Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	UDP-galactose:glucosylceramide beta-1,4-galactosyltransferase activity	B4GALT6 B4GALT5	6.56e-05	3	94	2	GO:0008489
GeneOntologyMolecularFunction	endopeptidase activity	PRSS12 CTRB2 ADAMTS7 TPP1 ADAMTS16 ADAMTS18 RHBDD3 CTRB1 MMP26	1.94e-04	430	94	9	GO:0004175
GeneOntologyMolecularFunction	N-acetyllactosamine synthase activity	B4GALT5 B4GALT1	2.17e-04	5	94	2	GO:0003945
GeneOntologyMolecularFunction	UDP-galactosyltransferase activity	B4GALT6 B4GALT5 B4GALT1	4.54e-04	32	94	3	GO:0035250
GeneOntologyMolecularFunction	galactosyltransferase activity	B4GALT6 B4GALT5 B4GALT1	5.93e-04	35	94	3	GO:0008378
GeneOntologyBiologicalProcess	positive regulation of nuclear-transcribed mRNA poly(A) tail shortening	CPEB3 TNRC6B TNRC6C TNRC6A	3.43e-07	14	91	4	GO:0060213
GeneOntologyBiologicalProcess	regulation of nuclear-transcribed mRNA poly(A) tail shortening	CPEB3 TNRC6B TNRC6C TNRC6A	6.20e-07	16	91	4	GO:0060211
GeneOntologyBiologicalProcess	nuclear-transcribed mRNA poly(A) tail shortening	CPEB3 TNRC6B TNRC6C TNRC6A	1.32e-05	33	91	4	GO:0000289
GeneOntologyBiologicalProcess	positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay	CPEB3 TNRC6B TNRC6C	4.46e-05	16	91	3	GO:1900153
Domain	Ago_hook	TNRC6B TNRC6C TNRC6A	1.05e-07	3	89	3	PF10427
Domain	TNRC6_PABC-bd	TNRC6B TNRC6C TNRC6A	1.05e-07	3	89	3	IPR032226
Domain	Argonaute_hook_dom	TNRC6B TNRC6C TNRC6A	1.05e-07	3	89	3	IPR019486
Domain	TNRC6-PABC_bdg	TNRC6B TNRC6C TNRC6A	1.05e-07	3	89	3	PF16608
Domain	Galactosyl_T	B4GALT6 B4GALT5 B4GALT1	3.61e-06	7	89	3	IPR003859
Domain	Glyco_transf_7C	B4GALT6 B4GALT5 B4GALT1	3.61e-06	7	89	3	PF02709
Domain	Glyco_transf_7N	B4GALT6 B4GALT5 B4GALT1	3.61e-06	7	89	3	PF13733
Domain	Galactosyl_T_C	B4GALT6 B4GALT5 B4GALT1	3.61e-06	7	89	3	IPR027791
Domain	Galactosyl_T_N	B4GALT6 B4GALT5 B4GALT1	3.61e-06	7	89	3	IPR027995
Domain	UBA-like	TNRC6B TNRC6C VPS13D TNRC6A RHBDD3	1.34e-05	64	89	5	IPR009060
Domain	M_domain	TNRC6C TNRC6A	2.25e-05	2	89	2	PF12938
Domain	GW182_M_dom	TNRC6C TNRC6A	2.25e-05	2	89	2	IPR026805
Domain	CYSTEINE_SWITCH	ADAMTS7 ADAMTS16 ADAMTS18 MMP26	4.26e-05	41	89	4	PS00546
Domain	Pept_M10_metallopeptidase	ADAMTS7 ADAMTS16 ADAMTS18 MMP26	5.16e-05	43	89	4	IPR001818
Domain	FAD-linked_oxidoreductase-like	PRODH2 MTHFR	6.72e-05	3	89	2	IPR029041
Domain	-	PRODH2 MTHFR	6.72e-05	3	89	2	3.20.20.220
Domain	PLAC	ADAMTS7 ADAMTS16 ADAMTS18	9.59e-05	19	89	3	PS50900
Domain	PLAC	ADAMTS7 ADAMTS16 ADAMTS18	9.59e-05	19	89	3	IPR010909
Domain	Long_hematopoietin_rcpt_CS	MPL EPOR	1.34e-04	4	89	2	IPR003528
Domain	HEMATOPO_REC_L_F1	MPL EPOR	1.34e-04	4	89	2	PS01352
Domain	ADAM_spacer1	ADAMTS7 ADAMTS16 ADAMTS18	1.73e-04	23	89	3	IPR010294
Domain	ADAM_spacer1	ADAMTS7 ADAMTS16 ADAMTS18	1.73e-04	23	89	3	PF05986
Domain	Peptidase_M12B_ADAM-TS	ADAMTS7 ADAMTS16 ADAMTS18	1.97e-04	24	89	3	IPR013273
Domain	Growth/epo_recpt_lig-bind	MPL EPOR	2.22e-04	5	89	2	IPR015152
Domain	EpoR_lig-bind	MPL EPOR	2.22e-04	5	89	2	PF09067
Domain	APC_su10/DOC_dom	CUL9 ZZEF1	4.64e-04	7	89	2	IPR004939
Domain	DOC	CUL9 ZZEF1	4.64e-04	7	89	2	PS51284
Domain	APC10	CUL9 ZZEF1	4.64e-04	7	89	2	SM01337
Domain	ANAPC10	CUL9 ZZEF1	4.64e-04	7	89	2	PF03256
Domain	MetalloPept_cat_dom	ADAMTS7 ADAMTS16 ADAMTS18 MMP26	6.06e-04	81	89	4	IPR024079
Domain	-	ADAMTS7 ADAMTS16 ADAMTS18 MMP26	6.06e-04	81	89	4	3.40.390.10
Domain	UBA	TNRC6C VPS13D RHBDD3	6.67e-04	36	89	3	PF00627
Domain	Peptidase_M12B_N	ADAMTS7 ADAMTS16 ADAMTS18	8.44e-04	39	89	3	IPR002870
Domain	Pep_M12B_propep	ADAMTS7 ADAMTS16 ADAMTS18	8.44e-04	39	89	3	PF01562
Domain	DISINTEGRIN_1	ADAMTS7 ADAMTS16 ADAMTS18	9.10e-04	40	89	3	PS00427
Domain	Reprolysin	ADAMTS7 ADAMTS16 ADAMTS18	9.10e-04	40	89	3	PF01421
Domain	ADAM_MEPRO	ADAMTS7 ADAMTS16 ADAMTS18	9.10e-04	40	89	3	PS50215
Domain	DISINTEGRIN_2	ADAMTS7 ADAMTS16 ADAMTS18	9.10e-04	40	89	3	PS50214
Domain	Peptidase_M12B	ADAMTS7 ADAMTS16 ADAMTS18	9.10e-04	40	89	3	IPR001590
Domain	Disintegrin_dom	ADAMTS7 ADAMTS16 ADAMTS18	9.78e-04	41	89	3	IPR001762
Domain	UBA	TNRC6C VPS13D RHBDD3	1.20e-03	44	89	3	IPR015940
Domain	ZINC_PROTEASE	ADAMTS7 ADAMTS16 ADAMTS18 MMP26	1.24e-03	98	89	4	PS00142
Domain	UBA	TNRC6C VPS13D RHBDD3	1.46e-03	47	89	3	PS50030
Domain	PLAC	ADAMTS16 ADAMTS18	1.97e-03	14	89	2	PF08686
Domain	TSP_1	ADAMTS7 ADAMTS16 ADAMTS18	3.38e-03	63	89	3	PF00090
Domain	TSP1	ADAMTS7 ADAMTS16 ADAMTS18	3.69e-03	65	89	3	SM00209
Domain	TSP1_rpt	ADAMTS7 ADAMTS16 ADAMTS18	3.69e-03	65	89	3	IPR000884
Domain	TSP1	ADAMTS7 ADAMTS16 ADAMTS18	3.69e-03	65	89	3	PS50092
Domain	-	MANBA CUL9 ZZEF1	5.11e-03	73	89	3	2.60.120.260
Domain	-	B4GALT6 B4GALT5 B4GALT1	6.83e-03	81	89	3	3.90.550.10
Domain	Nucleotide-bd_a/b_plait	CPEB3 TNRC6B DGKQ TNRC6C TNRC6A	7.83e-03	258	89	5	IPR012677
Domain	Nucleotide-diphossugar_trans	B4GALT6 B4GALT5 B4GALT1	8.57e-03	88	89	3	IPR029044
Domain	UBA	TNRC6C VPS13D	8.96e-03	30	89	2	SM00165
Domain	TRYPSIN_SER	PRSS12 CTRB2 CTRB1	9.12e-03	90	89	3	IPR033116
Pathway	REACTOME_POST_TRANSCRIPTIONAL_SILENCING_BY_SMALL_RNAS	TNRC6B TNRC6C TNRC6A	2.53e-06	7	60	3	M46421
Pathway	REACTOME_REGULATION_OF_PTEN_MRNA_TRANSLATION	TNRC6B TNRC6C TNRC6A	6.05e-06	9	60	3	M27810
Pathway	REACTOME_REGULATION_OF_NPAS4_MRNA_TRANSLATION	TNRC6B TNRC6C TNRC6A	6.05e-06	9	60	3	M46436
Pathway	REACTOME_O_LINKED_GLYCOSYLATION	B4GALT6 B4GALT5 ADAMTS7 ADAMTS16 ADAMTS18 POFUT2	6.64e-06	109	60	6	MM15164
Pathway	REACTOME_O_LINKED_GLYCOSYLATION	B4GALT6 B4GALT5 ADAMTS7 ADAMTS16 ADAMTS18 POFUT2	7.37e-06	111	60	6	M27416
Pathway	REACTOME_REGULATION_OF_CDH11_MRNA_TRANSLATION_BY_MICRORNAS	TNRC6B TNRC6C TNRC6A	8.61e-06	10	60	3	M48013
