Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
Domain	BNIP3	BNIP3 BNIP3L	2.30e-05	2	90	2	IPR010548
Domain	BNIP3	BNIP3 BNIP3L	2.30e-05	2	90	2	PF06553
Domain	GABAAb_rcpt	GABRB1 GABRB3	6.87e-05	3	90	2	IPR002289
Domain	EGF_CA	HMCN2 LRP4 VWA2 F12 STAB1	3.09e-04	122	90	5	SM00179
Domain	EGF-like_Ca-bd_dom	HMCN2 LRP4 VWA2 F12 STAB1	3.33e-04	124	90	5	IPR001881
Domain	PH_BEACH	NBEAL1 LYST	3.40e-04	6	90	2	PF14844
Domain	PH-BEACH_dom	NBEAL1 LYST	6.31e-04	8	90	2	IPR023362
Domain	-	NBEAL1 LYST	6.31e-04	8	90	2	2.30.29.40
Domain	PH_BEACH	NBEAL1 LYST	6.31e-04	8	90	2	PS51783
Domain	BEACH_dom	NBEAL1 LYST	8.09e-04	9	90	2	IPR000409
Domain	BEACH	NBEAL1 LYST	8.09e-04	9	90	2	PS50197
Domain	Beach	NBEAL1 LYST	8.09e-04	9	90	2	PF02138
Domain	-	NBEAL1 LYST	8.09e-04	9	90	2	1.10.1540.10
Domain	Beach	NBEAL1 LYST	8.09e-04	9	90	2	SM01026
Domain	TPR_7	TTC24 TTC28	1.01e-03	10	90	2	PF13176
Domain	CRAL_TRIO_N	CLVS2 TTPA	1.23e-03	11	90	2	PF03765
Domain	CRAL-bd_toc_tran	CLVS2 TTPA	1.47e-03	12	90	2	IPR001071
Domain	CRAL_TRIO_N	CLVS2 TTPA	1.47e-03	12	90	2	SM01100
Domain	LINK	HAPLN2 STAB1	1.73e-03	13	90	2	SM00445
Domain	Link_dom	HAPLN2 STAB1	1.73e-03	13	90	2	IPR000538
Domain	Xlink	HAPLN2 STAB1	1.73e-03	13	90	2	PF00193
Domain	LINK_1	HAPLN2 STAB1	1.73e-03	13	90	2	PS01241
Domain	LINK_2	HAPLN2 STAB1	1.73e-03	13	90	2	PS50963
Domain	CRAL/TRIO_N_dom	CLVS2 TTPA	2.31e-03	15	90	2	IPR011074
Domain	EGF	LRP4 VWA2 F12 STAB1	3.23e-03	126	90	4	PF00008
Domain	CRAL_TRIO	CLVS2 TTPA	4.54e-03	21	90	2	PF00650
Pubmed	GABAA receptors involved in sleep and anaesthesia: β1- versus β3-containing assemblies.	GABRB1 GABRB3	7.38e-06	2	95	2	21735059
Pubmed	The expression of Tousled kinases in CaP cell lines and its relation to radiation response and DSB repair.	TLK2 TLK1	7.38e-06	2	95	2	21647934
Pubmed	Epileptic encephalopathy de novo GABRB mutations impair γ-aminobutyric acid type A receptor function.	GABRB1 GABRB3	7.38e-06	2	95	2	26950270
Pubmed	Multiple modes for conferring surface expression of homomeric beta1 GABAA receptors.	GABRB1 GABRB3	7.38e-06	2	95	2	18650446
Pubmed	Uncovering interactions of mitochondrial proteins BNIP3 and BNIP3L with necroptosis-associated kinase RIPK3: Insights into kinase activation.	BNIP3 BNIP3L	7.38e-06	2	95	2	37419035
Pubmed	The MAP Kinase Phosphatase MKP-1 Modulates Neurogenesis via Effects on BNIP3 and Autophagy.	BNIP3 DUSP1	7.38e-06	2	95	2	34944516
Pubmed	Placental localization and expression of the cell death factors BNip3 and Nix in preeclampsia, intrauterine growth retardation and HELLP syndrome.	BNIP3 BNIP3L	7.38e-06	2	95	2	16219518
Pubmed	Tousled-Like Kinases Suppress Innate Immune Signaling Triggered by Alternative Lengthening of Telomeres.	TLK2 TLK1	7.38e-06	2	95	2	32755577
Pubmed	cDNA cloning and chromosomal mapping of genes encoding novel protein kinases termed PKU-alpha and PKU-beta, which have nuclear localization signal.	TLK2 TLK1	7.38e-06	2	95	2	9427565
Pubmed	Mitochondrial autophagy: Origins, significance, and role of BNIP3 and NIX.	BNIP3 BNIP3L	7.38e-06	2	95	2	25753537
Pubmed	Protection of Quiescence and Longevity of IgG Memory B Cells by Mitochondrial Autophagy.	BNIP3 BNIP3L	7.38e-06	2	95	2	35101890
Pubmed	Mitochondrial proteins Bnip3 and Bnip3L are involved in anthrax lethal toxin-induced macrophage cell death.	BNIP3 BNIP3L	7.38e-06	2	95	2	17623653
Pubmed	BNIP3 and Nix: Atypical regulators of cell fate.	BNIP3 BNIP3L	7.38e-06	2	95	2	35863652
Pubmed	Acetyl-Coenzyme A acyltransferase 2 attenuates the apoptotic effects of BNIP3 in two human cell lines.	BNIP3 ACAA2	7.38e-06	2	95	2	18371312
Pubmed	Mitophagy mediated by BNIP3 and NIX protects against ferroptosis by downregulating mitochondrial reactive oxygen species.	BNIP3 BNIP3L	7.38e-06	2	95	2	38519771
Pubmed	High factor VIII activity, high plasminogen activator inhibitor 1 antigen levels and low factor XII activity contribute to a thrombophilic tendency in elderly venous thromboembolism patients.	F8 F12	7.38e-06	2	95	2	21071930
Pubmed	Analysis of BNIP3 and BNIP3L/Nix expression in cybrid cell lines harboring two LHON-associated mutations.	BNIP3 BNIP3L	7.38e-06	2	95	2	31584786
Pubmed	Internalized Receptor for Glucose-dependent Insulinotropic Peptide stimulates adenylyl cyclase on early endosomes.	GIPR GNAS	7.38e-06	2	95	2	27641811
Pubmed	The outer mitochondrial membrane protein TMEM11 demarcates spatially restricted BNIP3/BNIP3L-mediated mitophagy.	BNIP3 BNIP3L	2.21e-05	3	95	2	36795401
Pubmed	Discovery of Stromal Regulatory Networks that Suppress Ras-Sensitized Epithelial Cell Proliferation.	TLK2 TLK1	2.21e-05	3	95	2	28535374
Pubmed	The histone H3K9 demethylase KDM3A promotes anoikis by transcriptionally activating pro-apoptotic genes BNIP3 and BNIP3L.	BNIP3 BNIP3L	2.21e-05	3	95	2	27472901
Pubmed	BNIP3 and NIX mediate Mieap-induced accumulation of lysosomal proteins within mitochondria.	BNIP3 BNIP3L	2.21e-05	3	95	2	22292033
Pubmed	The glucose-dependent insulinotropic polypeptide receptor is overexpressed amongst GNAS1 mutation-negative somatotropinomas and drives growth hormone (GH)-promoter activity in GH3 cells.	GIPR GNAS	2.21e-05	3	95	2	21554434
Pubmed	The TLK-ASF1 histone chaperone pathway plays a critical role in IL-1β-mediated AML progression.	TLK2 TLK1	2.21e-05	3	95	2	38498025
