939a07bad21ab36181f9588df3fa662f9a92
ToppCell	COVID-19-Heart-EC_2\|COVID-19 / Disease (COVID-19 only), tissue and cell type	PCSK5 PREX2 KIAA1217 SYNE2 PLCB1 RAPGEF2 PDZD2	6.76e-07	179	123	7	2a53d94f6c30bf887dfe88f1693ea057218c852d
ToppCell	facs-Liver-Hepatocytes-24m-Epithelial\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ANPEP ST3GAL3 GFRA1 CLCN2 EGFR ABCC2 EPHA1	7.55e-07	182	123	7	770ce9f3f4538d0181a0181543841bc964c68274
ToppCell	facs-Liver-Hepatocytes-24m-Epithelial-nan\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ANPEP ST3GAL3 GFRA1 CLCN2 EGFR ABCC2 EPHA1	7.55e-07	182	123	7	77ab860e2add49dad0c1ffbfc64278ad499dfbd5
ToppCell	facs-Liver-Hepatocytes-24m-Epithelial-hepatocyte\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ANPEP ST3GAL3 GFRA1 CLCN2 EGFR ABCC2 EPHA1	7.55e-07	182	123	7	4921c7d5687cc79f896b39753bb621d7e3d2972f
ToppCell	facs-Liver-Hepatocytes-24m\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ABCC3 ANPEP ST3GAL3 GFRA1 CLCN2 EGFR ABCC2	7.84e-07	183	123	7	d0721c6aa426953a520d40e976b6e65aa7ca65e8
ToppCell	frontal_cortex-Neuronal-GABAergic_neuron-Serpinf1-Serpinf1_Clrn1\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	ABCB5 PBK CRTAC1 PCDH20 CDH24 NR3C2	9.47e-07	118	123	6	702548d8187d54e8814375e5ae7609631fc71d5f
ToppCell	Parenchymal-NucSeq-Epithelial-Epi_submucosal-gland-SMG_Serous\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	TNFRSF11A ALG9 PLCB1 CHPF KIF17 CDK3	2.90e-06	143	123	6	92ddc3e3f6ba78dd9daeb272c12503ec2650a874
ToppCell	metastatic_Brain-T/NK_cells-Cytotoxic_CD8+_T\|T/NK_cells / Location, Cell class and cell subclass	PCSK5 ITGA8 MUC16 SCN2B DNAI4 SYVN1	5.75e-06	161	123	6	e6e294b4ba911c1327664f1a0f93207096c6de03
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT2_L6_FEZF2-Exc_L6_FEZF2_KRT17\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	PCSK5 ITGA8 GFRA1 CDH24 KIAA1217 FHIP1A	6.62e-06	165	123	6	fee7f2f8d0e25c0d067adc73f8913721bd709a3e
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT2_L6_FEZF2-Exc_L6_FEZF2_KRT17\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	PCSK5 ITGA8 GFRA1 CDH24 KIAA1217 FHIP1A	6.85e-06	166	123	6	739dfbe927f409821ff23aca6e47ebe78f57e859
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT2_L6_FEZF2\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	PCSK5 ITGA8 GFRA1 CDH24 KIAA1217 FHIP1A	7.09e-06	167	123	6	a6ff7a3d9b80839c0efa91658836812e868561fa
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT2_L6_FEZF2\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	PCSK5 ITGA8 GFRA1 CDH24 KIAA1217 FHIP1A	7.59e-06	169	123	6	0c341f91dc21aaf92bead18d59684d11510502ce
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT2_L6_FEZF2-Exc_L6_FEZF2_KRT17\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	PCSK5 ITGA8 GFRA1 CDH24 KIAA1217 FHIP1A	7.85e-06	170	123	6	84d49a1f2989d98bd0acf9ec2d59f1042fc0f55b
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT2_L6_FEZF2\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	PCSK5 ITGA8 GFRA1 CDH24 KIAA1217 FHIP1A	8.40e-06	172	123	6	cecfe5cf20f317ea01b4604789e07a14481c4cd6
ToppCell	systemic_lupus_erythematosus-flare-Lymphocytic_B-plasmablast-female\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	MUC16 UCHL1 BTN1A1 BCAR3 SYVN1 CHPF	9.27e-06	175	123	6	3b5346fba617292de71963b6175e85a4f182fe30
ToppCell	Posterior_cortex-Neuronal-Inhibitory-iN2(Gad1Gad2)-Cplx3-Inhibitory_Neuron.Gad1Gad2.Cplx3-Reln_(Cortical_subplate_interneuron)\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	RSPH6A FCER2 BTN1A1 ABCC2	1.20e-05	51	123	4	73a6c4354f2f4a7de95d15467b1249f4c57b441e
ToppCell	Posterior_cortex-Neuronal-Inhibitory-iN2(Gad1Gad2)-Cplx3-Inhibitory_Neuron.Gad1Gad2.Cplx3-Reln_(Cortical_subplate_interneuron)-\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	RSPH6A FCER2 BTN1A1 ABCC2	1.20e-05	51	123	4	650d288bd1816b3798025c9fa4cea2f6db639a55
ToppCell	Healthy-MAIT\|Healthy / disease group, cell group and cell class	GIMAP4 TPT1 ABCB1 KIAA1217 SYNE2 PLCB1	1.31e-05	186	123	6	028061f06d86e75cb06db56b199594b80f23fa58
ToppCell	COVID-19-Heart-EC_2\|Heart / Disease (COVID-19 only), tissue and cell type	PCSK5 PREX2 SYNE2 PLCB1 RAPGEF2 FAM135A	1.35e-05	187	123	6	40ffc06a3e3251d9b12da390210d3e045af7537a
ToppCell	Control-Multiplet-Multiplet\|World / Disease state, Lineage and Cell class	CRTAC1 EGFR KIAA1217 SYNE2 NR3C2 FHIP1A	1.57e-05	192	123	6	1bfd022d5b87cf8a5d5069f559339a553a52a0a2
ToppCell	3'-Broncho-tracheal-Endothelial-Blood_vessel_EC-pulmonary_artery_endothelial_cell-EC_arterial-EC_arterial_L.2.4.1.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	PCSK5 GIMAP4 PREX2 ABCB1 CDH24 PLCB1	1.62e-05	193	123	6	3a9fe4e709c09ec787c71bdd6b58a71c419896de
ToppCell	IPF-Stromal-Pericyte\|Stromal / Disease state, Lineage and Cell class	ITGA7 PREX2 SYNE2 PLCB1 RAPGEF2 PDZD2	1.66e-05	194	123	6	3892b188f424ffb80f3c75a1b6709a21c1e1601d
