Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionoxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen

CYP4A11 CYP27A1 CYP4F2 CYP4A22 CYP4F3 CYP4F11

1.65e-1113956GO:0016713
GeneOntologyMolecularFunctionleukotriene-B4 20-monooxygenase activity

CYP4A11 CYP4F2 CYP4A22 CYP4F3 CYP4F11

4.57e-117955GO:0050051
GeneOntologyMolecularFunctionalkane 1-monooxygenase activity

CYP4A11 CYP4F2 CYP4A22 CYP4F3 CYP4F11

4.57e-117955GO:0018685
GeneOntologyMolecularFunctionarachidonate omega-hydroxylase activity

CYP4A11 CYP4F2 CYP4A22 CYP4F3 CYP4F11

5.42e-1010955GO:0052869
GeneOntologyMolecularFunctionfatty acid omega-hydroxylase activity

CYP4A11 CYP4F2 CYP4A22 CYP4F3 CYP4F11

5.42e-1010955GO:0120250
GeneOntologyMolecularFunctionlong-chain fatty acid omega-hydroxylase activity

CYP4A11 CYP4F2 CYP4A22 CYP4F3 CYP4F11

5.42e-1010955GO:0102033
GeneOntologyMolecularFunctionarachidonate epoxygenase activity

CYP4A11 CYP4F2 CYP4A22 CYP4F3 CYP4F11

8.67e-0824955GO:0008392
GeneOntologyMolecularFunctionarachidonate monooxygenase activity

CYP4A11 CYP4F2 CYP4A22 CYP4F3 CYP4F11

1.63e-0727955GO:0008391
GeneOntologyMolecularFunctionarachidonate binding

CYP4A11 CYP4F2 CYP4A22 CYP4F11

6.30e-0715954GO:0050544
GeneOntologyMolecularFunctionaromatase activity

CYP4A11 CYP4F2 CYP4A22 CYP4F3 CYP4F11

6.35e-0735955GO:0070330
GeneOntologyMolecularFunctionicosanoid binding

CYP4A11 CYP4F2 CYP4A22 CYP4F11

8.37e-0716954GO:0050542
GeneOntologyMolecularFunctionicosatetraenoic acid binding

CYP4A11 CYP4F2 CYP4A22 CYP4F11

8.37e-0716954GO:0050543
GeneOntologyMolecularFunctionalpha-tocopherol omega-hydroxylase activity

CYP4F2 CYP4F3 CYP4F11

1.04e-065953GO:0052871
GeneOntologyMolecularFunctionoxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen

CYP4A11 CYP4F2 CYP4A22 CYP4F3 CYP4F11

3.54e-0649955GO:0016712
GeneOntologyMolecularFunctionheme binding

CYP4A11 CYP27A1 CYP4F2 CYP4A22 DUOX1 CYP4F3 CYP4F11

8.86e-06154957GO:0020037
GeneOntologyMolecularFunctionlong-chain fatty acid binding

CYP4A11 CYP4F2 CYP4A22 CYP4F11

9.02e-0628954GO:0036041
GeneOntologyMolecularFunctiontetrapyrrole binding

CYP4A11 CYP27A1 CYP4F2 CYP4A22 DUOX1 CYP4F3 CYP4F11

1.34e-05164957GO:0046906
GeneOntologyMolecularFunctioniron ion binding

CYP4A11 CYP27A1 RIOX1 CYP4F2 CYP4A22 CYP4F3 CYP4F11

1.45e-05166957GO:0005506
GeneOntologyMolecularFunctionmonooxygenase activity

CYP4A11 CYP27A1 CYP4F2 CYP4A22 CYP4F3 CYP4F11

1.83e-05115956GO:0004497
GeneOntologyMolecularFunction20-hydroxy-leukotriene B4 omega oxidase activity

CYP4F2 CYP4F3

2.24e-052952GO:0097258
GeneOntologyMolecularFunction20-aldehyde-leukotriene B4 20-monooxygenase activity

CYP4F2 CYP4F3

2.24e-052952GO:0097259
GeneOntologyMolecularFunctionmedium-chain fatty acid omega-hydroxylase activity

CYP4A11 CYP4A22

2.24e-052952GO:0140981
GeneOntologyMolecularFunction16-hydroxypalmitate dehydrogenase activity

CYP4A11 CYP4A22

2.24e-052952GO:0103002
GeneOntologyMolecularFunctionoxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen

CYP4A11 CYP27A1 RIOX1 CYP4F2 CYP4A22 CYP4F3 CYP4F11

3.94e-05194957GO:0016705
GeneOntologyMolecularFunctionoxidoreductase activity

CYP4A11 CYP27A1 AOC2 RIOX1 CYP4F2 ACAD10 CYB561A3 CYP4A22 PAOX DUOX1 CYP4F3 CYP4F11 HSDL1

6.75e-057669513GO:0016491
GeneOntologyMolecularFunctionnatural killer cell lectin-like receptor binding

HLA-F ULBP3 MICA

6.76e-0517953GO:0046703
GeneOntologyMolecularFunctionfatty acid binding

CYP4A11 CYP4F2 CYP4A22 CYP4F11

3.28e-0469954GO:0005504
GeneOntologyMolecularFunctiondynein intermediate chain binding

DNHD1 TRIM58 DNAH1

7.21e-0437953GO:0045505
GeneOntologyMolecularFunctionanaphase-promoting complex binding

CDC20B CDC20

7.89e-049952GO:0010997
GeneOntologyMolecularFunctionoxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen

CYP4F2 CYP4F3 CYP4F11

9.07e-0440953GO:0016709
GeneOntologyMolecularFunctionubiquitin ligase activator activity

CDC20B CDC20

9.83e-0410952GO:1990757
GeneOntologyMolecularFunctionbeta-2-microglobulin binding

HLA-F MICA

1.43e-0312952GO:0030881
GeneOntologyMolecularFunctionmonocarboxylic acid binding

CYP4A11 CYP4F2 CYP4A22 CYP4F11

1.71e-03107954GO:0033293
GeneOntologyMolecularFunctioncytoskeletal motor activity

DNHD1 MYO9A KIF26B DNAH1

2.44e-03118954GO:0003774
GeneOntologyMolecularFunctionminus-end-directed microtubule motor activity

DNHD1 DNAH1

3.26e-0318952GO:0008569
GeneOntologyMolecularFunctionubiquitin-protein transferase activator activity

CDC20B CDC20

3.26e-0318952GO:0097027
GeneOntologyMolecularFunctionprotein-lysine N-methyltransferase activity

FAM86B1 FAM86B2 ASH1L

4.18e-0368953GO:0016279
GeneOntologyMolecularFunctionoxidoreductase activity, acting on CH-OH group of donors

CYP4A11 CYP4F2 CYP4A22 CYP4F3

4.28e-03138954GO:0016614
GeneOntologyMolecularFunctionlysine N-methyltransferase activity

FAM86B1 FAM86B2 ASH1L

4.36e-0369953GO:0016278
GeneOntologyMolecularFunctionmicrotubule motor activity

DNHD1 KIF26B DNAH1

4.54e-0370953GO:0003777
GeneOntologyBiologicalProcessleukotriene B4 catabolic process

CYP4A11 CYP4F2 CYP4F3 CYP4F11

6.84e-096974GO:0036101
GeneOntologyBiologicalProcessleukotriene B4 metabolic process

CYP4A11 CYP4F2 CYP4F3 CYP4F11

1.59e-087974GO:0036102
GeneOntologyBiologicalProcessleukotriene catabolic process

CYP4A11 CYP4F2 CYP4F3 CYP4F11

3.17e-088974GO:0036100
GeneOntologyBiologicalProcessorganic hydroxy compound catabolic process

CYP4A11 CYP27A1 CYP4F2 LCT FGF23 CYP4F3 CYP4F11

5.17e-0873977GO:1901616
GeneOntologyBiologicalProcessicosanoid catabolic process

CYP4A11 CYP4F2 CYP4F3 CYP4F11

1.48e-0711974GO:1901523
GeneOntologyBiologicalProcesslong-chain fatty acid catabolic process

CYP4A11 CYP4F2 CYP4F3 CYP4F11

2.21e-0712974GO:0042758
GeneOntologyBiologicalProcessomega-hydroxylase P450 pathway

CYP4A11 CYP4F2 CYP4A22 CYP4F11

4.44e-0714974GO:0097267
GeneOntologyBiologicalProcessarachidonate metabolic process

CYP4A11 CYP4F2 CYP4A22 PLA2G4B CYP4F3 CYP4F11

8.00e-0768976GO:0019369
GeneOntologyBiologicalProcessfatty acid derivative catabolic process

CYP4A11 CYP4F2 CYP4F3 CYP4F11

3.15e-0622974GO:1901569
GeneOntologyBiologicalProcessfat-soluble vitamin catabolic process

CYP4F2 FGF23 CYP4F11

2.15e-0512973GO:0042363
GeneOntologyBiologicalProcessoxylipin metabolic process

CYP4A11 CYP4F11

2.19e-052972GO:0031407
GeneOntologyBiologicalProcessoxylipin biosynthetic process

CYP4A11 CYP4F11

2.19e-052972GO:0031408
GeneOntologyBiologicalProcessolefinic compound metabolic process

CYP4A11 CYP4F2 CYP4A22 PLA2G4B CACNA1H CYP4F3 CYP4F11

2.27e-05180977GO:0120254
GeneOntologyBiologicalProcesslong-chain fatty acid metabolic process

CYP4A11 CYP4F2 CYP4A22 PLA2G4B CYP4F3 CYP4F11

2.64e-05124976GO:0001676
GeneOntologyBiologicalProcessunsaturated fatty acid metabolic process

CYP4A11 CYP4F2 CYP4A22 PLA2G4B CYP4F3 CYP4F11

3.16e-05128976GO:0033559
GeneOntologyBiologicalProcessleukotriene metabolic process

CYP4A11 CYP4F2 CYP4F3 CYP4F11

4.07e-0541974GO:0006691
GeneOntologyBiologicalProcessantigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent

HLA-F ULBP3 MICA

5.40e-0516973GO:0002486
GeneOntologyBiologicalProcessicosanoid metabolic process

CYP4A11 CYP4F2 CYP4A22 PLA2G4B CYP4F3 CYP4F11

5.66e-05142976GO:0006690
GeneOntologyBiologicalProcessantigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway

HLA-F ULBP3 MICA

6.54e-0517973GO:0002484
GeneOntologyBiologicalProcessantigen processing and presentation of endogenous peptide antigen via MHC class Ib