Pubmed	A novel GIP receptor splice variant influences GIP sensitivity of pancreatic beta-cells in obese mice.	GIPR GNAS	2.21e-05	3	95	2	17971513
Pubmed	BNIP3 (BCL2 interacting protein 3) regulates pluripotency by modulating mitochondrial homeostasis via mitophagy.	BNIP3 BNIP3L	2.21e-05	3	95	2	35410319
Pubmed	DUSP1 alleviates cardiac ischemia/reperfusion injury by suppressing the Mff-required mitochondrial fission and Bnip3-related mitophagy via the JNK pathways.	BNIP3 DUSP1	2.21e-05	3	95	2	29149759
Pubmed	Histamine action on vertebrate GABAA receptors: direct channel gating and potentiation of GABA responses.	GABRB1 GABRB3	2.21e-05	3	95	2	18281286
Pubmed	GABAA receptor beta 1, beta 2, and beta 3 subunits: comparisons in DBA/2J and C57BL/6J mice.	GABRB1 GABRB3	2.21e-05	3	95	2	7893750
Pubmed	Expression and distribution of GABAA receptor subtypes in human alcoholic cerebral cortex.	GABRB1 GABRB3	2.21e-05	3	95	2	11085308
Pubmed	Excessive BNIP3- and BNIP3L-dependent mitophagy underlies the pathogenesis of FBXL4-mutated mitochondrial DNA depletion syndrome.	BNIP3 BNIP3L	2.21e-05	3	95	2	37876279
Pubmed	GABAA receptor beta subunit mRNA expression in the human alcoholic brain.	GABRB1 GABRB3	2.21e-05	3	95	2	15337300
Pubmed	Differential expression of GABAA/benzodiazepine receptor beta 1, beta 2, and beta 3 subunit mRNAs in the developing mouse cerebellum.	GABRB1 GABRB3	2.21e-05	3	95	2	1282920
Pubmed	Synergism between factor XII -4C>T and factor XIII Val34Leu polymorphisms in fibrinolytic therapy in acute myocardial infarction.	F8 F12	2.21e-05	3	95	2	20589311
Pubmed	Mieap-induced accumulation of lysosomes within mitochondria (MALM) regulates gastric cancer cell invasion under hypoxia by suppressing reactive oxygen species accumulation.	BNIP3 BNIP3L	2.21e-05	3	95	2	30808977
Pubmed	FBXL4 ubiquitin ligase deficiency promotes mitophagy by elevating NIX levels.	BNIP3 BNIP3L	4.41e-05	4	95	2	37102372
Pubmed	BNIP3- and BNIP3L-Mediated Mitophagy Promotes the Generation of Natural Killer Cell Memory.	BNIP3 BNIP3L	4.41e-05	4	95	2	26253785
Pubmed	PPTC7 antagonizes mitophagy by promoting BNIP3 and NIX degradation via SCFFBXL4.	BNIP3 BNIP3L	4.41e-05	4	95	2	38992176
Pubmed	Mammalian homologues of the plant Tousled gene code for cell-cycle-regulated kinases with maximal activities linked to ongoing DNA replication.	TLK2 TLK1	4.41e-05	4	95	2	10523312
Pubmed	Nix and Nip3 form a subfamily of pro-apoptotic mitochondrial proteins.	BNIP3 BNIP3L	4.41e-05	4	95	2	9867803
Pubmed	Identification of human Asf1 chromatin assembly factors as substrates of Tousled-like kinases.	TLK2 TLK1	4.41e-05	4	95	2	11470414
Pubmed	Beta Interferon Production Is Regulated by p38 Mitogen-Activated Protein Kinase in Macrophages via both MSK1/2- and Tristetraprolin-Dependent Pathways.	RPS6KA4 DUSP1	4.41e-05	4	95	2	27795299
Pubmed	The physical and genetic map surrounding the Lyst gene on mouse chromosome 13.	LYST RYR2	4.41e-05	4	95	2	9070932
Pubmed	Phosphorylation-mediated control of histone chaperone ASF1 levels by Tousled-like kinases.	TLK2 TLK1	4.41e-05	4	95	2	20016786
Pubmed	Hypoxia-induced autophagy is mediated through hypoxia-inducible factor induction of BNIP3 and BNIP3L via their BH3 domains.	BNIP3 BNIP3L	7.34e-05	5	95	2	19273585
Pubmed	The brefeldin A-inhibited GDP/GTP exchange factor 2, a protein involved in vesicular trafficking, interacts with the beta subunits of the GABA receptors.	GABRB1 GABRB3	7.34e-05	5	95	2	15198677
Pubmed	Bnip3 mediates the hypoxia-induced inhibition on mammalian target of rapamycin by interacting with Rheb.	BNIP3 BNIP3L	7.34e-05	5	95	2	17928295
Pubmed	Tousled-like kinase in a microbial eukaryote regulates spindle assembly and S-phase progression by interacting with Aurora kinase and chromatin assembly factors.	TLK2 TLK1	7.34e-05	5	95	2	17940067
Pubmed	A-kinase anchoring protein 79/150 facilitates the phosphorylation of GABA(A) receptors by cAMP-dependent protein kinase via selective interaction with receptor beta subunits.	GABRB1 GABRB3	7.34e-05	5	95	2	12595241
Pubmed	Insensitivity to anaesthetic agents conferred by a class of GABA(A) receptor subunit.	GABRB1 GABRB3	7.34e-05	5	95	2	9039914
Pubmed	Hypoxia signals autophagy in tumor cells via AMPK activity, independent of HIF-1, BNIP3, and BNIP3L.	BNIP3 BNIP3L	7.34e-05	5	95	2	18551130
Pubmed	FBXL4 suppresses mitophagy by restricting the accumulation of NIX and BNIP3 mitophagy receptors.	BNIP3 BNIP3L	7.34e-05	5	95	2	37161784
Pubmed	CBFβ stabilizes HIV Vif to counteract APOBEC3 at the expense of RUNX1 target gene expression.	TTC28 HLA-DQB1 DUSP1 DHCR7 SLC6A20	8.77e-05	163	95	5	23333304
Pubmed	Large-scale meta-analysis of genome-wide association data identifies six new risk loci for Parkinson's disease.	GAK HLA-DQB1 BCKDK	1.01e-04	33	95	3	25064009
Pubmed	Rectification of muscle and nerve deficits in paralyzed ryanodine receptor type 1 mutant embryos.	LRP4 RYR2	1.10e-04	6	95	2	26025922
Pubmed	Human Tousled like kinases are targeted by an ATM- and Chk1-dependent DNA damage checkpoint.	TLK2 TLK1	1.10e-04	6	95	2	12660173
Pubmed	Evolution of GABA(A) receptor diversity in the human genome.	GABRB1 GABRB3	1.10e-04	6	95	2	10023064
Pubmed	The GABAA Receptor β Subunit Is Required for Inhibitory Transmission.	GABRB1 GABRB3	1.10e-04	6	95	2	29706582
Pubmed	BNIP3alpha: a human homolog of mitochondrial proapoptotic protein BNIP3.	BNIP3 BNIP3L	1.10e-04	6	95	2	9973195
