Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	DNA-binding transcription activator activity, RNA polymerase II-specific	FOXO3 TCF12 EGR3 SOX30 ETV1 POU1F1 PLAG1 DLX2 CDC5L PBX2	2.13e-05	560	69	10	GO:0001228
GeneOntologyMolecularFunction	DNA-binding transcription activator activity	FOXO3 TCF12 EGR3 SOX30 ETV1 POU1F1 PLAG1 DLX2 CDC5L PBX2	2.34e-05	566	69	10	GO:0001216
GeneOntologyMolecularFunction	DNA-binding transcription factor activity, RNA polymerase II-specific	TBX15 FOXO3 GTF2IRD2B TCF12 EGR3 SOX30 GTF2IRD2 ETV1 POU1F1 PLAG1 HBP1 DLX2 CDC5L PBX2 ZNF281	7.68e-05	1412	69	15	GO:0000981
GeneOntologyMolecularFunction	RNA polymerase II cis-regulatory region sequence-specific DNA binding	TBX15 FOXO3 TCF12 EGR3 SOX30 ETV1 POU1F1 PLAG1 HBP1 DLX2 PBX2 ZNF281 MED12	2.94e-04	1244	69	13	GO:0000978
GeneOntologyMolecularFunction	cis-regulatory region sequence-specific DNA binding	TBX15 FOXO3 TCF12 EGR3 SOX30 ETV1 POU1F1 PLAG1 HBP1 DLX2 PBX2 ZNF281 MED12	3.61e-04	1271	69	13	GO:0000987
GeneOntologyMolecularFunction	RNA polymerase II transcription regulatory region sequence-specific DNA binding	TBX15 FOXO3 TCF12 EGR3 SOX30 ETV1 POU1F1 PLAG1 HBP1 DLX2 CDC5L PBX2 ZNF281 MED12	3.98e-04	1459	69	14	GO:0000977
GeneOntologyMolecularFunction	BMP receptor binding	ELAPOR2 BMP5	8.96e-04	13	69	2	GO:0070700
GeneOntologyMolecularFunction	transcription factor binding	FOXO3 CCNT2 MDFIC TCF12 PDCD11 POU1F1 CDC5L PBX2 MED12	1.10e-03	753	69	9	GO:0008134
HumanPheno	Skin detachment	COL17A1 ITGB4	1.78e-05	2	22	2	HP:0032156
HumanPheno	Compulsive behaviors	CLCN3 TCF20 MAP1B GTF2IRD2 TRRAP MED12	4.00e-05	158	22	6	HP:0000722
HumanPheno	Atrophic, patchy alopecia	COL17A1 ITGB4	5.33e-05	3	22	2	HP:0004529
HumanPheno	Partial agenesis of the corpus callosum	TCF12 CLCN3 TNR MED12	9.50e-05	58	22	4	HP:0001338
HumanPheno	Abnormal hand morphology	TBX15 TCF12 COL17A1 CLCN3 TCF20 MAP1B GTF2IRD2 POU1F1 PLAG1 TRRAP ITGB4 MED12 AFF4	1.20e-04	1082	22	13	HP:0005922
MousePheno	decreased diameter of humerus	TBX15 BMP5	1.69e-05	2	58	2	MP:0008154
Domain	-	GTF2IRD2B GTF2IRD2	7.80e-05	4	68	2	3.90.1460.10
Domain	GTF2I	GTF2IRD2B GTF2IRD2	7.80e-05	4	68	2	PS51139
Domain	GTF2I	GTF2IRD2B GTF2IRD2	7.80e-05	4	68	2	PF02946
Domain	GTF2I	GTF2IRD2B GTF2IRD2	7.80e-05	4	68	2	IPR004212
Pubmed	A census of human transcription factors: function, expression and evolution.	TBX15 FOXO3 TCF12 EGR3 SOX30 ETV1 POU1F1 PLAG1 HBP1 DLX2 CDC5L PBX2 ZNF281	2.41e-08	908	69	13	19274049
Pubmed	Impact of cytosine methylation on DNA binding specificities of human transcription factors.	TBX15 FOXO3 TCF12 EGR3 SOX30 ETV1 POU1F1 DLX2 ZNF281	1.29e-06	544	69	9	28473536
Pubmed	MECP2 directly interacts with RNA polymerase II to modulate transcription in human neurons.	CCNT2 TCF20 MAP1B SNRNP40 UPF1 POLDIP2 CDC5L TRRAP ZNF281 MED12 AFF4 HSP90AB1	1.33e-06	1082	69	12	38697112
Pubmed	R2TP/Prefoldin-like component RUVBL1/RUVBL2 directly interacts with ZNHIT2 to regulate assembly of U5 small nuclear ribonucleoprotein.	MAP1B SNRNP40 UPF1 POLDIP2 CDC5L TRRAP HSP90AB1	2.26e-06	300	69	7	28561026
Pubmed	Interactome of vertebrate GAF/ThPOK reveals its diverse functions in gene regulation and DNA repair.	TCF12 TCF20 SNRNP40 UPF1 PBX2 ZNF281 DENND4C	3.53e-06	321	69	7	32098917
Pubmed	Interaction of transcription factor FoxO3 with histone acetyltransferase complex subunit TRRAP modulates gene expression and apoptosis.	FOXO3 TRRAP	3.88e-06	2	69	2	35151693
Pubmed	Comparison of TFII-I gene family members deleted in Williams-Beuren syndrome.	GTF2IRD2B GTF2IRD2	3.88e-06	2	69	2	15388857
Pubmed	Role of primary afferents in the developmental regulation of motor axon synapse numbers on Renshaw cells.	EGR3 ETV1	3.88e-06	2	69	2	26660356
Pubmed	Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst.	TBX15 FOXO3 TCF12 TCF20 ZDHHC14 ETV1 PLAG1 HBP1 CDC5L PBX2	4.28e-06	808	69	10	20412781
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	FOXO3 PRUNE2 PCYOX1L MAP1B ZDHHC14 ETV1 ASTN2 QSER1 PBX2 TRRAP AFF4 AGAP1 DNAH1	6.36e-06	1489	69	13	28611215
Pubmed	PTPN14 regulates Roquin2 stability by tyrosine dephosphorylation.	MAP1B SNRNP40 PDCD11 UPF1 POLDIP2 QSER1 CDC5L ZNF281 HSP90AB1	7.71e-06	678	69	9	30209976
Pubmed	Transcription and Signaling Regulators in Developing Neuronal Subtypes of Mouse and Human Enteric Nervous System.	FOXO3 BMP5 TCF12 ETV1 DLX2 PBX2	1.09e-05	251	69	6	29031500
Pubmed	The Asprosin-OLFR734 hormonal signaling axis modulates male fertility.	OR4M2 OR4M1	1.16e-05	3	69	2	31798959
Pubmed	The Asprosin-OLFR734 module regulates appetitive behaviors.	OR4M2 OR4M1	1.16e-05	3	69	2	32337066
Pubmed	Isolation and characterisation of GTF2IRD2, a novel fusion gene and member of the TFII-I family of transcription factors, deleted in Williams-Beuren syndrome.	GTF2IRD2B GTF2IRD2	1.16e-05	3	69	2	15100712
Pubmed	Direct interaction between the intracellular domains of bullous pemphigoid antigen 2 (BP180) and beta 4 integrin, hemidesmosomal components of basal keratinocytes.	COL17A1 ITGB4	1.16e-05	3	69	2	9500991
Pubmed	SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.	TCF20 MAP1B PDCD11 UPF1 QSER1 CDC5L TRRAP MED12	1.32e-05	549	69	8	38280479
Pubmed	The variant Polycomb Repressor Complex 1 component PCGF1 interacts with a pluripotency sub-network that includes DPPA4, a regulator of embryogenesis.	TCF20 GPS2 MUC16 POU1F1 UPF1 CDC5L ZNF281	1.38e-05	396	69	7	26687479
