Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyBiologicalProcess	mitotic actomyosin contractile ring assembly	IQGAP3 IQGAP1	5.38e-05	3	88	2	GO:1903475
GeneOntologyBiologicalProcess	mitotic actomyosin contractile ring assembly actin filament organization	IQGAP3 IQGAP1	5.38e-05	3	88	2	GO:1903479
GeneOntologyBiologicalProcess	assembly of actomyosin apparatus involved in mitotic cytokinesis	IQGAP3 IQGAP1	5.38e-05	3	88	2	GO:1902407
Domain	RasGAP_C	IQGAP3 IQGAP1	6.56e-05	3	88	2	IPR000593
Domain	RasGAP_C	IQGAP3 IQGAP1	6.56e-05	3	88	2	PF03836
Domain	Anion_exchange	SLC4A7 SLC4A10	2.17e-04	5	88	2	IPR001717
Domain	CH	GAS2L3 SYNE2 IQGAP3 IQGAP1	2.50e-04	65	88	4	SM00033
Domain	CH	GAS2L3 SYNE2 IQGAP3 IQGAP1	3.33e-04	70	88	4	PF00307
Domain	IQ	LRRIQ1 MYO18B IQGAP3 IQGAP1	3.51e-04	71	88	4	PF00612
Domain	-	GAS2L3 SYNE2 IQGAP3 IQGAP1	3.51e-04	71	88	4	1.10.418.10
Domain	CH	GAS2L3 SYNE2 IQGAP3 IQGAP1	3.91e-04	73	88	4	PS50021
Domain	CH-domain	GAS2L3 SYNE2 IQGAP3 IQGAP1	4.33e-04	75	88	4	IPR001715
Domain	ANION_EXCHANGER_2	SLC4A7 SLC4A10	4.54e-04	7	88	2	PS00220
Domain	ANION_EXCHANGER_1	SLC4A7 SLC4A10	4.54e-04	7	88	2	PS00219
Domain	IQ	LRRIQ1 MYO18B IQGAP3 IQGAP1	5.81e-04	81	88	4	SM00015
Domain	Band3_cytoplasmic_dom	SLC4A7 SLC4A10	7.73e-04	9	88	2	IPR013769
Domain	Band_3_cyto	SLC4A7 SLC4A10	7.73e-04	9	88	2	PF07565
Domain	-	SLC4A7 SLC4A10	7.73e-04	9	88	2	3.40.1100.10
Domain	DUF1220	NBPF4 NBPF6	7.73e-04	9	88	2	SM01148
Domain	IQ_motif_EF-hand-BS	LRRIQ1 MYO18B IQGAP3 IQGAP1	8.63e-04	90	88	4	IPR000048
Domain	HCO3_cotransp	SLC4A7 SLC4A10	9.64e-04	10	88	2	PF00955
Domain	HCO3_transpt_C	SLC4A7 SLC4A10	9.64e-04	10	88	2	IPR011531
Domain	PTrfase/Anion_transptr	SLC4A7 SLC4A10	9.64e-04	10	88	2	IPR016152
Domain	HCO3_transpt_euk	SLC4A7 SLC4A10	9.64e-04	10	88	2	IPR003020
Domain	IQ	LRRIQ1 MYO18B IQGAP3 IQGAP1	9.76e-04	93	88	4	PS50096
Domain	NBPF_dom	NBPF4 NBPF6	1.17e-03	11	88	2	IPR010630
Domain	NBPF	NBPF4 NBPF6	1.17e-03	11	88	2	PS51316
Domain	DUF1220	NBPF4 NBPF6	1.17e-03	11	88	2	PF06758
Domain	RasGAP	IQGAP3 IQGAP1	1.93e-03	14	88	2	SM00323
Domain	RasGAP_CS	IQGAP3 IQGAP1	1.93e-03	14	88	2	IPR023152
Domain	RasGAP	IQGAP3 IQGAP1	2.21e-03	15	88	2	PF00616
Domain	RAS_GTPASE_ACTIV_1	IQGAP3 IQGAP1	2.21e-03	15	88	2	PS00509
Domain	RAS_GTPASE_ACTIV_2	IQGAP3 IQGAP1	2.21e-03	15	88	2	PS50018
Domain	-	IQGAP3 IQGAP1	2.52e-03	16	88	2	1.10.506.10
Domain	RasGAP_dom	IQGAP3 IQGAP1	3.20e-03	18	88	2	IPR001936
Domain	Myosin-like_IQ_dom	MYO18B IQGAP1	3.56e-03	19	88	2	IPR027401
Domain	-	MYO18B IQGAP1	3.56e-03	19	88	2	4.10.270.10
Pubmed	MAP4K3/GLK Promotes Lung Cancer Metastasis by Phosphorylating and Activating IQGAP1.	MAP4K3 IQGAP1	7.38e-06	2	95	2	31431460
Pubmed	Gene signatures and prognostic analyses of the Tob/BTG pituitary tumor-transforming gene (PTTG) family in clinical breast cancer patients.	PTTG3P PTTG1	7.38e-06	2	95	2	33173433
Pubmed	IQGAP1 modulates activation of B-Raf.	BRAF IQGAP1	7.38e-06	2	95	2	17563371
Pubmed	The lncRNA PTTG3P promotes the progression of CRPC via upregulating PTTG1.	PTTG3P PTTG1	7.38e-06	2	95	2	33743960
Pubmed	Chronic continuous hypoxia decreases the expression of SLC4A7 (NBCn1) and SLC4A10 (NCBE) in mouse brain.	SLC4A7 SLC4A10	7.38e-06	2	95	2	17928512
Pubmed	The long non-coding RNA PTTG3P promotes cell growth and metastasis via up-regulating PTTG1 and activating PI3K/AKT signaling in hepatocellular carcinoma.	PTTG3P PTTG1	7.38e-06	2	95	2	29803224
Pubmed	Regulation of ERK3/MAPK6 expression by BRAF.	BRAF MAPK6	7.38e-06	2	95	2	16964379
Pubmed	Mice lacking pituitary tumor transforming gene show testicular and splenic hypoplasia, thymic hyperplasia, thrombocytopenia, aberrant cell cycle progression, and premature centromere division.	PTTG3P PTTG1	2.21e-05	3	95	2	11682618
Pubmed	PTTG is a secretory protein in human pituitary adenomas and in mouse pituitary tumor cell lines.	PTTG3P PTTG1	2.21e-05	3	95	2	17652795
Pubmed	Pituitary Tumor Transforming Gene 1 Orchestrates Gene Regulatory Variation in Mouse Ventral Midbrain During Aging.	PTTG3P PTTG1	2.21e-05	3	95	2	33173537
Pubmed	PTTG1 Reprograms Asparagine Metabolism to Promote Hepatocellular Carcinoma Progression.	PTTG3P PTTG1	2.21e-05	3	95	2	37159932
Pubmed	Pttg1/securin is required for the branching morphogenesis of the mammary gland and suppresses mammary tumorigenesis.	PTTG3P PTTG1	2.21e-05	3	95	2	24395789
Pubmed	The lifespan quantitative trait locus gene Securin controls hematopoietic progenitor cell function.	PTTG3P PTTG1	2.21e-05	3	95	2	31073078
Pubmed	A prometaphase mechanism of securin destruction is essential for meiotic progression in mouse oocytes.	PTTG3P PTTG1	2.21e-05	3	95	2	34262048
Pubmed	Pituitary tumor transforming gene as a novel regulatory factor of liver fibrosis.	PTTG3P PTTG1	2.21e-05	3	95	2	25936962
Pubmed	The biology of IQGAP proteins: beyond the cytoskeleton.	IQGAP3 IQGAP1	2.21e-05	3	95	2	25722290
Pubmed	Mad2 is required for inhibiting securin and cyclin B degradation following spindle depolymerisation in meiosis I mouse oocytes.	PTTG3P PTTG1	2.21e-05	3	95	2	16322543
Pubmed	PTTG1 alleviates acute alcoholic liver injury by inhibiting endoplasmic reticulum stress-induced hepatocyte pyroptosis.	PTTG3P PTTG1	2.21e-05	3	95	2	36737842
Pubmed	Discordant proliferation and differentiation in pituitary tumor-transforming gene-null bone marrow stem cells.	PTTG3P PTTG1	2.21e-05	3	95	2	17626243