Pubmed	A novel adenovirus E1B19K-binding protein B5 inhibits apoptosis induced by Nip3 by forming a heterodimer through the C-terminal hydrophobic region.	BNIP3 BNIP3L	1.54e-04	7	95	2	10381623
Pubmed	Lamina-specific alterations in cortical GABA(A) receptor subunit expression in schizophrenia.	GABRB1 GABRB3	1.54e-04	7	95	2	20843900
Pubmed	Mitophagy mediated by BNIP3 and BNIP3L/NIX in urothelial cells of the urinary bladder of cattle harbouring bovine papillomavirus infection.	BNIP3 BNIP3L	1.54e-04	7	95	2	31500722
Pubmed	Segmentation defects of Notch pathway mutants and absence of a synergistic phenotype in lunatic fringe/radical fringe double mutant mice.	MESP2 RFNG	2.05e-04	8	95	2	12001066
Pubmed	GABA(A) receptor cell surface number and subunit stability are regulated by the ubiquitin-like protein Plic-1.	GABRB1 GABRB3	2.05e-04	8	95	2	11528422
Pubmed	Comparative mapping in the beige-satin region of mouse chromosome 13.	LYST RYR2	3.28e-04	10	95	2	9027500
Pubmed	Late-gestational systemic hypoxia leads to a similar early gene response in mouse placenta and developing brain.	BNIP3 DUSP1	3.28e-04	10	95	2	20926767
Pubmed	BNIP3 is an RB/E2F target gene required for hypoxia-induced autophagy.	BNIP3 BNIP3L	3.28e-04	10	95	2	17576813
Pubmed	An inter-species protein-protein interaction network across vast evolutionary distance.	PRPSAP1 GAK BNIP3 BNIP3L BCKDK RAD54B PYCR3	3.68e-04	483	95	7	27107014
Pubmed	A comprehensive SARS-CoV-2-human protein-protein interactome reveals COVID-19 pathobiology and potential host therapeutic targets.	PRPSAP1 HK3 ATP13A1 MORF4L1 ACAA2 SAMM50 SIPA1	4.69e-04	503	95	7	36217030
Pubmed	Chromosomal localization of GABAA receptor subunit genes: relationship to human genetic disease.	GABRB1 F8	4.79e-04	12	95	2	2561974
Pubmed	Genetic variants within the MAP kinase signalling network and anti-TNF treatment response in rheumatoid arthritis patients.	RPS6KA4 DUSP1	4.79e-04	12	95	2	20805296
Pubmed	The Catalytically Inactive Mutation of the Ubiquitin-Conjugating Enzyme CDC34 Affects its Stability and Cell Proliferation.	WDR6 ACO2 DHCR7 ACAA2 SAMM50	4.96e-04	237	95	5	29564676
Pubmed	Mitochondrial phosphoproteome revealed by an improved IMAC method and MS/MS/MS.	BNIP3 BCKDK ACAA2	5.19e-04	57	95	3	17208939
Pubmed	A gene encoding a putative GTPase regulator is mutated in familial amyotrophic lateral sclerosis 2.	NBEAL1 MPP4	5.65e-04	13	95	2	11586298
Pubmed	Genetic and physical delineation of the region overlapping the progressive motor neuropathy (pmn) locus on mouse chromosome 13.	LYST RYR2	6.58e-04	14	95	2	11472062
Pubmed	The biochemical anatomy of cortical inhibitory synapses.	GABRB1 GABRB3	6.58e-04	14	95	2	22768092
Pubmed	Genome-wide siRNA screen reveals amino acid starvation-induced autophagy requires SCOC and WAC.	TLK2 WDR6	6.58e-04	14	95	2	22354037
Pubmed	Characterization of the Cardiac Overexpression of HSPB2 Reveals Mitochondrial and Myogenic Roles Supported by a Cardiac HspB2 Interactome.	DUSP1 ACAA2 SAMM50 RYR2	7.24e-04	147	95	4	26465331
Pubmed	H19 acts as a trans regulator of the imprinted gene network controlling growth in mice.	RTL1 GNAS	7.57e-04	15	95	2	19762426
Pubmed	Germline genomic variants associated with childhood acute lymphoblastic leukemia.	OR2C3 RYR2	7.57e-04	15	95	2	19684603
Pubmed	Large-scale mapping of human protein-protein interactions by mass spectrometry.	PRPSAP1 TLK2 TLK1 RADIL MORF4L1 DHCR7 BCKDK RAD54B GNAS IRGQ CPSF2	7.62e-04	1284	95	11	17353931
Pubmed	Shotgun sequencing of the human transcriptome with ORF expressed sequence tags.	FREM2 NBEAL1 RAD54B GNAS VWA2 LYST STAB1	8.10e-04	552	95	7	10737800
Pubmed	Differential requirements for Tousled-like kinases 1 and 2 in mammalian development.	TLK2 TLK1	9.78e-04	17	95	2	28708136
Pubmed	Exome sequencing reveals pathogenic mutations in 91 strains of mice with Mendelian disorders.	FREM2 LRP4 LYST	1.03e-03	72	95	3	25917818
Pubmed	The HECT type ubiquitin ligase NEDL2 is degraded by anaphase-promoting complex/cyclosome (APC/C)-Cdh1, and its tight regulation maintains the metaphase to anaphase transition.	RADIL RPS6KA4 HECW2 RAD54B CPSF2	1.06e-03	281	95	5	24163370
Pubmed	HIV-1 Nef promotes endocytosis of cell surface MHC class II molecules via a constitutive pathway.	HLA-DQB1 LYST	1.10e-03	18	95	2	19620308
Pubmed	Strong genetic evidence for a selective influence of GABAA receptors on a component of the bipolar disorder phenotype.	GABRB1 GABRB3	1.10e-03	18	95	2	19078961
Pubmed	GABA neurotransmitter signaling in the developing mouse lens: dynamic regulation of components and functionality.	GABRB1 GABRB3	1.10e-03	18	95	2	18985723
Pubmed	ER-export and ARFRP1/AP-1-dependent delivery of SARS-CoV-2 Envelope to lysosomes controls late stages of viral replication.	BNIP3 ATP13A1 WDR6 TMEM87B DHCR7 SAMM50 GNAS TRAPPC8 PIGO	1.19e-03	952	95	9	38569033
Pubmed	SCFFBXL¹⁵ regulates BMP signalling by directing the degradation of HECT-type ubiquitin ligase Smurf1.	HECW2 FBXL5	1.22e-03	19	95	2	21572392
Pubmed	Follow-up examination of linkage and association to chromosome 1q43 in multiple sclerosis.	OPN3 RYR2	1.36e-03	20	95	2	19626040
Pubmed	Activation of amino acid metabolic program in cardiac HIF1-alpha-deficient mice.	BNIP3 BNIP3L	1.36e-03	20	95	2	33665549
