Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionRNA polymerase II C-terminal domain phosphoserine binding

SCAF8 SCAF4

1.31e-045732GO:1990269
GeneOntologyBiologicalProcessnegative regulation of termination of RNA polymerase II transcription, poly(A)-coupled

SCAF8 SCAF4

1.20e-052722GO:2000805
GeneOntologyBiologicalProcessnegative regulation of termination of RNA polymerase II transcription

SCAF8 SCAF4

1.20e-052722GO:0120191
GeneOntologyBiologicalProcessnegative regulation of termination of DNA-templated transcription

SCAF8 SCAF4

3.60e-053722GO:0060567
GeneOntologyBiologicalProcesstermination of RNA polymerase II transcription, poly(A)-coupled

SCAF8 SCAF4

3.60e-053722GO:0030846
GeneOntologyBiologicalProcesspositive regulation of cap-independent translational initiation

NCK1 YTHDF2

3.60e-053722GO:1903679
GeneOntologyBiologicalProcessregulation of cap-independent translational initiation

NCK1 YTHDF2

3.60e-053722GO:1903677
GeneOntologyBiologicalProcessregulation of termination of RNA polymerase II transcription, poly(A)-coupled

SCAF8 SCAF4

3.60e-053722GO:2000804
GeneOntologyBiologicalProcessregulation of termination of RNA polymerase II transcription

SCAF8 SCAF4

7.18e-054722GO:1904594
GeneOntologyBiologicalProcessnegative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation

NCK1 DNAJC3

7.18e-054722GO:1903912
GeneOntologyBiologicalProcesspositive regulation of translation in response to endoplasmic reticulum stress

NCK1 DNAJC3

1.19e-045722GO:0036493
GeneOntologyBiologicalProcesspositive regulation of cytoplasmic translational initiation

NCK1 YTHDF2

1.19e-045722GO:1904690
GeneOntologyBiologicalProcesscap-independent translational initiation

NCK1 YTHDF2

1.19e-045722GO:0002190
GeneOntologyBiologicalProcessfemale gamete generation

SRC RXFP2 ASPM MASTL NCAPH YTHDF2

1.29e-04223726GO:0007292
GeneOntologyBiologicalProcesspositive regulation of translational initiation

NCK1 DNAJC3 YTHDF2

1.40e-0429723GO:0045948
GeneOntologyBiologicalProcessregulation of termination of DNA-templated transcription

SCAF8 SCAF4

1.79e-046722GO:0031554
GeneOntologyBiologicalProcessmeiotic cell cycle

SMC3 CALR ASPM MASTL NUF2 NCAPH YTHDF2

2.18e-04350727GO:0051321
GeneOntologyBiologicalProcesseiF2alpha phosphorylation in response to endoplasmic reticulum stress

NCK1 DNAJC3

3.32e-048722GO:0036492
GeneOntologyBiologicalProcessregulation of translation initiation in response to endoplasmic reticulum stress

NCK1 DNAJC3

3.32e-048722GO:0036491
GeneOntologyBiologicalProcesspositive regulation of translation in response to stress

NCK1 DNAJC3

3.32e-048722GO:0032056
GeneOntologyBiologicalProcessregulation of cytoplasmic translational initiation

NCK1 YTHDF2

3.32e-048722GO:1904688
GeneOntologyBiologicalProcesssignal complex assembly

SRC NCK1

3.32e-048722GO:0007172
GeneOntologyBiologicalProcessmeiotic cell cycle process

CALR ASPM MASTL NUF2 NCAPH YTHDF2

3.47e-04268726GO:1903046
GeneOntologyBiologicalProcessnuclear division

SMC3 CALR BUB1 ASPM MASTL NUF2 SKA1 NCAPH

4.06e-04512728GO:0000280
GeneOntologyCellularComponentouter kinetochore

BUB1 NUF2 SKA1

7.84e-0524733GO:0000940
GeneOntologyCellularComponentnuclear matrix

SPTBN4 SMC3 SCAF8 MATR3 CLIC4

1.31e-04140735GO:0016363
GeneOntologyCellularComponentnuclear periphery

SPTBN4 SMC3 SCAF8 MATR3 CLIC4

3.31e-04171735GO:0034399
MousePhenoaxonal spheroids

DOCK3 DST MATR3

3.37e-0517533MP:0010047
MousePhenoaxonal dystrophy

DOCK3 SPTBN4 DST

7.53e-0522533MP:0003225
MousePhenosmall cerebellum

DOCK3 MATR3 PLXNB2 DNAH5 ZIC1

8.51e-05119535MP:0000852
DomainCalreticulin

CALR3 CALR

1.38e-052702IPR009169
DomainCalret/calnex

CALR3 CALR

8.27e-054702IPR001580
DomainCALRETICULIN_1

CALR3 CALR

8.27e-054702PS00803
DomainCALRETICULIN_2

CALR3 CALR

8.27e-054702PS00804
DomainCalret/calnex_CS

CALR3 CALR

8.27e-054702IPR018124
DomainCalreticulin

CALR3 CALR

8.27e-054702PF00262
DomainCalreticulin/calnexin_P_dom

CALR3 CALR

1.37e-045702IPR009033
DomainRNA_pol_II-bd

SCAF8 SCAF4

2.87e-047702IPR006903
DomainCTD_bind

SCAF8 SCAF4

2.87e-047702PF04818
DomainRPR

SCAF8 SCAF4

3.82e-048702SM00582
DomainCID

SCAF8 SCAF4

3.82e-048702PS51391
DomainCID_dom

SCAF8 SCAF4

3.82e-048702IPR006569
DomainCH

SPTBN4 DST ASPM

1.86e-0365703SM00033
DomainCH

SPTBN4 DST ASPM

2.31e-0370703PF00307
Domain-

SPTBN4 DST ASPM

2.40e-03717031.10.418.10
DomainCH

SPTBN4 DST ASPM

2.60e-0373703PS50021
DomainCH-domain

SPTBN4 DST ASPM

2.81e-0375703IPR001715
DomainZnf_C2H2-like

ZNF708 ZBTB49 ZNF630 ZNF680 ZNF273 MATR3 ZSCAN5C ZNF300 ZIC1

2.81e-03796709IPR015880
DomainZnF_C2H2

ZNF708 ZBTB49 ZNF630 ZNF680 ZNF273 MATR3 ZSCAN5C ZNF300 ZIC1

3.10e-03808709SM00355
DomainActinin_actin-bd_CS

SPTBN4 DST

3.33e-0323702IPR001589
DomainSpectrin

SPTBN4 DST

3.33e-0323702PF00435
DomainACTININ_2

SPTBN4 DST

3.33e-0323702PS00020
DomainACTININ_1

SPTBN4 DST

3.33e-0323702PS00019
Pubmed

Tumor suppressor BAP1 nuclear import is governed by transportin-1.

RPL23A CDC37 NAA15 DST SMC3 CALR MATR3 OTUB1 CLIC4 NCAPH PLOD2 YTHDF2 SCAF4 RPL19

1.02e-071149731435446349
Pubmed

Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.

RPL23A CDC37 ACSL3 NAA15 DST SMC3 NSA2 UBTF MATR3 RTCA ASPM CLIC4 NCAPH YTHDF2 RPL19

1.14e-071353731529467282
Pubmed

Large-scale mapping of human protein-protein interactions by mass spectrometry.

RPL23A CDC37 SMC3 CALR MORF4L1 MATR3 RTCA GAS8 ASPM MKLN1 MCC NUF2 SSR3 PLOD2

3.93e-071284731417353931
Pubmed

Systematically defining selective autophagy receptor-specific cargo using autophagosome content profiling.

RPL23A CDC37 ACSL3 DST SMC3 CALR MORF4L1 OTUB1 CARS1 PLXNB2 PLOD2 DNAJC3 YTHDF2 RPL19

4.43e-071297731433545068
Pubmed

A novel role for the peptidyl-prolyl cis-trans isomerase Cyclophilin A in DNA-repair following replication fork stalling via the MRE11-RAD50-NBS1 complex.

RPL23A CDC37 DST NSA2 ASPM CARS1 MASTL CLIC4 SCAF4

6.51e-0747273938943005
Pubmed

A Human Tyrosine Phosphatase Interactome Mapped by Proteomic Profiling.

RPL23A CDC37 ACSL3 NAA15 SMC3 CALR MATR3 OTUB1 MCC NCK1 DNAJC3 RPL19

8.32e-07974731228675297
Pubmed

Two-Dimensional Fractionation Method for Proteome-Wide Cross-Linking Mass Spectrometry Analysis.

RPL23A NAA15 SMC3 MATR3 CARS1 MCC NUF2 NCAPH YTHDF2 SCAF4 RPL19

1.51e-06847731135235311
Pubmed

In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.

RPL23A SPTBN4 ACSL3 DST NSA2 NSD2 MATR3 ASPM ANKRD30B SSR3 NCAPH DNAJC3 PALB2 RPL19

1.56e-061442731435575683
Pubmed

Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.

DOCK3 GABRD SPTBN4 TRIM33 DST MORF4L1 MKLN1 CCDC15 CLIC4 RORB NCK1 COG4 SOS2

2.47e-061285731335914814
Pubmed

Structural Insight into the Mechanism of PALB2 Interaction with MRG15.

MORF4L1 PALB2

4.35e-06273234946951
Pubmed

Identification of a novel calreticulin isoform (Crt2) in human and mouse.

CALR3 CALR

4.35e-06273212384296
Pubmed

SCAF4 and SCAF8, mRNA Anti-Terminator Proteins.

SCAF8 SCAF4

4.35e-06273231104839
Pubmed

Calreticulin-2 is localized in the lumen of the endoplasmic reticulum but is not a Ca2+ -binding protein.

CALR3 CALR

4.35e-06273221590275
Pubmed

miRNA-27b modulates endothelial cell angiogenesis by directly targeting Naa15 in atherogenesis.

NAA15 AOPEP

4.35e-06273227755984
Pubmed

Comparative Interactomes of VRK1 and VRK3 with Their Distinct Roles in the Cell Cycle of Liver Cancer.

RPL23A CDC37 CLUAP1 MATR3 YTHDF2 RPL19

4.78e-0620573628927264
Pubmed

Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.

RPL23A CDC37 ACSL3 SMC3 CALR NSD2 UBTF MATR3 OTUB1 CARS1 NCAPH DNAH5 RPL19

7.58e-061425731330948266
Pubmed

Human transcription factor protein interaction networks.