Pubmed	Proximity-dependent Mapping of the Androgen Receptor Identifies Kruppel-like Factor 4 as a Functional Partner.	TCF20 GPS2 QSER1 ZNF281 MED12 AFF4	1.58e-05	268	69	6	33640491
Pubmed	Human transcription factor protein interaction networks.	C3P1 TCF12 TCF20 SEC24A GPS2 PDCD11 UPF1 POLDIP2 QSER1 PBX2 TRRAP ZNF281	2.23e-05	1429	69	12	35140242
Pubmed	Hemidesmosome formation is initiated by the beta4 integrin subunit, requires complex formation of beta4 and HD1/plectin, and involves a direct interaction between beta4 and the bullous pemphigoid antigen 180.	COL17A1 ITGB4	2.32e-05	4	69	2	9660880
Pubmed	TFII-I gene family during tooth development: candidate genes for tooth anomalies in Williams syndrome.	GTF2IRD2B GTF2IRD2	2.32e-05	4	69	2	17823943
Pubmed	Evolution of general transcription factors.	GTF2IRD2B GTF2IRD2	2.32e-05	4	69	2	23229069
Pubmed	GTF2IRD2 from the Williams-Beuren critical region encodes a mobile-element-derived fusion protein that antagonizes the action of its related family members.	GTF2IRD2B GTF2IRD2	2.32e-05	4	69	2	22899722
Pubmed	Developmental regulators containing the I-mfa domain interact with T cyclins and Tat and modulate transcription.	CCNT2 MDFIC	2.32e-05	4	69	2	17289077
Pubmed	Transmembrane collagen XVII modulates integrin dependent keratinocyte migration via PI3K/Rac1 signaling.	COL17A1 ITGB4	2.32e-05	4	69	2	24505282
Pubmed	Role of binding of plectin to the integrin beta4 subunit in the assembly of hemidesmosomes.	COL17A1 ITGB4	2.32e-05	4	69	2	14668477
Pubmed	OLFR734 Mediates Glucose Metabolism as a Receptor of Asprosin.	OR4M2 OR4M1	2.32e-05	4	69	2	31230984
Pubmed	Haploinsufficiency of Gtf2i, a gene deleted in Williams Syndrome, leads to increases in social interactions.	GTF2IRD2B GTF2IRD2	2.32e-05	4	69	2	21328569
Pubmed	The DNA sequence and analysis of human chromosome 6.	FOXO3 TRAF3IP2 BMP5 VNN2 ZDHHC14 CDC5L PBX2 HSP90AB1	3.21e-05	622	69	8	14574404
Pubmed	Genetic and Proteomic Interrogation of Lower Confidence Candidate Genes Reveals Signaling Networks in β-Catenin-Active Cancers.	CCNT2 NEBL GPS2 SNRNP40 UPF1 CDC5L ZNF281 MED12 AFF4 DNAH1 HSP90AB1	3.26e-05	1247	69	11	27684187
Pubmed	Structure and function of hemidesmosomes: more than simple adhesion complexes.	COL17A1 ITGB4	3.86e-05	5	69	2	10201522
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	ADAM19 ASTN2 TAOK1 POLDIP2 RAB11FIP4 PBX2 DSCAML1 AFF4 KRIT1 AGAP1 HSP90AB1	4.28e-05	1285	69	11	35914814
Pubmed	Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes.	FOXO3 TCF12 MAP1B GPS2 A2ML1 QSER1 PBX2 TRRAP HSP90AB1	4.85e-05	857	69	9	25609649
Pubmed	Junctional Epidermolysis Bullosa	COL17A1 ITGB4	5.79e-05	6	69	2	20301304
Pubmed	PRISMA and BioID disclose a motifs-based interactome of the intrinsically disordered transcription factor C/EBPα.	CCNT2 TCF12 TCF20 GPS2 SNRNP40 UPF1 QSER1 TRRAP ZNF281 MED12	6.15e-05	1103	69	10	34189442
Pubmed	Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.	TCF20 MAP1B A2ML1 SNRNP40 PDCD11 UPF1 CDC5L TRRAP ZNF281 MED12 HSP90AB1	6.81e-05	1353	69	11	29467282
Pubmed	Interaction network of human early embryonic transcription factors.	TCF20 GPS2 QSER1 PBX2 ZNF281 MED12	7.11e-05	351	69	6	38297188
Pubmed	MKRN2 Physically Interacts with GLE1 to Regulate mRNA Export and Zebrafish Retinal Development.	MAP1B PLAG1 DLX2 UPF1 CDC5L DSCAML1	7.92e-05	358	69	6	32460013
Pubmed	NMD abnormalities during brain development in the Fmr1-knockout mouse model of fragile X syndrome.	MAP1B UPF1	8.09e-05	7	69	2	34784943
Pubmed	The N terminus of the transmembrane protein BP180 interacts with the N-terminal domain of BP230, thereby mediating keratin cytoskeleton anchorage to the cell surface at the site of the hemidesmosome.	COL17A1 ITGB4	8.09e-05	7	69	2	10637308
Pubmed	Parcellation of the striatal complex into dorsal and ventral districts.	ETV1 ASTN2 DLX2	8.12e-05	42	69	3	32170006
Pubmed	Comprehensive Interactome Mapping of the DNA Repair Scaffold SLX4 Using Proximity Labeling and Affinity Purification.	TCF20 PDCD11 POLQ ZNF281 AFF4	8.17e-05	222	69	5	37071664
Pubmed	Peripheral NT3 signaling is required for ETS protein expression and central patterning of proprioceptive sensory afferents.	EGR3 ETV1	1.08e-04	8	69	2	12741988
Pubmed	Gene regulatory logic of dopamine neuron differentiation.	ETV1 DLX2	1.08e-04	8	69	2	19287374
Pubmed	Expression patterns of the three Teashirt-related genes define specific boundaries in the developing and postnatal mouse forebrain.	ETV1 DLX2	1.08e-04	8	69	2	15834955
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	PTPN9 TCF20 GRIK5 UPF1 QSER1 CDC5L TNR AFF4 HSP90AB1	1.18e-04	963	69	9	28671696
Pubmed	Dlx1&2 and Mash1 transcription factors control MGE and CGE patterning and differentiation through parallel and overlapping pathways.	FOXO3 EGR3 ETV1 DLX2	1.33e-04	130	69	4	19386638
Pubmed	Analysis of the interactions between BP180, BP230, plectin and the integrin alpha6beta4 important for hemidesmosome assembly.	COL17A1 ITGB4	1.38e-04	9	69	2	12482924
Pubmed	SLFN11 promotes CDT1 degradation by CUL4 in response to replicative DNA damage, while its absence leads to synthetic lethality with ATR/CHK1 inhibitors.	MAP1B SNRNP40 CDC5L POLQ TRRAP	1.42e-04	250	69	5	33536335
