Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionglutathione binding

GSTM1 GSTM2 GSTM4 GSTM5

1.03e-05181574GO:0043295
GeneOntologyMolecularFunctionoligopeptide binding

GSTM1 GSTM2 GSTM4 GSTM5

1.62e-05201574GO:1900750
GeneOntologyMolecularFunctionABC-type transporter activity

ATP13A1 ABCC5 ABCC11 ABCC6 ABCC12

4.07e-05491575GO:0140359
GeneOntologyMolecularFunctionmodified amino acid binding

SYT3 SYT6 GSTM1 GSTM2 GSTM4 GSTM5 GSDMA

5.11e-051221577GO:0072341
GeneOntologyMolecularFunctionATPase-coupled inorganic anion transmembrane transporter activity

ABCC5 ABCC11 ABCC6

5.50e-05101573GO:0043225
GeneOntologyMolecularFunctionglutathione transferase activity

GSTM1 GSTM2 GSTM4 GSTM5

7.49e-05291574GO:0004364
GeneOntologyMolecularFunctionATP hydrolysis activity

RAD51 VWA8 ATP13A1 ABCC5 ABCC11 MCM6 SMC2 ABCC6 NAV1 DDX23 MACF1 ABCC12

1.97e-0444115712GO:0016887
GeneOntologyMolecularFunctionABC-type xenobiotic transporter activity

ABCC5 ABCC11 ABCC6

2.02e-04151573GO:0008559
GeneOntologyBiologicalProcessnitrobenzene metabolic process

GSTM1 GSTM2 GSTM4

1.69e-0641563GO:0018916
GeneOntologyBiologicalProcessactomyosin contractile ring assembly

ANLN PLEC IQGAP3

3.45e-0591563GO:0000915
GeneOntologyBiologicalProcessassembly of actomyosin apparatus involved in cytokinesis

ANLN PLEC IQGAP3

3.45e-0591563GO:0000912
GeneOntologyBiologicalProcessactomyosin contractile ring organization

ANLN PLEC IQGAP3

4.90e-05101563GO:0044837
DomainGST_mu

GSTM1 GSTM2 GSTM4 GSTM5

2.39e-0851574IPR003081
DomainGST_N

GSTM1 GSTM2 GSTM4 GSTM5

3.12e-05221574PF02798
DomainGST_NTER

GSTM1 GSTM2 GSTM4 GSTM5

3.12e-05221574PS50404
DomainABC_membrane

ABCC5 ABCC11 ABCC6 ABCC12

4.48e-05241574PF00664
DomainGST_C

GSTM1 GSTM2 GSTM4 GSTM5

6.22e-05261574IPR004046
DomainGST_C

GSTM1 GSTM2 GSTM4 GSTM5

6.22e-05261574PF00043
DomainGlutathione_S-Trfase_N

GSTM1 GSTM2 GSTM4 GSTM5

7.25e-05271574IPR004045
DomainABC_TM1F

ABCC5 ABCC11 ABCC6 ABCC12

8.41e-05281574PS50929
DomainABC1_TM_dom

ABCC5 ABCC11 ABCC6 ABCC12

8.41e-05281574IPR011527
DomainSpectrin_repeat

MCF2 SYNE2 MACF1 PLEC

9.69e-05291574IPR002017
DomainSPEC

MCF2 SYNE2 MACF1 PLEC

1.44e-04321574SM00150
DomainSpectrin/alpha-actinin

MCF2 SYNE2 MACF1 PLEC

1.44e-04321574IPR018159
DomainGST_CTER

GSTM1 GSTM2 GSTM4 GSTM5

1.83e-04341574PS50405
DomainCadherin_2

PCDHGA10 PCDHGA5 PCDHGA3 PCDHGA1 PCDH8

2.17e-04651575PF08266
DomainCadherin_N

PCDHGA10 PCDHGA5 PCDHGA3 PCDHGA1 PCDH8

2.17e-04651575IPR013164
DomainAAA

RAD51 VWA8 ABCC5 ABCC11 ABCC6 NAV1 ABCC12

2.18e-041441577SM00382
DomainAAA+_ATPase

RAD51 VWA8 ABCC5 ABCC11 ABCC6 NAV1 ABCC12

2.18e-041441577IPR003593
DomainCadherin_tail

PCDHGA10 PCDHGA5 PCDHGA3 PCDHGA1

2.56e-04371574PF15974
DomainCadherin_CBD

PCDHGA10 PCDHGA5 PCDHGA3 PCDHGA1

2.56e-04371574IPR031904
DomainGlutathione-S-Trfase_C-like

GSTM1 GSTM2 GSTM4 GSTM5

3.14e-04391574IPR010987
Domain-

GSTM1 GSTM2 GSTM4 GSTM5

3.14e-043915741.20.1050.10
DomainCadherin_CS

PCDHGA10 PCDHGA5 PCDHGA3 CDHR1 PCDHGA1 PCDH8

3.18e-041091576IPR020894
DomainCADHERIN_1

PCDHGA10 PCDHGA5 PCDHGA3 CDHR1 PCDHGA1 PCDH8

3.86e-041131576PS00232
DomainCadherin

PCDHGA10 PCDHGA5 PCDHGA3 CDHR1 PCDHGA1 PCDH8

3.86e-041131576PF00028
DomainCADHERIN_2

PCDHGA10 PCDHGA5 PCDHGA3 CDHR1 PCDHGA1 PCDH8

4.05e-041141576PS50268
Domain-

PCDHGA10 PCDHGA5 PCDHGA3 CDHR1 PCDHGA1 PCDH8

4.05e-0411415762.60.40.60
DomainDC_STAMP-like

DCST2 DCSTAMP

4.17e-0441572IPR012858
DomainDC_STAMP

DCST2 DCSTAMP

4.17e-0441572PF07782
DomainABC_transporter_CS

ABCC5 ABCC11 ABCC6 ABCC12

4.19e-04421574IPR017871
DomainCadherin_C

PCDHGA10 PCDHGA5 PCDHGA3 PCDHGA1

4.19e-04421574IPR032455
DomainCadherin_C_2

PCDHGA10 PCDHGA5 PCDHGA3 PCDHGA1

4.19e-04421574PF16492
DomainCA

PCDHGA10 PCDHGA5 PCDHGA3 CDHR1 PCDHGA1 PCDH8

4.24e-041151576SM00112
DomainCadherin-like

PCDHGA10 PCDHGA5 PCDHGA3 CDHR1 PCDHGA1 PCDH8

4.45e-041161576IPR015919
DomainCadherin

PCDHGA10 PCDHGA5 PCDHGA3 CDHR1 PCDHGA1 PCDH8

4.87e-041181576IPR002126
DomainABC_tran

ABCC5 ABCC11 ABCC6 ABCC12

7.01e-04481574PF00005
DomainABC_TRANSPORTER_2

ABCC5 ABCC11 ABCC6 ABCC12

7.01e-04481574PS50893
DomainABC_TRANSPORTER_1

ABCC5 ABCC11 ABCC6 ABCC12

7.59e-04491574PS00211
DomainABC_transporter-like

ABCC5 ABCC11 ABCC6 ABCC12

8.19e-04501574IPR003439
DomainACTININ_2

SYNE2 MACF1 PLEC

9.12e-04231573PS00020
DomainACTININ_1

SYNE2 MACF1 PLEC

9.12e-04231573PS00019
DomainActinin_actin-bd_CS

SYNE2 MACF1 PLEC

9.12e-04231573IPR001589
Domain-

MACF1 PLEC

1.03e-03615723.90.1290.10
DomainPlectin

MACF1 PLEC

1.43e-0371572PF00681
DomainPlectin_repeat

MACF1 PLEC

1.43e-0371572IPR001101
DomainPAP_assoc

MTPAP TENT2

1.43e-0371572PF03828
DomainPAP_assoc

MTPAP TENT2

1.43e-0371572IPR002058
DomainPLEC

MACF1 PLEC

1.43e-0371572SM00250
DomainCH

SYNE2 MACF1 PLEC IQGAP3

2.18e-03651574SM00033
PathwayKEGG_MEDICUS_ENV_FACTOR_DCE_TO_DNA_ADDUCTS

GSTM1 GSTM2 GSTM4 GSTM5

6.94e-0619954M47809
PathwayKEGG_MEDICUS_ENV_FACTOR_TCDD_TO_AHR_SIGNALING_PATHWAY

GSTM1 GSTM2 GSTM4 GSTM5

1.55e-0523954M47806
PathwayKEGG_MEDICUS_REFERENCE_KEAP1_NRF2_SIGNALING_PATHWAY

GSTM1 GSTM2 GSTM4 GSTM5

1.85e-0524954M47487
PathwayWP_OXIDATIVE_STRESS_AND_REDOX_PATHWAY

ABCC5 GSTM1 GSTM2 GSTM4 GSTM5 TXNRD3

3.57e-0592956MM15823
PathwayWP_NRF2_PATHWAY

ABCC5 SLC39A4 GSTM1 GSTM2 GSTM4 GSTM5 TXNRD3

4.58e-05141957M39454
PathwayREACTOME_GLUTATHIONE_CONJUGATION

GSTM1 GSTM2 GSTM4 GSTM5

9.66e-0536954M1443
PathwayREACTOME_GLUTATHIONE_CONJUGATION

GSTM1 GSTM2 GSTM4 GSTM5

1.20e-0438954MM14600
PathwayKEGG_ABC_TRANSPORTERS

ABCC5 ABCC11 ABCC6 ABCC12

2.14e-0444954M11911
PathwayREACTOME_OTHER_SEMAPHORIN_INTERACTIONS

ITGA1 PLXNA4 SEMA3E

2.66e-0419953M10959
PathwayKEGG_GLUTATHIONE_METABOLISM

GSTM1 GSTM2 GSTM4 GSTM5

3.52e-0450954M1840
Pubmed

Glutathione S-transferase variants and hypertension.

GSTM1 GSTM2 GSTM4 GSTM5

2.20e-095161418551009
Pubmed

Genetic variants in GSTM3 gene within GSTM4-GSTM2-GSTM1-GSTM5-GSTM3 cluster influence breast cancer susceptibility depending on GSTM1.

GSTM1 GSTM2 GSTM4 GSTM5

2.20e-095161419856098
Pubmed

Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.

HK1 POLR1A RARS1 SHMT2 MCM6 PSMD5 CMSS1 SMC2 EPB41L3 MTPAP RLF TGM2 URB1 ARHGEF40 ANLN WDR6 TUBGCP3 ASS1 PDCD11 DDX23 GSDMA MACF1 SCRIB PLEC

1.75e-0813531612429467282
Pubmed

Small Extracellular Vesicles Have GST Activity and Ameliorate Senescence-Related Tissue Damage.

GSTM1 GSTM2 GSTM5

9.74e-083161332574561
Pubmed

Characterization of the human class Mu glutathione S-transferase gene cluster and the GSTM1 deletion.

GSTM1 GSTM2 GSTM5

9.74e-08316139452477
Pubmed

Alternative mutations of a positively selected residue elicit gain or loss of functionalities in enzyme evolution.

GSTM1 GSTM2 GSTM4

9.74e-083161316549767
Pubmed

Deduced amino acid sequence, gene structure and chromosomal location of a novel human class Mu glutathione S-transferase, GSTM4.

