Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionextracellular matrix structural constituent

COL4A2 TFPI2 LAMA3 LTBP1 SRPX MUC4 MUC6

5.42e-051881037GO:0005201
GeneOntologyMolecularFunctionopsonin binding

CFH C4A C4B

2.82e-04251033GO:0001846
GeneOntologyMolecularFunctionendopeptidase inhibitor activity

A2M TFPI2 LPA SERPINB2 C4A C4B

3.42e-041801036GO:0004866
GeneOntologyMolecularFunctionpeptidase regulator activity

A2M TFPI2 LPA SERPINB2 C4A C4B CTSS

3.74e-042571037GO:0061134
GeneOntologyMolecularFunctionpeptidase inhibitor activity

A2M TFPI2 LPA SERPINB2 C4A C4B

4.20e-041871036GO:0030414
GeneOntologyMolecularFunctioncomplement binding

CFH C4A C4B

5.93e-04321033GO:0001848
GeneOntologyMolecularFunctionendopeptidase regulator activity

A2M TFPI2 LPA SERPINB2 C4A C4B

6.14e-042011036GO:0061135
GeneOntologyBiologicalProcessregulation of body fluid levels

CFH PDGFRA KALRN TFPI2 GAS6 CEACAM1 TYRO3 LPA SERPINB2 UMOD WNK3

1.31e-0544210311GO:0050878
GeneOntologyBiologicalProcessglomerular filtration

GAS6 TBC1D8B JCHAIN UMOD

2.15e-05331034GO:0003094
GeneOntologyBiologicalProcesscell-cell adhesion

CFH SEMA4D TARM1 PDGFRA LAMA3 CEACAM1 HAVCR2 TYRO3 TMEM47 PTPRF CNTN5 UMOD CTNND2 NODAL MUC4 CNN3 CNTN1

2.30e-05107710317GO:0098609
GeneOntologyBiologicalProcessinnate immune response

A2M CFH TARM1 NLRX1 MUC19 SHMT2 TLR7 CREBBP CEACAM1 HAVCR2 TYRO3 TOMM70 JCHAIN UMOD C4A C4B CTSS

2.74e-05109210317GO:0045087
GeneOntologyBiologicalProcessrenal filtration

GAS6 TBC1D8B JCHAIN UMOD

3.05e-05361034GO:0097205
GeneOntologyBiologicalProcessblood coagulation

CFH PDGFRA TFPI2 GAS6 CEACAM1 TYRO3 LPA SERPINB2

4.85e-052601038GO:0007596
GeneOntologyBiologicalProcesscoagulation

CFH PDGFRA TFPI2 GAS6 CEACAM1 TYRO3 LPA SERPINB2

5.69e-052661038GO:0050817
GeneOntologyBiologicalProcesshemostasis

CFH PDGFRA TFPI2 GAS6 CEACAM1 TYRO3 LPA SERPINB2

6.00e-052681038GO:0007599
GeneOntologyBiologicalProcessactivation of immune response

A2M CFH NLRX1 TLR7 CREBBP CEACAM1 HAVCR2 TYRO3 TOMM70 C4A C4B CTSS

6.47e-0562310312GO:0002253
GeneOntologyBiologicalProcessregulation of immune response

A2M CFH TARM1 NLRX1 LAIR2 TLR7 CREBBP CEACAM1 HAVCR2 TYRO3 TOMM70 C4A C4B IGSF1 MUC4 CTSS

9.21e-05108510316GO:0050776
GeneOntologyBiologicalProcessapoptotic cell clearance

GAS6 TYRO3 C4A C4B

9.64e-05481034GO:0043277
GeneOntologyBiologicalProcessnegative regulation of response to biotic stimulus

A2M NLRX1 CEACAM1 HAVCR2 TYRO3 MUC4

1.11e-041511036GO:0002832
GeneOntologyBiologicalProcessnegative regulation of response to tumor cell

CEACAM1 HAVCR2 MUC4

1.51e-04211033GO:0002835
GeneOntologyBiologicalProcessnegative regulation of immune response to tumor cell

CEACAM1 HAVCR2 MUC4

1.51e-04211033GO:0002838
GeneOntologyBiologicalProcessparental behavior

KALRN NPAS3 ZFX

1.51e-04211033GO:0060746
GeneOntologyBiologicalProcessdefense response to symbiont

A2M CFH TARM1 NLRX1 MUC19 SHMT2 TLR7 CREBBP CEACAM1 HAVCR2 TYRO3 TOMM70 JCHAIN UMOD C4A C4B CTSS

2.04e-04128610317GO:0140546
GeneOntologyBiologicalProcessnegative regulation of response to external stimulus

A2M PDGFRA NLRX1 MUC19 CEACAM1 LRIG2 HAVCR2 TYRO3 LPA SERPINB2

2.32e-0450910310GO:0032102
GeneOntologyBiologicalProcessregulation of response to external stimulus

A2M CFH PDGFRA NLRX1 GAS6 MUC19 TLR7 CREBBP CEACAM1 LRIG2 HAVCR2 TYRO3 TOMM70 PTPRF LPA SERPINB2 CTSS

2.68e-04131610317GO:0032101
GeneOntologyBiologicalProcessnegative regulation of innate immune response

A2M NLRX1 CEACAM1 HAVCR2 TYRO3

2.69e-041141035GO:0045824
GeneOntologyBiologicalProcessregulation of innate immune response

A2M CFH NLRX1 TLR7 CREBBP CEACAM1 HAVCR2 TYRO3 TOMM70 CTSS

2.71e-0451910310GO:0045088
GeneOntologyBiologicalProcessregulation of response to biotic stimulus

A2M CFH NLRX1 TLR7 CREBBP CEACAM1 HAVCR2 TYRO3 TOMM70 MUC4 CTSS

3.68e-0464310311GO:0002831
GeneOntologyBiologicalProcessnegative regulation of blood coagulation

PDGFRA CEACAM1 LPA SERPINB2

3.95e-04691034GO:0030195
GeneOntologyBiologicalProcesscomplement activation

A2M CFH C4A C4B

4.18e-04701034GO:0006956
GeneOntologyBiologicalProcessnegative regulation of hemostasis

PDGFRA CEACAM1 LPA SERPINB2

4.18e-04701034GO:1900047
GeneOntologyBiologicalProcessnegative regulation of response to wounding

PDGFRA CEACAM1 LRIG2 LPA SERPINB2

4.26e-041261035GO:1903035
GeneOntologyBiologicalProcessnegative regulation of coagulation

PDGFRA CEACAM1 LPA SERPINB2

4.65e-04721034GO:0050819
GeneOntologyBiologicalProcessinterferon-beta production

NLRX1 TLR7 CREBBP TOMM70

4.90e-04731034GO:0032608
GeneOntologyBiologicalProcessregulation of interferon-beta production

NLRX1 TLR7 CREBBP TOMM70

4.90e-04731034GO:0032648
GeneOntologyBiologicalProcessdefense response to other organism

A2M CFH TARM1 NLRX1 MUC19 SHMT2 TLR7 CREBBP CEACAM1 HAVCR2 TYRO3 TOMM70 JCHAIN UMOD C4A C4B CTSS

5.78e-04140710317GO:0098542
GeneOntologyCellularComponentextracellular matrix

A2M COL4A2 FLG TFPI2 LAMA3 CELA2B EGFL6 LRIG2 PTPRZ1 P3H1 LPA LTBP1 SRPX MUC4 MUC6 CTSS

1.31e-0765610316GO:0031012
GeneOntologyCellularComponentexternal encapsulating structure

A2M COL4A2 FLG TFPI2 LAMA3 CELA2B EGFL6 LRIG2 PTPRZ1 P3H1 LPA LTBP1 SRPX MUC4 MUC6 CTSS

1.37e-0765810316GO:0030312
GeneOntologyCellularComponentcollagen-containing extracellular matrix

A2M COL4A2 FLG LAMA3 CELA2B EGFL6 PTPRZ1 P3H1 LPA LTBP1 SRPX MUC4 CTSS

2.06e-0653010313GO:0062023
GeneOntologyCellularComponentsymbiont cell surface

CFH C4A C4B

6.39e-0681033GO:0106139
GeneOntologyCellularComponentother organism part

CFH C4A C4B

9.55e-0691033GO:0044217
GeneOntologyCellularComponentactin-based cell projection

PDGFRA MYO1B CEACAM1 KPTN TBC1D10C TBC1D10A PTPRZ1 MUC4

7.06e-052781038GO:0098858
GeneOntologyCellularComponentGolgi lumen

GAS6 MUC19 UMOD MUC4 MUC6

2.05e-041091035GO:0005796
GeneOntologyCellularComponentkeratohyalin granule

FLG CELA2B

2.38e-0451032GO:0036457
GeneOntologyCellularComponentmicrovillus

PDGFRA MYO1B CEACAM1 TBC1D10A MUC4

3.59e-041231035GO:0005902
GeneOntologyCellularComponentendolysosome

TLR7 CLTC CTSS

4.28e-04301033GO:0036019
GeneOntologyCellularComponentadherens junction

LAMA3 CEACAM1 TMEM47 CTNND2 CNN3 WNK3

6.40e-042121036GO:0005912
GeneOntologyCellularComponentblood microparticle

A2M CFH JCHAIN C4A C4B

7.37e-041441035GO:0072562
GeneOntologyCellularComponentinner dynein arm

DNAH12 DNAH6

1.05e-03101032GO:0036156
MousePhenoabnormal lactation

KALRN PTPRF GUSB LPA JCHAIN

7.09e-0572845MP:0001882
MousePhenoabnormal response to infection

TFPI2 NLRX1 KDM6B CEACAM1 KPTN HAVCR2 TBC1D10C SP140L PTPRZ1 JCHAIN UMOD C4A C4B MUC4

8.25e-057148414MP:0005025
MousePhenoabnormal response to antigen

TFPI2 NLRX1 KDM6B CEACAM1 KPTN HAVCR2 TBC1D10C SP140L PTPRZ1 JCHAIN UMOD C4A C4B MUC4

9.86e-057268414MP:0020000
MousePhenorenal glomerular protein deposits

CFH TLR7 C4A C4B

1.14e-0442844MP:0020518
MousePhenoabnormal nest building behavior

KALRN NPAS3 CREBBP PTPRF

1.50e-0445844MP:0001447
MousePhenoabnormal exocrine gland physiology

KALRN TLR7 PTPRF GUSB LPA JCHAIN CTSS

1.74e-04196847MP:0013559
MousePhenoabnormal mammary gland physiology

KALRN PTPRF GUSB LPA JCHAIN

1.84e-0488845MP:0001881
MousePhenoabnormal apocrine gland physiology

KALRN PTPRF GUSB LPA JCHAIN

1.84e-0488845MP:0013555
MousePhenoabnormal social/conspecific interaction behavior