Pubmed	Pituitary tumor transforming gene: an update.	PTTG3P PTTG1	2.21e-05	3	95	2	15281346
Pubmed	Pituitary senescence: the evolving role of Pttg.	PTTG3P PTTG1	2.21e-05	3	95	2	20153804
Pubmed	IQGAP proteins reveal an atypical phosphoinositide (aPI) binding domain with a pseudo C2 domain fold.	IQGAP3 IQGAP1	2.21e-05	3	95	2	22493426
Pubmed	Securin and not CDK1/cyclin B1 regulates sister chromatid disjunction during meiosis II in mouse eggs.	PTTG3P PTTG1	2.21e-05	3	95	2	18639540
Pubmed	Pituitary tumor transforming gene (PTTG) transforming and transactivation activity.	PTTG3P PTTG1	2.21e-05	3	95	2	10713046
Pubmed	Involvement of IQGAP family proteins in the regulation of mammalian cell cytokinesis.	IQGAP3 IQGAP1	2.21e-05	3	95	2	25229330
Pubmed	Aromatase, CYP1B1 and fatty acid synthase expression in breast tumors of BRCA1 mutation carriers.	CYP1B1 FASN	2.21e-05	3	95	2	19083124
Pubmed	Role of Nesprin-2 and RanBP2 in BICD2-associated brain developmental disorders.	RANBP2 SYNE2	2.21e-05	3	95	2	36930595
Pubmed	Pituitary tumor transforming gene-null male mice exhibit impaired pancreatic beta cell proliferation and diabetes.	PTTG3P PTTG1	2.21e-05	3	95	2	12626748
Pubmed	Maternal age-dependent APC/C-mediated decrease in securin causes premature sister chromatid separation in meiosis II.	PTTG3P PTTG1	2.21e-05	3	95	2	28516917
Pubmed	Sex-steroid milieu determines diabetes rescue in pttg-null mice.	PTTG3P PTTG1	2.21e-05	3	95	2	16731783
Pubmed	Mechanisms for growth factor-induced pituitary tumor transforming gene-1 expression in pituitary folliculostellate TtT/GF cells.	PTTG3P PTTG1	2.21e-05	3	95	2	16959877
Pubmed	Characterization of the murine pituitary tumor transforming gene (PTTG) and its promoter.	PTTG3P PTTG1	2.21e-05	3	95	2	10650958
Pubmed	Regulation of pituitary tumor transforming gene (PTTG) expression and phosphorylation in thyroid cells.	PTTG3P PTTG1	2.21e-05	3	95	2	23867215
Pubmed	Characterization of the pituitary tumor transforming gene 1 knockout mouse retina.	PTTG3P PTTG1	2.21e-05	3	95	2	21203837
Pubmed	Murine pituitary tumor-transforming gene functions as a securin protein in insulin-secreting cells.	PTTG3P PTTG1	2.21e-05	3	95	2	17065388
Pubmed	A novel gene family NBPF: intricate structure generated by gene duplications during primate evolution.	NBPF4 NBPF6 NBPF5P	2.53e-05	21	95	3	16079250
Pubmed	Multiplexed kinase interactome profiling quantifies cellular network activity and plasticity.	BLK SMG1 BRAF MAP4K3 RALBP1 CIBAR2 TIMM29 MAPK6 GNL1 DARS2 AXIN1	3.91e-05	910	95	11	36736316
Pubmed	Pituitary hypoplasia in Pttg-/- mice is protective for Rb+/- pituitary tumorigenesis.	PTTG3P PTTG1	4.41e-05	4	95	2	15919720
Pubmed	Anaphase B precedes anaphase A in the mouse egg.	PTTG3P PTTG1	4.41e-05	4	95	2	22342753
Pubmed	Securin and separase phosphorylation act redundantly to maintain sister chromatid cohesion in mammalian cells.	PTTG3P PTTG1	4.41e-05	4	95	2	16030258
Pubmed	Degradation of securin in mouse and pig oocytes is dependent on ubiquitin-proteasome pathway and is required for proteolysis of the cohesion subunit, Rec8, at the metaphase-to-anaphase transition.	PTTG3P PTTG1	4.41e-05	4	95	2	16720305
Pubmed	The pituitary tumor-transforming gene promotes angiogenesis in a mouse model of follicular thyroid cancer.	PTTG3P PTTG1	4.41e-05	4	95	2	17127711
Pubmed	Tumor suppressor activity of KLF6 mediated by downregulation of the PTTG1 oncogene.	PTTG3P PTTG1	4.41e-05	4	95	2	20116377
Pubmed	Pituitary tumor transforming gene 1 induces tumor necrosis factor-α production from keratinocytes: implication for involvement in the pathophysiology of psoriasis.	PTTG3P PTTG1	4.41e-05	4	95	2	23677169
Pubmed	A SCL4A10 gene product maps selectively to the basolateral plasma membrane of choroid plexus epithelial cells.	SLC4A7 SLC4A10	4.41e-05	4	95	2	14592810
Pubmed	Preimplantation mouse embryos depend on inhibitory phosphorylation of separase to prevent chromosome missegregation.	PTTG3P PTTG1	4.41e-05	4	95	2	19124608
Pubmed	Induction of Dlk1 by PTTG1 inhibits adipocyte differentiation and correlates with malignant transformation.	PTTG3P PTTG1	4.41e-05	4	95	2	19477929
Pubmed	The pituitary tumour-transforming gene 1/delta-like homologue 1 pathway plays a key role in liver fibrogenesis.	PTTG3P PTTG1	4.41e-05	4	95	2	35050550
Pubmed	Securin is not required for cellular viability, but is required for normal growth of mouse embryonic fibroblasts.	PTTG3P PTTG1	4.41e-05	4	95	2	11516952
Pubmed	Valosin-containing protein (VCP) is a novel IQ motif-containing GTPase activating protein 1 (IQGAP1)-interacting protein.	IQGAP3 IQGAP1	4.41e-05	4	95	2	28970065
Pubmed	Tumorigenic potential of pituitary tumor transforming gene (PTTG) in vivo investigated using a transgenic mouse model, and effects of cross breeding with p53 (+/-) transgenic mice.	PTTG3P PTTG1	4.41e-05	4	95	2	23164239
Pubmed	Abnormal megakaryocyte development and platelet function in Nbeal2(-/-) mice.	PTTG3P PTTG1	4.41e-05	4	95	2	23861251
Pubmed	Spatial learning and long-term memory impairments in RasGrf1 KO, Pttg1 KO, and double KO mice.	PTTG3P PTTG1	4.41e-05	4	95	2	30259712
Pubmed	Expression of PTTG and prc1 genes during telencephalic neurogenesis.	PTTG3P PTTG1	4.41e-05	4	95	2	10727870
Pubmed	Pituitary tumor-transforming gene 1 regulates the patterning of retinal mosaics.	PTTG3P PTTG1	4.41e-05	4	95	2	24927528