HLA-F ULBP3 MICA

6.54e-0517973GO:0002476
GeneOntologyBiologicalProcessmenaquinone catabolic process

CYP4F2 CYP4F11

6.55e-053972GO:0042361
GeneOntologyBiologicalProcesslauric acid metabolic process

CYP4A11 CYP4A22

6.55e-053972GO:0048252
GeneOntologyBiologicalProcesspositive regulation of anaphase-promoting complex-dependent catabolic process

CDC20B CDC20

6.55e-053972GO:1905786
GeneOntologyBiologicalProcessantigen processing and presentation of peptide antigen via MHC class Ib

HLA-F ULBP3 MICA

7.82e-0518973GO:0002428
GeneOntologyBiologicalProcessvitamin catabolic process

CYP4F2 FGF23 CYP4F11

7.82e-0518973GO:0009111
GeneOntologyBiologicalProcesslipid catabolic process

CYP4A11 CYP27A1 CYP4F2 ACAD10 LCT FGF23 PLA2G4B CYP4F3 CYP4F11

7.94e-05382979GO:0016042
GeneOntologyBiologicalProcessfat-soluble vitamin metabolic process

CYP27A1 CYP4F2 FGF23 CYP4F11

9.69e-0551974GO:0006775
GeneOntologyBiologicalProcessmenaquinone metabolic process

CYP4F2 CYP4F11

1.31e-044972GO:0009233
GeneOntologyBiologicalProcessphylloquinone metabolic process

CYP4F2 CYP4F11

1.31e-044972GO:0042374
GeneOntologyBiologicalProcessphylloquinone catabolic process

CYP4F2 CYP4F11

1.31e-044972GO:0042376
GeneOntologyBiologicalProcessvitamin K catabolic process

CYP4F2 CYP4F11

1.31e-044972GO:0042377
GeneOntologyBiologicalProcessantigen processing and presentation of endogenous peptide antigen via MHC class I

HLA-F ULBP3 MICA

1.67e-0423973GO:0019885
GeneOntologyBiologicalProcessorganic hydroxy compound metabolic process

CYP4A11 CYP27A1 AOC2 CYP4F2 LCT FGF23 DUOX1 CACNA1H CYP4F3 ALG6 CYP4F11

2.12e-046419711GO:1901615
GeneOntologyBiologicalProcessantigen processing and presentation of endogenous peptide antigen

HLA-F ULBP3 MICA

2.15e-0425973GO:0002483
GeneOntologyBiologicalProcessantigen processing and presentation via MHC class Ib

HLA-F ULBP3 MICA

2.15e-0425973GO:0002475
GeneOntologyBiologicalProcessregulation of anaphase-promoting complex-dependent catabolic process

CDC20B CDC20

2.17e-045972GO:1905784
GeneOntologyBiologicalProcessfatty acid catabolic process

CYP4A11 CYP4F2 ACAD10 CYP4F3 CYP4F11

2.20e-04116975GO:0009062
GeneOntologyBiologicalProcessprostaglandin catabolic process

CYP4F2 CYP4F11

3.24e-046972GO:1905344
GeneOntologyBiologicalProcessprostanoid catabolic process

CYP4F2 CYP4F11

3.24e-046972GO:0062232
GeneOntologyBiologicalProcessnegative regulation of ERAD pathway

AQP11 USP14

4.53e-047972GO:1904293
GeneOntologyBiologicalProcessantigen processing and presentation of endogenous antigen

HLA-F ULBP3 MICA

4.53e-0432973GO:0019883
GeneOntologyBiologicalProcessfatty acid derivative metabolic process

CYP4A11 CYP4F2 CYP4F3 CYP4F11

6.07e-0482974GO:1901568
GeneOntologyBiologicalProcessmonocarboxylic acid catabolic process

CYP4A11 CYP4F2 ACAD10 CYP4F3 CYP4F11

6.15e-04145975GO:0072329
GeneOntologyBiologicalProcesssmall molecule catabolic process