ToppCell	BAL-Severe-Lymphocyte-T/NK-CD8+_T-MAIT\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	GIMAP4 TPT1 ABCB1 SYNE2 PLCB1 EPHA1	1.71e-05	195	123	6	caa3669739974b63470f7e557df96e8d3844dd84
ToppCell	BAL-Severe-Lymphocyte-T/NK-CD8+_T-MAIT-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	GIMAP4 TPT1 ABCB1 SYNE2 PLCB1 EPHA1	1.71e-05	195	123	6	bc5728e9df0b15adec50a7c840ce9f2775135087
ToppCell	Neuron-Postmitotic-Excitatory_Neuron_-IPC/newborn-38\|World / Primary Cells by Cluster	TPT1 BAZ1A SYNE2 PLCB1 PHIP SDCBP	1.76e-05	196	123	6	38da0751941adca650fe9b383d9f343153978eb5
ToppCell	Neuron-Postmitotic-Excitatory_Neuron_-IPC/newborn\|World / Primary Cells by Cluster	TPT1 BAZ1A SYNE2 PLCB1 PHIP SDCBP	1.76e-05	196	123	6	721650a08d260faf530dbd52d4e9275d27f3bac2
ToppCell	healthy_donor-Lymphocytic-T_cell-Gamma_Delta_T_cell\|healthy_donor / Disease condition, Lineage, Cell class and subclass	TPT1 HIVEP2 ABCB1 SYNE2 PLCB1 NR3C2	1.76e-05	196	123	6	6eabbac1625f715531bae562a28da27664572600
ToppCell	mild-Plasmablast\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	TEX14 UCHL1 BTN1A1 HERC2 SYVN1 CHPF	1.81e-05	197	123	6	21085d5e27b5a23a241a933058bb89f8a1fcf198
ToppCell	BL\|World / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	GIMAP4 TAGAP SMCHD1 ADAR BAZ1A SDCBP	1.81e-05	197	123	6	1acf0191fa0a25cd20bfd9ea7bf727a1555986a1
ToppCell	3'_v3-GI_small-bowel-Lymphocytic_T_CD4\|GI_small-bowel / Manually curated celltypes from each tissue	TPT1 HIVEP2 HNRNPUL1 SYNE2 PLCB1 PDZD2	1.87e-05	198	123	6	6333e46cd1ccf5841ce15aea98a4b2f5e3ae4675
ToppCell	CV-Mild-1\|CV / Virus stimulation, Condition and Cluster	GIMAP4 TREX1 SMCHD1 TRIM21 ADAR SYNE2	1.87e-05	198	123	6	4b078714c49e7befb7b113d72485e712236d35fa
ToppCell	mild-Plasmablast\|mild / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	PBK TEX14 UCHL1 BTN1A1 SYVN1 CHPF	1.87e-05	198	123	6	b14b9e67815f93fac7bd8e5e6f1aa100951b4ac1
ToppCell	severe-Plasmablast\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	PBK TEX14 UCHL1 ALG9 SYVN1 CHPF	1.92e-05	199	123	6	6ee4c2e6049860071169366b7e662d5c1a3cc54b
ToppCell	VE-CD4-antiviral_CD4\|VE / Condition, Cell_class and T cell subcluster	GIMAP4 TPT1 SMCHD1 TRIM21 ADAR SYNE2	1.92e-05	199	123	6	056a0538ca5e825ae6195b4c76c208708a014533
ToppCell	Neuronal-Excitatory-eE(FEZF2_SLC17A7)\|Neuronal / cells hierarchy compared to all cells using T-Statistic	PCSK5 ITGA8 GFRA1 CDH24 KIAA1217 FHIP1A	1.97e-05	200	123	6	501cd2b4e55444fc5fdd93ebbcfc0616442b110b
ToppCell	LPS_IL1RA-Endothelial-Endothelial-Gen_Cap\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	GIMAP4 USP34 PREX2 KIAA1217 SYNE2 FAM135A	1.97e-05	200	123	6	dccec522ab0d7fff62ad6273b02aa9022dbbb8eb
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW10\|organoid_Tanaka_cellReport / Sample Type, Dataset, Time_group, and Cell type.	BOC PCSK2 ACLY PBK SYNE2 PHIP	1.97e-05	200	123	6	7c495030e6566b81d97b5516d1972e335ce5ed8c
ToppCell	Neuronal-Excitatory-eE(FEZF2_SLC17A7)-eE_2-SLC17A7_IL15-\|Neuronal / cells hierarchy compared to all cells using T-Statistic	PCSK5 ITGA8 CDH24 KIAA1217 MITF FHIP1A	1.97e-05	200	123	6	48fd48990a6833066be314dc5b66b90893f7ea8f
ToppCell	LPS_IL1RA_TNF-Endothelial-Endothelial-Artery\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	PCSK5 GIMAP4 PREX2 SYNE2 PLCB1 FAM135A	1.97e-05	200	123	6	77ae679c35d3b9e2b620f34129f3a8d47e922c65
ToppCell	Control_saline-Endothelial-Endothelial-Artery\|Control_saline / Treatment groups by lineage, cell group, cell type	PCSK5 GIMAP4 PREX2 SYNE2 PLCB1 FAM135A	1.97e-05	200	123	6	65b71f1e8da5c3750fcd0a2e66d9ef3125a3f78a
ToppCell	Neuronal-Excitatory-eE(FEZF2_SLC17A7)-eE_1(EFTUD1P1)---L5-6\|Neuronal / cells hierarchy compared to all cells using T-Statistic	PCSK5 ITGA8 GFRA1 CDH24 KIAA1217 FHIP1A	1.97e-05	200	123	6	046a3a4d7e4d84ee4252a695ffd4a6aee8b77070
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	ABCC3 ANPEP ACLY ABCB1 NEU1 SYNE2	1.97e-05	200	123	6	105564ee05bd11685b5747ee32d5350cf3c2e2e1
ToppCell	Neuronal-Excitatory-eE(FEZF2_SLC17A7)-eE_1(EFTUD1P1)-\|Neuronal / cells hierarchy compared to all cells using T-Statistic	PCSK5 ITGA8 GFRA1 CDH24 KIAA1217 FHIP1A	1.97e-05	200	123	6	893cc7f6b9794da90aa0c9d721b8647dc97201cd
ToppCell	Neuronal-Excitatory-eE(FEZF2_SLC17A7)-eE_1(EFTUD1P1)\|Neuronal / cells hierarchy compared to all cells using T-Statistic	PCSK5 ITGA8 GFRA1 CDH24 KIAA1217 FHIP1A	1.97e-05	200	123	6	3d677f13e429abc805a52ec2b8f36c703f511569
ToppCell	Neuronal-Excitatory-eE(FEZF2_SLC17A7)-eE_2-SLC17A7_IL15--L5-6\|Neuronal / cells hierarchy compared to all cells using T-Statistic	PCSK5 ITGA8 CDH24 KIAA1217 MITF FHIP1A	1.97e-05	200	123	6	9103e6f72a04f66f2b7069b0d71a719e9b10026b