CDC37 TRIM33 DST SMC3 NSA2 SCAF8 UBTF MORF4L1 MATR3 ELK4 YTHDF2 SCAF4 RPL19

7.81e-061429731335140242
Pubmed

Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.

RPL23A ACSL3 NAA15 DST CALR NSA2 NSD2 UBTF RPL19

9.14e-0665373922586326
Pubmed

Identifying biological pathways that underlie primordial short stature using network analysis.

RPL23A ACSL3 DST SMC3 CALR UBTF MATR3 SRC PLXNB2 SCAF4 RPL19

9.17e-061024731124711643
Pubmed

Nephrin ectodomain engagement results in Src kinase activation, nephrin phosphorylation, Nck recruitment, and actin polymerization.

SRC NCK1

1.30e-05373216543952
Pubmed

MRG15-mediated tethering of PALB2 to unperturbed chromatin protects active genes from genotoxic stress.

MORF4L1 PALB2

1.30e-05373228673974
Pubmed

YTHDF2 protein stabilization by the deubiquitinase OTUB1 promotes prostate cancer cell proliferation via PRSS8 mRNA degradation.

OTUB1 YTHDF2

1.30e-05373238462165
Pubmed

Structural Basis for Multi-specificity of MRG Domains.

MORF4L1 PALB2

1.30e-05373225960410
Pubmed

Functional interaction of human Cdc37 with the androgen receptor but not with the glucocorticoid receptor.

CDC37 SRC

1.30e-05373211085988
Pubmed

Snapshots of the RNA processing factor SCAF8 bound to different phosphorylated forms of the carboxyl-terminal domain of RNA polymerase II.

SCAF8 SCAF4

1.30e-05373218550522
Pubmed

Structural basis for molecular interactions involving MRG domains: implications in chromatin biology.

MORF4L1 PALB2

1.30e-05373222244764
Pubmed

H4K20me0 recognition by BRCA1-BARD1 directs homologous recombination to sister chromatids.

RPL23A ACSL3 DST MLX NSD2 UBTF MORF4L1 MATR3 SSR3 PALB2 SCAF4 RPL19

1.51e-051294731230804502
Pubmed

Characterization of MRFAP1 turnover and interactions downstream of the NEDD8 pathway.

MORF4L1 OTUB1 PALB2

1.52e-052373322038470
Pubmed

KAP1 facilitates reinstatement of heterochromatin after DNA replication.

CDC37 TRIM33 SMC3 RTCA SSR3 NCAPH DNAH5 DNAJC3 YTHDF2

1.66e-0570473929955894
Pubmed

An antibody-based proximity labeling map reveals mechanisms of SARS-CoV-2 inhibition of antiviral immunity.

CDC37 SCAF8 MCC MASTL NCK1 SSR3 COG4 YTHDF2 RPL19

2.28e-0573373934672954
Pubmed

N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.

CDC37 NAA15 DST UBTF MATR3 MASTL NCAPH YTHDF2 SCAF4 RPL19

2.50e-05934731033916271
Pubmed

Genetic and age related models of neurodegeneration in mice: dystrophic axons.

SPTBN4 DST

2.60e-0547321634998
Pubmed

Kinase-dependent adhesion to fibronectin: regulation by calreticulin.

CALR SRC

2.60e-05473218255058
Pubmed

Systematic analysis of human protein complexes identifies chromosome segregation proteins.

NAA15 SMC3 CALR MATR3 BUB1 ASPM MCC MASTL CCDC15 NUF2 PLOD2

2.79e-051155731120360068
Pubmed

CRISPR activation screen identifies BCL-2 proteins and B3GNT2 as drivers of cancer resistance to T cell-mediated cytotoxicity.

RPL23A ACSL3 CALR UBTF DNAJC3 YTHDF2 RPL19

2.84e-0541873735338135
Pubmed

The E3 ubiquitin ligase HECTD1 contributes to cell proliferation through an effect on mitosis.

RPL23A SMC3 NSA2 NSD2 UBTF MATR3 ASPM YTHDF2 RPL19

2.99e-0575973935915203
Pubmed

In silico APC/C substrate discovery reveals cell cycle-dependent degradation of UHRF1 and other chromatin regulators.

RPL23A NSA2 MORF4L1 MATR3 RTCA BUB1 ASPM SSR3 YTHDF2 RPL19

3.47e-05971731033306668
Pubmed

Interlaboratory reproducibility of large-scale human protein-complex analysis by standardized AP-MS.

RPL23A CDC37 DST MCC MASTL RASSF3 RPL19

3.50e-0543273723455922
Pubmed

MYC multimers shield stalled replication forks from RNA polymerase.

RPL23A TRIM33 SMC3 NSA2 UBTF MORF4L1 MATR3 OTUB1 CLIC4 RPL19

4.06e-05989731036424410
Pubmed

Acetylation-Mimic Mutation of TRIM28-Lys304 to Gln Attenuates the Interaction with KRAB-Zinc-Finger Proteins and Affects Gene Expression in Leukemic K562 Cells.

ZNF708 ZNF680 ZNF273 MKLN1 YTHDF2

4.07e-0518173537372979
Pubmed

Fibronectin-stimulated signaling from a focal adhesion kinase-c-Src complex: involvement of the Grb2, p130cas, and Nck adaptor proteins.

SRC NCK1

4.33e-0557329032297
Pubmed

HDLBP-stabilized lncFAL inhibits ferroptosis vulnerability by diminishing Trim69-dependent FSP1 degradation in hepatocellular carcinoma.

PLXNB2 YTHDF2

4.33e-05573236423520
Pubmed

Loss-of-Function GAS8 Mutations Cause Primary Ciliary Dyskinesia and Disrupt the Nexin-Dynein Regulatory Complex.

GAS8 DNAH5

4.33e-05573226387594
Pubmed

Scanning the human proteome for calmodulin-binding proteins.

DOCK3 DST MORF4L1 MATR3

4.34e-059273415840729
Pubmed

Lynch Syndrome

SRC BUB1 MCC

4.63e-053373320301390
Pubmed

Receptor-mediated clustering of FIP200 bypasses the role of LC3 lipidation in autophagy.

RPL23A ACSL3 NAA15 DST UBTF CARS1 RPL19

4.78e-0545473733226137
Pubmed

In vitro nuclear interactome of the HIV-1 Tat protein.

SMC3 NSD2 UBTF MATR3 NCAPH

5.80e-0519573519454010
Pubmed

Targeting USP10 induces degradation of oncogenic ANLN in esophageal squamous cell carcinoma.

RPL23A CDC37 NAA15 DST SMC3 NSA2 UBTF MATR3 NCAPH YTHDF2 RPL19

6.00e-051257731136526897
Pubmed

Protein interactome mining defines melatonin MT1 receptors as integral component of presynaptic protein complexes of neurons.

DST SMC3 CALR OTUB1 MCC COG4

6.08e-0532273626514267
Pubmed

The protein network surrounding the human telomere repeat binding factors TRF1, TRF2, and POT1.

CDC37 DST SMC3 PLOD2 YTHDF2

6.09e-0519773520811636
Pubmed

A High-Density Human Mitochondrial Proximity Interaction Network.

CLPP RPL23A CDC37 ACSL3 NAA15 DST MLX NSA2 MATR3 BUB1 NUF2 PLXNB2

6.20e-051496731232877691
Pubmed

Src-induced phosphorylation of caveolin-2 on tyrosine 19. Phospho-caveolin-2 (Tyr(P)19) is localized near focal adhesions, remains associated with lipid rafts/caveolae, but no longer forms a high molecular mass hetero-oligomer with caveolin-1.

SRC NCK1

6.48e-05673212091389
Pubmed

Elf5-centered transcription factor hub controls trophoblast stem cell self-renewal and differentiation through stoichiometry-sensitive shifts in target gene networks.

RPL23A SMC3 MATR3 RPL19

6.50e-0510273426584622
Pubmed

PINK1 Content in Mitochondria is Regulated by ER-Associated Degradation.

RPL23A ACSL3 DST SMC3 CALR MATR3 RPL19

6.52e-0547773731300519
Pubmed

Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.

RPL23A NAA15 DST SCAF8 BUB1 SSR3 COG4 YTHDF2

6.59e-0565073838777146
Pubmed

Charting the molecular links between driver and susceptibility genes in colorectal cancer.

AOPEP SRC BUB1 MCC

7.83e-0510773424412244
Pubmed

Comprehensive evaluation of coding region point mutations in microsatellite-unstable colorectal cancer.

CDC37 CALR

9.06e-05773230108113
Pubmed

SH3 binding domains in the dopamine D4 receptor.

SRC NCK1

9.06e-0577329843378
Pubmed

Tyrosine phosphorylation of beta-dystroglycan at its WW domain binding motif, PPxY, recruits SH2 domain containing proteins.

SRC NCK1

9.06e-05773211724572
Pubmed

The kinase-deficient Src acts as a suppressor of the Abl kinase for Cbl phosphorylation.

SRC NCK1

9.06e-05773210829062
Pubmed

Male fertility defect associated with disrupted BRCA1-PALB2 interaction in mice.

MORF4L1 PALB2

9.06e-05773225016020
Pubmed

Identification of a ten-amino acid proline-rich SH3 binding site.

SRC NCK1

9.06e-0577328438166
Pubmed

Phosphorylation of Tyr1214 within VEGFR-2 triggers the recruitment of Nck and activation of Fyn leading to SAPK2/p38 activation and endothelial cell migration in response to VEGF.

SRC NCK1

9.06e-05773216966330
Pubmed

PALB2 interacts with KEAP1 to promote NRF2 nuclear accumulation and function.

MORF4L1 PALB2

9.06e-05773222331464
Pubmed

Gab2, a new pleckstrin homology domain-containing adapter protein, acts to uncouple signaling from ERK kinase to Elk-1.

SRC NCK1

9.06e-05773210391903
Pubmed

SERBP1 Promotes Stress Granule Clearance by Regulating 26S Proteasome Activity and G3BP1 Ubiquitination and Protects Male Germ Cells from Thermostimuli Damage.

CDC37 ACSL3 NAA15 CALR OTUB1 CARS1 CLIC4 PLOD2 COG4

9.15e-0587873937223481
Pubmed

TRIM33 drives prostate tumor growth by stabilizing androgen receptor from Skp2-mediated degradation.

TRIM33 SMC3 UBTF MATR3 OTUB1

1.02e-0422073535785414
Pubmed

A directed protein interaction network for investigating intracellular signal transduction.

