Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyBiologicalProcessnuclear-transcribed mRNA poly(A) tail shortening

CPEB3 TNRC6C TNRC6A TNKS1BP1

1.56e-0533954GO:0000289
GeneOntologyBiologicalProcesspositive regulation of nuclear-transcribed mRNA poly(A) tail shortening

CPEB3 TNRC6C TNRC6A

3.32e-0514953GO:0060213
GeneOntologyBiologicalProcessregulation of nuclear-transcribed mRNA poly(A) tail shortening

CPEB3 TNRC6C TNRC6A

5.08e-0516953GO:0060211
DomainNECAP_PHear

NECAP1 NECAP2

2.40e-052922IPR012466
DomainM_domain

TNRC6C TNRC6A

2.40e-052922PF12938
DomainGW182_M_dom

TNRC6C TNRC6A

2.40e-052922IPR026805
DomainDUF1681

NECAP1 NECAP2

2.40e-052922PF07933
DomainFN3

SPEG IFNLR1 PTPRF PTPRS ROBO2 ROS1 USH2A

5.72e-05199927PS50853
DomainAgo_hook

TNRC6C TNRC6A

7.18e-053922PF10427
DomainTNRC6_PABC-bd

TNRC6C TNRC6A

7.18e-053922IPR032226
DomainDapper

DACT1 DACT3

7.18e-053922IPR024843
DomainArgonaute_hook_dom

TNRC6C TNRC6A

7.18e-053922IPR019486
DomainTNRC6-PABC_bdg

TNRC6C TNRC6A

7.18e-053922PF16608
DomainDapper

DACT1 DACT3

7.18e-053922PF15268
DomainFN3_dom

SPEG IFNLR1 PTPRF PTPRS ROBO2 ROS1 USH2A

7.79e-05209927IPR003961
DomainWWE

DTX4 DTX2

1.43e-044922SM00678
DomainWWE-dom_subgr

DTX4 DTX2

1.43e-044922IPR018123
Domainfn3

SPEG PTPRF PTPRS ROBO2 ROS1 USH2A

1.50e-04162926PF00041
DomainFN3

SPEG PTPRF PTPRS ROBO2 ROS1 USH2A

3.07e-04185926SM00060
Domain-

SYNE1 LMO7 NAV2 CAMSAP2

4.16e-04719241.10.418.10
DomainCH

SYNE1 LMO7 NAV2 CAMSAP2

4.63e-0473924PS50021
DomainCH-domain

SYNE1 LMO7 NAV2 CAMSAP2

5.13e-0475924IPR001715
DomainPDZ

PCLO FRMPD2 MAST2 LMO7 GRIP2

9.03e-04151925PS50106
DomainPDZ

PCLO FRMPD2 MAST2 LMO7 GRIP2

9.31e-04152925IPR001478
DomainWWE

DTX4 DTX2

1.53e-0312922PS50918
DomainWWE

DTX4 DTX2

1.53e-0312922PF02825
DomainWWE-dom

DTX4 DTX2

1.53e-0312922IPR004170
DomainVWD

MUC19 SUSD2

2.75e-0316922SM00216
DomainVWF_type-D

MUC19 SUSD2

2.75e-0316922IPR001846
DomainVWFD

MUC19 SUSD2

2.75e-0316922PS51233
DomainVWD

MUC19 SUSD2

2.75e-0316922PF00094
DomainUBA-like

TNRC6C UBAP2L TNRC6A

3.88e-0364923IPR009060
DomainCH

SYNE1 LMO7 NAV2

4.05e-0365923SM00033
DomainCH

SYNE1 LMO7 NAV2

4.99e-0370923PF00307
DomainPDZ

FRMPD2 MAST2 LMO7 GRIP2

5.21e-03141924PF00595
Domain-

SPEG MXRA8 PTGFRN IFNLR1 PTPRF PTPRS ROBO2 ROS1 USH2A

5.36e-036639292.60.40.10
DomainIGv

MXRA8 PTGFRN ROBO2

6.05e-0375923SM00406
DomainPDZ

FRMPD2 MAST2 LMO7 GRIP2

6.17e-03148924SM00228
Domain-

FRMPD2 MAST2 LMO7 GRIP2

6.47e-031509242.30.42.10
DomainIg-like_fold

SPEG MXRA8 PTGFRN IFNLR1 PTPRF PTPRS ROBO2 ROS1 USH2A

7.97e-03706929IPR013783
DomainUBA

TNRC6C UBAP2L

9.55e-0330922SM00165
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

SPEG RTTN TNRC6C MAST2 IFNLR1 DACT1 PTPRF SETD5 PTPRS USP40 NAV2 NAV1 NLE1 RIPOR1 TNKS1BP1 DTX2 ATG9A HECTD1 MED13

1.99e-101105971935748872
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

SYNE1 KIAA0232 SPEG TNRC6C SETD5 UBAP2L SPHKAP DENND4B NAV1 RIPOR1 CAMSAP2

1.99e-08407971112693553
Pubmed

Targeting TRIM37-driven centrosome dysfunction in 17q23-amplified breast cancer.

GIGYF1 JMJD1C CEP170 ARHGAP22 KRBA1 TNRC6A NAV1 CAMSAP2

5.10e-0818497832908313
Pubmed

Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.

SYNE1 KIAA0232 TOGARAM1 TNRC6C LMO7 NAV2 TNKS1BP1 GRIP2

2.39e-0722597812168954
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

VANGL2 UBE2O LMO7 TNRC6A NAV2 TMEM131L ROBO2 TNKS1BP1 EIF2AK4 MED13 ZNF646

2.78e-07529971114621295
Pubmed

Prediction of the coding sequences of unidentified human genes. XIX. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.

SYNE1 UBE2O SETD5 SPHKAP TNKS1BP1 GRIP2

4.37e-0710297611214970
Pubmed

An antibody-based proximity labeling map reveals mechanisms of SARS-CoV-2 inhibition of antiviral immunity.

PIK3AP1 MXRA8 KANK2 JMJD1C CEP170 UBE2O NECAP2 MAVS TNRC6A NAV1 TMEM131L HECTD1

9.76e-07733971234672954
Pubmed

A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration.

ZSWIM8 GIGYF1 XRCC4 KIAA1549L UBAP2L TMPO ROBO2 GCC1 GRIP2 DTX2 CAMSAP2

1.09e-06608971116713569
Pubmed

All Dact (Dapper/Frodo) scaffold proteins dimerize and exhibit conserved interactions with Vangl, Dvl, and serine/threonine kinases.

VANGL2 DACT1 DACT3

1.17e-06897321718540
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

SEC16B RAP1GAP TOGARAM1 PTGFRN JMJD1C CEP170 KRBA1 DTX2 SPIDR HECTD1

1.25e-06493971015368895
Pubmed

14-3-3 proteins sequester a pool of soluble TRIM32 ubiquitin ligase to repress autoubiquitylation and cytoplasmic body formation.

SPEG GIGYF1 CEP170 HECTD1

5.87e-064297423444366
Pubmed

SR protein kinases promote splicing of nonconsensus introns.

SEC16B TOGARAM1 MAST2 KANK2 JMJD1C CEP170 LMO7 TMPO

8.07e-0636197826167880
Pubmed

TRIM65 regulates microRNA activity by ubiquitination of TNRC6.

TNRC6C KANK2 CEP170 UBE2O TNRC6A TNKS1BP1 HECTD1 GPRASP2

8.57e-0636497824778252
Pubmed

Prediction of the coding sequences of unidentified human genes. XV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.

SYNE1 VANGL2 MAVS NAV1 GRIP2

1.07e-0510397510574462
Pubmed

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.

DCAF6 KIAA0232 FRMPD2 TNRC6C JMJD1C CEP170 SETD5 UBAP2L PTPRS USP40 NAV1 RIPOR1 EIF2AK4 SPIDR HECTD1

1.58e-051489971528611215
Pubmed

Human GW182 Paralogs Are the Central Organizers for RNA-Mediated Control of Transcription.

