Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionribose phosphate diphosphokinase activity

PRPS2 PRPS1L1 PRPS1

3.71e-0651453GO:0004749
GeneOntologyMolecularFunctionethanol binding

ADH1A ADH1B ADH1C

7.38e-0661453GO:0035276
GeneOntologyMolecularFunctiondiphosphotransferase activity

PRPS2 PRPS1L1 PRPS1

7.38e-0661453GO:0016778
GeneOntologyMolecularFunctionendopeptidase activity

PRSS3 KLK6 TMPRSS11E ADAMTS8 ADAMTS12 USP8 USP5 CNTNAP5 SENP6 ERVK-19 ERVK-25 SENP7

7.30e-0543014512GO:0004175
GeneOntologyMolecularFunctionlow-density lipoprotein particle receptor activity

STAB2 LRP1B SORL1

1.96e-04161453GO:0005041
GeneOntologyMolecularFunctionactin filament binding

MYO1G MYH3 MYO1C CORO2A SPTB SPTBN1 LRPPRC CORO2B

2.58e-042271458GO:0051015
GeneOntologyMolecularFunctionAMP binding

PRPS2 FBP1 PRPS1

4.53e-04211453GO:0016208
GeneOntologyMolecularFunctionlipoprotein particle receptor activity

STAB2 LRP1B SORL1

4.53e-04211453GO:0030228
GeneOntologyMolecularFunctionubiquitin-like protein-specific endopeptidase activity

SENP6 SENP7

5.16e-0451452GO:0070137
GeneOntologyMolecularFunctionSUMO-specific endopeptidase activity

SENP6 SENP7

5.16e-0451452GO:0070139
GeneOntologyMolecularFunctionankyrin binding

SPTB SPTBN1 KCNQ2

5.97e-04231453GO:0030506
GeneOntologyMolecularFunctionall-trans-retinol dehydrogenase (NAD+) activity

ADH1A ADH1B ADH1C

6.79e-04241453GO:0004745
GeneOntologyMolecularFunctionalcohol dehydrogenase (NAD+) activity

ADH1A ADH1B ADH1C

8.63e-04261453GO:0004022
GeneOntologyMolecularFunctionpeptidase activity

PRSS3 KLK6 NPEPPS TMPRSS11E ADAMTS8 ADAMTS12 USP8 USP5 CNTNAP5 SENP6 ERVK-19 ERVK-25 SENP7

9.79e-0465414513GO:0008233
GeneOntologyMolecularFunctionalcohol dehydrogenase [NAD(P)+] activity

ADH1A ADH1B ADH1C

1.32e-03301453GO:0018455
GeneOntologyBiologicalProcessacetaldehyde biosynthetic process

ADH1A ADH1B ADH1C

3.06e-0731403GO:0046186
GeneOntologyBiologicalProcessacetaldehyde metabolic process

ADH1A ADH1B ADH1C

3.03e-0651403GO:0006117
GeneOntologyBiologicalProcess5-phosphoribose 1-diphosphate metabolic process

PRPS2 PRPS1L1 PRPS1

6.03e-0661403GO:0046391
GeneOntologyBiologicalProcess5-phosphoribose 1-diphosphate biosynthetic process

PRPS2 PRPS1L1 PRPS1

6.03e-0661403GO:0006015
GeneOntologyCellularComponentribose phosphate diphosphokinase complex