ToppCell	LPS_only-Endothelial-Endothelial-Artery\|LPS_only / Treatment groups by lineage, cell group, cell type	PCSK5 GIMAP4 PREX2 SYNE2 PLCB1 FAM135A	1.97e-05	200	123	6	b17eb1587ca86c3d40515128a00a8d8fd787fccf
ToppCell	Neuronal-Excitatory-eE(FEZF2_SLC17A7)-eE_1(EFTUD1P1)--\|Neuronal / cells hierarchy compared to all cells using T-Statistic	PCSK5 ITGA8 GFRA1 CDH24 KIAA1217 FHIP1A	1.97e-05	200	123	6	12518f4a8d01fc66b72878cdf0ba124b37cff3d8
ToppCell	LPS_anti-TNF-Endothelial-Endothelial-Artery\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	PCSK5 GIMAP4 PREX2 SYNE2 PLCB1 FAM135A	1.97e-05	200	123	6	b1ff8d61b567f85006d6d20093f9c803b6d34674
ToppCell	Neuronal-Excitatory-eE(FEZF2_SLC17A7)-eE_2-SLC17A7_IL15\|Neuronal / cells hierarchy compared to all cells using T-Statistic	PCSK5 ITGA8 CDH24 KIAA1217 MITF FHIP1A	1.97e-05	200	123	6	e5e97767beb4413e87c9817a60a5f1ee5209198a
ToppCell	facs-Trachea-3m-Mesenchymal-fibroblast-fibroblast_of_trachea-\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	RSPH6A TEX14 CDH24 FCER2 SCN5A	2.95e-05	129	123	5	cbeeaa554da971ba2e4c4b82c85a1d070a45abb8
ToppCell	PBMC-Mild-cDC_2\|Mild / Compartment, Disease Groups and Clusters	TREX1 EPPK1 SYNE2 PHLPP2 PDZD2	3.67e-05	135	123	5	cb9d834f8301cf53f20e09c3f4cb6a148690196a
ToppCell	frontal_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Lmo1_Myl1\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	PCDH20 EGFR BTN1A1 SCN5A NR3C2	5.16e-05	145	123	5	590ba937c741ae67460f303eca88b1cd3ac87f64
ToppCell	droplet-Marrow-nan-21m-Hematologic-erythroid_progenitor\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GIMAP4 ZSCAN20 BCAR3 FHIP1A PLEKHA8	8.73e-05	162	123	5	d0ffebf5adee8a3ac9b81a4b793184f54010489a
ToppCell	Striatum-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Th-Inhibitory_Neuron.Gad1Gad2-Th.Trh_(Th+_interneuron)\|Striatum / BrainAtlas - Mouse McCarroll V32	C11orf42 BTN1A1 TPH2 EPHA1	9.08e-05	85	123	4	67336aa7ec02b64595ce7d5222d43cead92eb52e
ToppCell	Striatum-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Th\|Striatum / BrainAtlas - Mouse McCarroll V32	C11orf42 BTN1A1 TPH2 EPHA1	9.08e-05	85	123	4	a7a5d82924cd4a41ab87b1abf13143635882a4b2
ToppCell	Striatum-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Th-Inhibitory_Neuron.Gad1Gad2-Th.Trh_(Th+_interneuron)-\|Striatum / BrainAtlas - Mouse McCarroll V32	C11orf42 BTN1A1 TPH2 EPHA1	9.08e-05	85	123	4	86c5d71b66ff55c44d2d457865dda72e07e5ec53
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT2_L6_FEZF2-Exc_L6_FEZF2_TBCC\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	PCSK5 TRIM21 ABCB1 CDH24 FHIP1A	9.52e-05	165	123	5	7978eefcfc40175e933f7a8b64a5dd1c661dd1ac
ToppCell	Somatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT2_L6_FEZF2\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	PCSK5 ITGA8 CDH24 KIAA1217 FHIP1A	1.04e-04	168	123	5	217770a94ace446cdfc7687b459dece707576e76
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT2_L6_FEZF2-Exc_L6_FEZF2_SLITRK6\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	PCSK5 CDH24 KIAA1217 MITF FHIP1A	1.06e-04	169	123	5	1c9e54e7b14eb99996590fb93b257cf881a9f184
ToppCell	BAL-Control-Lymphocyte-T/NK-NK_cell-NK-\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	HIVEP2 TNFRSF11A ABCB1 SYNE2 PLCB1	1.06e-04	169	123	5	e9c0e0f4c421c7bdbf1a7e33002f3cf22ea307cb
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT2_L6_FEZF2-Exc_L6_FEZF2_ETV4\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	PCSK5 ITGA8 CDH24 KIAA1217 FHIP1A	1.06e-04	169	123	5	716e9d4c5fb99c56b76afaa5ed90bfa859fde802
ToppCell	3'-GW_trimst-2-LargeIntestine-Neuronal-Glial_immature-Glia_3_(BCAN+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	PCDH20 GFRA1 UCHL1 SCN5A BCAR3	1.06e-04	169	123	5	2456b3e7776e8a2214972be1b4d66a3ca5480ae0
ToppCell	BAL-Control-Lymphocyte-T/NK-NK_cell\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	HIVEP2 TNFRSF11A ABCB1 SYNE2 PLCB1	1.06e-04	169	123	5	d375a1df1ecc938f66bad92e54b8cda26ca9c472
ToppCell	BAL-Control-Lymphocyte-T/NK-NK_cell-NK\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	HIVEP2 TNFRSF11A ABCB1 SYNE2 PLCB1	1.06e-04	169	123	5	58f805c0be507bd5fadc9ea3555032daabbc8ab8
ToppCell	ileum\|World / shred on tissue and cell subclass	ANPEP ABCB1 CLCN2 ABCC2 PHLPP2	1.09e-04	170	123	5	9f1211bd4287620e19a59f21e6ecdca3e42e0260
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	PCSK5 ITGA8 ABCB1 CDH24 KIAA1217	1.09e-04	170	123	5	417b77c12a7982b1ce4b4bc57f30335d261220f5
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT2_L6_FEZF2-Exc_L6_FEZF2_TBCC\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	PCSK5 ABCB1 CDH24 KIAA1217 FHIP1A	1.22e-04	174	123	5	912a9e892b29d945666fc37c986009c97c668ac8
ToppCell	3'-Broncho-tracheal-Endothelial-Blood_vessel_EC-pulmonary_artery_endothelial_cell-EC_arterial-EC_arterial_L.2.4.0.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	PCSK5 GIMAP4 ABCB1 PLCB1 CDK3	1.22e-04	174	123	5	18ab52d8bbca0507fee220e0c4fc765fc47dda34