SPTBN4 CDC37 CALR MATR3 SRC OTUB1 MCC NCK1 PLXNB2 COG4

1.17e-041124731021900206
Pubmed

The Interleukin-2-mTORc1 Kinase Axis Defines the Signaling, Differentiation, and Metabolism of T Helper 1 and Follicular B Helper T Cells.

BUB1 ASPM NUF2 SKA1 NCAPH

1.19e-0422773526410627
Pubmed

The Cdc42-associated kinase ACK1 is not autoinhibited but requires Src for activation.

SRC NCK1

1.21e-04873221309750
Pubmed

Charged linker sequence modulates eukaryotic heat shock protein 90 (Hsp90) chaperone activity.

CDC37 SRC

1.21e-04873222315411
Pubmed

c-Cbl is inducibly tyrosine-phosphorylated by epidermal growth factor stimulation in fibroblasts, and constitutively tyrosine-phosphorylated and associated with v-Src in v-src-transformed fibroblasts.

SRC NCK1

1.21e-0487328635998
Pubmed

Distinct functions of natural ADAM-15 cytoplasmic domain variants in human mammary carcinoma.

SRC NCK1

1.21e-04873218296648
Pubmed

ChAM, a novel motif that mediates PALB2 intrinsic chromatin binding and facilitates DNA repair.

MORF4L1 PALB2

1.21e-04873222193777
Pubmed

The Lyn kinase C-lobe mediates Golgi export of Lyn through conformation-dependent ACSL3 association.

ACSL3 SRC

1.21e-04873220605918
Pubmed

Requirement of heterogeneous nuclear ribonucleoprotein C for BRCA gene expression and homologous recombination.

MORF4L1 PALB2

1.21e-04873223585894
Pubmed

Systems analysis of RhoGEF and RhoGAP regulatory proteins reveals spatially organized RAC1 signalling from integrin adhesions.

CLPP DOCK3 CDC37 SMC3 CALR NCK1 SSR3 PLOD2 SOS2

1.26e-0491673932203420
Pubmed

USP7 targets XIAP for cancer progression: Establishment of a p53-independent therapeutic avenue for glioma.

DST UBTF MATR3 ASPM DNAH5

1.37e-0423473536243803
Pubmed

Prohibitin 1 regulates tumor cell apoptosis via the interaction with X-linked inhibitor of apoptosis protein.

RPL23A SMC3 CALR MATR3 RTCA SSR3 YTHDF2 RPL19

1.40e-0472573827025967
Pubmed

Targeting AMAP1 and cortactin binding bearing an atypical src homology 3/proline interface for prevention of breast cancer invasion and metastasis.

SRC NCK1

1.55e-04973216636290
Pubmed

Artemin activates axonal growth via SFK and ERK-dependent signalling pathways in mature dorsal root ganglia neurons.

SRC NCK1

1.55e-04973217868192
Pubmed

Independent SH2-binding sites mediate interaction of Dok-related protein with RasGTPase-activating protein and Nck.

SRC NCK1

1.55e-04973210428862
Pubmed

HSF2BP Interacts with a Conserved Domain of BRCA2 and Is Required for Mouse Spermatogenesis.

MORF4L1 PALB2

1.55e-04973231242413
Pubmed

An important role for CDK2 in G1 to S checkpoint activation and DNA damage response in human embryonic stem cells.

RPL23A SMC3 CALR MATR3 CLIC4 RPL19

1.90e-0439773621319273
Pubmed

Functional modifications of acid-sensing ion channels by ligand-gated chloride channels.

GABRD ASIC2

1.93e-041073221789198
Pubmed

A protein-interaction network of interferon-stimulated genes extends the innate immune system landscape.

CDC37 ACSL3 DST CALR NSA2 UBTF OTUB1 NCAPH PLOD2 COG4 YTHDF2

1.98e-041440731130833792
Pubmed

Systematic Analysis of Human Protein Phosphatase Interactions and Dynamics.

CDC37 ACSL3 CALR MCC SKA1 PLXNB2 DNAJC3

2.02e-0457373728330616
Pubmed

Irisin Mediates Effects on Bone and Fat via αV Integrin Receptors.

CLPP RPL23A ACSL3 GVINP1 CALR MATR3 SSR3 PLXNB2 PLOD2 DNAJC3 RPL19

2.12e-041451731130550785
Pubmed

Direct interaction between hnRNP-M and CDC5L/PLRG1 proteins affects alternative splice site choice.

SMC3 SCAF8 MORF4L1 BUB1 NUF2 SFI1 NCAPH

2.22e-0458273720467437
Pubmed

Circular RNA circPVT1 promotes nasopharyngeal carcinoma metastasis via the β-TrCP/c-Myc/SRSF1 positive feedback loop.

RPL23A UBTF MATR3 YTHDF2 RPL19

2.23e-0426073536199071
Pubmed

Comprehensive analysis of interactions between the Src-associated protein in mitosis of 68 kDa and the human Src-homology 3 proteome.

DOCK3 SRC NCK1

2.27e-045673322745667
Pubmed

APRIN is a cell cycle specific BRCA2-interacting protein required for genome integrity and a predictor of outcome after chemotherapy in breast cancer.

SMC3 PALB2

2.36e-041173222293751
Pubmed

Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.

CLPP CDC37 ACSL3 NAA15 CALR UBTF OTUB1 ASPM PLXNB2 PLOD2 DNAJC3

2.62e-041487731133957083
Pubmed

Identification of Zika Virus and Dengue Virus Dependency Factors using Functional Genomics.

RPL23A ACSL3 NAA15 SMC3 CALR PLOD2

2.64e-0442273627342126
Pubmed

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.

SPTBN4 ZNF708 AOPEP NSD2 SCAF8 SRC MKLN1 RASSF3 ELK4 DNAJC3 SOS2

2.65e-041489731128611215
Pubmed

Synthetic Lethal and Resistance Interactions with BET Bromodomain Inhibitors in Triple-Negative Breast Cancer.

CDC37 TRIM33 SMC3 NSD2 UBTF MATR3 RTCA OTUB1 NCAPH

2.68e-04101473932416067
Pubmed

FBW7 suppresses ovarian cancer development by targeting the N6-methyladenosine binding protein YTHDF2.

RPL23A UBTF MATR3 OTUB1 SSR3 YTHDF2 RPL19

2.70e-0460173733658012
Pubmed

Proteomic Analysis of the EWS-Fli-1 Interactome Reveals the Role of the Lysosome in EWS-Fli-1 Turnover.

CDC37 TRIM33 MLX CALR UBTF OTUB1

2.74e-0442573624999758
Pubmed

MRG15 is a novel PALB2-interacting factor involved in homologous recombination.

MORF4L1 PALB2

2.83e-041273219553677
Pubmed

The in vivo Interaction Landscape of Histones H3.1 and H3.3.