CYP4A11 CYP27A1 CYP4F2 ACAD10 FGF23 CYP4F3 FUT8 CYP4F11

8.36e-04421978GO:0044282
DomainCyt_P450_E_grp-I

CYP4A11 CYP27A1 CYP4F2 CYP4A22 CYP4F3 CYP4F11

1.16e-0745976IPR002401
DomainCyt_P450_CS

CYP4A11 CYP27A1 CYP4F2 CYP4A22 CYP4F3 CYP4F11

3.16e-0753976IPR017972
DomainCYTOCHROME_P450

CYP4A11 CYP27A1 CYP4F2 CYP4A22 CYP4F3 CYP4F11

4.92e-0757976PS00086
Domain-

CYP4A11 CYP27A1 CYP4F2 CYP4A22 CYP4F3 CYP4F11

5.46e-07589761.10.630.10
Domainp450

CYP4A11 CYP27A1 CYP4F2 CYP4A22 CYP4F3 CYP4F11

5.46e-0758976PF00067
DomainCyt_P450

CYP4A11 CYP27A1 CYP4F2 CYP4A22 CYP4F3 CYP4F11

6.70e-0760976IPR001128
DomainCdc20/Fizzy

CDC20B CDC20

7.98e-053972IPR033010
DomainFAM86

FAM86B1 FAM86B2

1.59e-044972IPR029426
DomainFAM86

FAM86B1 FAM86B2

1.59e-044972PF14904
DomainMHC_I

HLA-F ULBP3 MICA

1.69e-0421973PF00129
DomainMHC_I_a_a1/a2

HLA-F ULBP3 MICA

1.69e-0421973IPR001039
Domain-

HLA-F ULBP3 MICA

2.54e-04249733.30.500.10
DomainMHC_I-like_Ag-recog

HLA-F ULBP3 MICA

2.54e-0424973IPR011161
PathwayREACTOME_EICOSANOIDS

CYP4A11 CYP4F2 CYP4A22 CYP4F3 CYP4F11

2.01e-0912705M27129
PathwayREACTOME_MISCELLANEOUS_SUBSTRATES

CYP4A11 CYP4F2 CYP4A22 CYP4F3 CYP4F11

2.01e-0912705M27128
PathwayREACTOME_EICOSANOIDS

CYP4A11 CYP4F2 CYP4A22 CYP4F3 CYP4F11

2.01e-0912705MM14845
PathwayWP_EICOSANOID_METABOLISM_VIA_CYTOCHROME_P450_MONOOXYGENASES

CYP4A11 CYP4F2 CYP4A22 CYP4F3 CYP4F11

5.05e-0914705MM15842
PathwayREACTOME_FATTY_ACIDS

CYP4A11 CYP4F2 CYP4A22 CYP4F3 CYP4F11

7.54e-0915705M27126
PathwayWP_EICOSANOID_METABOLISM_VIA_CYCLOOXYGENASES_COX

CYP4A11 CYP4F2 CYP4A22 PLA2G4B CYP4F3 CYP4F11

1.20e-0833706MM15918
PathwayREACTOME_MISCELLANEOUS_SUBSTRATES

CYP4A11 CYP4F2 CYP4A22 CYP4F3 CYP4F11

2.13e-0818705MM14843
PathwayREACTOME_FATTY_ACIDS

CYP4A11 CYP4F2 CYP4A22 CYP4F3 CYP4F11

2.13e-0818705MM14841
PathwayREACTOME_PHASE_I_FUNCTIONALIZATION_OF_COMPOUNDS

CYP4A11 CYP27A1 AOC2 CYP4F2 CYP4A22 PAOX CYP4F3 CYP4F11

4.32e-08104708M738
PathwayREACTOME_PHASE_I_FUNCTIONALIZATION_OF_COMPOUNDS

CYP4A11 CYP27A1 AOC2 CYP4F2 CYP4A22 PAOX CYP4F3 CYP4F11

4.66e-08105708MM14842
PathwayREACTOME_SYNTHESIS_OF_LEUKOTRIENES_LT_AND_EOXINS_EX

CYP4A11 CYP4F2 CYP4A22 CYP4F3 CYP4F11

5.00e-0821705M27137
PathwayREACTOME_SYNTHESIS_OF_LEUKOTRIENES_LT_AND_EOXINS_EX

CYP4A11 CYP4F2 CYP4A22 CYP4F3 CYP4F11

1.28e-0725705MM14858
PathwayREACTOME_SYNTHESIS_OF_16_20_HYDROXYEICOSATETRAENOIC_ACIDS_HETE

CYP4A11 CYP4F2 CYP4A22 CYP4F11

1.79e-0711704MM14863
PathwayWP_EICOSANOID_METABOLISM_VIA_LIPOXYGENASES_LOX

CYP4A11 CYP4F2 CYP4A22 CYP4F3 CYP4F11

5.56e-0733705MM15963
PathwayWP_OXIDATION_BY_CYTOCHROME_P450

CYP4A11 CYP27A1 CYP4F2 CYP4A22 CYP4F3 CYP4F11

5.95e-0762706M39653
PathwayREACTOME_CYTOCHROME_P450_ARRANGED_BY_SUBSTRATE_TYPE

CYP4A11 CYP27A1 CYP4F2 CYP4A22 CYP4F3 CYP4F11

7.20e-0764706M5650
PathwayREACTOME_CYTOCHROME_P450_ARRANGED_BY_SUBSTRATE_TYPE

CYP4A11 CYP27A1 CYP4F2 CYP4A22 CYP4F3 CYP4F11

8.66e-0766706MM14839
PathwayWP_EICOSANOID_METABOLISM_VIA_CYTOCHROME_P450_MONOOXYGENASES_PATHWAY

CYP4A11 CYP4F2 CYP4A22

9.64e-069703M39819
PathwayKEGG_ARACHIDONIC_ACID_METABOLISM

CYP4A11 CYP4F2 CYP4A22 PLA2G4B CYP4F3

9.76e-0658705M5410
PathwayREACTOME_ARACHIDONIC_ACID_METABOLISM

CYP4A11 CYP4F2 CYP4A22 CYP4F3 CYP4F11

1.06e-0559705M27140
PathwayREACTOME_BIOLOGICAL_OXIDATIONS

CYP4A11 CYP27A1 AOC2 CYP4F2 CYP4A22 PAOX CYP4F3 CYP4F11

1.23e-05219708MM14838
PathwayREACTOME_ARACHIDONIC_ACID_METABOLISM

CYP4A11 CYP4F2 CYP4A22 CYP4F3 CYP4F11

1.25e-0561705MM14861
PathwayREACTOME_BIOLOGICAL_OXIDATIONS

CYP4A11 CYP27A1 AOC2 CYP4F2 CYP4A22 PAOX CYP4F3 CYP4F11

1.27e-05220708M10320
PathwayWP_EICOSANOID_METABOLISM_VIA_CYCLOOXYGENASES_COX

CYP4A11 CYP4F2 CYP4A22 PLA2G4B

1.59e-0531704M39851
PathwayREACTOME_FATTY_ACID_METABOLISM

CYP4A11 CYP4F2 ACAD10 CYP4A22 CYP4F3 CYP4F11

1.95e-04170706MM15573
PathwayREACTOME_METABOLISM_OF_LIPIDS

CYP4A11 CYP27A1 CYP4F2 ACAD10 CYP4A22 DGAT2L6 CEPT1 PLA2G4B CYP4F3 FITM1 CYP4F11

2.22e-046207011MM15193
PathwayREACTOME_FATTY_ACID_METABOLISM

CYP4A11 CYP4F2 ACAD10 CYP4A22 CYP4F3 CYP4F11

2.35e-04176706M27854
PathwayWP_EICOSANOID_METABOLISM_VIA_LIPOOXYGENASES_LOX

CYP4A11 CYP4F2 CYP4A22

3.91e-0429703M39858
PathwayREACTOME_SYNTHESIS_OF_16_20_HYDROXYEICOSATETRAENOIC_ACIDS_HETE

CYP4A11 CYP4F2

8.56e-049702M27143
PathwayREACTOME_METABOLISM_OF_LIPIDS

CYP4A11 CYP27A1 CYP4F2 ACAD10 CYP4A22 DGAT2L6 CEPT1 PLA2G4B CYP4F3 FITM1 CYP4F11

1.18e-037577011M27451
PathwayREACTOME_HDR_THROUGH_MMEJ_ALT_NHEJ

PARP1 POLQ

1.55e-0312702M27569
PathwayREACTOME_HDR_THROUGH_MMEJ_ALT_NHEJ

PARP1 POLQ

1.55e-0312702MM15282
Pubmed

Human CYP4F3s are the main catalysts in the oxidation of fatty acid epoxides.

CYP4A11 CYP4F2 CYP4F3

2.17e-08398315145985
Pubmed

Increased renal proximal convoluted tubule transport contributes to hypertension in Cyp4a14 knockout mice.

CYP4A11 CYP4A22 SLC9A3

2.17e-08398319713718
Pubmed

Comparison of cytochrome P450 (CYP) genes from the mouse and human genomes, including nomenclature recommendations for genes, pseudogenes and alternative-splice variants.

CYP4A11 CYP27A1 CYP4F2 CYP4A22 CYP4F3 CYP4F11

4.86e-087098615128046
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

ANKS6 LAT2 AOC2 APBB3 IPP RALGAPA2 PIM3 TULP4 FAM83F PLA2G4B CACNA1H TNKS1BP1 TANC1 HERC2 ZNF324B BAHCC1

7.97e-081105981635748872
Pubmed

Omega oxidation of 3-hydroxy fatty acids by the human CYP4F gene subfamily enzyme CYP4F11.

CYP4F2 CYP4F3 CYP4F11

8.66e-08498318065749
Pubmed

Comparative expression profiling of 40 mouse cytochrome P450 genes in embryonic and adult tissues.

CYP4A11 CYP27A1 CYP4F2 CYP4A22 CYP4F11

1.59e-074498512745259
Pubmed

The cytochrome P450 4 (CYP4) family.

CYP4F2 CYP4F3 CYP4F11

4.31e-0769839068972
Pubmed

Cytochrome P450 omega hydroxylase (CYP4) function in fatty acid metabolism and metabolic diseases.

CYP4A11 CYP4F2

7.86e-06298218433732
Pubmed

Cytochrome P450-dependent catabolism of vitamin K: ω-hydroxylation catalyzed by human CYP4F2 and CYP4F11.

CYP4F2 CYP4F11

7.86e-06298224138531
Pubmed

Functional variant of CYP4A11 20-hydroxyeicosatetraenoic acid synthase is associated with essential hypertension.

CYP4A11 CYP4A22

7.86e-06298215611369
Pubmed

Association of common variants of CYP4A11 and CYP4F2 with stroke in the Han Chinese population.

CYP4A11 CYP4F2

7.86e-06298220130494
Pubmed

20-HETE induces remodeling of renal resistance arteries independent of blood pressure elevation in hypertension.

CYP4A11 CYP4A22

7.86e-06298223825080
Pubmed

Salt-sensitive hypertension is associated with dysfunctional Cyp4a10 gene and kidney epithelial sodium channel.

CYP4A11 CYP4A22

7.86e-06298216691295
Pubmed

The P450 gene superfamily: recommended nomenclature.

CYP4A11 CYP4A22

7.86e-0629823829886
Pubmed

Cytochrome 4A11 Genetic Polymorphisms Increase Susceptibility to Ischemic Stroke and Associate with Atherothrombotic Events After Stroke in Chinese.

CYP4A11 CYP4F2

7.86e-06298225734770
Pubmed

Recurrent deletions in clonal hematopoiesis are driven by microhomology-mediated end joining.

PARP1 POLQ

7.86e-06298233911081
Pubmed

Cloning and expression of a novel form of leukotriene B4 omega-hydroxylase from human liver.

CYP4F2 CYP4F3

7.86e-0629828026587
Pubmed

Induction of cytochrome P450 4A14 contributes to angiotensin II-induced renal fibrosis in mice.

CYP4A11 CYP4A22

7.86e-06298229277328
Pubmed

Genetic polymorphism of CYP4A11 and CYP4A22 genes and in silico insights from comparative 3D modelling in a French population.

CYP4A11 CYP4A22

7.86e-06298221820496
Pubmed

A single nucleotide polymorphism in the CYP4F2 but not CYP4A11 gene is associated with increased 20-HETE excretion and blood pressure.

CYP4A11 CYP4F2

7.86e-06298218391101
Pubmed

Androgen-sensitive hypertension associates with upregulated vascular CYP4A12-20-HETE synthase.

CYP4A11 CYP4A22

7.86e-06298223641057
Pubmed

Renal function and vasomotor activity in mice lacking the Cyp4a14 gene.

CYP4A11 CYP4A22

7.86e-06298220943934
Pubmed

The Blood Pressure-Lowering Effect of 20-HETE Blockade in Cyp4a14(-/-) Mice Is Associated with Natriuresis.

CYP4A11 CYP4A22

7.86e-06298228912346
Pubmed

Altered inflammatory responses to Citrobacter rodentium infection, but not bacterial lipopolysaccharide, in mice lacking the Cyp4a10 or Cyp4a14 genes.

CYP4A11 CYP4A22

7.86e-06298224413902
Pubmed

The rat clofibrate-inducible CYP4A subfamily. II. cDNA sequence of IVA3, mapping of the Cyp4a locus to mouse chromosome 4, and coordinate and tissue-specific regulation of the CYP4A genes.

CYP4A11 CYP4A22

7.86e-0629822766933
Pubmed

Deduced amino acid sequence of a murine cytochrome P-450 Cyp4a protein: developmental and hormonal regulation in liver and kidney.

CYP4A11 CYP4A22

7.86e-0629828031839
Pubmed

Role of human CYP4F2 in hepatic catabolism of the proinflammatory agent leukotriene B4.

CYP4A11 CYP4F2

7.86e-0629829799565
Pubmed

Expression and characterization of human cytochrome P450 4F11: Putative role in the metabolism of therapeutic drugs and eicosanoids.

CYP4F3 CYP4F11

7.86e-06298215364545
Pubmed

Human fatty acid omega-hydroxylase, CYP4A11: determination of complete genomic sequence and characterization of purified recombinant protein.

CYP4A11 CYP4A22

7.86e-06298210860550
Pubmed

The V433M variant of the CYP4F2 is associated with ischemic stroke in male Swedes beyond its effect on blood pressure.

CYP4A11 CYP4F2

7.86e-06298218574070
Pubmed

Mouse Cyp4a isoforms: enzymatic properties, gender- and strain-specific expression, and role in renal 20-hydroxyeicosatetraenoic acid formation.

CYP4A11 CYP4A22

7.86e-06298217112342
Pubmed

Alterations in the regulation of androgen-sensitive Cyp 4a monooxygenases cause hypertension.

CYP4A11 CYP4A22

7.86e-06298211320253
Pubmed

A Novel Polymorphism in the Promoter of the CYP4A11 Gene Is Associated with Susceptibility to Coronary Artery Disease.

CYP4A11 CYP4F2

7.86e-06298229484037
Pubmed

Interaction Between CYP4F2 rs2108622 and CPY4A11 rs9333025 Variants Is Significantly Correlated with Susceptibility to Ischemic Stroke and 20-Hydroxyeicosatetraenoic Acid Level.

CYP4A11 CYP4F2

7.86e-06298226959478
Pubmed

Characterization of the CYP4A11 gene, a second CYP4A gene in humans.

CYP4A11 CYP4A22

7.86e-06298212464262
Pubmed

Ubiquitin-Specific Protease 14 (USP14) Aggravates Inflammatory Response and Apoptosis of Lung Epithelial Cells in Pneumonia by Modulating Poly (ADP-Ribose) Polymerase-1 (PARP-1).

USP14 PARP1

7.86e-06298234085162
Pubmed

High-fat diet-induced obesity and insulin resistance in CYP4a14-/- mice is mediated by 20-HETE.

CYP4A11 CYP4A22

7.86e-06298230088983
Pubmed

Expression of cytochrome P450 4A mRNA in mouse lung: effect of clofibrate and interleukin-1beta.

CYP4A11 CYP4A22

7.86e-06298215066132
Pubmed

Mechanisms of podocyte injury in diabetes: role of cytochrome P450 and NADPH oxidases.

CYP4A11 CYP4A22

7.86e-06298219208908
Pubmed

Genetic analysis of resistance to radiation lymphomagenesis with recombinant inbred strains of mice.

CYP4A11 CYP4A22

2.35e-0539822354437
Pubmed

Phosphorylation-dependent degradation of MEF2C contributes to regulate G2/M transition.

MEF2C CDC20

2.35e-05398225789873
Pubmed

Mouse cathepsin D gene: molecular organization, characterization of the promoter, and chromosomal localization.