GSTM1 GSTM4 GSTM5

9.74e-08316138471052
Pubmed

Identification of class-mu glutathione transferase genes GSTM1-GSTM5 on human chromosome 1p13.

GSTM1 GSTM2 GSTM5

3.88e-07416138317488
Pubmed

The inhibitory glutathione transferase M2-2 binding site is located in divergent region 3 of the cardiac ryanodine receptor.

GSTM1 GSTM2 GSTM5

3.88e-074161322406107
Pubmed

Molecular cloning and heterologous expression of an alternatively spliced human Mu class glutathione S-transferase transcript.

GSTM1 GSTM2 GSTM4

3.88e-07416138373352
Pubmed

Variation in the GST mu locus and tobacco smoke exposure as determinants of childhood lung function.

GSTM2 GSTM4 GSTM5

3.88e-074161319151192
Pubmed

Impaired plasma membrane localization of ubiquitin ligase complex underlies 3-M syndrome development.

APOBEC3D POLR1A PCDHGA3 LAMA5 APOB CMSS1 EPB41L3 MTPAP NELL1 LRRC1 NEMF MACF1 PLEC

6.07e-074961611331343991
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

RAD51 KMT2B VWA8 ATP13A1 TMEM8B LAMA5 PAPLN URB1 ARHGEF40 IER5L FAM83F PKD1 TXNRD3 NAV1 PDCD11 HMGXB3 PLEC HECTD1 IQGAP3

9.73e-0711051611935748872
Pubmed

Large-scale proteomics and phosphoproteomics of urinary exosomes.

RARS1 VPS13C SERPINF1 OLFM4 LAMA5 SHMT2 ABCC11 ITGA1 SMC2 B4GALT1 GSTM2 TGM2 PTPRJ FAM151A ASS1 PKD1 UMOD FGG

1.26e-0610161611819056867
Pubmed

Genetic interaction studies link autosomal dominant and recessive polycystic kidney disease in a common pathway.

MEOX2 PKD1 UMOD

1.93e-066161317575307
Pubmed

Purification and characterization of eight glutathione S-transferase isoenzymes of hamster. Comparison of subunit composition of enzymes from liver, kidney, testis, pancreas and trachea.

GSTM1 GSTM2 GSTM4

1.93e-06616131530570
Pubmed

Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.

DMXL2 LUC7L3 PAPLN PATL1 SMC2 MAP3K6 TGM2 ARHGEF40 WDR6 TUBGCP3 NEMF SCRIB IQGAP3 SEMA3E

2.24e-066501611438777146
Pubmed

Fibril treatment changes protein interactions of tau and α-synuclein in human neurons.

DMXL2 PSMD5 INPP5F SMC2 EPB41L3 TRIM3 DARS2 GSTM2 SYNE2 NAV1 MACF1 SCRIB

3.95e-064981611236634849
Pubmed

Pkd1 and Pkd2 are required for normal placental development.

MEOX2 PKD1 UMOD

5.36e-068161320862291
Pubmed

Tissue distribution and hepatic and renal ontogeny of the multidrug resistance-associated protein (Mrp) family in mice.

ABCC5 ABCC6 ABCC12

5.36e-068161315802388
Pubmed

HDLBP Promotes Hepatocellular Carcinoma Proliferation and Sorafenib Resistance by Suppressing Trim71-dependent RAF1 Degradation.

RARS1 LUC7L3 VWA8 ATP13A1 SHMT2 B3GALT6 APOB PATL1 CMSS1 MTPAP TRIM3 TGM2 ARHGEF40 WDR6 TUBGCP3 NEMF PDCD11 DDX23 MCAT PLEC

5.95e-0613711612036244648
Pubmed

Prediction of the coding sequences of unidentified human genes. XIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.

FRMPD1 INPP5F EPB41L3 SYNE2 EFR3B POFUT2

8.36e-06102161610231032
Pubmed

Glutathione pathway genetic polymorphisms and lung cancer survival after platinum-based chemotherapy.

GSTM1 GSTM2 GSTM4 GSTM5

1.10e-0530161420200426
Pubmed

A multi-factor trafficking site on the spliceosome remodeling enzyme BRR2 recruits C9ORF78 to regulate alternative splicing.

HK1 VWA8 SHMT2 MCM6 SMC2 COG8 NUP54 WDR6 TUBGCP3 LRRC1 DDX23 BZW1

1.28e-055601611235241646
Pubmed

Comparative DNA sequence analysis of mouse and human protocadherin gene clusters.

PCDHGA10 PCDHGA5 PCDHGA3 PCDHGA1 PCDH8

1.65e-0568161511230163
Pubmed

Direct interaction between hnRNP-M and CDC5L/PLRG1 proteins affects alternative splice site choice.

LUC7L3 SMC2 EPB41L3 ANLN TUBGCP3 LRRC1 MED12L DDX23 MACF1 BZW1 SCRIB PLEC

1.87e-055821611220467437
Pubmed

Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.

DMXL2 HK1 VWA8 ATP13A1 C1orf43 SHMT2 EPB41L3 DARS2 URB1 SNX6 WDR6 TRABD SYNE2 TUBGCP3 LRRC1 EFR3B PDCD11 DDX23 MACF1 SCRIB

1.93e-0514871612033957083
Pubmed

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.

POLR1A LUC7L3 TMEM8B VPS13C ENC1 FRMPD1 PATL1 SFMBT2 B4GALT1 RLF PTPRJ LRRC1 NEMF ASS1 NAV1 CDYL2 MACF1 CATSPERG HECTD1 CFAP69

1.97e-0514891612028611215
Pubmed

Isolation, characterization, and expression in Escherichia coli of two murine Mu class glutathione S-transferase cDNAs homologous to the rat subunits 3 (Yb1) and 4 (Yb2).

GSTM1 GSTM5

2.13e-05216122689439
Pubmed

Serum levels of pigment epithelium-derived factor, a novel marker of insulin resistance, are independently associated with fasting apolipoprotein B48 levels in humans.

SERPINF1 APOB

2.13e-052161222827961
Pubmed

LRRC1 knockdown downregulates MACF1 to inhibit the malignant progression of acute myeloid leukemia by inactivating β-catenin/c-Myc signaling.

LRRC1 MACF1

2.13e-052161238165568
Pubmed

Structure of human glutathione S-transferase class Mu genes.

GSTM2 GSTM4

2.13e-05216122006920
Pubmed

Hereditary differences in the expression of the human glutathione transferase active on trans-stilbene oxide are due to a gene deletion.

GSTM1 GSTM4

2.13e-05216123174634
Pubmed

MRP5 and MRP9 play a concerted role in male reproduction and mitochondrial function.

ABCC5 ABCC12

2.13e-052161235121660
Pubmed

The Tumor Suppressor SCRIB is a Negative Modulator of the Wnt/β-Catenin Signaling Pathway.

LRRC1 SCRIB

2.13e-052161231513346
Pubmed

Functional compensation of glutathione S-transferase M1 (GSTM1) null by another GST superfamily member, GSTM2.

GSTM1 GSTM2

2.13e-052161224048194
Pubmed

Pi-class glutathione-S-transferase-positive hepatocytes in aging B6C3F1 mice undergo apoptosis induced by dietary restriction.

GSTM1 GSTM5

2.13e-05216128909248
Pubmed

DNA methylation is associated with altered gene expression in AMD.

GSTM1 GSTM5

2.13e-052161222410570
Pubmed

Identification of a variant associated with adult-type hypolactasia.

MCM6 LCT

2.13e-052161211788828
Pubmed

Identification of residues in glutathione transferase capable of driving functional diversification in evolution. A novel approach to protein redesign.

GSTM1 GSTM2

2.13e-052161212486119
Pubmed

Quantitative assessment of the effect of glutathione S-transferase genes GSTM1 and GSTT1 on hepatocellular carcinoma risk.

GSTM1 GSTM2

2.13e-052161224399650
Pubmed

How segmental duplications shape our genome: recent evolution of ABCC6 and PKD1 Mendelian disease genes.

ABCC6 PKD1

2.13e-052161218791038
Pubmed

The T/G 13915 variant upstream of the lactase gene (LCT) is the founder allele of lactase persistence in an urban Saudi population.

MCM6 LCT

2.13e-052161217911653
Pubmed

The redox state of cytochrome c modulates resistance to methotrexate in human MCF7 breast cancer cells.

GSTM1 GSTM2

2.13e-052161223675469
Pubmed

Fibrinogen Gamma Chain Mutations Provoke Fibrinogen and Apolipoprotein B Plasma Deficiency and Liver Storage.

APOB FGG

2.13e-052161229244742
Pubmed

Genomic organization and characterization of the promoter region of murine GSTM2 gene.

GSTM1 GSTM5

2.13e-052161211404019
Pubmed

Human genes for glutathione S-transferases.

GSTM1 GSTM2

2.13e-05216126500576
Pubmed

Coagulation-driven platelet activation reduces cholestatic liver injury and fibrosis in mice.

F2RL3 FGG

2.13e-052161225353084
Pubmed

Convergent adaptation of human lactase persistence in Africa and Europe.

MCM6 LCT

2.13e-052161217159977
Pubmed

Cloning and expression of a novel Mu class murine glutathione transferase isoenzyme.

GSTM2 GSTM4

2.13e-052161212069689
Pubmed

Lymph node mapping in patients with bladder cancer undergoing radical cystectomy and lymph node dissection to the level of the inferior mesenteric artery.

SYT3 SYT6

2.13e-052161220002670
Pubmed

T Cell Recruitment to the Intestinal Stem Cell Compartment Drives Immune-Mediated Intestinal Damage after Allogeneic Transplantation.

OLFM4 ITGB7

2.13e-052161231278057
Pubmed

Multiple splicing variants of two new human ATP-binding cassette transporters, ABCC11 and ABCC12.

ABCC11 ABCC12

2.13e-052161211688999
Pubmed

A functional floxed allele of Pkd1 that can be conditionally inactivated in vivo.

MEOX2 PKD1

2.13e-052161215579506
Pubmed

Progesterone regulation of glutathione S-transferase Mu2 expression in mouse uterine luminal epithelium during preimplantation period.

GSTM1 GSTM5

2.13e-052161218692819
Pubmed

Impact of domain interchange on conformational stability and equilibrium folding of chimeric class micro glutathione transferases.

GSTM1 GSTM2

2.13e-052161212192076
Pubmed

GSTM1 and GSTM5 Genetic Polymorphisms and Expression in Age-Related Macular Degeneration.

GSTM1 GSTM5

2.13e-052161225897651
Pubmed

Two new genes from the human ATP-binding cassette transporter superfamily, ABCC11 and ABCC12, tandemly duplicated on chromosome 16q12.

ABCC11 ABCC12

2.13e-052161211483364
Pubmed

A striking organization of a large family of human neural cadherin-like cell adhesion genes.

PCDHGA10 PCDHGA5 PCDHGA3 PCDHGA1 PCDH8

2.18e-0572161510380929
Pubmed

Targeting USP10 induces degradation of oncogenic ANLN in esophageal squamous cell carcinoma.