PRPS2 PRPS1L1 PRPS1

3.24e-0651453GO:0002189
MousePhenoabnormal ethanol metabolism

ADH1A ADH1B ADH1C

7.42e-0661023MP:0005443
MousePhenoabnormal retinol metabolism

ADH1A ADH1B ADH1C

1.29e-0571023MP:0005444
DomainPRPP_SYNTHASE

PRPS2 PRPS1L1 PRPS1

4.21e-0731413PS00114
DomainPRib_PP_synth_CS

PRPS2 PRPS1L1 PRPS1

4.21e-0731413IPR000842
DomainCRAL/TRIO_N_dom

MOSPD2 SEC14L3 SEC14L6 SEC14L4

3.98e-06151414IPR011074
DomainPribosyltran_N

PRPS2 PRPS1L1 PRPS1

4.17e-0651413PF13793
DomainPribosyl_synth

PRPS2 PRPS1L1 PRPS1

4.17e-0651413PF14572
DomainRib-P_diPkinase

PRPS2 PRPS1L1 PRPS1

4.17e-0651413IPR005946
DomainPribosyltran_N

PRPS2 PRPS1L1 PRPS1

4.17e-0651413IPR029099
DomainCRAL_TRIO

MOSPD2 SEC14L3 SEC14L6 SEC14L4

1.69e-05211414PF00650
DomainADH_Zn_CS

ADH1A ADH1B ADH1C

2.29e-0581413IPR002328
DomainADH_ZINC

ADH1A ADH1B ADH1C

2.29e-0581413PS00059
Domain-

MOSPD2 SEC14L3 SEC14L6 SEC14L4

2.47e-052314143.40.525.10
DomainSEC14

MOSPD2 SEC14L3 SEC14L6 SEC14L4

3.48e-05251414SM00516
DomainCRAL_TRIO

MOSPD2 SEC14L3 SEC14L6 SEC14L4

4.77e-05271414PS50191
DomainCRAL-TRIO_dom

MOSPD2 SEC14L3 SEC14L6 SEC14L4

5.54e-05281414IPR001251
DomainPribosyltran

PRPS2 PRPS1L1 PRPS1

6.65e-05111413PF00156
DomainCRAL-bd_toc_tran

SEC14L3 SEC14L6 SEC14L4

8.82e-05121413IPR001071
DomainPRTase-like

PRPS2 PRPS1L1 PRPS1

8.82e-05121413IPR029057
DomainPRibTrfase_dom

PRPS2 PRPS1L1 PRPS1

8.82e-05121413IPR000836
Domain-

PRPS2 PRPS1L1 PRPS1

8.82e-051214133.40.50.2020
DomainCRAL_TRIO_N

SEC14L3 SEC14L6 SEC14L4

8.82e-05121413SM01100
DomainPOLO_box_2

PLK1 PLK3

1.69e-0431412IPR033695
DomainLY

LRP1B ROS1 SORL1

1.79e-04151413SM00135
DomainLDLR_classB_rpt

LRP1B ROS1 SORL1

1.79e-04151413IPR000033
DomainPKS_ER

ADH1A ADH1B ADH1C

2.19e-04161413IPR020843
DomainADH_N

ADH1A ADH1B ADH1C

2.19e-04161413PF08240
DomainPKS_ER

ADH1A ADH1B ADH1C

2.19e-04161413SM00829
DomainADH_N

ADH1A ADH1B ADH1C

2.19e-04161413IPR013154
Domain-

ADH1A ADH1B ADH1C

3.16e-041814133.90.180.10
Domain-

PLK1 PLK3

3.36e-04414123.30.1120.30
DomainPOLO_box

PLK1 PLK3

3.36e-0441412PF00659
DomainPOLO_box_1

PLK1 PLK3

3.36e-0441412IPR033701
DomainSpectrin_bsu

SPTB SPTBN1

3.36e-0441412IPR016343
DomainPOLO_BOX

PLK1 PLK3

3.36e-0441412PS50078
DomainGOLD_dom

SEC14L3 SEC14L6 SEC14L4

3.74e-04191413IPR009038
DomainADH_zinc_N

ADH1A ADH1B ADH1C

3.74e-04191413PF00107
DomainADH_SF_Zn-type

ADH1A ADH1B ADH1C

3.74e-04191413IPR002085
DomainADH_C

ADH1A ADH1B ADH1C

3.74e-04191413IPR013149
DomainGOLD

SEC14L3 SEC14L6 SEC14L4

3.74e-04191413PS50866
DomainNUT

NUTM2G NUTM2F

5.58e-0451412IPR024310
DomainNUT_N

NUTM2G NUTM2F

5.58e-0451412IPR024309
DomainNUT

NUTM2G NUTM2F

5.58e-0451412PF12881
DomainPOLO_box_dom

PLK1 PLK3

5.58e-0451412IPR000959
DomainSortilin_C

SORCS1 SORL1

5.58e-0451412PF15901
DomainSortilin-Vps10

SORCS1 SORL1

5.58e-0451412PF15902
DomainVPS10

SORCS1 SORL1

5.58e-0451412IPR006581
DomainSortilin_N

SORCS1 SORL1

5.58e-0451412IPR031778
DomainSortilin_C

SORCS1 SORL1

5.58e-0451412IPR031777
DomainVPS10

SORCS1 SORL1

5.58e-0451412SM00602
DomainGroES-like

ADH1A ADH1B ADH1C

7.59e-04241413IPR011032
DomainTumour_necrosis_fac-like_dom

SEC14L3 MMRN2 C1QB SEC14L4

9.63e-04581414IPR008983
DomainEGF_extracell

STAB2 LRP1B SVEP1 ATRNL1

1.09e-03601414IPR013111