CYP4A11 CYP4A22

2.35e-0539828011168
Pubmed

Ablation of cytochrome P450 omega-hydroxylase 4A14 gene attenuates hepatic steatosis and fibrosis.

CYP4A11 CYP4A22

2.35e-05398228270609
Pubmed

The P450 superfamily: update on new sequences, gene mapping, and recommended nomenclature.

CYP4A11 CYP4A22

2.35e-0539821991046
Pubmed

Integrated transcript and genome analyses reveal NKX2-1 and MEF2C as potential oncogenes in T cell acute lymphoblastic leukemia.

MEF2C NKX2-2

2.35e-05398221481790
Pubmed

Peroxisome proliferator activated receptor alpha regulates a male-specific cytochrome P450 in mouse liver.

CYP4A11 CYP4A22

2.35e-05398215313227
Pubmed

H19/Mir-130b-3p/Cyp4a14 potentiate the effect of praziquantel on liver in the treatment of Schistosoma japonicum infection.

CYP4A11 CYP4A22

2.35e-05398237659685
Pubmed

Multiple apical plasma membrane constituents are associated with susceptibility to meconium ileus in individuals with cystic fibrosis.

SLC9A3 SLC6A14

2.35e-05398222466613
Pubmed

A novel murine P-450 gene, Cyp4a14, is part of a cluster of Cyp4a and Cyp4b, but not of CYP4F, genes in mouse and humans.

CYP4A11 CYP4A22

2.35e-0539829271096
Pubmed

Disruption of mouse cytochrome p450 4f14 (Cyp4f14 gene) causes severe perturbations in vitamin E metabolism.

CYP4F2 CYP4F11

4.70e-05498222665481
Pubmed

Murine c-mpl: a member of the hematopoietic growth factor receptor superfamily that transduces a proliferative signal.

CYP4A11 CYP4A22

4.70e-0549828334987
Pubmed

Mapping of the azh locus to mouse chromosome 4.

CYP4A11 CYP4A22

4.70e-0549821552159
Pubmed

Varicella-Zoster Virus and Herpes Simplex Virus 1 Differentially Modulate NKG2D Ligand Expression during Productive Infection.

ULBP3 MICA

4.70e-05498225995251
Pubmed

Expression and catalytic activity of mouse leukotriene B4 omega-hydroxylase, CYP4F14.

CYP4F2 CYP4F11

4.70e-05498211185557
Pubmed

Altered expression of hepatic CYP2E1 and CYP4A in obese, diabetic ob/ob mice, and fa/fa Zucker rats.

CYP4A11 CYP4A22

4.70e-05498210049703
Pubmed

Metabolism of arachidonic acid to 20-hydroxy-5,8,11, 14-eicosatetraenoic acid by P450 enzymes in human liver: involvement of CYP4F2 and CYP4A11.

CYP4A11 CYP4F2

4.70e-0549829618440
Pubmed

Differences in metabolite burden of di(2-ethylhexyl)phthalate in pregnant and postpartum dams and their offspring in relation to drug-metabolizing enzymes in mice.

CYP4A11 CYP4A22

4.70e-05498222159897
Pubmed

[Expression of NKG2D ligands on dendritic cells at different development stages and its effect on cytotoxicity of NK cells].

ULBP3 MICA

4.70e-05498218394338
Pubmed

Formation of 20-hydroxyeicosatetraenoic acid, a vasoactive and natriuretic eicosanoid, in human kidney. Role of Cyp4F2 and Cyp4A11.

CYP4A11 CYP4F2

4.70e-05498210660572
Pubmed

Salt modulates vascular response through adenosine A(2A) receptor in eNOS-null mice: role of CYP450 epoxygenase and soluble epoxide hydrolase.

CYP4A11 CYP4A22

4.70e-05498221161333
Pubmed

Disruption of P450-mediated vitamin E hydroxylase activities alters vitamin E status in tocopherol supplemented mice and reveals extra-hepatic vitamin E metabolism.

CYP4F2 CYP4F11

7.82e-05598222969154
Pubmed

Species-specific induction of cytochrome P-450 4A RNAs: PCR cloning of partial guinea-pig, human and mouse CYP4A cDNAs.

CYP4A11 CYP4A22

7.82e-0559828363569
Pubmed

FAM86A methylation of eEF2 links mRNA translation elongation to tumorigenesis.

FAM86B1 FAM86B2

7.82e-05598238508183
Pubmed

Cytochrome P4504f, a potential therapeutic target limiting neuroinflammation.

CYP4F2 CYP4F11

7.82e-05598221466787
Pubmed

UL16-binding proteins, novel MHC class I-related proteins, bind to NKG2D and activate multiple signaling pathways in primary NK cells.

ULBP3 MICA

7.82e-05598211777960
Pubmed

Modulation by salt intake of the vascular response mediated through adenosine A(2A) receptor: role of CYP epoxygenase and soluble epoxide hydrolase.

CYP4A11 CYP4A22

7.82e-05598220427718
Pubmed

Cytochromes P450 from family 4 are the main omega hydroxylating enzymes in humans: CYP4F3B is the prominent player in PUFA metabolism.

CYP4F2 CYP4F3

7.82e-05598218577768
Pubmed

Cell surface organization of stress-inducible proteins ULBP and MICA that stimulate human NK cells and T cells via NKG2D.

ULBP3 MICA

7.82e-05598215051759
Pubmed

Mapping of guanylin to murine chromosome 4 and human chromosome 1p34-p35.

CYP4A11 CYP4A22

7.82e-0559827601480
Pubmed

Identification of signaling pathways that specify a subset of migrating enteric neural crest cells at the wavefront in mouse embryos.

EFNA4 NKX2-2 CDC20

8.33e-053098338636517
Pubmed

Organization of the distal end of mouse chromosome 4.

CYP4A11 CYP4A22

1.17e-0469823166417
Pubmed

Peroxisome proliferator-activated receptor-α accelerates α-chlorofatty acid catabolism.

CYP4A11 CYP4A22

1.17e-04698228007964
Pubmed

CNS macrophages differentially rely on an intronic Csf1r enhancer for their development.

MRC1 CSF1R

1.17e-04698233323375
Pubmed

Interactions of human NKG2D with its ligands MICA, MICB, and homologs of the mouse RAE-1 protein family.

ULBP3 MICA

1.17e-04698211491531
Pubmed

Genetic differences between five European populations.

LCT HERC2

1.17e-04698220616560
Pubmed

Peroxisome proliferator-activated receptor alpha-responsive genes induced in the newborn but not prenatal liver of peroxisomal fatty acyl-CoA oxidase null mice.

CYP4A11 CYP4A22

1.17e-04698211461119
Pubmed

Genesis, a winged helix transcriptional repressor with expression restricted to embryonic stem cells.

CYP4A11 CYP4A22

1.17e-0469828798505
Pubmed

Mouse uroporphyrinogen decarboxylase: cDNA cloning, expression, and mapping.

CYP4A11 CYP4A22

1.17e-0469828661721
Pubmed

TNKS1BP1 functions in DNA double-strand break repair though facilitating DNA-PKcs autophosphorylation dependent on PARP-1.

PARP1 TNKS1BP1

1.17e-04698225749521
Pubmed

Activation of PPAR-alpha in streptozotocin-induced diabetes is essential for resistance against acetaminophen toxicity.

CYP4A11 CYP4A22

1.64e-04798212958197
Pubmed

Perfluorocarboxylic acids induce cytochrome P450 enzymes in mouse liver through activation of PPAR-alpha and CAR transcription factors.

CYP4A11 CYP4A22

1.64e-04798218648086
Pubmed

ULBPs, novel MHC class I-related molecules, bind to CMV glycoprotein UL16 and stimulate NK cytotoxicity through the NKG2D receptor.

ULBP3 MICA

1.64e-04798211239445
Pubmed

Molecular mapping of the mouse db mutation.

CYP4A11 CYP4A22

1.64e-0479821978328
Pubmed

NKG2D ligand overexpression in lupus nephritis correlates with increased NK cell activity and differentiation in kidneys but not in the periphery.

ULBP3 MICA

1.64e-04798225583577
Pubmed

Role of ω-hydroxylase in adenosine-mediated aortic response through MAP kinase using A2A-receptor knockout mice.

CYP4F2 CYP4F11

1.64e-04798222160543
Pubmed

Drug metabolizing enzyme induction pathways in experimental non-alcoholic steatohepatitis.

CYP4A11 CYP4A22

2.18e-04898218488193
Pubmed

Neuroepithelial progenitors generate and propagate non-neuronal action potentials across the spinal cord.

CACNA1H NKX2-2

2.18e-04898234478646
Pubmed

Microdissection and microcloning of mid-chromosome 4: genetic mapping of 41 microdissection clones.

CYP4A11 CYP4A22

2.18e-0489828098006
Pubmed

Cleavage of human cytosolic phospholipase A2 by caspase-1 (ICE) and caspase-8 (FLICE).

PARP1 PLA2G4B

2.18e-0489829875225
Pubmed

Association study between single-nucleotide polymorphisms in 199 drug-related genes and commonly measured quantitative traits of 752 healthy Japanese subjects.

LAT2 CYP4A11 CYP27A1 CYP4F2 CYP4F3

2.23e-0419398519343046
Pubmed

Mapping genes encoding drug-metabolizing enzymes in recombinant inbred mice.

CYP4A11 CYP4A22

2.79e-0499821685137
Pubmed

The P450 superfamily: update on new sequences, gene mapping, accession numbers, early trivial names of enzymes, and nomenclature.

CYP4A11 CYP4A22

2.79e-0499827678494
Pubmed

Pellino1 specifically binds to phospho-Thr18 of p53 and is recruited to sites of DNA damage.

PARP1 HERC2

2.79e-04998230987826
Pubmed

Recognition of the ligand-type specificity of classical and non-classical MHC I proteins.

HLA-F MICA

2.79e-04998222001201
Pubmed

Interactomes of Glycogen Synthase Kinase-3 Isoforms.

MYO9A KIF26B CEP350 TNKS1BP1 TANC1

3.22e-0420998536779422
Pubmed

Differentiation of the mononuclear phagocyte system during mouse embryogenesis: the role of transcription factor PU.1.

MRC1 CSF1R

3.48e-041098210381505
Pubmed

Regulation of lymphangiogenesis in the diaphragm by macrophages and VEGFR-3 signaling.

MRC1 CSF1R

3.48e-041098227464987
Pubmed

Genetic mapping of meander tail, a mouse mutation affecting cerebellar development.