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	PCSK5 ABCB1 CDH24 KIAA1217 FHIP1A	1.22e-04	174	123	5	e4d65fe121a32ac4cdd6312e7b8f867f0852e991
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT2_L6_FEZF2\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	PCSK5 ITGA8 CDH24 KIAA1217 FHIP1A	1.22e-04	174	123	5	7d4b860e05b5931f6f9d757a68f75ff35597a47a
ToppCell	facs-Marrow-B-cells-24m-Lymphocytic-naive_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PCSK2 GIMAP4 TPT1 FCER2 BCAR3	1.25e-04	175	123	5	82482f3fc716701bed46dc65c2044577aed15427
ToppCell	facs-Marrow-B-cells-24m-Lymphocytic-naive_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PCSK2 GIMAP4 TPT1 FCER2 BCAR3	1.25e-04	175	123	5	5092c5159f697e20bf8aa450c414ffd997738d25
ToppCell	facs-Marrow-KLS-18m-Lymphocytic-early_pro_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PCSK5 ZBTB41 GFRA1 UCHL1 KIF17	1.29e-04	176	123	5	7292e014b8f697f0c2e9f47c48333de95cb44a69
ToppCell	facs-Large_Intestine-Proximal-3m-Epithelial-enterocyte_of_epithelium_of_large_intestine\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PCSK5 ABCC3 NEU1 CLCN2 PLEKHA8	1.29e-04	176	123	5	7622f5a8e7320cc7b593141854107ecaf4adff7f
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_E_(THEMIS)-Glut_IT_L5/L6_Car3_THEMIS-Exc_L5-6_THEMIS_GPR21\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	PCSK5 ABCC3 CRTAC1 ITGA7 GFRA1	1.29e-04	176	123	5	ed7ba2a3af3b060dec98b60f09f96000a67f7e63
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_3\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	ABCC3 ANPEP SYNE2 ABCC2 PDZD2	1.29e-04	176	123	5	1595dbeee336a81e581325d63208ec6262664ee9
ToppCell	facs-Marrow-KLS-18m-Lymphocytic-early_pro-B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PCSK5 ZBTB41 GFRA1 UCHL1 KIF17	1.29e-04	176	123	5	88ca2f83d8301633232735f39b0683efe49d0b86
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_3\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ABCC3 ANPEP SYNE2 ABCC2 PDZD2	1.32e-04	177	123	5	2f81b26be89cc2fd8eafadaf7eae3c6ad6521462
ToppCell	Healthy_donor-Plasmablast\|Healthy_donor / disease group, cell group and cell class (v2)	BOC PBK UCHL1 BTN1A1 CHPF	1.36e-04	178	123	5	388b8b4fa20dcc6e9ae4b06118e20b2c20c52bde
ToppCell	LPS_only-Epithelial_alveolar-AT_2-Differentiating_AT2\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	BOC TEX14 EGFR SYNE2 FHIP1A	1.39e-04	179	123	5	fd2cbee532e7b44113410dca82aec7db1a7fb69f
ToppCell	COVID-19-kidney-PLVAP+EC\|COVID-19 / Disease (COVID-19 only), tissue and cell type	BOC ITGA8 KIAA1217 SYNE2 PLCB1	1.43e-04	180	123	5	493cf8d1a8f2a1ed2672f394a0338b110fd81d88
ToppCell	10x5'-Liver-Lymphocytic_T_CD4-T_CD4/CD8\|Liver / Manually curated celltypes from each tissue	USP34 SMCHD1 SYNE2 PLCB1 HERC4	1.47e-04	181	123	5	f2315414e714ac86211546a935660c4be6e85f1b
ToppCell	367C-Fibroblasts-Fibroblast-G-\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	PCSK2 ABCC3 PAK6 EPHA1	1.51e-04	97	123	4	a1279377bf0ee5662db8b9303f5f1fd418dee6df
ToppCell	367C-Fibroblasts-Fibroblast-G\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	PCSK2 ABCC3 PAK6 EPHA1	1.51e-04	97	123	4	12cbd03b33e76e5e471bbee2a9c11f27e8b21123
ToppCell	Control-Epithelial_cells-Airway_mucous\|Control / group, cell type (main and fine annotations)	ABCC3 MUC16 FER1L6 ANXA10 PLCB1	1.54e-04	183	123	5	15d24a4fb1ffe6cbafbd54fcd7dde9ddcfbe03b2
ToppCell	Calu_3-infected\|Calu_3 / Cell line, Condition and Strain	SMCHD1 TRIM21 ADAR BAZ1A SYNE2	1.54e-04	183	123	5	8f7f5000645f24f20a8d7700c4df1f8953a1780b
ToppCell	3'_v3-lymph-node_spleen-Lymphocytic_Invariant-Inducer-like\|lymph-node_spleen / Manually curated celltypes from each tissue	ABCB5 PCDH20 ABCB1 KIAA1217 PLCB1	1.58e-04	184	123	5	d97471a4fe17cba6880ccf1a04cc00c741558124
ToppCell	BAL-Control-Myeloid-MoAM-MoAM4\|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)	BOC ANPEP SH3PXD2B FCER2 UCHL1	1.63e-04	185	123	5	274b8acccdfe434d14af4cb32fb615c06ec98435
ToppCell	BAL-Control-Myeloid-MoAM-MoAM4-\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	BOC ANPEP SH3PXD2B FCER2 UCHL1	1.63e-04	185	123	5	b640d9ed6a1e6aa595053065bb992efc0402353e
ToppCell	10x_5'_v1-Non-neoplastic-Myeloid-Mono-Mono_anti-infl-Z\|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	ABCC3 ANPEP TNFRSF11A SH3PXD2B ABCC2	1.67e-04	186	123	5	f73cb91e74a806858650ae97f543fc779ba4cff8
ToppCell	10x_5'_v1-Non-neoplastic-Myeloid-Mono-Mono_anti-infl\|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	ABCC3 ANPEP TNFRSF11A SH3PXD2B ABCC2	1.67e-04	186	123	5	8694ca16c9780729f4fba67ba20e35745f1eb4e9
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_3\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	ABCC3 ANPEP SYNE2 ABCC2 PDZD2	1.67e-04	186	123	5	b1edc341d6684b347dc9e21b34f62f51d095d735