DomainEGF_2

STAB2 LRP1B SVEP1 ATRNL1

1.09e-03601414PF07974
DomainTrimer_CC

CORO2A CORO2B

1.16e-0371412IPR015049
DomainDUF1899

CORO2A CORO2B

1.16e-0371412IPR015048
DomainTrimer_CC

CORO2A CORO2B

1.16e-0371412PF08954
DomainDUF1899

CORO2A CORO2B

1.16e-0371412PF08953
DomainPeptidase_C48_C

SENP6 SENP7

1.16e-0371412IPR003653
DomainCoronin

CORO2A CORO2B

1.16e-0371412IPR015505
DomainPeptidase_C48

SENP6 SENP7

1.16e-0371412PF02902
DomainMyosin_TH1

MYO1G MYO1C

1.16e-0371412PF06017
DomainMyosin_TH1

MYO1G MYO1C

1.16e-0371412IPR010926
DomainDUF1899

CORO2A CORO2B

1.16e-0371412SM01166
DomainTH1

MYO1G MYO1C

1.16e-0371412PS51757
DomainULP_PROTEASE

SENP6 SENP7

1.16e-0371412PS50600
Domainfn3

NPHS1 EPHA6 ROS1 IGSF9B CDON SORL1

1.45e-031621416PF00041
DomainSialidases

SORCS1 SORL1

1.97e-0391412IPR011040
DomainEGF

STAB2 LRP1B SVEP1 GPR179 CNTNAP5 ATRNL1 SORL1

2.07e-032351417SM00181
DomainFN3

NPHS1 EPHA6 ROS1 IGSF9B CDON SORL1

2.83e-031851416SM00060
DomainMyosin_head_motor_dom

MYO1G MYH3 MYO1C

2.93e-03381413IPR001609
DomainMYOSIN_MOTOR

MYO1G MYH3 MYO1C

2.93e-03381413PS51456
DomainMyosin_head

MYO1G MYH3 MYO1C

2.93e-03381413PF00063
DomainMYSc

MYO1G MYH3 MYO1C

2.93e-03381413SM00242
DomainGFP-like

STAB2 SVEP1

2.98e-03111412IPR023413
Domain-

STAB2 SVEP1

2.98e-031114122.40.155.10
DomainCRAL_TRIO_N

SEC14L3 SEC14L4

2.98e-03111412PF03765
Domain-

LRP1B ROS1 SORL1

3.16e-033914132.120.10.30
PathwayREACTOME_ABACAVIR_ADME

ADH1A ADH1B ADH1C

2.01e-0581023MM14869
PathwayKEGG_PENTOSE_PHOSPHATE_PATHWAY

PRPS2 PRPS1L1 FBP1 PRPS1

3.99e-05271024M1386
PathwayWP_FATTY_ACID_OMEGAOXIDATION

ADH1A ADH1B ADH1C

4.25e-05101023MM15833
PathwayREACTOME_ETHANOL_OXIDATION

ADH1A ADH1B ADH1C

5.82e-05111023MM15405
PathwayREACTOME_ETHANOL_OXIDATION

ADH1A ADH1B ADH1C

7.72e-05121023M14663
PathwayWP_FATTY_ACID_OMEGAOXIDATION

ADH1A ADH1B ADH1C

1.57e-04151023M39717
PathwayREACTOME_PENTOSE_PHOSPHATE_PATHWAY

PRPS2 PRPS1L1 PRPS1

1.57e-04151023M27682
PathwayREACTOME_PENTOSE_PHOSPHATE_PATHWAY

PRPS2 PRPS1L1 PRPS1

1.57e-04151023MM15404
PathwayWP_RETINOL_METABOLISM

RARB ADH1A ADH1B ADH1C

2.81e-04441024MM15851
PathwayREACTOME_SIGNALING_BY_RETINOIC_ACID

RARB ADH1A ADH1B ADH1C

4.26e-04491024MM15186
Pubmed

Isolation of genomic DNA fragments corresponding to genes modulated in vivo by a transcription factor.

ADH1A ADH1B ADH1C KNG1

2.17e-08814847937138
Pubmed

Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.

PRSS3 RARB CORO2A SPTB SPTBN1 NCAPH2 ADAMTS8 ZNF227 KANK2 LRP1B USP8 UBE2O PTPN13 CORO2B LMO7 CTR9 ATRNL1 SENP6 KCNQ2 ZNF76 PAX6 TNKS2

2.91e-0812851482235914814
Pubmed

Retinol/ethanol drug interaction during acute alcohol intoxication in mice involves inhibition of retinol metabolism to retinoic acid by alcohol dehydrogenase.

ADH1A ADH1B ADH1C

7.55e-083148311960985
Pubmed

Tissue-specific genetic variation in the level of mouse alcohol dehydrogenase is controlled transcriptionally in kidney and posttranscriptionally in liver.

ADH1A ADH1B ADH1C

7.55e-08314832474823
Pubmed

Chromosomal assignment of the alcohol dehydrogenase cluster locus to human chromosome 4q21-23 by in situ hybridization.

ADH1A ADH1B ADH1C

7.55e-08314832737681
Pubmed

Regulation of human class I alcohol dehydrogenases by bile acids.