Pubmed	The selective continued linkage of centromeres from mitosis to interphase in the absence of mammalian separase.	PTTG3P PTTG1	4.41e-05	4	95	2	16533944
Pubmed	Separase: a universal trigger for sister chromatid disjunction but not chromosome cycle progression.	PTTG3P PTTG1	4.41e-05	4	95	2	16533945
Pubmed	Aberrant accumulation of PTTG1 induced by a mutated thyroid hormone beta receptor inhibits mitotic progression.	PTTG3P PTTG1	4.41e-05	4	95	2	17039256
Pubmed	Transcriptional profiling reveals functional links between RasGrf1 and Pttg1 in pancreatic beta cells.	PTTG3P PTTG1	4.41e-05	4	95	2	25421944
Pubmed	A single amino acid substitution (Cys249Trp) in Crb1 causes retinal degeneration and deregulates expression of pituitary tumor transforming gene Pttg1.	PTTG3P PTTG1	4.41e-05	4	95	2	17234588
Pubmed	Homologue disjunction in mouse oocytes requires proteolysis of securin and cyclin B1.	PTTG3P PTTG1	4.41e-05	4	95	2	14593421
Pubmed	Securin regulates entry into M-phase by modulating the stability of cyclin B.	PTTG3P PTTG1	4.41e-05	4	95	2	18364698
Pubmed	Glypican-1 regulates anaphase promoting complex/cyclosome substrates and cell cycle progression in endothelial cells.	PTTG3P PTTG1	4.41e-05	4	95	2	18417614
Pubmed	Immunocytochemical identification of electroneutral Na⁺-coupled HCO₃⁻ transporters in freshly dissociated mouse medullary raphé neurons.	SLC4A7 SLC4A10	7.34e-05	5	95	2	23500099
Pubmed	p21(Cip1) restrains pituitary tumor growth.	PTTG3P PTTG1	7.34e-05	5	95	2	18981426
Pubmed	MEIKIN expression and its C-terminal phosphorylation by PLK1 is closely related the metaphase-anaphase transition by affecting cyclin B1 and Securin stabilization in meiotic oocyte.	PTTG3P PTTG1	7.34e-05	5	95	2	39093409
Pubmed	Targeting mitotic exit leads to tumor regression in vivo: Modulation by Cdk1, Mastl, and the PP2A/B55α,δ phosphatase.	PTTG3P PTTG1	7.34e-05	5	95	2	21156286
Pubmed	PTTG-binding factor (PBF) is a novel regulator of the thyroid hormone transporter MCT8.	PTTG3P PTTG1	7.34e-05	5	95	2	22535767
Pubmed	Smurf1 targets Securin for ubiquitin-dependent degradation and regulates the metaphase-to-anaphase transition.	PTTG3P PTTG1	7.34e-05	5	95	2	28658604
Pubmed	Senescence mediates pituitary hypoplasia and restrains pituitary tumor growth.	PTTG3P PTTG1	7.34e-05	5	95	2	17975001
Pubmed	The meiosis I-to-meiosis II transition in mouse oocytes requires separase activity.	PTTG3P PTTG1	7.34e-05	5	95	2	14561405
Pubmed	The Rae1-Nup98 complex prevents aneuploidy by inhibiting securin degradation.	PTTG3P PTTG1	7.34e-05	5	95	2	16355229
Pubmed	Altered expression of securin (Pttg1) and serpina3n in the auditory system of hearing-impaired Tff3-deficient mice.	PTTG3P PTTG1	7.34e-05	5	95	2	21076990
Pubmed	Systematic proteomics of endogenous human cohesin reveals an interaction with diverse splicing factors and RNA-binding proteins required for mitotic progression.	PHF2 RANBP2 FASN ZNF608 ZDBF2 IQGAP1	1.05e-04	272	95	6	31010829
Pubmed	Involvement of histone deacetylase 1/2 in adrenocorticotropic hormone synthesis and proliferation of corticotroph tumor AtT-20 cells.	PTTG3P PTTG1	1.10e-04	6	95	2	33181265
Pubmed	Early Hearing Loss upon Disruption of Slc4a10 in C57BL/6 Mice.	SLC4A7 SLC4A10	1.10e-04	6	95	2	31001720
Pubmed	mTOR promotes pituitary tumor development through activation of PTTG1.	PTTG3P PTTG1	1.10e-04	6	95	2	27524416
Pubmed	Function of COP9 signalosome in regulation of mouse oocytes meiosis by regulating MPF activity and securing degradation.	PTTG3P PTTG1	1.10e-04	6	95	2	21991377
Pubmed	Proteotyping of knockout mouse strains reveals sex- and strain-specific signatures in blood plasma.	PTTG3P PTTG1 IQGAP1	1.11e-04	34	95	3	34050187
Pubmed	Common variants at 2q37.3, 8q24.21, 15q21.3 and 16q24.1 influence chronic lymphocytic leukemia risk.	LRATD2 CPEB1	1.54e-04	7	95	2	20062064
Pubmed	Loss of Cdc20 causes a securin-dependent metaphase arrest in two-cell mouse embryos.	PTTG3P PTTG1	1.54e-04	7	95	2	17325031
Pubmed	IQGAP1 integrates Ca2+/calmodulin and B-Raf signaling.	BRAF IQGAP1	1.54e-04	7	95	2	18567582
Pubmed	Generation and annotation of the DNA sequences of human chromosomes 2 and 4.	RANBP2 UBE2F SLC4A10 POLR1B WDFY3 FREM3 MAP3K19	2.16e-04	442	95	7	15815621
Pubmed	Identification of disease-relevant modulators of the SHH pathway in the developing brain.	PTTG3P PTTG1	2.62e-04	9	95	2	34463328
Pubmed	Nuclear pore protein NUP88 activates anaphase-promoting complex to promote aneuploidy.	PTTG3P PTTG1	3.28e-04	10	95	2	26731471
Pubmed	Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.	PHF2 SMG1 ZNF608 SYNE2 WDFY3	3.91e-04	225	95	5	12168954
Pubmed	Study of the common genetic background for rheumatoid arthritis and systemic lupus erythematosus.	BLK PTTG1	4.00e-04	11	95	2	21068098
Pubmed	Identification of additional transcripts in the Williams-Beuren syndrome critical region.	SPDYE1 NSUN5	4.00e-04	11	95	2	12073013
Pubmed	Separase phosphosite mutation leads to genome instability and primordial germ cell depletion during oogenesis.	PTTG3P PTTG1	4.00e-04	11	95	2	21494564
Pubmed	A dual-color FISH gene map of the proximal region of rat Chromosome 4 and comparative analysis in human and mouse.	DMTF1 BRAF	4.00e-04	11	95	2	11707776
Pubmed	A human skeletal muscle interactome centered on proteins involved in muscular dystrophies: LGMD interactome.	SMG1 RANBP2 ANK2 RALBP1 SYNE2 ZNF407 MYO18B	4.37e-04	497	95	7	23414517
