Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionnucleoside-triphosphatase regulator activity

DOCK5 ARFGEF3 TBC1D30 TRIO SRGAP3 SGSM2 SRGAP1 RAPGEF1 DENND5A HERC1

3.44e-075074910GO:0060589
GeneOntologyMolecularFunctionGTPase regulator activity

DOCK5 ARFGEF3 TBC1D30 TRIO SRGAP3 SGSM2 SRGAP1 RAPGEF1 DENND5A HERC1

3.44e-075074910GO:0030695
GeneOntologyMolecularFunctionenzyme regulator activity

TAOK2 PRKAG3 DOCK5 ARFGEF3 TAOK3 TBC1D30 TRIO SRGAP3 SGSM2 SRGAP1 RAPGEF1 BIRC3 TAOK1 DENND5A HERC1

8.61e-0714184915GO:0030234
GeneOntologyMolecularFunctionguanyl-nucleotide exchange factor activity

DOCK5 ARFGEF3 TRIO RAPGEF1 DENND5A HERC1

2.07e-05231496GO:0005085
GeneOntologyMolecularFunctionsmall GTPase binding

DOCK5 TBC1D30 SGSM2 SRGAP1 MFN2 DENND5A

1.29e-04321496GO:0031267
GeneOntologyMolecularFunctiontau protein binding

TAOK2 HDAC6 TAOK1

1.96e-0446493GO:0048156
GeneOntologyMolecularFunctionGTPase binding

DOCK5 TBC1D30 SGSM2 SRGAP1 MFN2 DENND5A

2.39e-04360496GO:0051020
GeneOntologyMolecularFunctionGTPase activator activity

DOCK5 TBC1D30 SRGAP3 SGSM2 SRGAP1

5.93e-04279495GO:0005096
GeneOntologyMolecularFunctionprotein serine/threonine kinase activity

TAOK2 PRKAG3 BMPR1B TAOK3 TRIO TAOK1

7.45e-04446496GO:0004674
GeneOntologyMolecularFunctionenzyme activator activity

TAOK2 DOCK5 TBC1D30 SRGAP3 SGSM2 SRGAP1 TAOK1

1.04e-03656497GO:0008047
GeneOntologyMolecularFunctionhydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides

HDAC6 MIER3 PGLYRP2

1.04e-0381493GO:0016811
GeneOntologyMolecularFunctiontau-protein kinase activity

TAOK2 TAOK1

1.32e-0322492GO:0050321
GeneOntologyMolecularFunctionhistone deacetylase activity

HDAC6 MIER3

1.57e-0324492GO:0004407
GeneOntologyMolecularFunctionprotein lysine deacetylase activity

HDAC6 MIER3

1.71e-0325492GO:0033558
GeneOntologyMolecularFunctionbeta-catenin binding

HDAC6 PTPRK CHD8

3.19e-03120493GO:0008013
GeneOntologyMolecularFunctionprotein kinase activity

TAOK2 PRKAG3 BMPR1B TAOK3 TRIO TAOK1

3.35e-03600496GO:0004672
GeneOntologyMolecularFunctionprotein kinase regulator activity

TAOK2 PRKAG3 TAOK3 TAOK1

3.71e-03259494GO:0019887
GeneOntologyMolecularFunctionmicrofilament motor activity

MYO1H MYO5C

3.92e-0338492GO:0000146
GeneOntologyMolecularFunctiondeacetylase activity

HDAC6 MIER3

4.34e-0340492GO:0019213
GeneOntologyMolecularFunctionhydrolase activity, acting on carbon-nitrogen (but not peptide) bonds

HDAC6 MIER3 PGLYRP2

5.52e-03146493GO:0016810
GeneOntologyMolecularFunctionbeta-tubulin binding

HDAC6 TAOK1

6.45e-0349492GO:0048487
GeneOntologyMolecularFunctionkinase regulator activity

TAOK2 PRKAG3 TAOK3 TAOK1

6.59e-03305494GO:0019207
GeneOntologyBiologicalProcesspositive regulation of stress-activated protein kinase signaling cascade

TAOK2 TAOK3 TAOK1

4.47e-0526553GO:0070304
GeneOntologyBiologicalProcesspositive regulation of stress-activated MAPK cascade

TAOK2 TAOK3 TAOK1

4.47e-0526553GO:0032874
GeneOntologyCellularComponentreceptor complex

TAOK2 BMPR1B TRBV6-9 TRBV6-8 TRBV6-7 TRBV6-6 TRBV6-3 PLXNA4 ITPR2

1.89e-05581559GO:0043235
GeneOntologyCellularComponentT cell receptor complex

TRBV6-9 TRBV6-8 TRBV6-7 TRBV6-6 TRBV6-3

6.88e-05163555GO:0042101
GeneOntologyCellularComponentplasma membrane signaling receptor complex