Pubmed	Nuclear import of histone deacetylase 5 by requisite nuclear localization signal phosphorylation.	MAP1B GPS2 UPF1 CDC5L HSP90AB1	1.65e-04	258	69	5	21081666
Pubmed	AGAP1/AP-3-dependent endocytic recycling of M5 muscarinic receptors promotes dopamine release.	CHRM5 AGAP1	1.73e-04	10	69	2	20664521
Pubmed	Generation of GABAergic and dopaminergic interneurons from endogenous embryonic olfactory bulb precursor cells.	ETV1 DLX2	1.73e-04	10	69	2	17038521
Pubmed	Identification of two distinct progenitor populations in the lateral ganglionic eminence: implications for striatal and olfactory bulb neurogenesis.	ETV1 DLX2	1.73e-04	10	69	2	12514213
Pubmed	The caudal ganglionic eminence is a source of distinct cortical and subcortical cell populations.	ETV1 DLX2	1.73e-04	10	69	2	12411960
Pubmed	A deep proteomics perspective on CRM1-mediated nuclear export and nucleocytoplasmic partitioning.	FOXO3 TCF12 SEC24A GPS2 SNRNP40 UPF1 MED12 DENND4C AGAP1	2.07e-04	1038	69	9	26673895
Pubmed	Genetic regulation of mouse stem cells: identification of two keratinocyte stem cell regulatory loci.	BMP5 TCF12	2.11e-04	11	69	2	14594209
Pubmed	Beta4 integrin is required for hemidesmosome formation, cell adhesion and cell survival.	COL17A1 ITGB4	2.11e-04	11	69	2	8707838
Pubmed	Thy1 marks a distinct population of slow-cycling stem cells in the mouse epidermis.	COL17A1 ITGB4	2.11e-04	11	69	2	35941116
Pubmed	Interaction of the bullous pemphigoid antigen 1 (BP230) and desmoplakin with intermediate filaments is mediated by distinct sequences within their COOH terminus.	COL17A1 ITGB4	2.11e-04	11	69	2	12802069
Pubmed	Whole exome sequencing identifies novel recurrently mutated genes in patients with splenic marginal zone lymphoma.	TRRAP USH2A	2.11e-04	11	69	2	24349473
Pubmed	The tetraspan molecule CD151, a novel constituent of hemidesmosomes, associates with the integrin alpha6beta4 and may regulate the spatial organization of hemidesmosomes.	COL17A1 ITGB4	2.11e-04	11	69	2	10811835
Pubmed	Current insights into the formation and breakdown of hemidesmosomes.	COL17A1 ITGB4	2.11e-04	11	69	2	16757171
Pubmed	Interlaboratory reproducibility of large-scale human protein-complex analysis by standardized AP-MS.	CCNT2 MAP1B TAOK1 CDC5L AFF4 HSP90AB1	2.20e-04	432	69	6	23455922
Pubmed	ETS gene Er81 controls the formation of functional connections between group Ia sensory afferents and motor neurons.	EGR3 ETV1	2.53e-04	12	69	2	10850491
Pubmed	Molecular and genetic characterization of GABP beta.	POU1F1 SI	2.53e-04	12	69	2	7958862
Pubmed	Identification of two keratinocyte stem cell regulatory loci implicated in skin carcinogenesis.	BMP5 TCF12	2.53e-04	12	69	2	12663500
Pubmed	Scapula development is governed by genetic interactions of Pbx1 with its family members and with Emx2 via their cooperative control of Alx1.	TBX15 PBX2	2.53e-04	12	69	2	20627960
Pubmed	Identification of proximal SUMO-dependent interactors using SUMO-ID.	TCF12 MAP1B UPF1 CDC5L ZNF281 HSP90AB1	2.54e-04	444	69	6	34795231
Pubmed	SENP3 regulates the global protein turnover and the Sp1 level via antagonizing SUMO2/3-targeted ubiquitination and degradation.	CDC5L TRRAP HSP90AB1	2.86e-04	64	69	3	26511642
Pubmed	Plag1 and Plagl2 have overlapping and distinct functions in telencephalic development.	ETV1 PLAG1	2.98e-04	13	69	2	30361413
Pubmed	Cell cycle and adhesion defects in mice carrying a targeted deletion of the integrin beta4 cytoplasmic domain.	COL17A1 ITGB4	2.98e-04	13	69	2	9670011
Pubmed	A yeast two-hybrid screen reveals that osteopontin associates with MAP1A and MAP1B in addition to other proteins linked to microtubule stability, apoptosis and protein degradation in the human brain.	MAP1B RIMS4 AFF4	3.41e-04	68	69	3	22779921
Pubmed	Control of pelvic girdle development by genes of the Pbx family and Emx2.	TBX15 PBX2	3.48e-04	14	69	2	21455939
Pubmed	MLL-AF9 and MLL-ENL alter the dynamic association of transcriptional regulators with genes critical for leukemia.	CCNT2 AFF4	3.48e-04	14	69	2	20854876
Pubmed	PRC1 preserves epidermal tissue integrity independently of PRC2.	COL17A1 ITGB4	3.48e-04	14	69	2	30567998
Pubmed	Removal of Pax6 partially rescues the loss of ventral structures in Shh null mice.	ETV1 DLX2	3.48e-04	14	69	2	16766714
Pubmed	Differential regulation of telencephalic pallial-subpallial boundary patterning by Pax6 and Gsh2.	ETV1 DLX2	3.48e-04	14	69	2	18701439
Pubmed	Dynamic expression of MEIS1 homeoprotein in E14.5 forebrain and differentiated forebrain-derived neural stem cells.	DLX2 PBX2	4.01e-04	15	69	2	23756022
Pubmed	Identification of markers of the midface.	TBX15 DLX2	4.01e-04	15	69	2	15615879
Pubmed	Cooperative activity of cdk8 and GCN5L within Mediator directs tandem phosphoacetylation of histone H3.	TRRAP MED12	4.01e-04	15	69	2	18418385
Pubmed	Human mediator subunit MED26 functions as a docking site for transcription elongation factors.	CCNT2 MED12 AFF4	4.21e-04	73	69	3	21729782
Pubmed	The HIV-1 Tat protein recruits a ubiquitin ligase to reorganize the 7SK snRNP for transcriptional activation.	CCNT2 GTF2IRD2B CLCN3 GTF2IRD2 PDCD11 POLDIP2 CDC5L POLQ HSP90AB1	4.46e-04	1153	69	9	29845934
Pubmed	The protein interaction landscape of the human CMGC kinase group.	CCNT2 RIMS4 SNRNP40 PDCD11 ZNF281 MED12 AFF4	4.55e-04	695	69	7	23602568