CYP4A11 CYP4A22

3.48e-04109822037292
Pubmed

Endocardially Derived Macrophages Are Essential for Valvular Remodeling.

MRC1 CSF1R

3.48e-041098230799229
Pubmed

A transcript finishing initiative for closing gaps in the human transcriptome.

ZSWIM8 ACAD10

4.25e-041198215197164
Cytoband20p11.22

RALGAPA2 NKX2-2

1.23e-04897220p11.22
GeneFamilyCytochrome P450 family 4

CYP4A11 CYP4F2 CYP4A22 CYP4F3 CYP4F11

2.23e-07366851003
CoexpressionGSE36476_YOUNG_VS_OLD_DONOR_MEMORY_CD4_TCELL_16H_TSST_ACT_UP

CYP4A11 ZDHHC14 DUOX1 CACNA1H MICA CYP4F3 POLQ

7.98e-06196967M5313
CoexpressionVALK_AML_WITH_FLT3_ITD

MRC1 LCT IL1RAP BAHCC1

1.54e-0541964M10010
ToppCellfacs-Marrow-T-cells-3m-Hematologic-MPP_Fraction_B_+_C|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ECT2L ACAD10 FBXO17 EFNA4 POLQ BAHCC1

1.86e-06170966d70aaa0f4e5034bb9f61b832b5f9123870936d3c
ToppCellPND07-28-samps-Myeloid-Macrophage-CD163+_Macrophage|PND07-28-samps / Age Group, Lineage, Cell class and subclass

MRC1 CYP27A1 ZDHHC14 PAOX CSF1R SUSD1

1.99e-061729669a659442dc41bd2a4361a7e38a7ee37a39781667
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

AOC2 ZDHHC14 ULBP3 FGF23 FUT8

8.56e-06128965e100629f6038e32176ffcc81bd06bd175df46cef
ToppCellPND01-03-samps-Myeloid-Macrophage-CD163+_Macrophage|PND01-03-samps / Age Group, Lineage, Cell class and subclass

MRC1 ANKS6 ZDHHC14 PAOX CSF1R

2.52e-051609654480a7d6bd48d06b4e5196faac868f31ab7ed3ad
ToppCellsystemic_lupus_erythematosus-flare-Lymphocytic_B-B_naive-male|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

ECT2L CYB561A3 MEF2C FGF23 PARP1

2.91e-051659658003fd2aa3f5c9d0e99054af4ad2d79a4a3c4829
ToppCellControl-T/NK_proliferative|World / Disease group and Cell class

ARPC1A CYP27A1 DUOX1 TANC1 CDC20

3.27e-05169965fca735cbb55fce4d32dc6632a39acea1d16b87ab
ToppCelldroplet-Marrow-nan-18m-Myeloid-basophil|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CYP27A1 DNAH1 CEP350 CSF1R BAHCC1

3.76e-0517496555cc8300489d11322724159ec7d0e1d32a702e91
ToppCellwk_20-22-Epithelial-Proximal_epithelial-Proximal_secretory_3|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

ANKS6 KIF26B FZD8 FAM83F PGBD5

3.76e-051749659e5fae9ecc7c0111fc8a252e72b89dc89c0d3a7c
ToppCelldroplet-Marrow-nan-24m-Lymphocytic-late_pro-B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TMTC4 C2 CACNA1H FUT8 FAM135A

3.76e-05174965cdfc50e5383c8670ce5109736aff36406f46c03d
ToppCell3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.0.5|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PLEKHH1 FAM83F CYP4F3 TANC1 SLC6A14

4.30e-051799656e965e424eebef50f0202cff75f458be395cfca1
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

MYO9A ZDHHC14 USP43 NLGN1 FBXO17

5.16e-05186965f0c8de4f6ae9047b9108a47a2af8c5f42bc103b0
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

MYO9A ZDHHC14 USP43 NLGN1 FBXO17

5.43e-05188965af740fa78542438fdff627ea1f74f4eee43316be
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

MYO9A ZDHHC14 NLGN1 SUSD1 UBASH3B

5.56e-05189965904b8337e2cabac2f0bf5dad5598fc429581ed81
ToppCellCTRL-Lymphoid-B_cell|Lymphoid / Disease state, Lineage and Cell class

LAT2 ZDHHC14 MEF2C CEPT1 FUT8

5.56e-0518996514f3a8c0f4f057ad4e6839b4c3eeaf956d6dc92e
ToppCellhematopoetic_progenitors-CD34+_CLP|hematopoetic_progenitors / Lineage and Cell class

LAT2 MEF2C PIM3 UBASH3B BAHCC1

5.70e-05190965117abdafd294c85ccb5d8ea907e3c0491b7200b2
ToppCellAdult-Immune-monocyte-D175|Adult / Lineage, Cell type, age group and donor

LAT2 MEF2C CSF1R SUSD1 UBASH3B

5.85e-05191965cbebb4d9550fdcd606cb3685ac9546c6b73fd422
ToppCellControl-Endothelial-Endothelial-Gen_Cap|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ZDHHC14 RALGAPA2 MEF2C UBASH3B FAM135A

6.14e-05193965e1d546165dcc2392f540162206852c4717d7306f
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Immune-Myeloid-Monocytic-Monocyte-derived_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

MRC1 LAT2 MEF2C CSF1R IL1RAP

6.45e-0519596562dc745e1aa3e2e58afa16c7bb2cf9b03d4e8105
ToppCell3'-GW_trimst-1-LargeIntestine-Hematopoietic-Myeloid-LYVE1+_Macrophage|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MRC1 LAT2 MEF2C CSF1R C2

6.45e-05195965c14d730dd5c94247bc09711eaa5a53bd5a5957be
ToppCell3'-GW_trimst-1-SmallIntestine-Hematopoietic-Myeloid-LYVE1+_Macrophage|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MRC1 LAT2 MEF2C CSF1R C2

6.77e-05197965759f26753f76af3ae8d8527c4d221206245a3d45
ToppCelldistal-2-Hematologic-EREG+_Dendritic|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

MRC1 LAT2 CSF1R CYP4F3 IL1RAP

6.77e-051979656fcca7c071e35786b715adeb18be317d34315d7e
ToppCellfrontal_cortex-Non-neuronal-macrophage-Macrophage-PVM_Mrc1|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

MRC1 CYP27A1 CSF1R C2

2.95e-04148964d3ea907f8f408e9bb97ed223a3089e403e35f911
ToppCelldroplet-Heart-HEART_(ALL_4:4:4:1:1)-30m-Hematologic-leukocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MRC1 LAT2 CSF1R PLA2G4B

2.95e-041489647c7c87b57aa16f8b91698489df39ace5a3a53df8
ToppCellPBMC-Severe-cDC_3|Severe / Compartment, Disease Groups and Clusters

MRC1 ZNF835 FZD8 CYP4F3

3.27e-041529641a3f8ed476aa9a39742b4684be2c704669e4a3d0
ToppCellFrontal_cortex-Neuronal-Excitatory-eN1(Slc17a7)-eN1_2-Nptxr-Excitatory_Neuron.Slc17a7.Nptxr-Ndst4_(Superficial_layer_pyramidal_cells--dorsal_endopiriform_nucleus_or_piriform_cortex)|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

IGFN1 DGAT2L6 PLA2G4B

3.41e-04639631f609765ed8b3a09095427da5dab7ba03a763192
ToppCellTCGA-Bone_and_Soft_Tissue-Solid_Tissue_Normal|TCGA-Bone_and_Soft_Tissue / Sample_Type by Project: Shred V9

CYP4A11 CYP4F2 CYP4A22 CYP4F3

3.43e-0415496489a60a79d07466d7ad05888d10a72d3b1ab384af
ToppCellTCGA-Bone_and_Soft_Tissue-Solid_Tissue_Normal-Connective_tissue_normal|TCGA-Bone_and_Soft_Tissue / Sample_Type by Project: Shred V9

CYP4A11 CYP4F2 CYP4A22 CYP4F3

3.43e-04154964f1fea1a87e977221fa125b62287368be9af4987d
ToppCellTCGA-Bone_and_Soft_Tissue-Solid_Tissue_Normal-Connective_tissue_normal-Connective_tissue_normal|TCGA-Bone_and_Soft_Tissue / Sample_Type by Project: Shred V9

CYP4A11 CYP4F2 CYP4A22 CYP4F3

3.43e-04154964b5604c0b0b9b283352a3f612f40883b9123475d1
ToppCellTCGA-Bone_and_Soft_Tissue-Solid_Tissue_Normal-Connective_tissue_normal-Connective_tissue_normal-1|TCGA-Bone_and_Soft_Tissue / Sample_Type by Project: Shred V9

CYP4A11 CYP4F2 CYP4A22 CYP4F3

3.43e-04154964160b170a3ade8b246843c9854af332475c047ba0
ToppCellCOVID-19-APC-like-Alveolar_macrophages|COVID-19 / group, cell type (main and fine annotations)

ECT2L CSF1R PLA2G4B ICA1L

3.61e-04156964735ade77cfa16b9386a0c7ec2bd14bd2e78a51ad
ToppCelltumor_Lung-B_lymphocytes-GC_B_cells_in_the_LZ|tumor_Lung / Location, Cell class and cell subclass

LAT2 CYB561A3 MEF2C PARP1

3.61e-04156964b5851474ba14dd2b4867415828b52dd98ecdd6d3
ToppCelldroplet-Liver-LIVER_NPC-30m-Myeloid-plasmacytoid_dendritic_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LAT2 CYB561A3 MEF2C WDR47

3.69e-04157964fc127e7720649e746f3d3f5c2e9e63784767106a
ToppCelldroplet-Liver-LIVER_NPC-30m-Myeloid-plasmacytoid_dendritic_cells|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LAT2 CYB561A3 MEF2C WDR47

3.69e-0415796466a191cef4aa00811bb04462310d012610006f85
ToppCellIIF-Lymphocyte-T_NK-ILC|IIF / Disease, Lineage and Cell Type

IPP DNAH1 PIM3 BAHCC1

3.87e-0415996455e4f21548f480ca414c00cbff5ec3b13bafd271
ToppCellTCGA-Uvea-Primary_Tumor-Uveal_Melanoma-Spindle_Cell|TCGA-Uvea / Sample_Type by Project: Shred V9