BMPR1B TRBV6-9 TRBV6-8 TRBV6-7 TRBV6-6 TRBV6-3

3.07e-04350556GO:0098802
DomainSH3_1

DOCK5 TRIO SRGAP3 SRGAP1

8.25e-04164484PF00018
DomainRUN

SGSM2 DENND5A

9.64e-0418482SM00593
DomainRUN

SGSM2 DENND5A

1.08e-0319482PS50826
DomainRUN

SGSM2 DENND5A

1.08e-0319482PF02759
DomainRun_dom

SGSM2 DENND5A

1.08e-0319482IPR004012
DomainFCH

SRGAP3 SRGAP1

1.45e-0322482PF00611
DomainReg_chr_condens

MARVELD1 HERC1

1.45e-0322482IPR000408
DomainFCH

SRGAP3 SRGAP1

1.45e-0322482SM00055
DomainRho_GTPase_activation_prot

SRGAP3 SRGAP1 PLXNA4

1.50e-0388483IPR008936
DomainFCH_dom

SRGAP3 SRGAP1

1.58e-0323482IPR001060
DomainF_BAR

SRGAP3 SRGAP1

1.87e-0325482IPR031160
DomainF_BAR

SRGAP3 SRGAP1

1.87e-0325482PS51741
DomainSer/Thr_kinase_AS

TAOK2 BMPR1B TAOK3 TRIO TAOK1

2.16e-03357485IPR008271
DomainS_TKc

TAOK2 BMPR1B TAOK3 TRIO TAOK1

2.22e-03359485SM00220
DomainSH3

DOCK5 TRIO SRGAP3 SRGAP1

2.27e-03216484SM00326
DomainSH3

DOCK5 TRIO SRGAP3 SRGAP1

2.27e-03216484PS50002
DomainPROTEIN_KINASE_ST

TAOK2 BMPR1B TAOK3 TRIO TAOK1

2.30e-03362485PS00108
DomainSH3_domain

DOCK5 TRIO SRGAP3 SRGAP1

2.43e-03220484IPR001452
DomainPkinase

TAOK2 BMPR1B TAOK3 TRIO TAOK1

2.87e-03381485PF00069
DomainMyb_DNA-binding

MIER3 MYBL1

3.65e-0335482PF00249
DomainPROTEIN_KINASE_ATP

TAOK2 BMPR1B TAOK3 TRIO TAOK1

6.30e-03459485PS00107
DomainTBC

TBC1D30 SGSM2

7.04e-0349482SM00164
DomainSANT

MIER3 MYBL1

7.32e-0350482SM00717
DomainSANT/Myb

MIER3 MYBL1

7.90e-0352482IPR001005
DomainProt_kinase_dom

TAOK2 BMPR1B TAOK3 TRIO TAOK1

8.18e-03489485IPR000719
DomainRabGAP-TBC

TBC1D30 SGSM2

8.20e-0353482PF00566
DomainPROTEIN_KINASE_DOM

TAOK2 BMPR1B TAOK3 TRIO TAOK1

8.45e-03493485PS50011
DomainTBC_RABGAP

TBC1D30 SGSM2

8.81e-0355482PS50086
DomainRab-GTPase-TBC_dom

TBC1D30 SGSM2

8.81e-0355482IPR000195
PathwayPID_P38_MKK3_6PATHWAY

TAOK2 TAOK3 TAOK1

3.51e-0526353M20
PathwayREACTOME_RAC1_GTPASE_CYCLE

DOCK5 TAOK3 TRIO SRGAP3 SRGAP1

6.68e-05175355MM15599
PathwayREACTOME_RAC1_GTPASE_CYCLE

DOCK5 TAOK3 TRIO SRGAP3 SRGAP1

8.48e-05184355M41809
PathwayREACTOME_SIGNALING_BY_RHO_GTPASES_MIRO_GTPASES_AND_RHOBTB3

DOCK5 TAOK3 TRIO SRGAP3 SRGAP1 MFN2 RAPGEF1 TAOK1

1.51e-04649358MM15690
PathwayREACTOME_INACTIVATION_OF_CDC42_AND_RAC1

SRGAP3 SRGAP1

1.66e-048352M27349
PathwayREACTOME_SIGNALING_BY_RHO_GTPASES_MIRO_GTPASES_AND_RHOBTB3

DOCK5 TAOK3 TRIO SRGAP3 SRGAP1 MFN2 RAPGEF1 TAOK1

3.06e-04720358M41838
Pubmed

TAO kinases mediate activation of p38 in response to DNA damage.

TAOK2 TAOK3 TAOK1

3.95e-09356317396146
Pubmed

The complete 685-kilobase DNA sequence of the human beta T cell receptor locus.

TRBV6-9 TRBV6-8 TRBV6-7 TRBV6-6 TRBV6-3 TRBV6-2

1.03e-08955668650574
Pubmed

Comparative studies of a new subfamily of human Ste20-like kinases: homodimerization, subcellular localization, and selective activation of MKK3 and p38.

TAOK2 TAOK3 TAOK1

3.94e-08556313679851
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

TAOK2 MARVELD1 BCL2L11 TRIO SGSM2 MFN2 RAPGEF1 CHD8 DENND5A MLLT10 HERC1 ITPR2

1.53e-071105561235748872
Pubmed

Slit-Robo GTPase-activating proteins are differentially expressed in murine dorsal root ganglia: modulation by peripheral nerve injury.

SRGAP3 SRGAP1

2.55e-06256222271578
Pubmed

Targeting TAO Kinases Using a New Inhibitor Compound Delays Mitosis and Induces Mitotic Cell Death in Centrosome Amplified Breast Cancer Cells.