Pubmed	De novo genic mutations among a Chinese autism spectrum disorder cohort.	PHF2 WDFY3	4.79e-04	12	95	2	27824329
Pubmed	Severe neurologic impairment in mice with targeted disruption of the electrogenic sodium bicarbonate cotransporter NBCe2 (Slc4a5 gene).	SLC4A7 SLC4A10	4.79e-04	12	95	2	21705333
Pubmed	IQGAP3 regulates cell proliferation through the Ras/ERK signalling cascade.	IQGAP3 IQGAP1	4.79e-04	12	95	2	18604197
Pubmed	Binding of USP4 to cortactin enhances cell migration in HCT116 human colon cancer cells.	CACTIN RANBP2 FASN SWAP70	5.56e-04	137	95	4	37039823
Pubmed	Identification and characterization of nardilysin as a novel dimethyl H3K4-binding protein involved in transcriptional regulation.	PHF2 IQGAP1	5.65e-04	13	95	2	22294699
Pubmed	A genome-wide association study for reading and language abilities in two population cohorts.	NLRP3 NOS1AP	5.65e-04	13	95	2	23738518
Pubmed	Systems biology of the 2-cell mouse embryo.	TACC2 CPEB1	5.65e-04	13	95	2	15237213
Pubmed	Specificity and Redundancy of Profilin 1 and 2 Function in Brain Development and Neuronal Structure.	PTTG3P PTTG1	5.65e-04	13	95	2	34571959
Pubmed	Diminished pancreatic beta-cell mass in securin-null mice is caused by beta-cell apoptosis and senescence.	PTTG3P PTTG1	5.65e-04	13	95	2	19213844
Cytoband	1p13.3	NBPF4 NBPF6 NBPF5P	4.07e-04	69	95	3	1p13.3
Cytoband	16q24	BANP CBFA2T3	5.65e-04	17	95	2	16q24
GeneFamily	Neuroblastoma breakpoint family	NBPF4 NBPF6 NBPF5P	6.79e-05	23	63	3	662
ToppCell	mild-low-quality_cells\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	DMTF1 SMG1 CWF19L2 SLC4A7 BRAF SYNE2 ZNF407 USP9Y	1.11e-08	199	95	8	f0b0097df0026496470a80d8cc9375ffd8389b00
ToppCell	3'_v3-bone_marrow-Lymphocytic_B-Pro-B\|bone_marrow / Manually curated celltypes from each tissue	BLK AEBP1 KIF26A CBFA2T3 ARHGEF17 MAP3K19	1.06e-06	156	95	6	b093dbba6662e4fffc8aa577587b77f64ac44b56
ToppCell	droplet-Heart-nan-18m\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CYP1B1 CFD FASN SLC4A10 PODN RAB44	2.01e-06	174	95	6	cf4e0567f2a4ebe5534046b1c091af59b55bdc4f
ToppCell	COVID-19_Moderate-B_intermediate\|COVID-19_Moderate / disease group, cell group and cell class	BLK SOX5 TRIM2 ANK2 ZNF608 SWAP70	2.21e-06	177	95	6	68e3d12a0c048a2d0f1b9680c7338a35855bba30
ToppCell	droplet-Marrow-nan-3m\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SMG1 MIA2 ZNF608 SLF2 CBFA2T3 IQGAP1	2.77e-06	184	95	6	1154a5ad7b8512272b7476f949ddac350910bfb7
ToppCell	renal_papilla_nuclei-Adult_normal_reference\|renal_papilla_nuclei / Celltypes from Cells and Nuclei per compartment and clinical group	SOX5 CYP1B1 ANK2 ZNF608 RALBP1 USP9Y	3.54e-06	192	95	6	6c106b91e46eabbe686a52a65a9c94ad9cbe9390
ToppCell	IPF-Multiplet-Multiplet\|World / Disease state, Lineage and Cell class	SOX5 TRIM2 LRRIQ1 SYNE2 CIBAR2 TACC2	3.87e-06	195	95	6	21dbdc803c6947024dc2416e9e21c2ef0af9bc31
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	TRIM2 SLC4A7 ANK2 RALBP1 TACC2 NOS1AP	3.99e-06	196	95	6	c7136b1c83bcf907eec3b02b151fa061298b6672
ToppCell	mild-low-quality_cells\|mild / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	SMG1 CWF19L2 FAM153A SLC4A7 SYNE2 USP9Y	4.11e-06	197	95	6	e4331969bd911d1ebb5453f40a7057297b5389b4
ToppCell	Influenza-Influenza_Severe-Lymphocyte-T/NK-CD4+_T_naive\|Influenza_Severe / Disease, condition lineage and cell class	ANKRD31 FAM153B FAM153A TRIM2 AEBP1 LRATD2	4.48e-06	200	95	6	0382f8fc27d18003761725e714beb6b3f3150057
ToppCell	Posterior_cortex-Neuronal-Excitatory-eN1(Slc17a7)-eN1_1-Bcl6\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	DCHS2 LRRIQ1 CCDC87 LRATD2 ZDBF2	1.44e-05	144	95	5	08005be9e3367f78ef27e125d9cce5ca53f4bd2d
ToppCell	severe_influenza-CD4+_T_naive\|severe_influenza / disease group, cell group and cell class (v2)	ANKRD31 FAM153B FAM153A AEBP1 LRATD2	2.25e-05	158	95	5	ff3fa4bd06e01363429aec4bb587b95819bf0fc9
ToppCell	Int-URO-Lymphocyte-T_NK-Treg\|Int-URO / Disease, Lineage and Cell Type	SYNE2 SKOR1 LRATD2 PRAP1 ZDBF2	2.25e-05	158	95	5	457d64dceedb67bfff1303334cda1253a839b3d6
ToppCell	10x5'-blood-Lymphocytic_T_CD4-T_CD4/CD8\|blood / Manually curated celltypes from each tissue	SMG1 RANBP2 BRAF SYNE2 USP9Y	2.54e-05	162	95	5	b4535bcb3f469bc139e73f1122f4070013e5a1de
ToppCell	Fetal_29-31_weeks-Epithelial-club_cell-D062\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	FAM153B TRIM2 ZNF608 TACC2 NOS1AP	2.54e-05	162	95	5	5c9bc3c3857a99d8a3caf359a7eb279ce9cc1c81
ToppCell	normal-na-Lymphocytic_B-B_atypical-male\|normal / PBMC cell types (v2) per disease, treatment status, and sex	BLK SOX5 TRIM2 ZNF608 TTLL11	2.85e-05	166	95	5	30a180b67572c3f4fb3a291f271f855e1b20005e
ToppCell	3'_v3-lymph-node_spleen-Lymphocytic_T_CD4-T_CD4/CD8\|lymph-node_spleen / Manually curated celltypes from each tissue	SMG1 RANBP2 BRAF SYNE2 ZNF407	3.29e-05	171	95	5	2e9a20f8980b78325c52065a9c14ab3656267c05
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_B-B_cell-B_c04-SOX5-TNFRSF1B\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	BLK SOX5 ANK2 SWAP70 AEBP1	3.29e-05	171	95	5	a2938e56cb5749004317798dc7ac0f0c2d4d8ae0
ToppCell	5'-Parenchyma_lung-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.2.1\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	FAM153B CIBAR2 ZDBF2 FAM171B C6orf52	3.57e-05	174	95	5	e2243f1e48e3275753a2b3a69d06eefce69a8ded