TNRC6A TNKS1BP1 EIF2AK4 MED13

2.30e-055997428813667
Pubmed

SEC14 and spectrin domains 1 (Sestd1) and Dapper antagonist of catenin 1 (Dact1) scaffold proteins cooperatively regulate the Van Gogh-like 2 (Vangl2) four-pass transmembrane protein and planar cell polarity (PCP) pathway during embryonic development in mice.

VANGL2 DACT1

2.31e-05397223696638
Pubmed

LAR receptor phospho-tyrosine phosphatases regulate NMDA-receptor responses.

PTPRF PTPRS

2.31e-05397231985401
Pubmed

Trans-synaptic adhesions between netrin-G ligand-3 (NGL-3) and receptor tyrosine phosphatases LAR, protein-tyrosine phosphatase delta (PTPdelta), and PTPsigma via specific domains regulate excitatory synapse formation.

PTPRF PTPRS

2.31e-05397220139422
Pubmed

Developmental expression of the cell adhesion molecule-like protein tyrosine phosphatases LAR, RPTPdelta and RPTPsigma in the mouse.

PTPRF PTPRS

2.31e-0539729784606
Pubmed

Intact synapse structure and function after combined knockout of PTPδ, PTPσ, and LAR.

PTPRF PTPRS

2.31e-05397233656439
Pubmed

Neuron navigator: a human gene family with homology to unc-53, a cell guidance gene from Caenorhabditis elegans.

NAV2 NAV1

2.31e-05397212079279
Pubmed

Sensory deficits in mice hypomorphic for a mammalian homologue of unc-53.

NAV2 NAV1

2.31e-05397215158073
Pubmed

Three Dact gene family members are expressed during embryonic development and in the adult brains of mice.

DACT1 DACT3

2.31e-05397216881060
Pubmed

Impact of scaffolding protein TNRC6 paralogs on gene expression and splicing.

TNRC6C TNRC6A

2.31e-05397234108231
Pubmed

Dact1-3 mRNAs exhibit distinct expression domains during tooth development.

DACT1 DACT3

2.31e-05397220170752
Pubmed

Pore membrane and/or filament interacting like protein 1 (POMFIL1) is predominantly expressed in the nervous system and encodes different protein isoforms.

NAV2 NAV1

2.31e-05397212062803
Pubmed

DNA hypermethylation is associated with invasive phenotype of malignant melanoma.

ARHGAP22 NAV2

2.31e-05397231602702
Pubmed

Gawky is a component of cytoplasmic mRNA processing bodies required for early Drosophila development.

TNRC6C TNRC6A

2.31e-05397216880270
Pubmed

T cells develop normally in the absence of both Deltex1 and Deltex2.

DTX4 DTX2

2.31e-05397216923970
Pubmed

Expression of TNRC6 (GW182) Proteins Is Not Necessary for Gene Silencing by Fully Complementary RNA Duplexes.

TNRC6C TNRC6A

2.31e-05397231670606
Pubmed

Identification of novel rare mutations of DACT1 in human neural tube defects.

VANGL2 DACT1

2.31e-05397222610794
Pubmed

Interactomes of Glycogen Synthase Kinase-3 Isoforms.

KANK2 UBE2O TNRC6A TNKS1BP1 CAMSAP2 HECTD1

2.75e-0520997636779422
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

RAP1GAP KIAA0232 GIGYF1 MAST2 CEP170 LMO7 NAV2 NAV1 TNKS1BP1 CAMSAP2 HECTD1

2.88e-05861971136931259
Pubmed

Protein-protein interactions between large proteins: two-hybrid screening using a functionally classified library composed of long cDNAs.

MAST2 UBAP2L NAV1 HECTD1 MED13

3.30e-0513097512421765
Pubmed

KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.

RAP1GAP SYNE1 PCLO KANK2 CEP170 UBE2O LMO7 UBAP2L PTPRS FGA NAV1 TMPO TNKS1BP1 CAMSAP2

4.29e-051431971437142655
Pubmed

Dynamic changes in the expression of protein tyrosine phosphatases during preimplantation mouse development: semi-quantification by real-time PCR.

PTPRF PTPRS

4.60e-05497214967925
Pubmed

Control of hepatitis C virus replication in mouse liver-derived cells by MAVS-dependent production of type I and type III interferons.

IFNLR1 MAVS

4.60e-05497225609814
Pubmed

The interactions of GW182 proteins with PABP and deadenylases are required for both translational repression and degradation of miRNA targets.

TNRC6C TNRC6A

4.60e-05497223172285
Pubmed

Identification of a family of endocytic proteins that define a new alpha-adaptin ear-binding motif.

NECAP1 NECAP2

4.60e-05497214555962
Pubmed

Protein Tyrosine Phosphatase PTPRS Is an Inhibitory Receptor on Human and Murine Plasmacytoid Dendritic Cells.

PTPRF PTPRS

4.60e-05497226231120
Pubmed

The LAR/PTP delta/PTP sigma subfamily of transmembrane protein-tyrosine-phosphatases: multiple human LAR, PTP delta, and PTP sigma isoforms are expressed in a tissue-specific manner and associate with the LAR-interacting protein LIP.1.

PTPRF PTPRS

4.60e-0549728524829
Pubmed

Two PABPC1-binding sites in GW182 proteins promote miRNA-mediated gene silencing.

TNRC6C TNRC6A

4.60e-05497221063388
Pubmed

MDA5 Is an Essential Sensor of a Pathogen-Associated Molecular Pattern Associated with Vitality That Is Necessary for Host Resistance against Aspergillus fumigatus.

IFNLR1 MAVS

4.60e-05497233087405
Pubmed

Structural basis of binding of P-body-associated proteins GW182 and ataxin-2 by the Mlle domain of poly(A)-binding protein.

TNRC6C TNRC6A

4.60e-05497220181956
Pubmed

DELTEX2 C-terminal domain recognizes and recruits ADP-ribosylated proteins for ubiquitination.

DTX4 TMPO DTX2

6.55e-052897332937373
Pubmed

Prediction of the coding sequences of unidentified human genes. XVI. The complete sequences of 150 new cDNA clones from brain which code for large proteins in vitro.

SPEG PTGFRN JMJD1C NAV2 EIF2AK4

7.18e-0515397510718198
Pubmed

Multiple interactions between receptor protein-tyrosine phosphatase (RPTP) alpha and membrane-distal protein-tyrosine phosphatase domains of various RPTPs.

PTPRF PTPRS

7.66e-05597210777529
Pubmed

Interleukin-1 receptor accessory protein organizes neuronal synaptogenesis as a cell adhesion molecule.

PTPRF PTPRS

7.66e-05597222357843
Pubmed

The PHLPP1 N-Terminal Extension Is a Mitotic Cdk1 Substrate and Controls an Interactome Switch.

KANK2 JMJD1C CEP170 LMO7 UBAP2L TNKS1BP1

8.47e-0525697633397691
Pubmed

Expression of the immunoglobulin superfamily cell adhesion molecules in the developing spinal cord and dorsal root ganglion.

SPEG MXRA8 PTGFRN PTPRF PTPRS

9.40e-0516297525826454
Pubmed

RNF43 inhibits WNT5A-driven signaling and suppresses melanoma invasion and resistance to the targeted therapy.

GIGYF1 JMJD1C VANGL2 UBE2O TNRC6A TMEM131L

9.82e-0526397634702444
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: I. The complete nucleotide sequences of 100 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

ZSWIM8 PCLO CPEB3 MAST2

1.06e-048797412465718
Pubmed

Maturation of ureter-bladder connection in mice is controlled by LAR family receptor protein tyrosine phosphatases.

PTPRF PTPRS

1.15e-04697219273906
Pubmed

Expression of Muc19/Smgc gene products during murine sublingual gland development: cytodifferentiation and maturation of salivary mucous cells.

MUC19 MUC16

1.15e-04697219110483
Pubmed

Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation.