TAOK2 TAOK1

2.55e-06256228830982
Pubmed

Isolation of TAO1, a protein kinase that activates MEKs in stress-activated protein kinase cascades.

TAOK2 TAOK1

7.63e-0635629786855
Pubmed

HDAC6 maintains mitochondrial connectivity under hypoxic stress by suppressing MARCH5/MITOL dependent MFN2 degradation.

HDAC6 MFN2

7.63e-06356226210454
Pubmed

Dynamic expression of the Slit-Robo GTPase activating protein genes during development of the murine nervous system.

SRGAP3 SRGAP1

7.63e-06356219137586
Pubmed

Prostate-derived sterile 20-like kinases (PSKs/TAOKs) phosphorylate tau protein and are activated in tangle-bearing neurons in Alzheimer disease.

TAOK2 TAOK1

7.63e-06356223585562
Pubmed

Isolation of the protein kinase TAO2 and identification of its mitogen-activated protein kinase/extracellular signal-regulated kinase kinase binding domain.

TAOK2 TAOK1

1.52e-05456210497253
Pubmed

Autism spectrum disorder susceptibility gene TAOK2 affects basal dendrite formation in the neocortex.

TAOK2 TAOK1

2.54e-05556222683681
Pubmed

Roles of tau protein in health and disease.

TAOK2 HDAC6 TAOK1

3.74e-054056328386764
Pubmed

Context-specific regulation of cell survival by a miRNA-controlled BIM rheostat.

BMPR1B BCL2L11

3.80e-05656231699777
Pubmed

SRGAP1 Controls Small Rho GTPases To Regulate Podocyte Foot Process Maintenance.

SRGAP3 SRGAP1

3.80e-05656233514561
Pubmed

The prostate-derived sterile 20-like kinase (PSK) regulates microtubule organization and stability.

TAOK2 TAOK1

3.80e-05656212639963
Pubmed

FNBP2 gene on human chromosome 1q32.1 encodes ARHGAP family protein with FCH, FBH, RhoGAP and SH3 domains.

SRGAP3 SRGAP1

3.80e-05656212736724
Pubmed

Signal transduction in neuronal migration: roles of GTPase activating proteins and the small GTPase Cdc42 in the Slit-Robo pathway.

SRGAP3 SRGAP1

3.80e-05656211672528
Pubmed

Osmotic stress activates the TAK1-JNK pathway while blocking TAK1-mediated NF-kappaB activation: TAO2 regulates TAK1 pathways.

TAOK2 TAOK1

3.80e-05656216893890
Pubmed

Evidence for a role of srGAP3 in the positioning of commissural axons within the ventrolateral funiculus of the mouse spinal cord.

SRGAP3 SRGAP1

5.32e-05756221655271
Pubmed

Genome-wide association studies suggest sex-specific loci associated with abdominal and visceral fat.

MLLT10 BBS9

5.32e-05756226480920
Pubmed

A BBSome subunit links ciliogenesis, microtubule stability, and acetylation.

HDAC6 BBS9

1.14e-041056219081074
Pubmed

Signal transduction protein array analysis links LRRK2 to Ste20 kinases and PKC zeta that modulate neuronal plasticity.

TAOK3 TAOK1

1.14e-041056220949042
Pubmed

The genomic structure of human V beta 6 T cell antigen receptor genes.

TRBV6-9 TRBV6-2

1.39e-04115621660526
Pubmed

M1AP interacts with the mammalian ZZS complex and promotes male meiotic recombination.

M1AP BIRC3

1.96e-041356236440627
Pubmed

Mayo Genome Consortia: a genotype-phenotype resource for genome-wide association studies with an application to the analysis of circulating bilirubin levels.

UGT1A3 MROH2A

2.29e-041456221646302
Pubmed

The conserved RNA helicase YTHDC2 regulates the transition from proliferation to differentiation in the germline.

MEIOC MYBL1

2.64e-041556229087293
Pubmed

Excitatory neuronal CHD8 in the regulation of neocortical development and sensory-motor behaviors.

GAD2 CHD8

3.01e-041656233626347
Pubmed

Calcium handling precedes cardiac differentiation to initiate the first heartbeat.

CACNA1D ITPR2

3.41e-041756227725084
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

ARFGEF3 SRGAP3 SGSM2 MFN2 URB2

5.01e-0440756512693553
Pubmed

HAND1 loss-of-function within the embryonic myocardium reveals survivable congenital cardiac defects and adult heart failure.

CACNA1D ITPR2

5.76e-042256231286141
Pubmed

Replication of a genome-wide case-control study of esophageal squamous cell carcinoma.

XDH PGLYRP2

8.71e-042756218649358
Pubmed

Expression of Robo/Slit and Semaphorin/Plexin/Neuropilin family members in the developing hypothalamic paraventricular and supraoptic nuclei.

SRGAP3 PLXNA4

9.37e-042856218617019
Pubmed

Overlapping Activities of Two Neuronal Splicing Factors Switch the GABA Effect from Excitatory to Inhibitory by Regulating REST.

CACNA1D PTPRK BBS9

1.17e-0312856330995482
Pubmed

Anchoring of the 26S proteasome to the organellar membrane by FKBP38.

PTPRK PSMA1

1.22e-033256217573772
Pubmed

ESYT1 tethers the ER to mitochondria and is required for mitochondrial lipid and calcium homeostasis.