Pathway	REACTOME_REGULATION_OF_NPAS4_GENE_EXPRESSION	TNRC6B TNRC6C TNRC6A	2.03e-05	13	60	3	M46434
Pathway	REACTOME_O_GLYCOSYLATION_OF_TSR_DOMAIN_CONTAINING_PROTEINS	ADAMTS7 ADAMTS16 ADAMTS18 POFUT2	2.18e-05	39	60	4	M27417
Pathway	REACTOME_O_GLYCOSYLATION_OF_TSR_DOMAIN_CONTAINING_PROTEINS	ADAMTS7 ADAMTS16 ADAMTS18 POFUT2	2.18e-05	39	60	4	MM15165
Pathway	REACTOME_N_GLYCAN_ANTENNAE_ELONGATION	B4GALT6 B4GALT5 B4GALT1	3.22e-05	15	60	3	M966
Pathway	REACTOME_N_GLYCAN_ANTENNAE_ELONGATION	B4GALT6 B4GALT5 B4GALT1	3.22e-05	15	60	3	MM15700
Pathway	REACTOME_REGULATION_OF_RUNX1_EXPRESSION_AND_ACTIVITY	TNRC6B TNRC6C TNRC6A	4.78e-05	17	60	3	M27788
Pathway	REACTOME_REGULATION_OF_MITF_M_DEPENDENT_GENES_INVOLVED_IN_APOPTOSIS	TNRC6B TNRC6C TNRC6A	6.77e-05	19	60	3	M48238
Pathway	REACTOME_TRANSCRIPTIONAL_REGULATION_BY_MECP2	TNRC6B TNRC6C OPRK1 TNRC6A	1.46e-04	63	60	4	M27862
Pathway	REACTOME_N_GLYCAN_ANTENNAE_ELONGATION_IN_THE_MEDIAL_TRANS_GOLGI	B4GALT6 B4GALT5 B4GALT1	1.78e-04	26	60	3	M979
Pathway	REACTOME_KERATAN_SULFATE_BIOSYNTHESIS	B4GALT6 B4GALT5 B4GALT1	2.23e-04	28	60	3	M670
Pathway	REACTOME_TGFBR3_EXPRESSION	TNRC6B TNRC6C TNRC6A	2.23e-04	28	60	3	M48253
Pathway	REACTOME_KERATAN_SULFATE_BIOSYNTHESIS	B4GALT6 B4GALT5 B4GALT1	2.23e-04	28	60	3	MM14798
Pathway	REACTOME_N_GLYCAN_ANTENNAE_ELONGATION_IN_THE_MEDIAL_TRANS_GOLGI	B4GALT6 B4GALT5 B4GALT1	2.48e-04	29	60	3	MM15699
Pathway	REACTOME_POST_TRANSCRIPTIONAL_SILENCING_BY_SMALL_RNAS	TNRC6B TNRC6A	2.64e-04	6	60	2	MM15083
Pathway	REACTOME_REGULATION_OF_HOMOTYPIC_CELL_CELL_ADHESION	TNRC6B TNRC6C TNRC6A	3.33e-04	32	60	3	M48012
Pathway	REACTOME_REGULATION_OF_MECP2_EXPRESSION_AND_ACTIVITY	TNRC6B TNRC6C TNRC6A	3.33e-04	32	60	3	M27900
Pathway	REACTOME_TRANSCRIPTIONAL_REGULATION_BY_NPAS4	TNRC6B TNRC6C TNRC6A	3.99e-04	34	60	3	M46422
Pathway	REACTOME_ONCOGENE_INDUCED_SENESCENCE	TNRC6B TNRC6C TNRC6A	4.35e-04	35	60	3	M27190
Pathway	REACTOME_KERATAN_SULFATE_KERATIN_METABOLISM	B4GALT6 B4GALT5 B4GALT1	4.74e-04	36	60	3	M690
Pathway	REACTOME_KERATAN_SULFATE_KERATIN_METABOLISM	B4GALT6 B4GALT5 B4GALT1	4.74e-04	36	60	3	MM14632
Pathway	REACTOME_NR1H3_NR1H2_REGULATE_GENE_EXPRESSION_LINKED_TO_CHOLESTEROL_TRANSPORT_AND_EFFLUX	TNRC6B TNRC6C TNRC6A	5.14e-04	37	60	3	M29790
Pathway	REACTOME_TRANSCRIPTIONAL_REGULATION_BY_VENTX	TNRC6B TNRC6C TNRC6A	6.96e-04	41	60	3	M29748
Pathway	REACTOME_UPTAKE_OF_DIETARY_COBALAMINS_INTO_ENTEROCYTES	CTRB2 CTRB1	7.84e-04	10	60	2	M45024
Pathway	REACTOME_NR1H2_AND_NR1H3_MEDIATED_SIGNALING	TNRC6B TNRC6C TNRC6A	1.04e-03	47	60	3	M29777
Pathway	REACTOME_GENE_SILENCING_BY_RNA	NUP88 TNRC6B TNRC6A	1.18e-03	49	60	3	MM14837
Pathway	REACTOME_SIGNALING_BY_TGFBR3	TNRC6B TNRC6C TNRC6A	1.18e-03	49	60	3	M48250
Pathway	REACTOME_GLYCOSPHINGOLIPID_METABOLISM	ARSI B4GALT6 B4GALT5	1.48e-03	53	60	3	MM14647
Pathway	REACTOME_PRE_NOTCH_EXPRESSION_AND_PROCESSING	TNRC6B TNRC6C B4GALT1 TNRC6A	1.64e-03	119	60	4	M607
Pathway	REACTOME_GLYCOSPHINGOLIPID_METABOLISM	ARSI B4GALT6 B4GALT5	1.92e-03	58	60	3	M576
Pathway	REACTOME_ADHERENS_JUNCTIONS_INTERACTIONS	TNRC6B TNRC6C TNRC6A	1.92e-03	58	60	3	M11980
Pathway	KEGG_OTHER_GLYCAN_DEGRADATION	MANBA FUCA2	2.06e-03	16	60	2	M17844
Pathway	REACTOME_METABOLISM_OF_WATER_SOLUBLE_VITAMINS_AND_COFACTORS	CTRB2 MTHFR CTRB1 NAXE	2.07e-03	127	60	4	M27093
Pathway	REACTOME_CA2_PATHWAY	TNRC6B TNRC6C TNRC6A	2.32e-03	62	60	3	M27321
Pathway	KEGG_MEDICUS_REFERENCE_HORMONE_LIKE_CYTOKINE_TO_JAK_STAT_SIGNALING_PATHWAY	MPL EPOR	2.33e-03	17	60	2	M47905
Pathway	REACTOME_GENE_SILENCING_BY_RNA	NUP88 TNRC6B TNRC6C TNRC6A	2.88e-03	139	60	4	M715
Pathway	REACTOME_GLYCOSPHINGOLIPID_BIOSYNTHESIS	B4GALT6 B4GALT5	2.91e-03	19	60	2	MM17075
Pathway	REACTOME_GLYCOSPHINGOLIPID_BIOSYNTHESIS	B4GALT6 B4GALT5	2.91e-03	19	60	2	M48041
Pathway	REACTOME_DEGRADATION_OF_THE_EXTRACELLULAR_MATRIX	CTRB2 ADAMTS16 ADAMTS18 CTRB1	2.95e-03	140	60	4	M587
Pathway	REACTOME_DISEASES_ASSOCIATED_WITH_O_GLYCOSYLATION_OF_PROTEINS	ADAMTS7 ADAMTS16 ADAMTS18	3.02e-03	68	60	3	M27303
Pathway	REACTOME_DISEASES_OF_GLYCOSYLATION	B4GALT1 ADAMTS7 ADAMTS16 ADAMTS18	3.19e-03	143	60	4	M27275
Pathway	WP_GLYCOSPHINGOLIPID_METABOLISM	B4GALT6 B4GALT5	3.55e-03	21	60	2	M46462
Pathway	REACTOME_COBALAMIN_CBL_VITAMIN_B12_TRANSPORT_AND_METABOLISM	CTRB2 CTRB1	3.90e-03	22	60	2	M27084
Pubmed	Nucleotide sequence of the partially deleted D4Z4 locus in a patient with FSHD identifies a putative gene within each 3.3 kb element.	DUX4L9 DUX4L2 DUX4 DUX4L5 DUX4L6 DUX4L3 DUX4L4 DUX4L7	1.72e-18	12	100	8	10433963
Pubmed	Evolutionary conservation of a coding function for D4Z4, the tandem DNA repeat mutated in facioscapulohumeral muscular dystrophy.	DUX4L9 DUX4L2 DUX4 DUX4L5 DUX4L6 DUX4L3 DUX4L4 DUX4L7	4.46e-18	13	100	8	17668377
Pubmed	The DUX4 gene at the FSHD1A locus encodes a pro-apoptotic protein.	DUX4L2 DUX4 DUX4L5 DUX4L6 DUX4L3 DUX4L4 DUX4L7	1.05e-17	8	100	7	17588759
Pubmed	DUX4, a candidate gene of facioscapulohumeral muscular dystrophy, encodes a transcriptional activator of PITX1.	DUX4L2 DUX4 DUX4L5 DUX4L6 DUX4L3 DUX4L4 DUX4L7	1.56e-16	10	100	7	17984056
Pubmed	Characterization of a tandemly repeated 3.3-kb KpnI unit in the facioscapulohumeral muscular dystrophy (FSHD) gene region on chromosome 4q35.	DUX4L2 DUX4 DUX4L5 DUX4L6 DUX4L3 DUX4L4 DUX4L7	2.22e-15	13	100	7	7739628
Pubmed	Active genes in junk DNA? Characterization of DUX genes embedded within 3.3 kb repeated elements.	DUX4L2 DUX4 DUX4L5 DUX4L6 DUX4L3 DUX4L4 DUX4L7	2.49e-14	17	100	7	11245978
Pubmed	Impact of scaffolding protein TNRC6 paralogs on gene expression and splicing.	TNRC6B TNRC6C TNRC6A	2.31e-08	3	100	3	34108231