ADH1A ADH1B ADH1C

7.55e-083148323772048
Pubmed

A negative regulatory element upstream from the mouse Adh-1 gene can down-regulate a heterologous promoter.

ADH1A ADH1B ADH1C

7.55e-08314838163197
Pubmed

Promoter regions of the human X-linked housekeeping genes PRPS1 and PRPS2 encoding phosphoribosylpyrophosphate synthetase subunit I and II isoforms.

PRPS2 PRPS1L1 PRPS1

7.55e-08314831314091
Pubmed

ALDH expression characterizes G1-phase proliferating beta cells during pregnancy.

ADH1A ADH1B ADH1C

7.55e-083148324787690
Pubmed

Androgen induction of alcohol dehydrogenase in mouse kidney. Studies with a cDNA probe confirmed by nucleotide sequence analysis.

ADH1A ADH1B ADH1C

7.55e-08314833011597
Pubmed

Alcohol dehydrogenase isozymes in the mouse: genetic regulation, allelic variation among inbred strains and sex differences of liver and kidney A2 isozyme activity.

ADH1A ADH1B ADH1C

7.55e-08314836756216
Pubmed

Alcohol dehydrogenase 1 is a tubular mitophagy-dependent apoptosis inhibitor against septic acute kidney injury.

ADH1A ADH1B ADH1C

7.55e-083148337806378
Pubmed

Structure and function of a long alternating purine-pyrimidine sequence in the mouse alcohol dehydrogenase Adh-1 gene.

ADH1A ADH1B ADH1C

7.55e-08314837840644
Pubmed

Alcoholic fatty liver: its pathogenesis and mechanism of progression to inflammation and fibrosis.

ADH1A ADH1B ADH1C

7.55e-083148315670660
Pubmed

Stage and tissue-specific expression of the alcohol dehydrogenase 1 (Adh-1) gene during mouse development.

ADH1A ADH1B ADH1C

7.55e-08314838018987
Pubmed

Paracardial fat remodeling affects systemic metabolism through alcohol dehydrogenase 1.

ADH1A ADH1B ADH1C

7.55e-083148333586683
Pubmed

Cloning and sequencing of cDNA encoding the complete mouse liver alcohol dehydrogenase.

ADH1A ADH1B ADH1C

7.55e-08314833157987
Pubmed

Promoters for the human alcohol dehydrogenase genes ADH1, ADH2, and ADH3: interaction of CCAAT/enhancer-binding protein with elements flanking the ADH2 TATA box.

ADH1A ADH1B ADH1C

7.55e-08314832169444
Pubmed

A novel negative element in the promoter of the mouse alcohol dehydrogenase gene Adh-1.

ADH1A ADH1B ADH1C

7.55e-08314838486690
Pubmed

Individual susceptibility and alcohol effects:biochemical and genetic aspects.

ADH1A ADH1B ADH1C

7.55e-083148316801720
Pubmed

Recommended nomenclature for the vertebrate alcohol dehydrogenase gene family.

ADH1A ADH1B ADH1C

7.55e-083148310424757
Pubmed

The human class I alcohol dehydrogenase gene cluster: three genes are tandemly organized in an 80-kb-long segment of the genome.

ADH1A ADH1B ADH1C

7.55e-08314832347582
Pubmed

Beneficial effect of low ethanol intake on the cardiovascular system: possible biochemical mechanisms.

ADH1A ADH1B ADH1C

7.55e-083148317326332
Pubmed

The role of alcohol dehydrogenase in retinoic acid homeostasis and fetal alcohol syndrome.

ADH1A ADH1B ADH1C

7.55e-08314837748347
Pubmed

Genetics of human alcohol and aldehyde dehydrogenases.

ADH1A ADH1B ADH1C

7.55e-08314833006456
Pubmed

Short-term selective breeding as a tool for QTL mapping: ethanol preference drinking in mice.

ADH1A ADH1B ADH1C

7.55e-08314839145544
Pubmed

Structure of the mouse Adh-1 gene and identification of a deletion in a long alternating purine-pyrimidine sequence in the first intron of strains expressing low alcohol dehydrogenase activity.

ADH1A ADH1B ADH1C

7.55e-08314833428612
Pubmed

Genetic and developmental regulation of mouse liver alcohol dehydrogenase.

ADH1A ADH1B ADH1C

7.55e-08314836816803
Pubmed

Ten kilobases of 5'-flanking region confers proper regulation of the mouse alcohol dehydrogenase-1 (Adh-1) gene in kidney and adrenal of transgenic mice.

ADH1A ADH1B ADH1C

7.55e-08314838973327
Pubmed

The discovery of the microsomal ethanol oxidizing system and its physiologic and pathologic role.