RARS1 CMSS1 SMC2 MTPAP NUP54 GSTM1 GSTM2 TGM2 FAM83F ANLN WDR6 ASS1 NAV1 PDCD11 GSDMA SCRIB PLEC IQGAP3

2.30e-0512571611836526897
Pubmed

Cadherin superfamily genes: functions, genomic organization, and neurologic diversity.

PCDHGA10 PCDHGA5 PCDHGA3 PCDHGA1 PCDH8

2.49e-0574161510817752
Pubmed

Cell-Type-Specific Alternative Splicing Governs Cell Fate in the Developing Cerebral Cortex.

EPB41L3 SYNE2 MACF1 SCRIB

2.59e-0537161427565344
Pubmed

Phylogenetic analysis of the cadherin superfamily allows identification of six major subfamilies besides several solitary members.

PCDHGA10 PCDHGA5 PCDHGA3 PCDHGA1 PCDH8

3.02e-0577161510835267
Pubmed

Systematically defining selective autophagy receptor-specific cargo using autophagosome content profiling.

RARS1 LAMA5 APOB CMSS1 MTPAP DARS2 ARHGEF40 SNX6 ANLN WDR6 SYNE2 NEMF ASS1 PDCD11 MACF1 BZW1 HECTD1 POFUT2

3.46e-0512971611833545068
Pubmed

LMBR1L regulates lymphopoiesis through Wnt/β-catenin signaling.

POLR1A RARS1 ATP13A1 C1orf43 MCM6 CMSS1 DARS2 COG8 URB1 ARHGEF40 TRABD BZW1 SCRIB HECTD1 IQGAP3

3.49e-059421611531073040
Pubmed

Large exons encoding multiple ectodomains are a characteristic feature of protocadherin genes.

PCDHGA10 PCDHGA5 PCDHGA3 PCDHGA1 PCDH8

3.63e-0580161510716726
Pubmed

In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.

HK1 PCDHGA10 PCDHGA5 PCDHGA3 PCDHGA1 ABCC5 APOB SMC2 EPB41L3 SFMBT2 NUP54 NEK2 SYNE2 PLXNA4 DDX23 MACF1 PLEC CFAP69 POFUT2

4.17e-0514421611935575683
Pubmed

RSPO-LGR4 functions via IQGAP1 to potentiate Wnt signaling.

POLR1A VWA8 URB1 ARHGEF40 PDCD11 SCRIB IQGAP3

4.60e-05202161724639526
Pubmed

HectD1 controls hematopoietic stem cell regeneration by coordinating ribosome assembly and protein synthesis.

SMC2 EPB41L3 MTPAP HECTD1 IQGAP3

5.43e-0587161533711283
Pubmed

Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.

HK1 POLR1A MCM6 EPB41L3 URB1 WDR6 SYNE2 PDCD11 DDX23 MACF1 PLEC HECTD1

5.70e-056531611222586326
Pubmed

Altered growth characteristics of skin fibroblasts from wild-derived mice, and genetic loci regulating fibroblast clone size.

GSTM2 GSTM4

6.37e-053161216842493
Pubmed

Purification and characterization of glutathione S-transferase of murine ovary and testis.

GSTM1 GSTM5

6.37e-05316128442656
Pubmed

The structure of two murine class-mu glutathione transferase genes coordinately induced by butylated hydroxyanisole.

GSTM1 GSTM4

6.37e-05316128512323
Pubmed

Dendritic cell immunization route determines integrin expression and lymphoid and nonlymphoid tissue distribution of CD8 T cells.

ITGA1 ITGB7

6.37e-053161217237400
Pubmed

DNA repair polymorphisms and outcome of chemotherapy for acute myelogenous leukemia: a report from the Children's Oncology Group.

RAD51 GSTM1

6.37e-053161218033323
Pubmed

Homeobox genes Gsx1 and Gsx2 differentially regulate telencephalic progenitor maturation.

GSX1 GSX2

6.37e-053161221205889
Pubmed

A basis for differentiating among the multiple human Mu-glutathione S-transferases and molecular cloning of brain GSTM5.

GSTM1 GSTM5

6.37e-05316128473333
Pubmed

Genetic susceptibility, residential radon, and lung cancer in a radon prone area.

GSTM1 GSTM2

6.37e-053161224852519
Pubmed

OS9 interacts with DC-STAMP and modulates its intracellular localization in response to TLR ligation.

DCST2 DCSTAMP

6.37e-053161218952287
Pubmed

Biosynthesis of 14,15-hepoxilins in human l1236 Hodgkin lymphoma cells and eosinophils.

GSTM1 GSTM2

6.37e-053161221046276
Pubmed

A common variant in the glutathione S transferase gene is associated with elevated markers of inflammation and lipid peroxidation in subjects with diabetes mellitus.

GSTM1 GSTM2

6.37e-053161216002077
Pubmed

Gsh-1: a novel murine homeobox gene expressed in the central nervous system.

GSX1 GSX2

6.37e-05316128589431
Pubmed

Glutathione-S-transferases and Chemotherapy Resistance of Hodgkin's Lymphoma Cell Lines.

GSTM1 GSTM4

6.37e-053161227466493
Pubmed

LAP proteins are localized at the post-synaptic membrane of neuromuscular junctions and appear to modulate synaptic morphology and transmission.

LRRC1 SCRIB

6.37e-053161227321929
Pubmed

Fibrocystin/Polyductin releases a C-terminal fragment that translocates into mitochondria and suppresses cystogenesis.

MEOX2 PKD1

6.37e-053161237845212
Pubmed

An asparagine-phenylalanine substitution accounts for catalytic differences between hGSTM3-3 and other human class mu glutathione S-transferases.

GSTM4 GSTM5

6.37e-053161210587441
Pubmed

Charting the landscape of tandem BRCT domain-mediated protein interactions.

HK1 LUC7L3 DIS3L MCM6 SMC2 TULP2 SNX6 WDR6 PDCD11 DDX23 CATSPERG USH2A

7.27e-056701611222990118
Pubmed

Feto-maternal cholesterol transport regulated by β-Klotho-FGF15 axis is essential for fetal growth.

DUSP4 APOB FGFR4

8.93e-0519161337541847
Pubmed

The DNA sequence and biological annotation of human chromosome 1.

THEMIS2 TDRD5 OPN3 C1orf43 SYT6 B3GALT6 GPR52 DCST2 DARS2 RLF NEK2 TAS1R2 BRINP2 MACF1 USH2A

9.58e-0510311611516710414
Pubmed

Assembly of the U5 snRNP component PRPF8 is controlled by the HSP90/R2TP chaperones.

RARS1 LUC7L3 VWA8 SHMT2 MCM6 PATL1 CMSS1 SMC2 DARS2 SYNE2 NEMF ASS1 NAV1 DDX23 MACF1 BZW1 PLEC HECTD1

1.05e-0414151611828515276
Pubmed

Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.

HK1 POLR1A RARS1 LUC7L3 ATP13A1 VPS13C SHMT2 MCM6 APOB SMC2 EPB41L3 DARS2 URB1 WDR6 NEMF PDCD11 BZW1 IQGAP3

1.14e-0414251611830948266
Pubmed

KAP1 facilitates reinstatement of heterochromatin after DNA replication.

HK1 POLR1A SHMT2 MCM6 PSMD5 SMC2 MTPAP DARS2 ANLN PDCD11 SCRIB IQGAP3

1.16e-047041611229955894
Pubmed

Myeloid related proteins are up-regulated in autoimmune thyroid diseases and activate toll-like receptor 4 and pro-inflammatory cytokines in vitro.

ABCC11 ABCC6

1.27e-044161229656212
Pubmed

The alpha 1 beta 1 and alpha E beta 7 integrins define a subset of dendritic cells in peripheral lymph nodes with unique adhesive and antigen uptake properties.

ITGA1 ITGB7

1.27e-044161214688336
Pubmed

Molecular complex of three testis-specific isozymes associated with the mouse sperm fibrous sheath: hexokinase 1, phosphofructokinase M, and glutathione S-transferase mu class 5.

HK1 GSTM1

1.27e-044161219889946
Pubmed

Synaptotagmin-3 drives AMPA receptor endocytosis, depression of synapse strength, and forgetting.

SYT3 SYT6

1.27e-044161230545844
Pubmed

[Polymorphisms of RAD51(G135C) and XRCC3(C241T) genes and correlations thereof with prognosis and clinical outcomes of acute myeloid leukemia].

RAD51 GSTM1

1.27e-044161218581889
Pubmed

p38alpha MAP kinase as a sensor of reactive oxygen species in tumorigenesis.

GSTM1 GSTM5

1.27e-044161217292829
Pubmed

Fibrin(ogen) engagement of S. aureus promotes the host antimicrobial response and suppression of microbe dissemination following peritoneal infection.

F2RL3 FGG

1.27e-044161235041705
Pubmed

Essential role of cleavage of Polycystin-1 at G protein-coupled receptor proteolytic site for kidney tubular structure.

PKD1 UMOD

1.27e-044161218003909
InteractionGSTM2 interactions

GSTM1 GSTM2 GSTM4 GSTM5 ANLN

6.57e-07221585int:GSTM2
InteractionOBSL1 interactions

APOBEC3D POLR1A LUC7L3 LAMA5 SHMT2 MCM6 CMSS1 MTPAP NUP54 NELL1 ADPRH URB1 ATG3 SYNE2 LRRC1 NEMF PDCD11 DDX23 MACF1 SCRIB PLEC HECTD1

2.25e-0690215822int:OBSL1
InteractionGSTM5 interactions

GSTM1 GSTM2 GSTM4 GSTM5

4.64e-06151584int:GSTM5
InteractionGSTM1 interactions

GSTM1 GSTM2 GSTM5 ANLN

4.64e-06151584int:GSTM1
Cytoband1p13.3

GSTM1 GSTM2 GSTM4 GSTM5

1.05e-046916141p13.3
CytobandEnsembl 112 genes in cytogenetic band chr1p13

SYT6 SLC22A15 GSTM1 GSTM2 GSTM4 GSTM5

1.07e-042111616chr1p13
Cytoband20q13.2-q13.3

MC3R LAMA5

1.21e-045161220q13.2-q13.3
Cytoband5q35.1

GABRP RARS1 FGFR4

3.26e-043816135q35.1
Cytoband5q31

PCDHGA10 PCDHGA5 PCDHGA3 PCDHGA1

7.44e-0411516145q31
Cytoband19q13.1

KMT2B TULP2 CATSPERG

9.71e-0455161319q13.1
Cytoband2q21

MCM6 LCT

1.08e-031416122q21
GeneFamilyATP binding cassette subfamily C

ABCC5 ABCC11 ABCC6 ABCC12

9.22e-07131114807
GeneFamilyGlutathione S-transferases

GSTM1 GSTM2 GSTM4 GSTM5

1.54e-05251114567
GeneFamilyClustered protocadherins

PCDHGA10 PCDHGA5 PCDHGA3 PCDHGA1

6.44e-0464111420
GeneFamilyNon-canonical poly(A) polymerases

MTPAP TENT2

7.69e-04711121318
GeneFamilyEF-hand domain containing|Plakins

MACF1 PLEC

1.02e-0381112939
CoexpressionGSE3920_IFNA_VS_IFNB_TREATED_ENDOTHELIAL_CELL_UP

TMEM176A DARS2 TGM2 ADPRH SYNE2 LRRC1 SLC49A4 MACF1

9.83e-061691608M6700
CoexpressionGSE7218_IGM_VS_IGG_SIGNAL_THGOUGH_ANTIGEN_BCELL_UP