ToppCell	PND07-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-VEC-VEC_G2M\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CYP1B1 ZNF521 IQGAP3 AXIN1 WDR24	3.57e-05	174	95	5	6c36d607c48267a75ab4da6fb2fe3f931d1b3b52
ToppCell	facs-Trachea-3m-Epithelial-airway_epithelial-tracheobronchial_ciliated_cell-ciliated_cell\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CDH26 LRRIQ1 CCDC87 CIBAR2 IL22RA1	3.87e-05	177	95	5	3cfde67b93f3986312f5e74e42504214d966e7dc
ToppCell	facs-Trachea-3m-Epithelial-airway_epithelial-tracheobronchial_ciliated_cell\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CDH26 LRRIQ1 CCDC87 CIBAR2 IL22RA1	3.87e-05	177	95	5	12a52a12a87a31e501ced611f46a90d172ca7e35
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22-Lymphocytic-Lymphocytic_B-B_cell-B_c02-MS4A1-CD27\|Severe-critical_progression_d12-22 / Compartment, severity and other cell annotations on 10x 3' data (130k)	BLK SOX5 SWAP70 PRAP1 CBFA2T3	4.09e-05	179	95	5	a28a1de500a74c6dcc43481abf9ec0f7e7a300a9
ToppCell	facs-Trachea-nan-3m-Epithelial-ciliated_columnar_cell_of_tracheobronchial_tree\|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CDH26 LRRIQ1 CCDC87 CIBAR2 IL22RA1	4.20e-05	180	95	5	cf6e9f757afeb342c5023f6e6152a1b4d0d164b4
ToppCell	5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-Adventitial_fibroblasts_L.2.1.2.2\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CFD ANK2 AEBP1 ZNF521 PODN	4.54e-05	183	95	5	06a68fa2be36448064f4668be24a5b85ad85c6e8
ToppCell	PBMC-Control-Lymphocyte-B-B_cell-B_intermediate-B_intermediate-10\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	BLK SOX5 ANK2 ZNF608 SWAP70	4.54e-05	183	95	5	01664fce6b70a02c9d39d747b6a6aabc86d57bc2
ToppCell	5'-Adult-Distal_Rectal-Mesenchymal-fibroblastic-mLN_Stroma_(FMO2+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CFD ANK2 AEBP1 PODN ARHGEF17	4.78e-05	185	95	5	9faa35ceb89ccd2979072286f063687c9f846ce3
ToppCell	Adult-Mesenchymal-matrix_fibroblast_2_cell-D231\|Adult / Lineage, Cell type, age group and donor	CYP1B1 CFD AEBP1 ZNF521 PODN	4.78e-05	185	95	5	fb6bd7e849ecf4ed9cd9c4e2a946a2d12d62f804
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	TRIM2 SLC4A7 MALRD1 ANK2 NOS1AP	4.78e-05	185	95	5	898a093757f86be3e18d2ef1f16a71f50ef81dc3
ToppCell	BALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Myeloid-Macrophage-macrophage,_alveolar-Macro_c5-WDR74\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	CYP1B1 CFD MAP4K3 CBFA2T3 NLRP3	4.78e-05	185	95	5	68edb1bb03ed221d49e583123ca4de14252d7bc5
ToppCell	PBMC-Severe-Lymphocyte-B-B_cell-B_intermediate-B_intermediate-10\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	BLK SOX5 ANK2 ZNF608 SWAP70	4.91e-05	186	95	5	d7d884ff4184636081c350d29f797bd923c6a3b4
ToppCell	PBMC-Mild-Lymphocyte-B-B_cell-B_naive-B_naive-8\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	BLK SOX5 ZNF608 SWAP70 AEBP1	5.03e-05	187	95	5	c10d6a774b3e83f64e47b9ad08f5d6b0dc60d163
ToppCell	droplet-Lung-1m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l17\|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CYP1B1 CFD AEBP1 PODN FAM171B	5.03e-05	187	95	5	ed7ab4cf4629d96dad5c74d536fc428d0a8d4eb9
ToppCell	10x5'-GI_small-bowel-Lymphocytic_T_CD4-T_CD4/CD8\|GI_small-bowel / Manually curated celltypes from each tissue	SMG1 RANBP2 BRAF SYNE2 ZNF407	5.16e-05	188	95	5	ab9b725d6e0cdab8e9ddda6dee09e14730e9a578
ToppCell	Control-Fibroblasts-Adventitial_FB\|Control / group, cell type (main and fine annotations)	CFD ANK2 AEBP1 ZNF521 PODN	5.16e-05	188	95	5	706a26c372add839d947749f0521a0e1f5c9b0ec
ToppCell	IPF-Epithelial-Club\|IPF / Disease state, Lineage and Cell class	SOX5 TRIM2 ZNF608 TACC2 NOS1AP	5.29e-05	189	95	5	f3fcef008ef252b29ac6d567fef27f9acf9cd70f
ToppCell	PBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_B-B_cell-B_c04-SOX5-TNFRSF1B\|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)	BLK SOX5 SWAP70 MAP4K3 CBFA2T3	5.43e-05	190	95	5	ed100e271aac82806f59e0c613ccda63f59100c1
ToppCell	Adult-Mesenchymal-matrix_fibroblast_2_cell-D175\|Adult / Lineage, Cell type, age group and donor	ANK2 AEBP1 ZNF521 PODN CPEB1	5.43e-05	190	95	5	7dcca3469f3a3b70db0420cb94f7765f39492f06
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Inner_Medullary_Collecting_Duct_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	SOX5 SLC4A7 RALBP1 TACC2 NOS1AP	5.56e-05	191	95	5	3e828cffa24ded19f591a7ed6c1fe88ad57fdcac
ToppCell	3'-Distal_airway-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-Adventitial_fibroblasts_L.2.1.0.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CYP1B1 CFD ANK2 AEBP1 PODN	5.56e-05	191	95	5	f5ce33af56178333730be308253943c54a0724cf
ToppCell	IPF-Epithelial-Club\|World / Disease state, Lineage and Cell class	SOX5 TRIM2 ZNF608 TACC2 NOS1AP	5.56e-05	191	95	5	3c88a6f1d74bb3b9173cd0ea3a63c6d9570e3954
ToppCell	COVID-19_Severe-B_intermediate\|World / disease group, cell group and cell class	BLK SOX5 ANK2 ZNF608 SWAP70	5.56e-05	191	95	5	f226fd69a26124ba98e4544f550b89a08e6a3708
ToppCell	3'-Distal_airway-Mesenchymal-Fibroblastic-fibroblastic_type_1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CYP1B1 CFD ANK2 AEBP1 PODN	5.70e-05	192	95	5	a8b7c539dc3037071bf068f372e4215563e11de4
ToppCell	droplet-Lung-1m-Mesenchymal-fibroblast-adventitial_fibroblast\|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CYP1B1 AEBP1 PODN FAM171B CPEB1	5.70e-05	192	95	5	f9fb24457999dc9e751a099d7f995543b9330ad4