ZNF680 SMC3 CALR NSD2 UBTF MORF4L1 MASTL

2.90e-0460873736089195
InteractionSEC61B interactions

CLPP RPL23A ACSL3 CLUAP1 CALR3 CALR OTUB1 BUB1 MCC SSR3 PLXNB2 PLOD2 DNAJC3 RPL19

3.59e-077637114int:SEC61B
InteractionPRKCSH interactions

CDC37 TRIM33 CALR3 CALR MATR3 NCAPH DNAJC3 SCAF4

3.34e-06257718int:PRKCSH
InteractionMERTK interactions

CDC37 ACSL3 SMC3 CALR RASSF3 YTHDF2

9.98e-06140716int:MERTK
InteractionTRIM28 interactions

CDC37 TRIM33 ZNF708 ZNF680 SMC3 ZNF273 NSD2 MATR3 SRC RTCA OTUB1 MKLN1 SSR3 NCAPH DNAH5 DNAJC3 YTHDF2

1.04e-0514747117int:TRIM28
InteractionKTN1 interactions

CDC37 TRIM33 DST NUF2 SSR3 NCAPH DNAJC3 RPL19

2.11e-05331718int:KTN1
InteractionPRPSAP2 interactions

CLPP NSD2 NCK1 ELK4 RPL19

3.01e-05102715int:PRPSAP2
InteractionZNF189 interactions

RPL23A SRC BUB1 MCC

3.12e-0551714int:ZNF189
InteractionZNF543 interactions

ZNF708 UBTF MCC

5.32e-0521713int:ZNF543
InteractionMSANTD3 interactions

SMC3 BUB1 MCC

5.32e-0521713int:MSANTD3
InteractionMST1R interactions

CDC37 SMC3 SRC CCDC168 NCAPH RPL19

7.42e-05200716int:MST1R
InteractionHSPA4 interactions

CLPP CDC37 TRIM33 MORF4L1 SRC OTUB1 ASPM CARS1 NUF2 DNAJC3

1.10e-046677110int:HSPA4
InteractionNCAPH interactions

RPL23A CALR MATR3 ASPM NCAPH YTHDF2 RPL19

1.20e-04315717int:NCAPH
InteractionUSP15 interactions

RPL23A CDC37 SMC3 MATR3 OTUB1 MKLN1 NCAPH PLOD2 RPL19

1.23e-04546719int:USP15
InteractionBAAT interactions

SRC BUB1 MCC

1.29e-0428713int:BAAT
InteractionSPC24 interactions

BUB1 ASPM NUF2 SKA1

1.66e-0478714int:SPC24
InteractionBAP1 interactions

RPL23A CDC37 NAA15 DST SMC3 CALR MATR3 OTUB1 CLIC4 NCAPH PLOD2 YTHDF2 SCAF4 RPL19

1.69e-0413147114int:BAP1
InteractionELF5 interactions

RPL23A TRIM33 SMC3 MATR3 RPL19

1.71e-04147715int:ELF5
InteractionRPL38 interactions

RPL23A DST GVINP1 NSD2 SSR3 NCAPH RPL19

1.73e-04334717int:RPL38
InteractionCCDC180 interactions

SRC BUB1 MCC

1.75e-0431713int:CCDC180
InteractionCALU interactions

TRIM33 CLUAP1 CALR3 CALR ASPM PLOD2 DNAJC3

1.79e-04336717int:CALU
InteractionTXLNA interactions

CDC37 DST OTUB1 GAS8 MCC PLOD2

1.84e-04236716int:TXLNA
InteractionMAD1L1 interactions

CDC37 KIF9 MLX UBTF GAS8

1.87e-04150715int:MAD1L1
InteractionCDC5L interactions

RPL23A DST SMC3 SCAF8 UBTF MORF4L1 MATR3 BUB1 NUF2 SFI1 NCAPH

1.87e-048557111int:CDC5L
InteractionCTNNB1 interactions

RPL23A CDC37 TRIM33 NAA15 DST NSD2 MATR3 SRC OTUB1 ASPM NCAPH YTHDF2

1.93e-0410097112int:CTNNB1
InteractionRNF2 interactions

RPL23A SMC3 CALR NSA2 UBTF MORF4L1 MATR3 OTUB1 NCAPH YTHDF2 RPL19

2.09e-048667111int:RNF2
InteractionTRMO interactions

SRC BUB1 MCC

2.12e-0433713int:TRMO
InteractionMAGEB2 interactions

RPL23A CALR NSA2 NSD2 UBTF SCAF4 RPL19

2.26e-04349717int:MAGEB2
InteractionRCN1 interactions

TRIM33 CALR3 CALR MATR3 ASPM DNAJC3

2.51e-04250716int:RCN1
InteractionZWINT interactions

CDC37 BUB1 MASTL NUF2 SSR3

2.53e-04160715int:ZWINT
InteractionPPIA interactions

RPL23A CDC37 DST NSA2 NSD2 ASPM CARS1 MASTL CLIC4 YTHDF2 SCAF4

2.60e-048887111int:PPIA
InteractionSIRT7 interactions

RPL23A ACSL3 NAA15 DST CALR NSA2 NSD2 UBTF ELK4 RPL19

2.67e-047447110int:SIRT7
InteractionALDOB interactions

SRC BUB1 MCC

2.75e-0436713int:ALDOB
InteractionASPM interactions

CLUAP1 CALR ASPM SSR3 NCAPH

2.83e-04164715int:ASPM
InteractionSSB interactions

RPL23A CDC37 TRIM33 DST SMC3 CALR OTUB1 RPL19

2.95e-04484718int:SSB
InteractionHIPK4 interactions

CDC37 ACSL3 YTHDF2

2.99e-0437713int:HIPK4
InteractionMRFAP1 interactions

CLUAP1 MORF4L1 OTUB1 PALB2

3.00e-0491714int:MRFAP1
InteractionDNAJC10 interactions

CLPP TRIM33 CALR3 CALR DNAJC3 SCAF4

3.09e-04260716int:DNAJC10
InteractionGANAB interactions

TRIM33 CALR3 CALR MATR3 NCAPH PLOD2 DNAJC3

3.12e-04368717int:GANAB
InteractionRPL10A interactions

RPL23A DST NSA2 MATR3 NCK1 SSR3 NCAPH RPL19

3.20e-04490718int:RPL10A
InteractionZBTB26 interactions

CDC37 MORF4L1 GAS8

3.24e-0438713int:ZBTB26
InteractionBEND7 interactions

CDC37 MLX PLEKHF2 MORF4L1

3.40e-0494714int:BEND7
InteractionCALM1 interactions

DOCK3 TRIM33 DST CALR MORF4L1 MATR3 SRC ASPM SFI1

3.40e-04626719int:CALM1
InteractionDCTN1 interactions

CDC37 NAA15 DST MATR3 NUF2 SKA1 NCAPH YTHDF2

3.52e-04497718int:DCTN1
InteractionCEP78 interactions

TRIM33 CALR ASPM MCC

3.68e-0496714int:CEP78
InteractionBRCA1 interactions

RPL23A CDC37 TRIM33 NAA15 DST SMC3 NSD2 UBTF MORF4L1 MATR3 CARS1 ELK4 PALB2

3.74e-0412497113int:BRCA1
InteractionALK interactions

CDC37 ACSL3 SRC NCK1 SSR3 DNAJC3

3.85e-04271716int:ALK
InteractionFLT4 interactions

CDC37 ACSL3 SMC3 CALR NCK1 NCAPH

3.93e-04272716int:FLT4
InteractionKARS1 interactions

PLEKHF2 SRC OTUB1 CARS1 NCAPH PLOD2 RPL19

3.96e-04383717int:KARS1
InteractionCDK2 interactions

RPL23A CDC37 DST SMC3 CALR UBTF MATR3 BUB1 CLIC4 RPL19

4.00e-047837110int:CDK2
InteractionNCAPG2 interactions

CLPP CLUAP1 ASPM NCAPH

4.30e-04100714int:NCAPG2
InteractionRPS20 interactions

RPL23A NAA15 OTUB1 SSR3 NCAPH COG4 YTHDF2 RPL19

4.35e-04513718int:RPS20
InteractionCEBPB interactions

RPL23A CDC37 NAA15 SMC3 CALR NSA2 UBTF MATR3 OTUB1 ASPM NCAPH YTHDF2 SCAF4 RPL19

4.41e-0414437114int:CEBPB
GeneFamilyZinc fingers C2H2-type|ZF class homeoboxes and pseudogenes

ZNF708 ZBTB49 ZNF630 ZNF680 ZNF273 ZSCAN5C ZNF300 ZIC1

7.29e-0471850828
CoexpressionWINNEPENNINCKX_MELANOMA_METASTASIS_UP

NSD2 BUB1 ASPM NUF2 SSR3 NCAPH PLOD2

3.50e-07162737M6387
CoexpressionFISCHER_DREAM_TARGETS

ZNF680 NAA15 SMC3 ZNF273 NSD2 BUB1 ASPM MASTL CCDC15 CLIC4 NUF2 SKA1 NCAPH PALB2

3.93e-079697314M149
CoexpressionGSE13547_2H_VS_12_H_ANTI_IGM_STIM_BCELL_UP

DST BUB1 ASPM NUF2 NCAPH PLXNB2 PLOD2

6.13e-07176737M2981
CoexpressionJOHNSTONE_PARVB_TARGETS_3_DN

NAA15 SMC3 ZNF273 BUB1 ASPM MASTL NCK1 NUF2 ELK4 SSR3 NCAPH DNAJC3 YTHDF2

8.13e-078777313M2241
CoexpressionZHONG_PFC_C3_UNKNOWN_INP

BUB1 NUF2 SKA1 NCAPH

3.80e-0638734M39083
CoexpressionMITSIADES_RESPONSE_TO_APLIDIN_DN

NAA15 SMC3 NSD2 BUB1 ASPM NCAPH PALB2

6.29e-06250737M11318
CoexpressionGSE13547_CTRL_VS_ANTI_IGM_STIM_BCELL_2H_UP

NSD2 BUB1 ASPM CLIC4 NUF2 PLOD2

1.23e-05183736M2993
CoexpressionFLORIO_NEOCORTEX_BASAL_RADIAL_GLIA_DN

BUB1 ASPM MCC NUF2 SKA1 NCAPH

1.52e-05190736M761
CoexpressionGSE360_L_MAJOR_VS_B_MALAYI_HIGH_DOSE_DC_DN

ZNF273 SCAF8 RTCA BUB1 MCC PLXNB2

1.87e-05197736M5210
CoexpressionWHITEFORD_PEDIATRIC_CANCER_MARKERS

NSD2 BUB1 ZNF300 NUF2 NCAPH

1.92e-05117735M7854
CoexpressionGSE21063_WT_VS_NFATC1_KO_8H_ANTI_IGM_STIM_BCELL_UP

RTCA BUB1 ASPM NUF2 SKA1 NCAPH

1.98e-05199736M8277
CoexpressionGSE8921_UNSTIM_VS_TLR1_2_STIM_MONOCYTE_6H_DN

NSD2 RTCA BUB1 MASTL NUF2 SKA1

2.04e-05200736M6417
CoexpressionGSE15750_DAY6_VS_DAY10_TRAF6KO_EFF_CD8_TCELL_UP

BUB1 ASPM RASSF3 NUF2 SKA1 NCAPH

2.04e-05200736M3580
CoexpressionGSE15750_DAY6_VS_DAY10_EFF_CD8_TCELL_UP

NSD2 BUB1 ASPM NUF2 SKA1 NCAPH

2.04e-05200736M3577
CoexpressionMARSON_BOUND_BY_E2F4_UNSTIMULATED

SMC3 MATR3 BUB1 ASPM MASTL RASSF3 NUF2 SKA1 NCAPH PALB2

2.79e-057147310M1744
CoexpressionRODRIGUES_THYROID_CARCINOMA_ANAPLASTIC_UP

NAA15 SMC3 MATR3 RTCA ASPM CARS1 CLIC4 NUF2 SSR3 ZIC1

3.03e-057217310M10237
CoexpressionMANNO_MIDBRAIN_NEUROTYPES_HPROGFPL

RPL23A BUB1 ASPM MASTL NUF2 NCAPH PLOD2

3.22e-05322737M39060
CoexpressionKINSEY_TARGETS_OF_EWSR1_FLII_FUSION_UP

ZNF680 MLX SMC3 NSD2 PLEKHF2 MATR3 RTCA BUB1 ASPM MASTL NUF2 SKA1 NCAPH

5.13e-0512907313M80
CoexpressionRODRIGUES_THYROID_CARCINOMA_POORLY_DIFFERENTIATED_UP

NAA15 SMC3 MATR3 RTCA CARS1 MKLN1 MASTL CLIC4 SSR3

7.38e-05644739M10501
CoexpressionBENPORATH_NANOG_TARGETS

KIF9 CALR MORF4L1 OTUB1 MCC ZNF300 CLIC4 SFI1 PALB2 ZIC1 SCAF4

8.66e-059887311M6616
CoexpressionSEIDEN_ONCOGENESIS_BY_MET

NSA2 RTCA CLIC4 PLOD2

1.13e-0489734M3231
CoexpressionGAVIN_FOXP3_TARGETS_CLUSTER_P6

ST8SIA6 BUB1 ASPM NUF2

1.34e-0493734M1735
CoexpressionDE_YY1_TARGETS_DN

NAA15 DST CLIC4 RASSF3

1.34e-0493734M3278
CoexpressionGAVIN_FOXP3_TARGETS_CLUSTER_P6

ST8SIA6 BUB1 ASPM NUF2

1.46e-0495734MM1217
CoexpressionGEORGES_TARGETS_OF_MIR192_AND_MIR215

DST ZNF273 NSD2 PLEKHF2 ASPM CCDC15 NUF2 SKA1 NCAPH DNAJC3

1.77e-048927310M18120
CoexpressionGSE13547_CTRL_VS_ANTI_IGM_STIM_BCELL_12H_UP

BUB1 ASPM NUF2 SKA1 NCAPH

1.78e-04187735M2984
CoexpressionPUJANA_BRCA2_PCC_NETWORK

SMC3 ZNF273 NSD2 RTCA BUB1 NCK1 NCAPH

1.85e-04426737M9516
CoexpressionFUJII_YBX1_TARGETS_DN

NSD2 ASPM MASTL NCAPH DNAJC3

2.11e-04194735M14340
CoexpressionYU_MYC_TARGETS_UP

BUB1 ASPM CLIC4

2.20e-0442733MM1150
CoexpressionGSE5542_UNTREATED_VS_IFNA_TREATED_EPITHELIAL_CELLS_24H_DN