Pubmed	Comparative analysis of apoptosis and inflammation genes of mice and humans.	BNIP3 BNIP3L NLRP5	1.39e-03	80	95	3	12819136
Pubmed	Phosphoproteome analysis of functional mitochondria isolated from resting human muscle reveals extensive phosphorylation of inner membrane protein complexes and enzymes.	ACO2 BCKDK SAMM50	1.50e-03	82	95	3	20833797
Pubmed	Early growth response 1 (Egr-1) directly regulates GABAA receptor α2, α4, and θ subunits in the hippocampus.	GABRB1 GABRB3	1.50e-03	21	95	2	25708312
Pubmed	Discovery and characterization of spontaneous mouse models of craniofacial dysmorphology.	FREM2 LRP4	1.50e-03	21	95	2	26234751
Pubmed	Glucocorticoid receptor is required for foetal heart maturation.	DUSP1 RYR2	1.65e-03	22	95	2	23595884
Pubmed	Vectorial proteomics reveal targeting, phosphorylation and specific fragmentation of polymerase I and transcript release factor (PTRF) at the surface of caveolae in human adipocytes.	ACAA2 GNAS	1.65e-03	22	95	2	15242332
Pubmed	Combinatorial CRISPR screen identifies fitness effects of gene paralogues.	TLK2 TLK1 GAK USP35	1.73e-03	186	95	4	33637726
Pubmed	Endoglin Protein Interactome Profiling Identifies TRIM21 and Galectin-3 as New Binding Partners.	PRPSAP1 BCKDK ESAM PYCR3	1.73e-03	186	95	4	31540324
GeneFamily	WD repeat domain containing\|BEACH domain containing	NBEAL1 LYST	4.37e-04	9	64	2	1230
ToppCell	CV-Mild-4\|Mild / Virus stimulation, Condition and Cluster	CCNG2 BNIP3 BNIP3L HLA-DQB1 NR6A1 HAS3	1.23e-06	160	95	6	2e24f8de5086b086863d3bf4d9afbd9bc93f4d5e
ToppCell	Severe-B_naive-11\|World / disease group and sub_cluster of B and Plasma cells(res = 0.5)	GABRB1 RADIL HLA-DQB1 DUSP1 KLHL33 STAB1	1.28e-06	161	95	6	ad3b58e3a8b59a609c8d2d2690d15218d18eabbd
ToppCell	CV-Mild-4\|CV / Virus stimulation, Condition and Cluster	CCNG2 BNIP3 BNIP3L HLA-DQB1 HAS3	2.39e-05	160	95	5	be89efeeecb0de96ce136a7a62738f15dc0badb2
ToppCell	E16.5-Endothelial-Endothelial_lymphatic\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	KBTBD11 GNAS SIPA1 F8 STAB1	2.94e-05	167	95	5	b93103a868fba63a8910bffb690a6242b9252833
ToppCell	E16.5-Endothelial-Endothelial_lymphatic-Lymphatic_EC-LEC\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	KBTBD11 GNAS SIPA1 F8 STAB1	2.94e-05	167	95	5	fcd583b1efd0ac883379982ea8e6c54f2c0be268
ToppCell	E16.5-Endothelial-Endothelial_lymphatic-Lymphatic_EC\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	KBTBD11 GNAS SIPA1 F8 STAB1	2.94e-05	167	95	5	f6bc63138b7239211fa5f27a8dc799b6e022c0f8
ToppCell	E16.5-Endothelial-Endothelial_lymphatic-Lymphatic_EC-LEC-LEC_mature\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	KBTBD11 GNAS SIPA1 F8 STAB1	2.94e-05	167	95	5	26cd8ee5e826e71eaf58d10a906543a6932fb3f9
ToppCell	CV-Healthy-4\|Healthy / Virus stimulation, Condition and Cluster	CCNG2 BNIP3 BNIP3L HLA-DQB1 F12	3.57e-05	174	95	5	26544cc5f51cb4dc1251e62d9f80b6c956194d38
ToppCell	10x_5'_v1-Neoplastic-Stem-like-OPC-like\|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	FREM2 TTC28 HAPLN2 HAS3 TTPA	3.67e-05	175	95	5	cc596907ea1a64ab7b5a8c7d4ad12e6ee59bfed9
ToppCell	10x_5'_v1-Neoplastic-Stem-like\|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	FREM2 TTC28 HAPLN2 HAS3 TTPA	3.67e-05	175	95	5	a8400e7e47379901dcab5f2e364c3ff17765b4b9
ToppCell	10x_5'_v1-Neoplastic-Stem-like-OPC-like-OPC-like\|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	FREM2 TTC28 HAPLN2 HAS3 TTPA	3.67e-05	175	95	5	8a3abf40146ae3459d97cdf865c1c8f6b92ac639
ToppCell	10x_5'_v1-Neoplastic-Stem-like-OPC-like-OPC-like-Z\|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	FREM2 TTC28 HAPLN2 HAS3 TTPA	3.67e-05	175	95	5	378d2b79edac91fc74eee0fb42bb29dd9b07c36f
ToppCell	3'-Adult-LargeIntestine-Endothelial-lymphatic_endothelial-LEC3_(ADGRG3+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	RADIL HECW2 SLC16A11 F8 STAB1	3.77e-05	176	95	5	5d3b2395bb842eea39175f5af6a4c76527e2fc31
ToppCell	wk_15-18-Hematologic-Myeloid-Basophil\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	ACAP1 HK3 KBTBD11 TRPV2 F12	5.16e-05	188	95	5	3638d85452de15a060146628fbbad9d2a36feb13
ToppCell	CD8+_Memory_T_cell-RSV-5\|CD8+_Memory_T_cell / cell class, Virus stimulation and cluster	BNIP3 BNIP3L HLA-DQB1 HECW2 F12	5.70e-05	192	95	5	6357af0fb60a13a0ac727bc922b7606ab520ef5c
ToppCell	droplet-Liver-LIVER_HEP-30m-Endothelial\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TTC28 HECW2 ESAM F8 STAB1	5.84e-05	193	95	5	826b8dd801298b3e0cd76232feae5a14026b8806
ToppCell	343B-Myeloid-Macrophage-FABP4+_Macrophage_4\|343B / Donor, Lineage, Cell class and subclass (all cells)	HK3 OPN3 HLA-DQB1 VSIG4 TRPV2	5.84e-05	193	95	5	b9dcffd28ca309359fb110fb79de8ce066208ee1
ToppCell	droplet-Liver-LIVER_HEP-30m-Endothelial-endothelial_cell_of_hepatic_sinusoid\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TTC28 HECW2 ESAM F8 STAB1	5.84e-05	193	95	5	87d3a577d37fb0cb4b6313c596310de452bc3872
ToppCell	droplet-Liver-LIVER_HEP-30m-Endothelial-endothelial_cell_of_hepatic_sinusoid\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TTC28 HECW2 ESAM F8 STAB1	5.84e-05	193	95	5	d485634c564b268e344b6a2863c26f6adaec9e38
ToppCell	343B-Myeloid-Macrophage\|343B / Donor, Lineage, Cell class and subclass (all cells)	HK3 OPN3 HLA-DQB1 VSIG4 TRPV2	6.14e-05	195	95	5	48ba2044d2459c8b0d17bc7deca8d0195ac6a00e