ToppCell	Adult-Mesenchymal-matrix_fibroblast_2_cell\|Adult / Lineage, Cell type, age group and donor	ANK2 AEBP1 ZNF521 PODN CPEB1	5.70e-05	192	95	5	d21f0f577156f17c899b08871046a26b88aea011
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Medullary_Thick_Ascending_Limb_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	CYP1B1 TRIM2 SLC4A7 ANK2 SYNE2	5.70e-05	192	95	5	ee27d27e3d269764dbe8711d0b37ff9331a298a9
ToppCell	3'-Distal_airway-Mesenchymal-Fibroblastic\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CYP1B1 CFD ANK2 AEBP1 PODN	5.70e-05	192	95	5	2143e1fad2e88b90d668e12af37b2092d379090f
ToppCell	3'-Distal_airway-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CYP1B1 CFD ANK2 AEBP1 PODN	5.70e-05	192	95	5	904c003c4f73b1dfc8243cee02aad2676c515e50
ToppCell	severe-low-quality_cells\|severe / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	SMG1 SLC4A7 SYNE2 KCNJ13 USP9Y	5.84e-05	193	95	5	9337bc93e3904c7fc7c93c328518bcd6453b1e8c
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22-Lymphocytic-Lymphocytic_B-B_cell\|Severe-critical_progression_d12-22 / Compartment, severity and other cell annotations on 10x 3' data (130k)	BLK SOX5 SWAP70 PRAP1 CBFA2T3	5.99e-05	194	95	5	87604c93d20f9171e0a1279bdb6ad73fe5fed356
ToppCell	PBMC-Control-Lymphocyte-B-B_cell-B_naive-B_naive-8\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	BLK SOX5 ZNF608 SWAP70 AEBP1	5.99e-05	194	95	5	e9c907b8ec4329946338cca5ce8e954fa2cec37b
ToppCell	IPF-Multiplet-Multiplet\|IPF / Disease state, Lineage and Cell class	SOX5 TRIM2 LRRIQ1 SYNE2 TACC2	6.14e-05	195	95	5	fce0c29574bb7aab181b9c00feb42681e285d1f2
ToppCell	IPF-Multiplet\|IPF / Disease state, Lineage and Cell class	SOX5 TRIM2 LRRIQ1 SYNE2 TACC2	6.14e-05	195	95	5	eacc0449ae6f3ad8002268cd061467684c6fb9a7
ToppCell	severe-B_cell\|severe / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	BLK ZNF608 SWAP70 KCNJ13 FREM3	6.14e-05	195	95	5	0fc3c605609c9e6bdea15d73c45def2188ae5fb1
ToppCell	Bronchial-NucSeq\|Bronchial / Cell types per location group and 10X technology with lineage, and cell group designations	SOX5 BRAF MAP4K3 WDR70 ZNF407	6.29e-05	196	95	5	ab53c742866945545a92e2e61850d63c80d9a2a6
ToppCell	COVID-19-Epithelial\|COVID-19 / Condition, Lineage and Cell class	TRIM2 LRRIQ1 CIBAR2 TACC2 MAP3K19	6.44e-05	197	95	5	18fd7344628a87d5c7ef5efb66e260a4136245bf
ToppCell	Parenchymal-NucSeq\|Parenchymal / Cell types per location group and 10X technology with lineage, and cell group designations	SOX5 BRAF MAP4K3 ZNF407 WDFY3	6.60e-05	198	95	5	1996373bdccc55aac347d349bd22f6aad6d0c668
ToppCell	IPF-Endothelial-VE_Peribronchial\|Endothelial / Disease state, Lineage and Cell class	SLC4A7 SWAP70 SYNE2 TACC2 DENND5A	6.60e-05	198	95	5	b8bd1ba268480f54451648e01631b615a3401144
ToppCell	Parenchymal-NucSeq-Epithelial-Epi_airway_secretory-Secretory_Club\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	CDH26 TRIM2 ZNF608 SYNE2 NOS1AP	6.60e-05	198	95	5	1408e02e053ad3406229bfe8189da03be6366e81
ToppCell	BAL-Mild-Epithelial-Epithelial\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	TRIM2 LRRIQ1 CIBAR2 TACC2 MAP3K19	6.75e-05	199	95	5	1ee4010d8557564e25e8ee00b914c2dfd9037838
ToppCell	BAL-Mild-Epithelial-Epithelial\|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)	TRIM2 LRRIQ1 CIBAR2 TACC2 MAP3K19	6.75e-05	199	95	5	1df69c0cb5f759f6a2152521842506a75bb95cae
ToppCell	Mild-Epithelial-Epithelial-\|Mild / Condition, Lineage, Cell class and cell subclass	TRIM2 LRRIQ1 CIBAR2 TACC2 MAP3K19	6.75e-05	199	95	5	81115bbd2c10bfdd38376d2075f03a59c31870d2
ToppCell	(5)_Fibroblast-A_(Fibroblast_progenitors)\|World / Lung cell shreds - cell class (v4) and cell subclass (v4)	CYP1B1 CFD ANK2 AEBP1 PODN	6.75e-05	199	95	5	b783917fe0a9725a680aa430a42f02ce294900ef
ToppCell	BAL-Mild-Epithelial\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	TRIM2 LRRIQ1 CIBAR2 TACC2 MAP3K19	6.75e-05	199	95	5	74087b4b5e567310fc4ac58fb267ff651a180680
ToppCell	343B-Fibroblasts-Fibroblast-F\|343B / Donor, Lineage, Cell class and subclass (all cells)	CYP1B1 CFD ANK2 AEBP1 PODN	6.75e-05	199	95	5	b877c1d24357249781032e99d4237f72789cc9b8
ToppCell	BAL-Mild-Epithelial\|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)	TRIM2 LRRIQ1 CIBAR2 TACC2 MAP3K19	6.75e-05	199	95	5	00b5ce099c50a5e1786ce2b3a06ee0931a8205a4
ToppCell	Mild-Epithelial\|Mild / Condition, Lineage, Cell class and cell subclass	TRIM2 LRRIQ1 CIBAR2 TACC2 MAP3K19	6.75e-05	199	95	5	ec5fff80e2a8a94fbaf1fdcc6d45c8d7c6252e18
ToppCell	Tracheal-NucSeq\|Tracheal / Cell types per location group and 10X technology with lineage, and cell group designations	SOX5 MAP4K3 WDR70 ZNF407 WDFY3	6.75e-05	199	95	5	94b94b17ca18b8dc27b91da1f2ccf89e03cc7035
ToppCell	Mild-Epithelial-Epithelial\|Mild / Condition, Lineage, Cell class and cell subclass	TRIM2 LRRIQ1 CIBAR2 TACC2 MAP3K19	6.75e-05	199	95	5	91308b255783ad4029e5575028c18d7550832c51
ToppCell	343B-Fibroblasts-Fibroblast-F-\|343B / Donor, Lineage, Cell class and subclass (all cells)	CYP1B1 CFD ANK2 AEBP1 PODN	6.75e-05	199	95	5	e32fa66f3361474088ba1dd58574822537950d59
ToppCell	Mild_COVID-19-Epithelial\|Mild_COVID-19 / Disease group,lineage and cell class （2021.01.30）	TRIM2 LRRIQ1 CIBAR2 TACC2 MAP3K19	6.75e-05	199	95	5	72689bda7476930887ae007682fcab27f956f050