TAOK2 HDAC6 RTN3 ITPR2

1.38e-0329956437931956
Pubmed

Germline variation in apoptosis pathway genes and risk of non-Hodgkin's lymphoma.

BCL2L11 BIRC3

1.46e-033556220855536
Cytoband7q34

TRBV6-9 TRBV6-8 TRBV6-7 TRBV6-6 TRBV6-3 TRBV6-2

5.91e-081675667q34
CytobandEnsembl 112 genes in cytogenetic band chr7q34

TRBV6-8 TRBV6-7 TRBV6-6 TRBV6-2

7.96e-05185564chr7q34
GeneFamilyT cell receptor beta locus at 7q34

TRBV6-9 TRBV6-8 TRBV6-7 TRBV6-6 TRBV6-3 TRBV6-2

3.51e-0887406372
GeneFamilyMitogen-activated protein kinase kinase kinases|RAF family

TAOK2 TAOK3 TAOK1

1.97e-0524403654
GeneFamilyRho GTPase activating proteins|F-BAR domain containing

SRGAP3 SRGAP1

1.17e-03234021288
GeneFamilyRho GTPase activating proteins|BCH domain containing

SRGAP3 SRGAP1

5.47e-0350402721
GeneFamilyGATA zinc finger domain containing|Myb/SANT domain containing

MIER3 MYBL1

6.12e-0353402532
GeneFamilyArmadillo repeat containing|Protein phosphatase 1 regulatory subunits

ARFGEF3 HDAC6 SACS

7.43e-03181403694
CoexpressionAtlasDevelopingGonad_e16.5_ovary_emap-9563_top-relative-expression-ranked_1000

M1AP BCL2L11 MEIOC PTPRK SACS MIER3 TAOK1 CHD8 HERC1 MYBL1 ITPR2

2.29e-067955111gudmap_developingGonad_e16.5_ovary_1000
CoexpressionAtlasDevelopingGonad_e14.5_ ovary_emap-6699_top-relative-expression-ranked_1000

M1AP BCL2L11 MEIOC PTPRK SACS MIER3 TAOK1 CHD8 HERC1 MYBL1

1.32e-057765110gudmap_developingGonad_e14.5_ ovary_1000
CoexpressionAtlasDevelopingGonad_e18.5_ovary_emap-12283_top-relative-expression-ranked_1000

BCL2L11 MEIOC PTPRK SACS MIER3 TAOK1 CHD8 HERC1 MYBL1 ITPR2

1.35e-057785110gudmap_developingGonad_e18.5_ovary_1000
CoexpressionAtlasDevelopingGonad_e14.5_ ovary_emap-6699_top-relative-expression-ranked_500

M1AP MEIOC SACS TAOK1 CHD8 HERC1 MYBL1

3.38e-05382517gudmap_developingGonad_e14.5_ ovary_500
CoexpressionAtlasDevelopingGonad_e14.5_ epididymis_emap-29141_k-means-cluster#3_top-relative-expression-ranked_1000

BCL2L11 MIER3 TAOK1 CHD8 HERC1 MYBL1

4.93e-05275516gudmap_developingGonad_e14.5_ epididymis_1000_k3
CoexpressionAtlasDevelopingGonad_e14.5_ ovary_emap-6699_k-means-cluster#5_top-relative-expression-ranked_100

M1AP MEIOC MYBL1

7.41e-0534513gudmap_developingGonad_e14.5_ ovary_100_k5
CoexpressionAtlasDevelopingGonad_e18.5_ovary_emap-12283_k-means-cluster#2_top-relative-expression-ranked_1000

BCL2L11 PTPRK MIER3 TAOK1 CHD8

1.46e-04210515gudmap_developingGonad_e18.5_ovary_1000_k2
CoexpressionAtlasDevelopingGonad_e14.5_ ovary_emap-6699_k-means-cluster#1_top-relative-expression-ranked_1000

M1AP MEIOC SACS TAOK1 MYBL1

1.46e-04210515gudmap_developingGonad_e14.5_ ovary_1000_k1
CoexpressionAtlasDevelopingGonad_e16.5_epididymis_emap-29702_k-means-cluster#3_top-relative-expression-ranked_500

TAOK1 CHD8 HERC1

1.72e-0445513gudmap_developingGonad_e16.5_epididymis_500_k3
CoexpressionAtlasDevelopingGonad_e14.5_ ovary_emap-6699_k-means-cluster#3_top-relative-expression-ranked_500

M1AP MEIOC SACS MYBL1

1.85e-04118514gudmap_developingGonad_e14.5_ ovary_500_k3
CoexpressionAtlasDevelopingGonad_e16.5_ovary_emap-9563_k-means-cluster#2_top-relative-expression-ranked_1000

BCL2L11 PTPRK MIER3 TAOK1 CHD8

2.23e-04230515gudmap_developingGonad_e16.5_ovary_1000_k2
CoexpressionAtlasDevelopingGonad_e16.5_epididymis_emap-29702_k-means-cluster#4_top-relative-expression-ranked_1000

MIER3 CHD8 HERC1 MYBL1

2.45e-04127514gudmap_developingGonad_e16.5_epididymis_1000_k4
CoexpressionAtlasdev gonad_e13.5_F_VascAssocMesenchStromOvary_MafB_top-relative-expression-ranked_200