FAM86B2 FBXO17 ZNF835 DUOX1

3.97e-041609644eb8bcf1263252796941f7c1cd64b8fefa809d2b
ToppCellLeuk-UTI-Myeloid-tDC|Leuk-UTI / Disease, Lineage and Cell Type

CYB561A3 SUSD1 FAM83F POLQ

4.06e-0416196451b9f60986ed2e8e2297d31c80462c3ab65a2e5e
ToppCell356C-Myeloid-Macrophage-SPP1+_Macrophage|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

ANKS6 TMTC4 TNKS1BP1 PGBD5

4.36e-04164964d6806deabf5f5c355934387be2baae125ac33fb8
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c02-GPR183|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

RIOX1 ACAD10 ZNF835 CYP4F3

4.46e-041659643c8baed838eccb6e720bacb7458f087647dc1222
ToppCellPND01-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_B-B-B_prolif|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

LAT2 IPP SUSD1 POLQ

4.46e-0416596466f0364098d82629aa2ec1dfe0c5ad23de7c2c12
ToppCellNS-critical-d_07-13-Myeloid-pDC|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

CYB561A3 MEF2C ZNF835 SUSD1

4.46e-0416596417d5c4a111d9b5400780bc5e7b93ce2f5d69ceb7
ToppCell10x5'-Liver-Hematopoietic_progenitors|Liver / Manually curated celltypes from each tissue

KIF26B CDC20 POLQ BAHCC1

4.56e-04166964ae967570248cf86ca3ddf55e33bcbb3e4e3684bc
ToppCell10x5'-Liver-Hematopoietic_progenitors-Cycling_pre-Myeloid-2|Liver / Manually curated celltypes from each tissue

KIF26B CDC20 POLQ BAHCC1

4.56e-04166964a176e87aa6eec81d1fb79a028f759182d11b567d
ToppCellThalamus-Hematopoietic|Thalamus / BrainAtlas - Mouse McCarroll V32

MRC1 LAT2 CSF1R C2

4.56e-0416696476d60ac7ac5d1eaf530f0c741d9c48e0bd58396b
ToppCellfacs-MAT-Fat-18m-Myeloid-macrophage|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MRC1 LAT2 CSF1R UBASH3B

4.66e-04167964c2952d8ba763374c5678b92825c8956fc3e3ecd2
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-TAM-MG|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

LAT2 MEF2C CSF1R C2

4.66e-04167964942134bbabe9972fae80cbc4ed4e94da52f55dc3
ToppCell3'-Child09-12-SmallIntestine-Hematopoietic-B_cells-LZ_GC_cell|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

LAT2 CYB561A3 MEF2C PARP1

4.77e-0416896408eb1284f9b8bd3e0e4b21bfc2bbee01d35a0bd7
ToppCelldroplet-Liver-Npc-18m-Lymphocytic-B_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LAT2 CYB561A3 MEF2C CACNA1H

4.77e-04168964ce9fae8b295c668b0959d5007a8bcd401d80e258
ToppCell3'-Distal_airway-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophages-Alveolar_macrophages_L.1.0.4.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CYP27A1 AOC2 CAPN11 FITM1

4.77e-04168964eba865465feb0f42055bb8f98946050eeb03d177
ToppCellhealthy_donor-Myeloid-Monocytic-Neutrophil|healthy_donor / Disease condition, Lineage, Cell class and subclass

PCDHA13 CYP4F2 CYP4F3 IL1RAP

4.77e-0416896404259f5a9b067cd1b5619e34591e4b2fccc18535
ToppCelldroplet-Spleen-SPLEEN-1m-Myeloid-nan|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MRC1 CYP27A1 CSF1R C2

4.88e-041699643f8aa6d2f9aa060ae1a0ea3eb47e794099fc2c2c
ToppCelldroplet-Spleen-SPLEEN-1m-Myeloid|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MRC1 CYP27A1 CSF1R C2

4.88e-0416996426de495c7562e0740689d0f78e803698e3e793db
ToppCellE18.5-Immune-Immune_Myeloid-Monocytic-Macrophage-IM-IM_mature|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MRC1 CYP27A1 MEF2C CSF1R

4.99e-041709646ec0cf055ae55e9fac147f7989c47f83ab07270c
ToppCelldroplet-Lung-1m-Hematologic-myeloid-interstitial_macrophage|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ANKS6 ZDHHC14 MEF2C CSF1R

4.99e-04170964f664c7559e383b37845c123e41a3be316d869ba0
ToppCelldroplet-Kidney-nan-21m-Myeloid-nan|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ANKS6 LAT2 FBXO17 CSF1R

4.99e-04170964510625bd725d3590cffcd7acd1d42219f6eb1139
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_3|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

MYO9A KIF26B NLGN1 UBASH3B

4.99e-041709645d5f208682be21ed58320f5fc083a7898f8712da
ToppCelldroplet-Spleen-SPLEEN-1m-Myeloid-macrophage|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MRC1 CYP27A1 CSF1R C2

4.99e-04170964670027daec5a10dfa12246f1497b58db21d32a22
ToppCelldroplet-Lung-1m-Hematologic-myeloid-interstitial_macrophage-interstitial_macrophage_l12|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ANKS6 ZDHHC14 MEF2C CSF1R

4.99e-041709640272eb1487c2545d4aa06f5d1cd77f823e1441e9
ToppCellSevere-B_naive-11|Severe / disease group and sub_cluster of B and Plasma cells(res = 0.5)

LAT2 HLA-F CYB561A3 MEF2C

5.10e-041719647c2699f19ca38414447a286f7658f507882d57c2
ToppCelldroplet-Lung-nan-18m-Myeloid-Interstitial_Macrophage|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MRC1 ZDHHC14 MEF2C CSF1R

5.10e-041719647ca404539344e14dcd90c746c9122f713a7db78b
ToppCelldroplet-Lung-nan-18m-Myeloid-lung_macrophage|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MRC1 ZDHHC14 MEF2C CSF1R

5.10e-04171964ab113c8e773b0af47a87aed50e96be3ba71c3c82
ToppCelldroplet-Liver-Npc-18m-Lymphocytic-B_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LAT2 CYB561A3 MEF2C CACNA1H

5.10e-04171964584a095ddcbf78aa29527f84b46b5ad3e2edbaa9
ToppCelldroplet-Trachea-3m-Hematologic-myeloid-granulocyte-|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

MRC1 ZDHHC14 CSF1R POLQ

5.10e-0417196441932c9e70829ee3d55ca5fdb74d290fc8229416
ToppCellfacs-Lung-nan-3m-Lymphocytic-B_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CYB561A3 MEF2C CAPN11 PARP1

5.10e-04171964a31c23406cf6d6a17358a8fb41d392a7fb0306e0
ToppCellfacs-Lung-nan-3m-Lymphocytic-B_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CYB561A3 MEF2C CAPN11 PARP1

5.10e-0417196443d8fd9b9546e84a652564fe96b514b34b06262b
ToppCellfacs-Thymus-Flowthrough-3m-Myeloid|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LAT2 CYB561A3 MEF2C IL1RAP

5.21e-04172964356a66cd9303470e427005cc67fdd22a2c4bf971
ToppCellfacs-Thymus-Flowthrough-3m-Myeloid-macrophage|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LAT2 CYB561A3 MEF2C IL1RAP

5.21e-0417296446fadeee483fdf8402df92ec98575a09c6c15b16
ToppCellPND10-Immune-Immune_Myeloid-Monocytic-Macrophage-IM-IM_mature|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MRC1 CYP27A1 MEF2C CSF1R

5.21e-04172964f0e767a20d93e546ce278db67dbd779cc68af533
ToppCellfacs-Thymus-Flowthrough-3m-Myeloid-macrophage|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LAT2 CYB561A3 MEF2C IL1RAP

5.21e-04172964438d2e7f1897668a14d85ca70722e5d0102606dc
ToppCelldroplet-Lung-nan-3m-Myeloid-plasmacytoid_dendritic_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CYP27A1 ZDHHC14 CYB561A3 FAM83F

5.32e-041739641b9b4e165121b08ef15a93fca6bea875cae69f19
ToppCelltumor_Lymph_Node_/_Brain-Myeloid_cells-Pleural_Mac|tumor_Lymph_Node_/_Brain / Location, Cell class and cell subclass

MRC1 MEF2C CSF1R IL1RAP

5.32e-041739648384d533a1071fc65a06e6d9f5f17d8ab00c3966
ToppCelldroplet-Lung-LUNG-1m-Myeloid-Interstitial_Macrophage|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MRC1 ANKS6 ZDHHC14 MEF2C

5.32e-0417396426bba58f9fb215d1d155504906cd77e8774f6936
ToppCelldroplet-Lung-LUNG-1m-Myeloid-lung_macrophage|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MRC1 ANKS6 ZDHHC14 MEF2C

5.32e-0417396469b404e92aad3e6dff67e75466f073f20a71f13f
ToppCelldroplet-Lung-nan-3m-Myeloid-Plasmacytoid_Dendritic|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CYP27A1 ZDHHC14 CYB561A3 FAM83F

5.32e-04173964c25f24d7b672c9686d31ebc8d263042282f520fd
ToppCell5'-Adult-LargeIntestine-Hematopoietic-B_cells-Cycling_B_cell|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

LAT2 MEF2C PARP1 CDC20

5.32e-04173964b7e0193fd4983cb38d1bee441f608f73ee8743b9
ToppCelldroplet-Lung-18m-Hematologic-myeloid-interstitial_macrophage-interstitial_macrophage_l12|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

MRC1 ZDHHC14 MEF2C CSF1R

5.44e-0417496433e5903adb746f693433bdca11a75c508bbf50c0
ToppCellsaliva-Severe-critical_progression_d12-22_with-steroid-Myeloid-Macrophage-macrophage,_alveolar-Macro_c3-EREG|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

AOC2 MEF2C TNKS1BP1 BAHCC1

5.44e-04174964feed99acd868db61f045e666dbfdcaed91ca1488
ToppCellPND10-Immune-Immune_Myeloid-Monocytic-Macrophage-IM|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MRC1 CYP27A1 MEF2C CSF1R

5.44e-04174964f520b79d277e286c9bb5d091e6c94e7ec7e46699
ToppCelldroplet-Lung-18m-Hematologic-myeloid-interstitial_macrophage|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

MRC1 ZDHHC14 MEF2C CSF1R

5.44e-04174964ca0c2f42544092848541863c4a47b334e6828b8a
ToppCellIIF-Myeloid-pDC|IIF / Disease, Lineage and Cell Type