Pubmed	Gawky is a component of cytoplasmic mRNA processing bodies required for early Drosophila development.	TNRC6B TNRC6C TNRC6A	2.31e-08	3	100	3	16880270
Pubmed	Expression of TNRC6 (GW182) Proteins Is Not Necessary for Gene Silencing by Fully Complementary RNA Duplexes.	TNRC6B TNRC6C TNRC6A	2.31e-08	3	100	3	31670606
Pubmed	The homeobox transcription factor DUXBL controls exit from totipotency.	DUX4L9 DUX4L2 DUX4L4	9.21e-08	4	100	3	38509386
Pubmed	Expression profiling of immature thymocytes revealed a novel homeobox gene that regulates double-negative thymocyte development.	DUX4L9 DUX4L2 DUX4L4	9.21e-08	4	100	3	17911620
Pubmed	Two PABPC1-binding sites in GW182 proteins promote miRNA-mediated gene silencing.	TNRC6B TNRC6C TNRC6A	9.21e-08	4	100	3	21063388
Pubmed	Characterization of genomic structures and expression profiles of three tandem repeats of a mouse double homeobox gene: Duxbl.	DUX4L9 DUX4L2 DUX4L4	2.30e-07	5	100	3	20063414
Pubmed	The expanding beta 4-galactosyltransferase gene family: messages from the databanks.	B4GALT6 B4GALT5 B4GALT1	4.58e-07	6	100	3	9597550
Pubmed	Functional dissection of the human TNRC6 (GW182-related) family of proteins.	TNRC6B TNRC6C TNRC6A	8.01e-07	7	100	3	19470757
Pubmed	The C-terminal domains of human TNRC6A, TNRC6B, and TNRC6C silence bound transcripts independently of Argonaute proteins.	TNRC6B TNRC6C TNRC6A	8.01e-07	7	100	3	19383768
Pubmed	The transcription factor Duxbl mediates elimination of pre-T cells that fail β-selection.	DUX4L9 DUX4L2 DUX4L4	8.01e-07	7	100	3	30765463
Pubmed	Role of GW182 protein in the cell.	TNRC6B TNRC6A	8.18e-06	2	100	2	29791863
Pubmed	Chymotrypsin Reduces the Severity of Secretagogue-Induced Pancreatitis in Mice.	CTRB2 CTRB1	8.18e-06	2	100	2	30076839
Pubmed	The CTRB1-CTRB2 risk allele for chronic pancreatitis discovered in European populations does not contribute to disease risk variation in the Chinese population due to near allele fixation.	CTRB2 CTRB1	8.18e-06	2	100	2	28951524
Pubmed	β4GalT6 is involved in the synthesis of lactosylceramide with less intensity than β4GalT5.	B4GALT6 B4GALT5	8.18e-06	2	100	2	23882130
Pubmed	Genome-wide association study identifies inversion in the CTRB1-CTRB2 locus to modify risk for alcoholic and non-alcoholic chronic pancreatitis.	CTRB2 CTRB1	8.18e-06	2	100	2	28754779
Pubmed	Sequencing of the complex CTRB1-CTRB2 locus in chronic pancreatitis.	CTRB2 CTRB1	8.18e-06	2	100	2	33036922
Pubmed	Establishment of HeLa cell mutants deficient in sphingolipid-related genes using TALENs.	B4GALT6 B4GALT5	8.18e-06	2	100	2	24498430
Pubmed	B4GALT family mediates the multidrug resistance of human leukemia cells by regulating the hedgehog pathway and the expression of p-glycoprotein and multidrug resistance-associated protein 1.	B4GALT5 B4GALT1	8.18e-06	2	100	2	23744354
Pubmed	Evolutionary relationships between laboratory mice and subspecies of Mus musculus based on the restriction fragment length variants of the chymotrypsin gene at the Prt-2 locus.	CTRB2 CTRB1	8.18e-06	2	100	2	2565717
Pubmed	Differential transcriptomic changes in the central nervous system and urinary bladders of mice infected with a coronavirus.	ZBP1 SIGLEC1	8.18e-06	2	100	2	36490282
Pubmed	Molecular cloning and nucleotide sequence of human pancreatic prechymotrypsinogen cDNA.	CTRB2 CTRB1	8.18e-06	2	100	2	2917002
Pubmed	Genomic cloning and partial characterization of human chymotrypsinogen gene.	CTRB2 CTRB1	8.18e-06	2	100	2	8186414
Pubmed	Defective regulation of microRNA target genes in myoblasts from facioscapulohumeral dystrophy patients.	DUX4L9 DUX4	8.18e-06	2	100	2	24145033
Pubmed	Genetic heterogeneity in Leigh syndrome: Highlighting treatable and novel genetic causes.	VPS13D NAXE	8.18e-06	2	100	2	32020600
Pubmed	Evaluation of ADAMTS12, ADAMTS16, ADAMTS18 and IL-33 serum levels in pre-eclampsia.	ADAMTS16 ADAMTS18	8.18e-06	2	100	2	26382559
Pubmed	[EPOR and TPOR expressions on CD34+ CD59- and CD34+ CD59+ bone marrow cells from patients with paroxysmal nocturnal hemoglobinuria].	MPL EPOR	8.18e-06	2	100	2	22338178
Pubmed	Lactosylceramide synthases encoded by B4galt5 and 6 genes are pivotal for neuronal generation and myelin formation in mice.	B4GALT6 B4GALT5	8.18e-06	2	100	2	30114188
Pubmed	Mammalian miRNA RISC recruits CAF1 and PABP to affect PABP-dependent deadenylation.	TNRC6B TNRC6C TNRC6A	8.20e-06	14	100	3	19716330
Pubmed	Mutations in MINAR2 encoding membrane integral NOTCH2-associated receptor 2 cause deafness in humans and mice.	DUX4L9 DUX4L2 DUX4L4	1.02e-05	15	100	3	35727972
Pubmed	Proteomic analysis identifies transcriptional cofactors and homeobox transcription factors as TBX18 binding proteins.	DUX4L9 DUX4L2 DUX4L4	1.02e-05	15	100	3	30071041
Pubmed	GW182 proteins directly recruit cytoplasmic deadenylase complexes to miRNA targets.	TNRC6B TNRC6C TNRC6A	1.02e-05	15	100	3	21981923
Pubmed	Identification and characterization of large galactosyltransferase gene families: galactosyltransferases for all functions.	B4GALT6 B4GALT5 B4GALT1	1.26e-05	16	100	3	10580128
Pubmed	Regulation of astrocyte activation by glycolipids drives chronic CNS inflammation.	B4GALT6 B4GALT5	2.45e-05	3	100	2	25216636
Pubmed	Genetic study of pancreatic proteinase in mice (Mus musculus): linkage of the Prt-2 locus on chromosome 8.	CTRB2 CTRB1	2.45e-05	3	100	2	1016231
Pubmed	Secretagogue-induced pancreatitis in mice devoid of chymotrypsin.	CTRB2 CTRB1	2.45e-05	3	100	2	38981616
Pubmed	[STAT5 phosphorylation levels of erythropoietin and thrombopoietin receptors in CD34(+)CD59(-) and CD34(+)CD59(+) bone marrow cells of patients with paroxysmal nocturnal hemoglobinuria].	MPL EPOR	2.45e-05	3	100	2	22093990