ADH1A ADH1B ADH1C

7.55e-083148315554233
Pubmed

ADH1C inhibits progression of colorectal cancer through the ADH1C/PHGDH /PSAT1/serine metabolic pathway.

ADH1A ADH1B ADH1C

7.55e-083148335354963
Pubmed

Purification and characterization of mouse alcohol dehydrogenase from two inbred strains that differ in total liver enzyme activity.

ADH1A ADH1B ADH1C

7.55e-08314836370228
Pubmed

Three human alcohol dehydrogenase subunits: cDNA structure and molecular and evolutionary divergence.

ADH1A ADH1B ADH1C

7.55e-08314832935875
Pubmed

Genetic regulation of gene-specific mRNA by ethanol in vivo and its possible role in ethanol preference in a cross with RI lines in mice.

ADH1A ADH1B ADH1C

3.01e-07414838813054
Pubmed

Distribution of class I, III and IV alcohol dehydrogenase mRNAs in the adult rat, mouse and human brain.

ADH1A ADH1B ADH1C

3.01e-074148312631290
Pubmed

Molecular analysis of mouse alcohol dehydrogenase: nucleotide sequence of the Adh-1 gene and genetic mapping of a related nucleotide sequence to chromosome 3.

ADH1A ADH1B ADH1C

3.01e-07414832893758
Pubmed

Overexpression of alcohol dehydrogenase exacerbates ethanol-induced contractile defect in cardiac myocytes.

ADH1A ADH1B ADH1C

3.01e-074148311893554
Pubmed

Metabolic pharmacokinetics of early chronic alcohol consumption mediated by liver alcohol dehydrogenases 1 and 3 in mice.

ADH1A ADH1B ADH1C

3.01e-074148329663519
Pubmed

Genetic evidence that retinaldehyde dehydrogenase Raldh1 (Aldh1a1) functions downstream of alcohol dehydrogenase Adh1 in metabolism of retinol to retinoic acid.

ADH1A ADH1B ADH1C

3.01e-074148312851412
Pubmed

ADH1 and ADH4 alcohol/retinol dehydrogenases in the developing adrenal blastema provide evidence for embryonic retinoid endocrine function.

ADH1A ADH1B ADH1C

3.01e-07414839733106
Pubmed

Hepatic CYP2B10 is highly induced by binge ethanol and contributes to acute-on-chronic alcohol-induced liver injury.

ADH1A ADH1B ADH1C

3.01e-074148336224745
Pubmed

Retinoic acid and alcohol/retinol dehydrogenase in the mouse adrenal gland: a potential endocrine source of retinoic acid during development.

ADH1A ADH1B ADH1C

3.01e-07414839202249
Pubmed

Effects of polymorphisms in untranslated regions of the class I alcohol dehydrogenase (ADH) genes on alcohol metabolism in Japanese subjects and transcriptional activity in HepG2 cells.

ADH1A ADH1B ADH1C

3.01e-074148319618839
Pubmed

Mouse mitochondrial aldehyde dehydrogenase isozymes: purification and molecular properties.

ADH1A ADH1B ADH1C

3.01e-07414833996732
Pubmed

Genetic mapping of a possible new alcohol dehydrogenase sequence to mouse chromosome 3 at the Adh-1/Adh-3 complex.

ADH1A ADH1B ADH1C

3.01e-07414839241435
Pubmed

Families of retinoid dehydrogenases regulating vitamin A function: production of visual pigment and retinoic acid.

ADH1A ADH1B ADH1C

3.01e-074148310880953
Pubmed

Localization of class I and class IV alcohol dehydrogenases in mouse testis and epididymis: potential retinol dehydrogenases for endogenous retinoic acid synthesis.

ADH1A ADH1B ADH1C

3.01e-07414839002638
Pubmed

Opposing actions of cellular retinol-binding protein and alcohol dehydrogenase control the balance between retinol storage and degradation.

ADH1A ADH1B ADH1C

3.01e-074148315193143
Pubmed

Contribution of cellular retinol-binding protein type 1 to retinol metabolism during mouse development.

RARB ADH1A ADH1B ADH1C

5.51e-0716148415765518
Pubmed

Distinct retinoid metabolic functions for alcohol dehydrogenase genes Adh1 and Adh4 in protection against vitamin A toxicity or deficiency revealed in double null mutant mice.

ADH1A ADH1B ADH1C

7.50e-075148311836246
Pubmed

Retinoic acid synthesis in mouse embryos during gastrulation and craniofacial development linked to class IV alcohol dehydrogenase gene expression.

ADH1A ADH1B ADH1C

7.50e-07514838621625
Pubmed

Assignment of the rat genes coding for alpha 1-antitrypsin (PI), phosphoenolpyruvate carboxykinase (PEPCK), alcohol dehydrogenase (ADH), and fructose-1,6-bisphosphatase (FDP).