ToppCell	3'-Parenchyma_lung-Endothelial-Blood_vessel_EC-capillary_endothelial_cell-EC_general_capillary-EC_general_capillary_L.2.0.2.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	PRPSAP1 HECW2 DUSP1 ESAM F8	6.14e-05	195	95	5	a08a3261679f89bb63ca2589d79b6deff716ccad
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-Mono-Mono_anti-infl\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	HK3 HLA-DQB1 DUSP1 VSIG4 STAB1	6.14e-05	195	95	5	0ec1b572bbb92b6da3440139366a4c1743b1ad92
ToppCell	wk_08-11-Hematologic-Myeloid-APOE+_Mac1\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	RPS6KA4 HLA-DQB1 VSIG4 TRPV2 F8	6.44e-05	197	95	5	121ec3f6d978de2f6c2cc397f7327d2e5587ab8b
ToppCell	Tracheal-10x5prime-Immune_Myeloid-Macrophage_other-Macro_CHIT1\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	CACNA2D4 HK3 HLA-DQB1 VSIG4 TRPV2	6.60e-05	198	95	5	9430ce7016b1a4724de036aab3e3e4082d24e436
ToppCell	proximal-Hematologic-Alveolar_Macrophage-3\|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	HK3 OPN3 HLA-DQB1 VSIG4 TRPV2	6.60e-05	198	95	5	a5deecd8809bc5b38ffda02143598ad0145e2559
ToppCell	COVID-19-COVID-19_Severe-Myeloid-pDC\|COVID-19_Severe / Disease, condition lineage and cell class	TTC24 RPS6KA4 OPN3 HLA-DQB1 KLHL33	6.60e-05	198	95	5	033ed362333e1d33f2aeea8da5865d2228d154dc
ToppCell	proximal-Hematologic-Alveolar_Macrophage\|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	HK3 OPN3 HLA-DQB1 VSIG4 TRPV2	6.60e-05	198	95	5	ec0092ef6207e788e2c20ddf007a2f6f6e351d0b
ToppCell	proximal-3-Hematologic-Alveolar_Macrophage\|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	HK3 OPN3 HLA-DQB1 VSIG4 TRPV2	6.60e-05	198	95	5	a5daf11bf7fe614be9f4a0fc6a4b37b5dce2f6fc
ToppCell	10x_3'_v2v3-Non-neoplastic-Myeloid-TAM-BDM-TAM-BDM_anti-infl-Z\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	NBEAL1 HLA-DQB1 DUSP1 VSIG4 STAB1	6.75e-05	199	95	5	e225c1bfc55947c30e7948be851daea04975efa5
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-Mono-Mono_hypoxia-F\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	CACNA2D4 ATP13A1 HLA-DQB1 VSIG4 STAB1	6.92e-05	200	95	5	88d713dfc792e7609bf7ecfb28f87cb748088570
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-TAM-BDM-TAM-BDM_hypoxia/MES-F\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	HK3 HLA-DQB1 BCKDK VSIG4 STAB1	6.92e-05	200	95	5	5f1de1f9305e1784c12d526f6c8bdd7d56229f9b
ToppCell	Tracheal-10x5prime-Immune_Myeloid-Macrophage_alveolar\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	HK3 OPN3 HLA-DQB1 VSIG4 TRPV2	6.92e-05	200	95	5	efdbd1273b07d9fe957380e347b5b6b45db0a271
ToppCell	Tracheal-10x5prime-Immune_Myeloid-Macrophage_alveolar-Macro_alveolar\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	HK3 OPN3 HLA-DQB1 VSIG4 TRPV2	6.92e-05	200	95	5	9ca86928fceaa1fefd0f9ffcfa5cc0a210ee5792
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-TAM-BDM-TAM-BDM_anti-infl-F\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	HK3 HLA-DQB1 DUSP1 VSIG4 STAB1	6.92e-05	200	95	5	74ceebee9af63f8b3ec5857eff1b662752bc3862
ToppCell	LPS-antiTNF-Epithelial_alveolar-Mes-Like-Differentiating_AT1\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	HMCN2 USP35 RFNG PIGO	1.63e-04	128	95	4	2cf0384240a4a663869cf6b27d954236f6214a9a
ToppCell	Hippocampus-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)-Nxph3\|Hippocampus / BrainAtlas - Mouse McCarroll V32	CWH43 OPN3 NKPD1 F12	2.17e-04	138	95	4	b63e26afafbd2cdeed9c9451e6f530ab6295504c
ToppCell	10x3'2.3-week_12-13-Myeloid_DC-DC-DC2\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	GABRB3 RPS6KA4 HLA-DQB1 KLHL33	2.30e-04	140	95	4	c3331cb7720f93af8bab35d02c6cbe87dd324d91
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c13-MKI67-CCL5_l\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	ACO2 DHCR7 BCKDK USP35	2.84e-04	148	95	4	6cd7ef4f29d9a0944f724d9d8117d4d25e517fe4
ToppCell	facs-Large_Intestine-Proximal-3m-Epithelial-Goblet_cell,_top_of_crypt_(Distal)\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ABCG4 NPHS2 TBKBP1 NLRP5	2.84e-04	148	95	4	dfd3f2c4b884ea9e23831a242a89ac985b409640
ToppCell	E17.5-Epithelial-airway_epithelial_cell-ciliated_cell_of_airway\|E17.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	NKPD1 LRP4 IRGQ TMEM125	2.99e-04	150	95	4	201d5b68e71c6c003285428be96c488e6d526edf
ToppCell	Hippocampus-Neuronal-Inhibitory-iN2(Gad1Gad2)-Tox\|Hippocampus / BrainAtlas - Mouse McCarroll V32	HMCN2 ACP4 KLHL33	3.46e-04	64	95	3	bf923a66b17e717b8d3817b9d0e201b82a7e4a88
ToppCell	Hippocampus-Neuronal-Inhibitory-iN2(Gad1Gad2)-Tox-Inhibitory_Gad1Gad2_Cplx3.Tox_(Interneuron,_lacunosum_oriens1?)\|Hippocampus / BrainAtlas - Mouse McCarroll V32	HMCN2 ACP4 KLHL33	3.46e-04	64	95	3	a3e852600c53b11175eb579e92962fa711f5678b
ToppCell	Hippocampus-Neuronal-Inhibitory-iN2(Gad1Gad2)-Tox-Inhibitory_Gad1Gad2_Cplx3.Tox_(Interneuron,_lacunosum_oriens1?)-\|Hippocampus / BrainAtlas - Mouse McCarroll V32	HMCN2 ACP4 KLHL33	3.46e-04	64	95	3	f8f43ad9354c786b418bac54614f96f50e8bea68
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-Degenerative_Endothelial_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	ACAP1 CLVS2 HAS3 TTPA	3.64e-04	158	95	4	0c3907e3395ed01b3fd7b75fdca6feadc890ea85
ToppCell	Control-Treg\|World / Disease group and Cell class	EPHB6 TLK1 HK3 KBTBD11	3.90e-04	161	95	4	ead9f5a491321f9e307f7c97e47a4ca124f59bb6