OTUD5 MAST2 KANK2 IFNLR1 DACT1 AP1AR DMKN PTPRS FGA RIPOR1 EIF2AK4 MED13

1.45e-041215971215146197
Pubmed

Modulation of apoptotic response by LAR family phosphatases-cIAP1 signaling during urinary tract morphogenesis.

PTPRF PTPRS

1.60e-04797229073098
Pubmed

Regulation of Wnt/PCP signaling through p97/VCP-KBTBD7-mediated Vangl ubiquitination and endoplasmic reticulum-associated degradation.

KBTBD7 VANGL2

1.60e-04797233990333
Pubmed

Identification and typing of members of the protein-tyrosine phosphatase gene family expressed in mouse brain.

PTPRF PTPRS

1.60e-0479721454056
Pubmed

Intra- and intermolecular interactions between intracellular domains of receptor protein-tyrosine phosphatases.

PTPRF PTPRS

1.60e-04797212376545
Pubmed

Functional dissection of the human TNRC6 (GW182-related) family of proteins.

TNRC6C TNRC6A

1.60e-04797219470757
Pubmed

The C-terminal domains of human TNRC6A, TNRC6B, and TNRC6C silence bound transcripts independently of Argonaute proteins.

TNRC6C TNRC6A

1.60e-04797219383768
Pubmed

A genetic screen identifies a protective type III interferon response to Cryptosporidium that requires TLR3 dependent recognition.

IFNLR1 MAVS

1.60e-04797235584177
Pubmed

Dynamic microtubules catalyze formation of navigator-TRIO complexes to regulate neurite extension.

NAV2 NAV1

1.60e-04797225065758
Pubmed

Protein interactome reveals converging molecular pathways among autism disorders.

ZSWIM8 KIAA0232 ARHGAP22 KIAA1549L UBAP2L TMPO GCC1 GRIP2

1.77e-0456097821653829
Pubmed

Prediction of the coding sequences of unidentified human genes. XIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.

CPEB3 DTX4 TMEM131L PHLPP2

1.96e-0410297410231032
Pubmed

A DDX6-CNOT1 complex and W-binding pockets in CNOT9 reveal direct links between miRNA target recognition and silencing.

TNRC6C TNRC6A

2.13e-04897224768540
Pubmed

Type I and type III interferons drive redundant amplification loops to induce a transcriptional signature in influenza-infected airway epithelia.

IFNLR1 MAVS

2.13e-04897224278020
Pubmed

Combinatorial expression of neurexins and LAR-type phosphotyrosine phosphatase receptors instructs assembly of a cerebellar circuit.

PTPRF PTPRS

2.13e-04897237591863
Pubmed

Protein Tyrosine Phosphatase δ Mediates the Sema3A-Induced Cortical Basal Dendritic Arborization through the Activation of Fyn Tyrosine Kinase.

PTPRF PTPRS

2.13e-04897228637841
Pubmed

An innate antiviral pathway acting before interferons at epithelial surfaces.

IFNLR1 MAVS

2.13e-04897226595890
Pubmed

Protein interaction network of the mammalian Hippo pathway reveals mechanisms of kinase-phosphatase interactions.

GIGYF1 MAST2 CEP170 LMO7 TNRC6A NAV1 HECTD1

2.59e-0444697724255178
Pubmed

Comparative host-coronavirus protein interaction networks reveal pan-viral disease mechanisms.

ZNRD2 TNRC6C KANK2 CEP170 LMO7 UBAP2L GCC1 HECTD1 GPRASP2

2.64e-0475497933060197
Pubmed

Definition of the consensus motif recognized by gamma-adaptin ear domains.

NECAP1 NECAP2

2.74e-04997214665628
Pubmed

The Kinase MAP4K1 Inhibits Cytosolic RNA-Induced Antiviral Signaling by Promoting Proteasomal Degradation of TBK1/IKKε.

MAVS DTX4

2.74e-04997234908452
Pubmed

Interaction between liprin-alpha and GIT1 is required for AMPA receptor targeting.

PTPRF GRIP2

2.74e-04997212629171
Pubmed

Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.

ZSWIM8 DCAF6 GIGYF1 MAST2 KANK2 VANGL2 CEP170 SETD5 TNRC6A CRNN ZNF646

2.83e-041116971131753913
Pubmed

A directed protein interaction network for investigating intracellular signal transduction.

RAP1GAP MAST2 JMJD1C KBTBD7 DACT1 TMEM44 ROBO2 RIPOR1 OSBP2 ATG9A GPRASP2

3.01e-041124971121900206
Pubmed

An organelle-specific protein landscape identifies novel diseases and molecular mechanisms.

GIGYF1 XRCC4 CEP170 BBX LMO7 SETD5 DACT3 CRNN NAV1 RIPOR1 TNKS1BP1 CAMSAP2

3.12e-041321971227173435
Pubmed

14-3-3ε and NAV2 interact to regulate neurite outgrowth and axon elongation.

JMJD1C NAV2

3.41e-041097224161943
Pubmed

miRNA-mediated deadenylation is orchestrated by GW182 through two conserved motifs that interact with CCR4-NOT.

TNRC6C TNRC6A

3.41e-041097221984185
Pubmed

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

ZNRD2 SYNE1 KANK2 CEP170 UBE2O UBAP2L PTPRS SPHKAP NAV1 CAMSAP2

3.62e-04963971028671696
Pubmed

PTPσ functions as a presynaptic receptor for the glypican-4/LRRTM4 complex and is essential for excitatory synaptic transmission.

PTPRF PTPRS

4.17e-041197225624497
Pubmed

A novel receptor-type protein tyrosine phosphatase with a single catalytic domain is specifically expressed in mouse brain.

PTPRF PTPRS

4.17e-04119727832766
Pubmed

IFN-λ derived from nonsusceptible enterocytes acts on tuft cells to limit persistent norovirus.

IFNLR1 MAVS

4.17e-041197237703370
Pubmed

Meta-analysis of genome-wide association data of bipolar disorder and major depressive disorder.

SYNE1 PCLO

4.17e-041197220351715
Pubmed

VANGL2 inhibits antiviral IFN-I signaling by targeting TBK1 for autophagic degradation.

VANGL2 MAVS

4.17e-041197237352355
Pubmed

miRNA repression involves GW182-mediated recruitment of CCR4-NOT through conserved W-containing motifs.

TNRC6C TNRC6A

4.17e-041197221984184
Pubmed

Proximity biotinylation and affinity purification are complementary approaches for the interactome mapping of chromatin-associated protein complexes.

XRCC4 KANK2 CEP170 UBE2O BBX UBAP2L NAV1 MED13

4.55e-0464597825281560
Pubmed

Impaired plasma membrane localization of ubiquitin ligase complex underlies 3-M syndrome development.

PCLO RTTN KANK2 KBTBD7 USP40 TMPO GPRASP2

4.90e-0449697731343991
Pubmed

A human skeletal muscle interactome centered on proteins involved in muscular dystrophies: LGMD interactome.

DCAF6 SYNE1 MAST2 JMJD1C CEP170 DACT1 MED13

4.95e-0449797723414517
Pubmed

FBXO22 promotes leukemogenesis by targeting BACH1 in MLL-rearranged acute myeloid leukemia.

SPEG KRBA1 LMO7 FGA NAV2 TMPO EIF2AK4

4.95e-0449797736774506
Pubmed

Nuclear membrane protein LAP2beta mediates transcriptional repression alone and together with its binding partner GCL (germ-cell-less).

TMPO MXD1

4.99e-041297211591818
Pubmed

Liprins, a family of LAR transmembrane protein-tyrosine phosphatase-interacting proteins.

PTPRF PTPRS

4.99e-04129729624153
Pubmed

The CEP19-RABL2 GTPase Complex Binds IFT-B to Initiate Intraflagellar Transport at the Ciliary Base.

CEP170 TTBK2

4.99e-041297228625565
Pubmed

Identification of 14-3-3epsilon substrates from embryonic murine brain.