ADH1A ADH1B ADH1C

7.50e-07514831316195
Pubmed

Cloning of the mouse class IV alcohol dehydrogenase (retinol dehydrogenase) cDNA and tissue-specific expression patterns of the murine ADH gene family.

ADH1A ADH1B ADH1C

7.50e-07514837738026
Pubmed

Expression patterns of class I and class IV alcohol dehydrogenase genes in developing epithelia suggest a role for alcohol dehydrogenase in local retinoic acid synthesis.

ADH1A ADH1B ADH1C

7.50e-07514838892527
Pubmed

Mouse alcohol dehydrogenase isozymes: products of closely localized duplicate genes exhibiting divergent kinetic properties.

ADH1A ADH1B ADH1C

7.50e-07514837026729
Pubmed

ADH single nucleotide polymorphism associations with alcohol metabolism in vivo.

ADH1A ADH1B ADH1C

7.50e-075148319193628
Pubmed

Adh1 and Adh1/4 knockout mice as possible rodent models for presymptomatic Parkinson's disease.

ADH1A ADH1B ADH1C

7.50e-075148322079585
Pubmed

Metabolic deficiencies in alcohol dehydrogenase Adh1, Adh3, and Adh4 null mutant mice. Overlapping roles of Adh1 and Adh4 in ethanol clearance and metabolism of retinol to retinoic acid.

ADH1A ADH1B ADH1C

7.50e-075148310358022
Pubmed

High and complementary expression patterns of alcohol and aldehyde dehydrogenases in the gastrointestinal tract: implications for Parkinson's disease.

ADH1A ADH1B ADH1C

1.50e-066148317257171
Pubmed

Alcohol Dehydrogenase Protects against Endoplasmic Reticulum Stress-Induced Myocardial Contractile Dysfunction via Attenuation of Oxidative Stress and Autophagy: Role of PTEN-Akt-mTOR Signaling.

ADH1A ADH1B ADH1C

1.50e-066148326807981
Pubmed

Excessive vitamin A toxicity in mice genetically deficient in either alcohol dehydrogenase Adh1 or Adh3.

ADH1A ADH1B ADH1C

1.50e-066148312027900
Pubmed

Merging protein, gene and genomic data: the evolution of the MDR-ADH family.

ADH1A ADH1B ADH1C

1.50e-066148316121213
Pubmed

Human liver alcohol dehydrogenase: purification, composition, and catalytic features.

ADH1A ADH1B ADH1C

1.50e-06614839982
Pubmed

Genetics and ontogeny of alcohol dehydrogenase isozymes in the mouse: evidence for a cis-acting regulator gene (Adt-i) controlling C2 isozyme expression in reproductive tissues and close linkage of Adh-3 and Adt-i on chromosome 3.

ADH1A ADH1B ADH1C

1.50e-0661483518534
Pubmed

Multiple ADH genes modulate risk for drug dependence in both African- and European-Americans.

ADH1A ADH1B ADH1C

1.50e-066148317185388
Pubmed

Large-scale proteomics and phosphoproteomics of urinary exosomes.

NPHS1 MYH3 MYO1C NPEPPS SPTBN1 ITGA1 GPRC5A BROX PTPN13 FBP1 SMPDL3B GLB1 MTHFD1 MMRN2 PLEKHA1 KNG1 SORL1

1.69e-0610161481719056867
Pubmed

Identification of endogenous retinoids, enzymes, binding proteins, and receptors during early postimplantation development in mouse: important role of retinal dehydrogenase type 2 in synthesis of all-trans-retinoic acid.

RARB ADH1A ADH1B ADH1C

2.17e-0622148410753524
Pubmed

Diplotype trend regression analysis of the ADH gene cluster and the ALDH2 gene: multiple significant associations with alcohol dependence.

ADH1A ADH1B ADH1C

2.61e-067148316685648
Pubmed

Extended genetic effects of ADH cluster genes on the risk of alcohol dependence: from GWAS to replication.

ADH1A ADH1B ADH1C

2.61e-067148323456092
Pubmed

Association between common alcohol dehydrogenase gene (ADH) variants and schizophrenia and autism.

ADH1A ADH1B ADH1C

2.61e-067148323468174
Pubmed

Tissue- and species-specific expression patterns of class I, III, and IV Adh and Aldh 1 mRNAs in rodent embryos.

ADH1A ADH1B ADH1C

2.61e-067148316047160
Pubmed

Organization of six functional mouse alcohol dehydrogenase genes on two overlapping bacterial artificial chromosomes.

ADH1A ADH1B ADH1C

2.61e-067148311784316
Pubmed

Androgen regulation of gene expression in primary epithelial cells of the mouse kidney.

ADH1A ADH1B ADH1C

2.61e-06714838119157
Pubmed

STOmicsDB: a comprehensive database for spatial transcriptomics data sharing, analysis and visualization.