ToppCell	wk_20-22-Hematologic_Lymphocytic-T_&_ILC-T_entry\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	ACAP1 TTC24 SLC6A20 LYST	4.00e-04	162	95	4	a27750117e7f16a0bd07cc5f58a56becb39e800b
ToppCell	CD8+_Memory_T_cell-FLU-1\|CD8+_Memory_T_cell / cell class, Virus stimulation and cluster	BNIP3 BNIP3L HECW2 F8	4.00e-04	162	95	4	76f39935763848ea6e7917b2f9f1432c543063d9
ToppCell	Bronchial_Biopsy-Endothelial-Lymphatic\|Endothelial / Tissue, Lineage and Cell class of Lung Cells from 10X	GABRB3 RADIL KBTBD11 TMEM125	4.09e-04	163	95	4	961c3a1303108afd680365466045f3460a30a7b0
ToppCell	E12.5-Endothelial-lymphatic_endothelial_cell-endothelial_cell_of_lymphatic_vessel\|E12.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	KBTBD11 GNAS SIPA1 STAB1	4.09e-04	163	95	4	c21114826bee1b05b411984326fef6b6e0d05316
ToppCell	E12.5-Endothelial-lymphatic_endothelial_cell\|E12.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	KBTBD11 GNAS SIPA1 STAB1	4.09e-04	163	95	4	5d49414432db259a19df50d7944581d00b69f537
ToppCell	droplet-Marrow-nan-3m-Lymphocytic-immature_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	BNIP3L DUSP1 LYST F8	4.19e-04	164	95	4	f9a2cc12179d5621c9174ec01d7418a71edd28d1
ToppCell	343B-Myeloid-Macrophage-FABP4+_Macrophage_proliferating_2\|343B / Donor, Lineage, Cell class and subclass (all cells)	HK3 OPN3 RAD54B F12	4.48e-04	167	95	4	7efa0081e79f22b219eac64ffcaedb2179cde299
ToppCell	tumor_Lymph_Node_/_Brain-T/NK_cells-CD8+/CD4+_Mixed_Th\|tumor_Lymph_Node_/_Brain / Location, Cell class and cell subclass	EPHB6 ACAP1 TRBV6-5 SLC16A11	4.48e-04	167	95	4	c0c944eae0514dc8e00d0c2892a0792e157695ec
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid-Macrophage_Dendritic-M2_Macrophage\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	HK3 HLA-DQB1 VSIG4 STAB1	4.58e-04	168	95	4	61a5435b27b01ff1a509ea463a6af220c5d2c9b3
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid-Macrophage_Dendritic\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	HK3 HLA-DQB1 VSIG4 STAB1	4.58e-04	168	95	4	26fce414439ccd204e3acb41f2b4f75072df5a26
ToppCell	droplet-Kidney-nan-18m-Epithelial-Pecam____kidney_capillary_endothelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	B3GALT2 NPHS2 HECW2 F8	4.69e-04	169	95	4	87116c33c5ca8cb1862e103e5607b1df4d264569
ToppCell	5'-Parenchyma_lung-Immune_Myeloid-Dendritic-plasmacytoid_dendritic_cell-Plasmacytoid_DCs\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	TTC24 OPN3 OR2C3 KLHL33	4.79e-04	170	95	4	92e765ae0d3adb38d3b22fddb873fd5ccad3fd44
ToppCell	5'-Parenchyma_lung-Immune_Myeloid-Dendritic-plasmacytoid_dendritic_cell\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	TTC24 OPN3 OR2C3 KLHL33	4.79e-04	170	95	4	9f8b215caa1afa3cd7104c06fca7cfd790640f66
ToppCell	droplet-Heart-HEART_(LV+RV_ONLY)-30m-Myeloid-coronary_vascular_endothelial_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ACAP1 GAK HK3 SLC16A11	4.79e-04	170	95	4	f3d5678669dcaed1836014cea543758b7ccc6b46
ToppCell	facs-Liver-Non-hepatocytes-3m-Epithelial-nan\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	BNIP3 HAPLN2 ACAA2 TTPA	5.01e-04	172	95	4	feaaf8ca7983d04a59ed0a7b3fb0e6d4b3a055f2
ToppCell	facs-Liver-Non-hepatocytes-3m-Epithelial\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	BNIP3 HAPLN2 ACAA2 TTPA	5.01e-04	172	95	4	9adfb4a65669cc536343616637058d0a4728013f
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid-Monocytic-Monocyte-derived_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	CACNA2D4 HLA-DQB1 VSIG4 NLRP5	5.01e-04	172	95	4	72fbfa890995e47048b47199c170cc7dcd7661f8
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid-Monocytic\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	CACNA2D4 HLA-DQB1 VSIG4 NLRP5	5.01e-04	172	95	4	2ca6f0d1181aabe0d0e3e8f2e193f08dbda42dea
ToppCell	facs-Liver-Non-hepatocytes-3m-Epithelial-hepatocyte\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	BNIP3 HAPLN2 ACAA2 TTPA	5.01e-04	172	95	4	8aed9c113f27d00401c272a3684495a4bc75bd0f
ToppCell	droplet-Kidney-nan-3m-Epithelial-Pecam____kidney_capillary_endothelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GABRB1 B3GALT2 NPHS2 HECW2	5.01e-04	172	95	4	073a503dc922e3e3ac3528e249b0f8b74402110b
ToppCell	normal_Pleural_Fluid-Myeloid_cells-CD1c+_DCs\|normal_Pleural_Fluid / Location, Cell class and cell subclass	CCNG2 ABCG4 RPS6KA4 HLA-DQB1	5.01e-04	172	95	4	200b2e63313b110b8ca59ee5b72c02cc8ed907cd
ToppCell	5'-GW_trimst-1.5-SmallIntestine-Epithelial-neuro-epithelial-I_cells_(CCK+)\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	GIPR NPHS2 TTC24 ADGRG4	5.01e-04	172	95	4	2651dece87c3e3d2d6370f5274ebae357474b825
ToppCell	3'-Pediatric_IBD-SmallIntestine-Endothelial-lymphatic_endothelial-LEC4_(STAB2+)\|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract	PRPSAP1 KBTBD11 SLC16A11 F8	5.01e-04	172	95	4	1bad7b19724e1b53ace7e05644215334c9f43910
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Lymphoid-CD4/CD8-CD4_rest-A\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	ACAP1 ATP13A1 TRPV2 USP35	5.12e-04	173	95	4	1bf9c91c1803a540b5e43bc4280aab4289341cee
ToppCell	Severe-B_naive-8\|Severe / disease group and sub_cluster of B and Plasma cells(res = 0.5)	OPN3 HLA-DQB1 DUSP1 LYST	5.23e-04	174	95	4	f3f8c924420f46321bd47e2b97f18c7241541599