KALRN NPAS3 ETV5 CSMD3 CREBBP KPTN PTPRF GUSB SCN2A SUPT16H

2.08e-044218410MP:0002557
MousePhenoabnormal response to social novelty

CSMD3 KPTN SCN2A SUPT16H

2.09e-0449844MP:0020395
MousePhenoabnormal susceptibility to Coronaviridae infection

CEACAM1 C4A C4B MUC4

2.09e-0449844MP:0020948
MousePhenoincreased anti-single stranded DNA antibody level

TLR7 C4A C4B

2.22e-0420843MP:0004771
MousePhenoabnormal susceptibility to infection induced morbidity/mortality

TFPI2 CEACAM1 HAVCR2 SP140L JCHAIN C4A C4B MUC4

2.67e-04279848MP:0009785
MousePhenodecreased spleen germinal center size

SEMA4D C4A C4B

2.97e-0422843MP:0008484
DomainIG

SEMA4D TARM1 PDGFRA KALRN LAIR2 CEACAM1 LRIG2 HAVCR2 TYRO3 PTPRF CNTN5 IGSF1 CNTN1

6.15e-0742110413SM00409
DomainIg_sub

SEMA4D TARM1 PDGFRA KALRN LAIR2 CEACAM1 LRIG2 HAVCR2 TYRO3 PTPRF CNTN5 IGSF1 CNTN1

6.15e-0742110413IPR003599
DomainIGc2

SEMA4D PDGFRA KALRN CEACAM1 LRIG2 TYRO3 PTPRF CNTN5 IGSF1 CNTN1

7.62e-0723510410SM00408
DomainIg_sub2

SEMA4D PDGFRA KALRN CEACAM1 LRIG2 TYRO3 PTPRF CNTN5 IGSF1 CNTN1

7.62e-0723510410IPR003598
DomainIG_LIKE

SEMA4D TARM1 PDGFRA KALRN LAIR2 CEACAM1 LRIG2 HAVCR2 TYRO3 PTPRF CNTN5 IGSF1 CNTN1

3.38e-0649110413PS50835
DomainIg-like_dom

SEMA4D TARM1 PDGFRA KALRN LAIR2 CEACAM1 LRIG2 HAVCR2 TYRO3 PTPRF CNTN5 IGSF1 CNTN1

4.40e-0650310413IPR007110
DomainMacrogloblnA2_thiol-ester-bond

A2M C4A C4B

9.20e-0681043IPR019565
DomainThiol-ester_cl

A2M C4A C4B

9.20e-0681043PF10569
DomainMacrogloblnA2_CS

A2M C4A C4B

9.20e-0681043IPR019742
DomainIg_I-set

PDGFRA KALRN CEACAM1 LRIG2 TYRO3 PTPRF CNTN5 CNTN1

1.11e-051901048IPR013098
DomainI-set

PDGFRA KALRN CEACAM1 LRIG2 TYRO3 PTPRF CNTN5 CNTN1

1.11e-051901048PF07679
Domain-

SEMA4D TARM1 PDGFRA KALRN LAIR2 CEACAM1 LRIG2 HAVCR2 TYRO3 PTPRF PTPRZ1 CNTN5 IGSF1 CNTN1

1.83e-05663104142.60.40.10
DomainA2M

A2M C4A C4B

1.96e-05101043PF00207
DomainA2M_N_2

A2M C4A C4B

1.96e-05101043IPR011625
DomainA2M_comp

A2M C4A C4B

1.96e-05101043IPR011626
DomainA2M_recep

A2M C4A C4B

1.96e-05101043PF07677
DomainA2M_comp

A2M C4A C4B

1.96e-05101043PF07678
DomainA2M_N

A2M C4A C4B

1.96e-05101043PF01835
DomainA2M_N

A2M C4A C4B

1.96e-05101043IPR002890
DomainA-macroglobulin_rcpt-bd

A2M C4A C4B

1.96e-05101043IPR009048
DomainALPHA_2_MACROGLOBULIN

A2M C4A C4B

1.96e-05101043PS00477
DomainA2M_N_2

A2M C4A C4B

1.96e-05101043PF07703
DomainMacroglobln_a2

A2M C4A C4B

1.96e-05101043IPR001599
DomainIg-like_fold

SEMA4D TARM1 PDGFRA KALRN LAIR2 CEACAM1 LRIG2 HAVCR2 TYRO3 PTPRF PTPRZ1 CNTN5 IGSF1 CNTN1

3.65e-0570610414IPR013783
DomainIg_2

TARM1 LAIR2 CEACAM1 CNTN5 IGSF1

5.40e-05731045PF13895
DomainVWF_type-D

MUC19 MUC4 MUC6

8.91e-05161043IPR001846
DomainVWFD

MUC19 MUC4 MUC6

8.91e-05161043PS51233
DomainVWD

MUC19 MUC4 MUC6

8.91e-05161043SM00216
DomainVWD

MUC19 MUC4 MUC6

8.91e-05161043PF00094
Domainig

SEMA4D PDGFRA CEACAM1 LRIG2 TYRO3 CNTN5 IGSF1

9.34e-051901047PF00047
DomainImmunoglobulin

SEMA4D PDGFRA CEACAM1 LRIG2 TYRO3 CNTN5 IGSF1

9.34e-051901047IPR013151
DomainTerpenoid_cyclase/PrenylTrfase

A2M C4A C4B

1.29e-04181043IPR008930
DomainTBC

TBC1D2B TBC1D8B TBC1D10C TBC1D10A

1.59e-04491044SM00164
Domain-

TTC39C KDM6B ZC3H7A TOMM70 P3H1 CLTC EMC2

1.59e-0420710471.25.40.10
DomainRabGAP-TBC

TBC1D2B TBC1D8B TBC1D10C TBC1D10A

2.15e-04531044PF00566
DomainRab-GTPase-TBC_dom

TBC1D2B TBC1D8B TBC1D10C TBC1D10A

2.49e-04551044IPR000195
DomainTBC_RABGAP

TBC1D2B TBC1D8B TBC1D10C TBC1D10A

2.49e-04551044PS50086
Domainfn3

KALRN TYRO3 PTPRF PTPRZ1 CNTN5 CNTN1

2.92e-041621046PF00041
DomainAnaphylatoxin_comp_syst

C4A C4B

3.04e-0451042IPR018081
DomainAnaphylatoxn_comp_syst_dom

C4A C4B

3.04e-0451042IPR001840
DomainTPR-like_helical_dom

TTC39C KDM6B ZC3H7A TOMM70 P3H1 CLTC EMC2

3.27e-042331047IPR011990
DomainFN3

KALRN TYRO3 PTPRF PTPRZ1 CNTN5 CNTN1

5.92e-041851046SM00060
DomainANATO

C4A C4B

6.33e-0471042SM00104
DomainPept_M16_Zn_BS

UQCRC1 UQCRC2

6.33e-0471042IPR001431
DomainPept_M16_dom

UQCRC1 UQCRC2

6.33e-0471042IPR011237
DomainMetalloenz_LuxS/M16

UQCRC1 UQCRC2

6.33e-0471042IPR011249
DomainPeptidase_M16

UQCRC1 UQCRC2

6.33e-0471042PF00675
DomainANAPHYLATOXIN_2

C4A C4B

6.33e-0471042PS01178
DomainANAPHYLATOXIN_1

C4A C4B

6.33e-0471042PS01177
DomainPeptidase_M16_C

UQCRC1 UQCRC2

6.33e-0471042IPR007863
DomainANATO

C4A C4B

6.33e-0471042PF01821
DomainPeptidase_M16_C

UQCRC1 UQCRC2

6.33e-0471042PF05193
DomainPept_M16_N

UQCRC1 UQCRC2

6.33e-0471042IPR011765
Domain-

UQCRC1 UQCRC2

6.33e-04710423.30.830.10
DomainINSULINASE

UQCRC1 UQCRC2

6.33e-0471042PS00143
DomainAnaphylatoxin/fibulin

C4A C4B

6.33e-0471042IPR000020
DomainA2M_N_2

A2M C4A

8.41e-0481042SM01359
Domain-

A2M C4A

8.41e-04810422.60.40.690
DomainA2M_recep

A2M C4A

8.41e-0481042SM01361
DomainA2M

A2M C4A

8.41e-0481042SM01360
DomainFN3

KALRN TYRO3 PTPRF PTPRZ1 CNTN5 CNTN1

8.66e-041991046PS50853
DomainFN3_dom

KALRN TYRO3 PTPRF PTPRZ1 CNTN5 CNTN1

1.12e-032091046IPR003961
DomainEGF_CA

GAS6 EGFL6 UMOD LTBP1

1.36e-03861044PF07645
DomainGFP-like

EGFL6 UMOD

1.63e-03111042IPR023413
Domain-

EGFL6 UMOD

1.63e-031110422.40.155.10
DomainGrowth_fac_rcpt_

GAS6 LAMA3 EGFL6 UMOD LTBP1

1.80e-031561045IPR009030
DomainC8

MUC19 MUC6

1.95e-03121042PF08742
DomainTIL

MUC19 MUC6

1.95e-03121042PF01826
Domain-

A2M C4A

1.95e-031210421.50.10.20
DomainEGF

GAS6 LAMA3 EGFL6 UMOD LTBP1 MUC4

2.03e-032351046SM00181
DomainEGF_Ca-bd_CS

GAS6 EGFL6 UMOD LTBP1

2.11e-03971044IPR018097
DomainEGF_CA

GAS6 EGFL6 UMOD LTBP1

2.28e-03991044PS01187
DomainUnchr_dom_Cys-rich

MUC19 MUC6

2.30e-03131042IPR014853
DomainC8

MUC19 MUC6

2.30e-03131042SM00832
DomainTPR_REGION

TTC39C ZC3H7A TOMM70 P3H1 EMC2

2.30e-031651045PS50293
DomainTPR

TTC39C ZC3H7A TOMM70 P3H1 EMC2

2.30e-031651045PS50005
DomainASX_HYDROXYL

GAS6 EGFL6 UMOD LTBP1

2.36e-031001044PS00010
DomainDynein_heavy_chain_D4_dom

DNAH12 DNAH6

2.68e-03141042IPR024317
DomainDynein_heavy_dom-2

DNAH12 DNAH6

2.68e-03141042IPR013602
DomainDHC_N2

DNAH12 DNAH6

2.68e-03141042PF08393
DomainTIL_dom

MUC19 MUC6

2.68e-03141042IPR002919
DomainATPase_dyneun-rel_AAA

DNAH12 DNAH6

2.68e-03141042IPR011704
DomainAAA_8

DNAH12 DNAH6

2.68e-03141042PF12780
DomainAAA_5

DNAH12 DNAH6

2.68e-03141042PF07728
DomainEGF-like_dom

GAS6 LAMA3 EGFL6 UMOD LTBP1 MUC4

2.70e-032491046IPR000742
DomainEGF-type_Asp/Asn_hydroxyl_site

GAS6 EGFL6 UMOD LTBP1

2.92e-031061044IPR000152
DomainEGF_1

GAS6 LAMA3 EGFL6 UMOD LTBP1 MUC4

3.04e-032551046PS00022
DomainSushi

CFH CSMD3 SRPX

3.04e-03521043PF00084
DomainDHC_fam

DNAH12 DNAH6

3.08e-03151042IPR026983
DomainDynein_heavy

DNAH12 DNAH6

3.08e-03151042PF03028
DomainDynein_heavy_dom

DNAH12 DNAH6

3.08e-03151042IPR004273
DomainCCP

CFH CSMD3 SRPX

3.39e-03541043SM00032
DomainEGF-like_CS

GAS6 LAMA3 EGFL6 UMOD LTBP1 MUC4

3.41e-032611046IPR013032
DomainEGF_2

GAS6 LAMA3 EGFL6 UMOD LTBP1 MUC4

3.67e-032651046PS01186
DomainSUSHI

CFH CSMD3 SRPX

3.75e-03561043PS50923
DomainSushi_SCR_CCP_dom

CFH CSMD3 SRPX

3.95e-03571043IPR000436
DomainC345C

C4A C4B

3.95e-03171042SM00643
DomainEGF_CA

GAS6 EGFL6 UMOD LTBP1

4.82e-031221044SM00179
DomainNTR

C4A C4B

4.94e-03191042PF01759
DomainNetrin_module_non-TIMP

C4A C4B

4.94e-03191042IPR018933
Pubmed

In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine.

A2M CFH COL4A2 GAS6 LAMA3 VTA1 CEACAM1 TBC1D10A GUSB JCHAIN CLTC UMOD C4A C4B MUC4 CRISPLD1 CNTN1

1.94e-0810701041723533145
Pubmed

Expression of the immunoglobulin superfamily cell adhesion molecules in the developing spinal cord and dorsal root ganglion.