GIGYF1 CEP170 LMO7 NAV1

5.23e-0413297416944949
Pubmed

Characterization of cDNA clones in size-fractionated cDNA libraries from human brain.

RAP1GAP CEP170 DENND4B

5.24e-04569739455484
Pubmed

CEMIP, acting as a scaffold protein for bridging GRAF1 and MIB1, promotes colorectal cancer metastasis via activating CDC42/MAPK pathway.

PTGFRN LMO7 TNKS1BP1

5.52e-045797336849460
Pubmed

Human Immunodeficiency Virus Type 1 Vpr Mediates Degradation of APC1, a Scaffolding Component of the Anaphase-Promoting Complex/Cyclosome.

JMJD1C CEP170 UBE2O UBAP2L TNRC6A

5.99e-0424297534011540
Pubmed

The splicing regulators Esrp1 and Esrp2 direct an epithelial splicing program essential for mammalian development.

RAP1GAP PTPRF CRNN

6.10e-045997326371508
InteractionCEP135 interactions

RTTN TOGARAM1 GIGYF1 TNRC6C CEP170 DACT1 LMO7 TNRC6A NAV1 TMEM131L

5.13e-072729310int:CEP135
InteractionTNRC6A interactions

GIGYF1 TNRC6C KANK2 UBE2O UBAP2L TNRC6A TNKS1BP1 EIF2AK4 DTX2 MED13

6.69e-072809310int:TNRC6A
InteractionTOP3B interactions

SPEG RTTN TNRC6C MAST2 KANK2 IFNLR1 DACT1 PTPRF SETD5 UBAP2L PTPRS USP40 NAV2 NAV1 NLE1 RIPOR1 TNKS1BP1 DTX2 ATG9A HECTD1 MED13

2.62e-0614709321int:TOP3B
InteractionCNOT9 interactions

KIAA0232 GIGYF1 TNRC6C JMJD1C UBAP2L TNRC6A TMEM131L TNKS1BP1

1.16e-05231938int:CNOT9
InteractionJPH4 interactions

ZSWIM8 KBTBD7 VANGL2 UBE2O GCC1

1.56e-0568935int:JPH4
InteractionGIGYF1 interactions

GIGYF1 TNRC6C UBAP2L TNRC6A DACT3 NAV1 CAMSAP2

1.80e-05177937int:GIGYF1
InteractionCNOT2 interactions

KIAA0232 GIGYF1 TNRC6C JMJD1C UBAP2L TNRC6A TNKS1BP1

1.86e-05178937int:CNOT2
InteractionMED4 interactions

XRCC4 KANK2 CEP170 UBE2O UBAP2L TNRC6A NAV1 GCC1 HECTD1 MED13

4.31e-054509310int:MED4
InteractionCNOT6L interactions

KIAA0232 TNRC6C UBAP2L TNRC6A TNKS1BP1

7.08e-0593935int:CNOT6L
GeneFamilyPDZ domain containing

PCLO FRMPD2 MAST2 LMO7 GRIP2

8.92e-051525451220
GeneFamilyFibronectin type III domain containing

PTPRF PTPRS ROBO2 ROS1 USH2A

1.14e-04160545555
GeneFamilyBlood group antigens|CD molecules|I-set domain containing|Immunoglobulin like domain containing

SPEG PTPRF PTPRS ROBO2

1.35e-03161544593
GeneFamilyProtein tyrosine phosphatases, receptor type

PTPRF PTPRS

1.77e-0321542813
GeneFamilyCD molecules|Mucins

MUC19 MUC16

1.77e-0321542648
GeneFamilyAtaxins|Trinucleotide repeat containing

TNRC6C TNRC6A

2.51e-0325542775
CoexpressionMANNO_MIDBRAIN_NEUROTYPES_HGABA

SPEG PCLO CPEB3 MUC19 GIGYF1 TNRC6C DACT1 KIAA1549L TNRC6A DACT3 FAM217B NAV1 ROBO2 GRIP2 CAMSAP2

8.89e-0611069415M39071
ToppCellControl-Epithelial|Control / Disease state, Lineage and Cell class

ATP13A4 SYNE1 PTPRF LMO7 DMKN SUSD2 NAV2 ROS1

1.03e-081959681798c3b89b1b5ff4f5777d2b9f52dc81cdad28fa
ToppCellCOPD-Epithelial|COPD / Disease state, Lineage and Cell class

ATP13A4 PTPRF LMO7 DMKN SUSD2 NAV2 ROS1

2.00e-071929670644fad5df18f0021f6f49cca996d8cf47f972ff
ToppCellParenchymal-10x5prime-Epithelial-Epi_alveolar-Dividing_AT2|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

PTPRF LMO7 DMKN SUSD2 NAV2 TNKS1BP1 ROS1

2.07e-0719396744839a606ae2f8e37421bda46d588189e1c943d2
ToppCellLung_Parenchyma-Control-Epithelial|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

RAP1GAP SYNE1 PTPRF LMO7 DMKN SUSD2 ROS1

2.63e-07200967c2bde99b3bc7a8740441c1a0c1394892b940b857
ToppCellLung_Parenchyma-Control-Epithelial-Epithelial|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

RAP1GAP SYNE1 PTPRF LMO7 DMKN SUSD2 ROS1

2.63e-072009673ff9abd5e07780a59d5571da906fa15f00a1d5c2
ToppCellParenchyma_Control_(B.)-Epithelial-TX|Parenchyma_Control_(B.) / Sample group, Lineage and Cell type

RAP1GAP SYNE1 PTPRF LMO7 DMKN SUSD2 ROS1

2.63e-072009679970e9bde6aa2ff3aef60dcb065ff15b7463e147
ToppCellBiopsy_Other_PF-Epithelial-SCGB3A2+|Biopsy_Other_PF / Sample group, Lineage and Cell type

ATP13A4 PTPRF LMO7 DMKN SUSD2 NAV2 ROS1

2.63e-07200967631550dc34bcb605ab726645f4024d7828bb7975
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-precursor_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MUC19 MYOCOS KIAA1549L SPHKAP TDRD6 USH2A

1.31e-06160966c381ec6be8cf887861cc18f831a20db42f953fe1
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-pre_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MUC19 MYOCOS KIAA1549L SPHKAP TDRD6 USH2A

1.31e-0616096625c8f3d2a6d14ff0ca0b965fce89d3ff22f40585
ToppCellAT2_cells-Myositis-ILD_01|World / lung cells shred on cell class, cell subclass, sample id

SYNE1 PTPRF DMKN SUSD2 ROBO2 ROS1

2.68e-06181966ed0ea67f0607073aedf153f8d1073b35e46127c3
ToppCellCOPD-Epithelial-ATII|World / Disease state, Lineage and Cell class

ATP13A4 RAP1GAP SYNE1 LMO7 SUSD2 ROS1

2.85e-061839668e9aab4eeec2e282c2cab9bfca6dbf40d660c7b9
ToppCellSmart-seq2-blood_(Smart-seq2)-myeloid-myeloid_monocytic-classical_monocyte|blood_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

PCLO MUC19 MUC16 JMJD1C NAV1 USH2A

3.13e-0618696623b8d51d20b05795a73892d3e20e0f9b6a207820
ToppCellCOVID-19-Epithelial_cells|COVID-19 / group, cell type (main and fine annotations)

ATP13A4 PTPRF LMO7 DMKN NAV2 ROS1

3.33e-06188966c9cdee6f8d42ee69f5fb335f25084603c511bd29
ToppCellfacs-Pancreas-Endocrine-24m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SEC16B PCLO KY PTPRF NAV2 NAV1

3.33e-06188966a91443aa8fa8fa87f7501c59219daa0305bd0bbf
ToppCellLAM-Epithelial-AT1|LAM / Condition, Lineage and Cell class