Pubmed	Delineation of multiple subpallial progenitor domains by the combinatorial expression of transcriptional codes.	ETV1 DLX2	4.57e-04	16	69	2	17804629
Pubmed	Impaired plasma membrane localization of ubiquitin ligase complex underlies 3-M syndrome development.	PRUNE2 SNRNP40 CHIT1 POLQ AFF4 DNAH1	4.58e-04	496	69	6	31343991
Pubmed	Destabilization of Atoh1 by E3 Ubiquitin Ligase Huwe1 and Casein Kinase 1 Is Essential for Normal Sensory Hair Cell Development.	TCF12 MAP1B TRRAP	4.74e-04	76	69	3	27542412
Pubmed	Dlx-dependent and -independent regulation of olfactory bulb interneuron differentiation.	ETV1 DLX2	5.18e-04	17	69	2	17376983
Pubmed	The bromodomain protein Brd4 is a positive regulatory component of P-TEFb and stimulates RNA polymerase II-dependent transcription.	CCNT2 MED12	5.18e-04	17	69	2	16109376
Pubmed	MOF-mediated histone H4 Lysine 16 acetylation governs mitochondrial and ciliary functions by controlling gene promoters.	COL17A1 ITGB4	5.18e-04	17	69	2	37479688
Pubmed	The AERO system: a 3D-like approach for recording gene expression patterns in the whole mouse embryo.	TBX15 DLX2 PBX2 HSP90AB1	5.77e-04	191	69	4	24146773
Pubmed	Menin and Menin-Associated Proteins Coregulate Cancer Energy Metabolism.	TCF20 TRRAP ZNF281 MED12 AFF4	5.92e-04	341	69	5	32971831
Pubmed	The Nse5/6-like SIMC1-SLF2 complex localizes SMC5/6 to viral replication centers.	TCF20 MAP1B PDCD11 QSER1 CDC5L ZNF281 AFF4 HSP90AB1	5.93e-04	954	69	8	36373674
Pubmed	Cdh1-APC Regulates Protein Synthesis and Stress Granules in Neurons through an FMRP-Dependent Mechanism.	MAP1B UPF1 CDC5L HSP90AB1	6.47e-04	197	69	4	32434143
Pubmed	Loss of Nkx2.1 homeobox gene function results in a ventral to dorsal molecular respecification within the basal telencephalon: evidence for a transformation of the pallidum into the striatum.	ETV1 DLX2	6.49e-04	19	69	2	10393115
Pubmed	Transcriptional fates of human-specific segmental duplications in brain.	GTF2IRD2B GTF2IRD2	6.49e-04	19	69	2	30228200
Pubmed	ETO2 coordinates cellular proliferation and differentiation during erythropoiesis.	TCF12 TRRAP	7.20e-04	20	69	2	16407974
Pubmed	Inactivation of Arx, the murine ortholog of the X-linked lissencephaly with ambiguous genitalia gene, leads to severe disorganization of the ventral telencephalon with impaired neuronal migration and differentiation.	ETV1 DLX2	7.20e-04	20	69	2	17460091
Pubmed	The E3 ubiquitin ligase HECTD1 contributes to cell proliferation through an effect on mitosis.	MAP1B SNRNP40 PDCD11 UPF1 CDC5L TRRAP MED12	7.66e-04	759	69	7	35915203
Pubmed	Temporal requirement for hedgehog signaling in ventral telencephalic patterning.	ETV1 DLX2	7.95e-04	21	69	2	15371303
Cytoband	17q11.2	TAOK1 POLDIP2 RAB11FIP4	6.25e-04	110	69	3	17q11.2
Cytoband	3p21.1	ALAS1 DNAH1	1.84e-03	42	69	2	3p21.1
Cytoband	Ensembl 112 genes in cytogenetic band chr17q11	TAOK1 POLDIP2 RAB11FIP4	2.22e-03	171	69	3	chr17q11
GeneFamily	Fibronectin type III domain containing	ASTN2 TNR USH2A ITGB4 DSCAML1	1.14e-04	160	54	5	555
Coexpression	GSE13306_TREG_VS_TCONV_SPLEEN_UP	ELAPOR2 PTPN9 MAP1B SEC24A ASTN2 DSCAML1	1.47e-05	200	69	6	M3224
Coexpression	GSE5589_LPS_AND_IL10_VS_LPS_AND_IL6_STIM_MACROPHAGE_45MIN_UP	FOXO3 TCF12 GPS2 ETV1 DENND4C AFF4	1.47e-05	200	69	6	M6613
ToppCell	TCGA-Adrenal-Primary_Tumor-Pheochromocytoma-Pheochromocytoma-1\|TCGA-Adrenal / Sample_Type by Project: Shred V9	PRUNE2 NEBL EGR3 ASTN2 DLX2 TNR	3.55e-07	179	69	6	431e1b29015ec817f778499106d24b19cfc825ae
ToppCell	3'-Adult-Distal_Rectal-Epithelial-Tuft-related-Microfold_cell\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	TCF12 COL17A1 VNN2 ZDHHC14 CHRM5	7.72e-06	175	69	5	8a37b2811f39bb9baa537e8755a29d559eb8185a
ToppCell	3'-Adult-Distal_Rectal-Epithelial-Tuft-related\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	TCF12 COL17A1 VNN2 ZDHHC14 CHRM5	8.39e-06	178	69	5	a95bb77a2c2ce7c38989e6f971812f7ee9f5bd4b
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PRUNE2 NEBL ZDHHC14 ASTN2 DSCAML1	9.59e-06	183	69	5	738e94b50c4c08c727d4eed0708dda08aa6891b4
ToppCell	COVID-19-kidney-PCT-S1\|kidney / Disease (COVID-19 only), tissue and cell type	PRUNE2 SLC13A1 NEBL ASTN2 DSCAML1	9.85e-06	184	69	5	51ed1ebfdef45149541917c66cbacad87072e51f
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	PRUNE2 NEBL ZDHHC14 ASTN2 DSCAML1	1.04e-05	186	69	5	f0c8de4f6ae9047b9108a47a2af8c5f42bc103b0
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Degenerative_Descending_Thin_Limb_Cell_Type_3\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	PRUNE2 NEBL ZDHHC14 ASTN2 DSCAML1	1.06e-05	187	69	5	c31130fc2f9f882944b2ba366a034a03f051c4b9
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	PRUNE2 NEBL ZDHHC14 ASTN2 DSCAML1	1.09e-05	188	69	5	af740fa78542438fdff627ea1f74f4eee43316be
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	PRUNE2 NEBL ZDHHC14 ASTN2 DSCAML1	1.09e-05	188	69	5	63a4b25a0a6e05f80f1a6dd91b817f3cf49e6b68
ToppCell	Children_(3_yrs)-Endothelial-endothelial_cell_of_lymph_vessel\|Children_(3_yrs) / Lineage, Cell type, age group and donor	ADAM19 MAP1B ZDHHC14 DNAJC18 DSCAML1	1.09e-05	188	69	5	c2805232618a7b6f844d34e37ad458a9923dbfe1
ToppCell	Children_(3_yrs)-Endothelial-endothelial_cell_of_lymph_vessel-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	ADAM19 MAP1B ZDHHC14 DNAJC18 DSCAML1	1.09e-05	188	69	5	aeecbc057dc823f8fcea8a98f18d213bacc7f4db