ADH1A ADH1B ADH1C

2.61e-067148337953328
Pubmed

Association of ADH and ALDH genes with alcohol dependence in the Irish Affected Sib Pair Study of alcohol dependence (IASPSAD) sample.

ADH1A ADH1B ADH1C

4.16e-068148318331377
Pubmed

Biochemical and genetic characterization of esterase-27 (ES-27), the major plasma cholinesterase of the house mouse (Mus musculus).

ADH1A ADH1B ADH1C

4.16e-06814832040456
Pubmed

[Genetic analysis of interspecific crosses Mus musculus L. x Mus spretus Lataste: linkage of Adh-1 with Amy-1 on chromosome 3 and Es-14 with Mod-1 on chromosome 9].

ADH1A ADH1B ADH1C

6.23e-069148393520
Pubmed

Quantitative axial profiles of retinoic acid in the embryonic mouse spinal cord: 9-cis retinoic acid only detected after all-trans-retinoic acid levels are super-elevated experimentally.

ADH1A ADH1B ADH1C

6.23e-069148311747070
Pubmed

Defining the human deubiquitinating enzyme interaction landscape.

CUL2 MYO1C KBTBD6 ADRM1 NPEPPS FTSJ1 ICE1 USP8 USP5 LRPPRC UBE2O DDX23 POLR1B VSIG8 ARIH1 PLK1

6.52e-0610051481619615732
Pubmed

PINK1 Content in Mitochondria is Regulated by ER-Associated Degradation.

MYO1C ADRM1 NPEPPS SPTBN1 LRPPRC UBE2O SMPDL3B CDC40 LMO7 MTHFD1 ZNF804B

6.82e-064771481131300519
Pubmed

Altered expression of genes involved in regulation of vitamin A metabolism, solute transportation, and cytoskeletal function in the androgen-insensitive tfm mouse testis.

ADH1A ADH1B ADH1C SBDS

1.03e-0532148417332066
Pubmed

Ontogeny of rdh9 (Crad3) expression: ablation causes changes in retinoid and steroid metabolizing enzymes, but RXR and androgen signaling seem normal.

RARB ADH1A ADH1B ADH1C

1.03e-0532148417270348
Pubmed

KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.

MYO1C CORO2A NPEPPS SPTB SPTBN1 KANK2 USP5 LRPPRC UBE2O CORO2B LMO7 MTHFD1 KCNQ2 C1QB PLCL1 RPS10P5 ATP2B1 KNG1 PRPS1

1.14e-0514311481937142655
Pubmed

The murine M-CSF gene is localized on chromosome 3.

ADH1A ADH1B ADH1C

1.22e-051114832565740
Pubmed

Local anesthetics impair the growth and self-renewal of glioblastoma stem cells by inhibiting ZDHHC15-mediated GP130 palmitoylation.

ZNF112 UBE2O ATRNL1 CRYBG3 MUC5AC

1.35e-0571148533541421
Pubmed

Paralog knockout profiling identifies DUSP4 and DUSP6 as a digenic dependence in MAPK pathway-driven cancers.

PRPS2 CUL2 CORO2A ADAMTS8 LRP1B ADAMTS12 MTHFD1 PLCL1 ARIH1 PLK1 ATP2B1 PLK3 PRPS1

1.57e-057301481334857952
Pubmed

Expression of genes for alcohol and aldehyde metabolizing enzymes in mouse oocytes and preimplantation embryos.

ADH1A ADH1B ADH1C

1.62e-0512148312128098
Pubmed

Differential gene expression in the developing mouse ureter.

ADH1A ADH1B ADH1C

1.62e-0512148316459152
Pubmed

Structures of three human beta alcohol dehydrogenase variants. Correlations with their functional differences.

ADH1B ADH1C

1.80e-05214828201622
Pubmed

Immunoglobulin E sensitization to cross-reactive carbohydrate determinants: epidemiological study of clinical relevance and role of alcohol consumption.

ADH1B ADH1C

1.80e-052148220357489
Pubmed

Alcohol dehydrogenase 3 genotype is not associated with risk of squamous cell carcinoma of the oral cavity and pharynx.

ADH1A ADH1C

1.80e-052148211303599
Pubmed

Plk1 phosphorylation of CAP-H2 triggers chromosome condensation by condensin II at the early phase of mitosis.

NCAPH2 PLK1

1.80e-052148228717250
Pubmed

Genetic associations of alcohol dehydrogenase with alcohol use disorders and endophenotypes in white college students.

ADH1B ADH1C

1.80e-052148216117582
Pubmed

Alcohol-metabolizing genes and alcohol phenotypes in an Israeli household sample.