CACNA1D SRGAP3 PLXNA4 ITPR2

3.28e-04137514gudmap_dev gonad_e13.5_F_VascAssocMesenchStromOvary_MafB_200
CoexpressionAtlasDevelopingGonad_e12.5_epididymis_emap-29139_k-means-cluster#5_top-relative-expression-ranked_1000

TAOK1 CHD8 HERC1 MYBL1

3.37e-04138514gudmap_developingGonad_e12.5_epididymis_k5_1000
CoexpressionAtlasDevelopingGonad_e18.5_epididymis_emap-13166_top-relative-expression-ranked_500

BCL2L11 PTPRK TAOK1 CHD8 HERC1 MYBL1

3.99e-04404516gudmap_developingGonad_e18.5_epididymis_500
CoexpressionAtlasDevelopingGonad_e14.5_ ovary_emap-6699_top-relative-expression-ranked_200

M1AP MEIOC CHD8 MYBL1

4.39e-04148514gudmap_developingGonad_e14.5_ ovary_200
CoexpressionAtlasDevelopingGonad_P2_ovary_emap-30224_top-relative-expression-ranked_1000

BCL2L11 PLXNA4 XDH TAOK1 CHD8 HERC1 MYBL1 ITPR2

4.61e-04770518gudmap_developingGonad_P2_ovary_1000
CoexpressionAtlasDevelopingGonad_e16.5_epididymis_emap-29702_top-relative-expression-ranked_1000

BCL2L11 TRIO PTPRK MIER3 TAOK1 CHD8 HERC1 MYBL1

5.46e-04790518gudmap_developingGonad_e16.5_epididymis_1000
CoexpressionAtlasdev gonad_e13.5_F_SupCellPrec_Sry_k-means-cluster#3_top-relative-expression-ranked_1000

CACNA1D SACS SRGAP3 ZNF280C ITPR2

5.59e-04281515gudmap_dev gonad_e13.5_F_SupCellPrec_Sry_k3_1000
CoexpressionAtlasDevelopingGonad_e18.5_epididymis_emap-13166_k-means-cluster#3_top-relative-expression-ranked_500

CHD8 HERC1 MYBL1

5.61e-0467513gudmap_developingGonad_e18.5_epididymis_500_k3
CoexpressionAtlasDevelopingGonad_P2_epididymis_emap-30199_top-relative-expression-ranked_1000

BMPR1B BCL2L11 PTPRK MIER3 TAOK1 CHD8 HERC1 MYBL1

5.79e-04797518gudmap_developingGonad_P2_epididymis_1000
CoexpressionAtlasdev gonad_e12.5_F_GermCellOvary_Oct_k-means-cluster#2_top-relative-expression-ranked_500

M1AP MEIOC MYBL1

5.86e-0468513gudmap_dev gonad_e12.5_F_GermCellOvary_Oct_k2_500
CoexpressionAtlasDevelopingGonad_e18.5_epididymis_emap-13166_top-relative-expression-ranked_1000

BCL2L11 TRIO PTPRK MIER3 TAOK1 CHD8 HERC1 MYBL1

5.89e-04799518gudmap_developingGonad_e18.5_epididymis_1000
CoexpressionAtlasDevelopingGonad_e14.5_ epididymis_emap-29141_top-relative-expression-ranked_1000

BCL2L11 TRIO PTPRK MIER3 TAOK1 CHD8 HERC1 MYBL1

5.99e-04801518gudmap_developingGonad_e14.5_ epididymis_1000
CoexpressionAtlasDevelopingGonad_e14.5_ ovary_emap-6699_top-relative-expression-ranked_100

M1AP MEIOC MYBL1

6.38e-0470513gudmap_developingGonad_e14.5_ ovary_100
CoexpressionAtlasdev gonad_e13.5_F_VascAssocMesenchStromOvary_MafB_k-means-cluster#1_top-relative-expression-ranked_1000

CACNA1D SRGAP3 ZNF280C ITPR2

6.76e-04166514gudmap_dev gonad_e13.5_F_VascAssocMesenchStromOvary_MafB_k1_1000
CoexpressionAtlasdev gonad_e13.5_F_SupCellPrec_Sry_top-relative-expression-ranked_100

CACNA1D PLXNA4 ITPR2

8.75e-0478513gudmap_dev gonad_e13.5_F_SupCellPrec_Sry_100
ToppCellTracheal-NucSeq-Epithelial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

ARFGEF3 TBC1D30 PTPRK SRGAP3 SRGAP1 MYO5C

1.73e-07200556d3af0a706baf66e3f32e67b17dcfc31e5b32ce0e
ToppCellCOVID-19-Epithelial_cells-Airway_basal|COVID-19 / group, cell type (main and fine annotations)

UGT1A3 ARFGEF3 BMPR1B PTPRK SRGAP3

3.46e-061875558407a82e98f56a94ea26562bcb6bbe00a8f41661
ToppCell10x_5'_v1-Non-neoplastic-Lymphoid-CD4/CD8-Reg_T-F_2|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

BCL2L11 ZNF280C TRBV6-6 BIRC3 MYO5C

4.45e-0619755554fb7197db3c0dc87a1114e1ab1d2bfafd564b35
ToppCellBronchial-NucSeq-Epithelial-Epi_submucosal-gland-SMG_Mucous|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