ATP13A4 PTPRF LMO7 DMKN SUSD2 NAV2

3.65e-0619196666875b2ec2c510489407f3e433a90cdf74a15094
ToppCellfacs-Pancreas-Endocrine-3m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PCLO MDM1 KY SPHKAP ROBO2 USH2A

3.76e-061929665b7093d5af5ae7b0e6d3a464cc56272440ecedad
ToppCellControl-Multiplet|Control / Disease state, Lineage and Cell class

ATP13A4 SYNE1 LMO7 DMKN NAV2 ROS1

4.11e-06195966618900c80bea09d46dad3f741bd1bff8bf0a64ee
ToppCellControl-Multiplet-Multiplet|Control / Disease state, Lineage and Cell class

ATP13A4 SYNE1 LMO7 DMKN NAV2 ROS1

4.11e-0619596606ac685855e14e4dd2cbe6d0e73f894f2eeff91f
ToppCellnucseq-Epithelial|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

ATP13A4 SYNE1 PTPRF LMO7 NAV2 ROS1

4.11e-061959669406866f99555198a9be311fbd65751b70f35446
ToppCelldroplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PCLO KY PTPRF SPHKAP NAV2 ROBO2

4.11e-061959667796ea9247f4c63762f0de8490fed08b9717fa23
ToppCell5'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2-AT2_L.0.1.2.3|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ATP13A4 MXRA8 LMO7 DMKN SUSD2 ROS1

4.24e-06196966784459f9f3614ead947aeb61a873dfd4cbe50641
ToppCellBiopsy_Other_PF-Epithelial-AT2|Biopsy_Other_PF / Sample group, Lineage and Cell type

RAP1GAP SYNE1 LMO7 DMKN SUSD2 ROS1

4.62e-061999669a65acfe9bf500db72142469cf17bf0973540001
ToppCellParenchymal-10x5prime-Epithelial-Epi_alveolar-AT1|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

ATP13A4 PTPRF LMO7 DMKN SUSD2 NAV2

4.62e-06199966aca81a879ef9c196bd1885eff4c63ffe6c9682b7
ToppCellParenchymal-10x3prime_v2-Epithelial-Epi_alveolar|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

RAP1GAP PTPRF LMO7 DMKN SUSD2 ROS1

4.62e-061999667ebd89dff457f57a549eecee288c7a4b515b4018
ToppCellBronchial-10x5prime-Epithelial-Epi_alveolar|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

ATP13A4 RAP1GAP LMO7 DMKN SUSD2 ROS1

4.62e-06199966a38a981cffa61c8444a980916de7414e689a1b63
ToppCellParenchyma_COVID-19-Epithelial-TX-Transitional_AT2|Parenchyma_COVID-19 / Sample group, Lineage and Cell type

ATP13A4 PTPRF LMO7 DMKN SUSD2 ROS1

4.76e-06200966dfa897ef5ce4744c77b6e5ee5a0d6d83229d1691
ToppCellLung_Parenchyma-Control-Epithelial-Epithelial-AT2-1-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

RAP1GAP PCLO LMO7 DMKN SUSD2 ROS1

4.76e-0620096665c83a3f6ee2a10bcb5b95076696232c6373a7b4
ToppCellLung_Parenchyma-Control-Epithelial-Epithelial-AT2-1|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

RAP1GAP PCLO LMO7 DMKN SUSD2 ROS1

4.76e-0620096640e969883bc302e8fbc6b6ab9814529dc1472902
ToppCellLung_Parenchyma-Severe-Epithelial-Epithelial-Transitional_AT2-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

ATP13A4 PTPRF LMO7 DMKN SUSD2 ROS1

4.76e-062009668d1c78dd829cbc290820d5118f24ff7f828a8622
ToppCellParenchyma_Control_(B.)-Epithelial-TX-AT2-1|Parenchyma_Control_(B.) / Sample group, Lineage and Cell type

RAP1GAP PCLO LMO7 DMKN SUSD2 ROS1

4.76e-06200966ad9cdc82a647d379abc713a56db0e11bb6494106
ToppCellParenchymal-10x5prime-Epithelial-Epi_alveolar|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

ATP13A4 RAP1GAP LMO7 DMKN SUSD2 ROS1

4.76e-06200966b2d61bc3afac0d78aa30082760da5b1a15d1fad2
ToppCellBronchial-10x5prime-Epithelial-Epi_alveolar-AT2|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

RAP1GAP LMO7 DMKN SUSD2 FGA ROS1

4.76e-06200966b535323e18d9fb0dde1e0026df142c831e48c29f
ToppCellParenchymal-10x5prime-Epithelial|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

ATP13A4 PTPRF LMO7 DMKN SUSD2 ROS1

4.76e-062009664e5b6cb014d9bcb58e13c7511c86c43e27c496e4
ToppCellLung_Parenchyma-Severe-Epithelial-Epithelial-Transitional_AT2|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

ATP13A4 PTPRF LMO7 DMKN SUSD2 ROS1

4.76e-06200966992bd6b1feac2afded6eb927ac95ddf5cfef961c
ToppCellTCGA-Ovary-Primary_Tumor-Ovarian_Carcinoma-Serous_Cystadenocarcinoma-5|TCGA-Ovary / Sample_Type by Project: Shred V9

DCAF6 BBX PTPRF UBAP2L USP40

3.00e-0516696532d2eaf8a5d03881bf74d680825af2d5110b082d
ToppCelldroplet-Pancreas-Endocrine-18m-Epithelial-nan|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADGRG3 PCLO MDM1 TNRC6A GRIP2

3.00e-0516696566026988509e39e41274fa0de738383219e8ff30
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Degenerative_Fibroblast-Degenerative_Fibroblast_104|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ZNRD2 MUC19 DACT1 DACT3 TDRD6

3.00e-05166965c11dcf9705b85ac3da6ae86358f5ffd64ae8327e
ToppCellControl|World / group, cell type (main and fine annotations)

ATP13A4 SYNE1 LMO7 NAV2 ROS1

3.18e-05168965a3511faf2cd2c2b9c8363c8b99da3f3609c43ed6
ToppCell367C-Epithelial_cells-Epithelial-B_(AT2)|367C / Donor, Lineage, Cell class and subclass (all cells)

PTPRF LMO7 DMKN SUSD2 OSBP2

3.18e-05168965e20e1936573fdde78426d7a4eb45c458d5c4dbb4
ToppCell367C-Epithelial_cells-Epithelial-B_(AT2)-|367C / Donor, Lineage, Cell class and subclass (all cells)

PTPRF LMO7 DMKN SUSD2 OSBP2

3.18e-0516896516b517e3159ad6e6d25fd48f7d5f46e77b2b318d
ToppCelldroplet-Spleen-nan-3m-Myeloid-granulocyte|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADGRG3 SYNE1 IFNLR1 DMKN MXD1

3.36e-05170965dbd6c9c7be824a1ff1b31af791064127cafbd194
ToppCellfacs-Marrow-Granulocytes-3m-Myeloid-macrophage|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KANK2 ARHGAP22 PTPRF DACT3 GRIP2

3.55e-051729657fb31ccbcd0204c3612986a6bc20d57ed6825e9c
ToppCellfacs-Marrow-Granulocytes-3m-Myeloid-CD4+_macrophage|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KANK2 ARHGAP22 PTPRF DACT3 GRIP2

3.55e-051729652a4614b3d25e8c6b095e6992d8ca35371dcdb5e1
ToppCell356C-Myeloid-Macrophage-FABP4+_Macrophage_4|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

RAP1GAP KBTBD7 DMKN PTPRS SUSD2

3.65e-05173965ef8d720b99470fe1953661f6e66bc0366266bdb6
ToppCell356C-Myeloid-Macrophage-FABP4+_Macrophage_4|Macrophage / Donor, Lineage, Cell class and subclass (all cells)

RAP1GAP DMKN PTPRS SUSD2 TNKS1BP1

3.76e-05174965110369f6b78de34a6d934b5b47cecd023347bc80
ToppCell368C-Epithelial_cells-Epithelial-B_(AT2)-|368C / Donor, Lineage, Cell class and subclass (all cells)