RPL23A UBTF ZNF300 RASSF3 ELK4

2.26e-04197735M6525
CoexpressionYU_MYC_TARGETS_UP

BUB1 ASPM CLIC4

2.36e-0443733M1249
CoexpressionGSE2405_HEAT_KILLED_LYSATE_VS_LIVE_A_PHAGOCYTOPHILUM_STIM_NEUTROPHIL_9H_UP

NSD2 ASPM CLIC4 NUF2 SKA1

2.37e-04199735M6198
CoexpressionGSE41867_LCMV_ARMSTRONG_VS_CLONE13_DAY8_EFFECTOR_CD8_TCELL_UP

NSA2 RASSF3 SFI1 PLXNB2 DNAJC3

2.43e-04200735M9478
CoexpressionGSE30962_PRIMARY_VS_SECONDARY_ACUTE_LCMV_INF_CD8_TCELL_UP

BUB1 ASPM NUF2 SKA1 NCAPH

2.43e-04200735M5041
CoexpressionGSE11961_FOLLICULAR_BCELL_VS_MARGINAL_ZONE_BCELL_UP

GABRD CLIC4 NCK1 DNAH5 SOS2

2.43e-04200735M9381
CoexpressionGSE29618_PRE_VS_DAY7_POST_TIV_FLU_VACCINE_PDC_DN

CLUAP1 NSD2 RTCA NCK1 RPL19

2.43e-04200735M5005
CoexpressionGSE43955_TH0_VS_TGFB_IL6_IL23_TH17_ACT_CD4_TCELL_52H_DN

MKLN1 CLIC4 NCK1 SSR3 PLXNB2

2.43e-04200735M9653
CoexpressionGSE3982_MAC_VS_BASOPHIL_UP

DOCK3 ACSL3 RTCA MKLN1 SSR3

2.43e-04200735M5496
CoexpressionGSE17721_CTRL_VS_LPS_6H_BMDC_UP

SMC3 MATR3 RASSF3 PLXNB2 RPL19

2.43e-04200735M3691
CoexpressionGSE39110_DAY3_VS_DAY6_POST_IMMUNIZATION_CD8_TCELL_DN

BUB1 ASPM NUF2 SKA1 PLOD2

2.43e-04200735M9277
CoexpressionLEE_EARLY_T_LYMPHOCYTE_UP

NSD2 BUB1 ASPM NUF2

2.65e-04111734M7357
CoexpressionFAELT_B_CLL_WITH_VH3_21_UP

CALR UBTF SRC

2.70e-0445733M15164
CoexpressionSHEDDEN_LUNG_CANCER_POOR_SURVIVAL_A6

NSD2 RTCA BUB1 ASPM SKA1 NCAPH PLOD2

2.87e-04458737M8520
CoexpressionZHAN_MULTIPLE_MYELOMA_PR_UP

ASPM NUF2 SKA1

2.89e-0446733M4888
CoexpressionHE_LIM_SUN_FETAL_LUNG_C5_PRO_B_CELL

NSD2 BUB1 ASPM MASTL NUF2 SKA1 NCAPH

3.71e-04478737M45785
CoexpressionBHATI_G2M_ARREST_BY_2METHOXYESTRADIOL_UP

CALR BUB1 ASPM NUF2

3.79e-04122734M18550
CoexpressionBIDUS_METASTASIS_UP

NSD2 BUB1 CCDC15 NCAPH PLOD2

3.84e-04221735M15866
CoexpressionHE_LIM_SUN_FETAL_LUNG_C6_DEUTEROSOMAL_CELL

BUB1 ASPM CCDC15 NUF2 NCAPH

3.84e-04221735M45789
CoexpressionVAN_DEN_BIGGELAAR_PBMC_PREVNAR_9MO_INFANT_STIMULATED_VS_UNSTIMULATED_9MO_UP

BUB1 ASPM SKA1 NCAPH

4.42e-04127734M40952
CoexpressionKANG_DOXORUBICIN_RESISTANCE_UP

NSD2 BUB1 ASPM

4.64e-0454733M1037
CoexpressionFAN_EMBRYONIC_CTX_NSC_2

BUB1 ASPM NUF2 SKA1 NCAPH

4.89e-04233735M39036
CoexpressionZHONG_PFC_C1_OPC

BUB1 ASPM NUF2 SKA1 NCAPH

5.38e-04238735M39096
CoexpressionDELACROIX_RARG_BOUND_MEF

CLPP DST CALR SRC GAS8 RPL19

5.51e-04366736M2461
ToppCellPCW_13-14-Mesenchymal-Mesenchymal_cycling|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

NSD2 BUB1 ASPM MASTL CCDC15 NUF2 SKA1 NCAPH

1.19e-091967381d2e0b328eb822db7521b5f5724d4bd17c0bad5f
ToppCellPND03-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-VEC-VEC_G2M|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

BUB1 ASPM MASTL CCDC168 NUF2 SKA1 NCAPH

1.57e-08175737d43ae33a6256606ce848247cad32d74f21b38988
ToppCell10x5'-Liver-Lymphocytic_B_plasma-Plasmablasts|Liver / Manually curated celltypes from each tissue

BUB1 ASPM CLIC4 NUF2 SSR3 SKA1 NCAPH

1.69e-081777371d88ae316d65ca5fdc736c9da93885b6b40c32bb
ToppCellPND14-Endothelial-Endothelial_blood-vessel-Microvascular_EC-EPC|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

NSD2 BUB1 ASPM MASTL NUF2 SKA1 NCAPH

1.83e-0817973754191c00b29f53b520cd3243b5791daa4a2c72d7
ToppCellfacs-Skin-Skin_Anagen-18m-Epithelial-actively_dividing_stem_cell|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BUB1 ASPM MASTL RASSF3 NUF2 SKA1 NCAPH

2.05e-08182737bc6a120dedc813c58baac1428c39851a07b71ba7
ToppCellfacs-Skin-Skin_Anagen-18m-Epithelial-keratinocyte_stem_cell|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BUB1 ASPM MASTL RASSF3 NUF2 SKA1 NCAPH

2.05e-081827370fc45214f0b0766f69be6eff69cc4bec574023aa
ToppCellControl-Endothelial-Endothelial-FOXM1|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

NSD2 BUB1 ASPM MASTL CCDC15 NUF2 NCAPH

2.66e-081897371e1499b062d9c647c8f38b0c4e0d871d159be5dd
ToppCelldroplet-Spleen-nan-18m-Lymphocytic-immature_NKT_cell|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NSD2 BUB1 ASPM MASTL NUF2 SKA1 NCAPH

2.76e-08190737b99271d139c8d01e20feb95d99f79c9b2756b4cb
ToppCellMild-T/NK_proliferative|World / Disease group and Cell class

NSD2 BUB1 ASPM MASTL NUF2 SKA1 NCAPH

2.86e-081917379dba5526fd5ea8065ad305feb2ee562335f887c6
ToppCell3'-Broncho-tracheal-Immune_Lymphocytic-Lymphocytic_B-plasma_cell-Plasma_cells-Plasma_cells_L.1.7.1.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CALR BUB1 ASPM NUF2 SSR3 SKA1 NCAPH

2.97e-08192737b9c606547c303a099a653169923a44c20816a604
ToppCellPSB-critical-LOC-Epithelial-FOXN4+|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

NSD2 BUB1 ASPM CCDC15 NUF2 SKA1 NCAPH

3.07e-08193737b7d9c5bed524423e92f01496a9f8fad11b33a3f7
ToppCelldroplet-Lung-1m-Hematologic-myeloid-alveolar_macrophage-proliferating_alveolar_macrophage|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

NSD2 BUB1 ASPM MASTL NUF2 SKA1 NCAPH

3.30e-08195737c1435e61e4f0cf457f26ae436936048932ceb0db
ToppCelldroplet-Thymus-nan-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SMC3 NSD2 BUB1 ASPM NUF2 SKA1 NCAPH

3.30e-08195737043e2f19d95e94cd5219e2c415f322ed340aa80f
ToppCellPND10-Endothelial-Endothelial_blood-vessel-Microvascular_EC-EPC-EPC_G2M|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

NSD2 BUB1 ASPM MASTL NUF2 SKA1 NCAPH

3.42e-0819673720383d576708b7e4bfce3e9fe40548cce496e3cb
ToppCellPND10-Endothelial-Endothelial_blood-vessel-Microvascular_EC-EPC|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

NSD2 BUB1 ASPM MASTL NUF2 SKA1 NCAPH

3.42e-081967370644bd14a944b9c9759a295dfdd5e67a4775f20a
ToppCellPCW_10-12-Mesenchymal-Mesenchymal_cycling-mes_proliferating3_(7)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

BUB1 ASPM MASTL CCDC15 NUF2 SKA1 NCAPH

3.54e-0819773784ed777cdba569200a3ef1654d8a12f17fcfb7f1
ToppCellPCW_10-12-Mesenchymal-Mesenchymal_cycling|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

BUB1 ASPM MASTL CCDC15 NUF2 SKA1 NCAPH

3.54e-081977378b616cde333bdbc0c591035ad9e4949155866245
ToppCell367C-Myeloid-Dendritic-cDC_proliferating_1|Dendritic / Donor, Lineage, Cell class and subclass (all cells)

MATR3 BUB1 ASPM MASTL NUF2 SKA1 NCAPH

3.79e-081997373d876f172487425b37b2f658dae59e0f293ee76e
ToppCelltumor_Lung-T/NK_cells-Undetermined|tumor_Lung / Location, Cell class and cell subclass

SMC3 NSD2 BUB1 ASPM NUF2 SKA1 NCAPH

3.79e-081997372e222e2e080bc2be63d0fdf285e1790676b911ef
ToppCellLPS_anti-TNF-Endothelial-Endothelial-FOXM1|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