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Ascending_Vasa_Recta_Endothelial_Cell_prolif\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	HECW2 TRPV2 ESAM F8	5.34e-04	175	95	4	90302e8a44858ef3b2a165b88284d4788d591a99
ToppCell	droplet-Kidney-nan-18m-Endothelial-kidney_capillary_endothelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NPHS2 HECW2 ESAM F8	5.46e-04	176	95	4	5386386619cf173939d3c117b20e6f27ab397993
ToppCell	facs-Lung-Endomucin-24m-Endothelial-endothelial_cell_of_lymphatic_vessel\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KBTBD11 HAS3 F8 STAB1	5.46e-04	176	95	4	057d2759fdc67176c25802b57a78064d8cc93205
ToppCell	facs-Lung-Endomucin-24m-Endothelial-Lymphatic_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KBTBD11 HAS3 F8 STAB1	5.46e-04	176	95	4	b81e5d23b31cefc8d374ef403e21acc390c14a80
ToppCell	droplet-Kidney-nan-18m-Endothelial-Pecam____kidney_capillary_endothelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NPHS2 HECW2 ESAM F8	5.46e-04	176	95	4	820edade963768e4bfd86b554da4cd7100567ac8
ToppCell	facs-Large_Intestine-Proximal-3m-Epithelial-nan\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRPSAP1 CWH43 KBTBD11 FBXL5	5.46e-04	176	95	4	1dd54bfaa58541de51e5a8328651d390833bd480
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Glomerular_Capillary_Endothelial_Cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	HMCN2 HECW2 ESAM F8	5.46e-04	176	95	4	64e426f5e84884ce2c29acf6f4b958962a63927f
ToppCell	droplet-Large_Intestine-COLON_PROXIMAL-30m-Hematologic-hematopoietic_stem_cell\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EPHB6 ACAP1 TTC28 F12	5.70e-04	178	95	4	d9eba884e18a0c89bdc70c194bfe4d62cca164fa
ToppCell	droplet-Large_Intestine-COLON_PROXIMAL-30m-Hematologic-hematopoietic_stem_cell\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EPHB6 ACAP1 TTC28 F12	5.70e-04	178	95	4	b03aa1de9d20895ebad55f6fcd6fe7a49335db5a
ToppCell	droplet-Large_Intestine-COLON_PROXIMAL-30m-Hematologic\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EPHB6 ACAP1 TTC28 F12	5.70e-04	178	95	4	0f5cf34609df791c8baebfdc6590f6eb4dbe0509
ToppCell	tumor_Lymph_Node_/_Brain-Myeloid_cells-Activated_DCs\|tumor_Lymph_Node_/_Brain / Location, Cell class and cell subclass	OPN3 HLA-DQB1 ACO2 PIGO	5.94e-04	180	95	4	aae85fb3c92a45614616a3ee3a1af5244cc299a7
ToppCell	3'-Pediatric_IBD-SmallIntestine-Endothelial-lymphatic_endothelial-LEC6_(ADAMTS4+)\|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract	GABRB3 KBTBD11 OR2C3 SLC16A11	5.94e-04	180	95	4	25f8e82bbc1853cb7d072484e99369c72779dd1e
ToppCell	droplet-Liver-nan-3m-Endothelial-nan\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TTC28 ESAM F8 STAB1	6.06e-04	181	95	4	fcc94f04dae98b817ec06b282d2e887804d37ae5
ToppCell	5'-Parenchyma_lung-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophage_CCL3+-Alveolar_macrophage_CCL3+_L.1.0.2.2\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	HLA-DQB1 BCKDK VSIG4 OR2C3	6.06e-04	181	95	4	a8d4b2340d99734bf9379b467fb481c598b9b4fb
ToppCell	droplet-Liver-nan-3m-Endothelial-endothelial_cell_of_hepatic_sinusoid\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HECW2 ESAM F8 STAB1	6.06e-04	181	95	4	a53f05c4c47465ee62e353716456bd09ab464b23
ToppCell	droplet-Mammary_Gland-nan-18m-Endothelial-nan\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ESAM F8 PRRT4 STAB1	6.06e-04	181	95	4	2e15c46e8260bb04d8264478c19a707221996026
ToppCell	10x_3'_v2v3-Non-neoplastic-Myeloid-TAM-BDM-TAM-BDM_MHC-B\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	HLA-DQB1 DUSP1 SIPA1 STAB1	6.19e-04	182	95	4	16186b7a0c33caa48631962381e3ab7e5d166163
ToppCell	tumor_Lymph_Node_/_Brain-Myeloid_cells-Alveolar_Mac\|Myeloid_cells / Location, Cell class and cell subclass	HK3 HLA-DQB1 VSIG4 TRPV2	6.19e-04	182	95	4	a035d45fd512bee8dac38eb387dbf39f5a8a1fed
ToppCell	droplet-Kidney-nan-3m-Endothelial-Pecam____kidney_capillary_endothelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RTL1 HECW2 ESAM F8	6.19e-04	182	95	4	f4a5f1c3a04c0566eb96607dab7a0d9a5ebc3fd1
ToppCell	systemic_lupus_erythematosus-flare-Lymphocytic_T-T8_naive-male\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	ACAP1 TTC24 NBEAL1 PRRT4	6.19e-04	182	95	4	3a3ed195c15d33d46a2f395cb93018e4bba28353
ToppCell	3'-Pediatric_IBD-SmallIntestine-Hematopoietic-T_cells-Th17\|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract	B3GALT2 ACAP1 CACNA2D4 DUSP1	6.32e-04	183	95	4	1ee09af56dac121c841d869021ca625dd3336b84
ToppCell	droplet-Liver-nan-3m-Endothelial-endothelial_cell_of_hepatic_sinusoid\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HECW2 ESAM F8 STAB1	6.32e-04	183	95	4	709a486154b3157427deb3b8886b63ac39ea42dd
ToppCell	droplet-Liver-nan-3m-Endothelial\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HECW2 ESAM F8 STAB1	6.32e-04	183	95	4	dc06f19f6f80f4c7f13f1f990c1fe0f91ba64ea7
ToppCell	droplet-Kidney-nan-18m-Epithelial-kidney_loop_of_Henle_ascending_limb_epithelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CWH43 CLVS2 ACO2 ESAM	6.32e-04	183	95	4	03c7e69136d5a3b9c5b2c91733e9b1c791f45c49
ToppCell	mild-Myeloid-mDC\|mild / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs	GIPR OPN3 HLA-DQB1 VSIG4	6.45e-04	184	95	4	8b37c00d59d9992d3b43268991da7bb94646c70e