RAP1GAP PCLO LMO7 ROS1 OSBP2

4.07e-05177965ac8f774596068e66c0a9ea8a318be0ce5f5df834
ToppCell368C-Epithelial_cells-Epithelial-B_(AT2)|368C / Donor, Lineage, Cell class and subclass (all cells)

RAP1GAP PCLO LMO7 ROS1 OSBP2

4.07e-05177965d9c4a93b0e04a13bf39992dd1c1ec8df2c5f89fe
ToppCellLPS-antiTNF-Epithelial_alveolar-AT_1-Differentiating_AT1|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ATP13A4 PTPRF LMO7 SUSD2 NAV2

4.53e-05181965b45b11428d13950369347e051d4d517efb2bd4fd
ToppCellPND14-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1-AT1_mature|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ATP13A4 ARHGAP22 PTPRF LMO7 NAV2

4.65e-05182965573771130247e869e4e58f22d4a1cb31989635cf
ToppCellPND14-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ATP13A4 ARHGAP22 PTPRF LMO7 NAV2

4.65e-051829656cfaa2b3b3974c13b01c943f4adb70768dcc35e4
ToppCellCOPD-Epithelial-ATI|World / Disease state, Lineage and Cell class

ATP13A4 PTPRF LMO7 SUSD2 NAV2

4.65e-05182965e95d946a43b1579af199900bb0e3eacbb9d65300
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_5|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SEC16B FRMPD2 PTGFRN SLC5A4 DMKN

4.77e-05183965b5d041d0a3506c33de72bf14fa0443f4410fddf1
ToppCellCOVID-19-lung-AT1|COVID-19 / Disease (COVID-19 only), tissue and cell type

ATP13A4 PTPRF LMO7 DMKN NAV2

4.77e-051839657b1a385ed54f93bfe85bf0c162e42d05d516b45c
ToppCellIPF-Epithelial-ATI|World / Disease state, Lineage and Cell class

ATP13A4 PTPRF LMO7 SUSD2 NAV2

4.77e-0518396531fef35ecf30162662f24d335d8f0cceacc07039
ToppCellCOVID-19-Epithelial_cells-ECM-high_epithelial|COVID-19 / group, cell type (main and fine annotations)

ATP13A4 LMO7 NAV2 ROBO2 ROS1

4.77e-05183965dc1d380bf7564f290256cb7108063d1bd2da732b
ToppCellControl-Stromal_mesenchymal-Lung_smooth_muscle-MatrixFB_->_Myofibroblast|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

KANK2 PTPRS SPHKAP DACT3 ROBO2

4.77e-051839657eae9b3b4d1c9b135fa7cff348393d4adec474b4
ToppCellLPS-antiTNF-Epithelial_alveolar-AT_1|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ATP13A4 PTPRF LMO7 SUSD2 NAV2

4.77e-05183965ff6dde877659cde9daa3263db0932c9c9ef1adac
ToppCellLPS_only-Stromal_mesenchymal-Lung_smooth_muscle-MatrixFB_->_Myofibroblast|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

MXRA8 PTPRS SPHKAP DACT3 ROBO2

4.77e-0518396512daaea821e49bc94a01e2496331e92a80d27339
ToppCellAT1-AT2_cells-Donor_02|World / lung cells shred on cell class, cell subclass, sample id

ATP13A4 PCLO MXRA8 KANK2 PTPRF

4.77e-051839656821dca076318115d360ff426eb1218cfe104063
ToppCell367C-Epithelial_cells-Epithelial-A_(AT2)|367C / Donor, Lineage, Cell class and subclass (all cells)

RAP1GAP PTPRF DMKN SUSD2 ROS1

4.90e-051849650ba243cbf69b4fe6ae100a7f0314317bec38026c
ToppCell367C-Epithelial_cells-Epithelial-A_(AT2)-|367C / Donor, Lineage, Cell class and subclass (all cells)

RAP1GAP PTPRF DMKN SUSD2 ROS1

4.90e-051849652a8338e94937686a148b5433515700ca0f674058
ToppCellIPF-Epithelial-ATII|IPF / Disease state, Lineage and Cell class

ATP13A4 RAP1GAP LMO7 SUSD2 ROS1

5.03e-05185965563b4e6d92bb5d77a3829556116a8e99aebac615
ToppCellLPS-IL1RA+antiTNF-Epithelial_alveolar-AT_1-Differentiating_AT1|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ATP13A4 PTPRF LMO7 SUSD2 NAV2

5.16e-051869653aebe163799109ffc67e4e10ee47c2dd0886a92c
ToppCellControl-Epithelial-Club|World / Disease state, Lineage and Cell class

ATP13A4 LMO7 SUSD2 NAV2 ROS1

5.16e-051869659798428691408e17ff2af2fe2d1b345f074d67e4
ToppCellCOPD-Epithelial-ATI|COPD / Disease state, Lineage and Cell class

ATP13A4 PTPRF LMO7 SUSD2 NAV2

5.16e-05186965df0977f6f48a2d4e11b59971f098b01204242f0f
ToppCellCOPD-Epithelial-Club|World / Disease state, Lineage and Cell class

ATP13A4 LMO7 SUSD2 NAV2 ROS1

5.16e-051869653006f4ab1eaf1eb34c10ca9f7c869603d2d25744
ToppCell367C-Epithelial_cells-Epithelial-E_(AT2)-|367C / Donor, Lineage, Cell class and subclass (all cells)

RAP1GAP LMO7 DMKN SUSD2 ROS1

5.29e-0518796511670a85db87cbb3e78022a589632173604b0940
ToppCellLPS-antiTNF-Epithelial_alveolar-AT_1-Differentiating_AT2|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ATP13A4 PTPRF LMO7 NAV2 TNKS1BP1

5.29e-0518796558d48128547ee3513d0bf7f78e61b76b1c472ca9
ToppCell368C-Epithelial_cells-Epithelial-G_(Club-Clara_cells)|368C / Donor, Lineage, Cell class and subclass (all cells)

ATP13A4 CPEB3 KBTBD7 SUSD2 ROS1

5.29e-05187965b827d9da7032bf051756ddf88352af922eb0f87b
ToppCell368C-Epithelial_cells-Epithelial-G_(Club-Clara_cells)-|368C / Donor, Lineage, Cell class and subclass (all cells)

ATP13A4 CPEB3 KBTBD7 SUSD2 ROS1

5.29e-0518796561c00604dda8b36a5c3eea6554e5601aa1b884f7
ToppCell367C-Epithelial_cells-Epithelial-E_(AT2)|367C / Donor, Lineage, Cell class and subclass (all cells)

RAP1GAP LMO7 DMKN SUSD2 ROS1

5.29e-051879650277d4e54bd4d48f30241c2951a569209423fee8
ToppCellCOPD-Epithelial-ATII|COPD / Disease state, Lineage and Cell class

ATP13A4 RAP1GAP LMO7 SUSD2 ROS1

5.43e-05188965eb6d79d733b53f64ca615bb777c64ed456866549
ToppCell368C-Epithelial_cells-Epithelial-E_(AT2)|368C / Donor, Lineage, Cell class and subclass (all cells)

RAP1GAP LMO7 DMKN SUSD2 ROS1

5.56e-051899656f2322d017b74a1757c81d6e06f50ead8c3dd0cc
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

SPEG KANK2 DACT3 TMEM131L GRIP2

5.56e-051899657fbe855bfdb47d35e040b04a80fe4b729a3764e8
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

SPEG KANK2 DACT3 TMEM131L GRIP2

5.56e-0518996506b35abecd29f902cf251fcc1f6ad33db7ab08a2
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SPEG DACT3 TMEM131L ROBO2 GRIP2

5.56e-05189965127ad2ba3e794df8cce2eee3e4171bccb5aad51b
ToppCellPND07-28-samps-Mesenchymal-Matrix_fibroblast|PND07-28-samps / Age Group, Lineage, Cell class and subclass