RAD51 DUSP4 DARS2 WDR6 PAN2 NAV1 SCRIB IQGAP3

2.05e-051871608M6807
CoexpressionGSE33292_DN3_THYMOCYTE_VS_TCELL_LYMPHOMA_FROM_TCF1_KO_DN

DMXL2 SERPINF1 ENC1 LAMA5 SMC2 CREBL2 NEK2 SYNE2

3.19e-051991608M9423
CoexpressionGSE17721_CTRL_VS_PAM3CSK4_8H_BMDC_UP

RAD51 LUC7L3 MCM6 TRIM3 COG8 RNF167 ATG3 TUBGCP3

3.31e-052001608M3743
CoexpressionGSE3039_B2_VS_B1_BCELL_DN

OPN3 OLFM4 SLC39A4 CMSS1 GSTM4 GSTM5 HMGXB3 IQGAP3

3.31e-052001608M6453
CoexpressionGSE5589_WT_VS_IL6_KO_LPS_AND_IL10_STIM_MACROPHAGE_180MIN_UP

TDRD5 GSX1 HTR1B F2RL3 CDHR1 TAS1R2

3.91e-051021606M6681
ToppCellPBMC-Mild-cDC_12|Mild / Compartment, Disease Groups and Clusters

RAD51 DPY19L2 ABCC11 MCM6 SMC2 TFR2 RSPH10B2 TXNRD3 IQGAP3

3.10e-081891619946c95d2ecc36b241f58e8c4ad6455fe47c762fa
ToppCellE16.5-samps-Mesenchymal-Matrix_fibroblast-_fetal-Mature_Fibroblast_1|E16.5-samps / Age Group, Lineage, Cell class and subclass

VPS13C B4GALT1 MEOX2 GSTM2 BMP3 TGM2 MACF1 FGFR4

1.46e-071631618f1ec2625b52664308968b01d8e0275e1e0751480
ToppCelldroplet-Fat-SCAT-30m-Epithelial|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GABRP PCDHGA3 EPB41L3 LRRC1 PKD1 TXNRD3 DDX23 FGG

4.18e-0718716185fada3c5a58c1890029ccbfff2608b33f8cd2df7
ToppCelldroplet-Fat-SCAT-30m-Epithelial-nan|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GABRP PCDHGA3 EPB41L3 LRRC1 PKD1 TXNRD3 DDX23 FGG

4.18e-071871618766e808138fc2cd623c2e6d57fcb5c7378da0e03
ToppCelldroplet-Fat-SCAT-30m-Epithelial-epithelial_cell|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GABRP PCDHGA3 EPB41L3 LRRC1 PKD1 TXNRD3 DDX23 FGG

4.18e-071871618f49d06600060deeb2fc1b1da5b93496535f20104
ToppCell368C-Myeloid-Macrophage-SPP1+_Macrophage_2|368C / Donor, Lineage, Cell class and subclass (all cells)

POLR1A CAMK1D PAPLN WDPCP RLF PTPRJ PLEC

3.02e-06171161726b34dc069cc15b75a0c13cb8c5d81e074788160
ToppCellfacs-Brain_Myeloid-Cerebellum-3m-Myeloid-microglial_cell|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TMEM176A ABCC5 EPB41L3 PTPRJ MED12L MACF1 FGG

3.52e-0617516171ea6cf9da26601646f57fa14d558a5e9e1f0b345
ToppCellTCGA-Breast-Primary_Tumor-Breast_Carcinoma-Infiltrating_Ductal_Carcinoma-5|TCGA-Breast / Sample_Type by Project: Shred V9

RAD51 SHMT2 ABCC11 TMEM45B ANLN ABCC12 FGFR4

4.56e-0618216179e48d5b634603bc7a8d29290202a311457678328
ToppCellmild_COVID-19_(asymptomatic)-T/NK_proliferative|mild_COVID-19_(asymptomatic) / disease group, cell group and cell class (v2)

RAD51 SMC2 LCT NEK2 ANLN GSDMA IQGAP3

4.72e-061831617df8568751205313d149939ea2683097e3652a60b
ToppCell(5)_Epithelial_cells-(5)_Glands_duct|(5)_Epithelial_cells / Oesophagus cell shreds on cell class (v1) and cell subclass (v1)

THEMIS2 DUSP4 ENC1 TMEM176A ABCC6 BMP3 TGM2

5.26e-061861617219b1aeca17503244fabbb780bca58f22c7c0f27
ToppCellfacs-Marrow-KLS-24m-Hematologic-MPP_Fraction_A_+_HSC|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

F2RL3 SERPINF1 TMEM176A TFR2 GSTM2 GSTM5 TGM2

5.26e-061861617f14722ecc832794dc267bf3f9b8a13274c3addc1
ToppCellE18.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF1-AF1_mature|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

TMEM176A B4GALT1 MEOX2 GSTM2 TGM2 MACF1 FGFR4

7.40e-061961617617103f4a09e009fe96c28eb5e40505a4fd6dcf4
ToppCellE18.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF1|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

TMEM176A B4GALT1 MEOX2 GSTM2 TGM2 MACF1 FGFR4

7.40e-061961617db64ab27374f82553ee577aec056141170f3656f
ToppCell3'-GW_trimst-1.5-SmallIntestine-Mesenchymal-fibroblastic-Stromal_2_(CH25H+)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SLC22A15 TMEM176A LAMA5 PAPLN BMP3 PLXNA4 ABCC12

7.40e-0619616171bcae4e0a244af822e2b12b2026a2771316f107d
ToppCellBrain_organoid-organoid_Tanaka_cellReport-10w-Stem_cells-Neuroepithelial_cell|10w / Sample Type, Dataset, Time_group, and Cell type.

RAD51 MCM6 SMC2 NEK2 ANLN SYNE2 IQGAP3

8.45e-0620016178f8b8c225cdc79baf16fe04be89bdb65e404a055
ToppCellBrain_organoid-organoid_Tanaka_cellReport-10w-Stem_cells|10w / Sample Type, Dataset, Time_group, and Cell type.

RAD51 MCM6 SMC2 NEK2 ANLN SYNE2 IQGAP3

8.45e-062001617a1f48eca9efb4f3ec3c9ace20f8c9257dd72c4ed
ToppCellChildren_(3_yrs)-Immune-dendritic_cell-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

CAMK1D DUSP4 MCF2 INPP5F TFR2 NAV1

1.93e-0515216160769857f25da2e6169420818e61d65e33b7277b1
ToppCellTCGA-Mesothelium-Primary_Tumor-Mesothelioma-Biphasic-6|TCGA-Mesothelium / Sample_Type by Project: Shred V9

HTR1B PLEKHG2 ARHGEF40 SYT15B ANLN CDYL2

2.48e-05159161685501c636cd04f15ba1be24df1ba7ac909633ce8
ToppCell3'_v3-bone_marrow-Lymphocytic_B-Pre-B|bone_marrow / Manually curated celltypes from each tissue

TMEM8B SLC39A4 BMP3 FCRL1 NAV1 PGBD2

2.76e-051621616e088e66aabc307dde5d2b9aa295c34ef68155b1a
ToppCellPND28-Immune-Immune_Myeloid-DC-cDC1|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

POLR1A CAMK1D SERPINF1 FAM83F ASB2 IQGAP3

2.96e-0516416165638d95c7cc5e59c4a7bda30268a904a01861a5f
ToppCellNS-control-d_0-4-Myeloid-pDC|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

THEMIS2 OPN3 SFMBT2 GSTM1 PLXNA4 MED12L

3.06e-0516516168b2d43d7c4ee07bd999bd51bc15117ce1fbb2d86
ToppCellcontrol-Myeloid-pDC|control / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

THEMIS2 OPN3 SFMBT2 GSTM1 PLXNA4 MED12L

3.06e-051651616243c74adf8d993ff92acbff2768bdc5a1693eca3
ToppCell367C-Myeloid-Dendritic-cDC_proliferating_2|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

SMC2 TFR2 MEOX2 NEK2 ANLN IQGAP3

3.74e-0517116160eea035fde32cc2a75a0d4227911edb5d54ed47e
ToppCelldroplet-Lung-LUNG-30m-Myeloid-Proliferating_Dendritic|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RAD51 OPN3 DCSTAMP NEK2 ASB2 IQGAP3

3.99e-0517316166c9ecf77d2fb0f89100fdd7e4e88f85598278bc7
ToppCell(03)_Secretory-(0)_uninjured|(03)_Secretory / shred by cell type and Timepoint

SERPINF1 ENC1 SLC39A4 TRIM3 GSTM1 GSTM2

4.12e-051741616ebdddb5091afcc49ab533c890f260f709880c5f9
ToppCellfacs-Marrow-Granulocytes-3m-Myeloid-basophil|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HTR1B TMEM8B PAPLN SLC39A4 ITGA1 GSTM4

4.25e-0517516161b35acece23712ab7e3f92d9d68266efd38b3ef5
ToppCell367C-Myeloid-Dendritic-cDC_proliferating_2|Dendritic / Donor, Lineage, Cell class and subclass (all cells)

TFR2 MEOX2 NEK2 ANLN GSDMA IQGAP3

4.25e-051751616bde785ff0c854646d7ab8571359e9d69a7bf013f
ToppCellfacs-Tongue-nan-24m-Epithelial-basal_cell_of_epidermis|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TMEM176A SMC2 GSTM1 GSTM2 ASS1 IQGAP3

4.25e-051751616758a1796b823118ce52f989ef5e1076f8c8ac4c5
ToppCellfacs-Marrow-Granulocytes-3m-Myeloid-basophil|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HTR1B TMEM8B PAPLN SLC39A4 ITGA1 GSTM4

4.25e-051751616a9f88054e2c28d604c65ed785f63021aadb7f4c8
ToppCellE16.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF1-AF1_prolif|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MC3R TMEM176A MEOX2 GSTM1 GSTM2 MACF1

4.82e-051791616948c2a01ec7a626c68281e6e796a9f0527a88591
ToppCell10x_3'_v3-spleen_(10x_3'_v3)-hematologic-hematopoietic_progenitor|spleen_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

OLFM4 TFR2 GSTM5 ANLN MED12L PCDH8

4.97e-051801616f598bb9df0d784120847fada2d9a2a88b8b68cd1
ToppCell(05)_Ciliated-(4)_1wkpi|(05)_Ciliated / shred by cell type and Timepoint

CDHR1 SLC22A15 TGM2 NEK2 CFAP69 RSPH10B

4.97e-05180161685fc9b164147b28545e2397d32302eea03ef6346
ToppCell10x_3'_v3-spleen_(10x_3'_v3)-hematologic-hematopoietic_progenitor-hematopoietic_stem_cell|spleen_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