ToppCell	5'-GW_trimst-1-SmallIntestine-Endothelial-blood_vessel_EC-venous_capillary\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CMTM2 OR2C3 ESAM STAB1	6.45e-04	184	95	4	97e97de52daaff8840f4ee76a94ba5e3f79de7ce
ToppCell	10x_3'_v2v3-Non-neoplastic-Myeloid-TAM-BDM-TAM-BDM_hypoxia/MES-A\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	CACNA2D4 BNIP3 HK3 STAB1	6.45e-04	184	95	4	a902109b04a94770f5f6db5ddc372049f2921d38
ToppCell	PCW_05-06-Epithelial-Epithelial_alveolar-distal-epi_SOX9^high_Etv5^high_distal_(10)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	FREM2 HAS3 VWA2 TTPA	6.45e-04	184	95	4	fa4915b0498f3069fd5ef497286445528f75187e
ToppCell	droplet-Lung-nan-3m-Endothelial-endothelial_cell_of_lymphatic_vessel\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KBTBD11 TTPA PRRT4 STAB1	6.58e-04	185	95	4	6a85399cfdb9b89683c874e7f046957f9a601dc2
ToppCell	droplet-Lung-nan-3m-Endothelial-Lymphatic_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KBTBD11 TTPA PRRT4 STAB1	6.58e-04	185	95	4	64791056cdbb739136dbef08f4b16e2b5427faad
Disease	chronic hepatitis C virus infection	CWH43 HLA-DQB1 AK9	1.45e-04	33	91	3	EFO_0004220
Disease	X-11315 measurement	SLC6A20 PYCR3	5.08e-04	11	91	2	EFO_0021223
Disease	hyperhomocysteinemia (implicated_via_orthology)	F8 F12	5.08e-04	11	91	2	DOID:9279 (implicated_via_orthology)
Disease	Respiratory Distress Syndrome, Adult	GABRB1 ACO2 ACAA2	6.63e-04	55	91	3	C0035222
Disease	obsolete_red blood cell distribution width	PRPSAP1 BNIP3L TBKBP1 TTC28 HECW2 DUSP1 MORF4L1 ACAA2 AK9 SIPA1 F8 PYCR3	8.78e-04	1347	91	12	EFO_0005192
Disease	gastroparesis	HLA-DQB1 MESP2	1.10e-03	16	91	2	EFO_1000948
Disease	Congenital Myasthenic Syndromes, Postsynaptic	LRP4 AK9	1.24e-03	17	91	2	C0751883
Disease	Tachycardia	GNAS RYR2	1.39e-03	18	91	2	C0039231
Disease	Tachyarrhythmia	GNAS RYR2	1.39e-03	18	91	2	C0080203
Disease	Headache, HbA1c measurement	GIPR NBEAL1	1.90e-03	21	91	2	EFO_0004541, HP_0002315
Disease	L lactate dehydrogenase measurement	HLA-DQB1 STAB1	2.91e-03	26	91	2	EFO_0004808

Protein segments in the cluster

Peptide	Gene	Start	Entry
GYAQILRDLGGIVLA	ACO2	431	Q99798
VIGVLIGLLYLHIGD	ABCG4	401	Q9H172
RGAGFLALLHLLYLV	ELMOD3	211	Q96FG2
LHLGALPYAVGKLGL	CPSF2	66	Q9P2I0
GLAGDHQQLILYRLG	ADGRG4	91	Q8IZF6
EGARVLALGYKELGH	ATP13A1	681	Q9HD20
GHEGVQLLGLLNVYL	CCNG2	11	Q16589
VEGVYLHSLLVLVGG	GIPR	236	P48546
LGTGLLESGRHYLAA	ACAP1	41	Q15027
HAVGVLLLGLVGYYI	DHCR7	336	Q9UBM7
GIGTDVYLRLRHIDG	BCKDK	391	O14874
QHIRLREVGYSGLGL	NBEAL1	1176	Q6ZS30
GLNLIGGSHLILYDI	RAD54B	726	Q9Y620
GYIVEGLLGARLLHS	RFNG	241	Q9Y644
VYGAPHLLRLFVRIG	MORF4L1	296	Q9UBU8
GLGYLRAVDLIRHGG	RADIL	1036	Q96JH8
GRILGLALIHQYLLD	HECW2	1311	Q9P2P5
GYDPGGRHLLLFIII	PCDHA7	6	Q9UN72
NGIILGLIYLDSRLH	OR2A12	41	Q8NGT7
AVLQGELLVLGGYSH	KLHL33	461	A6NCF5
SDLLHLYLGLGLLAG	SLC16A11	126	Q8NCK7
TLILITNGLHARGYG	HAPLN2	81	Q9GZV7
AGLQHVSAVGRLLYL	HMCN2	2216	Q8NDA2
LLLRHGADAGALDYG	ASB18	311	Q6ZVZ8
RLAIRYIGHLSAVLG	MESP2	126	Q0VG99
LSGLGALPRYGELLH	FREM2	221	Q5SZK8
RIIHGGLAERSGLLY	MPP4	181	Q96JB8
YERVIIFRLGHLLPG	NPHS2	131	Q9NP85
IRLHPDGTVLYGLRI	GABRB1	141	P18505
IRLHPDGTVLYGLRI	GABRB3	141	P28472
LYRGELNEHLGLLGP	F8	1766	P00451
QLHTYLVLELLRGGE	RPS6KA4	476	O75676
YLLVRGISGEQRIHL	NLRP5	426	P59047
HAGLGRTGVLIACYL	PTPDC1	191	A2A3K4
PLGLILVSYGHIARA	OR2C3	211	Q8N628
YALGVGLLHIVLLSI	ORMDL1	26	Q9P0S3
GGLYLGELVRLVLAH	HK3	311	P52790
TLLALQGALGLYDGH	ACP4	291	Q9BZG2
YERLALLLGSIGLLG	OPN3	41	Q9H1Y3
SLGIRRLHLEDVYVG	B3GALT2	331	O43825
LIVIYHARSTLGGRL	GAK	641	O14976
GLIFLGLGLIIHHRS	HLA-DQB1	241	P01920
LSHLLAIGLGIYIGR	BNIP3	171	Q12983
LRGRLLAGAYHAVVL	DUSP1	71	P28562
VLSRGHGEYILLGNT	CACNA2D4	651	Q7Z3S7
SHVLALGLGIYIGKR	BNIP3L	196	O60238
VYRATHRLLLLGAGE	GNAS	36	P63092
LGLLAGLVLLYHRRG	ESAM	261	Q96AP7
TLGQYLVHGRGFLLL	LYST	41	Q99698
SYAERLRLGLAVIHG	PRPSAP1	186	Q14558
GLYGAILGLHLLIQS	HAS3	46	O00219
LRVLTLGGGLPYLEH	FBXL5	616	Q9UKA1
YGAGIVLRLGNIARL	SAMM50	426	Q9Y512
PLLGYLARVQLLGHI	SLC38A9	456	Q8NBW4
LARVQLLGHIFGDIY	SLC38A9	461	Q8NBW4
GYLIGGDVLRLLHGH	RYR2	226	Q92736
VLLHRQYDGIGGLVR	RYR2	2086	Q92736
GLGYRAAHGVLLQAL	IRGQ	591	Q8WZA9
LICGDRATGLHYGII	NR6A1	61	Q15406
VGVGLLGLGLRHKAY	CWH43	401	Q9H720
GLVALRGAHPYIAAL	F12	376	P00748
AYRGGHLTIRLALGG	MRPS16	11	Q9Y3D3
LRVGYVINHLSGLAL	RTL1	236	A6NKG5
GLKHLSIGGALRYVL	AK9	1436	Q5TCS8
YGGRGLLNVSRIIVH	PRSS29P	136	A6NIE9
SLLGGLIYGHLSDRV	SLC22A24	156	Q8N4F4
LGVGLLYLSLGGHAL	NKPD1	131	Q17RQ9
LVGGLRAHVPYILEV	EPHB6	446	O15197
QLDLYHGRGEAITLR	SIPA1	646	Q96FS4
RLLALDGHLYAVGGE	KBTBD11	406	O94819
TIYGLHALEQGGLRA	PYCR3	241	Q53H96
VLIIYLIRGLTLHGA	SLC6A20	206	Q9NP91
RYLLLHLLGRGGFSE	TLK2	461	Q86UE8
LHYLLAVILIGAAGV	CMTM2	176	Q8TAZ6
GGLANLDHYGRKILV	CLVS2	106	Q5SYC1
AIYLARHVGLRVGIP	ACAA2	66	P42765
YLLLHLLGRGGFSEV	TLK1	456	Q9UKI8
ERRLLGHLYNDLGLG	TTC24	231	A2A3L6
LLALGARLYVGGAEE	USP35	41	Q9P2H5
MLLTGHILILLGGIY	TRPV2	431	Q9Y5S1
HILILLGGIYLLVGQ	TRPV2	436	Q9Y5S1
ELALKYLLHRGLPGG	VWA2	131	Q5GFL6
HVYGVGALFGLVALL	PRRT4	366	C9JH25
AGALLGLVAGALYLR	STAB1	2486	Q9NY15
GLLLLGHLTVDTYGR	VSIG4	6	Q9Y279
LLYGLHEGKRLGPLS	TNXA	111	Q16473
SIIGLLKAGYHGVLR	TTPA	91	P49638
HLVGRGYRGLGVSAL	WDR6	326	Q9NNW5
LGTVMHRVIGLGLLY	TMEM87B	316	Q96K49
HRVIGLGLLYLIFAA	TMEM87B	321	Q96K49
GRHRQLILVLEGELY	TTC28	1416	Q96AY4
IGELHILGVVYNLGT	TRAPPC8	831	Q9Y2L5
HNGAYALRLGIGLLL	PIGO	616	Q8TEQ8
THGLLGIYQELLGLA	THOP1	366	P52888
LDLHYLALRGGSGLS	TBKBP1	196	A7MCY6
LLLGLLLYQVGVSGH	TMEM125	161	Q96AQ2
GLRLIHYSVGAGITD	TRBV6-5	61	A0A0K0K1A5
LRHGLIPNLLGEGIY	AGL	1131	P35573
GLHISYAIGGLLSIL	LRP4	1721	O75096