MXRA8 PTPRS DACT3 NAV2 ROBO2

5.56e-05189965dc5164591dea45b420798b94dda211be03daa70c
ToppCell(1)_Osterolineage_cells-(10)_OLC-1|World / Cell class and subclass of bone marrow stroma cells in homeostatis

MXRA8 LMO7 PTPRS NAV2 ROBO2

5.56e-0518996546c5b975fb9d33017f2d9b7770d45a8bdf95baa2
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SPEG DACT3 TMEM131L ROBO2 GRIP2

5.56e-051899652cfb4d12f75678d1619f4743838a0e954bd57761
ToppCellAT2_cells-Cryobiopsy_01|World / lung cells shred on cell class, cell subclass, sample id

RAP1GAP PTPRF DMKN SUSD2 ROS1

5.56e-051899652d32f09efa982ae458568f6b1cd06bb5078d42a3
ToppCellIPF-Epithelial-Club|IPF / Disease state, Lineage and Cell class

ATP13A4 LMO7 SUSD2 NAV2 ROS1

5.56e-05189965f3fcef008ef252b29ac6d567fef27f9acf9cd70f
ToppCell368C-Epithelial_cells-Epithelial-E_(AT2)-|368C / Donor, Lineage, Cell class and subclass (all cells)

RAP1GAP LMO7 DMKN SUSD2 ROS1

5.56e-05189965926b5fa3064b501a57ba78583e8af33532add455
ToppCellControl-Stromal_mesenchymal-Lung_smooth_muscle|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SPEG KANK2 PTPRS DACT3 ROBO2

5.56e-0518996545e588b2a4ad9e3ff74e22d9d627ed3571f3b8b8
ToppCellControl-Epithelial-ATII|Control / Disease state, Lineage and Cell class

ATP13A4 LMO7 DMKN SUSD2 ROS1

5.70e-05190965d50902a3abcc18aafa36d83cc2c6e07d7f7cb197
ToppCellPND07-28-samps-Mesenchymal-Matrix_fibroblast-FB-3|PND07-28-samps / Age Group, Lineage, Cell class and subclass

MXRA8 PTPRS DACT3 NAV2 ROBO2

5.70e-051909651196b8ea2c44c7c80f5ee589dd517e6a413f2077
ToppCelltumor_Lung-Fibroblasts-Mesothelial_cells|Fibroblasts / Location, Cell class and cell subclass

PCLO MUC16 PTPRF DMKN OSBP2

5.70e-05190965d82ab67735c1f365d4b0e02b5fa91c64cdc234da
ToppCell368C-Epithelial_cells|368C / Donor, Lineage, Cell class and subclass (all cells)

RAP1GAP LMO7 DMKN SUSD2 ROS1

5.70e-05190965459811e88d3001816c2d89034e0921c24918c17f
ToppCellCOPD-Epithelial-Club|COPD / Disease state, Lineage and Cell class

ATP13A4 LMO7 SUSD2 NAV2 ROS1

5.85e-05191965c909cf5fa0e6519aa93a47d2c3fcd2ae2163cd8d
ToppCellSmart-seq2-bone_marrow_(Smart-seq2)-myeloid-myeloid_granulocytic-neutrophil|bone_marrow_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

ADGRG3 SYNE1 MUC19 KBTBD7 MXD1

5.85e-05191965d4f77c73311d1149466bbfe4adbd6a301946ec90
ToppCell367C-Epithelial_cells|367C / Donor, Lineage, Cell class and subclass (all cells)

PTPRF LMO7 DMKN SUSD2 ROS1

5.85e-05191965d31975fc33779b0b3ff1a50d7c64fec8d08be4d4
ToppCellPND01-03-samps-Mesenchymal-Matrix_fibroblast-MatrixFB-A|PND01-03-samps / Age Group, Lineage, Cell class and subclass

MXRA8 PTPRS DACT3 NAV2 ROBO2

5.85e-05191965e7c605b56934d1383237c1f946dbccef25d91368
ToppCellIPF-Epithelial-Club|World / Disease state, Lineage and Cell class

ATP13A4 LMO7 SUSD2 NAV2 ROS1

5.85e-051919653c88a6f1d74bb3b9173cd0ea3a63c6d9570e3954
ToppCellfacs-Pancreas-Endocrine-3m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PCLO MDM1 KY SPHKAP ROBO2

5.85e-05191965f76f3f5c7902a3659d8cbe470f96ce57c8a6744d
ToppCellControl-Stromal_mesenchymal-Lung_smooth_muscle-Myofibroblast|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SPEG KANK2 PTPRS NAV2 ROBO2

5.85e-05191965b133ee1c0e58d00ddd2e4e05b01fd04947524c18
ToppCellControl-Multiplet-Multiplet|World / Disease state, Lineage and Cell class

ATP13A4 SYNE1 LMO7 SUSD2 ROS1

5.99e-051929651bfd022d5b87cf8a5d5069f559339a553a52a0a2
ToppCellEpithelial|World / Lineage, Cell type, age group and donor

ATP13A4 PTPRF LMO7 NAV2 ROS1

5.99e-05192965499e8893afea5e6d3371e0bd018f7e86a524d669
ToppCellPND10-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1-AT1_mature|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

IFNLR1 ARHGAP22 PTPRF LMO7 NAV2

5.99e-05192965790282d4232311df3dac4ad97c80fc53443beccc
ToppCellPND10-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

IFNLR1 ARHGAP22 PTPRF LMO7 NAV2

5.99e-05192965b2d9bffccd6264b4f12d88a0780646ee0b41969f
ToppCellSmart-seq2-bone_marrow_(Smart-seq2)-myeloid-myeloid_granulocytic|bone_marrow_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

ADGRG3 SYNE1 MUC19 KBTBD7 MXD1

6.14e-05193965e1855cff9a6bcfda9188b9fdf6c9d698405da990
ToppCell10x_3'_v3-bone_marrow_(10x_3'_v3)-hematologic-erythrocytic-erythrocyte|bone_marrow_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

KANK2 UBE2O PTPRF OSBP2 PHLPP2

6.14e-05193965305e15ee467826ee08b2617c69f250ad39c11b19
DiseaseNEURAL TUBE DEFECTS, SUSCEPTIBILITY TO

VANGL2 DACT1

2.72e-048932C3891448
Diseasecortical thickness

MDM1 MAST2 JMJD1C VANGL2 DACT1 PTPRF SETD5 TNRC6A NAV2 NAV1 ROBO2

7.56e-0411139311EFO_0004840
Disease5-methyluridine (ribothymidine) measurement

PCLO PTPRS

8.72e-0414932EFO_0020013
Diseasedecreased susceptibility to hepatitis C infection

PTGFRN NAV2

1.15e-0316932EFO_0010101
DiseaseQT interval

KIAA0232 MAST2 KANK2 TMEM44 USP40 TMEM131L ROS1

1.52e-03534937EFO_0004682
Diseasesensory perception of sweet taste

KRBA1 PTPRF DMKN

2.24e-0382933GO_0050916
DiseaseSjogren's syndrome (is_marker_for)

MUC19 MUC16

2.59e-0324932DOID:12894 (is_marker_for)
Diseaseplatelet component distribution width