OLFM4 TFR2 GSTM5 ANLN MED12L PCDH8

4.97e-051801616b4fa047f271c7b56940bdc85c912f50aa5b5ca82
ToppCellP28-Endothelial-proliferative_endothelial_cell-proliferative_endothelial_cell|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

RAD51 MCM6 SMC2 NEK2 ANLN IQGAP3

5.13e-051811616e482fd116c00ff4d8db7be3c06b1bd1ffa2d479d
ToppCellP28-Endothelial-proliferative_endothelial_cell|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

RAD51 MCM6 SMC2 NEK2 ANLN IQGAP3

5.13e-0518116162be3d44619adb25d339e7a27b500a56e07e8de01
ToppCellfacs-Marrow-T-cells-3m-Myeloid|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HTR1B VPS13C LAMA5 ITGA1 ITGB7 FGG

5.13e-0518116167286700396676fdc41d9723979b8b408177aceb9
ToppCelldroplet-Marrow-nan-3m-Myeloid-promonocyte|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

VPS13C ITGA1 ITGB7 GSTM1 ASS1 PLEC

5.29e-051821616bc8d621be57f76d718d9b0f11e023b0f4dcb668d
ToppCelldroplet-Kidney-KIDNEY-30m-Epithelial-kidney_proximal_convoluted_tubule_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

APOB EPB41L3 GSTM5 FAM151A ASS1 FGG

5.45e-05183161692f54c267135cb5edbcacd26a0f29e62469bb7e5
ToppCelldroplet-Lung-LUNG-1m-Lymphocytic-Proliferating_T|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RAD51 F2RL3 MCM6 SMC2 NEK2 ASS1

5.45e-051831616769a022fe8568ec49e66f792cc5777e713a7571c
ToppCell(7)_DC_plasmacytoid|World / Spleen cell shreds - cell class (v1) and cell subclass (v1)

THEMIS2 TMEM8B SERPINF1 PAPLN NELL1 PLXNA4

5.45e-0518316162c6475c935b5a90931be6b3c53f1f707cfcd11f4
ToppCelldroplet-Kidney-KIDNEY-30m-Epithelial-Epcam____kidney_proximal_convoluted_tubule_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

APOB EPB41L3 GSTM5 FAM151A ASS1 FGG

5.45e-0518316165c4f7d02ba3a3c4a22ac71302e7c9a47e205eef5
ToppCell10x_3'_v2v3-Non-neoplastic-Myeloid-TAM-MG-TAM-MG_pro-infl_I-E|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

THEMIS2 SERPINF1 TMEM176A GSTM2 WDR91 IER5L

5.45e-051831616614a1c08cf6d01a4f1ed2fb816cd1a6e0c3207ce
ToppCelldroplet-Lung-LUNG-1m-Lymphocytic-T_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RAD51 F2RL3 MCM6 SMC2 NEK2 ASS1

5.45e-051831616aac0695fafa59cabd920ee18b1139d3e00d898e8
ToppCelldroplet-Lung-1m-Hematologic-lymphocytic-Proliferating_T_cell|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

RAD51 F2RL3 MCM6 SMC2 NEK2 ASS1

5.79e-0518516160e0f043ad6d2a62cd47ce39911ad81feab4a4d7e
ToppCelldroplet-Lung-1m-Hematologic-lymphocytic-Proliferating_T_cell-proliferating_T|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

RAD51 F2RL3 MCM6 SMC2 NEK2 ASS1

5.79e-05185161689b85ce8026dc80c1bd9f76dfe16401c173b7946
ToppCellfacs-Lung-EPCAM-24m-Epithelial-Club_Cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RAD51 GABRP DUSP4 NEK2 TMEM45B FAM83F

6.14e-05187161674112df9b34051ae5cd2427ccfa3399eccff0076
ToppCellfacs-Bladder|facs / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DUSP4 GSTM1 GSTM2 GSTM4 BMP3 TMEM45B

6.14e-051871616dd5ca59417fd1b388fd975f0f3e1f3245d66ebc5
ToppCellfacs-Lung-EPCAM-24m-Epithelial-club_cell_of_bronchiole|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RAD51 GABRP DUSP4 NEK2 TMEM45B FAM83F

6.14e-051871616214ce9b55fd6ce2fe7bd4cf4b1383517f5f0d759
ToppCellFetal_29-31_weeks-Immune-interstitial_macrophage_(C1Q_positive)-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

THEMIS2 DMXL2 PLEKHG2 EPB41L3 SNX6 SLC49A4

6.33e-0518816163be2d50148daa4eddddc2c7f269f45c97f7e4931
ToppCellnucseq-Immune-Immune_Myeloid-Myeloid_Dendritic-cDC1|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

DUSP4 SERPINF1 INPP5F ATG3 MED12L ASB2

6.33e-051881616d5ce3ffe783c322b4765b790e861727e46bc34b3
ToppCellMultiple_Sclerosis-Lymphocyte-T_NK-T_NK_proliferative|Multiple_Sclerosis / Disease, Lineage and Cell Type

RAD51 MCM6 SMC2 NEK2 ANLN IQGAP3

6.33e-0518816166c05797a5d0635d89ffcf4aca52178687129ccb4
ToppCellfacs-Marrow-KLS-24m-Hematologic|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

F2RL3 SERPINF1 TMEM176A TFR2 GSTM1 GSTM5

6.33e-051881616e1f18c11e4848978ca7bbe9271917da14b3f0523
ToppCellfacs-Marrow-KLS-24m-Hematologic-hematopoietic_stem_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

F2RL3 SERPINF1 TMEM176A TFR2 GSTM1 GSTM5

6.33e-051881616283a7a22db144e8f942904d4a38cac30874f6d9e
ToppCellBAL-Severe-Myeloid-cDC-cDC-cDC_0|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

CAMK1D SYT3 SERPINF1 TMEM176A EPB41L3 NAV1

6.33e-0518816169fc3819aae5a2b2534cb131d467435b5cfc420d6
ToppCellBAL-Severe-Myeloid-cDC-cDC-cDC_0|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

CAMK1D SYT3 SERPINF1 TMEM176A EPB41L3 NAV1

6.33e-0518816165e5d779ea079d3b2a1ef650b06b9f5cc1ffef5e7
ToppCellnormal-na-Lymphocytic|normal / PBMC cell types (v2) per disease, treatment status, and sex

RAD51 MCM6 SMC2 LCT NEK2 ANLN

6.52e-0518916161d382f8eb998c6a30e09fddc9a427afc8f5f7323
ToppCellnormal-na-Lymphocytic-lymphocyte|normal / PBMC cell types (v2) per disease, treatment status, and sex

RAD51 MCM6 SMC2 LCT NEK2 ANLN

6.52e-051891616b83fd81ecc5ef363be7435ee12cb7079e2434af7
ToppCellDividing_Macrophages-SSc-ILD_02|World / lung cells shred on cell class, cell subclass, sample id

RAD51 SMC2 GSTM1 NEK2 ANLN IQGAP3

6.52e-051891616d4e88a3e50499d683e3db38aee04490146fe30bb
ToppCellfacs-Marrow-KLS|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

F2RL3 SERPINF1 TMEM176A SHMT2 MCM6 TFR2

6.52e-0518916164214abfa07b047e256df43e472f9a835a18ed7a3
ToppCellnormal-na-Lymphocytic-lymphocyte-female|normal / PBMC cell types (v2) per disease, treatment status, and sex

RAD51 MCM6 SMC2 LCT NEK2 ANLN

6.52e-0518916163db4177d68cab4cd16842d2ebcaca28f69300e44
ToppCellInt-URO-Lymphocyte-T_NK-T_NK_proliferative|Int-URO / Disease, Lineage and Cell Type

RAD51 CDHR1 MCM6 SMC2 NEK2 IQGAP3

6.71e-051901616005967c540418b85311308072a07c684f4296aef
ToppCell(02)_Cycling_Basal_(regeneration)|World / shred by cell type and Timepoint

RAD51 SHMT2 MCM6 SMC2 ANLN IQGAP3

6.71e-05190161653f017a11ca5ebe9025558e12cedc409cab2e5aa
ToppCellPBMC-Severe-Myeloid-Neutrophil-Neutrophil-Neu_4|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

ARHGEF40 ANLN PAN2 POFUT2 IQGAP3 LRRC23

6.71e-0519016163f0c7d130f66faea778fe567604edf1b4cdf85b3
ToppCelldroplet-Lung-3m-Mesenchymal-fibroblast-alveolar_fibroblast|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

TMEM176A MEOX2 GSTM1 GSTM2 MACF1 FGFR4

6.91e-051911616509230f50568e5a8ecf08edc4d58f9e2aa96efe9
ToppCell(011)_pDC|World / immune cells in Peripheral Blood (logTPM normalization)

TMEM8B OPN3 SERPINF1 PAPLN NELL1 PLXNA4

6.91e-051911616d82ac4f6d9863734e09bf3cb71c1354a49b66b4f
ToppCell(01)_Dendritic_cell|World / immune cells in Peripheral Blood (logTPM normalization)

TMEM8B OPN3 SERPINF1 NELL1 PLXNA4 NAV1

6.91e-0519116161f4c8078e1a6cd14937c714330af608caced2acf
ToppCellE16.5-samps-Mesenchymal-Matrix_fibroblast-_fetal|E16.5-samps / Age Group, Lineage, Cell class and subclass

TMEM176A B4GALT1 MEOX2 GSTM2 BMP3 MACF1

6.91e-0519116163379d145d34f89150f7b06d1340022cfc6b4a6ce
ToppCellPND01-03-samps-Mesenchymal-Matrix_fibroblast-MatrixFB-A|PND01-03-samps / Age Group, Lineage, Cell class and subclass

TMEM176A B4GALT1 MEOX2 BMP3 MACF1 FGFR4

6.91e-051911616e7c605b56934d1383237c1f946dbccef25d91368
ToppCellsaliva-Mild-Moderate_progression_d12-25-Myeloid-Dendritic-conventional_dendritic_cell-DC_c2-CD1C|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

HK1 OPN3 EPB41L3 GSTM4 ADPRH ASB2

6.91e-0519116165c0c44612b4cdbf89c0f1f219416374a7541f610
ToppCellfacs-Marrow-KLS-3m-Hematologic-MPP_Fraction_A_+_HSC|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

F2RL3 SERPINF1 TMEM176A TFR2 GSTM5 TGM2

7.11e-051921616959c28d28397bc0b9d3970d1fe3293d2750e63d4
ToppCellLPS_only-Stromal_mesenchymal-Matrix_Fibroblast-Activated_MatrixFB|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SERPINF1 PAPLN MEOX2 NELL1 PLXNA4 CFAP69

7.11e-051921616df1545670370fb1010c567cd059c2783eab315f7
ToppCellPBMC-Severe-Myeloid-Neutrophil-Neutrophil-Neu_4|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

ARHGEF40 ANLN PAN2 POFUT2 IQGAP3 LRRC23

7.11e-051921616c09dcc73ff9c3855a0f3d7bfa0d5c99c09a117f2
ToppCellSmart-start-Cell-Wel_seq-Neoplastic-Stem-like-OPC-like-OPC-like-F|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