Pubmed	Genetic study of pancreatic proteinase in mice (Mus musculus): genetic variants of trypsin and chymotrypsin.	CTRB2 CTRB1	2.45e-05	3	100	2	1008801
Pubmed	Evolutionary expansion of polyaspartate motif in the activation peptide of mouse cationic trypsinogen limits autoactivation and protects against pancreatitis.	CTRB2 CTRB1	2.45e-05	3	100	2	34643096
Pubmed	Loss of chymotrypsin-like protease (CTRL) alters intrapancreatic protease activation but not pancreatitis severity in mice.	CTRB2 CTRB1	2.45e-05	3	100	2	32678161
Pubmed	Trinucleotide repeat containing 6a (Tnrc6a)-mediated microRNA function is required for development of yolk sac endoderm.	TNRC6B TNRC6C TNRC6A	3.41e-05	22	100	3	22187428
Pubmed	Trinucleotide repeat containing 6c (TNRC6c) is essential for microvascular maturation during distal airspace sacculation in the developing lung.	TNRC6B TNRC6C TNRC6A	3.92e-05	23	100	3	28811219
Pubmed	Glycosaminoglycan-binding properties and aggrecanase activities of truncated ADAMTSs: comparative analyses with ADAMTS-5, -9, -16 and -18.	ADAMTS16 ADAMTS18	4.89e-05	4	100	2	16507336
Pubmed	The interactions of GW182 proteins with PABP and deadenylases are required for both translational repression and degradation of miRNA targets.	TNRC6C TNRC6A	4.89e-05	4	100	2	23172285
Pubmed	Cloning and characterization of a family of proteins associated with Mpl.	MPL EPOR	4.89e-05	4	100	2	11784712
Pubmed	DUX4c is up-regulated in FSHD. It induces the MYF5 protein and human myoblast proliferation.	DUX4L9 DUX4	4.89e-05	4	100	2	19829708
Pubmed	Differential gene expression of beta-1,4-galactosyltransferases I, II and V during mouse brain development.	B4GALT5 B4GALT1	4.89e-05	4	100	2	11145975
Pubmed	Robust hematopoietic progenitor cell commitment in the presence of a conflicting cue.	MPL EPOR	4.89e-05	4	100	2	26159733
Pubmed	Structural basis of binding of P-body-associated proteins GW182 and ataxin-2 by the Mlle domain of poly(A)-binding protein.	TNRC6C TNRC6A	4.89e-05	4	100	2	20181956
Pubmed	Monocyte Chemotactic Protein-induced Protein 1 and 4 Form a Complex but Act Independently in Regulation of Interleukin-6 mRNA Degradation.	ZC3H12D TNRC6A	4.89e-05	4	100	2	26134560
Pubmed	O-fucosylation of thrombospondin type 1 repeats restricts epithelial to mesenchymal transition (EMT) and maintains epiblast pluripotency during mouse gastrulation.	ADAMTS7 ADAMTS16 ADAMTS18 POFUT2	6.69e-05	75	100	4	20637190
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	TEAD2 CUL9 DGKQ TNRC6C ZZEF1 BAHD1 KIFC2 MEGF8 ADAMTS7 MTHFR HELZ2 OGDHL	8.01e-05	1105	100	12	35748872
Pubmed	Genetic study of pancreatic proteinase and alpha-amylase in mice (Mus musculus).	CTRB2 CTRB1	8.14e-05	5	100	2	4461036
Pubmed	Chromosomal assignments of genes for trypsin, chymotrypsin B, and elastase in mouse.	CTRB2 CTRB1	8.14e-05	5	100	2	6589791
Pubmed	RNA transcripts, miRNA-sized fragments and proteins produced from D4Z4 units: new candidates for the pathophysiology of facioscapulohumeral dystrophy.	DUX4L2 DUX4	8.14e-05	5	100	2	19359275
Pubmed	Ago-TNRC6 triggers microRNA-mediated decay by promoting two deadenylation steps.	TNRC6B TNRC6C	8.14e-05	5	100	2	19838187
Pubmed	Maea expressed by macrophages, but not erythroblasts, maintains postnatal murine bone marrow erythroblastic islands.	EPOR SIGLEC1	8.14e-05	5	100	2	30674470
Pubmed	Genetic and biochemical characterization of a new chymotrypsin isozyme of the house mouse, CTRA-1.	CTRB2 CTRB1	8.14e-05	5	100	2	1820020
Pubmed	Autoactivation of mouse trypsinogens is regulated by chymotrypsin C via cleavage of the autolysis loop.	CTRB2 CTRB1	1.22e-04	6	100	2	23814066
Pubmed	Sequence variants in SLC16A11 are a common risk factor for type 2 diabetes in Mexico.	SLC16A1 SLC16A11	1.22e-04	6	100	2	24390345
Pubmed	Structural basis for interaction between the conserved cell polarity proteins Inscuteable and Leu-Gly-Asn repeat-enriched protein (LGN).	FRMPD1 INSC	1.22e-04	6	100	2	22074847
Pubmed	Characterization of an exchangeable gene trap using pU-17 carrying a stop codon-beta geo cassette.	TNRC6B ZNF205 B4GALT5 VPS13D TNRC6A WDR73 DCTPP1 POFUT2	1.63e-04	536	100	8	15840001
Pubmed	Exchangeable gene trap using the Cre/mutated lox system.	TNRC6B ZNF205 B4GALT5 VPS13D TNRC6A WDR73 DCTPP1 POFUT2	1.67e-04	538	100	8	10512203
Pubmed	Role of oligosaccharides in the processing and maturation of envelope glycoproteins of human immunodeficiency virus type 1.	MANBA B4GALT6 B4GALT1	1.67e-04	37	100	3	2541446
Pubmed	Biosynthesis and processing of human immunodeficiency virus type 1 envelope glycoproteins: effects of monensin on glycosylation and transport.	MANBA B4GALT6 B4GALT1	1.67e-04	37	100	3	2542563
Pubmed	Cloning, expression analysis, and structural characterization of seven novel human ADAMTSs, a family of metalloproteinases with disintegrin and thrombospondin-1 domains.	ADAMTS16 ADAMTS18	1.70e-04	7	100	2	11867212
Pubmed	Evidence that mannosyl residues are involved in human immunodeficiency virus type 1 (HIV-1) pathogenesis.	MANBA B4GALT6 B4GALT1	1.81e-04	38	100	3	2829950
Pubmed	Characterization of the secreted, native gp120 and gp160 of the human immunodeficiency virus type 1.	MANBA B4GALT6 B4GALT1	1.81e-04	38	100	3	2187500
Pubmed	Prediction of the coding sequences of unidentified human genes. XIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.	FRMPD1 CPEB3 BAHD1 POFUT2	2.20e-04	102	100	4	10231032
Pubmed	A DDX6-CNOT1 complex and W-binding pockets in CNOT9 reveal direct links between miRNA target recognition and silencing.	TNRC6C TNRC6A	2.27e-04	8	100	2	24768540