ARFGEF3 BMPR1B TBC1D30 SRGAP3 SRGAP1

4.79e-06200555ed093626a9cac7531a2bf02f6e345c5e84b8c060
ToppCellBronchial-NucSeq-Epithelial-Epi_submucosal-gland|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

ARFGEF3 TBC1D30 SRGAP3 SRGAP1 XDH

4.79e-0620055585c0f038bcfb42669dca2b80273b0f8a1421405e
ToppCell3'_v3-Lung-Lymphocytic_T_CD4/8-lo-Trm_Tgd|Lung / Manually curated celltypes from each tissue

SRGAP3 TRBV6-3 PLXNA4 PRPF39

2.86e-05142554c3db15bcb305ebdf5c9ca0b5c8ce63fab978590b
ToppCelldroplet-Spleen-nan-18m-Myeloid-granulocyte|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SRGAP1 MROH2A XDH DENND5A

4.90e-05163554bc37c5d9f48b16096d5313657563f3ec84028c8c
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d03-09-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c03-ITGA4|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)

SACS TRBV6-2 BIRC3 MYBL1

5.39e-0516755483969c36ac44b96afc9aa09400a99fa2b487f7ff
ToppCellBAL-Mild-cDC_3|Mild / Compartment, Disease Groups and Clusters

DOCK5 SRGAP3 SRGAP1 ITPR2

6.60e-05176554f9b0c3ced391e7ebe6b242d3f12ba14741f88d22
ToppCellRV-11._Adipocyte|World / Chamber and Cluster_Paper

PSMA1 PLXNA4 RTN3 ITPR2

6.75e-05177554f0edf04930692418953e4f00a917257804ec0ffd
ToppCellRV-11._Adipocyte|RV / Chamber and Cluster_Paper

PSMA1 PLXNA4 RTN3 ITPR2

6.90e-05178554278bbea5cf8f0589f71675c7a3d00679391b5253
ToppCell3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.0.5|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SRGAP3 SGSM2 SRGAP1 MYO5C

7.05e-051795546e965e424eebef50f0202cff75f458be395cfca1
ToppCellBAL-Control-Lymphocyte-T/NK-CD4+_T-CD4+_T_activated|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

TRBV6-6 BIRC3 PGLYRP2 MYBL1

7.05e-0517955435f014b6e752626909d829c5ab9bb761c1f3e3dc
ToppCellBAL-Control-Lymphocyte-T/NK-CD4+_T-CD4+_T_activated-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

TRBV6-6 BIRC3 PGLYRP2 MYBL1

7.05e-05179554a634ca46ffc394c5f5215fc5d8eae4a77819af9c
ToppCellChildren_(3_yrs)-Epithelial-club_cell-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

ARFGEF3 BMPR1B PLXNA4 XDH

7.21e-05180554b509c7d6bdfba672065fb722874bdc68de72ba1c
ToppCellChildren_(3_yrs)-Epithelial-club_cell-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

ARFGEF3 BMPR1B SRGAP3 XDH

7.52e-05182554215c303df42f13597b2c7a95cb157c6bc7aca9a1
ToppCellCalu_3-infected|Calu_3 / Cell line, Condition and Strain

TRIO BIRC3 TAOK1 CHD8

7.68e-051835548f7f5000645f24f20a8d7700c4df1f8953a1780b
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_C_(IT_L4_RORB)|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

BMPR1B PTPRK PLXNA4 ITPR2

7.85e-051845546475a43201b136dcc9b113d2ca4cfa154ed9d65d
ToppCellCOVID-19-Epithelial_cells-Airway_club|COVID-19 / group, cell type (main and fine annotations)

ARFGEF3 BMPR1B PTPRK MYO5C

8.01e-05185554cfe6fd73d817e173fe803bc1683c291d9bcb8608
ToppCellpdx-Tumor_cells-T0|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)

CACNA1D TAOK3 PTPRK ITPR2

8.01e-051855541d874608aa2062024323512f68889219471b2f00
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

ARFGEF3 BMPR1B PTPRK MYO5C

8.18e-051865542ea5ff14861e5f91d0e6a5767c403a24045d715c
ToppCellAdult-Epithelial-club_cell-D231|Adult / Lineage, Cell type, age group and donor

ARFGEF3 BMPR1B SRGAP3 PLXNA4

8.35e-05187554ee59d7d3de5879738ff0b9c3ea5e4847fb48cb86
ToppCellRA-11._Adipocyte|World / Chamber and Cluster_Paper

PSMA1 PLXNA4 RTN3 ITPR2

8.52e-051885544dac9d636e5cad4cda540b93d4bfed6b5732c880
ToppCellControl-Epithelial_cells|Control / group, cell type (main and fine annotations)

DOCK5 ARFGEF3 PTPRK MYO5C

8.52e-05188554707ebf76cc6fb600b2f07793cf4ea9482c0de79d
ToppCellCOVID-19-lung-Secretory|lung / Disease (COVID-19 only), tissue and cell type

ARFGEF3 BMPR1B SRGAP3 MYO5C

8.70e-0518955484d48e3ed25bebb8bb8074b3a2c5e2e88cff7f25
ToppCellAdult-Epithelial-club_cell|Adult / Lineage, Cell type, age group and donor