KALRN CEACAM1 LRIG2 TYRO3 PTPRF CNTN5 IGSF1 CNTN1

3.28e-08162104825826454
Pubmed

Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry.

A2M CFH CEACAM1 PTPRF PTPRZ1 GUSB JCHAIN C4A CNTN1

8.52e-08257104916335952
Pubmed

Complement activation via alternative pathway is critical in the development of laser-induced choroidal neovascularization: role of factor B and factor H.

CFH C4A C4B

5.16e-076104316849499
Pubmed

Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.

SHMT2 MYO1B NOL10 PCF11 TOMM70 PTPRF PTPRZ1 P3H1 CLTC SUPT16H LTBP1 PRPF38A MARVELD2 UQCRC2

3.02e-0610491041427880917
Pubmed

Combination of factor H mutation and properdin deficiency causes severe C3 glomerulonephritis.

CFH C4A C4B

4.21e-0611104323204401
Pubmed

MECP2 directly interacts with RNA polymerase II to modulate transcription in human neurons.

FLG KALRN ZMYM2 SHMT2 MYO1B THOC5 PCF11 NWD2 CLTC SUPT16H SF3A3 SRPX PRPF38A UQCRC2

4.31e-0610821041438697112
Pubmed

Copy number analysis of complement C4A, C4B and C4A silencing mutation by real-time quantitative polymerase chain reaction.

C4A C4B

8.86e-062104222737222
Pubmed

Deficiency of C4 from donor or recipient mouse fails to prevent renal allograft rejection.

C4A C4B

8.86e-062104216565498
Pubmed

Complete deficiencies of complement C4A and C4B including 2-bp insertion in codon 1213 are genetic risk factors of systemic lupus erythematosus in Thai populations.

C4A C4B

8.86e-062104215998580
Pubmed

High-throughput analysis of the C4 polymorphism by a combination of MLPA and isotype-specific ELISA's.

C4A C4B

8.86e-062104219062096
Pubmed

Activation of innate and humoral immunity in the peripheral nervous system of ALS transgenic mice.

C4A C4B

8.86e-062104219933335
Pubmed

Structural basis for the C4d.1/C4d.2 serologic allotypes of murine complement component C4.

C4A C4B

8.86e-06210422459207
Pubmed

Antigen-induced B cell apoptosis is independent of complement C4.

C4A C4B

8.86e-062104217645767
Pubmed

Anti-DNA autoreactivity in C4-deficient mice.

C4A C4B

8.86e-062104212207352
Pubmed

Complement C4A and C4B Gene Copy Number Study in Alzheimer's Disease Patients.

C4A C4B

8.86e-062104227758680
Pubmed

Genetically determined partial complement C4 deficiency states are not independent risk factors for SLE in UK and Spanish populations.

C4A C4B

8.86e-062104222387014
Pubmed

Complement C4 maintains peripheral B-cell tolerance in a myeloid cell dependent manner.

C4A C4B

8.86e-062104223749435
Pubmed

Copy number variations of complement component C4 are associated with Behçet's disease but not with ankylosing spondylitis associated with acute anterior uveitis.

C4A C4B

8.86e-062104223918728
Pubmed

Molecular genetics of androgen-dependent and -independent expression of mouse sex-limited protein.

C4A C4B

8.86e-06210423037333
Pubmed

Evaluation of Tyro3 expression, Gas6-mediated Akt phosphorylation, and the impact of anti-Tyro3 antibodies in melanoma cell lines.

GAS6 TYRO3

8.86e-062104223570341
Pubmed

Evidence of a role for C4 in modulating interstitial inflammation in experimental glomerulonephritis.

C4A C4B

8.86e-062104211726230
Pubmed

Quantitative variations in the expression of the mouse serum antigen Ss and its sex-limited allotype Slp.

C4A C4B

8.86e-06210424216347
Pubmed

Sequence determination of the thiolester site of the fourth component of human complement.

C4A C4B

8.86e-06210426950384
Pubmed

Visual demonstration of the organization of the human complement C4 and 21-hydroxylase genes by high-resolution fluorescence in situ hybridization.

C4A C4B

8.86e-06210428660986
Pubmed

Tissue-specific RNA processing for the complement C4 gene transcript in the H-2k mouse strain.

C4A C4B

8.86e-06210428428773
Pubmed

Reevaluation of the roles of protein S and Gas6 as ligands for the receptor tyrosine kinase Rse/Tyro 3.

GAS6 TYRO3

8.86e-06210427634325
Pubmed

Complement C4 deficiency--a plausible risk factor for non-tuberculous mycobacteria (NTM) infection in apparently immunocompetent patients.

C4A C4B

8.86e-062104224638111
Pubmed

Transcriptional repression of C4 complement by hepatitis C virus proteins.

C4A C4B

8.86e-062104221345967
Pubmed

Elevated Plasma Growth Arrest-Specific 6 Protein Levels Are Associated with the Severity of Disease During Hantaan Virus Infection in Humans.

GAS6 TYRO3

8.86e-062104228537534
Pubmed

Restriction fragment analysis of H-2 recombinant mouse strains with crossovers between E alpha and C4 genes.

C4A C4B

8.86e-06210422572548
Pubmed

The complement component C4 of mammals.

C4A C4B

8.86e-06210422302180
Pubmed

Gene CNVs and protein levels of complement C4A and C4B as novel biomarkers for partial disease remissions in new-onset type 1 diabetes patients.

C4A C4B

8.86e-062104222151770
Pubmed

C4d-positive chronic rejection: a frequent entity with a poor outcome.

C4A C4B

8.86e-062104218091514
Pubmed

Comprehensive approach to study complement C4 in systemic lupus erythematosus: Gene polymorphisms, protein levels and functional activity.

C4A C4B

8.86e-062104229080553
Pubmed

Genes for murine fourth complement component (C4) and sex-limited protein (Slp) identified by hybridization to C4- and Slp-specific cDNA.

C4A C4B

8.86e-06210426589636
Pubmed

C4 Deficiency is a predisposing factor for Streptococcus pneumoniae-induced autoantibody production.

C4A C4B

8.86e-062104225339671
Pubmed

The anticoagulation factor protein S and its relative, Gas6, are ligands for the Tyro 3/Axl family of receptor tyrosine kinases.

GAS6 TYRO3

8.86e-06210427867073
Pubmed

A study of association of the complement C4 mutations with systemic lupus erythematosus in the Malaysian population.

C4A C4B

8.86e-062104217728371
Pubmed

Structure and organization of the C4 genes.

C4A C4B

8.86e-06210426149580
Pubmed

Sequence heterogeneity of murine complementary DNA clones related to the C4 and C4-Slp isoforms of the fourth complement component.

C4A C4B

8.86e-06210426149581
Pubmed

The follicular dendritic cell restricted epitope, FDC-M2, is complement C4; localization of immune complexes in mouse tissues.

C4A C4B

8.86e-062104212115608
Pubmed

Biochemistry and biology of anaphylatoxins.

C4A C4B

8.86e-06210423542363
Pubmed

C4 from C4-high and C4-low mouse strains have identical sequences in the region corresponding to the isotype-specific segment of human C4.

C4A C4B

8.86e-06210422387317
Pubmed

Identification of the size and antigenic determinants of the human C4 gene by a polymerase chain-reaction-based amplification method.

C4A C4B

8.86e-062104216908004
Pubmed

Structural studies on the murine fourth component of complement (C4). IV. Demonstration that C4 and Slp are encoded by separate loci.

C4A C4B

8.86e-06210427365238
Pubmed

Interaction between the labile binding sites of the fourth (C4) and fifth (C5) human complement proteins and erythrocyte cell membranes.

C4A C4B

8.86e-06210427391573
Pubmed

Peritubular capillary C4d deposition in lupus nephritis different from antibody-mediated renal rejection.

C4A C4B

8.86e-062104217971360
Pubmed

Clinical features of patients with homozygous complement C4A or C4B deficiency.

C4A C4B

8.86e-062104229928053
Pubmed

Analysis of C4 and the C4 binding protein in the MRL/lpr mouse.

C4A C4B

8.86e-062104217971229
Pubmed

Genetic deficiency of C4 presenting with recurrent infections and a SLE-like disease. Genetic and immunologic studies.

C4A C4B

8.86e-06210426881182
Pubmed

Cathepsin S inhibitor prevents autoantigen presentation and autoimmunity.