ToppCell	Fetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2-D062\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	CRTAC1 GGT2P NR3C2 FHIP1A PDZD2	1.71e-04	187	123	5	5df9e1f5ca32217af255e76e6fb5afa346337811
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PCSK5 ANPEP SYNE2 ABCC2 PDZD2	1.71e-04	187	123	5	dcf6475ece5b34d9d58a0d1f51c18acedb19c119
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PCSK5 ANPEP SYNE2 ABCC2 PDZD2	1.71e-04	187	123	5	f1356273bd3587b6883295edf15cb9cdb706c057
ToppCell	COVID-19-kidney-Stressed_PCT\|kidney / Disease (COVID-19 only), tissue and cell type	PCSK5 ANPEP ABCB1 ABCC2 PDZD2	1.71e-04	187	123	5	acd305475f3609800af0d7bc68d83ef41228080b
ToppCell	10x5'-GI_small-bowel-Lymphocytic_T_CD4-T_CD4/CD8\|GI_small-bowel / Manually curated celltypes from each tissue	USP34 SMCHD1 SYNE2 PLCB1 RAPGEF2	1.75e-04	188	123	5	ab9b725d6e0cdab8e9ddda6dee09e14730e9a578
ToppCell	T_cells-ISG-high_CD4+_T_cells\|World / Immune cells in Kidney/Urine in Lupus Nephritis	GIMAP4 SMCHD1 TRIM21 ADAR SYNE2	1.75e-04	188	123	5	6f8946d4710f6e32c937213f99b790b098b8819c
ToppCell	wk_08-11-Epithelial-PNS-MFNG+_DBH+_neuron\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	PCSK2 GFRA1 ABCB1 UCHL1 SCN5A	1.75e-04	188	123	5	d3d7d21d4fa39ac4106a164652673de1bef8662d
Drug	nicotine glucuronide	ABCC3 ABCB5 ABCB1 ABCC2	5.58e-08	8	123	4	CID003035848
Drug	lovastatin acid	ABCC3 ABCB5 ABCB1 SYNE2 ABCC2	6.16e-08	20	123	5	CID000064727
Drug	Texas Red	ABCC3 ABCB5 ABCB1 NR3C2 ABCC2	3.77e-07	28	123	5	CID000452705
Drug	5-carboxyfluorescein diacetate	ABCC3 ABCB5 ABCB1 ABCC2	5.58e-07	13	123	4	CID000133314
Drug	macitentan	ABCC3 ABCB1 ABCC2	6.13e-07	4	123	3	ctd:C533860
Drug	robinetin	ABCB5 ABCB1 ABCC2 PHIP	7.79e-07	14	123	4	CID005281692
Drug	tetramethylrosamine	ABCC3 ABCB5 ABCB1 ABCC2	7.79e-07	14	123	4	CID000443313
Drug	PAK-104P	ABCC3 ABCB5 ABCB1 ABCC2	1.06e-06	15	123	4	CID000131368
Drug	AC1L4BIC	ABCC3 ABCB5 ABCB1 ABCC2	1.40e-06	16	123	4	CID000153998
Drug	Taxane	ABCC3 ABCB5 ABCB1 EGFR ABCC12 ABCC2 PDZD2	1.46e-06	103	123	7	CID000108169
Drug	mitoxantrone	PCSK5 ABCC3 ANPEP ABCB5 ABCA7 ABCB1 ABCC2 PDZD2	1.95e-06	154	123	8	CID000004212
Drug	Apa-sg	ABCC3 ABCB5 ABCB1 ABCC2	2.95e-06	19	123	4	CID000126348
Drug	NSC695241	ABCC3 ABCB5 ABCB1	3.04e-06	6	123	3	CID000003584
Drug	v 104	ABCB5 ABCB1 ABCC2	3.04e-06	6	123	3	CID000107262
Drug	O746	ABCC3 ABCB5 ABCB1 ABCC2	3.67e-06	20	123	4	CID006327063
Drug	atazanavir	BOC ABCC3 ACLY ABCB5 ABCB1 ABCC2 SDHA	4.06e-06	120	123	7	CID000148192
Drug	AC1Q5X3R	ABCC3 ABCB5 ABCB1 ABCC2	5.50e-06	22	123	4	CID000108075
Drug	VX-710	ABCC3 ABCB5 ABCB1 ABCC2	5.50e-06	22	123	4	CID000406509
Drug	estradiol-17 beta-glucuronide	ABCC3 ABCB1 EGFR ABCC2	5.50e-06	22	123	4	ctd:C025483
Drug	hydroxyrubicin	ABCC3 ABCB5 ABCB1 ABCC2	6.63e-06	23	123	4	CID000072398
Drug	calcein AM	ABCC3 ABCB1 ABCC2	8.45e-06	8	123	3	ctd:C085925
Drug	T beta-MC	ABCC3 ABCB1 ABCC2	8.45e-06	8	123	3	CID000168408
Drug	3-isoreserpine	ABCC3 ABCB5 ABCA7 ABCB1 SF3B3 TPH2 ABCC12 ABCC2	9.22e-06	190	123	8	CID000005052
Drug	AC1NE3ZR	PCSK5 ABCC3 ABCB1 ABCC2	1.11e-05	26	123	4	CID004636208
Drug	(+,-)-Synephrine [94-07-5]; Down 200; 24uM; MCF7; HT_HG-U133A	SIKE1 ZNF768 EMSY NEK1 MITF PLCB1 HERC4 EPHA1	1.16e-05	196	123	8	6798_DN
Drug	N-Acetyl-DL-homocysteine Thiolactone [1195-16-0]; Down 200; 25.2uM; MCF7; HT_HG-U133A	CACNA1A ABCC3 ITGA8 EMSY HEMK1 ABCC2 SNAPC4 CDK3	1.20e-05	197	123	8	3930_DN
Drug	(R) -Naproxen sodium salt [26159-34-2]; Down 200; 15.8uM; PC3; HT_HG-U133A	ABCC3 SIKE1 TRRAP EGFR ANXA10 NR3C2 HERC4 PDZD2	1.20e-05	197	123	8	7146_DN
Drug	IAARh123	ABCB5 ABCB1 ABCC2	1.26e-05	9	123	3	CID000656577
Drug	So324	ANPEP ABCB5 ABCB1	1.26e-05	9	123	3	CID000462261
Drug	N-methylmorpholine	BOC ACLY ABCB5 ABCB1 BTN1A1 NR3C2	1.45e-05	97	123	6	CID000007972
Drug	3 alpha,6 alpha-dihydroxy-5 beta-cholanoic acid	ABCC3 ABCB5 ABCB1 ABCC2	1.74e-05	29	123	4	CID000006747
Drug	6-methylpurine-2'-deoxyriboside	ABCC3 ABCB5 ABCB1 NR3C2 ABCC2	1.98e-05	61	123	5	CID000097184
Drug	AC1L9E0Q	ABCC3 ABCB5 ABCB1 ABCC2	1.99e-05	30	123	4	CID000443095
Drug	17beta-estradiol glucuronide	ABCC3 ABCB5 ABCB1 ABCC2	2.59e-05	32	123	4	CID000066424
Drug	AC1LCF1F	ABCC3 ABCB5 ABCB1 RBM12 ABCC12 ABCC2 PHIP	2.77e-05	161	123	7	CID000627275
Drug	enkephalin-Leu, Ala(2)-melphalan methyl ester-	ABCB1 ABCC2	2.89e-05	2	123	2	ctd:C040240
Drug	mesochlorin e6 monoethylenediamine	ABCB5 ABCB1	2.89e-05	2	123	2	CID005488855
Drug	5(6)-carboxy-2',7'-dichlorofluorescein	ABCC3 ABCC2	2.89e-05	2	123	2	ctd:C053897
Drug	taxuspine C	ABCB5 ABCB1	2.89e-05	2	123	2	CID005321745
Drug	2,2-diphenyl-1,3-dioxolane	ABCB5 ABCB1	2.89e-05	2	123	2	CID000283230
Drug	Ro44-5912	ABCB5 ABCB1	2.89e-05	2	123	2	CID000197370
Drug	8-(3,3-dimethylallyl)chrysin	ABCB5 ABCB1	2.89e-05	2	123	2	CID005281903