NSD2 BUB1 ASPM CCDC15 NUF2 SKA1 NCAPH

3.79e-0819973798575fcce726589e93fbb4df1aab03e57cb56076
ToppCell3'_v3-lymph-node_spleen-Lymphocytic_B_plasma-Plasmablasts|lymph-node_spleen / Manually curated celltypes from each tissue

CALR BUB1 ASPM NUF2 SSR3 SKA1 NCAPH

3.92e-08200737b0d708715f09ec1f67fdef3b100a91c8ff2747a7
ToppCellSevere-T/NK_proliferative|Severe / Disease group and Cell class

SMC3 NSD2 BUB1 ASPM NUF2 SKA1 NCAPH

3.92e-082007374723613a9f56bff422fc98722128d57b6adf3c5d
ToppCellCOVID_non-vent-Lymphocytic-Proliferative_Lymphocyte-|COVID_non-vent / Disease condition, Lineage, Cell class and subclass

SMC3 NSD2 BUB1 ASPM NUF2 SKA1 NCAPH

3.92e-0820073704bf9e6a0fbd792b49eed63dabba5d6fafed8c07
ToppCellCOVID_vent-Lymphocytic-Proliferative_Lymphocyte-|COVID_vent / Disease condition, Lineage, Cell class and subclass

SMC3 NSD2 BUB1 ASPM NUF2 SKA1 NCAPH

3.92e-082007377e4c0db43a03ca11380a54f44a3cf1991e055b80
ToppCellCOVID_non-vent-Lymphocytic-Proliferative_Lymphocyte|COVID_non-vent / Disease condition, Lineage, Cell class and subclass

SMC3 NSD2 BUB1 ASPM NUF2 SKA1 NCAPH

3.92e-08200737f6b5320cdfe640a71e6e2df26f30d42e64b1c921
ToppCellCOVID_vent-Lymphocytic-Proliferative_Lymphocyte|COVID_vent / Disease condition, Lineage, Cell class and subclass

SMC3 NSD2 BUB1 ASPM NUF2 SKA1 NCAPH

3.92e-082007379775ca7dedb76fcbb74f80f86b33c94e394c320a
ToppCellLPS-antiTNF-Epithelial_airway-Mes-Epi-like|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

GABRD BUB1 ASPM NUF2 SKA1 DNAH5

2.98e-071647364307b002fb41ddfc7ab8a6bca66a60942c250052
ToppCellLPS-antiTNF-Epithelial_airway-Mes-Epi-like-Airway|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

GABRD BUB1 ASPM NUF2 SKA1 DNAH5

2.98e-071647361d84aa5b925f502ee9c5fa39714490f613a58028
ToppCellDividing_Macrophages-Cryobiopsy_01|World / lung cells shred on cell class, cell subclass, sample id

ZNF680 BUB1 ASPM NUF2 SKA1 NCAPH

3.20e-07166736c503036f3c19ef186e1e62c9643c49dea3827f51
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Cycling_Endothelial_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

BUB1 ASPM CCDC15 NUF2 SKA1 NCAPH

3.31e-07167736bc132b51dec4e8f1cd2b2cd89f83641976e09292
ToppCellPND14-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_T-Treg-Treg_G2M|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

BUB1 ASPM MASTL NUF2 SKA1 PALB2

3.31e-07167736d21635df8b74189e3309eaf435af381fbe412574
ToppCellPND14-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK-ILC-ILC_G2M|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

STAB2 BUB1 ASPM NUF2 SKA1 PALB2

3.68e-07170736b04e2f84024baaae9b4ff19bdac8c69afdb92a76
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Cycling_Myofibroblast-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

GABRD RXFP2 BUB1 ASPM CCDC15 NCAPH

3.81e-07171736b0373ed8283ee1792b6a490bff93906546978593
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Cycling_Myofibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

GABRD RXFP2 BUB1 ASPM CCDC15 NCAPH

3.81e-07171736b92963f9f247d2e5e2e6c51c6dbf70e527cd2f55
ToppCellDividing_Macrophages-IPF_03|World / lung cells shred on cell class, cell subclass, sample id

BUB1 ASPM CCDC168 NUF2 SKA1 NCAPH

4.36e-071757360a8bf455babb3271aa00642199fb58b0b02dc3ac
ToppCelldroplet-Spleen-nan-21m-Lymphocytic-immature_NKT_cell|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BUB1 ASPM MASTL NUF2 SKA1 NCAPH

4.98e-07179736dabecd283c1f0f71a66b804c99be8bd48ea36e35
ToppCellControl-Developping_Plasmablast|Control / disease group and sub_cluster of B and Plasma cells(res = 0.5)

NSD2 BUB1 ASPM NUF2 SKA1 NCAPH

4.98e-071797369383568f78b07b8cca72ece5d15fea209aa54ea9
ToppCellPND14-Endothelial-Endothelial_blood-vessel-Microvascular_EC-EPC-EPC_G2M|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

NSD2 BUB1 ASPM NUF2 SKA1 NCAPH

5.14e-071807365e1680088065be14447d5d5465f91f7edd071a1e
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell_cycling|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

NSD2 BUB1 ASPM NUF2 SKA1 NCAPH

5.14e-07180736401df9cddcbca1eb8f0d2687bcacd98e95dc1493
ToppCelldroplet-Lung-3m-Hematologic-lymphocytic-Proliferating_T_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

BUB1 ASPM MASTL NUF2 SKA1 NCAPH

5.31e-07181736cf13bf7a531a2d40f8d778629cf2431b684f65f3
ToppCelldroplet-Lung-3m-Hematologic-lymphocytic-Proliferating_T_cell-proliferating_T|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

BUB1 ASPM MASTL NUF2 SKA1 NCAPH

5.31e-0718173674311aac2fe27dc02a9be3bc20e0c7ef1c239049
ToppCell10x5'-bone_marrow-Lymphocytic_T_CD4/8-lo-Cycling_T|bone_marrow / Manually curated celltypes from each tissue

SMC3 BUB1 ASPM NUF2 SKA1 NCAPH

5.66e-07183736a48a6313f2f144586951cece97ec31f6d72361df
ToppCellTCGA-Liver-Primary_Tumor-Hepatocellular_Carcinoma-Hepatocellular_Carcinoma-5|TCGA-Liver / Sample_Type by Project: Shred V9

BUB1 ASPM MASTL NUF2 SKA1 NCAPH

5.66e-07183736f604a8b62c7088fad8365dbf8d910fc980bd3ba8
ToppCellControl-immature_Neutrophil-|Control / Disease condition and Cell class

ZNF273 NSD2 MATR3 BUB1 ASPM NCAPH

5.85e-07184736c4e8ba82a6aa76c46f05a71d5f1c7926555318cf
ToppCellControl-immature_Neutrophil|Control / Disease condition and Cell class

ZNF273 NSD2 MATR3 BUB1 ASPM NCAPH

5.85e-071847362fdae5c6b3eb2232881d933a8c1061fda3623016
ToppCelldroplet-Lung-1m-Hematologic-lymphocytic-Proliferating_T_cell|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

BUB1 ASPM MASTL NUF2 SKA1 NCAPH

6.03e-071857360e0f043ad6d2a62cd47ce39911ad81feab4a4d7e
ToppCelldroplet-Lung-1m-Hematologic-lymphocytic-Proliferating_T_cell-proliferating_T|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

BUB1 ASPM MASTL NUF2 SKA1 NCAPH

6.03e-0718573689b85ce8026dc80c1bd9f76dfe16401c173b7946
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_G2M|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

NSD2 BUB1 ASPM NUF2 SKA1 NCAPH

6.03e-0718573630e041d6f6e310d64809e9d6d93cd30052972f3b
ToppCellfacs-Skin-Telogen-3m-Epithelial-actively_dividing_stem_cell|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BUB1 ASPM MASTL NUF2 SKA1 NCAPH

6.23e-071867369feef5936985e936b3d88f9d1bb012abb6468570
ToppCellfacs-Skin-Telogen-3m-Epithelial-keratinocyte_stem_cell|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BUB1 ASPM MASTL NUF2 SKA1 NCAPH

6.23e-0718673689f5b06bc56674af304912d481ac697c7c870904
ToppCellCOVID-19_Mild-Neu_4|COVID-19_Mild / 5 Neutrophil clusters in COVID-19 patients

RPL23A SMC3 NSD2 ASPM MASTL RPL19

6.43e-07187736714851e757c71c559ee6413a3f61d6c117c79ad2
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

NSD2 BUB1 ASPM NUF2 SKA1 NCAPH

6.43e-071877369351fa87b69a951af85b10bf91fe9b1cce8c0517
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell_cycling|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

NSD2 BUB1 ASPM NUF2 SKA1 NCAPH

6.43e-07187736057569c9437219ecc396aa6e673b1178a2273837
ToppCell3'-Broncho-tracheal-Immune_Lymphocytic-Lymphocytic_T/NK-natural_killer_cell-NK_cells-NK_cells_L.1.3.2.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

BUB1 ASPM CCDC15 CCDC168 NUF2 NCAPH

6.63e-07188736319fbeca200ab998daf49fcaee0bfdb57bf7ee4b
ToppCellPND10-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-SCMF-SCMF_G2M|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

BUB1 ASPM MASTL NUF2 SKA1 NCAPH

6.63e-0718873695d0a796d62ce6d121e2028c378faffc14b35275
ToppCell3'_v3-bone_marrow-Lymphocytic_B_plasma-Plasmablasts|bone_marrow / Manually curated celltypes from each tissue

CALR BUB1 CLIC4 NUF2 SSR3 SKA1

6.63e-071887364caae2acd9ec0eb79b7476a1e59f30f39afddcda
ToppCellfacs-Skin-Anagen-3m-Epithelial-actively_dividing_stem_cell|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BUB1 ASPM MASTL NUF2 SKA1 NCAPH

6.84e-07189736bfa3ed1360991a3e32fad133017c413f8adc1eba
ToppCellfacs-Skin-Anagen-3m-Epithelial-keratinocyte_stem_cell|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BUB1 ASPM MASTL NUF2 SKA1 NCAPH

6.84e-0718973696f10c63656e446b4bb712f012e91ae986f8c2d0
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Cycling_Endothelial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

BUB1 ASPM CCDC15 NUF2 SKA1 NCAPH

7.05e-0719073631de1727822e9818652946dfb962daee77ffad68
ToppCelldroplet-Lung-21m-Hematologic-lymphocytic-Proliferating_T_cell-proliferating_T|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