MUC19 CTSS

8.86e-062104212163455
Pubmed

Partial C4 deficiency in juvenile idiopathic arthritis patients.

C4A C4B

8.86e-062104217921792
Pubmed

Complement activation and complement receptors on follicular dendritic cells are critical for the function of a targeted adjuvant.

C4A C4B

8.86e-062104221880985
Pubmed

Amino acid sequence around the thiol and reactive acyl groups of human complement component C4.

C4A C4B

8.86e-06210426978711
Pubmed

Plasma Complement 3 and Complement 4 Are Promising Biomarkers for Distinguishing NMOSD From MOGAD and Are Associated With the Blood-Brain-Barrier Disruption in NMOSD.

C4A C4B

8.86e-062104235898513
Pubmed

Borrelia burgdorferi outer surface protein C (OspC) binds complement component C4b and confers bloodstream survival.

C4A C4B

8.86e-062104228873507
Pubmed

Studies on the murine Ss protein: demonstration that the Ss protein is functionally the fourth component of complement.

C4A C4B

8.86e-0621042276882
Pubmed

Amino acid sequence of a polymorphic segment from fragment C4d of human complement component C4.

C4A C4B

8.86e-06210426832377
Pubmed

Recombination of two homologous MHC class III genes of the mouse (C4 and Slp) that accounts for the loss of testosterone dependence of sex-limited protein expression.

C4A C4B

8.86e-06210423794341
Pubmed

Fine-tuned characterization of RCCX copy number variants and their relationship with extended MHC haplotypes.

C4A C4B

8.86e-062104222785613
Pubmed

Association between complement 4 copy number variation and systemic lupus erythematosus: a meta-analysis.

C4A C4B

8.86e-062104232691186
Pubmed

The androgen-dependent C4-Slp gene is driven by a constitutively competent promoter.

C4A C4B

8.86e-06210428390682
Pubmed

Structure and expression of murine fourth complement component (C4) and sex-limited protein (Slp).

C4A C4B

8.86e-06210423902619
Pubmed

Structural polymorphism of murine C4 and its linkage to H-2.

C4A C4B

8.86e-06210427373044
Pubmed

The chemical structure of the C4d fragment of the human complement component C4.

C4A C4B

8.86e-06210423696167
Pubmed

The TAM receptor Tyro3 regulates myelination in the central nervous system.

GAS6 TYRO3

8.86e-062104228145605
Pubmed

Restriction fragment length polymorphism of the murine C4 and Slp genes: two C4 groups.

C4A C4B

8.86e-06210421357031
Pubmed

Structural comparison of human C4A3 and C4B1 after proteolytic activation by C1s.

C4A C4B

8.86e-062104216098595
Pubmed

Increased frequency of C4B*Q0 alleles in patients with Henoch-Schönlein purpura.

C4A C4B

8.86e-062104215787745
Pubmed

Neuropil contraction in relation to Complement C4 gene copy numbers in independent cohorts of adolescent-onset and young adult-onset schizophrenia patients-a pilot study.

C4A C4B

8.86e-062104230026462
Pubmed

A molecular map of the human major histocompatibility complex class III region linking complement genes C4, C2 and factor B.

C4A C4B

8.86e-06210426559257
Pubmed

Complement C4 Is Reduced in iPSC-Derived Astrocytes of Autism Spectrum Disorder Subjects.

C4A C4B

8.86e-062104234299197
Pubmed

Assessment of complement C4 gene copy number using the paralog ratio test.

C4A C4B

8.86e-062104220506482
Pubmed

Polymerase chain reaction based C4AQ0 and C4BQ0 genotyping: association with systemic lupus erythematosus in southwest Han Chinese.

C4A C4B

8.86e-062104212480675
Pubmed

Low C4, C4A and C4B gene copy numbers are stronger risk factors for juvenile-onset than for adult-onset systemic lupus erythematosus.

C4A C4B

8.86e-062104226800705
Pubmed

Murine complement C4 is not required for experimental autoimmune encephalomyelitis.

C4A C4B

8.86e-062104215390104
Pubmed

Importance of the alpha 3-fragment of complement C4 for the binding with C4b-binding protein.

C4A C4B

8.86e-06210421699796
Pubmed

Molecular cloning and characterization of complementary and genomic DNA clones for mouse C4 and Slp.

C4A C4B

8.86e-06210422997024
Pubmed

CREB-binding protein regulates apoptosis and growth of HMECs grown in reconstituted ECM via laminin-5.

LAMA3 CREBBP

8.86e-062104216219677
Pubmed

Constitutive expression of Slp genes in mouse strain B10.WR directed by C4 regulatory sequences.

C4A C4B

8.86e-06210423624865
Pubmed

Determination of the loss of function complement C4 exon 29 CT insertion using a novel paralog-specific assay in healthy UK and Spanish populations.

C4A C4B

8.86e-062104221857912
Pubmed

Isolation of cDNA clones specifying the fourth component of mouse complement and its isotype, sex-limited protein.

C4A C4B

8.86e-06210426208559
Pubmed

The role of the histocompatibility-2-linked Ss-Slp region in the control of mouse complement.

C4A C4B

8.86e-06210424514997
Pubmed

The inheritance of susceptibility to the Gross leukemia virus in mice.

C4A C4B

8.86e-06210425919331
Pubmed

An ancient provirus has imposed androgen regulation on the adjacent mouse sex-limited protein gene.

C4A C4B

8.86e-06210423167981
Pubmed

The dichotomous size variation of human complement C4 genes is mediated by a novel family of endogenous retroviruses, which also establishes species-specific genomic patterns among Old World primates.

C4A C4B

8.86e-06210427545960
Pubmed

Insights on the relationship between complement component C4 serum concentrations and C4 gene copy numbers in a Western Australian systemic lupus erythematosus cohort.

C4A C4B

8.86e-062104230041577
Pubmed

Complete cDNA sequence of the fourth component of murine complement.

C4A C4B

8.86e-06210423862104
Pubmed

The BS variant of C4 protects against age-related loss of white matter microstructural integrity.

C4A C4B

8.86e-062104234358307
Pubmed

Reconstitution of mitochondrial processing peptidase from the core proteins (subunits I and II) of bovine heart mitochondrial cytochrome bc(1) complex.

UQCRC1 UQCRC2

8.86e-062104211073949
Pubmed

Acute renal allograft rejection: diagnostic significance of focal peritubular capillary C4d.

C4A C4B

8.86e-062104218360261
Pubmed

Co-expression of TIM-3 and CEACAM1 promotes T cell exhaustion in colorectal cancer patients.

CEACAM1 HAVCR2

8.86e-062104228038383
Pubmed

A receptor tyrosine kinase, Sky, and its ligand Gas 6 are expressed in gonads and support primordial germ cell growth or survival in culture.

GAS6 TYRO3

8.86e-06210428954722
Pubmed

Schizophrenia risk from complex variation of complement component 4.

C4A C4B

8.86e-062104226814963
Pubmed

Promoter elements of the mouse complement C4 gene critical for transcription activation and start site location.

C4A C4B

8.86e-06210428132550
Pubmed

Substitution of a single amino acid (aspartic acid for histidine) converts the functional activity of human complement C4B to C4A.

C4A C4B

8.86e-06210422395880
Pubmed

Immune evasion by acquisition of complement inhibitors: the mould Aspergillus binds both factor H and C4b binding protein.

CFH C4B

8.86e-062104217915330
Pubmed

Effects of Complement C4 Gene Copy Number Variations, Size Dichotomy, and C4A Deficiency on Genetic Risk and Clinical Presentation of Systemic Lupus Erythematosus in East Asian Populations.

C4A C4B

8.86e-062104226814708
Pubmed

cDNA clone spanning the alpha-gamma subunit junction in the precursor of the murine fourth complement component (C4).

C4A C4B

8.86e-06210426192448
CytobandEnsembl 112 genes in cytogenetic band chr8q23

TRHR CSMD3 EMC2

2.17e-04511043chr8q23
GeneFamilyImmunoglobulin like domain containing

SEMA4D TARM1 LAIR2 CEACAM1 TYRO3 CNTN5 IGSF1 CNTN1

8.73e-07193718594
GeneFamilyBlood group antigens|CD molecules|I-set domain containing|Immunoglobulin like domain containing

PDGFRA KALRN LRIG2 TYRO3 PTPRF CNTN5 CNTN1

3.21e-06161717593
GeneFamilyC3 and PZP like, alpha-2-macroglobulin domain containing

A2M C4A C4B

4.79e-0697131234
GeneFamilyFibronectin type III domain containing

KALRN TYRO3 PTPRF PTPRZ1 CNTN5 CNTN1

3.90e-05160716555
GeneFamilyCD molecules|Mucins

MUC19 MUC4 MUC6

7.34e-0521713648
GeneFamilyComplement system|Sushi domain containing

CFH C4A C4B

3.78e-0436713492
GeneFamilyMitochondrial complex III: ubiquinol-cytochrome c reductase complex subunits|Apoptosome

UQCRC1 UQCRC2

6.70e-0410712642
GeneFamilyTetratricopeptide repeat domain containing|Bardet-Biedl syndrome associated|BBSome

TTC39C ZC3H7A TOMM70 EMC2

1.09e-03115714769
GeneFamilyHyalectan proteoglycans|V-set domain containing|Sushi domain containing|C-type lectin domain containing

CFH CSMD3 SRPX

1.46e-03577131179
GeneFamilyDyneins, axonemal

DNAH12 DNAH6

1.99e-0317712536
GeneFamilyProtein tyrosine phosphatases, receptor type

PTPRF PTPRZ1

3.04e-0321712813
GeneFamilyGlycosyltransferase family 6|Blood group antigens

C4A C4B

9.27e-0337712454
CoexpressionNABA_MATRISOME

A2M COL4A2 FLG SEMA4D ADAM7 GAS6 MUC19 LAMA3 CELA2B EGFL6 P3H1 LPA SERPINB2 LTBP1 SRPX NODAL MUC4 CRISPLD1 MUC6 CTSS

3.35e-09102610420M5889
CoexpressionNABA_MATRISOME

A2M COL4A2 SEMA4D ADAM7 GAS6 MUC19 LAMA3 CELA2B EGFL6 P3H1 LPA SERPINB2 LTBP1 SRPX NODAL MUC4 CRISPLD1 MUC6 CTSS

1.50e-08100810419MM17056
CoexpressionGSE37605_FOXP3_FUSION_GFP_VS_IRES_GFP_TREG_C57BL6_DN