Drug	AC1L8LCS	ABCB5 ABCB1	2.89e-05	2	123	2	CID000383419
Drug	sulfurmycin A	ABCB5 ABCB1	2.89e-05	2	123	2	CID000155836
Drug	DAPDOX	ABCB5 ABCB1	2.89e-05	2	123	2	CID000164413
Drug	AC1Q6JJG	ABCB5 ABCB1	2.89e-05	2	123	2	CID000164322
Drug	YM212	ABCB5 ABCB1	2.89e-05	2	123	2	CID000129980
Drug	Ro11-2933	ABCB5 ABCB1	2.89e-05	2	123	2	CID000115215
Drug	cnidiadin	ABCB5 ABCB1	2.89e-05	2	123	2	CID005315980
Drug	conferone	ABCB5 ABCB1	2.89e-05	2	123	2	CID001757335
Drug	benzoylmesaconine	ABCB1 ABCC2	2.89e-05	2	123	2	ctd:C085283
Drug	VX-710-3	ABCB5 ABCB1	2.89e-05	2	123	2	CID006450549
Drug	NAc-LLY-amide	ABCB5 ABCB1	2.89e-05	2	123	2	CID000443109
Drug	benzoylaconine	ABCB1 ABCC2	2.89e-05	2	123	2	ctd:C047307
Drug	E3040 glucuronide	ABCC3 ABCC2	2.89e-05	2	123	2	CID000443294
Drug	62820-12-6	ABCB5 ABCB1	2.89e-05	2	123	2	CID006449905
Drug	AC1L85AO	ABCC3 ABCB5 ABCB1 NR3C2 ABCC2	2.91e-05	66	123	5	CID000372705
Drug	Bt-m	BOC CACNA1A TNFRSF11A BTN1A1	2.94e-05	33	123	4	CID000005963
Drug	diflomotecan	ABCB5 ABCB1 EGFR ABCC2	2.94e-05	33	123	4	CID000219023
Drug	AC1L8YYB	ABCC3 ABCB5 ABCB1 ABCC2	3.32e-05	34	123	4	CID000435167
Drug	SB-C	PCSK5 ABCB5 ABCB1 EGFR CHPF	3.61e-05	69	123	5	CID005331010
Drug	harmol sulfate	ABCC3 ABCB1 ABCC2	4.23e-05	13	123	3	CID005488302
Drug	TpTpT	TPT1 ABCB5 TNFRSF11A ABCB1 SCN5A	4.44e-05	72	123	5	CID006441083
Drug	AC1L1TSE	ABCC3 ABCB5 ABCA7 ABCB1 ABCC2	4.44e-05	72	123	5	CID000060719
Drug	benzbromarone	ABCC3 ABCB5 ABCB1 ABCC2	4.67e-05	37	123	4	CID000002333
Drug	PhIP-HCl	ABCC3 ABCB5 ABCB1 ABCC2 PHIP PDZD2	5.58e-05	123	123	6	CID000001530
Drug	LTC4 (leukotriene C4	BOC ABCC3 ABCB5 ABCB1 FCER2 ABCC12 ABCC2	5.64e-05	180	123	7	CID000003907
Drug	CMFDA	ABCC3 ABCB5 ABCB1 ABCC2	6.38e-05	40	123	4	CID000122297
Drug	AC1O52TI	ABCB5 ABCB1 NR3C2	6.68e-05	15	123	3	CID006426890
Drug	AC1Q6X9N	ABCC3 ABCB5 ABCB1 ABCC2	7.74e-05	42	123	4	CID000072205
Drug	LY 294002; Up 200; 10uM; MCF7; HT_HG-U133A	HIVEP2 CHRNG YLPM1 PLCB1 HEMK1 SNAPC4 CDK3	7.93e-05	190	123	7	6956_UP
Drug	LY 294002; Down 200; 10uM; HL60; HT_HG-U133A	ATXN2L TPT1 ZNF768 EMSY SUOX RIPOR1 CDK3	8.47e-05	192	123	7	2699_DN
Drug	2-chloroquinazoline	ABCB5 ABCB1	8.65e-05	3	123	2	CID000074054
Drug	fluoroanilinoazatoxin	ABCB5 ABCB1	8.65e-05	3	123	2	CID000378896
Drug	NSC123895	BOC ABCB1	8.65e-05	3	123	2	CID000413765
Drug	Dihydrocyclosporin C	ABCB5 ABCB1	8.65e-05	3	123	2	CID000196411
Drug	NSC82591	ABCB5 ABCB1	8.65e-05	3	123	2	CID000579054
Drug	CID5317124	ABCB5 ABCB1	8.65e-05	3	123	2	CID005317124
Drug	NSC688503	ABCB5 ABCB1	8.65e-05	3	123	2	CID000390744
Drug	Cp-100356	ABCB5 ABCB1	8.65e-05	3	123	2	CID000196918
Drug	BIBW22BS	ABCB5 ABCB1	8.65e-05	3	123	2	CID000132088
Drug	AC1NSGRQ	ABCB5 ABCB1	8.65e-05	3	123	2	CID005333904
Drug	prulifloxacin	ABCB1 ABCC2	8.65e-05	3	123	2	ctd:C074191
Drug	taxinine	ABCB5 ABCB1	8.65e-05	3	123	2	CID005321702
Drug	Hapalosin	ABCB5 ABCB1	8.65e-05	3	123	2	CID000133055
Drug	haemanthidine	ABCB5 ABCB1	8.65e-05	3	123	2	CID000124066
Drug	taccalonolide A	ABCB5 ABCB1	8.65e-05	3	123	2	CID000441685
Drug	taccalonolide E	ABCB5 ABCB1	8.65e-05	3	123	2	CID005321583
Drug	iodomycin	ABCB5 ABCB1	8.65e-05	3	123	2	CID000149155
Drug	isopropyl 5,12-hydroxypentadeca-8,10-dien-6,14-diynoate	ABCB1 ABCC2	8.65e-05	3	123	2	ctd:C000603302
Drug	R101933	ABCB5 ABCB1	8.65e-05	3	123	2	CID000219080
Drug	methylazatoxin	ABCB5 ABCB1	8.65e-05	3	123	2	CID000148162
Drug	dendroamide A	ABCB5 ABCB1	8.65e-05	3	123	2	CID000177307
Drug	benzoylhypaconine	ABCB1 ABCC2	8.65e-05	3	123	2	ctd:C479202
Drug	Wp159	ABCB5 ABCB1	8.65e-05	3	123	2	CID003060549
Drug	AC1L2Z11	ABCB5 ABCB1	8.65e-05	3	123	2	CID000080228
Drug	NK-250	ABCB5 ABCB1	8.65e-05	3	123	2	CID000164220
Drug	5-N-acetylardeemin	ABCB5 ABCB1	8.65e-05	3	123	2	CID000127303
Drug	1-bromo-4-chlorobutane	ABCB5 ABCB1	8.65e-05	3	123	2	CID000081364
Drug	mesaconitine	ABCB1 ABCC2	8.65e-05	3	123	2	ctd:C019470
Disease	cystic fibrosis (implicated_via_orthology)	ABCB5 ABCB1 CLCN2 ABCC12	3.34e-08	9	121	4	DOID:1485 (implicated_via_orthology)
Disease	Colorectal Carcinoma	BOC PCSK2 ABCC3 ABCB5 PAK6 PREX2 ABCB1 EGFR NR3C2 ABCC2 PHIP EPHA1	3.30e-05	702	121	12	C0009402
Disease	Cardiomyopathy, Dilated	EGFR SCN5A NR3C2 SDHA	4.55e-05	48	121	4	C0007193
Disease	Aicardi-Goutieres syndrome (implicated_via_orthology)	TREX1 ADAR	9.95e-05	4	121	2	DOID:0050629 (implicated_via_orthology)
Disease	renal agenesis (is_implicated_in)	ITGA8 GFRA1	9.95e-05	4	121	2	DOID:14766 (is_implicated_in)
Disease	Colorectal Neoplasms	BOC ABCC3 ABCB5 ABCB1 EGFR ABCC2 EPHA1	1.51e-04	277	121	7	C0009404
Disease	Bone Diseases, Developmental	PCSK5 CHRNG SH3PXD2B	1.83e-04	27	121	3	C0005941
Disease	Aicardi-Goutieres Syndrome 2	TREX1 ADAR	2.47e-04	6	121	2	C3489724
Disease	Congenital muscular dystrophy (disorder)	ITGA7 SYNE2	2.47e-04	6	121	2	C0699743
Disease	Aicardi Goutieres syndrome	TREX1 ADAR	2.47e-04	6	121	2	cv:C0393591