ToppCell	Lung_Parenchyma-Severe-Mesenchymal-Mesenchymal-Fibroblasts-2,_SCARA5-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	CYP1B1 CFD ANK2 AEBP1 PODN	6.92e-05	200	95	5	0b2614b8513693dd508c9003699049efd9abac52
ToppCell	cellseq-Mesenchymal-Fibroblastic-Fibroblastic_1-AF2\|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	CYP1B1 CFD ANK2 AEBP1 PODN	6.92e-05	200	95	5	28e5354008adf97b17333f17f8cbef930db6729a
ToppCell	Lung_Parenchyma-Severe-Mesenchymal-Mesenchymal-Fibroblasts-1\|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)	CYP1B1 CFD ANK2 AEBP1 PODN	6.92e-05	200	95	5	c3d4ce70ab51d74c9fe2f5864e52a4a9d7570e10
ToppCell	Tracheal-NucSeq-Stromal-Fibroblastic-Fibro_perichondrial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	CYP1B1 ANK2 AEBP1 ZNF521 PODN	6.92e-05	200	95	5	a4ec0e80f5422b91b85264a9bb74568dd577e285
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-6m-Mesenchymal-BMP_responsible_cell\|6m / Sample Type, Dataset, Time_group, and Cell type.	CYP1B1 LRRIQ1 SYNE2 KCNJ13 MAP3K19	6.92e-05	200	95	5	5fb90118d3abc28d72bc483e68317255090a04c7
ToppCell	Lung_Parenchyma-Severe-Mesenchymal-Mesenchymal-Fibroblasts-1-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	CYP1B1 CFD ANK2 AEBP1 PODN	6.92e-05	200	95	5	137f8f9d255c66336d4f8b44b2e3f3de721f2bf0
ToppCell	3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-Adventitial_fibroblasts_L.2.1.0.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CYP1B1 CFD ANK2 AEBP1 PODN	6.92e-05	200	95	5	14f3fe19b6647b32a5e28d717235741997d8522c
ToppCell	Lung_Parenchyma-Severe-Mesenchymal-Mesenchymal-Fibroblasts-2,_SCARA5\|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)	CYP1B1 CFD ANK2 AEBP1 PODN	6.92e-05	200	95	5	8d2ceb2080c67b20f452eeca605aa27a58033c04
ToppCell	Tracheal-NucSeq-Stromal-Fibroblastic\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	CFD ANK2 AEBP1 ZNF521 PODN	6.92e-05	200	95	5	b4ccffdd79526c85e5273d27b668dbddcddba1ee
ToppCell	Tracheal-NucSeq-Stromal\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	CFD ANK2 AEBP1 ZNF521 PODN	6.92e-05	200	95	5	c318d14bd6fd6f42c597eb55ac9e2f48008aeb9b
ToppCell	Tracheal-10x5prime-Stromal-Fibroblastic-Fibro_adventitial\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	CYP1B1 CFD ANK2 AEBP1 PODN	6.92e-05	200	95	5	74ad0ae592252060ee294d7483327d765a6ba1dd
ToppCell	Parenchyma_COVID-19-Stromal-TX-Fibroblasts-1\|Parenchyma_COVID-19 / Sample group, Lineage and Cell type	CYP1B1 CFD ANK2 AEBP1 PODN	6.92e-05	200	95	5	25d3865aa2ced11a5ed40013e83b47d942fdf582
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-6m-Mesenchymal-Cilia-bearing_cell\|6m / Sample Type, Dataset, Time_group, and Cell type.	LRRIQ1 KCNJ13 SLC4A10 CIBAR2 MAP3K19	6.92e-05	200	95	5	177f9ad8dd8635394c575a2b30140184df0bd51e
ToppCell	Tracheal-10x5prime-Stromal-Fibroblastic\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	CYP1B1 CFD ANK2 AEBP1 PODN	6.92e-05	200	95	5	7ba292c30d915e66ebc8026fa76492cedf64700e
ToppCell	Parenchymal-NucSeq-Stromal-Fibroblastic-Fibro_adventitial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	CFD ANK2 AEBP1 ZNF521 PODN	6.92e-05	200	95	5	74e74123ea7bf38d337a3a0248a6a51437c6ab42
ToppCell	Parenchyma_COVID-19-Stromal-TX-Fibroblasts-2,_SCARA5\|Parenchyma_COVID-19 / Sample group, Lineage and Cell type	CYP1B1 CFD ANK2 AEBP1 PODN	6.92e-05	200	95	5	c338a08c1605527ab9aaf62ea151a19e8469dc6d
ToppCell	Tracheal-10x5prime-Stromal\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	CYP1B1 CFD ANK2 AEBP1 PODN	6.92e-05	200	95	5	920e6036c0a9c0089d0d898673daf9dd9d7279fc
ToppCell	Tracheal-NucSeq-Stromal-Fibroblastic-Fibro_adventitial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	CYP1B1 CFD ANK2 AEBP1 PODN	6.92e-05	200	95	5	0c25d56292b9e5fefa4521b72635449be1ffd6fe
ToppCell	cellseq-Mesenchymal-Fibroblastic-Fibroblastic_1\|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	CYP1B1 CFD ANK2 AEBP1 PODN	6.92e-05	200	95	5	56536236a7012efdb28f85b40e464f3da3e87ce8
ToppCell	Bronchial-10x5prime-Stromal-Schwann-Schwann_nonmyelinating\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	ANK2 TTLL11 PODN ARHGEF17	1.11e-04	116	95	4	b0a3c109c5f20ab699e53bf8ab3903d102f5f315
ToppCell	VE-CD4-CD4_Treg\|VE / Condition, Cell_class and T cell subcluster	SYNE2 TACC2 FAM171B MYO18B	1.68e-04	129	95	4	e89d414e1b23e1656747defa39f09b51944a2166
ToppCell	PBMC-Severe-Lymphocyte-B-B_cell-B_intermediate-B_activate-7\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	BLK SOX5 ZNF608 SWAP70	1.83e-04	132	95	4	c07842a4b514f1e950c8af303f3b6b4275906e6a
ToppCell	BALF-PFMC-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c02-GPR183\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	PTTG1 SLC4A7 ZDBF2 DARS2	2.30e-04	140	95	4	7b359bfbd404ab06d799048252f4985d85852048
ToppCell	Posterior_cortex-Neuronal-Excitatory-eN1(Slc17a7)-eN1_1-Calb1-Excitatory_Neuron.Sc17a7.Calb1-Fos_(Layer_2/3,_IEG+)\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	MALRD1 MIA2 YIPF7	2.33e-04	56	95	3	a6a0345ddb9db1441fc048bc4d7b05f625de2ccd
ToppCell	Posterior_cortex-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)-Syt6-Excitatory_Neuron.Slc17a7.Syt6-Tshz2-Nrep_(Subiculum_and_Entorhinal_Cortex)\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	PRAP1 YIPF7 PSMB11	2.33e-04	56	95	3	7b7aaa514a3e85250d6279e0770a9409c4b0b199
ToppCell	Posterior_cortex-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)-Syt6-Excitatory_Neuron.Slc17a7.Syt6-Tshz2-Nrep_(Subiculum_and_Entorhinal_Cortex)-\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	PRAP1 YIPF7 PSMB11	2.33e-04	56	95	3	17c37bdd1f9733c3823e98ed4d1cd0ca9db66e9c