OLFM4 DCST2 FAM151A MROH2B ABCC12 USH2A

7.31e-051931616315840bc48899f3a36d57b19197509de19716e3d
ToppCellASK440-Epithelial-Secretory|ASK440 / Donor, Lineage and Cell class of Lung cells from Dropseq

GABRP SERPINF1 ABCC5 SYNE2 LRRC1 ASS1

7.31e-05193161650e98d91697c7af6a3de39e52edde6dd2b67b512
ToppCell343B-Epithelial_cells-Epithelial-G_(Club-Clara_cells)-|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

GABRP DUSP4 SERPINF1 TMEM176A TGM2 ASB2

7.31e-0519316168ede7038a222c7e7ecaf7e86520823cf606cbee7
ToppCell343B-Epithelial_cells-Epithelial-G_(Club-Clara_cells)|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

GABRP DUSP4 SERPINF1 TMEM176A TGM2 ASB2

7.31e-0519316160e7d7adfaa7191e34038fcda6677561ae13934eb
ToppCellE17.5-Mesenchymal-mesenchymal_fibroblast|E17.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

TMEM176A B4GALT1 MEOX2 TGM2 MACF1 FGFR4

7.53e-051941616f15e81ff12525523c62d13105cf264ea72205e2e
ToppCellFetal_29-31_weeks-Immune-alveolar_macrophage_(MARCO_positive)-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

THEMIS2 DMXL2 PLEKHG2 EPB41L3 TRABD SLC49A4

7.53e-0519416163043f6230fa723037c8cf7123f611ae847b39fd4
ToppCellP03-Endothelial-proliferative_endothelial_cell|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

RAD51 MCM6 SMC2 NEK2 ANLN IQGAP3

7.53e-05194161622bcfb0f3f73608feb22c0847ab4d34f87aeede0
ToppCellP03-Endothelial-proliferative_endothelial_cell-proliferative_endothelial_cell|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

RAD51 MCM6 SMC2 NEK2 ANLN IQGAP3

7.53e-0519416165e56ce9b9fe0721be3a9e6efe1422599bb867721
ToppCell(7)_Epithelial_cells-(7)_Epithelial-J_(AT1-AT2_progenitors)|(7)_Epithelial_cells / Lung cell shreds - cell class (v4) and cell subclass (v4)

RAD51 MCM6 SMC2 NEK2 ANLN IQGAP3

7.53e-0519416164d6ae2b25db11a4ae6dadee83be5c8c05b1225c3
ToppCellcontrol-Myeloid-Immature_Neutrophils_2|Myeloid / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

RAD51 OLFM4 MCM6 SMC2 ANLN IQGAP3

7.74e-051951616bfaceb0601cf3855f38d6e1f482f01ad03ef11fe
ToppCellE17.5-Mesenchymal-mesenchymal_fibroblast-alveolar_fibroblast_Wnt2-pa|E17.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

TMEM176A B4GALT1 MEOX2 TGM2 MACF1 FGFR4

7.74e-051951616b072fdc2131173f562e55dd78226eaf2c57d3690
ToppCell3'_v3-bone_marrow-Lymphocytic_T_CD4-T_CD4/CD8|bone_marrow / Manually curated celltypes from each tissue

DUSP4 APOB SYT15B SYNE2 MACF1

7.84e-05121161519333a660800b583fa27b495c1f7828e6636a257
ToppCellPND01-03-samps-Mesenchymal-Matrix_fibroblast|PND01-03-samps / Age Group, Lineage, Cell class and subclass

TMEM176A B4GALT1 MEOX2 BMP3 MACF1 FGFR4

7.96e-05196161654f4cf778f95a9ff662e5c7520916a25e605bf95
ToppCellcycling_basal_cell|World / shred by cell class for nasal brushing

RAD51 MCM6 SMC2 NEK2 ANLN IQGAP3

7.96e-051961616aa7bac70a2fe4a3cb28d89fa1a87c68c2ead1349
ToppCellE18.5-Mesenchymal-Mesenchymal_structural|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

TMEM176A MEOX2 GSTM2 TGM2 MACF1 FGFR4

7.96e-05196161697e26622d9582b092c18ff5b7e957818f99d9631
ToppCellE18.5-Mesenchymal-Mesenchymal_structural-Fibroblastic|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

TMEM176A MEOX2 GSTM2 TGM2 MACF1 FGFR4

7.96e-051961616f429f045ba45e24717963315832150b12a115bfa
ToppCellParenchymal-NucSeq-Immune_Myeloid-Macrophage_alveolar-Macro_alv_dividing|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

THEMIS2 SMC2 FCRL1 ANLN BRINP2 IQGAP3

8.19e-051971616d669d90c3f9e98b41bcbc49dbdc5698e0b42597c
ToppCellmild-Myeloid-Immature_Neutrophils_2|Myeloid / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

RAD51 MCM6 SMC2 NEK2 ANLN IQGAP3

8.19e-051971616bd9d57e0c873f6526dca322f4dad8e6bd692586c
ToppCellsevere-Myeloid-Immature_Neutrophils_2|severe / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

RAD51 OLFM4 MCM6 SMC2 ANLN IQGAP3

8.42e-051981616844f534551483c89ef789d1cfeb4680e54f794b2
ToppCellImmune_cells-large_pre-B.|Immune_cells / Lineage and Cell class

RAD51 SHMT2 MCM6 CMSS1 SMC2 TXNRD3

8.42e-051981616bc9ceefadb153907d2854d1f736d17349003cb31
ToppCellcycling_basal_cell|World / shred by cell class for turbinate

RAD51 MCM6 SMC2 NEK2 ANLN IQGAP3

8.42e-051981616e86c1224f5b0890a50a25257628e90c790aae7cd
ToppCellSevere-B_intermediate-6|World / disease group and sub_cluster of B and Plasma cells(res = 0.5)

THEMIS2 DUSP4 ENC1 ITGB7 B4GALT1 PTPRJ

8.42e-0519816168402421dc060926e968efe39a4e907f1e8ae5b1f
ToppCellproximal-mesenchymal-Alveolar_Fibroblast|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

TMEM176A MEOX2 GSTM5 TGM2 MACF1 FGFR4

8.66e-0519916167f4840ae6a888380feca722543e5e52783f3e35d
ToppCellproximal-3-mesenchymal-Alveolar_Fibroblast|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

TMEM176A MEOX2 GSTM5 TGM2 MACF1 FGFR4

8.66e-051991616301d02bbb37e6f1d24b6e865bc3fe3e91260eb30
ToppCell18-Airway-Mesenchymal-Mesenchyme_RSPO2+|Airway / Age, Tissue, Lineage and Cell class

MEOX2 NEK2 ANLN MACF1 FGFR4 IQGAP3

8.66e-0519916167ac35e8f45dcdc702422dabd8f3e4d03e2bf61af
ToppCell3'_v3-lymph-node_spleen-Lymphocytic_T_CD4/8-lo-Cycling_T|lymph-node_spleen / Manually curated celltypes from each tissue

RAD51 DUSP4 MCM6 SMC2 NEK2 ANLN

8.66e-05199161628fc342d2d178ce33203a78eb9eedae54fa9c916
ToppCellproximal-mesenchymal-Alveolar_Fibroblast-3|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

TMEM176A MEOX2 GSTM5 TGM2 MACF1 FGFR4

8.66e-0519916169a16e519fb0651a7c4d8e05b931df4fb3b0eb3d1
ToppCell(5)_Fibroblast-G|World / Lung cell shreds - cell class (v4) and cell subclass (v4)

MEOX2 GSTM5 NELL1 TGM2 MACF1 FGFR4

8.66e-051991616b4a737575be9f8c65771832dd8cd25328d5dae0d
ComputationalROS metabolism.

GSTM1 GSTM2 GSTM4 GSTM5

2.62e-0522874MODULE_310
ComputationalGenes in the cancer module 101.

GSTM2 GSTM4 GSTM5

5.90e-0510873MODULE_101
ComputationalGenes in the cancer module 132.

GSTM2 GSTM4 GSTM5

1.75e-0414873MODULE_132
DrugEthoxyquin

ABCC5 ABCC6 GSTM1 GSTM2 GSTM4 GSTM5

3.21e-07401586ctd:D005015
DrugEUK-189

GSTM1 GSTM2 GSTM4 GSTM5

3.81e-06161584ctd:C436526
Drugoxidized glutathione

HK1 ABCC5 GSX2 SMC2 ABCC6 GSTM1 GSTM2 GSTM4 GSTM5 TXNRD3

4.40e-0622715810CID000000975
DrugClch2cosg

GSTM1 GSTM2 GSTM4 GSTM5

6.33e-06181584CID000163913
DrugC14791

GSTM1 GSTM2 GSTM4 GSTM5

6.33e-06181584CID011954044
DrugC14793

GSTM1 GSTM2 GSTM4 GSTM5

6.33e-06181584CID011954046
DrugC14803

GSTM1 GSTM2 GSTM4 GSTM5

6.33e-06181584CID011954054
DrugC14805

GSTM1 GSTM2 GSTM4 GSTM5

6.33e-06181584CID011954056
DrugC14804

GSTM1 GSTM2 GSTM4 GSTM5

6.33e-06181584CID011954055
DrugC14806

GSTM1 GSTM2 GSTM4 GSTM5

6.33e-06181584CID011954057
DrugC14848

GSTM1 GSTM2 GSTM4 GSTM5

6.33e-06181584CID011954067
DrugC14856

GSTM1 GSTM2 GSTM4 GSTM5

6.33e-06181584CID011954069
DrugC14855

GSTM1 GSTM2 GSTM4 GSTM5

6.33e-06181584CID011954068
DrugS-(2,2-dichloro-1-hydroxy)ethylglutathione

GSTM1 GSTM2 GSTM4 GSTM5

6.33e-06181584CID011954070
DrugAC1L4MYY

GSTM1 GSTM2 GSTM4 GSTM5

6.33e-06181584CID000188517
Drug1-chloro-2,4-dinitrobenzene-glutathione conjugate

GSTM1 GSTM2 GSTM5

6.46e-0661583ctd:C042630
Drug2-(S-glutathionyl) acetyl glutathione

GSTM1 GSTM2 GSTM4 GSTM5

9.92e-06201584CID011954072
DrugC14865

GSTM1 GSTM2 GSTM4 GSTM5

9.92e-06201584CID011954073
DrugS-(formylmethyl)glutathione

GSTM1 GSTM2 GSTM4 GSTM5

2.13e-05241584CID011954074
Drugglutathione reduced

GSX1 HK1 ABCC5 ABCC11 GSX2 SMC2 ITGB7 ABCC6 GSTM1 GSTM2 GSTM4 GSTM5 TGM2 ABCC12

2.25e-0553415814CID000000745
DrugAC1Q608X

GSTM1 GSTM2 GSTM4 GSTM5

4.01e-05281584CID000128466
DrugAC1L33DC

GSTM1 GSTM2 GSTM4 GSTM5

4.01e-05281584CID000133757
Drugoltipraz

ABCC5 ABCC6 GSTM1 GSTM2 GSTM4

4.34e-05561585ctd:C026209
Drug2-BHA

GSTM1 GSTM2 GSTM4 GSTM5

4.63e-05291584CID000006932
DrugGlutathione S-(2,4 Dinitrobenzene)