Disease	AICARDI-GOUTIERES SYNDROME 1	TREX1 ADAR	2.47e-04	6	121	2	C0796126
Disease	fatty liver disease (biomarker_via_orthology)	ABCC3 SUOX ABCC2	3.35e-04	33	121	3	DOID:9452 (biomarker_via_orthology)
Disease	Pseudo-TORCH syndrome	TREX1 ADAR	3.46e-04	7	121	2	C3489725
Disease	aflatoxins-related hepatocellular carcinoma (biomarker_via_orthology)	GGT2P GGT3P	3.46e-04	7	121	2	DOID:5022 (biomarker_via_orthology)
Disease	bilirubin metabolic disorder (biomarker_via_orthology)	ABCC3 ABCC2	3.46e-04	7	121	2	DOID:2741 (biomarker_via_orthology)
Disease	Dystonia	CACNA1A TREX1 ADAR SUOX	4.41e-04	86	121	4	C0013421
Disease	Ventricular Septal Defects	PCSK5 SALL4	4.59e-04	8	121	2	C0018818
Disease	alcohol dependence (biomarker_via_orthology)	GGT2P GGT3P	4.59e-04	8	121	2	DOID:0050741 (biomarker_via_orthology)
Disease	AICARDI-GOUTIERES SYNDROME	TREX1 ADAR	4.59e-04	8	121	2	C0393591
Disease	Attached earlobe	HIVEP2 KIAA1217	4.59e-04	8	121	2	HP_0009907
Disease	Major Depressive Disorder	ANPEP ABCB1 EGFR TPH2 PLCB1 NR3C2	5.12e-04	243	121	6	C1269683
Disease	Intellectual Disability	TREX1 HIVEP2 PTPN23 QRICH1 ST3GAL3 TRRAP GTF3C3 PHIP	5.28e-04	447	121	8	C3714756
Disease	eosinophilic esophagitis	PCSK2 EMSY NEK1 NEU1 KIF17	5.74e-04	163	121	5	EFO_0004232
Disease	leukodystrophy (implicated_via_orthology)	CLCN2 SDHA	5.89e-04	9	121	2	DOID:10579 (implicated_via_orthology)
Disease	Aicardi-Goutieres syndrome (is_implicated_in)	TREX1 ADAR	5.89e-04	9	121	2	DOID:0050629 (is_implicated_in)
Disease	sphingolipid measurement	ABCA7 NEU1 SYNE2	5.95e-04	40	121	3	EFO_0004622
Disease	Unipolar Depression	ANPEP ABCB1 EGFR TPH2 PLCB1 NR3C2	7.15e-04	259	121	6	C0041696
Disease	age at onset, multiple sclerosis	PCSK5 AXDND1	7.35e-04	10	121	2	EFO_0004847, MONDO_0005301
Disease	gallbladder neoplasm	EGFR UCHL1	8.95e-04	11	121	2	C0016978
Disease	Malignant neoplasm of gallbladder	EGFR UCHL1	8.95e-04	11	121	2	C0153452
Disease	cholestasis (biomarker_via_orthology)	ABCC3 ABCB1 ABCC2	1.08e-03	49	121	3	DOID:13580 (biomarker_via_orthology)
Disease	Cardiomyopathy, Familial Idiopathic	EGFR NR3C2 SDHA	1.15e-03	50	121	3	C1449563
Disease	glycochenodeoxycholate glucuronide (1) measurement	ABCC3 ABCC2	1.26e-03	13	121	2	EFO_0800474
Disease	X-24588 measurement	ABCC3 ABCC2	1.26e-03	13	121	2	EFO_0800898
Disease	Brugada Syndrome 1	SCN2B SCN5A	1.26e-03	13	121	2	C4551804
Disease	Squamous cell carcinoma of the head and neck	ABCB1 EGFR ABCC2	1.28e-03	52	121	3	C1168401
Disease	Uveal Melanoma	DEPDC4 GFRA1 HERC2	1.36e-03	53	121	3	EFO_1000616
Disease	familial atrial fibrillation (is_implicated_in)	SCN2B SCN5A	1.47e-03	14	121	2	DOID:0050650 (is_implicated_in)
Disease	Malignant neoplasm of breast	BOC ADAR PCDH20 EMSY ABCB1 LLGL1 EGFR SYNE2 PLCB1 BCAR3 HERC2 PLEKHA8	1.56e-03	1074	121	12	C0006142
Disease	amyotrophic lateral sclerosis, age at onset	PCSK5 ST3GAL3	1.69e-03	15	121	2	EFO_0004847, MONDO_0004976
Disease	X-21441 measurement	ABCC3 ABCC2	2.18e-03	17	121	2	EFO_0800814
Disease	sphingomyelin 14:0 measurement	PAK6 SYNE2	2.18e-03	17	121	2	EFO_0010390
Disease	carcinoma (implicated_via_orthology)	SALL4 LLGL1 EGFR	2.34e-03	64	121	3	DOID:305 (implicated_via_orthology)
Disease	Adrenocortical carcinoma	ABCB1 EGFR	2.44e-03	18	121	2	C0206686
Disease	lung non-small cell carcinoma (is_implicated_in)	ABCB1 EGFR ABCC2 SDHA	2.62e-03	139	121	4	DOID:3908 (is_implicated_in)
Disease	end stage renal disease (implicated_via_orthology)	ABCB1 ABCC2	3.02e-03	20	121	2	DOID:783 (implicated_via_orthology)
Disease	aspartate aminotransferase to alanine aminotransferase ratio	EPPK1 ANPEP ABCB1 SF3B3 ABCC2	3.10e-03	239	121	5	EFO_0010934
Disease	adiponectin measurement	HIVEP2 LLGL1 HERC2 RAPGEF2	3.12e-03	146	121	4	EFO_0004502
Disease	cardiomyopathy (implicated_via_orthology)	ITGA7 EGFR SDHA	3.14e-03	71	121	3	DOID:0050700 (implicated_via_orthology)
Disease	mean platelet volume	HSCB HIVEP2 TRMO RSPH6A ALG9 SYNE2 PLCB1 RIPOR1 NR3C2 PHIP FBXO34	3.21e-03	1020	121	11	EFO_0004584
Disease	rheumatoid arthritis, ulcerative colitis	EMSY SNAPC4	3.33e-03	21	121	2	EFO_0000685, EFO_0000729
Disease	chronic myeloid leukemia (is_implicated_in)	ABCB1 ABCC2	3.33e-03	21	121	2	DOID:8552 (is_implicated_in)
Disease	Alzheimer disease, educational attainment	ATXN2L ST3GAL3 ABCA7 BCAR3 EPHA1	3.57e-03	247	121	5	EFO_0011015, MONDO_0004975
Disease	Colonic Neoplasms	ITGA7 EGFR PLCB1 EIF3I	3.61e-03	152	121	4	C0009375
Disease	cholangiocarcinoma (is_implicated_in)	PREX2 ABCC2	3.65e-03	22	121	2	DOID:4947 (is_implicated_in)
Disease	ATRIAL FIBRILLATION, FAMILIAL, 1 (disorder)	SCN2B SCN5A	3.65e-03	22	121	2	C1843687
Disease	otitis media (implicated_via_orthology)	SALL4 SH3PXD2B	3.65e-03	22	121	2	DOID:10754 (implicated_via_orthology)
Disease	Paroxysmal atrial fibrillation	USP34 GOPC SYNE2 SCN5A	3.96e-03	156	121	4	C0235480
Disease	familial atrial fibrillation	USP34 GOPC SYNE2 SCN5A	3.96e-03	156	121	4	C3468561