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	PRUNE2 NEBL ZDHHC14 ASTN2 DSCAML1	1.12e-05	189	69	5	904b8337e2cabac2f0bf5dad5598fc429581ed81
ToppCell	COVID-19-kidney-PCT-S2\|kidney / Disease (COVID-19 only), tissue and cell type	PRUNE2 SLC13A1 ASTN2 DSCAML1 AGAP1	1.12e-05	189	69	5	0be5c669b6b308bd98ddb70c84877c62a6244bbd
ToppCell	Bronchial-NucSeq-Stromal-Myofibroblastic-Muscle_perivascular_immune_recruiting\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	TBX15 PRUNE2 ADAM19 MAP1B GRIK5	1.37e-05	197	69	5	cfb3dc4b401800e33c82cfc3baee69dbbd16ac8c
ToppCell	distal-1-Epithelial-Basal\|1 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	COL17A1 A2ML1 DLX2 TNS4 ITGB4	1.37e-05	197	69	5	25a2ccc98b973611de0d920b1b455d0b40f0d37f
ToppCell	distal-Epithelial-Basal-1\|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	COL17A1 A2ML1 DLX2 TNS4 ITGB4	1.37e-05	197	69	5	75b4292ce2ad7f9c8b6a4781e1cb71f5b18b74e3
ToppCell	PBMC-Mild-Myeloid-Neutrophil-immature_Neutrophil-Neu_4\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	BMP5 COL17A1 A2ML1 CHIT1	4.40e-05	126	69	4	6cb89754010d64875e115da6c5805efac7a4a82d
ToppCell	PBMC-Mild-Myeloid-Neutrophil-immature_Neutrophil-Neu_4\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	BMP5 COL17A1 A2ML1 CHIT1	4.40e-05	126	69	4	69b2525b92d1c7c35b21cc701f5fa52a9c1b94bb
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_1\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PRUNE2 ASTN2 GRIK5 DSCAML1	5.76e-05	135	69	4	8521107817df49efd9a2e81078c8535ed33e729c
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_ascending_limb_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	PRUNE2 NEBL ASTN2 DSCAML1	6.28e-05	138	69	4	a88c3ae56b0af60f6e87cabade4f21e2bbb336f2
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-Degenerative_Endothelial_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	COL17A1 MUC16 TNS4 CHRM5	1.06e-04	158	69	4	0c3907e3395ed01b3fd7b75fdca6feadc890ea85
ToppCell	Healthy_Control-Lymphoid-B-\|Healthy_Control / Condition, Lineage, Cell class and cell subclass	ELAPOR2 ADAM19 MAP1B ITGB4	1.19e-04	163	69	4	d84bd41b4494c7d5c7f88d511bfe481fb12f079d
ToppCell	Healthy_Control-Lymphoid-B\|Healthy_Control / Condition, Lineage, Cell class and cell subclass	ELAPOR2 ADAM19 MAP1B ITGB4	1.19e-04	163	69	4	0f723ec2503afa1b3ebb0754972438ffb6e6179d
ToppCell	facs-Marrow-KLS-18m-Lymphocytic-BM_CD4_T_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRUNE2 BMP5 COL17A1 NEBL	1.28e-04	166	69	4	aa2df07eff323ded751ced8938af08223d7f2029
ToppCell	facs-Marrow-KLS-18m-Lymphocytic-CD4-positive,_alpha-beta_T_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRUNE2 BMP5 COL17A1 NEBL	1.28e-04	166	69	4	695298a94d62b8adab083900003ec636fbaae5d9
ToppCell	ASK440-Epithelial-Transformed_epithelium\|ASK440 / Donor, Lineage and Cell class of Lung cells from Dropseq	NEBL ZDHHC14 UPF1 POLQ	1.47e-04	172	69	4	df3800bcd9777d02900eba0cfc26ab73de8a1d95
ToppCell	normal_Lymph_Node-Myeloid_cells-pDCs\|Myeloid_cells / Location, Cell class and cell subclass	CCNT2 GTF2IRD2B ADAM19 CLCN3	1.54e-04	174	69	4	2274648b80dd74f3c948a779bba3391095964c34
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	PRUNE2 NEBL ZDHHC14 DSCAML1	1.60e-04	176	69	4	327a3e81b724252e36d786de92a3ffd721ea6d7b
ToppCell	Nasal_Brush-Epithelial-Basal_2\|Nasal_Brush / Tissue, Lineage and Cell class of Lung Cells from 10X	BMP5 COL17A1 EGR3 TNS4	1.60e-04	176	69	4	fc5787946f5a10056d326d070620575ae4081836
ToppCell	Nasal_Brush-Epithelial-Basal_2\|Epithelial / Tissue, Lineage and Cell class of Lung Cells from 10X	BMP5 COL17A1 EGR3 TNS4	1.60e-04	176	69	4	5daaba0853afe7d20d4635169ccd4f96e735b938
ToppCell	Adult-Endothelial-endothelial_cell_of_lymph_vessel-D231\|Adult / Lineage, Cell type, age group and donor	ADAM19 ZDHHC14 DNAJC18 DSCAML1	1.68e-04	178	69	4	c80ca7a2d3f976089a5e71d0cd9ba9a1c0bd2815
ToppCell	COVID-19-kidney-tDL\|COVID-19 / Disease (COVID-19 only), tissue and cell type	PRUNE2 SLC13A1 ASTN2 DSCAML1	1.75e-04	180	69	4	864c895b5eaedefae86f5829fa344f7b686fb59f
ToppCell	COVID-19-kidney-PCT-S2\|COVID-19 / Disease (COVID-19 only), tissue and cell type	PRUNE2 SLC13A1 ASTN2 DSCAML1	1.75e-04	180	69	4	358923e4228035a3e90e2957392089219e90dcd7
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PRUNE2 NEBL ASTN2 DSCAML1	1.79e-04	181	69	4	9d782ba5cf5a172cb4f447763fc50e5b13ef7dd9
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	NEBL ZDHHC14 ASTN2 DSCAML1	1.79e-04	181	69	4	6a6bd8e020cb0929b6ecdcb55d467ad24fecfaf0
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_1\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	NEBL ZDHHC14 ASTN2 DSCAML1	1.79e-04	181	69	4	071f9bb5d39070cdc473d9b0e094d196bc702b56
ToppCell	3'-GW_trimst-1.5-SmallIntestine-Neuronal-neurons_A-Branch_A4_(IN)\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	MAP1B RIMS4 ETV1 GRIK5	1.82e-04	182	69	4	be32b5b8153c1053cbb55f1fccfa27c3ee97c1e1
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_3\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PRUNE2 NEBL ASTN2 DSCAML1	1.82e-04	182	69	4	eb138aa1dca9373f1586600f258df06dcf56d81f
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	PRUNE2 NEBL ZDHHC14 DSCAML1	1.82e-04	182	69	4	5e1b316599436740f1b30875f0ebd33c3edfb2b6