FMO2 KALRN NBEAL1 GAS6 MYO1B CSMD3 SERPINB2 SRPX

5.24e-071761048M8790
CoexpressionNABA_MATRISOME_ASSOCIATED

A2M FLG SEMA4D ADAM7 MUC19 CELA2B EGFL6 P3H1 LPA SERPINB2 NODAL MUC4 MUC6 CTSS

1.64e-0675110414M5885
CoexpressionNABA_MATRISOME_ASSOCIATED

A2M SEMA4D ADAM7 MUC19 CELA2B EGFL6 P3H1 LPA SERPINB2 NODAL MUC4 MUC6 CTSS

7.30e-0673810413MM17058
CoexpressionNABA_ECM_REGULATORS

A2M ADAM7 CELA2B P3H1 LPA SERPINB2 CTSS

4.69e-052381047M3468
CoexpressionNABA_ECM_REGULATORS

A2M ADAM7 CELA2B P3H1 LPA SERPINB2 CTSS

5.21e-052421047MM17062
CoexpressionAtlasMyeloid Cells, MF.II-480hi.PC, F4/80hi CD115hi CD11b+ MHC II- CD11c-, Peritoneal Cavity, avg-3

CFH LAMA3 TLR7 CEACAM1 DNAH12 GUSB SERPINB2 C4A C4B LTBP1 CTSS

1.01e-0543810411GSM605850_500
CoexpressionAtlasMyeloid Cells, MF.Thio5.II-480hi.PC, CD115+ MHC II- F480hi Siglec F-, Peritoneal Cavity, avg-3

CFH GAS6 TLR7 CEACAM1 DNAH12 GUSB SERPINB2 C4B LTBP1 CTSS

6.18e-0544110410GSM605862_500
CoexpressionAtlaskidney_adult_JuxtaGlom_Ren1_Captopr_k-means-cluster#2_top-relative-expression-ranked_100

CFH FMO2

7.10e-0531042gudmap_kidney_adult_JuxtaGlom_Ren1_Captopr_k2_100
CoexpressionAtlasStromal Cells, St.31-38-44-.SLN, CD45- gp38- CD31- CD44-, Lymph Node, avg-2

CFH COL4A2 FMO2 PDGFRA GAS6 MYO1B TMEM47 C4B SRPX CNN3

7.72e-0545310410GSM777067_500
CoexpressionAtlaskidney_adult_RenalCapsule_k-means-cluster#2_top-relative-expression-ranked_1000

CFH FMO2 PDGFRA GAS6 PTPRZ1 SCN2A C4B SRPX CTSS

8.43e-053691049gudmap_kidney_adult_RenalCapsule_k2_1000
CoexpressionAtlasStromal Cells, FRC.MLN, gp38+ CD31- CD140a+, Lymph Node, avg-5

CFH COL4A2 FMO2 PDGFRA GAS6 PTPRF C4A C4B LTBP1 SRPX

9.75e-0546610410GSM777050_500
ToppCelltumor_Lung-Fibroblasts|tumor_Lung / Location, Cell class and cell subclass

A2M CFH FMO2 PDGFRA GAS6 EGFL6 LTBP1 SRPX CNN3

1.08e-092001049073a68b5ce232203ffee86342cba2a00d907e119
ToppCell356C-Fibroblasts-Fibroblast-C_(Myofibroblast)-|356C / Donor, Lineage, Cell class and subclass (all cells)

A2M CFH COL4A2 FMO2 PDGFRA TMEM47 LTBP1 SRPX

9.14e-091771048cdfd2f0ee2f692271b1525e414b0f645cdadb1f6
ToppCell356C-Fibroblasts-Fibroblast-C_(Myofibroblast)|356C / Donor, Lineage, Cell class and subclass (all cells)

A2M CFH COL4A2 FMO2 PDGFRA TMEM47 LTBP1 SRPX

9.14e-091771048db222faaecbe5600da39277243c4e7e764eb63c9
ToppCell21-Trachea-Mesenchymal-Airway_Smooth_Muscle|Trachea / Age, Tissue, Lineage and Cell class

A2M COL4A2 PDGFRA ETV5 PLPPR4 SRPX HHIPL1 IGSF1

1.24e-08184104886a96cd88e50eacad1f0badfbbf6dc626f41725e
ToppCell5'-GW_trimst-2-LargeIntestine-Mesenchymal-Pericytes-angiogenic_pericyte|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

A2M COL4A2 FMO2 GAS6 LAMA3 MYO1B EGFL6 PLPPR4

1.29e-08185104835d39a1d04c871edcfb749653538dc5fd0054281
ToppCell356C-Epithelial_cells-Epithelial-I_(AT1)|356C / Donor, Lineage, Cell class and subclass (all cells)

COL4A2 FMO2 GAS6 LAMA3 MYO1B PTPRF LIPH CTNND2

1.95e-08195104807a3ef6b0f1201fe2bcb9ea426b8f7a69beb4904
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

A2M CFH COL4A2 FMO2 PDGFRA KALRN LTBP1 CNTN1

1.95e-081951048cad6563cc51d212554152c727fc2c249c6a07e4d
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

A2M CFH COL4A2 FMO2 PDGFRA KALRN LTBP1 CNTN1

1.95e-081951048783bfa8110161cbd6def50ce849cae676c39c458
ToppCell356C-Epithelial_cells-Epithelial-I_(AT1)-|356C / Donor, Lineage, Cell class and subclass (all cells)

COL4A2 FMO2 GAS6 LAMA3 MYO1B PTPRF LIPH CTNND2

1.95e-081951048b65511770ed67f7447847e2187555b362988af45
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

A2M CFH COL4A2 FMO2 PDGFRA KALRN LTBP1 CNTN1

2.11e-08197104809946ee8dfb15a2a32da06e5b331f3277ee934f4
ToppCellmedial-2-mesenchymal|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

A2M CFH COL4A2 FMO2 PDGFRA GAS6 MYO1B EGFL6

2.37e-082001048a9d8aa5bcf383d98a9e2eaf4b1f8466982d6b088
ToppCell15-Airway|15 / Age, Tissue, Lineage and Cell class

A2M CFH EGFL6 P3H1 LTBP1 SRPX CRISPLD1 CNN3

2.37e-082001048ba4b8d5becf81351901c2ecac74ffa28e29586f3
ToppCellmedial-mesenchymal|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

A2M CFH COL4A2 FMO2 PDGFRA GAS6 MYO1B EGFL6

2.37e-0820010484f19e1e40966e27779bf77e8c170ed3ecc24353e
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Lamp5-Lamp5_Ntn1_Npy2r|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

NPAS3 TBC1D8B PTPRZ1 CNTN5 LTBP1 ASIC4 CRISPLD1

5.88e-0814810475e738522d4ad35e08bc4ff8c41b7bea38ec6ef95
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Lamp5-Lamp5_Ntn1_Npy2r|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

NPAS3 TBC1D8B PTPRZ1 CNTN5 LTBP1 ASIC4 CRISPLD1

7.06e-0815210478ff5a178a8f3550d89a003c0858820aab3773386
ToppCelltumor_Lung-Fibroblasts-Undetermined|tumor_Lung / Location, Cell class and cell subclass

A2M CFH FMO2 PDGFRA GAS6 LTBP1 SRPX

2.32e-07181104753bcab4d6df4a3255d81877ba22fb95d4492ce9f
ToppCell5'-Adult-LymphNode-Mesenchymal-fibroblastic-Transitional_Stromal_3_(C3+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

COL4A2 FMO2 PDGFRA TFPI2 KDM6B SERPINB2 SRPX

2.32e-071811047ab66a89f316b935d9ba1277426d976b1e9e39757
ToppCell5'-GW_trimst-2-LymphNode-Mesenchymal-Pericytes-angiogenic_pericyte|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

A2M COL4A2 GAS6 LAMA3 MYO1B EGFL6 PLPPR4

2.89e-071871047b8f88599e22b9b345c7ec3bbecd87a8b2a033f9f
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_1|Adult / Lineage, Cell type, age group and donor

COL4A2 FMO2 GAS6 LAMA3 MYO1B PTPRF CTNND2

2.89e-07187104777f78aec946bc6bd85c29aee9ca978ce49f853a3
ToppCellIPF-Stromal-SMC|World / Disease state, Lineage and Cell class

COL4A2 KALRN EGFL6 TMEM47 C4B LTBP1 CNN3

3.00e-071881047b66264e8f8d536ed2beec31e6746c687718f239b
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_1-D231|Adult / Lineage, Cell type, age group and donor

COL4A2 FMO2 GAS6 LAMA3 MYO1B PTPRF CTNND2

3.11e-0718910475a04cb25f8f0447b2cecdb6c3695029281aca26d
ToppCellwk_20-22-Mesenchymal-Myofibro_&_SMC-Myofibro_2|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

COL4A2 PDGFRA ETV5 PLPPR4 LTBP1 IGSF1 CNN3

3.58e-0719310472f203f6f0c2135acb046c9351a633c3b5b254a46
ToppCell(5)_Fibroblast-C_(Myofibroblast)|World / Lung cell shreds - cell class (v4) and cell subclass (v4)

A2M CFH FMO2 EGFL6 TMEM47 PLPPR4 LTBP1

3.71e-07194104729a72e565c19407bbd198cfbc2a78106fe830d05
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

A2M COL4A2 KALRN MYO1B LTBP1 HHIPL1 CNTN1

3.84e-071951047803f714d91f2d97ecbee8c15a5139fd9310f66c7
ToppCellBronchial-NucSeq-Epithelial-Epi_alveolar-AT1|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

COL4A2 FMO2 GAS6 LAMA3 MYO1B PTPRF CTNND2

3.84e-071951047a71ba5e4043e2d35a45a2c60a96b087e31832345
ToppCelltumor_Lung-Fibroblasts-Smooth_muscle_cells|tumor_Lung / Location, Cell class and cell subclass

A2M COL4A2 FMO2 GAS6 EGFL6 LTBP1 CNN3

3.84e-071951047ea9ff25020c2fcd1bab80e1829af0f4e4777de8b
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

A2M COL4A2 KALRN MYO1B LTBP1 HHIPL1 CNTN1

3.84e-0719510474f70157d42a16ff0259bc24a62803c4df4285c44
ToppCellfacs-Trachea-3m-Mesenchymal-fibroblast-fibroblast_of_trachea-tracheal_fibroblast_l1|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CFH FMO2 PDGFRA GAS6 C4B LTBP1 SRPX

3.98e-071961047d4676a6b0d9e417795fc9a6bcb1762d3dd656ca9
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

A2M CFH COL4A2 FMO2 PDGFRA KALRN LTBP1

3.98e-0719610473a6c942e2907aa07b5e12dbf9019d18f7bfca507
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