Disease	Persistent atrial fibrillation	USP34 GOPC SYNE2 SCN5A	3.96e-03	156	121	4	C2585653
Disease	Hereditary Paraganglioma-Pheochromocytoma Syndrome	MITF SDHA	3.99e-03	23	121	2	C1708353
Disease	level of Sphingomyelin (d40:2) in blood serum	SYNE2 ANKRD17	3.99e-03	23	121	2	OBA_2045181
Disease	Esophageal Neoplasms	ABCB1 EGFR UCHL1	4.09e-03	78	121	3	C0014859
Disease	Malignant neoplasm of esophagus	ABCB1 EGFR UCHL1	4.09e-03	78	121	3	C0546837

Protein segments in the cluster

Peptide	Gene	Start	Entry
LLASREALYNEMDPD	CACNA1A	786	O00555
YMESDQDVGIQLRRP	EPHA1	126	P21709
MNLVQGTREEGYTDP	ANXA10	156	Q9UJ72
EQMPEYRGRATLVQD	BTN1A1	86	Q13410
AERILAGFQPDEEMN	BCAR3	761	O75815
EERLLADLMQNYDPN	CHRNG	26	P07510
RLYDPDDGFIMVDEN	ABCB5	436	Q2M3G0
MNDQNLEEPSRYIDI	ALG9	516	Q9H6U8
AENEFNETLRPGYEM	DEPDC4	176	Q8N2C3
NRYDVEMTDELVGLP	FBXO34	401	Q9NWN3
REIPENLMDQYSEVN	ANPEP	741	P15144
ASLEEVNDEGYTPLM	ANKRD17	491	O75179
VNDEGYTPLMEAARE	ANKRD17	496	O75179
SPQYRLRIAMENDDG	ATXN2L	306	Q8WWM7
YEASDLMELVGQEPE	ABCA7	241	Q8IZY2
EEDYSGLTEDMLLPR	BAZ1A	826	Q9NRL2
YDQREMILNPEGDVN	RBM12	526	Q9NTZ6
DMYAEQTENPENPLR	QRICH1	686	Q2TAL8
MQLDPETVDNLDAYS	PTPN23	401	Q9H3S7
DPDQADITYEGRQKM	GOPC	56	Q9HD26
RMNLDPFGSYSEEDI	ABCC3	1381	O15438
PYEASRDLAQAPDMQ	LLGL1	806	Q15334
QRLYDPTEGMVSVDG	ABCB1	441	P08183
PRLADTYEMLAIEGA	GGT3P	211	A6NGU5
ITNLQYEEDMRRPGS	MUC16	13331	Q8WXI7
EENENGERTPYLIVM	PCDH20	261	Q8N6Y1
MVVDQGDPRLLLDSY	PAK6	396	Q9NQU5
LGPTERTDENNYMEI	NR3C2	31	P08235
YTPSEAGNELDMELG	MAF1	211	Q9H063
ASMEQLLREQPGEEY	NEK1	1111	Q96PY6
EGQLMPRYEELAESV	INTS1	311	Q8N201
PGLMYIRDNEATSEE	HERC2	4581	O95714
QDMEQLAPEIRSYED	HEMK1	246	Q9Y5R4
PDLGDNALMAYSILD	CDH24	286	Q86UP0
EKINSDYLRDGINMP	FAM135A	1131	Q9P2D6
DDGIERTHPDLMQNY	PCSK5	171	Q92824
NDLDPMPRYDASNEN	PCSK5	196	Q92824
NPLYGDLSLEEAMEE	MINAR2	91	P59773
EEYNELMVRNGDPRI	PDZD2	516	O15018
VGRSMQQLLDYPEDD	HERC4	841	Q5GLZ8
MEEGQYSEIEELPRR	FCER2	1	P06734
LRMNLDPFNNYSDEE	ABCC2	1391	Q92887
VDNTRMDLIIPGEQY	PLEKHA8	56	Q96JA3
MNLDGSAQDPEKREY	RFESD	1	Q8TAC1
MIPEEADYVGIERNN	ITGA8	691	P53708
EPEGRDLLMQLLQYD	CDK3	256	Q00526
MARDPQRYLVIQGDE	EGFR	971	P00533
ELDSGAEGLMEQNYP	FHIP1A	761	Q05DH4
PEDVQALMYLRGQLE	HDAC10	641	Q969S8
SLQREGMGSPAYEQD	HYLS1	171	Q96M11
LRVLSMGPEDEGVYQ	BOC	376	Q9BWV1
DMERQGDVYRQGTTP	ADAR	336	P55265
MYQSLQGNDLLEDSP	GFRA1	106	P56159
MLERAGVENQEYTGP	AXDND1	231	Q5T1B0
DLRDPSQIDNNEPYM	EIF3I	126	Q13347
DSDGQVSVYELRNMP	DNAI4	811	Q5VTH9
EMNSVLEILYPRDED	CRTAC1	521	Q9NQ79
LDMDGNQYPDLLVGS	ITGA7	491	Q13683
EEMDTLDPQTGLFYR	EMSY	926	Q7Z589
DYNRIIAMLSPDEQA	DNAH2	681	Q9P225
PELSQYMGLSLNEEE	SDCBP	51	O00560
LMGDQEYQSRSPDIL	SALL4	766	Q9UJQ4
PRLADTYEMLAIEGA	GGT2P	211	P36268
ESGYERRPLEMEQQQ	HNRNPUL1	121	Q9BUJ2
NGEPNMEDDRYRLML	KIF17	926	Q9P2E2
YQADIPEMLLEGESD	MTA3	156	Q9BTC8
GIEIPERTDYEMDRQ	HSCB	146	Q8IWL3
AILDNLPVGYEAEMS	FER1L6	791	Q2WGJ9
QAEEARLGGMEYPSV	RSPH6A	76	Q9H0K4
YPDATPEELQAMDNV	SYVN1	276	Q86TM6
SRMLNYIEQEVIGPD	ROPN1B	181	Q9BZX4
GEVQIAMEPQALYDE	SMCHD1	646	A6NHR9
SPGEARLTNLEYMLE	TEX14	386	Q8IWB6
YEEAMQGPAARLVAS	TAGAP	596	Q8N103
LEMPRLYREDGSGQQ	SYNE2	4551	Q8WXH0
VELENYGMPFSRTED	SDHA	151	P31040
DYLREAPEDIQDLMD	GIMAP4	166	Q9NUV9
GYFDEEMNRVLADPS	EPPK1	2366	P58107
RGYFDEEMNRVLADP	EPPK1	2901	P58107
RGYFDEEMNRVLADP	EPPK1	3966	P58107
LEGSMDGEEQAPQLY	NEU1	376	Q99519
APEREGLIAYVMSEN	SCN5A	1941	Q14524
DVRKSDVEYENGPQM	KIAA1217	1186	Q5T5P2
AAMREAGTALPDQYQ	SIKE1	41	Q9BRV8
EGAMQRPEQYERDSL	ST3GAL3	211	Q11203
MVGEGPYLISDLDQR	ABCC12	1	Q96J65
NSEELREIMGTPEYV	STK17A	216	Q9UEE5
TLVEQNPEDMGDLYL	GTF3C3	411	Q9Y5Q9
DERGQELIYAGMPIT	ACLY	846	P53396
EVNDEGYTPLMEAAR	ANKHD1	466	Q8IWZ3
DPARGMEYTLDLQLE	CHPF	456	Q8IZ52
AEEGMEPRALQYEQT	CLCN2	6	P51788
AERAYEETRMLDGQP	C11orf42	106	Q8N5U0
GDPAMTRFLEEFENN	RAPGEF2	346	Q9Y4G8
SVMLRNVQPEDEGIY	SCN2B	111	O60939
AEYDSPQNVMEPLAD	TRMO	161	Q9BU70
ALPRLGYSDAEMDEQ	ZSCAN20	426	P17040
SYNEEILGLMDPALQ	MITF	236	O75030
VRETLEAGNYESPME	PHIP	1366	Q8WWQ0
YGMFDGDRNEELPRL	PHLPP2	816	Q6ZVD8
PYTARDQDEMNLERG	SH3PXD2B	231	A1X283
EQMLDPREQSYLGTL	ZBTB41	876	Q5SVQ8
NPDGMVALLDYREDG	TPT1	141	P13693
GDATNPDRMYDLVAV	USP12	291	O75317
GYLRGNMSENEEEEI	ZNF768	26	Q9H5H4
DGTFYPRNEMQDVIS	PREX2	466	Q70Z35
GTRPPINMEELDESY	PBK	276	Q96KB5
NEERFDSYPMVLGAQ	TRIM21	321	P19474
FEMDPSGQLNEYTER	SF3B3	566	Q15393
MRYLSGEENGVVSPE	PLCB1	296	Q9NQ66
GYREDNVPQLEDVSM	TPH2	251	Q8IWU9
EAIASRMEDYLQLPD	YLPM1	2071	P49750
QVDLIDMQLNPDGEY	ZBED9	376	Q6R2W3
QAGEGDRALLSPQYM	SNAPC4	551	Q5SXM2
YDDETMELILPSGAR	ZNF622	376	Q969S3
DPEAEVLLAYEMNGQ	SUOX	341	P51687
IEMYPSDQVADLRAE	USP34	1226	Q70CQ2
NLNLLPGMSEDGVEY	WDR33	416	Q9C0J8
DEDMLYSPELAQRGH	WBP11	231	Q9Y2W2
SDYDPKLQMQEGVRS	HIVEP2	726	P31629
LMAALDDYRGQFPEL	RIPOR1	801	Q6ZS17
GDRYDFPLLQAELAM	TREX1	126	Q9NSU2
NETLAEMEEELRYAP	VTI1B	56	Q9UEU0
EYLLDRLPEMGSNVE	TRRAP	691	Q9Y4A5
EDEYMDRPSQPTDQL	TNFRSF11A	346	Q9Y6Q6
NNVDGHLYELDGRMP	UCHL1	166	P09936
DPAQRDLYVDVMLEN	ZNF283	91	Q8N7M2
YRDINEIDINMNDPL	PCSK2	111	P16519