BUB1 ASPM MASTL NUF2 SKA1 NCAPH

7.27e-0719173615dbc5a03bfab8931c0fd385b0f25874736ae874
ToppCelldroplet-Lung-LUNG-30m-Lymphocytic-Proliferating_T|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NSD2 BUB1 ASPM NUF2 SKA1 NCAPH

7.27e-07191736239300ff76f2c855b2b04d3002461158be90a01b
ToppCellEndothelial-D_(cycle)|World / shred on cell class and cell subclass (v4)

NSD2 BUB1 ASPM NUF2 SKA1 NCAPH

7.27e-0719173649a4d8f181558e3be9527a8ff9a178f3bb01323c
ToppCellDividing_Macrophages-HP_01|World / lung cells shred on cell class, cell subclass, sample id

BUB1 ASPM CCDC15 NUF2 SKA1 NCAPH

7.27e-071917363e567ed6b5fefafa7f460e49d25d60bb52a0a6c8
ToppCell3'_v3-bone_marrow-Lymphocytic_T_CD4/8-lo-Cycling_T|bone_marrow / Manually curated celltypes from each tissue

SMC3 BUB1 ASPM NUF2 SKA1 NCAPH

7.27e-07191736210a0f1a71df2508cbfc73d6868a2122338b9a1c
ToppCellPCW_10-12-Epithelial-Epithelial_proliferating-epi_proliferating2_(13)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

DOCK3 BUB1 ASPM NUF2 SKA1 NCAPH

7.27e-0719173639220f4a345e328f7fa4fd462a0abeea821b3e02
ToppCelldroplet-Lung-21m-Hematologic-lymphocytic-Proliferating_T_cell|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

BUB1 ASPM MASTL NUF2 SKA1 NCAPH

7.27e-0719173645c15f5ce4a207ac944bed65d45f06c1657d1a6d
ToppCellEndothelial-Endothelial-D_(cycle)|Endothelial / shred on cell class and cell subclass (v4)

NSD2 BUB1 ASPM NUF2 SKA1 NCAPH

7.27e-07191736a3c5a913a99f17633c140ec9ece81b73e59e0715
ToppCell3'-GW_trimst-2-LargeIntestine-Mesenchymal-immature_mesenchymal_cell-cycling_stromal|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

BUB1 ASPM CCDC15 NUF2 SKA1 NCAPH

7.27e-0719173650854384fdaa0efa2e3227659d544ed09ac102f2
ToppCellPCW_10-12-Mesenchymal-Mesenchymal_cycling-mes_proliferating2_(11)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

BUB1 ASPM MASTL NUF2 SKA1 NCAPH

7.50e-0719273627723f4e320e49d4a3daafa2d8d3946ff79fab64
ToppCelldroplet-Skin-nan-21m-Epithelial-stem_cell_of_epidermis|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BUB1 ASPM MASTL NUF2 SKA1 NCAPH

7.50e-0719273696f23d6e8604d1cb24910d3118d8171b57c93e14
ToppCellfacs-Thymus-Flowthrough-3m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NSD2 BUB1 ASPM NUF2 SKA1 NCAPH

7.50e-07192736e8d47504b744040a762ec9b670a66cc060b2ae86
ToppCellProliferating|World / shred by cell class for mouse tongue

BUB1 ASPM MASTL NUF2 SKA1 NCAPH

7.50e-07192736f081f3f957cc782294e118fcc1055f6a4264ee98
ToppCellPND07-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-SCMF-SCMF_G2M|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

BUB1 ASPM MASTL NUF2 SKA1 NCAPH

7.73e-07193736a332dfdcc48c405020014e644aa4d14fda98cc86
ToppCelldroplet-Tongue-nan-24m-Epithelial-proliferating|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BUB1 ASPM MASTL NUF2 SKA1 NCAPH

7.73e-07193736f20b90e3f3f5c9a1ae51c5ebe6d3adb954a142f2
ToppCellcontrol-T/NK_proliferative|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

NSD2 BUB1 ASPM NUF2 SKA1 NCAPH

7.73e-07193736ecb4018a47d9a82bb999e0bc8b3dceabd97d1f0d
ToppCellPBMC-Control-Lymphocyte-T/NK-Other_T-T/NK_proliferative|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

NSD2 BUB1 ASPM NUF2 SKA1 NCAPH

7.96e-07194736f39a471293ecc5c5967b00e772b8f48ebc9affbe
ToppCellPCW_13-14-Mesenchymal-Mesenchymal_cycling-mes_proliferating3_(7)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

BUB1 ASPM MASTL NUF2 SKA1 NCAPH

7.96e-07194736f9070035553bc68106a9e0bdf4b507715a138aba
ToppCellControl-Lymphoid_T/NK-T/NK_proliferative|Control / Disease group, lineage and cell class

NSD2 BUB1 ASPM NUF2 SKA1 NCAPH

7.96e-071947369bbb124001fba7450f4639f47f9b720a483e7242
ToppCellPBMC-Control-Lymphocyte-T/NK-Other_T-T/NK_proliferative-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

NSD2 BUB1 ASPM NUF2 SKA1 NCAPH

7.96e-07194736a75ecd0b0a928d4646602f7d16a645f6b3df3af5
ToppCellPBMC-Control-Lymphocyte-T/NK-Other_T-T/NK_proliferative-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

NSD2 BUB1 ASPM NUF2 SKA1 NCAPH

7.96e-0719473617744fd6645cf5a447a01a83f07e8d305c2bcd9c
ToppCell(7)_Epithelial_cells-(7)_Epithelial-J_(AT1-AT2_progenitors)|(7)_Epithelial_cells / Lung cell shreds - cell class (v4) and cell subclass (v4)

BUB1 ASPM MASTL NUF2 SKA1 NCAPH

7.96e-071947364d6ae2b25db11a4ae6dadee83be5c8c05b1225c3
ToppCellPND03-Endothelial-Endothelial_blood-vessel-Microvascular_EC-EPC|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

BUB1 ASPM MASTL NUF2 SKA1 NCAPH

7.96e-071947363a49c7c86036e09a8cd0114988380d04ad1a26fb
ToppCellcontrol-Lymphocytic-Prol._cells|control / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

NSD2 BUB1 ASPM NUF2 SKA1 NCAPH

7.96e-071947364c76508de3291c952386caffda2d559629ba5998
ToppCellPBMC-Control-Lymphocyte-T/NK-Other_T-T/NK_proliferative|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

NSD2 BUB1 ASPM NUF2 SKA1 NCAPH

7.96e-07194736e14f66f7584909621b776292fbd52808273fd2ee
ToppCellDividing_cells|World / Immune cells in Kidney/Urine in Lupus Nephritis

NSD2 BUB1 ASPM NUF2 SKA1 NCAPH

8.21e-0719573679ee423df85aa1631b7bdea74eacaf826dfc4a2c
ToppCellDividing_cells-Dividing_cells|World / Immune cells in Kidney/Urine in Lupus Nephritis

NSD2 BUB1 ASPM NUF2 SKA1 NCAPH

8.21e-0719573619829760dfcc0edafd2a2bd80f424a45d039af1f
ToppCell10x5'-lymph-node_spleen-Lymphocytic_B_plasma-Plasmablasts|lymph-node_spleen / Manually curated celltypes from each tissue

BUB1 ASPM NUF2 SSR3 SKA1 NCAPH

8.21e-071957361390728b9a514db534e8bc6dcf72cf51a1065780
ToppCellfacs-Thymus-nan-3m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NSD2 BUB1 ASPM MASTL NUF2 NCAPH

8.21e-0719573693c345e70d6c8ff5d12fd63d73228c1700b804a0
ToppCellfacs-Marrow-B-cells-3m-Lymphocytic-late_pro-B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NSD2 BUB1 ASPM NUF2 SKA1 NCAPH

8.21e-07195736294c74336fafc1bad237d851efb4a487475078eb
ToppCellPCW_05-06-Mesenchymal-Mesenchymal_cycling|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

BUB1 ASPM MASTL NUF2 SKA1 NCAPH

8.21e-07195736926eb3fc5d028be936885bea0654a77db3107234
ToppCelldroplet-Tongue-TONGUE-1m-Epithelial-proliferating|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BUB1 ASPM MASTL NUF2 SKA1 NCAPH

8.21e-07195736b57132802cb977551e214880984f3edcd375474f
ToppCellPND03-Endothelial-Endothelial_blood-vessel-Microvascular_EC-EPC-EPC_G2M|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

BUB1 ASPM MASTL NUF2 SKA1 NCAPH

8.21e-071957365790b47b0e028e49b99bda8d6d9e80ac79208cdf
ToppCellmild-Lymphocytic-Prol._cells|mild / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

NSD2 BUB1 ASPM NUF2 SKA1 NCAPH

8.21e-071957369a8cc9097a349fd0a53ccf2723ee8bb1418d6aca
ToppCellPCW_05-06-Mesenchymal-Mesenchymal_cycling-mes_proliferating3_(7)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

BUB1 ASPM MASTL NUF2 SKA1 NCAPH

8.21e-071957361a5e814e12fe37287dbfc58189e1958e2c76b5da
ToppCellfacs-Marrow-B-cells-3m-Lymphocytic-late_pro_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NSD2 BUB1 ASPM NUF2 SKA1 NCAPH

8.21e-071957365749ea833be84e262e3d0a4fe1a9a373f0ef545f
ToppCellBrain_organoid-organoid_Paulsen_bioRxiv-3.5_mon-Proliferating-Cycling_Progenitors|3.5_mon / Sample Type, Dataset, Time_group, and Cell type.