SELENOS KIF26B CYB561A3 BAHCC1

5.56e-0417596435cfb7d0b88678ff5b83ad6e19dbc15a908a3fcc
ToppCellE16.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-SCMF-SCMF_mature|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

AQP11 APBB3 TMTC4 PGBD5

5.56e-041759641d8aab491dcc27ea5dbfb6462d18ee280b21a05e
ToppCellPND07-Immune-Immune_Myeloid-Monocytic-Macrophage-IM-IM_mature|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MRC1 CYP27A1 MEF2C CSF1R

5.56e-04175964d983e80eeb11f341c564ea684e2b0b585a90ae58
ToppCellPND03-Immune-Immune_Myeloid-Monocytic-Macrophage-IM-IM_mature|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MRC1 CYP27A1 MEF2C CSF1R

5.56e-0417596453e6f1f8dd482dfa2539e068dacefbb6e08443bc
ToppCellE16.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-SCMF|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

AQP11 APBB3 TMTC4 PGBD5

5.56e-04175964427a7ee92fe16a90625946492062d37aa0f7235b
ToppCell367C-Myeloid-Dendritic-cDC_proliferating_1|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

ULBP3 PLEKHH1 CDC20 POLQ

5.56e-041759646b4e841bde6cfa4956e1a0231672cea20f11210c
ToppCellfacs-Brain_Non-Myeloid-Cerebellum_-18m-Myeloid-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LAT2 CYB561A3 CSF1R UBASH3B

5.68e-04176964d687e6c3f9043f2574d072f815b8c2258f9dc7b5
ToppCelldroplet-Kidney-KIDNEY-30m-Lymphocytic-plasma_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SELENOS LAT2 MEF2C CACNA1H

5.68e-0417696435610e7ac9902687e222641202409bab279c3998
ToppCelldroplet-Lung-LUNG-30m-Lymphocytic-Plasma_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MEF2C TMTC4 CACNA1H FUT8

5.68e-04176964606704098bfdf8bfef740a3544a372fae1e75969
ToppCellfacs-Brain_Non-Myeloid-Cerebellum_-18m-Myeloid|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LAT2 CYB561A3 CSF1R UBASH3B

5.68e-041769644f37854124d77ee64dcb40fd491eaed2ba389891
ToppCellfacs-Brain_Non-Myeloid-Cerebellum_-18m-Myeloid-microglial_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LAT2 CYB561A3 CSF1R UBASH3B

5.68e-041769640afba8707b847e5bdf6f38fe4379967631fe2240
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

MYO9A ZDHHC14 NLGN1 UBASH3B

5.68e-04176964327a3e81b724252e36d786de92a3ffd721ea6d7b
ToppCelldroplet-Lung-LUNG-30m-Lymphocytic-plasma_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MEF2C TMTC4 CACNA1H FUT8

5.68e-04176964acb9e29773030f6452a069f8f7e53eab68ab7bd3
ToppCelldroplet-Lung-LUNG-1m-Lymphocytic-plasma_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZDHHC14 PARP1 CACNA1H FUT8

5.80e-04177964c6812679aa6522d03bd29144e71c5fae6a92325e
ToppCelldroplet-Lung-LUNG-1m-Lymphocytic-Plasma_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZDHHC14 PARP1 CACNA1H FUT8

5.80e-04177964ff97398d2adb83063b7c53a264bfae86ea7ea304
ToppCell3'_v3-lymph-node_spleen-Myeloid_Mac-Intestinal_macrophages|lymph-node_spleen / Manually curated celltypes from each tissue

MRC1 CSF1R C2 ALG6

5.80e-0417796452c2ba74a8605260a2623e7d151286e504ac4d19
ToppCell3'-Broncho-tracheal-Endothelial-Blood_vessel_EC-capillary_endothelial_cell|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CYP4A11 MEF2C CAPN11 FGF23

5.80e-04177964fdf2af00fc971f0cd3915e1416e4a256458d6ea8
ToppCell3'-Broncho-tracheal-Endothelial-Blood_vessel_EC-capillary_endothelial_cell-EC_general_capillary|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CYP4A11 MEF2C CAPN11 FGF23

5.80e-0417796412f8627124acbf436e75681ff1ce429ff5e3f256
ToppCell3'-Broncho-tracheal-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophages-Alveolar_macrophages_L.1.0.3.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MRC1 CYP27A1 CSF1R C2

5.93e-041789640b398656f26c4061b11ccf98908d0e2e1367585a
ToppCell3'_v3-bone_marrow-Myeloid_Mac-Macrophage|bone_marrow / Manually curated celltypes from each tissue

MRC1 CYP27A1 CAPN11 C2

5.93e-0417896411a338032b59b936c5e65517c4160f7dd47a2cda
ToppCellEntopeduncular-Macroglia|Entopeduncular / BrainAtlas - Mouse McCarroll V32

SELENOS ARPC1A CYP27A1 NKX2-2

6.05e-04179964f61974710a60aa0618fdb30d864fb9bc7c05ef21
ToppCellfacs-Brain_Non-Myeloid-Hippocampus-24m-Lymphocytic-T_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LAT2 ACAD10 CSF1R CDC20

6.05e-0417996430efe1f0394c0edb27b91890b5c4637b73cbc5ec
Druglansoprazole

CYP4A11 CYP27A1 APBB3 CYP4F2 LCT CYP4A22 CYP4F3 CYP4F11

6.12e-0993978CID000003883
Drugmephenytoin

CYP4A11 CYP27A1 CYP4F2 CYP4A22 C2 CYP4F3 CYP4F11

9.80e-0888977CID000004060
Drugpropoxyphene

CYP4A11 CYP27A1 CYP4F2 CYP4A22 CYP4F3 CYP4F11

4.14e-0767976CID000010100
Drugcarteolol

CYP4A11 CYP27A1 CYP4F2 CYP4A22 CYP4F3 CYP4F11

6.37e-0772976CID000002583
Drugtrimipramine

CYP4A11 CYP27A1 CYP4F2 CYP4A22 CYP4F3 CYP4F11

1.19e-0680976CID000005584
Drugdiosmetin

CYP4A11 CYP27A1 CYP4F2 CYP4A22 CYP4F3 CYP4F11

1.70e-0685976CID005281612
Drugtienilic acid

CYP4A11 CYP27A1 CYP4F2 CYP4A22 CYP4F3 CYP4F11

2.89e-0693976CID000038409
Drughyamine hydroxide

AOC2 LCT C2

4.13e-068973CID000014842
DrugAC1L1KIN

CYP4A11 CYP27A1 CYP4F2 CYP4A22 CYP4F3 CYP4F11

4.41e-06100976CID000005516
DrugSparteinum

CYP4A11 CYP27A1 CYP4F2 CYP4A22 CYP4F3 CYP4F11

4.68e-06101976CID000003966
Drugsenkirkine

CYP4A11 CYP27A1 CYP4A22 CYP4F3 VPS13B

6.23e-0661975ctd:C009238
Drugfelodipine

CYP4A11 CYP27A1 CYP4F2 CYP4A22 CACNA1H CYP4F3 CYP4F11

8.03e-06169977CID000003333
Drugaminopyrine

CYP4A11 CYP27A1 CYP4F2 CYP4A22 C2 CYP4F3 CYP4F11

8.68e-06171977CID000006009
Drugoxygen

CYP4A11 CYP27A1 AOC2 CYP4F2 CYB561A3 CYP4A22 PAOX DUOX1 C2 CYP4F3 CYP4F11

9.14e-064999711CID000000977
DrugAC1Q7AUJ

CYP4A11 CYP27A1 CYP4F2 CYP4A22 CYP4F3 CYP4F11

1.09e-05117976CID000003303
Drug8-MOP

CYP4A11 CYP27A1 CYP4F2 CYP4A22 CYP4F3 CYP4F11

1.15e-05118976CID000004114
Drugmetyrapone

CYP4A11 CYP27A1 CYP4F2 LCT CYP4A22 CYP4F3 CYP4F11

1.17e-05179977CID000004174
Drug1-aminobenzotriazole

CYP4A11 CYP27A1 CYP4F2 SLC9A3 CYP4F3

1.32e-0571975CID000001367
Drughexobarbital

CYP4A11 CYP27A1 CYP4F2 CYP4A22 CYP4F3 CYP4F11

1.75e-05127976CID000003608
DrugSr23

CYB561A3 DGAT2L6

1.80e-052972CID000149963
Drug7-hydroxyoctanoate

ACAD10 LCT

1.80e-052972CID000167627
DrugN-(3-chloro-4-morpholin-4-yl) phenyl-N'-hydroxyimido formamide

CYP4A11 CYP4F2

1.80e-052972ctd:C503100
Drugalprazolam

CYP4A11 CYP27A1 CYP4F2 CYP4A22 CACNA1H CYP4F3 CYP4F11

1.90e-05193977CID000002118
Drugchloral hydrate

CYP4A11 CYP27A1 CYP4F2 CYP4A22 CYP4F3 CYP4F11

1.91e-05129976CID000002707
Drugtolbutamide

CYP4A11 CYP27A1 CYP4F2 CYP4A22 C2 CYP4F3 CYP4F11

2.24e-05198977CID000005505
Drugaminoglutethimide

CYP4A11 CYP27A1 CYP4F2 CYP4A22 CYP4F3 CYP4F11

2.68e-05137976CID000002145
DrugNSC640330

CYP4A11 CYP27A1 CYP4F2 ACAD10

5.22e-0548974CID000005204
Drugheliotrine

CYP4A11 CYP4A22 CYP4F3 VPS13B

5.22e-0548974ctd:C010178
DrugFucose

LCT FUT8

5.37e-053972ctd:D005643
Drugacisoga

AOC2 PAOX

5.37e-053972CID000129397
Drughalothane

CYP4A11 CYP27A1 CYP4F2 CYP4A22 C2 CACNA1H CYP4F3 CYP4F11

5.97e-05314978CID000003562
DrugFR h

AOC2 CYB561A3 C2

6.91e-0519973CID005288251
Drugparaoxon

CYP4A11 CYP27A1 CYP4F2 CYP4A22 CYP4F3 CYP4F11

7.33e-05164976CID000009395
Drug20-HETE

CYP4A11 CYP4F2 CYP4A22 SLC9A3 CYP4F3

9.12e-05106975CID005283157
Drugdocosanedioate

CYP4A11 CYP4F3

1.07e-044972CID000244872
Drugspermic acid

AOC2 PAOX

1.07e-044972CID000167029
Drug22-hydroxydocosanoic acid

CYP4A11 CYP4F3

1.07e-044972CID005282922
Drugdeferoxamine

CYP27A1 HLA-F CYP4F2 CYB561A3 CYP4A22 CSF1R CYP4F3 CYP4F11

1.10e-04343978CID000002973
DrugPhenoxybenzamine hydrochloride [63-92-3]; Down 200; 11.8uM; MCF7; HT_HG-U133A