A2M CFH COL4A2 FMO2 PDGFRA KALRN LTBP1

3.98e-071961047bba88e91cd3e3a6f5a9b443e3a4da33c5b455e70
ToppCellASK428-Epithelial-Type_1|ASK428 / Donor, Lineage and Cell class of Lung cells from Dropseq

COL4A2 FMO2 GAS6 LAMA3 MYO1B PTPRF LIPH

4.11e-0719710479ae6661c307791c3f0ecd3d378e3d917565e5498
ToppCellLPS_anti-TNF-Epithelial_alveolar-AT_1-AT1|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

FMO2 LAMA3 MYO1B PTPRF LIPH SCN2A CNN3

4.26e-0719810471282db321e27499d310339d6383974614e295a20
ToppCellAT1-AT2_cells|World / lung cells shred on cell class, cell subclass, sample id

COL4A2 FMO2 GAS6 LAMA3 MYO1B PTPRF CNN3

4.26e-071981047a5b3617ea2ed4bffba59edcf6284799c2b3bbb29
ToppCelltumor_Lung-Fibroblasts-COL13A1+_matrix_FBs|tumor_Lung / Location, Cell class and cell subclass

A2M CFH FMO2 PDGFRA TMEM47 LTBP1 CNN3

4.26e-0719810472d7842f352273b6b823c86eb548b9f4a4cddf0ae
ToppCell10x3'2.3-week_14-16-Mesenchymal_osteo-stroma-osteoblast_precursor|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

A2M CFH PDGFRA TMEM47 SRPX CRISPLD1 CNN3

4.26e-0719810479d61483b0decac2fe90045b3474843360b2c49b3
ToppCell10x_3'_v2v3-Neoplastic-Differentiated-like-AC-like-AC-like-G|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

PDGFRA PTPRZ1 ASIC4 CTNND2 CRISPLD1 CNN3 CNTN1

4.26e-07198104701d563ccdc0da02dac04169e713844fecb4233a1
ToppCell390C-Fibroblasts-Fibroblast-K_(Pericytes)|390C / Donor, Lineage, Cell class and subclass (all cells)

A2M COL4A2 GAS6 EGFL6 TMEM47 LTBP1 CNN3

4.26e-071981047c82a151f9f1477d4a401457173b8d72af776c137
ToppCellTracheal-10x5prime-Stromal-Peri/Epineurial_-NAF_endoneurial|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

A2M C4A C4B LTBP1 SRPX CRISPLD1 CNTN1

4.26e-0719810477a0c4dbc8c99968d42af00a718f4fedc544599ec
ToppCell390C-Fibroblasts-Fibroblast-K_(Pericytes)-|390C / Donor, Lineage, Cell class and subclass (all cells)

A2M COL4A2 GAS6 EGFL6 TMEM47 LTBP1 CNN3

4.26e-071981047dc63b56bb6291e527b172d603569376286262845
ToppCell(5)_Fibroblast-A_(Fibroblast_progenitors)|World / Lung cell shreds - cell class (v4) and cell subclass (v4)

A2M CFH FMO2 PDGFRA LTBP1 SRPX CNN3

4.40e-071991047b783917fe0a9725a680aa430a42f02ce294900ef
ToppCellTracheal-10x3prime_v2-Stromal-Fibroblastic-Fibro_peribronchial|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

A2M CFH FMO2 PDGFRA PLPPR4 LTBP1 SRPX

4.40e-071991047e9009eee7f77b9c9917f8e0e723001d9e76eb553
ToppCell10x_3'_v2v3-Neoplastic-Differentiated-like-AC-like-AC-like|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

PDGFRA NPAS3 PTPRZ1 SRPX CTNND2 CRISPLD1 CNN3

4.40e-07199104704e5cfb85c681fd3f4c1151062e4a0f460b55d5f
ToppCell5'-GW_trimst-2-SmallIntestine-Mesenchymal-Pericytes-angiogenic_pericyte|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

A2M COL4A2 GAS6 MYO1B EGFL6 PLPPR4 CNN3

4.40e-0719910479e32644b93fb1c4946dbe388fd5c357304d14e36
ToppCell368C-Fibroblasts|368C / Donor, Lineage, Cell class and subclass (all cells)

A2M CFH FMO2 PDGFRA LTBP1 SRPX CNN3

4.40e-071991047dbf64b83e2dc311b68f299c3f306ee098efd664c
ToppCellnormal_Lung-Fibroblasts|normal_Lung / Location, Cell class and cell subclass

A2M CFH FMO2 PDGFRA LTBP1 SRPX CNN3

4.56e-072001047803cf7f1382d07220249029cd220233232027689
ToppCell(5)_Fibroblasts|World / Lung cell shreds - cell class (v4) and cell subclass (v4)

A2M CFH FMO2 PDGFRA LTBP1 SRPX CNN3

4.56e-07200104722c839f27d3abdf86bfabdfa305f205dd899a9dc
ToppCellLPS_IL1RA-Mesenchymal_myocytic-Pericyte-Pericyte_2|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

COL4A2 NBEAL1 GAS6 MYO1B EGFL6 SRPX CNTN1

4.56e-072001047cf883ba5dbe6350b93142d625a52b25ff2a8bb63
ToppCell18-Airway-Mesenchymal|Airway / Age, Tissue, Lineage and Cell class

A2M PDGFRA EGFL6 TMEM47 SRPX CRISPLD1 CNN3

4.56e-072001047aca1e8def8ed6ae5749402d0288ad90656213de1
ToppCell390C-Fibroblasts|390C / Donor, Lineage, Cell class and subclass (all cells)

A2M CFH COL4A2 PDGFRA TMEM47 LTBP1 CNN3

4.56e-0720010473abe0f017fee6057ba73bd661a2bc8ec9e2bfe38
ToppCellParenchyma_Control_(B.)-Stromal-TX|Parenchyma_Control_(B.) / Sample group, Lineage and Cell type

A2M CFH COL4A2 FMO2 PDGFRA TMEM47 LTBP1

4.56e-0720010470a86656d48e4238d0e4d592d477d29f7ba7c2ec0
ToppCellLung_Parenchyma-Control-Mesenchymal-Mesenchymal|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

A2M CFH COL4A2 FMO2 PDGFRA TMEM47 LTBP1

4.56e-0720010473fa7d9ea67f9cc55478d085da53babd03dbe9bb1
ToppCellParenchymal-10x3prime_v2-Stromal-Fibroblastic-Fibro_myofibroblast|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

A2M CFH FMO2 PDGFRA GAS6 LTBP1 CNN3

4.56e-072001047251fd2923f108cd2086961d897244b392c32ad54
ToppCellParenchymal-10x3prime_v2-Stromal-Fibroblastic-Fibro_peribronchial|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

A2M CFH FMO2 PDGFRA TMEM47 PLPPR4 LTBP1

4.56e-072001047efdf7066b7dd43e35dbc0d2719b75f250cf54af2
ToppCellLung_Parenchyma-Control-Mesenchymal|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

A2M CFH COL4A2 FMO2 PDGFRA TMEM47 LTBP1

4.56e-0720010471e75d1302c22e1b1666c19c0c9259d5cc8be16d5
ToppCellBiopsy_Other_PF-Mesenchymal|Biopsy_Other_PF / Sample group, Lineage and Cell type

A2M CFH PDGFRA EGFL6 TMEM47 LTBP1 CNN3

4.56e-072001047d6fcdd48858b53b5a8d18ae14b2dc4d9af41b070
ToppCell367C-Fibroblasts|367C / Donor, Lineage, Cell class and subclass (all cells)

A2M CFH FMO2 PDGFRA TMEM47 LTBP1 CNN3

4.56e-072001047c5aaa20c59b9f11b8abdf5de9e3fc54f4e6e39f7
ToppCelldroplet-Lung-30m-Hematologic-myeloid-intermediate_monocyte-intermediate_monocyte_l4|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SEMA4D TBC1D2B TLR7 KDM6B CEACAM1 CTSS

2.59e-0616610461a3a15d1fc76bb91d832cdc6e3da0a6140b94b75
ToppCell356C-Fibroblasts-Fibroblast-H-|356C / Donor, Lineage, Cell class and subclass (all cells)

A2M COL4A2 PDGFRA TYRO3 LTBP1 HHIPL1

2.78e-061681046b5d74500bdac0d680ce7eb7afa0b867b8d85e6a4
ToppCell356C-Fibroblasts-Fibroblast-H|356C / Donor, Lineage, Cell class and subclass (all cells)

A2M COL4A2 PDGFRA TYRO3 LTBP1 HHIPL1

2.78e-061681046838ce47d4958ba12047882f97925eddd02f081c7
ToppCelldroplet-Lung-3m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l49|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CFH FMO2 ZC3HAV1L C4A C4B CRISPLD1

2.78e-061681046d2b91f2adc95dcfa623f8d7ca2df1c6f884da988
ToppCellAT1-AT2_cells-Donor_03|World / lung cells shred on cell class, cell subclass, sample id

COL4A2 FMO2 GAS6 LAMA3 PTPRF MARVELD2

2.88e-061691046815474855a70498a74e52f6583113c63b7267a0c
ToppCell390C-Lymphocytic-NK_cells-NK_cell_C|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

FMO2 KALRN LAIR2 HAVCR2 GUSB WNK3

2.98e-06170104681341bf4fe090af70b2091b6b2579ed08d76e22d
ToppCell5'-Adult-Appendix-Mesenchymal-fibroblastic-Stromal_1_(CCL11+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

A2M CFH COL4A2 PDGFRA CSMD3 CTNND2

3.40e-061741046f90ca117b729436cf452e2ddcec26ba525c5c13b
ToppCell356C-Epithelial_cells-Epithelial-G_(Club-Clara_cells)-|356C / Donor, Lineage, Cell class and subclass (all cells)

CFH FMO2 TFPI2 PTPRZ1 C4B MUC4

3.52e-061751046af9c5104c86231cfdb93a0f7d7032379efaa009e
ToppCell356C-Epithelial_cells-Epithelial-G_(Club-Clara_cells)|356C / Donor, Lineage, Cell class and subclass (all cells)

CFH FMO2 TFPI2 PTPRZ1 C4B MUC4

3.52e-0617510464bfae78ac3a2cb9404382aae96d291504a9cfa14
ToppCelldroplet-Lung-LUNG-30m-Epithelial|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ETV5 EGFL6 PTPRF PTPRZ1 LIPH IGSF1

3.63e-0617610465201f003192c033655ba47f0faf8c47a96eae03d
ToppCelltumor_Lymph_Node_/_Brain-Fibroblasts-COL13A1+_matrix_FBs|tumor_Lymph_Node_/_Brain / Location, Cell class and cell subclass