BUB1 ASPM MASTL NUF2 SKA1 NCAPH

8.45e-071967365905f0e3061a6b98b7a33d64c782c3dda2cd51ef
ToppCellPCW_07-8.5-Mesenchymal-Mesenchymal_cycling-mes_proliferating3_(7)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

BUB1 ASPM MASTL NUF2 SKA1 NCAPH

8.45e-071967361964c5003a0cb84539850a7cfe3bbb0e23a61d2d
ToppCellmild-Lymphocytic-Prol._cells|Lymphocytic / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

NSD2 BUB1 ASPM NUF2 SKA1 NCAPH

8.45e-07196736b1d9866d5dfaefdb8bedaf01a750d97987acb3d1
ToppCellPCW_07-8.5-Mesenchymal-Mesenchymal_cycling|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

BUB1 ASPM MASTL NUF2 SKA1 NCAPH

8.45e-0719673673f951f7712e0aa3323676b9a4b7944d21d347c4
ToppCellcontrol-Lymphocytic-Prol._cells|Lymphocytic / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

NSD2 BUB1 ASPM NUF2 SKA1 NCAPH

8.45e-07196736886f7c865b086d6ebb4a1746865c30af6bbed345
ComputationalNeighborhood of CDC20

NSD2 BUB1 ASPM NCAPH

9.16e-0556464GNF2_CDC20
ComputationalNeighborhood of CCNB2

NSD2 BUB1 ASPM NCAPH

9.82e-0557464GNF2_CCNB2
DrugCamptothecine (S,+) [7689-03-4]; Down 200; 11.4uM; MCF7; HT_HG-U133A

TRIM33 SCAF8 PLEKHF2 ASPM NCK1 ZIC1 SOS2

2.09e-061847372321_DN
DrugTrichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A

NSD2 UBTF SRC ELK4 SKA1 ZIC1

2.46e-051807364821_DN
DrugCamptothecine (S,+) [7689-03-4]; Down 200; 11.4uM; MCF7; HT_HG-U133A

ACSL3 TRIM33 SCAF8 ASPM NCK1 SOS2

2.62e-051827363887_DN
Drugd 266

UBTF POMC

3.04e-053732CID000048178
DrugAlsterpaullone; Down 200; 10uM; MCF7; HT_HG-U133A

TRIM33 SCAF8 PLEKHF2 ASPM NCK1 NCAPH

3.05e-051877367051_DN
DrugDoxorubicin hydrochloride [25316-40-9]; Down 200; 6.8uM; MCF7; HT_HG-U133A

TRIM33 ZNF273 PLEKHF2 NCK1 PALB2 ZIC1

3.15e-051887363291_DN
DrugPromethazine hydrochloride [58-33-3]; Down 200; 12.4uM; PC3; HT_HG-U133A

NSD2 UBTF OTUB1 BUB1 MCC SOS2

3.24e-051897366717_DN
DrugPargyline hydrochloride [306-07-0]; Down 200; 20.4uM; HL60; HG-U133A

CLUAP1 ZNF273 MATR3 SSR3 NCAPH DNAJC3

3.44e-051917361418_DN
Diseaseprimary autosomal recessive microcephaly (is_implicated_in)

BUB1 ASPM NCAPH

7.31e-0616713DOID:0070296 (is_implicated_in)
Diseasesyndrome (implicated_via_orthology)

NSD2 SCAF8 SCAF4

1.06e-0518713DOID:225 (implicated_via_orthology)
DiseaseLiver carcinoma

GABRD STAB2 BUB1 ASPM NUF2 SKA1 NCAPH YTHDF2

2.96e-05507718C2239176
DiseaseColorectal cancer

SRC BUB1 MCC

3.75e-0527713cv:C0346629
DiseaseCOLORECTAL CANCER

SRC BUB1 MCC

3.75e-0527713114500
DiseaseNeoplasm of the large intestine

SRC BUB1 MCC

3.75e-0527713cv:C0009404
Diseasefactor VIII measurement, coagulation factor measurement

STAB2 ASIC2

5.68e-055712EFO_0004630, EFO_0004634
DiseaseNeurodevelopmental delay

NSD2 CARS1

1.19e-047712C4022738
Diseasedevelopmental disorder of mental health (implicated_via_orthology)

GABRD NAA15 PLXNB2

2.27e-0449713DOID:0060037 (implicated_via_orthology)
Diseasephenylacetylglutamine measurement

SRC RXFP2

3.71e-0412712EFO_0021013
Diseasestomach cancer (is_marker_for)

CALR SRC ASPM NUF2

3.89e-04142714DOID:10534 (is_marker_for)
DiseaseMicrocephaly

NSD2 CARS1 NCAPH

5.73e-0467713C0025958
Diseaselung non-small cell carcinoma (is_marker_for)

CALR NSD2 NUF2 NCAPH

7.48e-04169714DOID:3908 (is_marker_for)
DiseaseX-12063 measurement

ASIC2 MATR3 SKA1 DNAH5

1.07e-03186714EFO_0021283
Diseaselung adenocarcinoma (is_marker_for)

SRC NUF2 PLOD2

1.14e-0385713DOID:3910 (is_marker_for)
Diseaseintestinal permeability measurement

STAB2 ASIC2

1.79e-0326712EFO_0011031
Diseasethrombocytopenia (is_implicated_in)

SRC MASTL

1.93e-0327712DOID:1588 (is_implicated_in)
DiseaseHuntington disease, disease progression measurement

KIF9 ST8SIA6

2.38e-0330712EFO_0008336, MONDO_0007739

Protein segments in the cluster

PeptideGeneStartEntry
HIVKVVAKKYRNFDI

CLIC4

196

Q9Y696
QLVYAHKKVNKSKVT

ANKRD30B

1316

Q9BXX2
RQKLKKVFQQHYTNK

BUB1

1051

O43683
VILHFKNKYHENKKL

CALR3

146

Q96L12
KVVDKFIKQRDYHQQ

COG4

316

Q9H9E3
KFQINYDKHIKVNKK

GVINP1

1941

Q7Z2Y8
KKIIQNKKTCVEYKH

MASTL

456

Q96GX5
ELIVKHKFTKAYKSV

AOPEP

751

Q8N6M6
KRCFAHYKQVKKLNK

DNAJC3

256

Q13217
HYKQVKKLNKLIESA

DNAJC3

261

Q13217
QHKEYLNLKKTAIKI

ASPM

2086

Q8IZT6
KYRANKKKQKVFQHN

ASPM

2586

Q8IZT6
ALRQKANFKHYKPKQ

ASIC2

136

Q16515
KAKLYHKQRHAEKIQ

NSA2

46

O95478
EKVHKYNLAVTDKLK

RASSF3

56

Q86WH2
VKVAIKDKQVKYFIH

MORF4L1

31

Q9UBU8
IDYIQFLHKEKKKQE

MLX

181

Q9UH92
HYQKLKKFLNKLAEE

MATR3

826

P43243
LLQSKEEKKYHSQKQ

KIAA0895

111

Q8NCT3
KNKHFKVQLKETVYC

NCK1

326

P16333
HLKYFSQKQDVVLIK

DST

6661

Q03001
LYKLFKAIKHQVEKG

PLXNB2

1421

O15031
QFKINKKHEDVKQYK

NUF2

356

Q9BZD4
KLKGQKKSARQYHVQ

NSD2

251

O96028
VTLFKNAIIKNAYKK

POMC

251

P01189
AHFNADYRKKQKAKV

GABRD

331

O14764
NAKVKIEQKHNYLKT

KIF9

766

Q9HAQ2
FLVKAKIYKHAGNIK

NAA15

411

Q9BXJ9
LKKFQKANHKVVFAA

PLOD2

126

O00469
YQHEKLFIQVKGKKS

PALB2

551

Q86YC2
NIYQQKIKDLHKKYS

OTUB1

66

Q96FW1
NLVAAYEKAKKKHQN

MCC

771

P23508
KPAKIDHKQYFRKQV

IGSF10

2036

Q6WRI0
KQLYVKHKVDLFYKL

DOCK3

101

Q8IZD9
IIKKVNGQKFVYKFV

ELK4

71

P28324
QKHKTFVEKYEKQIK

CDC37

146

Q16543
TKKVHVIFNYKGKNV

CALR

141

P27797
FSIHLKQKPKYVKFQ

CCDC168

926

Q8NDH2
KTYKRKSVKFQNHIS

ERCC6L2

1341

Q5T890
KAAIKAIKLYKHVVQ

SCAF4

31

O95104
KAAIKAIKFYKHVVQ

SCAF8

31

Q9UPN6
IKLKQEYQLCFHKTK

DNAH5

436

Q8TE73
NIVIQKKKYNKQHII

PLEKHF2

66

Q9H8W4
YVQKEKQKVVSAVKH

SFI1

266

A8K8P3
NAKGLNVKHYKIRKL

SRC

196

P12931
VKKKLQKKHSQHYQI

TRIM33

1006

Q9UPN9
LKKYSHVNKKALDQF

SMC3

976

Q9UQE7
SQDHFKKYLVKLKSI

SOS2

906

Q07890
NKNFYDKKTAIHKAL

CARS1

491

P49589
KEINKAVISKYKILH

SKA1

166

Q96BD8
YEKTHVCNLKKFKVF

MKLN1

76

Q9UL63
LKNDYNKETFTLKHK

MKLN1

106

Q9UL63
HSLYLKVKGNVFKNK

RPL19

121

P84098
KARQKVLFFHPKYLK

ST8SIA6

291

P61647
VFIKYTKLKKIFLQH

RXFP2

156

Q8WXD0
KHQIKQAVKKLYDID

RPL23A

106

P62750
AYKNVKFVLKHKVAQ

SSR3

76

Q9UNL2
VFTYAKNKFKNKRLL

ACSL3

91

O95573
KQEALKHFQKQVKYR

CCDC15

76

Q0P6D6
LKKQLYNIYAKHTKQ

CLPP

201

Q16740
QKVNKIEIHYAKTAK

NCAPH

626

Q15003
KAHIKLNTKKLYQAD

CLUAP1

76

Q96AJ1
KIFQCDKYVKVLHKF

ZNF273

176

Q14593
HFAEQIAKAKFIVKK

RTCA

326

O00442
KVQKLQEKIYFALQH

RORB

391

Q92753
SDYKKKKHVFKLQTQ

SPTBN4

2486

Q9H254
QDNKDKLKEYLKFHV

STAB2

1801

Q8WWQ8
EKVLSHKQAHVQYKK

ZNF630

241

Q2M218
VKVFHKYSNAKRHKI

ZNF708

146

P17019
KPFKAKYKLVNHIRV

ZIC1

281

Q15915
AIHLKKLNFLKSQKY

ZBTB49

306

Q6ZSB9
KKLAEEQQKQYKVHL

UBTF

616

P17480
SKIFQCDKYVKVFHK

ZNF680

151

Q8NEM1
KKVFTYKANLKEHQR

ZSCAN5C

446

A6NGD5
IQRFHKYDAFKKNLK

ZNF300

181

Q96RE9
KAKQVLKIIASYKHT

YTHDF2

536

Q9Y5A9
HQVEIKVYKQKVKHL

GAS8

91

O95995
KVYKQKVKHLLYEHQ

GAS8

96

O95995