ToppCell	COVID-19-kidney-Distal_Epi_Doublet_(PCT)\|COVID-19 / Disease (COVID-19 only), tissue and cell type	PRUNE2 SLC13A1 ASTN2 DSCAML1	1.82e-04	182	69	4	9d67717a6e13bcb54c1297a3e4e3abf4e51628a3
ToppCell	343B-Lymphocytic-CD4_T-cell-Treg_cell_1\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	MDFIC TAOK1 ALAS1 TRRAP	1.86e-04	183	69	4	807d64deaf4e50dccf6f831f88578a6d903c1421
ToppCell	Basal\|World / shred by cell class for mouse tongue	COL17A1 MAP1B TNS4 ITGB4	1.86e-04	183	69	4	c6729a207526ff4aa48176207b9353176f631fea
ToppCell	facs-Lung-24m-Hematologic-myeloid-non-classical_monocyte-nonclassical_monocyte_l14\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	COL17A1 MAP1B RAB11FIP4 ITGB4	1.86e-04	183	69	4	6e5b39c0170d62eb7fdd411dcfff51ed176573d0
ToppCell	COVID-19-kidney-PCT-S1\|COVID-19 / Disease (COVID-19 only), tissue and cell type	PRUNE2 SLC13A1 ASTN2 DSCAML1	1.86e-04	183	69	4	6878d14026c3df6aa12e45dfad94b32fa9d9b0b7
ToppCell	Control-Epithelial_cells-Airway_mucous\|Control / group, cell type (main and fine annotations)	COL17A1 MUC16 ITGB4 AGAP1	1.86e-04	183	69	4	15d24a4fb1ffe6cbafbd54fcd7dde9ddcfbe03b2
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PRUNE2 NEBL ASTN2 DSCAML1	1.86e-04	183	69	4	92fbd83a9d13ee91065cbd479fb298f1fd564568
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_1\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	NEBL ZDHHC14 ASTN2 DSCAML1	1.90e-04	184	69	4	da06ff24ee2b2cf4715fdfce43030b2da9e0aaf8
ToppCell	cellseq-Epithelial-Epithelial_Glandular-MEC\|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	COL17A1 MAP1B TNS4 ITGB4	1.94e-04	185	69	4	0595e7ab37eed690f6e3d16a9a4e9a4bce2b89db
ToppCell	COVID-19-kidney-Mito-rich_PCT\|COVID-19 / Disease (COVID-19 only), tissue and cell type	PRUNE2 SLC13A1 ASTN2 DSCAML1	1.94e-04	185	69	4	1bbc2ba8a20f72f61981b1301cdd6018cdd9150d
ToppCell	cellseq-Epithelial-Epithelial_Glandular-MEC-MEC\|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	COL17A1 MAP1B TNS4 ITGB4	1.94e-04	185	69	4	76304829fcfb5934188933ca20d33bc8c8b0dc91
ToppCell	facs-Pancreas-Endocrine-3m-Epithelial-pancreatic_acinar_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FOXO3 BMP5 DSCAML1	1.99e-04	73	69	3	1bd6ff9659efc43b0a596da50e325bde2f0ba8f7
ToppCell	facs-Pancreas-Endocrine-3m-Epithelial-pancreatic_acinar_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FOXO3 BMP5 DSCAML1	1.99e-04	73	69	3	3ac392ac46ad577c7d2c2b5e6a0a96ceb613097b
ToppCell	COVID-19-kidney-tDL\|kidney / Disease (COVID-19 only), tissue and cell type	PRUNE2 SLC13A1 ASTN2 AGAP1	2.02e-04	187	69	4	d35d27ca3c0e65f92f4508e1cb98a743f44fdcdf
ToppCell	COVID-19-kidney\|COVID-19 / Disease (COVID-19 only), tissue and cell type	PRUNE2 SLC13A1 ASTN2 DSCAML1	2.02e-04	187	69	4	d23aae9419d460b78b1d4092d7acd9108a47cfbe
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PRUNE2 NEBL ASTN2 DSCAML1	2.02e-04	187	69	4	c41a2c81dd2ceef303f39f699032aa7d6ea67cf0
ToppCell	COVID-19-kidney-Mito-rich_PCT\|kidney / Disease (COVID-19 only), tissue and cell type	PRUNE2 SLC13A1 ASTN2 DSCAML1	2.02e-04	187	69	4	738ec2611b4be6a08eedad16b57fba84e1f11fef
ToppCell	Endothelial-endothelial_cell_of_lymph_vessel\|World / Lineage, Cell type, age group and donor	ADAM19 MAP1B ZDHHC14 DNAJC18	2.06e-04	188	69	4	80910dcbb51990f2baed240f319456c0d3fa2065
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_ascending_limb_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PRUNE2 NEBL ASTN2 DSCAML1	2.15e-04	190	69	4	1cf023e3c6924d6a06f353d4b62444b6f2fee8a7
ToppCell	PND10\|World / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ADAM19 MAP1B ETV1 AFF4	2.15e-04	190	69	4	d67e2814047c8df2ae4b7bc8be9539f5df6ecef2
ToppCell	PBMC-Severe-Myeloid-Neutrophil\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	COL17A1 EGR3 VNN2 CHIT1	2.15e-04	190	69	4	cb62ece5929896dfba30a4f563c6ba5a5712b71e
ToppCell	PBMC-Severe-Myeloid-Neutrophil\|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)	COL17A1 EGR3 VNN2 CHIT1	2.15e-04	190	69	4	fedd266198d294d8da8c9e217e5e0cb8b2e1b566
ToppCell	Children_(3_yrs)-Endothelial-endothelial_cell_of_lymph_vessel-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	ZDHHC14 DNAJC18 ITGB4 DSCAML1	2.15e-04	190	69	4	6e6ce6dd549d1c38cfef5b3f8be06ab01ce344b7
ToppCell	COVID-19_Severe-Myeloid_G\|COVID-19_Severe / Disease group, lineage and cell class	COL17A1 EGR3 VNN2 CHIT1	2.15e-04	190	69	4	8a81cb90273c361e9fdfaa0a31806da253fa1388
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_ascending_limb_epithelial_cell-Ascending_Thin_Limb_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PRUNE2 NEBL ASTN2 DSCAML1	2.15e-04	190	69	4	59bbbd2c8d4b7ce46c54ca8022b1557e7e5eee2a
ToppCell	facs-Pancreas-Endocrine-3m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRUNE2 ELAPOR2 MAP1B DENND4C	2.19e-04	191	69	4	f76f3f5c7902a3659d8cbe470f96ce57c8a6744d
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	NEBL ZDHHC14 ASTN2 DSCAML1	2.19e-04	191	69	4	d0e9afe7b6334dd515d3e68892efdc76347a55e5
ToppCell	facs-Skin\|facs / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL17A1 TNS4 CHIT1 ITGB4	2.19e-04	191	69	4	ae524103331fa53fa82888dbb567fc36abcee7e0
ToppCell	PCW_05-06-Mesenchymal-Mesenchymal_myocytic-mes_immature_ASM1_(8)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	BMP5 CLCN3 NEBL ETV1	2.28e-04	193	69	4	e2b455387d1de7812305200a2041a0f4759a6f54