GSTM1 GSTM2

4.79e-0521582DB02458
Drugoltipraz

ABCC5 ABCC6 GSTM1 GSTM2 GSTM4 GSTM5 PLEC

4.91e-051371587CID000047318
Drugethacrynic acid

ABCC5 ABCC6 GSTM1 GSTM2 GSTM4 GSTM5 ABCC12

5.14e-051381587CID000003278
DrugDcvg

GSTM1 GSTM2 GSTM4 GSTM5

6.07e-05311584CID006437359
Drugo-dinitrobenzene

GSTM1 GSTM2 GSTM4 GSTM5

6.07e-05311584CID000010707
DrugPenCB

LCT GSTM1 GSTM2 GSTM4 GSTM5

6.57e-05611585CID000036188
Drug6-Hydroxytropinone [5932-53-6]; Up 200; 25.8uM; MCF7; HT_HG-U133A

DMXL2 CAMK1D MAP3K6 TRIM3 GNB5 TUBGCP3 PDCD11 ZNF654

6.99e-0519615884833_UP
Drugsulfobromophthalein

ABCC5 ABCC6 GSTM1 GSTM2 GSTM4 GSTM5

8.34e-051031586CID000005345
Drugss,ss-carotene

PCDHGA10 PCDHGA3 APOB GSTM1 GSTM2 GSTM4 GSTM5 TGM2

8.34e-052011588CID000000573
Drugm-toluidine

GSTM1 GSTM2 GSTM4 GSTM5

8.80e-05341584CID000007934
DrugLyndiol

GSTM1 GSTM2 GSTM4 GSTM5

8.80e-05341584CID000082149
DrugAC1NSK22

RARS1 GSTM1 GSTM2 GSTM4 GSTM5

9.60e-05661585CID005311131
Drugdimethoxystrychnine

GSTM1 GSTM2 GSTM4 GSTM5

9.89e-05351584CID000009649
DrugDixan

GSTM1 GSTM2 GSTM4 GSTM5

9.89e-05351584CID000010404
DrugGlutathione

GSTM1 GSTM2 GSTM4 GSTM5

1.11e-04361584DB00143
DrugCAS 81-11-8

APOB LCT GSTM1 GSTM2 GSTM4 GSTM5

1.20e-041101586CID000006668
DiseaseBrugada syndrome (implicated_via_orthology)

GSTM1 GSTM2 GSTM4 GSTM5

3.65e-0951554DOID:0050451 (implicated_via_orthology)
Diseasemental development measurement

PCDHGA10 PCDHGA5 PCDHGA3 PCDHGA1

8.50e-06251554EFO_0008230
Diseaselevel of glutathione S-transferase mu 1 in blood serum

GSTM1 GSTM2

2.74e-0521552OBA_2041806
Disease3,7-dimethylurate measurement

GSTM2 GSTM5

2.74e-0521552EFO_0800949
Diseasechildhood trauma measurement, alcohol consumption measurement

PCDHGA10 PCDHGA5 PCDHGA3 PCDHGA1 SFMBT2

3.69e-05711555EFO_0007878, EFO_0007979
DiseaseDegenerative Diseases, Central Nervous System

GSTM1 GSTM2 GSTM4 GSTM5

5.22e-05391554C0270715
DiseaseNeurodegenerative Disorders

GSTM1 GSTM2 GSTM4 GSTM5

5.22e-05391554C0524851
DiseaseDegenerative Diseases, Spinal Cord

GSTM1 GSTM2 GSTM4 GSTM5

5.22e-05391554C0751733
Diseaseobesity (implicated_via_orthology)

HK1 MC3R GSTM1 GSTM2 GSTM4 GSTM5 MED12L

1.48e-042151557DOID:9970 (implicated_via_orthology)
DiseaseSarcosine measurement

PCDHGA5 PCDHGA3 PCDHGA1

2.33e-04231553EFO_0021668
Diseaseglutathione S-transferase Mu 1 measurement

GSTM2 GSTM5

2.71e-0451552EFO_0801638
Diseaseerythrocyte aggregation

SFMBT2 NELL1

4.06e-0461552EFO_0803375
Diseaseoral squamous cell carcinoma (is_implicated_in)

GSTM1 BRINP2 FGFR4

4.23e-04281553DOID:0050866 (is_implicated_in)
DiseaseD dimer measurement

PTPRJ FGG CATSPERG

5.20e-04301553EFO_0004507
Diseaseanxiety, vitamin D measurement

GNB5 SEMA3E

5.66e-0471552EFO_0004631, EFO_0005230
Diseaseobsolete_red blood cell distribution width

THEMIS2 HK1 KMT2B POLR1A PCDHGA5 ENC1 ABCC5 PAPLN MCM6 APOB TFR2 NEK2 METTL25B IER5L ANLN SYNE2 LRRC23

7.49e-04134715517EFO_0005192
Diseaselactase-phlorizin hydrolase measurement

MCM6 LCT

7.52e-0481552EFO_0801753
Diseasebenign neoplasm (implicated_via_orthology)

LRRC1 SCRIB

7.52e-0481552DOID:0060072 (implicated_via_orthology)
Diseasecolorectal adenocarcinoma (is_implicated_in)

KMT2B GSTM1 FAM151A

8.22e-04351553DOID:0050861 (is_implicated_in)
Diseasevesicoureteral reflux

HTR1B WDPCP CATSPERG

1.05e-03381553EFO_0007536
Diseaseretinitis pigmentosa (is_implicated_in)

HK1 SERPINF1 USH2A

1.31e-03411553DOID:10584 (is_implicated_in)
Diseasekidney cancer (implicated_via_orthology)

LRRC1 SCRIB

1.46e-03111552DOID:263 (implicated_via_orthology)
Diseaseurate measurement, bone density

GABRP LUC7L3 LAMA5 SFMBT2 FBXL4 NELL1 ASS1 PLXNA4 NAV1 USH2A

1.67e-0361915510EFO_0003923, EFO_0004531
Diseaseesophagus squamous cell carcinoma (is_implicated_in)

EPB41L3 GSTM1 FGFR4

1.72e-03451553DOID:3748 (is_implicated_in)
Diseaselymphocyte count

THEMIS2 PCDHGA10 OPN3 PCDHGA5 PCDHGA3 PCDHGA1 ENC1 OLFM4 ABCC5 GSX2 ITGA1 ITGB7 TFR2 PTPRJ MED12L PLEC PGBD2

1.84e-03146415517EFO_0004587
Diseaseosteitis deformans

DCSTAMP GSTM5

2.06e-03131552EFO_0004261
Diseaseapolipoprotein B to apolipoprotein A1 ratio

APOB GSTM1 GSTM2

2.19e-03491553EFO_0021897
Diseasediabetic retinopathy (is_implicated_in)

SERPINF1 APOB GSTM1

2.33e-03501553DOID:8947 (is_implicated_in)
Diseasedystonia (is_implicated_in)

KMT2B NUP54

2.39e-03141552DOID:543 (is_implicated_in)
Diseasefemoral neck bone geometry

UMOD FGFR4

2.39e-03141552EFO_0004511
Diseaseapolipoprotein B measurement

HK1 DUSP4 APOB ITGA1 TFR2 GSTM1 GSTM2 GSTM5 SYNE2 PLEC

2.74e-0366315510EFO_0004615
Diseasealkaline phosphatase measurement

ATP13A1 TMEM176A PAPLN SLC39A4 APOB ITGA1 TULP2 WDR91 PTPRJ PKD1 CDYL2 GSDMA MACF1

2.79e-03101515513EFO_0004533
Diseasemean platelet volume

DIS3L PCDHGA10 PCDHGA5 PCDHGA3 PCDHGA1 ABCC5 GSTM1 GSTM2 PTPRJ TRABD SYNE2 PLEC CATSPERG

2.91e-03102015513EFO_0004584
Diseasephospholipids in medium HDL measurement

APOB GSTM1 GSTM2

3.05e-03551553EFO_0022295
DiseaseDiabetic Angiopathies

SERPINF1 ASS1

3.13e-03161552C0011875
DiseaseMicroangiopathy, Diabetic

SERPINF1 ASS1

3.13e-03161552C0025945
Diseasefree cholesterol to total lipids in large HDL percentage

APOB GSTM1 GSTM2

3.21e-03561553EFO_0022279
DiseaseDystonia, Limb

KMT2B SERAC1

3.54e-03171552C0751093
DiseaseDystonia, Diurnal

KMT2B SERAC1

3.54e-03171552C0393610
Diseaselow density lipoprotein particle size measurement

APOB GSTM1 GSTM2

3.55e-03581553EFO_0008593
Diseasetotal lipids in medium HDL measurement

APOB GSTM1 GSTM2

3.55e-03581553EFO_0022310
Diseasefree cholesterol in medium HDL measurement

APOB GSTM1 GSTM2

3.55e-03581553EFO_0022267
Diseasemultiple myeloma (is_implicated_in)

HK1 GSTM1 FGG

3.73e-03591553DOID:9538 (is_implicated_in)
Diseasecholesterol in medium HDL measurement