Pubmed	Genetic predictors of risk and resilience in psychiatric disorders: a cross-disorder genome-wide association study of functional impairment in major depressive disorder, bipolar disorder, and schizophrenia.	ZZEF1 ADAMTS16	2.27e-04	8	100	2	24039173
Pubmed	MicroRNA and target gene expression based clustering of oral cancer, precancer and normal tissues.	CPEB3 ADAMTS7	2.91e-04	9	100	2	27515006
Pubmed	Nine new human Rhodopsin family G-protein coupled receptors: identification, sequence characterisation and evolutionary relationship.	GPR162 GPR139	2.91e-04	9	100	2	15777626
Pubmed	Glycosylation and processing of the human immunodeficiency virus type 1 envelope protein.	MANBA B4GALT6 B4GALT1	3.20e-04	46	100	3	2649653
Pubmed	HIV-1 gp120 N-linked glycosylation differs between plasma and leukocyte compartments.	MANBA B4GALT1	3.63e-04	10	100	2	18215327
Pubmed	Glycosylation site-specific analysis of HIV envelope proteins (JR-FL and CON-S) reveals major differences in glycosylation site occupancy, glycoform profiles, and antigenic epitopes' accessibility.	MANBA B4GALT1	3.63e-04	10	100	2	18330979
Pubmed	Env length and N-linked glycosylation following transmission of human immunodeficiency virus Type 1 subtype B viruses.	MANBA B4GALT1	3.63e-04	10	100	2	18314154
Pubmed	miRNA-mediated deadenylation is orchestrated by GW182 through two conserved motifs that interact with CCR4-NOT.	TNRC6C TNRC6A	3.63e-04	10	100	2	21984185
Pubmed	DUX is a non-essential synchronizer of zygotic genome activation.	DUX4L9 DUX4L2 DUX4L4	4.10e-04	50	100	3	31806660
Pubmed	miRNA repression involves GW182-mediated recruitment of CCR4-NOT through conserved W-containing motifs.	TNRC6C TNRC6A	4.43e-04	11	100	2	21984184
Pubmed	Thrombopoietin rescues in vitro erythroid colony formation from mouse embryos lacking the erythropoietin receptor.	MPL EPOR	4.43e-04	11	100	2	8799165
Pubmed	Insights on ADAMTS proteases and ADAMTS-like proteins from mammalian genetics.	ADAMTS7 ADAMTS18	5.30e-04	12	100	2	25770910
Pubmed	Characterization of a novel gene, sperm-tail-associated protein (Stap), in mouse post-meiotic testicular germ cells.	CTRB2 CTRB1	6.25e-04	13	100	2	11468771
Pubmed	Szt2, a novel gene for seizure threshold in mice.	MPL CDC20	6.25e-04	13	100	2	19624305
Pubmed	Morphogenesis of the kidney and lung requires branch-tip directed activity of the Adamts18 metalloprotease.	ADAMTS16 ADAMTS18	7.28e-04	14	100	2	31242448
Pubmed	The SLC16 gene family-from monocarboxylate transporters (MCTs) to aromatic amino acid transporters and beyond.	SLC16A1 SLC16A11	7.28e-04	14	100	2	12739169
Pubmed	The species-specific differences in the cAMP regulation of the tissue-type plasminogen activator gene between rat, mouse and human is caused by a one-nucleotide substitution in the cAMP-responsive element of the promoters.	ADAMTS16 ADAMTS18	8.39e-04	15	100	2	7543410
Pubmed	Reduced expression of the Kinesin-Associated Protein 3 (KIFAP3) gene increases survival in sporadic amyotrophic lateral sclerosis.	B4GALT6 ZNF746	9.57e-04	16	100	2	19451621
Pubmed	ADAMTS18 Deficiency Affects Neuronal Morphogenesis and Reduces the Levels of Depression-like Behaviors in Mice.	ADAMTS16 ADAMTS18	9.57e-04	16	100	2	30579834
Pubmed	The Eyes Absent family members EYA4 and EYA1 promote PLK1 activation and successful mitosis through tyrosine dephosphorylation.	TNRC6B TNRC6C TNRC6A CDC20	9.93e-04	152	100	4	38360978
Pubmed	A growth factor attenuates HIV-1 Tat and morphine induced damage to human neurons: implication in HIV/AIDS-drug abuse cases.	NOX5 OPRK1	1.08e-03	17	100	2	21483469
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	FRMPD1 TNRC6B CUL9 TNRC6C IGDCC4 MEGF8	1.17e-03	407	100	6	12693553
Pubmed	Autism-like phenotype and risk gene mRNA deadenylation by CPEB4 mis-splicing.	CPEB3 TNRC6B	1.22e-03	18	100	2	30111840
Pubmed	Genome-wide association study identifies multiple susceptibility loci for pancreatic cancer.	CTRB2 RHBDD3 CTRB1	1.24e-03	73	100	3	25086665
Cytoband	Ensembl 112 genes in cytogenetic band chr4q35	DUX4L9 DUX4L2 DUX4 WWC2 DUX4L5 DUX4L6 DUX4L3 DUX4L4 DUX4L7	5.19e-12	117	100	9	chr4q35
Cytoband	4q35.2	DUX4L2 DUX4L5 DUX4L6 DUX4L3 DUX4L4 DUX4L7	2.62e-11	27	100	6	4q35.2
Cytoband	17p13.2	NUP88 ZZEF1 VMO1	2.42e-04	55	100	3	17p13.2
Cytoband	7q32.1	GARIN1A KCP	2.10e-03	31	100	2	7q32.1
Cytoband	Ensembl 112 genes in cytogenetic band chr16q23	CTRB2 ADAMTS18 CTRB1	2.13e-03	116	100	3	chr16q23
Cytoband	16q23.1	CTRB2 CTRB1	2.23e-03	32	100	2	16q23.1
Cytoband	16p12.3	SMG1 GPR139	2.52e-03	34	100	2	16p12.3
GeneFamily	PRD class homeoboxes and pseudogenes	DUX4L9 DUX4L2 DUX4L5 DUX4L6 DUX4L3 DUX4L4 DUX4L7	3.44e-08	92	64	7	521
GeneFamily	Beta 4-glycosyltransferases	B4GALT6 B4GALT5 B4GALT1	2.78e-05	17	64	3	425
GeneFamily	ADAM metallopeptidases with thrombospondin type 1 motif	ADAMTS7 ADAMTS16 ADAMTS18	3.94e-05	19	64	3	50
GeneFamily	Ataxins\|Trinucleotide repeat containing	TNRC6B TNRC6C TNRC6A	9.20e-05	25	64	3	775
Coexpression	IBRAHIM_NRF2_DOWN	MANBA SLC2A8 MAMDC4 KIFC2 PIGQ OGDHL CDC20	3.10e-06	168	97	7	M42513
Coexpression	GSE3982_NKCELL_VS_TH2_UP	MANBA ZZEF1 B4GALT6 ZBP1 PRODH2 TPP1 INAVA	8.84e-06	197	97	7	M5596
ToppCell	Hippocampus-Endothelial-ENDOTHELIAL_TIP-Dcn_1-Dcn_1_2-Endothelial_Tip.Dcn.Rbp4_(Rbp4)\|Hippocampus / BrainAtlas - Mouse McCarroll V32	WNT6 VMO1 ARSI ZBP1 ADAMTS7	2.78e-06	105	93	5	cec0bdfe2bbd87c7e84671c1eeafad17aec1cdb2
ToppCell	Hippocampus-Endothelial-ENDOTHELIAL_TIP-Dcn_1-Dcn_1_2-Endothelial_Tip.Dcn.Rbp4_(Rbp4)-\|Hippocampus / BrainAtlas - Mouse McCarroll V32	WNT6 VMO1 ARSI ZBP1 ADAMTS7	2.78e-06	105	93	5	c4b3f085c7e372e529d2c5d275faba403e830d48