A2M CFH FMO2 PDGFRA PLPPR4 SRPX

3.63e-061761046510f9a14dc1c151d24d079e0cc004cdf4f86336c
ToppCell10x_3'_v2v3-Non-neoplastic-Myeloid-TAM-MG-TAM-MG_prolif-E|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

A2M GAS6 ETV5 SERPINB2 HHIPL1 CTSS

3.88e-06178104630d2b54462fd16222ad2e3806be6143e834b29e0
ToppCellIIH-matDC|IIH / Condition, Cell_class and T cell subcluster

FMO2 TFPI2 LTBP1 CRISPLD1 CNN3 CNTN1

4.01e-0617910465999c85ce3bab5309ff1ed154be7e32b037750b1
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_1-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

COL4A2 FMO2 GAS6 LAMA3 MYO1B CTNND2

4.01e-0617910464f6ca313b78aa93557937a046c44dcf8bcc9963c
ToppCellIIH-matDC-|IIH / Condition, Cell_class and T cell subcluster

FMO2 TFPI2 LTBP1 CRISPLD1 CNN3 CNTN1

4.01e-06179104646074b2781ed79e2979428b3ec81504621d3903c
ToppCellIPF-Epithelial-Mesothelial|IPF / Disease state, Lineage and Cell class

CFH TFPI2 NPAS3 SERPINB2 C4A C4B

4.14e-0618010461fa54bf4dba72866b2295639d991af639341bc08
ToppCell-Myositis-ILD_01|World / lung cells shred on cell class, cell subclass, sample id

PDGFRA TFPI2 EGFL6 SCN2A SERPINB2 WNK3

4.27e-061811046ef579e958f334da0f9415aa7e3d5c02c807954a6
ToppCellAT1-AT2_cells-Donor_05|World / lung cells shred on cell class, cell subclass, sample id

COL4A2 FMO2 GAS6 LAMA3 MYO1B PTPRF

4.27e-061811046ca23ce4f2c7b684d8ddd0e8619b3b696023d75e3
ToppCell390C-Fibroblasts-Fibroblast-A_(Fibroblast_progenitors)|390C / Donor, Lineage, Cell class and subclass (all cells)

A2M CFH PDGFRA TFPI2 SRPX CNN3

4.55e-06183104628e1fc6498aaf8f42c4d6d4fa54ffff4c546d0d1
ToppCell390C-Fibroblasts-Fibroblast-A_(Fibroblast_progenitors)-|390C / Donor, Lineage, Cell class and subclass (all cells)

A2M CFH PDGFRA TFPI2 SRPX CNN3

4.55e-061831046667d9107af17fd076ceff6b2cbcb78f892fd62d2
ToppCellAT1-AT2_cells-Donor_02|World / lung cells shred on cell class, cell subclass, sample id

COL4A2 FMO2 GAS6 LAMA3 PTPRF CTNND2

4.55e-0618310466821dca076318115d360ff426eb1218cfe104063
ToppCell5'-GW_trimst-2-LymphNode-Mesenchymal-fibroblastic-Stromal_3_(C7+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FMO2 GAS6 EGFL6 PLPPR4 SRPX CNTN1

4.69e-0618410464d4d8f3f44c67d74c57e7af7b7c158f0157b2f49
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_1-D122|Adult / Lineage, Cell type, age group and donor

COL4A2 FMO2 LAMA3 MYO1B LIPH CTNND2

4.69e-061841046561592edc3083fad41b91811151b442207c65dd9
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_1|Children_(3_yrs) / Lineage, Cell type, age group and donor

COL4A2 LAMA3 MYO1B PTPRF LIPH CTNND2

4.84e-0618510461c222f7285d6e3dae0354dc7e853ddc0ea55e63e
ToppCell(0)_MSCs|World / Cell class and subclass of bone marrow stroma cells in homeostatis

CFH FMO2 PDGFRA GAS6 C4B LTBP1

4.99e-061861046a832c1e0035bcd559722eccf262c145deb3494c7
ToppCell343B-Myeloid-Macrophage-M2-like_Macrophage_(MARCO_negative)|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

CFH FMO2 GAS6 NPAS3 ETV5 CLTC

4.99e-0618610469673367cb53bafb873a01ef6bda11d9f392ce648
ToppCellSmart-seq2-blood_(Smart-seq2)-myeloid-myeloid_monocytic-classical_monocyte|blood_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

MUC19 LAMA3 CSMD3 CNTN5 SCN2A CTSS

4.99e-06186104623b8d51d20b05795a73892d3e20e0f9b6a207820
ToppCell(2)_Fibroblasts-(20)_Fibro-1|(2)_Fibroblasts / Cell class and subclass of bone marrow stroma cells in homeostatis

COL4A2 PDGFRA GAS6 C4B LTBP1 SRPX

4.99e-061861046e93415b59dd89bc8a966dab0e0b65fe215933598
ToppCell(0)_MSCs-(00)_Lepr-MSC|World / Cell class and subclass of bone marrow stroma cells in homeostatis

CFH FMO2 PDGFRA GAS6 C4B LTBP1

4.99e-061861046f0d156167d7cc2cd8a76e5a364233e9f2170bc01
ToppCellCOPD-Epithelial-ATI|COPD / Disease state, Lineage and Cell class

COL4A2 FMO2 GAS6 LAMA3 MYO1B PTPRF

4.99e-061861046df0977f6f48a2d4e11b59971f098b01204242f0f
ToppCellMesenchymal_cells-Adipo-CAR|World / Lineage and Cell class

CFH FMO2 PDGFRA GAS6 C4B SRPX

4.99e-0618610466ca8ce7ced91d6308b7c056032ffec1b37c974bf
ToppCell(2)_5-FU-(2)_LEPR+_perivascular_cells_and_VE-Cad+_vascular_cells_(mixed)|(2)_5-FU / Stress and Cell class

CFH MLEC GAS6 C4B LTBP1 EMC2

5.15e-0618710466bbf0f7fe203274dae8d582652f35cd3187c0065
ToppCellControl-Epithelial-ATI|Control / Disease state, Lineage and Cell class

COL4A2 FMO2 GAS6 LAMA3 MYO1B PTPRF

5.15e-061871046fdd1c57b61ca9392ac27661a82729f37593df63c
ToppCellControl-Fibroblasts-Other_FB|Control / group, cell type (main and fine annotations)

A2M CFH PDGFRA NPAS3 PLPPR4 LTBP1

5.15e-061871046bd3739c4a52aa1ba5deffd778e113a9800f7e158
ToppCellIPF-Stromal-SMC|IPF / Disease state, Lineage and Cell class

COL4A2 KALRN EGFL6 TMEM47 C4B LTBP1

5.31e-061881046e98b24c0de41285f01f7ac194ff0a1b59fd5c333
ToppCellSevere_COVID-19-Epithelial-undefined_Epi|Severe_COVID-19 / Disease group,lineage and cell class (2021.01.30)

TFPI2 LAMA3 LIPH JCHAIN SERPINB2 MUC4

5.47e-0618910468cbd35320c7e7ff013ef0c0f13f8d875db1c53cd
ToppCelldroplet-Lung-18m-Mesenchymal-fibroblast|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CFH FMO2 PDGFRA GAS6 MYO1B C4B

5.47e-061891046e76dc36a01d8ad7590b3acc4c46abfcb76857448
ToppCellnormal_Lung-Fibroblasts-Undetermined|normal_Lung / Location, Cell class and cell subclass

A2M CFH FMO2 GAS6 LTBP1 CNN3

5.64e-06190104630d4658bcc6796f0cdf54cc029f4bb904b13ef66
ToppCelldroplet-Pancreas-Exocrine-24m-Mesenchymal-pancreatic_stellate_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CFH COL4A2 PDGFRA TFPI2 LTBP1 SRPX

5.64e-0619010468cb950effc449ae59a915132ecc079be54d1acfe
ToppCelldroplet-Pancreas-Exocrine-24m-Mesenchymal|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CFH COL4A2 PDGFRA TFPI2 LTBP1 SRPX

5.64e-0619010465dfbd064ab1f8a0b18b5975c47f8e79697f3db15
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_1-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

COL4A2 FMO2 LAMA3 MYO1B PTPRF CTNND2

5.64e-06190104630b50d183d7649146eb1e79b47ba897355f1998a
ToppCelldroplet-Lung-nan-18m-Mesenchymal-Adventitial_Fibroblast|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CFH FMO2 PDGFRA GAS6 C4B SRPX

5.64e-06190104697772e69e6f51ebffbb5433ca7b40f1048723220
ToppCelldroplet-Pancreas-Exocrine-24m-Mesenchymal-pancreatic_stellate_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CFH COL4A2 PDGFRA TFPI2 LTBP1 SRPX

5.64e-06190104617a73a658fb30a4322b31e38db7b240023738f29
ToppCelldroplet-Lung-nan-18m-Mesenchymal-adventitial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CFH FMO2 PDGFRA GAS6 C4B SRPX

5.64e-06190104672c2b824acdc43139e6635785df3ed3feb58ec46
Drugisoformononetin

CFH TYRO3 C4A

3.20e-0671043CID000003764
DiseaseCOVID-19 (is_implicated_in)

A2M CFH TLR7

5.25e-05211033DOID:0080600 (is_implicated_in)
DiseaseCentral hypothyroidism

TRHR IGSF1

7.21e-0541032C0271801
Diseasearterial stiffness measurement

COL4A2 NPAS3 ZMYM2 NOL10

7.57e-05641034EFO_0004517
Diseasemucinous adenocarcinoma (is_marker_for)

MUC4 MUC6

1.20e-0451032DOID:3030 (is_marker_for)
Diseasecontactin-1 measurement

MUC19 CNTN1

1.79e-0461032EFO_0020286
Diseaseage at diagnosis, coronary atherosclerosis measurement

COL4A2 HHIPL1

1.79e-0461032EFO_0004918, EFO_0007938
DiseaseComplement deficiency disease

CFH C4A C4B

2.09e-04331033C0272242
Diseaseperitonitis (biomarker_via_orthology)

A2M GUSB

2.51e-0471032DOID:8283 (biomarker_via_orthology)
Diseasesmoking status measurement, high density lipoprotein cholesterol measurement

ETV5 PTPRZ1

2.51e-0471032EFO_0004612, EFO_0006527
Diseasehepatitis A virus cellular receptor 2 measurement

CFH HAVCR2

3.33e-0481032EFO_0008151
Diseasetyrosine-protein kinase receptor TYRO3 measurement

CFH TYRO3

3.33e-0481032EFO_0020829
Disease2-hydroxystearate measurement

MUC19 CNTN1

4.28e-0491032EFO_0021059
Diseasesystemic lupus erythematosus (implicated_via_orthology)