SYNE1 KIAA0232 RTTN JMJD1C UBE2O MAVS TMEM131L EIF2AK4

2.67e-03755938EFO_0007984

Protein segments in the cluster

PeptideGeneStartEntry
DNWGETTTVVTGTSE

VANGL2

66

Q9ULK5
SEEGTSSSGSKRWVS

CEP170

571

Q5SW79
NEESWTFSQSGTSGS

BBX

656

Q8WY36
SSSVEWSTSGERSAS

EIF2AK4

706

Q9P2K8
NETTGSSSASISWTL

ATP13A4

746

Q4VNC1
TKGTTGDWSSEGCST

ADGRG3

221

Q86Y34
STSGNDDSTSLDLEW

AP1AR

196

Q63HQ0
TDEWSSIASSSRGIG

DCAF6

496

Q58WW2
TSSTTGESDTVIWNE

DTX4

561

Q9Y2E6
RGDWKTDSTSSTASS

PIK3AP1

711

Q6ZUJ8
TSSWSDQTSGSDITL

MUC16

3426

Q8WXI7
LTLDTSSTASWEGTH

MUC16

5876

Q8WXI7
SEGTLTLDTSTTTFW

MUC16

8506

Q8WXI7
GTPTSFSSSSSTDWD

KRBA1

461

A5PL33
LDWSSSSVSDSDERG

MXD1

176

Q05195
EGASSSLTVTDSTLW

MAGEA8

66

P43361
DSTLWSQSDEGSSSN

MAGEA8

76

P43361
GATGGSSAWLDSSSE

MAVS

396

Q7Z434
SASSQSGGEASLWDI

GIGYF1

651

O75420
ASTVDSSWDRAGSSG

IFNLR1

391

Q8IU57
SSATTWMEGTGILSS

HSFX4

281

A0A1B0GTS1
TSSTTGETDTVVWNE

DTX2

566

Q86UW9
VDSTWGSGLVDTITS

KY

281

Q8NBH2
SAADTTSVSSWGGSE

JMJD1C

1401

Q15652
TSVSSWGGSEVISSL

JMJD1C

1406

Q15652
TTGQAAAESSSAGTW

KIAA1109

3431

Q2LD37
GSQFWATEDATTTAS

PCLO

3346

Q9Y6V0
RSWSSGSSEAGSSSS

KIAA0232

286

Q92628
SDVSDSGGNTWSSDS

MUC19

421

Q7Z5P9
VTESWTAGTSSGGHS

MUC19

3111

Q7Z5P9
SAEVTGTTGLSAWVT

MUC19

4616

Q7Z5P9
WDLSGSGSSSKVETS

FAM217B

306

Q9NTX9
WDVSSTTSSEGTVSS

MDM1

371

Q8TC05
GDSASSQSWTSVLEA

NRDE2

946

Q9H7Z3
ATWSEGSKSSDREGT

LMO7

1301

Q8WWI1
IREAGTSVSSDFSSW

MYOCOS

86

A0A1B0GUC4
SGETWDSKFSTIASS

DPP3

491

Q9NY33
TDVFWSSLSAETGSL

KIAA1549L

396

Q6ZVL6
AGITETEWTSGSSKG

TMPO

226

P42167
SGSSSSFSDDEVWVQ

KBTBD7

656

Q8WVZ9
SSATTWMEGTGILSS

HSFX3

281

A0A1B0GWH4
GKGLEWVSSISSSSS

IGHV3-21

61

A0A0B4J1V1
AEGSTGTSSVDWSSA

OSBP2

476

Q969R2
TGASTESGRQEWSST

CRNN

406

Q9UBG3
TENTATSITITWDSG

PTPRS

341

Q13332
TAETSLGSEFVTGWT

HECTD1

801

Q9ULT8
EEASWSESGVSSSSG

GCC1

131

Q96CN9
TTTSDSEESGGLIWS

DACT1

771

Q9NYF0
SSASSDSDGSGGLVW

DACT3

561

Q96B18
SFGSTWSTGTTNAVE

CPEB3

106

Q8NE35
SRGDSGSESSWGSST

DMKN

296

Q6E0U4
SGSVHSAADSSWPTT

FRMPD2

281

Q68DX3
GVDARTASSGSSVWE

ATG9A

676

Q7Z3C6
ERGSAGHWTSESSVS

FGA

366

P02671
ESSVSGSTGQWHSES

FGA

376

P02671
SSVGQVTWQSSGEAS

MAST2

121

Q6P0Q8
STASESSASLGSEWD

DENND4B

1106

O75064
SSASLGSEWDLSESS

DENND4B

1111

O75064
GSEWDLSESSLSNLS

DENND4B

1116

O75064
WTSTESLCSNASGDS

KANK2

81

Q63ZY3
DSAVESWDSSATEGG

GRIP2

781

Q9C0E4
DWENASTTSSVASGT

CAMSAP2

1331

Q08AD1
SATAAASSGLEEWTS

OTUD5

436

Q96G74
TATSVTLTWDSGNSE

PTPRF

331

P10586
ITTGWDESSSISSGL

NAV1

406

Q8NEY1
SSLGSSFVELASTWE

PTGFRN

61

Q9P2B2
DGQDWDAASSSGSSS

RTTN

326

Q86VV8
SGSGDTTVRFWDLST

NLE1

131

Q9NVX2
GSVSSAWVSERTGES

USH2A

1346

O75445
SSSEESTGSWTQLAN

SPHKAP

1511

Q2M3C7
ETSTCQADGTWSSPT

SUSD2

761

Q9UGT4
VWGDSISSTAVSTAA

TNRC6C

536

Q9HCJ0
EALSVSSGSWSSATV

TP53AIP1

66

Q9HCN2
TGTGDENSTSATWEE

TDRD6

291

O60522
SWSSADELDTSGSVS

SYNE1

8671

Q8NF91
SWGSWSSTSSSDGDK

TMEM131L

1321

A2VDJ0
ESGFWSADETSTASS

GPRASP2

221

Q96D09
SADETSTASSFWTGE

GPRASP2

226

Q96D09
STASSFWTGEETSVR

GPRASP2

231

Q96D09
SWDDSSSVSSGISDT

NAV2

946

Q8IVL1
SFTLDTWSTSRGDTA

SGPP1

306

Q9BX95
TWSTSRGDTAEILGS

SGPP1

311

Q9BX95
TWLEDSVSTTSGGSS

RAP1GAP

611

P47736
DNISGGDSSATESWD

SETD5

126

Q9C0A6
GAASGVATVTFEWTS

SLC5A4

91

Q9NY91
NTDESTNSSSVWTLG

MED13

1651

Q9UHV7
AWSGASSSESSVGGS

ARHGAP22

511

Q7Z5H3
WDSDTPSSGSCATVS

PHF13

171

Q86YI8
QSGSTTTSSWDMGST

UBAP2L

381

Q14157
DSTVTSTFWSHGLAE

PHLPP2

776

Q6ZVD8
ASWGSEDSLSVASDL

SPEG

241

Q15772
KSTSGLTDITWSSSG

SPIDR

91

Q14159
LTDITWSSSGSDLSD

SPIDR

96

Q14159
SQTEDVDGTWGSSAA

TNKS1BP1

1516

Q9C0C2
DWEKTGNDGSLTTTT

TTBK2

296

Q6IQ55
LTDGHSAWTGTVSES

XRCC4

36

Q13426
SVEGSTSGASSDEWE

UBE2O

721

Q9C0C9
TVSTDSWGQRLGSSE

ZNF646

121

O15015
GSSSEVSSINSDLEW

TMEM44

426

Q2T9K0
TSSSGETSWSAVLDV

ROBO2

491

Q9HCK4
STGDTTITEFAAWST

ROS1

866

P08922
SSVAVTEATGGTVWE

SEC16B

811

Q96JE7
LTWASAELGSSTSLE

ZNRD2

161

O60232
TSWGRGQDSDSISSS

ZSWIM8

1171

A7E2V4
EAVSSSWSESGGGLS

TOGARAM1

76

Q9Y4F4
GTAWSLSSESSDDSS

RIPOR1

376

Q6ZS17
AASTADLTDSFGWTS

USP40

111

Q9NVE5
TDNGTEAWGSSATQT

TNRC6A

746

Q8NDV7
AAASSTSTWGSSSVG

TNRC6A

1096

Q8NDV7
AAGSSVVSESAVSWE

MXRA8

31

Q9BRK3
SVSNDLWGDFSTASS

NECAP1

246

Q8NC96
TADIWGDFTKSTGST

NECAP2

236

Q9NVZ3