ToppCell	Fetal_29-31_weeks-Mesenchymal-matrix_fibroblast_1_cell-D062\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	BMP5 NEBL ZDHHC14 ETV1	2.33e-04	194	69	4	35f132cc38ac133be01834ed0946188aa0757eb4
ToppCell	RA-03._Atrial_Cardiomyocyte\|World / Chamber and Cluster_Paper	PRUNE2 ADAM19 NEBL ASTN2	2.33e-04	194	69	4	89812fb164065041357bb37a3c2d87028ec3de4e
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	PRUNE2 NEBL ASTN2 AGAP1	2.33e-04	194	69	4	7002937e8903e037332a215d00fbc7c7843b33f2
ToppCell	Bronchial-NucSeq-Immune_Lymphocytic-B-B_cell-B_mature\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	ADAM19 ZDHHC14 CHIT1 TNR	2.37e-04	195	69	4	3311a1bf4ed94820b45047d44fc14b14ac72e6fb
ToppCell	PCW_10-12-Mesenchymal-Mesenchymal_fibroblastic-mes_immature5_(6)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	BMP5 NEBL ZDHHC14 ETV1	2.37e-04	195	69	4	0e55fa5b3cbeb7baee3d4ac272a3bf80381ec937
ToppCell	facs-Tongue\|facs / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL17A1 TNS4 CHIT1 ITGB4	2.37e-04	195	69	4	77128895db9221a64a171082d468ebcd6380c936
ToppCell	Bronchial-NucSeq-Epithelial-Epi_submucosal-gland-Myoepithelial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	COL17A1 MAP1B TNS4 ITGB4	2.42e-04	196	69	4	a58bdf9de05d13d84211e09a933679d485bf8ab4
ToppCell	droplet-Tongue-nan-3m-Epithelial-suprabasal_differentiating\|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL17A1 DLX2 TNS4 HSP90AB1	2.42e-04	196	69	4	27364b577d77aefaa147abb346c46fce61e28ec3
ToppCell	Bronchial-NucSeq-Immune_Lymphocytic-B-B_cell\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	ADAM19 ZDHHC14 CHIT1 TNR	2.47e-04	197	69	4	da61afba697ec49ca86e062d35a825280da558ac
ToppCell	Parenchymal-NucSeq-Stromal-Myofibroblastic-Muscle_perivascular_immune_recruiting\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	PRUNE2 ADAM19 MAP1B EGR3	2.47e-04	197	69	4	3332b9b5bf78f0203ebbd94257a36e9054d896c3
ToppCell	Bronchial-NucSeq-Stromal-Myofibroblastic-Muscle_smooth_pulmonary\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	PRUNE2 ADAM19 MAP1B GRIK5	2.47e-04	197	69	4	bf0520a94ebb1d2f94de9f526d17e0b0e8fe7052
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	PRUNE2 NEBL ASTN2 DSCAML1	2.47e-04	197	69	4	7e93a97b5ac5ae2f77a4b3141082a1463fed00dd
ToppCell	Parenchymal-NucSeq-Stromal-Myofibroblastic-Muscle_smooth_airway_ASM\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	PRUNE2 PCYOX1L ADAM19 GRIK5	2.52e-04	198	69	4	d1827e3707b929e3a3562989a0c11537d344e164
ToppCell	Tracheal-NucSeq-Stromal-Myofibroblastic\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	PRUNE2 ADAM19 MAP1B GRIK5	2.52e-04	198	69	4	c12e7511628db819a52959bb68580e27c00c2e41
ToppCell	Tracheal-10x5prime-Stromal-Myofibroblastic-Muscle_smooth_airway_ASM\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	PRUNE2 ELAPOR2 MAP1B GRIK5	2.52e-04	198	69	4	1e1ea54f0c234f3b6d29064c4881d8a0c0949a75
ToppCell	Parenchymal-NucSeq-Immune_Lymphocytic-B-B_cell-B_mature\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	ADAM19 ZDHHC14 CHIT1 TNR	2.52e-04	198	69	4	4aa4ae2571effcfb6eb6923f7173cd3e7e4af9ef
ToppCell	Bronchial_Biopsy\|World / Tissue, Lineage and Cell class of Lung Cells from 10X	COL17A1 EGR3 TNS4 ITGB4	2.52e-04	198	69	4	f5b7013045b61fc56894f80092f799770dde1c8f
ToppCell	Parenchyma_Control_(B.)-Epithelial-TX-Basal_2\|Parenchyma_Control_(B.) / Sample group, Lineage and Cell type	COL17A1 MUC16 DLX2 TNS4	2.52e-04	198	69	4	686eda427b075e788de38149eae82faf19bd5704
ToppCell	Lung_Parenchyma-Control-Epithelial-Epithelial-Basal_2-\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	COL17A1 MUC16 DLX2 TNS4	2.52e-04	198	69	4	a54ae5275a510b49d7629f0908817a0c5f05020e
ToppCell	Lung_Parenchyma-Control-Epithelial-Epithelial-Basal_2\|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)	COL17A1 MUC16 DLX2 TNS4	2.52e-04	198	69	4	34997e3896d0893fbe51bfb0d4660ccaca1c975e
ToppCell	facs-Tongue-nan-3m-Epithelial-basal_cell_of_epidermis\|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL17A1 TCF20 TAOK1 ITGB4	2.52e-04	198	69	4	22559b161e67b49fe8028bfaf861e069063599f5
ToppCell	Bronchial-10x5prime-Stromal-Peri/Epineurial_\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	TBX15 MAP1B ETV1 ITGB4	2.56e-04	199	69	4	45c3b853900d8c3d5965117d904e3714100138bc
ToppCell	(02)_MMP9/10+\|World / shred by cell type by condition	ADAM19 COL17A1 TNS4 ITGB4	2.56e-04	199	69	4	3f78eddeaa67d3b767aa38de765632166b09a4f0
ToppCell	3'-Broncho-tracheal-Epithelial-Airway_epithelium-respiratory_basal_cell-Basal_resting\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	COL17A1 TNS4 ITGB4 HSP90AB1	2.56e-04	199	69	4	a60880d6b73b2f33b33790873b8c1e8096863908
ToppCell	10x_3'_v2v3-Neoplastic-Stem-like\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	TCF12 MAP1B ETV1 TNR	2.56e-04	199	69	4	94baf00dad27964392c3fc34970a4e79d576d0d3
ToppCell	Bronchial-10x5prime-Epithelial-Epi_airway_basal\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	COL17A1 EGR3 TNS4 ITGB4	2.61e-04	200	69	4	afac850d5a40de0d6f02857cf81a19443d90b1eb
ToppCell	Lung_Parenchyma-Severe-Epithelial-Epithelial-Basal_3-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	COL17A1 EGR3 TNS4 ITGB4	2.61e-04	200	69	4	41705bbba40eb5ddca0b223191aac1bce00163b8