ToppCell	3'_v3-bone_marrow-Hematopoietic_progenitors-Progenitor\|bone_marrow / Manually curated celltypes from each tissue	KIF26A ZNF521 CBFA2T3 ARHGEF17	2.91e-04	149	95	4	078e1e5765e476ba85c23fb8f6892b6698cbcbdb
ToppCell	Influenza_Severe-CD4+_T_naive\|World / Disease group and Cell class	ANKRD31 FAM153B FAM153A TRIM2	2.91e-04	149	95	4	ce6552063510aa3e0b9d6e5b531eea67410e7056
ToppCell	PBMC-Mild-Lymphocyte-B-B_cell-B_intermediate-B_intermediate-10\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	BLK SOX5 ANK2 SWAP70	3.46e-04	156	95	4	d81e78bec5c8a3f3ec9e1447ebab2c5805b815eb
Disease	age at first sexual intercourse measurement	BLK SOX5 PHF2 TTLL11 ZNF521 CPEB1 WDR24	1.51e-04	383	88	7	EFO_0009749
Disease	tumor necrosis factor receptor superfamily member 19L measurement	CFD ARHGEF17	2.43e-04	8	88	2	EFO_0008309
Disease	frontal fibrosing alopecia	CYP1B1 TTLL11 BANP	4.02e-04	48	88	3	EFO_0009855
Disease	T wave morphology measurement	SOX5 NOS1AP	7.82e-04	14	88	2	EFO_0008398
Disease	Asbestosis	CFD NLRP3	7.82e-04	14	88	2	C0003949
Disease	Pulmonary Fibrosis - from Asbestos Exposure	CFD NLRP3	7.82e-04	14	88	2	C2930617
Disease	anemia (implicated_via_orthology)	SLC4A7 SLC4A10	9.00e-04	15	88	2	DOID:2355 (implicated_via_orthology)
Disease	Romano-Ward Syndrome	ANK2 NOS1AP	1.03e-03	16	88	2	C0035828
Disease	Adenocarcinoma of prostate	BRAF AXIN1	1.61e-03	20	88	2	C0007112
Disease	platelet crit	ANKRD31 SLC4A7 SWAP70 KIF26A BANP ZNF407 POLR1B NLRP3 WDR24	2.14e-03	952	88	9	EFO_0007985
Disease	Depressive Symptoms	CYP1B1 FASN	2.73e-03	26	88	2	C0086132
Disease	Neurodevelopmental Disorders	PHF2 ANK2 WDFY3	2.74e-03	93	88	3	C1535926
Disease	Ischemic stroke	SOX5 DCHS2 ANK2 SWAP70 CEP164	2.88e-03	324	88	5	HP_0002140

Protein segments in the cluster

Peptide	Gene	Start	Entry
EDLSPDHPVVLENHV	BANP	16	Q8N9N5
EHHPIPQEEASLAET	BRAF	296	P15056
LFLHDVDLLPENDHN	B4GALT3	191	O60512
VQLSRANEDPEHPHA	CIBAR2	256	Q6ZTR7
EETHVEAREHQPEPE	AEBP1	211	Q8IUX7
HLHFDQGPLVEPAAD	CCDC87	506	Q9NVE4
ALEADTFPDEIHHPK	DMTF1	606	Q9Y222
DHQDAIAPEHNDPIH	IQGAP1	1311	P46940
IAPEHNDPIHELLDD	IQGAP1	1316	P46940
SEHPHDEEEEALNIP	NBPF4	246	Q96M43
HDILHEPPDVVSDDE	RALBP1	51	Q15311
HNEDIHFEPIVSLPE	RANBP2	2906	P49792
HEQDIRAEQPVEPHD	RAB44	451	Q7Z6P3
PELLVFPAQTDLHEH	NSUN5	186	Q96P11
DEIFDQIPELLEHHE	ARHGEF17	1111	Q96PE2
LIERIPDENGHDHAE	ANK2	3546	Q01484
VPHPDSQPDTIDHDL	CFD	101	P00746
QQHIPETHNDLPEEL	ANKRD31	766	Q8N7Z5
DLREFPGDLPEHTNH	PODN	86	Q7Z5L7
TEPHHELPDSDGFLD	MAP4K3	346	Q8IVH8
EDVDLHLFLPDCHPS	KIAA1109	586	Q2LD37
PISSHPFHIEDEVDD	MAPK6	326	Q16659
DEHQHVPEDPREKSQ	CWF19L2	441	Q2TBE0
PSEDHLEEFIAEHLP	FAM153A	76	Q9UHL3
ELDHDAPPENHTICV	KCNJ13	86	O60928
LQELATHLHPAEPEE	LRATD2	266	Q96KN1
HLLQAPASHEDLDAP	KIF26A	141	Q9ULI4
LLHLRHPEAEDPSAE	GNL1	456	P36915
LLEPEPEEDASHAHP	PSMB11	251	A5LHX3
ENGSDRDPLHPEHLS	CBFA2T3	301	O75081
APDHQDPLHELLEDL	IQGAP3	1301	Q86VI3
HDLPMDEHVLPDDAD	LRRIQ1	141	Q96JM4
DSDDSPLLDDFHVHP	DCHS2	106	Q6V1P9
DDNDDGHPLHPSLNI	PRR27	26	Q6MZM9
VGQAEHLEEEHDPSP	GOLIM4	351	O00461
ELSADFEHQAPPRDH	MALRD1	681	Q5VYJ5
EELHLLHFPNSPEEN	FER1L6-AS2	51	Q96M78
EDPLEDPHLHLNIEE	C6orf52	101	Q5T4I8
EELHEAVKHIAEDPP	GAS2L3	211	Q86XJ1
PPDEHLDEDKHFVVA	BLK	51	P51451
DAHEENPESILDEHV	AXIN1	461	O15169
DLLQDTSHLPPEHSD	FOXRED1	51	Q96CU9
DIDNHFIELPEDLPQ	DENND5A	386	Q6IQ26
HAVDVVLDPDTAHPD	BTN2A1	326	Q7KYR7
NPHAEAHEAIFDLDL	ITIH6	61	Q6UXX5
DGDPHFVIQIPHSEE	ITIH6	1081	Q6UXX5
ESAVHEPLHIEAEDP	CDH26	511	Q8IXH8
HAPEDPSDLLQHVKF	IL22RA1	16	Q8N6P7
AHELPLDAHVLEPDE	CACTIN	566	Q8WUQ7
RGIHDHLPDFQDSEE	CPEB1	56	Q9BZB8
HDDPEFRELLSHNEE	CYP1B1	216	Q16678
DDGHDLRIPLHNEDA	NOS1AP	11	O75052
HFLLEEDKPEEPTAH	FASN	1516	P49327
IHSHAQPPDAREEDI	FAM171B	591	Q6P995
EELHHQIPFIPSEDS	MAP3K19	841	Q56UN5
DHLEEFIAEHLPEAS	FAM153B	156	P0C7A2
EDTLGHVLSPEPDHD	PRAP1	96	Q96NZ9
ESFDLPEEHQIAHLP	PTTG1	126	O95997
HEHPLTSELDPEKEQ	MIA2	411	Q96PC5
ELLFDPDDEHSEPVH	NLRP3	206	Q96P20
QLAFHVQDDHDPPNL	FREM3	671	P0C091
VCTPEAHEPDKEDNH	SKOR1	796	P84550
EENPRELESAHHPFT	DARS2	491	Q6PI48
FILGTEDDDEEHIPH	SLC4A7	96	Q9Y6M7
LNFDDPLNIEAAEHH	UBE2F	151	Q969M7
AEHEDELPEHFKPSQ	PHF2	416	O75151
DCDINDDEFLHLPAH	TIMM29	181	Q9BSF4
AQSEDPLPELHEDLH	SYNE2	5831	Q8WXH0
PLPELHEDLHNEKEL	SYNE2	5836	Q8WXH0
SEHPHDEEEEALNIP	NBPF5P	246	Q86XG9
SEHPHDEEEEALNIP	NBPF6	246	Q5VWK0
QIPLDEDDPRLHLSH	SMG1	1761	Q96Q15
ESFDLPEEHQIAHLP	PTTG3P	126	Q9NZH4
TIDAIPDHHPGEEIF	SLF2	731	Q8IX21
HLSDLAPLLLHPEEE	INTS5	606	Q6P9B9
NNASPHFEPDLHIED	CEP164	1051	Q9UPV0
EHEHELSPGVFENVP	TTLL11	541	Q8NHH1
ALADEDHSLHPPLQR	WDFY3	911	Q8IZQ1
KQHQDSRLEPEPHEE	PHLPP2	1296	Q6ZVD8
EEEENPVHKIPDSHE	WDR70	161	Q9NW82
DFPEDLQKHIAECHP	ZNF521	256	Q96K83
FILGTEDDDEEHIPH	SLC4A10	101	Q6U841
LPEHHEAFNRLLEDP	SPDYE1	151	Q8NFV5
HRELLHPSPNQDSEE	ZNF646	26	O15015
PVEAEAAPHTDQDHV	ZNF646	541	O15015
FDSDIPLHSGNDHPE	ZDBF2	831	Q9HCK1
PELEEELEADHTPHY	TNFRSF8	546	P28908
DETHDPKLQHLAPEE	TACC2	1801	O95359
HEDEEPAFPHTELAN	USP9Y	61	O00507
EVDEEHVHRANPPEL	MYO18B	556	Q8IUG5
HVHRANPPELDQVED	MYO18B	561	Q8IUG5
HDDPLEPHQGNQEKL	ZIM2	251	Q9NZV7
HAHLDPENKLEFEPD	ZNF608	576	Q9ULD9
EEESDGLPAFHLPLH	SOX5	41	P35711
PHDPVALEEHFRDDD	SWAP70	46	Q9UH65
HLKEQHPDIENPDLA	ZNF407	1791	Q9C0G0
EEPPLLEELGIHFDH	YIPF7	111	Q8N8F6
EEDELYLLDPEHAHP	WDR24	546	Q96S15
DQDFPLHPRENDQLD	TRIM2	286	Q9C040
LPPQALIEHHEEAEE	POLR1B	151	Q9H9Y6
LEHIQQHPEEPLEGT	TMEM251	71	Q8N6I4
DEIHSPAHPEIEKAD	ZNF649	71	Q9BS31