ToppCell	Hippocampus-Endothelial-ENDOTHELIAL_TIP-Dcn_1-Dcn_1_2\|Hippocampus / BrainAtlas - Mouse McCarroll V32	WNT6 VMO1 ARSI ZBP1 ADAMTS7	2.78e-06	105	93	5	dc5f6d62945a699734a71b8ab1d4266db6fb2918
ToppCell	droplet-Kidney-nan-21m-Epithelial-Epcam____proximal_tube_epithelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CMBL AUH PRSS12 HID1 INSC	3.19e-06	108	93	5	7ef144b8039889c8e883b958c50c121bce972e0d
ToppCell	LPS-IL1RA+antiTNF-Myeloid-Dendritic_cells-Monocytes-Macrophages\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	VMO1 MAMDC4 FGL2 ZBP1 TPP1	1.39e-05	146	93	5	b76110b159acd27a2c8d6a9f98336608ace1ec12
ToppCell	5'-Parenchyma_lung-Immune_Lymphocytic-Lymphocytic_T/NK-CD8-positive,_alpha-beta_T_cell-CD8_T_cells-CD8_T_cells_L.1.1.2.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ZFYVE28 ZBP1 SLC16A1 ZBTB3 PSD4	2.43e-05	164	93	5	30c3c25b05a403a509b2e755c2f0878fecb10a02
ToppCell	10x5'-blood-Lymphocytic_Invariant-Inducer-like-ILC3\|blood / Manually curated celltypes from each tissue	PRSS12 FRMPD1 CPEB3 ADAMTS18 SCIN	2.50e-05	165	93	5	f012a27ece54c0f7b73a2f4f89c6ee8b865f8782
ToppCell	390C-Myeloid-Macrophage-SPP1+_Macrophage_4\|Myeloid / Donor, Lineage, Cell class and subclass (all cells)	FRMPD1 ZNF205 ZBP1 SLC22A18AS SIGLEC1	2.97e-05	171	93	5	7c8304573b892ef9ea4e048cba9ea9fbab848dcd
ToppCell	facs-Marrow-T_cells-18m-Hematologic\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CPEB3 HID1 FGL2 ZFYVE28 ZBP1	3.14e-05	173	93	5	e0cf99ddbe6e9eab05d7bf89e9aa124850c6a807
ToppCell	facs-Marrow-T_cells-18m-Hematologic-Unknown_Progenitor\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CPEB3 HID1 FGL2 ZFYVE28 ZBP1	3.22e-05	174	93	5	3b1ee39e85e5f0d6b17fb3051dbfae66cb2be6ee
ToppCell	facs-Marrow-T_cells-18m-Hematologic-hematopoietic_stem_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CPEB3 HID1 FGL2 ZFYVE28 ZBP1	3.31e-05	175	93	5	4be01bf30331162f1998216fb2871a4e626dc440
ToppCell	368C-Myeloid-Macrophage-SPP1+_Macrophage_3\|Myeloid / Donor, Lineage, Cell class and subclass (all cells)	KCP TBX19 PRODH2 SCIN PSD4	3.59e-05	178	93	5	9d575902d3dbe33437c9d4200df093a741269803
ToppCell	368C-Myeloid-Macrophage-SPP1+_Macrophage_3\|368C / Donor, Lineage, Cell class and subclass (all cells)	KCP TBX19 PRODH2 SCIN PSD4	3.59e-05	178	93	5	536a601abcc60867949ea06e9aafb6c7b799b56b
ToppCell	343B-Fibroblasts-Fibroblast-E-\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	EPOR GDF6 ETV2 KCP IGDCC4	4.32e-05	185	93	5	1b8e3ddb91797f84e4b15d2457b0c008e5be50db
ToppCell	343B-Fibroblasts-Fibroblast-E\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	EPOR GDF6 ETV2 KCP IGDCC4	4.32e-05	185	93	5	02cbf492bc40abebaa93a3a208888afae72fbe06
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Principal_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	FGL2 PIGQ ADAMTS16 SCIN MPPED2	4.54e-05	187	93	5	b7689e7f6511920cd2beff27389555fddf685f61
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Cortical_Collecting_Duct_Principal_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	EPOR FGL2 PIGQ SCIN MPPED2	4.90e-05	190	93	5	078f4be52fa4cc8dd9c8d7a2b6d9631c3d902285
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	PIGQ ADAMTS16 OGDHL SCIN MPPED2	5.54e-05	195	93	5	3f517c6fc372bdcaf45b3af373414f13cbebd4ba
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	PIGQ ADAMTS16 OGDHL SCIN MPPED2	5.54e-05	195	93	5	e94bac6a5c788ee160d7feaf2a3c512a3691f995
ToppCell	3'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-club_cell-Club_(nasal)-Club_(nasal)_L.0.2.1.2\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	VMO1 B4GALT5 SLC22A18AS INAVA CDC20	5.96e-05	198	93	5	58f5b5e756ab4aa7234aa8d95fba564d6e8c22d9
ToppCell	BAL-Severe-cDC_1\|Severe / Compartment, Disease Groups and Clusters	FGL2 ZBP1 HELZ2 SIGLEC1 SCIN	6.10e-05	199	93	5	9f5750212b887f92761ade33fc6e108cd5275297
ToppCell	BAL-Mild-cDC_1\|Mild / Compartment, Disease Groups and Clusters	FGL2 ZBP1 HELZ2 SIGLEC1 SCIN	6.10e-05	199	93	5	c55181bdec8952b54198f0d4c9c5c84265b16572
ToppCell	Bronchus_Control_(B.)-Epithelial-TX-Transitional_AT2\|Bronchus_Control_(B.) / Sample group, Lineage and Cell type	TEAD2 FAM114A1 B4GALT6 OGDHL SCIN	6.10e-05	199	93	5	cd581d7330b471431ef427f8a4f5be553f70e068
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	PIGQ ADAMTS16 OGDHL SCIN MPPED2	6.10e-05	199	93	5	3cd6383c50ce342fe5c175e2e50784d634a90e80
Drug	AAPCK	CTRB2 TPP1 CTRB1	2.76e-06	7	99	3	CID000128055
Drug	BOCPheONP	CTRB2 CTRB1	1.87e-05	2	99	2	CID000111308
Drug	MPM-06	CTRB2 CTRB1	1.87e-05	2	99	2	CID000161546
Drug	NSC-374899	CTRB2 CTRB1	1.87e-05	2	99	2	CID000435726
Drug	methylbenzenebutanoate	CTRB2 CTRB1	1.87e-05	2	99	2	CID000281254
Drug	Asp-Arg-Val-Tyr-Val-His-Pro-Phe-His-Leu	CTRB2 CTRB1	1.87e-05	2	99	2	CID004418081
Drug	c189	CTRB2 CTRB1	1.87e-05	2	99	2	CID000248048
Drug	dansyl-D-arginine methyl ester	CTRB2 CTRB1	1.87e-05	2	99	2	CID000191369
Drug	methyl 6-phenylhexanoate	CTRB2 CTRB1	1.87e-05	2	99	2	CID011820300
Drug	5-aminotetrazole	CTRB2 CTRB1	1.87e-05	2	99	2	CID000020467
Drug	2-bromoisobutyric acid	CTRB2 CTRB1	1.87e-05	2	99	2	CID000074924
Drug	p-toluamidine	CTRB2 CTRB1	1.87e-05	2	99	2	CID000122753
Drug	N-acetyl-alpha-azaphenylalanine phenyl ester	CTRB2 CTRB1	1.87e-05	2	99	2	CID000191275
Drug	isobutyl sulfide	CTRB2 CTRB1	1.87e-05	2	99	2	CID000011607
Drug	ICI182,780; Down 200; 1uM; MCF7; HT_HG-U133A	EPOR ZNF205 B4GALT6 B4GALT1 VPS13D MEGF8 MPPED2	2.25e-05	194	99	7	7534_DN