APOB GSTM1 GSTM2

3.73e-03591553EFO_0021903
DiseaseDystonia, Paroxysmal

KMT2B SERAC1

3.97e-03181552C0393588
Diseasephospholipids in HDL measurement

APOB GSTM1 GSTM2

4.09e-03611553EFO_0022293
Diseasediet measurement, HOMA-B

CREBL2 PLXNA4

4.42e-03191552EFO_0004469, EFO_0008111
Diseaseoptic disc size measurement

GSX2 CMSS1 BMP3 NAV1 MACF1

4.65e-032051555EFO_0004832
DiseaseSarcomatoid Renal Cell Carcinoma

GSTM1 TGM2 SYNE2 SLC49A4

4.72e-031281554C1266043
DiseaseChromophobe Renal Cell Carcinoma

GSTM1 TGM2 SYNE2 SLC49A4

4.72e-031281554C1266042
DiseaseCollecting Duct Carcinoma of the Kidney

GSTM1 TGM2 SYNE2 SLC49A4

4.72e-031281554C1266044
DiseasePapillary Renal Cell Carcinoma

GSTM1 TGM2 SYNE2 SLC49A4

4.72e-031281554C1306837
DiseaseRenal Cell Carcinoma

GSTM1 TGM2 SYNE2 SLC49A4

4.72e-031281554C0007134

Protein segments in the cluster

PeptideGeneStartEntry
FYIRIYSRDSSELLE

TDRD5

486

Q8NAT2
KRLAFDITYTLEYSR

CATSPERG

886

Q6ZRH7
ALYGRIYVEARSRIL

HTR1B

226

P28222
SADLVHYLRLSRDYL

B3GALT6

221

Q96L58
VTLVYYLAGRDLSRL

B4GALT1

36

P15291
LRLYDRYSTVQAART

BMP3

61

P12645
ATLDYERSRTHYITV

CDHR1

196

Q96JP9
VTLTISAARLYYYRD

APOBEC3D

126

Q96AK3
VERTYREDALRYTLD

ARHGEF40

36

Q8TER5
LDYRRYAETLFDILV

BZW1

61

Q7L1Q6
LYEDRRSSALYFAVV

ASB2

406

Q96Q27
FLSLVYLYREAQARS

ATP13A1

1066

Q9HD20
ARYVRTDYTLLDVLE

GSDMA

51

Q96QA5
GSIRYNYLLDVLERS

FGFR4

231

P22455
DYYSSRRLVIELEEL

CMSS1

101

Q9BQ75
TFLLRTYAYLENRVR

TENT2

291

Q6PIY7
LYALLAADQDTSYRI

DMXL2

1431

Q8TDJ6
SRVYELRNEIYIFLV

FAM200A

311

Q8TCP9
ALYEDRYLLGTSLAR

ASS1

81

P00966
EDAILQTRTYDLYIT

ATG3

191

Q9NT62
YALLIVDSATALYRT

RAD51

216

Q06609
RLYDLRADREVAIYS

GNB5

306

O14775
YYHLLTTRDLDREET

PCDHGA5

401

Q9Y5G8
IIAGTSAYARLIDYA

SHMT2

221

P34897
YAVLRNITELRRIYS

RSPH10B

411

P0C881
YAVLRNITELRRIYS

RSPH10B2

411

B2RC85
SLLLDVEDYERRYLL

PATL1

531

Q86TB9
SIEDARTALQLYRKY

PAN2

1136

Q504Q3
ESIDRVYSLDDIRRY

MCM6

561

Q14566
TTDLLINFRYLVRDY

PTPRJ

1211

Q12913
TANLREYARYVLRTI

MED12L

1236

Q86YW9
YDRIIDRTNTTLYIV

NEK2

71

P51955
DYEYVILNILRFRTD

NEMF

126

O60524
AIRLLLEYTDSSYVE

GSTM5

16

P46439
DRDLLYSIDAYRSQR

ANLN

666

Q9NQW6
AIVSLIYIERLVSYA

CCNYL2

211

Q5T2Q4
RLLSVAERSYYLEKA

HMGXB3

81

Q12766
LLSYRDVQDYSAIIE

MAP3K6

281

O95382
YLSRLRRIEIATYLN

GSX2

226

Q9BZM3
LLRSYIHLRYVDISE

LRRC23

86

Q53EV4
ERSGVEYRLLQAAYL

PLXNA4

301

Q9HCM2
SIDSYYRLVIHRALD

PCDHGA10

401

Q9Y5H3
IYALRSFDYETLRQL

PCDH8

561

O95206
RQLRLSIDYALTGSY

EFR3B

341

Q9Y2G0
AAVDYLLYRLIFSVS

DCSTAMP

311

Q9H295
SIRLLLEYTDSSYEE

GSTM2

16

P28161
YLSRLRRIEIATYLN

GSX1

171

Q9H4S2
RISLARAVYSDRQIY

ABCC11

641

Q96J66
YEEALELAAYVRRLE

COG8

171

Q96MW5
NYYVRLIDTLLAASI

LCT

1471

P09848
YERDFLRYLQSLLAE

LUC7L3

81

O95232
ELREYYRLLSVLHSQ

TUBGCP3

331

Q96CW5
ALRRILRGEELTYDY

KMT2B

2676

Q9UMN6
YLTRLRRYEIAVNLD

MEOX2

211

P50222
LTRVLALYRSILDAY

METTL25B

21

Q96FB5
ARRTSIYHYLFEIVE

ANKRD49

216

Q8WVL7
AYYEAALLQLRVTEA

LAMA5

1016

O15230
SSELLYIYGALDSRV

MTPAP

336

Q9NVV4
AARILRYTDFDTLIY

DPY19L2

461

Q6NUT2
DVLENRYLVLSRCTY

DDX23

531

Q9BUQ8
RYLVLSRCTYVVLDE

DDX23

536

Q9BUQ8
YEADLQYRVTLDSLR

ITGA1

716

P56199
IRTHYDRLVDEYSLN

HK1

721

P19367
YIIYFLLESSRVLDN

GPR52

281

Q9Y2T5
YASSRREAYLLLQLF

IQGAP3

996

Q86VI3
LESSGLRDEIRYHYI

NELL1

116

Q92832
IYRYARSLEELLLDA

LRRC1

31

Q9BTT6
YEAISLLNSERYARL

MACF1

5761

Q9UPN3
GLVLAYRLSVEIYDR

ITGB7

741

P26010
AVRSEERYYIDADLL

NUP54

446

Q7Z3B4
YGSVLLLAAVSLDRY

F2RL3

161

Q96RI0
YYRLVTATSLDREQI

PCDHGA3

401

Q9Y5H0
TIYYLARLLEADCRV

P2RY4

266

P51582
YAAARRVLGYDLLEL

MCAT

91

Q8IVS2
ARALYSDRSIYILDD

ABCC5

696

O15440
TLTVLAYERYIRVVH

OPN3

131

Q9H1Y3
ILTHDSSIRYLQEIY

FGG

126

P02679
STILEYRDQISKYAR

WDPCP

561

O95876
ALLRSEYQADYESLR

APOB

1596

P04114
LEVTARAITYYLDVS

HECTD1

71

Q9ULT8
YLRYQEALSELATAV

C1orf43

176

Q9BWL3
RLEVNSSLLEYYTEL

FBXL4

206

Q9UKA2
LAARAVDRTRVYYRL

FAM151A

556

Q8WW52
IYSRLRKANITDVDY

FCRL1

411

Q96LA6
LCFRESYDRLYLDVV

SLC49A4

461

Q96SL1
YFALALEEQYSISRL

FRMPD1

221

Q5SYB0
LIERYAINIYLSDRI

GALNT4

96

Q8N4A0
EARTRATTYYLADRR

DIS3L

521

Q8TF46
ALRLREENRLYASYV

CCDC166

66

P0CW27
LRYQYLEELVSSRER

CREBL2

46

O60519
TERVYVRELYTVLLG

MCF2

506

P10911
LAIAVDRYVTIFYAL

MC3R

136

P41968
EVLELLLDYAYSSRV

ENC1

96

O14682
LLDYAYSSRVIINEE

ENC1

101

O14682
EQERISYLYNVLLSR

DCST2

536

Q5T1A1
RYSLRLLRAVVYLED

CFAP69

481

A5D8W1
RLRSGLYSAVIVYDE

DUSP4

96

Q13115
LQVYSYRRLGEEALS

SLC22A15

496

Q8IZD6
RDVDVLLLLSNSAYY

INPP5F

636

Q9Y2H2
TRYYLCLQLRDDIVS

EPB41L3

201

Q9Y2J2
VSYVLRNARQLYLSE

IER5L

36

Q5T953
RLAQYTIERYFTLVT

GABRP

206

O00591
YSLALVTVLNEYERA

PKD1

2611

P98161
VETLYRYRSDLEIIF

PPEF1

561

O14829
YYRLVTERTLDRELI

PCDHGA1

401

Q9Y5H4
YLTNRLAEYLVERSG

NAV1

1566

Q8NEY1
ALRYLYGSDQLVVRI

SYT3

306

Q9BQG1
SLRYDYETETLIVRI

SYT6

236

Q5T7P8
AAYLLYAFTRIRSIA

RARS1

531

P54136
NLRHRYYAVDEITIS

USH2A

501

O75445
TEALRLQYRYLDLRS

DARS2

166

Q6PI48
GSRLAEYSVNIRYLL

SERAC1

536

Q96JX3
YAEVLDLRRLYSNDI

POLR1A

1591

O95602
SINSLLERYDTYRDI

SYNE2

1111

Q8WXH0
YIRDYTLLVTSGAAI

TMEM176A

76

Q96HP8
LSGAASRRRYLLYDV

POFUT2

36

Q9Y2G5
LSLARAVYRKAAVYL

ABCC6

761

O95255
AIRLLLEYTDSSYEE

GSTM4

16

Q03013
AIRLLLEYTDSSYEE

GSTM1

16

P09488
GERSSEYLRALFVYE

RNF167

141

Q9H6Y7
RYVARLSAAAVLYLS

SLC39A4

91

Q6P5W5
IYRYSRSLEELLLDA

SCRIB

31

Q14160
ILDDAIVQRLIYYAS

MROH2B

46

Q7Z745
ISLARAVYSDRQLYL

ABCC12

611

Q96J65
DLLLYINARELRITY

OLFM4

311

Q6UX06
LYAISEEVDLYRQLS

FAM83F

291

Q8NEG4
ASTLIRQVLDAVYYL

CAMK1D

121

Q8IU85
VARSAYEIIRDYSLL

URB1

1841

O60287
EYLRERFVAAALSYI

BRINP2

266

Q9C0B6
LEYRNRLEETARALY

ADPRH

331

P54922
LDYSYLIGRLSSDRR

CDYL2

311

Q8N8U2
VDLLAFRRYIACVYL

PGBD2

511

Q6P3X8
VINSYLLAERDLYLE

TGM2

571

P21980
YYQRLEIVEAAIRTL

TMEM45B

41

Q96B21
RTSIIEAQYLRYHDI

PDCD11

436

Q14690
YLYLETSDSLQRFLL

TULP2

306

O00295
YLSKESEVLIYARRD

PIGX

121

Q8TBF5
TYSNTLYLADEIIIR

UMOD

401

P07911
AEQRTESIIHRALYY

SERPINF1

96

P36955
ESIIHRALYYDLISS

SERPINF1

101

P36955
YLLEVYRLAIQSFAS

RLF

96

Q13129
TLLIYNLRARDEGSY

PAPLN

1186

O95428
LHRTIVSERDVYLTY

TRABD

251

Q9H4I3
ATVEELTDTFYYRLR

THEMIS2

526

Q5TEJ8
YNDYLSRLTVVVLRA

SYT15B

341

X6R8R1
LRLRYVGLEDTESYD

SFMBT2

216

Q5VUG0
LERSLEAYRTVEELY

ZNF654

401

Q8IZM8
IEAVGYLYRSVDLRV

TTC41P

1066

Q6P2S7
YLYRSVDLRVIHLGS

TTC41P

1071

Q6P2S7
YAIDSVLEVHIRRYT

VPS13C

376

Q709C8
VLAIRSRYVLEAAVY

TMEM8B

251

A6NDV4
SYDYVRRRLTAEDLF

PLEC

3776

Q15149
RLLAVTDTGALYLYD

WDR6

361

Q9NNW5
GLRLIYYSVAAALTD

TRBV6-7

61

A0A0A0MS04
SRLYIAYQFLLAEDT

SMC2

231

O95347
ILRLSGERVVYSVYS

TAS1R2

376

Q8TE23
AKDLLYRRSRSLVDY

SNX6

306

Q9UNH7
ALVYRLIRDARYAEA

TTC30A

16

Q86WT1
RLSLREKAVAYVNSY

TXNRD3

261

Q86VQ6
VRYRVYELIIEISSV

PSMD5

181

Q16401
DLVYSLSLERISDGY

SEMA3E

76

O15041
AYVRDLRSIVEDYLG

PLEKHG2

116

Q9H7P9
LSLYDGSRLLREDRY

VWA8

536

A3KMH1
SYLERRLFSRLEDIY

WDR91

66

A4D1P6
YIRAAEKLRQEIYSS

TFR2

681

Q9UP52
YELVYTARTEGELLL

TRIM3

386

O75382