ARFGEF3 BMPR1B SRGAP3 PLXNA4

8.88e-05190554756bff697d30aec56c0ebfca94295f084a15bf37
ToppCellCOVID-19-Epithelial_cells-Airway_goblet|COVID-19 / group, cell type (main and fine annotations)

ARFGEF3 BMPR1B SRGAP3 MYO5C

8.88e-0519055451ca9ef4df3220487152fcf684147730637c7cc1
ToppCellCOVID-19-lung-Secretory|COVID-19 / Disease (COVID-19 only), tissue and cell type

ARFGEF3 BMPR1B SRGAP3 MYO5C

9.25e-0519255459261098ccb52306f837f632ebaea45b90ad30fe
ToppCellPCW_05-06-Mesenchymal-Mesenchymal_fibroblastic-mes_chondroblast_(18)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

BMPR1B SRGAP3 SRGAP1 ITPR2

9.25e-05192554d0649410cf5eacdb0c1dce70e37c7473ef5fddfa
ToppCellTCGA-Prostate-Primary_Tumor-Prostate_Adenocarcinoma-Acinar_Adenocarcinoma-6|TCGA-Prostate / Sample_Type by Project: Shred V9

ARFGEF3 FOXN2 PTPRK TAOK1

9.43e-05193554abd71b2cf667ef2b1c4d88acd0c1dd19a12ff659
ToppCellEpithelial-club_cell|World / Lineage, Cell type, age group and donor

ARFGEF3 BMPR1B PTPRK XDH

9.43e-051935542bdd09004fa433550958ec42ba4b06271a4aaf7c
ToppCellNS-moderate-d_16-33-Epithelial-Secretory|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

ARFGEF3 PTPRK SRGAP1 MYO5C

1.00e-0419655470384c1da9baed843f414cfd1403ddd586a2db07
ToppCellIPF-Epithelial|IPF / Disease state, Lineage and Cell class

ARFGEF3 BMPR1B PTPRK SRGAP3

1.00e-0419655487d9881cfec461a5d89b688a83749b618c519485
ToppCellBronchial-10x5prime-Immune_Lymphocytic-T-T_CD4-CD4|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

TRBV6-6 BIRC3 PGLYRP2 MYBL1

1.02e-041975544bc76958ca12af2dd490d4865de6a92554a14656
ToppCellFetal_29-31_weeks-Epithelial-club_cell-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

ARFGEF3 BMPR1B TBC1D30 XDH

1.04e-041985546ba5e5970109a04ed968bac7ff099ae250c579dc
ToppCellFetal_29-31_weeks-Epithelial-club_cell|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

ARFGEF3 BMPR1B TBC1D30 XDH

1.04e-041985545fc25b008a4d8d6bec83923a16f64dd9e1ff1f2d
ToppCellParenchymal-NucSeq-Epithelial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

DOCK5 ARFGEF3 PTPRK MYO5C

1.06e-041995545cea0d9e261903e0eaad60c28a07dff72ce65027
ToppCellTracheal-NucSeq-Epithelial-Epi_submucosal-gland|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

ARFGEF3 TBC1D30 SRGAP1 MYO5C

1.08e-042005540eb9ad8c0373bcc62029ec21c590ed03aaacd039
ToppCellNeuron-Postmitotic-Excitatory_Neuron_-Upper_Layer_Occipital|World / Primary Cells by Cluster

ARFGEF3 PTPRK SRGAP1 PLXNA4

1.08e-042005546bbe8e1f3e91678f1bfb14945365c1578a59a604
ToppCellNeuron-Postmitotic-Excitatory_Neuron_-Upper_Layer_Occipital-19|World / Primary Cells by Cluster

ARFGEF3 PTPRK SRGAP1 PLXNA4

1.08e-04200554c831d9e0a7178e3634da45548f91fa9e8dc6557c
DrugRapamycin; Down 200; 0.1uM; HL60; HT_HG-U133A

TAOK2 TBC1D30 SGSM2 MFN2 MLLT10 MYBL1

3.65e-061944966201_DN
Diseasecentral nervous system disease (implicated_via_orthology)

TAOK2 TAOK3 TAOK1

2.37e-0616493DOID:331 (implicated_via_orthology)
Diseaseautism spectrum disorder (implicated_via_orthology)

TAOK2 TAOK3 TAOK1 CHD8

1.20e-04152494DOID:0060041 (implicated_via_orthology)
Diseasefree cholesterol:total lipids ratio, high density lipoprotein cholesterol measurement

PRKAG3 INTS10 BCL2L11 MYO1H NTN5

1.46e-04303495EFO_0004612, EFO_0020945
Diseaseinsomnia, bilirubin measurement

UGT1A3 MROH2A

1.47e-0411492EFO_0004570, EFO_0004698
Diseasechylomicron measurement, very low density lipoprotein cholesterol measurement

PRKAG3 INTS10 MYO1H

7.36e-04106493EFO_0008317, EFO_0008596
DiseaseInvolutional paraphrenia

GAD2 XDH

7.91e-0425492C1571983
DiseasePsychosis, Involutional

GAD2 XDH

7.91e-0425492C1571984
DiseaseInvolutional Depression

GAD2 XDH

7.91e-0425492C0011574
Diseasefree cholesterol measurement, chylomicron measurement, very low density lipoprotein cholesterol measurement