ToppCell	Lung_Parenchyma-Severe-Epithelial-Epithelial-Basal_3\|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)	COL17A1 EGR3 TNS4 ITGB4	2.61e-04	200	69	4	cc8df398532c9324fd3e171000b1ea5c208cd691
ToppCell	Bronchial-NucSeq-Stromal-Myofibroblastic\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	PRUNE2 ADAM19 MAP1B GRIK5	2.61e-04	200	69	4	a66449b22b39dd6987fc2c3ed160d24564234ced
ToppCell	Bronchial-10x5prime-Stromal-Peri/Epineurial_-NAF_endoneurial\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	TBX15 MAP1B EGR3 ETV1	2.61e-04	200	69	4	29054cf55e88e1ac81a562d8dd9af9b7c749321d
ToppCell	Tracheal-10x5prime-Epithelial\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	COL17A1 MUC16 TNS4 ITGB4	2.61e-04	200	69	4	efd461c687155c84ef590352207e6fe4ba392a90
ToppCell	Parenchyma_COVID-19-Epithelial-TX-Basal_3\|Parenchyma_COVID-19 / Sample group, Lineage and Cell type	COL17A1 EGR3 TNS4 ITGB4	2.61e-04	200	69	4	53e04399d0308b40ae99fbfaa4ff62bf061822d8
Disease	Adult junctional epidermolysis bullosa (disorder)	COL17A1 ITGB4	4.91e-05	5	66	2	C0268374
Disease	EPIDERMOLYSIS BULLOSA, JUNCTIONAL, LOCALISATA VARIANT (disorder)	COL17A1 ITGB4	4.91e-05	5	66	2	C2608084
Disease	junctional epidermolysis bullosa non-Herlitz type (implicated_via_orthology)	COL17A1 ITGB4	4.91e-05	5	66	2	DOID:0060738 (implicated_via_orthology)
Disease	Junctional Epidermolysis Bullosa	COL17A1 ITGB4	7.35e-05	6	66	2	C0079301
Disease	dentate gyrus volume measurement	FOXO3 TRAF3IP2 ASTN2	9.22e-05	39	66	3	EFO_0010083
Disease	junctional epidermolysis bullosa (is_implicated_in)	COL17A1 ITGB4	1.03e-04	7	66	2	DOID:3209 (is_implicated_in)
Disease	cognitive inhibition measurement	TCF20 A2ML1 USH2A	1.94e-04	50	66	3	EFO_0007969
Disease	1,7-dimethylurate measurement	MDFIC GRIK5	2.19e-04	10	66	2	EFO_0021512
Disease	interleukin-6 measurement, response to stimulus	ELAPOR2 MUC16	2.68e-04	11	66	2	EFO_0004810, GO_0050896
Disease	Amelogenesis Imperfecta	COL17A1 ITGB4	3.21e-04	12	66	2	C0002452
Disease	autism spectrum disorder (implicated_via_orthology)	TCF20 RIMS4 TAOK1 DSCAML1	3.81e-04	152	66	4	DOID:0060041 (implicated_via_orthology)
Disease	Astrocytosis	TNR ITGB4	6.56e-04	17	66	2	C3887640
Disease	Gliosis	TNR ITGB4	6.56e-04	17	66	2	C0017639
Disease	amino acid measurement	CCNT2 PCYOX1L TCF12 DNAJC18 ASTN2 GRIK5 CHIT1	7.89e-04	678	66	7	EFO_0005134
Disease	temporal lobe epilepsy (is_marker_for)	FOXO3 GRIK5	9.12e-04	20	66	2	DOID:3328 (is_marker_for)
Disease	osteoarthritis, hip	BMP5 ASTN2 CDC5L	1.16e-03	92	66	3	EFO_1000786
Disease	obesity (implicated_via_orthology)	BMP5 TCF12 ETV1 MED12	1.39e-03	215	66	4	DOID:9970 (implicated_via_orthology)
Disease	alopecia	TBX15 TRAF3IP2 TCF12 CDC5L	2.10e-03	241	66	4	MONDO_0004907

Protein segments in the cluster

Peptide	Gene	Start	Entry
MGTYHNNMTTQSSSL	COL17A1	231	Q9UMD9
GPDANHEYSTSSQHM	CCNT2	696	O60583
GMSHGELSSEAYNQV	CDC5L	646	Q99459
DGMHQRSYSVSSADQ	AGAP1	466	Q9UPQ3
SVYQSGGVNMDHSEN	ADAM19	321	Q9H013
MEHANQQTGFSDSSS	GPS2	256	Q13227
IHTSYVGSRSSSNMA	A2ML1	1351	A8K2U0
DMHSTQIAASSTYHQ	DLX2	11	Q07687
LENGTLYFHVSMSSS	ASTN2	166	O75129
SSEHYSSQSHGNSMT	AFF4	271	Q9UHB7
DSSPTQNYISMHSSQ	QSER1	486	Q2KHR3
QLMHSSNFSSSNGST	RAB11FIP4	311	Q86YS3
GHTQTDYINASFMDG	PTPN9	351	P43378
YAFAGMTNHQLSTTE	CHIT1	56	Q13231
QYSSHVSLQASSGHM	POLDIP2	316	Q9Y2S7
HFSENTAETNMGTTN	MUC16	6006	Q8WXI7
TMTHSTISQGFSHSQ	MUC16	7931	Q8WXI7
THSTASQGFSHSQMT	MUC16	9106	Q8WXI7
YVNGFTHQSSMTTTR	MUC16	13436	Q8WXI7
RYHTSQSGDEMTSLS	HSP90AB1	456	P08238
SYSASQVESLRHSMG	PBX2	366	P40425
DTYSHMEGVASVSTA	MAP1B	1541	P46821
ATNSHFTHGEMQDQS	MDFIC	46	Q9P1T7
EIYSDSGNHASMIQG	ALAS1	331	P13196
YSLGESTFVNMTQHS	PCYOX1L	176	Q8NBM8
LSSYAVGFVHSSSQM	OR4K13	146	Q8NH42
SGENTNRAMSTCYSH	OR4M1	231	Q8NGD0
SGENTNRAMSTCYSH	OR4M2	231	Q8NGB6
YEHNTMVGSAASQSF	ETV1	236	P50549
STSHMSQSSSYGNLH	TCF12	256	Q99081
ATESGQTENSLHMGY	KRIT1	196	O00522
SVHQMTPSSSYGLQT	MED12	1926	Q93074
TTSGTLSTHMDQQFF	ITGB4	1806	P16144
HYDFSNLSSVGSLMN	ELAPOR2	686	A8MWY0
SSQGRPSSMYFQTHD	UPF1	961	Q92900
SSEQLSSQDHYDFGM	DNAH1	1741	Q9P2D7
SVQGYTQMLTHRSSD	C3P1	166	Q6ZMU1
DGSHRTNQYTMSDGT	DSCAML1	451	Q8TD84
TNQYTMSDGTTISHM	DSCAML1	456	Q8TD84
FSGSSDSVVHYNQMA	EGR3	36	Q06889
GGVASTSQDMHTYAA	POLQ	541	O75417
SDHGSSQNTSMSSIY	DENND4C	1466	Q5VZ89
SHQDSSRMSSVGDYN	BMP5	331	P22003
TGNIHMFSNVTDDTY	DNAJC18	186	Q9H819
QSGMYQLSSDVSHQE	HBP1	71	O60381
QTNIEYGTIHAGSTM	GRIK5	661	Q16478
YNMQGSHPSSTSNEV	GTF2IRD2	246	Q86UP8
YNMQGSHPSSTSNEV	GTF2IRD2B	246	Q6EKJ0
EATQMTYFNGSTNHG	SLC13A1	166	Q9BZW2
PATFSSMSHYGNQTL	FOXO3	456	O43524
HINTTHNSFGMQSYI	USH2A	4581	O75445
MASGQSQQSSHSADY	PRUNE2	501	Q8WUY3
QASHESIEDSMNSYG	RIMS4	61	Q9H426
ATNVMSTATGLHYSV	POU1F1	41	P28069
NTNNGSMVVHSSYDE	SEC24A	251	O95486
FGGSHMQQSSYNAFS	TBX15	496	Q96SF7
HYNTDGSMLFSASTD	SNRNP40	116	Q96DI7
TSVTSQISNGSHMSY	TAOK1	986	Q7L7X3
NHGYNVQDMTTTSIG	SI	111	P14410
MNGTSYYNSHSHSGE	SOX30	691	O94993
MEGDSYHNATTVNGT	CHRM5	1	P08912
MLHNSSGDFSQAHST	TRAF3IP2	61	O43734
HYTMTNGGSINSSTH	CLCN3	56	P51790
YNTPFQSMQSSGSAH	PLAG1	291	Q6DJT9
SVGSLGMSYSQEEAH	PLAG1	436	Q6DJT9
GMSYSQEEAHSSVSQ	PLAG1	441	Q6DJT9
NTHHVSLNMTGSGIY	VNN2	266	O95498
GTVSIFHMSDSYSET	PDCD11	1256	Q14690
DVSYMFGSSQSLLHS	TNS4	281	Q8IZW8
YMGQTSDHESQVTFT	TNR	101	Q92752
TASSNSAFSINVGHM	ZNF281	546	Q9Y2X9
AAAMASETSGHQGYQ	TCF20	66	Q9UGU0
SNGITMYGATQSQSD	ZDHHC14	341	Q8IZN3
SGMHSSSIVTAYENS	TRRAP	3006	Q9Y4A5
SHSQGYGYMHQTSVS	NEBL	931	O76041