Drug	prazosin hydrochloride; Up 200; 10uM; MCF7; HT_HG-U133A_EA	EPOR SLC2A8 FRMPD1 ZZEF1 TBX19 MTHFR RHBDD3	2.48e-05	197	99	7	826_UP
Drug	zLYCK	NOX5 CTRB2 CTRB1	4.29e-05	16	99	3	CID000171556
Drug	N-acetylbenzotriazole	CTRB2 CTRB1	5.60e-05	3	99	2	CID000087784
Drug	photophor	CTRB2 CTRB1	5.60e-05	3	99	2	CID000014780
Drug	dibutyl iodomethaneboronate	CTRB2 CTRB1	5.60e-05	3	99	2	CID000098591
Drug	zinc;dipicolinate	CTRB2 CTRB1	5.60e-05	3	99	2	CID004309911
Drug	2-oxobut-3-ynoate	CTRB2 CTRB1	5.60e-05	3	99	2	CID000171547
Drug	AFMeq	CTRB2 CTRB1	5.60e-05	3	99	2	CID000194069
Drug	Bz-Cti-otbu	CTRB2 CTRB1	5.60e-05	3	99	2	CID006452691
Drug	n-(2-oxoethyl)benzamide	CTRB2 CTRB1	5.60e-05	3	99	2	CID000188995
Drug	AC1L49DM	CTRB2 CTRB1	5.60e-05	3	99	2	CID000152933
Drug	c140	CTRB2 CTRB1	5.60e-05	3	99	2	CID002783250
Drug	Benzamidomethaneboronic acid	CTRB2 CTRB1	5.60e-05	3	99	2	CID000127677
Drug	phenyl hippurate	CTRB2 CTRB1	5.60e-05	3	99	2	CID000076323
Drug	FK-386	CTRB2 CTRB1	5.60e-05	3	99	2	CID000135044
Drug	FK-375	CTRB2 CTRB1	5.60e-05	3	99	2	CID000135042
Drug	carbostyril-124	CTRB2 CTRB1	5.60e-05	3	99	2	CID000088277
Drug	N-trifluoroacetyl-4-fluorophenylalanine	CTRB2 CTRB1	5.60e-05	3	99	2	CID000328214
Drug	C18 4	CTRB2 CTRB1	5.60e-05	3	99	2	CID000077248
Drug	taraxastane	CTRB2 CTRB1	5.60e-05	3	99	2	CID006429404
Drug	Phe-phe-ome	CTRB2 CTRB1	5.60e-05	3	99	2	CID000151728
Drug	phenylethaneboronic acid	CTRB2 CTRB1	5.60e-05	3	99	2	CID000065389
Drug	3-amino-2-pyridone	CTRB2 CTRB1	5.60e-05	3	99	2	CID000322353
Drug	ASA-BMPA	CTRB2 CTRB1	5.60e-05	3	99	2	CID003035649
Drug	p-nitrophenyl benzoate	CTRB2 CTRB1	5.60e-05	3	99	2	CID000070396
Drug	Cprg	MANBA FUCA2	5.60e-05	3	99	2	CID009894650
Drug	Z-Phe-OMe	CTRB2 CTRB1	5.60e-05	3	99	2	CID003082435
Drug	3-methylcoumarin	CTRB2 CTRB1	5.60e-05	3	99	2	CID000017130
Drug	2-propyl methylphosphonochloridate	CTRB2 CTRB1	5.60e-05	3	99	2	CID000102124
Drug	FK-316	CTRB2 CTRB1	5.60e-05	3	99	2	CID000133688
Drug	AC1L19T8	CTRB2 CTRB1	5.60e-05	3	99	2	CID000000694
Drug	Marinostatin D	CTRB2 CTRB1	5.60e-05	3	99	2	CID000132206
Drug	1FD7	CTRB2 CTRB1	5.60e-05	3	99	2	CID000445579
Drug	Glt-leu-phe-nh-meq	CTRB2 CTRB1	5.60e-05	3	99	2	CID000194914
Drug	AC1L4Z4F	CTRB2 CTRB1	5.60e-05	3	99	2	CID000194913
Drug	Glt-Phe-NH-FMeq	CTRB2 CTRB1	5.60e-05	3	99	2	CID000194912
Drug	diacetyl trimer	CTRB2 CTRB1	5.60e-05	3	99	2	CID000193527
Drug	FK-448	CTRB2 CTRB1	5.60e-05	3	99	2	CID006917869
Drug	Ac-Phe-OMe	CTRB2 CTRB1	5.60e-05	3	99	2	CID000097805
Drug	thiobenzyl N-heptafluorobutyrylanthranilate	CTRB2 CTRB1	5.60e-05	3	99	2	CID000133906
Drug	phenylmethyl	EPOR CTRB2 TPP1 CTRB1	8.36e-05	53	99	4	CID000123147
Drug	azido-Q	CTRB2 GPR162 CTRB1	1.00e-04	21	99	3	CID000125727
Drug	3-Cl	CTRB2 SIGLEC1 CTRB1	1.00e-04	21	99	3	CID000012313
Drug	Benzoyl-dl-leucine	CTRB2 CTRB1	1.12e-04	4	99	2	CID000294887
Drug	Acafcek	CTRB2 CTRB1	1.12e-04	4	99	2	CID000197677
Drug	B-1,3-od	CTRB2 CTRB1	1.12e-04	4	99	2	CID011971053
Drug	dehydromerodesmosine	CTRB2 CTRB1	1.12e-04	4	99	2	CID006443540
Drug	alpha-amyrin palmitate	CTRB2 CTRB1	1.12e-04	4	99	2	CID000185477
Drug	poly-THIQ	CTRB2 CTRB1	1.12e-04	4	99	2	CID006453487
Drug	N-(4-carboxycyclohexylmethyl)-maleimide	CTRB2 CTRB1	1.12e-04	4	99	2	CID011548799
Drug	G2505_sigma	CTRB2 CTRB1	1.12e-04	4	99	2	CID000111098
Drug	p-fluorobenzenesulfonyl chloride	CTRB2 CTRB1	1.12e-04	4	99	2	CID000009588
Drug	1,3,4-trideoxynojirimycin	MANBA FUCA2	1.12e-04	4	99	2	CID000636936
Drug	BSSDA	CTRB2 CTRB1	1.12e-04	4	99	2	CID003081106
Drug	AC1L2HV6	CTRB2 CTRB1	1.12e-04	4	99	2	CID000047328
Drug	AC1L4X1Z	CTRB2 CTRB1	1.12e-04	4	99	2	CID000193815
Drug	NSC-676827	CTRB2 CTRB1	1.12e-04	4	99	2	CID000385555
Drug	6-amino-1,2-benzopyrone	CTRB2 CTRB1	1.12e-04	4	99	2	CID000046152
Drug	nitrophenylethanol	CTRB2 CTRB1	1.12e-04	4	99	2	CID000097851
Drug	H S Q	MANBA CTRB2 B4GALT6 B4GALT5 B4GALT1 PIGQ FUCA2 CTRB1	1.49e-04	351	99	8	CID000000897
Drug	Ac-Trp-OEt	CTRB2 CTRB1	1.86e-04	5	99	2	CID000304749
Drug	apne	CTRB2 CTRB1	1.86e-04	5	99	2	CID000098192
Drug	7-chloro-4-nitrobenzofuran	CTRB2 CTRB1	1.86e-04	5	99	2	CID000130782
Drug	Z-Phe-Leu	CTRB2 CTRB1	1.86e-04	5	99	2	CID000333351
Drug	5'-FSBAzA	CTRB2 CTRB1	1.86e-04	5	99	2	CID000130430
Drug	AC1L3F57	CTRB2 CTRB1	1.86e-04	5	99	2	CID000139565
Drug	3,5-dimethylpyrazole-1-carboxamidine	CTRB2 CTRB1	1.86e-04	5	99	2	CID000097525
Drug	Maap-borov	CTRB2 CTRB1	1.86e-04	5	99	2	CID005486914
Drug	2-amino-4,6-dichlorotriazine	CTRB2 CTRB1	1.86e-04	5	99	2	CID000013615
Drug	AC1O52A0	CTRB2 CTRB1	1.86e-04	5	99	2	CID006475891
Drug	allysine aldol	CTRB2 CTRB1	1.86e-04	5	99	2	CID000191270
Drug	fluphenazine dihydrochloride; Down 200; 10uM; MCF7; HT_HG-U133A	SLC2A8 CUL9 ZNF205 PIGQ SLC22A18AS RHBDD3	1.89e-04	191	99	6	5234_DN
Drug	Selegiline hydrochloride [14611-52-0]; Down 200; 17.8uM; MCF7; HT_HG-U133A	EPOR CUL9 ZNF205 B4GALT6 B4GALT1 PSD4	2.00e-04	193	99	6	4146_DN
Drug	Metergoline [17692-51-2]; Down 200; 10uM; PC3; HT_HG-U133A	FRMPD1 ZZEF1 B4GALT6 VPS13D RHBDD3 SCIN	2.17e-04	196	99	6	6744_DN
Drug	Verteporfin [129497-78-5]; Up 200; 2.8uM; HL60; HT_HG-U133A	FAM114A1 FRMPD1 ZNF205 ST7L PRODH2 SCIN	2.17e-04	196	99	6	6133_UP
Drug	Harmaline hydrochloride dihydrate [6027-98-1]; Down 200; 14uM; MCF7; HT_HG-U133A	EPOR TNRC6B BAHD1 PIGQ TPP1 RHBDD3	2.23e-04	197	99	6	4968_DN
Drug	Enoxacin [74011-58-8]; Down 200; 12.4uM; MCF7; HT_HG-U133A	EPOR PIGQ TBX19 WWC2 TPP1 RHBDD3	2.23e-04	197	99	6	5616_DN
Drug	Monocrotaline [315-22-0]; Up 200; 12.2uM; MCF7; HT_HG-U133A	EPOR ST7L PIGQ SLC22A18AS VPS13D PSD4	2.23e-04	197	99	6	2749_UP
Drug	2-propylpentanoic acid; Down 200; 50uM; MCF7; HT_HG-U133A	SLC2A8 ZNF205 B4GALT1 TBX19 VPS13D RHBDD3	2.30e-04	198	99	6	5219_DN