THNSL1 ZDHHC14 PAOX FUT8 VPS13B SLC6A14

1.55e-041889766451_DN
DiseaseIntestinal Obstruction

SLC9A3 SLC6A14

2.69e-053892C0021843
DiseaseCYSTIC FIBROSIS MODIFIER 1

SLC9A3 SLC6A14

5.38e-054892C1859047
Diseaseplatelet-to-lymphocyte ratio

TRIM58 HLA-F ZBTB9 ACAD10 MEF2C TNKS1BP1 MICA

1.17e-04363897EFO_0008446
DiseaseX-14939 measurement

CYP4A11 CYP4A22

1.34e-046892EFO_0800747
Diseasehexadecenedioate (C16:1-DC) measurement

CYP4F2 CYP4F11

3.19e-049892EFO_0800562
Diseaseplatelet measurement

TRIM58 ZDHHC14 ACAD10 MEF2C PARP1 MICA

3.90e-04315896EFO_0005036
Diseasetotal blood protein measurement

ZSWIM8 LAT2 IPP DNAH1 PARP1 CSF1R UBASH3B

4.25e-04449897EFO_0004536
Diseaseautosomal recessive polycystic kidney disease (biomarker_via_orthology)

CYP4A11 CYP4A22

4.86e-0411892DOID:0110861 (biomarker_via_orthology)
Diseaseserum metabolite measurement

TRIM58 CYP4A11 KIF26B ARPC1A IPP CYP4F2 PAOX SLC9A3 CSF1R

2.20e-03945899EFO_0005653
Diseasevisceral adipose tissue measurement, body mass index

PCDHAC1 PCDHA13 MICA

2.34e-0387893EFO_0004340, EFO_0004765
Diseasegastric carcinoma

HLA-F ASH1L MICA

2.50e-0389893EFO_0000178

Protein segments in the cluster

PeptideGeneStartEntry
YNGHLTIWFTDTSAL

C21orf62

76

Q9NYP8
AYRGSHPTTSQIWFS

BAHCC1

101

Q9P281
DNIHSASLYTRWNGI

ASH1L

2386

Q9NR48
SHSARVGSLSWNSYI

CDC20

266

Q12834
VGSLSWNSYILSSGS

CDC20

271

Q12834
WNSYILSSGSRSGHI

CDC20

276

Q12834
TVRWTVSLNSYSGAG

ALG6

16

Q9Y672
TASGISWILYALATH

CYP4A11

326

Q02928
SHRWTHLGGSTYRAV

ACAD10

31

Q6JQN1
TGIATGSYQHILSDW

ECT2L

421

Q008S8
LAGHSSAWQAYLSLS

DNHD1

4006

Q96M86
HTTFYEGSWRRGSSA

CAPN11

391

Q9UMQ6
WVHGVSFSASGSRLA

ARPC1A

206

Q92747
SWKHGSGTQYVSTRQ

C18orf25

356

Q96B23
RSSDAHSSWYNGRSE

RBMX2

271

Q9Y388
SGYALGSSNWIIQSH

INTS9

216

Q9NV88
QYWTTVSSLHQARSG

IPP

321

Q9Y573
LTDTWAGSHSLRYFS

HLA-F

16

P30511
WHGSRTTNFAGILSQ

PARP1

861

P09874
HSLRYNLTVLSWDGS

MICA

26

Q29983
GNLVVSSLWSFTFGH

AOC2

321

O75106
SAIYGSSHSWSDALR

DUOX1

176

Q9NRD9
HGTTGLVTWDAALYL

FAM86B2

131

P0C5J1
SAALTSSGELYTWGL

HERC2

3111

O95714
FNYSTAHSAGLTLIW

IL1RAP

56

Q9NPH3
TLSHGWAPGSLLTYS

C2

36

P06681
AHQYLDGTWSLSRTN

KIF26B

311

Q2KJY2
DGTWSLSRTNGVTLY

KIF26B

316

Q2KJY2
SHGTTGLVTWDAALY

FAM86B1

96

Q8N7N1
GTLYNSSALVNTGLW

FAM135A

1361

Q9P2D6
RGGSSLRHVVYWNSS

EFNA4

21

P52798
NLGVSHYRFSISWSR

LCT

1441

P09848
FNTASALHLGSVTGW

MEF2C

336

Q06413
ITGASGSTWALANLY

PLA2G4B

331

P0C869
TLSHYSEGNRWSNST

NLGN1

311

Q8N2Q7
ESSGHKRSSSWGRTY

RALGAPA2

471

Q2PPJ7
LAAWETGSGQLHYSV

PCDHA13

21

Q9Y5I0
GSNAWLSYHISRASD

PCDHAC1

591

Q9H158
LSIWSGGFYSNRSLA

PGBD5

186

Q8N414
SSWVGHYGALVTHSS

FBXO17

256

Q96EF6
YSDVSTGLTWRSGTA

FZD8

666

Q9H461
NQSEWRYLLSGGSIS

DNAH1

3541

Q9P2D7
ESSLDRSNSLSWYGG

APBB3

91

O95704
AHWQTYVSGTLRFGI

CEPT1

196

Q9Y6K0
PHWTLYSDGSSSILS

CSF1R

56

P07333
RSVSYWNVSSTQHGG

FASTKD5

26

Q7L8L6
CLAAGHQWRGYTVSS

FITM1

171

A5D6W6
LTYDWNTHSQGGRRS

DGAT2L6

56

Q6ZPD8
WGGLIHLYTATARNS

FGF23

36

Q9GZV9
TGTRQNHSFIWSGAS

POLQ

1621

O75417
DTTASGLSWVLYHLA

CYP4F11

331

Q9HBI6
TASGISWILYALATH

CYP4A22

326

Q5TCH4
GVDTTSNTLTWALYH

CYP27A1

336

Q02318
GSSHLISTSSWRDGQ

CEP350

416

Q5VT06
GASVNSRNHYGWSAL

ANKS6

101

Q68DC2
DTTASGLSWVLYHLA

CYP4F2

331

P78329
AVGTNSTLHYVWSSL

GLMP

61

Q8WWB7
LSWNHFILSSGSRLG

CDC20B

321

Q86Y33
SLGTGLYTSSAWLVV

IGFN1

381

Q86VF2
DTTASGLSWVLYHLA

CYP4F3

331

Q08477
ANLYSLHSWLGITTV

CYB561A3

111

Q8NBI2
STLGISKRTTGYWSH

HSDL1

281

Q3SXM5
SHSLTTYQRTLLGFW

ICA1L

221

Q8NDH6
GLLSGEHAYLQSSWN

CACNA1H

1351

O95180
RTFYSTTHGALLSGW

PAOX

476

Q6QHF9
QQTIWRLITASGSYH

MRC1

696

P22897
SFTGSRTYSLVGQAW

LAT2

51

Q9GZY6
SISWSAGLHNRYTEN

FUT8

431

Q9BYC5
RTTAYNIWAVTGHFS

TAS2R45

81

P59539
LHGWTGTGKSYVSSL

TOR2A

91

Q8N2E6
TVWNAATTGLSLYGV

SLC9A3

151

P48764
ISSSHLQALWIGYST

TANC1

881

Q9C0D5
WLASTEGLQYSLHGL

NKX2-2

76

O95096
TQLLAGERHSLWYST

TBC1D26

211

Q86UD7
TGSYRFTWSSSHVDR

FAM83F

256

Q8NEG4
LHLTLSTYQRNTWGD

RIOX1

416

Q9H6W3
SALWSLGLTQYHVSE

AQP11

136

Q8NBQ7
SWGSSLAGAQSYSLH

C11orf53

151

Q8IXP5
FLHTTVGSLLATYGW

SELENOS

21

Q9BQE4
LHGWTGTGKSYVSSL

TOR2A

91

Q5JU69
TGRADAHSLWYNFTI

ULBP3

26

Q9BZM4
WGSRLSSNTSHKSYR

TMTC4

71

Q5T4D3
FTWSHDGTQALISYR

TULP4

131

Q9NRJ4
LSGHTGHILALYTWS

WDR47

751

O94967
HAGSTRGSLLSWSSA

USP43

741

Q70EL4
LQSSSWRAGSQHGAY

SPEM3

1101

A0A1B0GUW6
RSFSTGSDLGHWVTT

SLC25A46

31

Q96AG3
LGQRWYLANFSHATS

SUSD1

431

Q6UWL2
RLWGSRLTFNHDGSS

TNKS1BP1

181

Q9C0C2
AWIRDYSSGGSSRTL

TNKS1BP1

956

Q9C0C2
NGYGHWIASTSGSRS

TBC1D23

451

Q9NUY8
YGTILSSANSINWGR

THNSL1

461

Q8IYQ7
YHGRSATVWSLGVLL

PIM3

221

Q86V86
TWLYHLTVAAGGSSA

PLEKHH1

786

Q9ULM0
SVWSIVGLSGFHTYL

ZDHHC14

261

Q8IZN3
YHALLSTTSSTGGWC

ZBTB9

156

Q96C00
WYSVRTSASHSSASG

ZSWIM8

386

A7E2V4
SRTYSSHVSWITGQA

ZSWIM8

1301

A7E2V4
FWLYEQTAGGSSTAR

ZSWIM8

1421

A7E2V4
IYQSWSHLGNVSSSA

VPS13B

811

Q7Z7G8
SQGSYLASHWRTHTG

ZNF835

176

Q9Y2P0
STWIFHGSYSILNTS

UBASH3B

321

Q8TF42
HQGRSSSSGHYVSWV

USP14

426

P54578
YSLSVAWGGLVALSS

SLC6A14

321

Q9UN76
TSSSSGYDWHQAALA

TSHZ1

191

Q6ZSZ6
LGLQSFSSGRHYWEV

TRIM58

336

Q8NG06
RNTYGRLNSGSWSLT

ZNF324B

71

Q6AW86
NLDGSIHYGSLQSWL

MYO9A

111

B2RTY4