PRKAG3 INTS10 MYO1H

8.20e-04110493EFO_0008317, EFO_0008591, EFO_0008596
DiseaseIntellectual Disability

TRIO SACS SRGAP3 TAOK1 CHD8

8.60e-04447495C3714756
Diseasecholesterol:total lipids ratio, high density lipoprotein cholesterol measurement

PRKAG3 INTS10 BCL2L11 MYO1H

1.14e-03276494EFO_0004612, EFO_0020943
Diseasemalignant epithelial tumor of ovary

SRGAP1 MLLT10

1.55e-0335492MONDO_0018364

Protein segments in the cluster

PeptideGeneStartEntry
MLNNMSLVYHRSCVE

UGT1A3

116

P35503
QSMTLQCAQDMNHNY

TRBV6-6

36

A0A0A6YYG2
VDAMFSLNCSQYHSM

URB2

616

Q14146
SFLAARMNYMQNHQA

CHD8

1956

Q9HCK8
RFMQEHTCYDAMATS

PRKAG3

186

Q9UGI9
CQAFNHYLSAMASMR

BCL2L11

121

O43521
ALMRSSYHCAMNNEN

BIRC3

156

Q13489
SLNRNHFQSYIMADM

BMPR1B

386

O00238
AETMRHIFMNNYHLC

ITPR2

1271

Q14571
HRMKDLCRYMNNFDS

INTS10

286

Q9NVR2
EEGLMQNCNQMHASY

GAD2

411

Q05329
MSLFSLYMVQDQHEC

M1AP

61

Q8TC57
TNNMNMSRASVYAAH

LIPM

281

Q5VYY2
NCRSIDMDNYMLSRN

HERC1

4836

Q15751
NSSNYAFMQALMHAV

GDF3

306

Q9NR23
DQDMNAYLAEQSRMH

PLXNA4

1826

Q9HCM2
AYLAEQSRMHMNEFN

PLXNA4

1831

Q9HCM2
LSHSYCLHQNMMRLA

OR51H1

176

Q8NH63
AANMRSMQRYHQDTQ

PGLYRP2

426

Q96PD5
YLERHMSEFMECNLN

PSMA1

171

P25786
YHSELNPMNMCSEES

MIER3

461

Q7Z3K6
MQNSHMDEYRNSSNG

PRPF39

1

Q86UA1
MYEHNLQRTACNMTY

BBS9

126

Q3SYG4
MDSLHMAAREQQVYC

MFN2

376

O95140
CMIALLQQMDDSHYS

DOCK5

956

Q9H7D0
QMLMNADSLYTAAHC

ARFGEF3

726

Q5TH69
ICSAMQTLYHMHNAE

DENND5A

146

Q6IQ26
MSDQMQRHSYCNLKD

MARVELD1

116

Q9BSK0
DHNYSASSMAAQRCA

FOXN2

301

P32314
TGLVYDQNMMNHCNL

HDAC6

481

Q9UBN7
ALLMYFNCNLNHLMS

SACS

3386

Q9NZJ4
MLNTLCLAMQHYEQS

CACNA1D

1216

Q01668
PCAAMDHMQTQNQFY

MYBL1

211

P10243
HMVNAMDRSYADQST

PTPRK

796

Q15262
QHQYSSQNLMEMVHC

MROH2A

361

A6NES4
TLSSEAFHNYMNAAM

RTN3

921

O95197
AFHNYMNAAMVHINR

RTN3

926

O95197
QVSCFSNNYMMGDLR

MEIOC

661

A2RUB1
SNNYMMGDLRHNQCF

MEIOC

666

A2RUB1
AFLNHLSQYSDENMM

SRGAP1

636

Q7Z6B7
QNYCNMSDTRVHMSL

NTN5

346

Q8WTR8
AYSCFSHLMKRMSQN

SGSM2

856

O43147
FNMNAMSALYHIAQN

TAOK1

226

Q7L7X3
FNMNAMSALYHIAQN

TAOK2

226

Q9UL54
LFNMNAMSALYHIAQ

TAOK3

221

Q9H2K8
HMYGNRSNSSMAALI

MLLT10

641

P55197
QSMTLLCAQDMNHEY

TRBV6-2

36

A0A0J9YXY3
AFLNHLSQYSDENMM

SRGAP3

636

O43295
SMRCFQQAHYDMRRN

RAPGEF1

1021

Q13905
QSMTLLCAQDMNHEY

TRBV6-3

36

P0DPF7
QSIMERALFHMDNCY

XDH

876

P47989
SCRSEYHAAFNSMMM

TBC1D30

616

Q9Y2I9
QSMTLLCAQDMNHEY

TRBV6-7

36

A0A0A0MS04
QSMTLQCAQDMNHGY

TRBV6-8

36

A0A0A6YYG3
YNTNCNKAFVNHMMS

ZNF280C

646

Q8ND82
QSMTLQCAQDMNHGY

TRBV6-9

36

A0A0J9YX75
QTQHNHFAMNCMNVY

TRIO

381

O75962
HFAMNCMNVYVNINR

TRIO

386

O75962
DNAYRMMCAELNNHF

MYO1H

86

Q8N1T3
FMCVRYADSLNDANM

MYO5C

1401

Q9NQX4