Drug	sodium 4-phenylbutyrate; Down 200; 1000uM; MCF7; HG-U133A	SLC2A8 CUL9 ZZEF1 PRODH2 VPS13D TPP1	2.30e-04	198	99	6	407_DN
Drug	Prilocaine hydrochloride [1786-81-8]; Down 200; 15.6uM; HL60; HT_HG-U133A	EPOR MANBA TNRC6B TBX19 WWC2 RHBDD3	2.30e-04	198	99	6	2352_DN
Drug	Metanephrine hydrochloride DL [881-95-8]; Down 200; 17.2uM; MCF7; HT_HG-U133A	MANBA AUH TNRC6B CUL9 BAHD1 SLC16A1	2.30e-04	198	99	6	5334_DN
Drug	Sulfamethizole [144-82-1]; Up 200; 14.8uM; HL60; HT_HG-U133A	B4GALT1 PIGQ SLC22A18AS MTHFR RHBDD3 SCIN	2.30e-04	198	99	6	2536_UP
Drug	(1)-Nipecotic acid [498-95-3]; Up 200; 31uM; HL60; HT_HG-U133A	SLC2A8 FRMPD1 ZNF205 ST7L PIGQ SLC22A18AS	2.36e-04	199	99	6	3121_UP
Drug	Finasteride [98319-26-7]; Down 200; 10.8uM; MCF7; HT_HG-U133A	EPOR ZNF205 ZZEF1 TBX19 VPS13D RHBDD3	2.36e-04	199	99	6	6062_DN
Disease	level of chymotrypsinogen B2 in blood serum	CTRB2 CTRB1	9.41e-06	2	91	2	OBA_2041192
Disease	chymotrypsinogen B measurement	CTRB2 CTRB1	2.82e-05	3	91	2	EFO_0801477
Disease	Sclerocystic Ovaries	TEAD2 TNRC6B ZNF205 ADAMTS7 DUX4L5	8.57e-05	144	91	5	C1136382
Disease	Polycystic Ovary Syndrome	TEAD2 TNRC6B ZNF205 ADAMTS7 DUX4L5	8.57e-05	144	91	5	C0032460
Disease	functional impairment measurement	ZZEF1 ADAMTS16	1.96e-04	7	91	2	EFO_0005412
Disease	asparaginase-induced acute pancreatitis	ADAMTS18 CDC20	3.34e-04	9	91	2	EFO_1001507
Disease	trypsin-2 measurement	CTRB2 CTRB1	5.08e-04	11	91	2	EFO_0008305
Disease	cortical thickness	PRSS12 GDF6 TNRC6B CUL9 VPS13D ADAMTS7 MTHFR TNRC6A ADAMTS18 LNX1 MPPED2	6.28e-04	1113	91	11	EFO_0004840
Disease	Modic type vertebral endplate changes	OPRK1 SCIN	7.18e-04	13	91	2	HP_0030775
Disease	anemia (is_implicated_in)	EPOR MTHFR	8.36e-04	14	91	2	DOID:2355 (is_implicated_in)
Disease	cleft lip (is_implicated_in)	GDF6 MTHFR	9.62e-04	15	91	2	DOID:9296 (is_implicated_in)

Protein segments in the cluster

Peptide	Gene	Start	Entry
TEPQSSEGLAWGPWA	nan	161	Q6ZR03
QSTGPWGPGWQELAV	MAMDC4	171	Q6UXC1
NGEDAVPGSWPWQVS	CTRB2	36	Q6GPI1
GNWPWTSPKDGGLGD	EPC1	421	Q9H2F5
NGFPNNYWGWGGEDD	B4GALT1	301	P15291
NLVNVWPSAPGEGGW	CDC20	331	Q12834
AHPDFNGGAWGPWAS	ARSI	511	Q5FYB1
GWGRGPQVAGAAWEP	DUX4L4	311	P0CJ87
FINIPSWGSGADLWG	DGKQ	816	P52824
CAEGAWWFSPDGPAG	SLC22A18AS	106	Q8N1D0
WWFSPDGPAGSAASI	SLC22A18AS	111	Q8N1D0
GWGRGPQVAGAAWEP	DUX4L6	311	P0CJ89
INGFPNAFWGWGGED	B4GALT5	286	O43286
WAAGQASDGSWPGGQ	ARMCX4	1236	Q5H9R4
AGPGTESGAGIWSWD	ARMCX4	1841	Q5H9R4
AAAGPSRGSWFASPW	ADAMTS16	1121	Q8TE57
TGGWSIDWPGEFPFA	ADAMTS18	801	Q8TE60
GFRPEAVDGGWSGWS	ADAMTS7	531	Q9UKP4
WAGSWAGCELPQAGP	IGDCC4	1071	Q8TDY8
NSPGEGGPWVWNTYQ	PRODH2	336	Q9UF12
WAHEDGWPFDGPGGI	MMP26	156	Q9NRE1
SAGTEWGAGAGPHWA	NOX5	116	Q96PH1
WGAGAGPHWASSPLG	NOX5	121	Q96PH1
PESPAGPFGWAGSTW	ZFYVE28	416	Q9HCC9
GPFGWAGSTWADPQE	ZFYVE28	421	Q9HCC9
GAPWTPWFNGWGFNL	MPPED2	176	Q15777
YTPPDGGWGWAVVIG	SLC16A1	11	P53985
WDEFPNGRWGNSSSP	MTHFR	381	P42898
WGCPAGEPWVSVTDF	PRSS12	91	P56730
GPPDGGWGWVVAAAA	SLC16A11	31	Q8NCK7
SGPTWWGPQRLNSGG	NAXE	31	Q8NCW5
GWGRGPQVAGAAWEP	DUX4	311	Q9UBX2
EESARAWGGSWGPGN	GPR162	566	Q16538
GPAIWAQGWVPAAGG	AUH	46	Q13825
SPKAWPEEWGGAGAQ	JPH4	491	Q96JJ6
GWGRGPQVAGAAWEP	DUX4L3	311	P0CJ86
WLDSPWPGFFNVDGE	OGDHL	571	Q9ULD0
GEQISGTVGWWGPAP	MEGF8	651	Q7Z7M0
GWNSNGSWSPGPGER	LNX1	476	Q8TBB1
GWTDWNLALNPEGGP	GBA	416	P04062
WSDGDGGAPDQYWNS	FUCA2	226	Q9BTY2
NGFPNAFWGWGGEDD	B4GALT6	281	Q9UBX8
VGEETGPVGGPHAWW	LINC01599	256	Q8WXQ3
AWSAPSNPWGGLQAG	CPEB3	251	Q8NE35
GGAPPAWGQQGWTEA	FRMPD1	731	Q5SYB0
GWGRGPQVAGAAWEP	DUX4L9	311	Q6RFH8
WQGASSGEAAGPPGW	BAHD1	261	Q8TBE0
GWGRGPQVAGAAWEP	DUX4L7	311	P0CJ90
CSFSWDWGPSFPTQG	MANBA	186	O00462
FWGTWPGVSEAHPGG	FGL2	406	Q14314
ASEGPGGWGLWGVQE	INSC	11	Q1MX18
EPSFGGFWSAWSEPV	EPOR	226	P19235
GTAFPSWDWNPMDGL	CUL9	461	Q8IWT3
FQWKTDGEPGPQGWS	DCTPP1	71	Q9H773
WWSPGSACGLGFVPV	GPR139	16	Q6DWJ6
GWGRGPQVAGAAWEP	DUX4L5	311	P0CJ88
WGAEPDSQALPWSGD	ETV2	76	O00321
SWGGPAGPDCTTSWN	ETV2	181	O00321
WPPRGTQAGAAGNWE	HELZ2	961	Q9BYK8
GLWGPEGWFSSAPCE	EGFEM1P	101	Q0D2K5
SSTPNYGGGWWQSPL	ERVFC1	501	P60507
AQGQAGGARAPWDSW	INAVA	41	Q3KP66
NGEDAVPGSWPWQVS	CTRB1	36	P17538
KWSWGQPGAAGSRAP	KIFC2	756	Q96AC6
LAVDSPPSGGGWAGW	FAM114A1	116	Q8IWE2
GPVGDGELWQTWLPN	NUP88	6	Q99567
SSAWFPGWAEPDSNG	OPRK1	26	P41145
WPQGPFTTWSTPGDA	GARIN1A	101	Q6NXP2
GAPPAGWEVFDVWQG	GDF6	206	Q6KF10
QRSNPAWSAGGGDWA	TNRC6C	586	Q9HCJ0
TAAWGKPPSSGSGWG	TNRC6C	831	Q9HCJ0
WPPASASGQEFWPGQ	POFUT2	16	Q9Y2G5
QGHEPPTFTGWFLGW	SCIN	696	Q9Y6U3
AFGNSWQVSEGLWPG	KCP	1371	Q6ZWJ8
WGSEQGWEDPPIGAE	SLC2A8	226	Q9NY64
DPDWRGFFWSTVPGA	HID1	111	Q8IV36
QVEGWSPWGLPSGSA	PIGQ	681	Q9BRB3
GGGTKYPRSWNDWQP	SMG1	16	Q96Q15
WASLSPEGWQRGGPF	PSD4	391	Q8NDX1
ELQGPGLSWGDFGDW	VMO1	151	Q7Z5L0
FQFWSGGSGPPWNVP	TEAD2	161	Q15562
WGGWSPEGCRTEQPS	ADGRG5	201	Q8IZF4
GQEPWDPSGDWSIFP	CMBL	81	Q96DG6
DWAGASFSPGTPMWA	RHBDD3	276	Q9Y3P4
FTWSGVPEGDGLEWP	ZDHHC6	276	Q9H6R6
GDELPWGWEAGFDPQ	WWC2	56	Q6AWC2
PGDSSTWGTLVDPWG	ZBP1	236	Q9H171
GPAGSPEGSAAWEWG	WNT6	156	Q9Y6F9
GPSEGPGGWPWEQVS	SERPINE3	166	A8MV23
PGGWPWEQVSAAFAQ	SERPINE3	171	A8MV23
GLWCPQPWASSGFEE	ST7L	546	Q8TDW4
FPPESQRGLWGGEGW	MRPL28	71	Q13084
PGPVGNSTFAWFWND	SIGLEC1	1471	Q9BZZ2
NGPTYQGPWSSWSDP	MPL	466	P40238
FPGRSVWAEPAWGDG	ZC3H12D	446	A2A288
ASQEDGAQGAWGWAP	ZNF205	61	O95201
AGGEGWGPHQDWAAV	ZZEF1	16	O43149
AWAAGQPDIGEEPWG	ZNF746	206	Q6NUN9
EGTDEPGSAWAWPGF	TOR3A	31	Q9H497
WTAVASHPFAGWGGP	TBX19	421	O60806
GAGEGPQQAVPWSAW	TMEM239	56	Q8WW34
NKEASSGSGWGEPWG	TNRC6A	1051	Q8NDV7
WCAEVGSWGQGPGPS	WDR73	226	Q6P4I2
AWGEPNESSPGWGEM	TNRC6B	951	Q9UPQ9
DAWGPSRWGQSPGNG	nan	51	Q8N3U1
GWDPVTGWGTPNFPA	TPP1	541	O14773
WFPGWGGWYGQQTPE	VPS13D	436	Q5THJ4
TGGDLFWAPFPSWGT	ZBTB3	36	Q9H5J0
GWGRGPQVAGAAWEP	DUX4L2	311	P0CJ85
SWDAGPGGAPSAWAD	NACAD	71	O15069