TLR7 C4A C4B

4.61e-04431033DOID:9074 (implicated_via_orthology)
DiseaseThromboembolism

GAS6 LPA

7.78e-04121032C0040038
Diseaseangina pectoris

CFH COL4A2 NBEAL1 LPA

9.82e-041251034EFO_0003913
Diseasemembranous glomerulonephritis (biomarker_via_orthology)

A2M CFH

1.07e-03141032DOID:10976 (biomarker_via_orthology)
Diseasesystemic lupus erythematosus (is_implicated_in)

CFH C4A C4B

1.35e-03621033DOID:9074 (is_implicated_in)
Diseasenon-lobar intracerebral hemorrhage

COL4A2 NBEAL1 PTPRF

1.41e-03631033EFO_0010178
DiseaseAntibody Deficiency Syndrome

CFH C4A

1.59e-03171032C0003257
Diseaseadenosine monophosphate measurement

MYO1B CSMD3

1.78e-03181032EFO_0010454
Diseaserenal cell carcinoma (is_implicated_in)

HAVCR2 C4A C4B

1.83e-03691033DOID:4450 (is_implicated_in)
Diseasecerebral infarction (is_marker_for)

A2M LPA

1.99e-03191032DOID:3526 (is_marker_for)
Diseasecoagulation factor measurement

CFH CNTN1

2.20e-03201032EFO_0004634
Diseasetissue factor measurement

CFH CNTN1

2.43e-03211032EFO_0010623
Diseasecreatinine measurement

CFH COL4A2 TRHR ETV5 CELA2B LIPH LPA UMOD ASIC4 CTSS

2.53e-0399510310EFO_0004518
Diseaseanxiety disorder (implicated_via_orthology)

SCN2A NODAL

2.66e-03221032DOID:2030 (implicated_via_orthology)
DiseaseRenal glomerular disease

CREBBP UMOD

2.91e-03231032C0268731
DiseaseGlomerulopathy Assessment

CREBBP UMOD

2.91e-03231032C4521256
DiseaseImmunologic Deficiency Syndromes

CFH C4A

2.91e-03231032C0021051
DiseaseColorectal Carcinoma

KALRN TFPI2 MYO1B CSMD3 UQCRC2 CTNND2 NODAL CNTN1

3.23e-037021038C0009402
Diseaseunipolar depression

CFH ETV5 AK9 CSMD3 ZC3H7A ZBTB34 SP140L CNTN5 CTNND2 DNAH6 CNTN1

3.27e-03120610311EFO_0003761

Protein segments in the cluster

PeptideGeneStartEntry
ASKNYYPKQNARDYC

C2orf16

1386

Q68DN1
KAQRLRPLYQYVNYC

C16orf86

186

Q6ZW13
PYNRRCVNTFGSYYC

EGFL6

186

Q8IUX8
ENYGYRDTVVYQCNP

CSMD3

2831

Q7Z407
FACYYPRVEYGFQVK

C4B

1616

P0C0L5
GSPLKAQSYEYVYRC

AACS

411

Q86V21
FKYNLRVPYGANYSC

ADAM7

156

Q9H2U9
KQLCTIPRDAAYYSY

CREBBP

1216

Q92793
PGDVCYYASRNDKSY

COL4A2

1551

P08572
ALQLAYYRIYGQACA

CRAT

436

P43155
LRKCYFPYLENGYNQ

CFH

386

P08603
RYYATYINKDPGLCG

FLG

4026

P20930
ASNYADPYRQLQYCP

CTNND2

496

Q9UQB3
VRVNYKDRSPCYGYQ

A2M

421

P01023
YQCLAENKYGAIYAS

CNTN5

456

O94779
YCRDENSVPAAYYLR

NWD2

161

Q9ULI1
LDTLRIYYGNGCKYN

NBEAL1

1046

Q6ZS30
IYYGNGCKYNELSLD

NBEAL1

1051

Q6ZS30
AYRNALANPLYCPDY

UQCRC2

181

P22695
YYNIGNYTQAVECAK

P3H1

311

Q32P28
CLNNKYSEGYPGKRY

SHMT2

91

P34897
YCFYGDLVNYLHKNR

PDGFRA

676

P16234
RCDGYKGYDLVYSPQ

MUC4

5301

Q99102
PAPFYKRCVYQACNY

MUC6

611

Q6W4X9
NCEQCAKGYYRPYGV

LAMA3

401

Q16787
YRGCEYPNLNGLYIF

HHIPL1

481

Q96JK4
VKGYYDNPKVCALYI

MLEC

196

Q14165
IAYQGRVKDEPAYYC

KDM6B

1561

O15054
YGQELLCYKYRGPES

KPTN

331

Q9Y664
YCKQGTYYDPVKLQC

LTBP1

1451

Q14766
RKPNLCPVYCDYYNA

MUC19

1531

Q7Z5P9
YCQNKPRSEYIVAEY

KALRN

2021

O60229
CNVKYAYEYLGNSPR

DNAH12

1211

Q6ZR08
QALGANYGEKCLYNY

ETV5

106

P41161
TAYPCDSYQDYRNGK

LIPH

266

Q8WWY8
YTRYGKCYTFNADPR

ASIC4

196

Q96FT7
YFQLRLNQPYCGYAV

NLRX1

321

Q86UT6
GTYKPRVRCYDTYQL

NOL10

71

Q9BSC4
NYVDGYNRPKAYIAA

PTPRZ1

1786

P23471
KIPGYRVGCYYCLFQ

C17orf75

116

Q9HAS0
SKYIYDQCPAVAGYG

UQCRC1

446

P31930
GKIYHPSCYEDYQNT

PCF11

1471

O94913
YKCLQIELSRGYNYD

DNAH6

2466

Q9C0G6
IGNYSCSYRLQAYPD

IGSF1

1221

Q8N6C5
LGCNYYYKPSIFTRV

CELA2B

241

P08218
DTYYRPGANLSLSCY

CEACAM1

246

P13688
RENLCYKEGSDRYYP

CRISPLD1

236

Q9H336
RYLDCINKYGSPYTK

GAS6

91

Q14393
KGAPYVDVICLNSYY

GUSB

491

P08236
QKDAGIYYCLASNNY

CNTN1

106

Q12860
EYYPNAGLIMNYCRN

LPA

521

P08519
PAYYPNAGLIKNYCR

LPA

976

P08519
YYPNAGLTRNYCRNP

LPA

1426

P08519
YVNDTNRGGLCYYPL

MARVELD2

311

Q8N4S9
VRLYFGPCNSYQYRL

FMO2

461

Q99518
LYRSGVYYEPSCTQN

CTSS

261

P25774
CEYLNAYSGRKYQAD

CENPO

181

Q9BU64
YDRNKCYTAVVPLVY

JCHAIN

126

P01591
YCQQYAEVKYTQGGL

EMC2

191

Q15006
YPVKKCQERDFQYGY

GTDC1

96

Q4AE62
FACYYPRVEYGFQVK

C4A

1616

P0C0L4
VSEGNAGLYRCLYYK

LAIR2

91

Q6ISS4
DQYQLCYRAALEYLG

PTPRF

1886

P10586
YIRLCQKYYSSEPQA

SERPINB2

141

P05120
GRAYYLQLCTSAYKQ

GARIN2

146

Q8N9W8
QGYCPVTYKDGNQRY

AK9

1726

Q5TCS8
VISCGYKISRNYYSP

TRHR

176

P34981
IYPKQYNAYRCEGEC

NODAL

266

Q96S42
YRAEVGQNAYLPCFY

HAVCR2

26

Q8TDQ0
SEGLKLYYNPYTGCI

SHPRH

341

Q149N8
NQSECRKIYRYDGIY

NPAS3

26

Q8IXF0
FFYNCYKGYLPRQCL

SEMA4D

751

Q92854
DVYCRAPQGGYYKTA

SRPX

66

P78539
PYYYYIREACQGLKE

SP140L

496

Q9H930
VEGDYTYLRINFYCP

SUPT16H

561

Q9Y5B9
ENPYYDSRVVGKYCE

CLTC

896

Q00610
YGLGRQVYDPKYCAA

CNN3

261

Q15417
QYYAYTQFCLPGSAR

PIGV

256

Q9NUD9
GYQAPYFLTVCKPNY

PLPPR4

201

Q7Z2D5
SVQVKACAGGYYVYN

UMOD

261

P07911
AYAYRNPKIGYCQAM

TBC1D8B

561

Q0IIM8
RAQKYCKYAGSALQY

VTA1

271

Q9NP79
AYTLYRPEQGYCQAQ

TBC1D10C

166

Q8IV04
YICVKAGRNPNYGYT

SCN2A

351

Q99250
KFPRCAEGYALYAQA

TOMM70

471

O94826
GAILYCLNPKNYEDY

TMEM47

166

Q9BQJ4
GTAIDCYKYLEPLYN

PRPF38A

111

Q8NAV1
ILYLGQNCYYRNPCY

TLR7

176

Q9NYK1
PYECKQCGKAFRYYQ

ZNF709

251

Q8N972
KACNNYQYGYLAKPD

nan

101

Q8IYB0
NYAPDSIYYLCLGIQ

ZMYM2

1136

Q9UBW7
KTNYEGPYYICKDVA

ZC3H7A

496

Q8IWR0
TGEKPYQCQYCEYRS

ZFX

571

P17010
SNRQKTPYEGNYYKC

ZNF484

316

Q5JVG2
YNDNFFGLYCICKRP

UBR7

126

Q8N806
YNCEICGNYTYRGPK

SF3A3

406

Q12874
LCSANVTRYYFNPRY

TFPI2

166

P48307
LCRQNNLYVQPYACY

TTC39C

516

Q8N584
NLYVQPYACYELGCL

TTC39C

521

Q8N584
RDPGRDYELYKYTCQ

THOC5

46

Q13769
CPEYLVDYLENYGRK

USP2

191

O75604
YTLYRPEEGYCQAQA

TBC1D10A

186

Q9BXI6
DARRCYLYYFKSPQD

TBC1D2B

61

Q9UPU7
YSGDYYRQGCASKLP

TYRO3

681

Q06418
NLKVRNAGEYTCEYY

TARM1

86

B6A8C7
NAGEYTCEYYRKASP

TARM1

91

B6A8C7
YPYNERLICIYCGKS

ZBTB34

366

Q8NCN2
LYNKGEALYGYCNLK

ZC3HAV1L

171

Q96H79
YPYSECQNAAQIYRK

WNK3

346

Q9BYP7
YDNANIYSRTREYCP

LRIG2

906

O94898
GYAFRQAYEPCLERY

MYO1B

631

O43795