ADH1B ADH1C

1.80e-052148223895337
Pubmed

Association of the ADH2*3 allele with greater alcohol expectancies in African-American young adults.

ADH1B ADH1C

1.80e-052148212713190
Pubmed

PDZ motifs in PTP-BL and RIL bind to internal protein segments in the LIM domain protein RIL.

PDLIM4 PTPN13

1.80e-05214829487134
Pubmed

Alcohol consumption and risk of atrial fibrillation: Observational and genetic estimates of association.

ADH1B ADH1C

1.80e-052148227071860
Pubmed

Structure, dynamics and binding characteristics of the second PDZ domain of PTP-BL.

PDLIM4 PTPN13

1.80e-052148211884147
Pubmed

Alcohol intake, ADH1B and ADH1C genotypes, and the risk of colorectal cancer by sex and subsite in the Netherlands Cohort Study.

ADH1B ADH1C

1.80e-052148229390059
Pubmed

Genetic variants in or near ADH1B and ADH1C affect susceptibility to alcohol dependence in a British and Irish population.

ADH1B ADH1C

1.80e-052148224735490
Cytoband4q23

ADH1A ADH1B ADH1C

3.52e-052014734q23
CytobandEnsembl 112 genes in cytogenetic band chr4q23

ADH1A ADH1B ADH1C

2.31e-04371473chr4q23
Cytoband9q22.3

CORO2A FBP1

6.58e-041214729q22.3
Cytoband22q12.2

SEC14L3 SEC14L6 SEC14L4

8.72e-0458147322q12.2
CytobandEnsembl 112 genes in cytogenetic band chr17p13

DPH1 MYH3 MYO1C HASPIN ALOXE3 SMG6

9.11e-043461476chr17p13
Cytoband17p13.3

DPH1 MYO1C SMG6

2.89e-0388147317p13.3
Cytoband11q25

ADAMTS8 IGSF9B

3.15e-0326147211q25
Cytoband3q11.2

EPHA6 CRYBG3

3.15e-032614723q11.2
GeneFamilySEC14 family|PRELI domain containing

SEC14L3 SEC14L6 SEC14L4

3.44e-06610231063
GeneFamilyAlcohol dehydrogenases

ADH1A ADH1B ADH1C

9.56e-0681023397
GeneFamilyFibronectin type III domain containing

NPHS1 EPHA6 ROS1 IGSF9B CDON SORL1

2.92e-041601026555
GeneFamilyWD repeat domain containing|Coronins

CORO2A CORO2B

6.50e-0471022495
GeneFamilyEF-hand domain containing|Spectrins

SPTB SPTBN1

6.50e-04710221113
GeneFamilySUMO specific peptidases

SENP6 SENP7

6.50e-0471022984
GeneFamilyG protein-coupled receptors, Class C orphans

GPRC5A GPR179

6.50e-0471022285
GeneFamilyZinc fingers C2H2-type|ZF class homeoboxes and pseudogenes

ZNF354A ZNF628 ZNF227 ZNF112 PRDM1 ZSCAN29 ZNF792 ZNF41 ZNF425 ZNF69 ZNF76 PRDM15

7.19e-047181021228
GeneFamilyMyosins, class I

MYO1G MYO1C

8.63e-04810221097
GeneFamilyEndogenous ligands|Minor histocompatibility antigens

MYO1G DPH1 MTHFD1

2.98e-03511023870
GeneFamilyZinc fingers C2H2-type|PR/SET domain family

PRDM1 PRDM15

4.06e-031710221197
GeneFamilyADAM metallopeptidases with thrombospondin type 1 motif

ADAMTS8 ADAMTS12

5.06e-0319102250
GeneFamilyProteases, serine

PRSS3 KLK6 TMPRSS11E

5.42e-03631023738
GeneFamilyPleckstrin homology domain containing|Rho guanine nucleotide exchange factors|C2 domain containing

SPTB SPTBN1 ASAP2 OSBPL5 PLEKHA1

6.24e-032061025682
ToppCelldroplet-Heart-4Chambers-21m-Hematologic-coronary_vascular_endothelial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYO1G LHPP UBE2O SMPDL3B IGSF9B SENP7 SMG6

1.58e-061711467e852d0e8589eecf4a2e5fea039b52a67c5d58dbd
ToppCellPSB-critical-LOC-Epithelial-Squamous|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

PRSS3 KLK6 TMPRSS11E GPRC5A PRDM1 LMO7 PAX6

2.47e-0618314672cf798a2371c61322484ea16fdfae0acfa94f102
ToppCellPCW_10-12-Epithelial-Epithelial_neuroendo-epi_NE_progenitor_(7)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

EPHA6 TFF3 FZD6 FBP1 LMO7 ZNF804B MUC5AC

2.96e-0618814673cfba3addcc9058f4ec31ad96261f79988f551a0
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

RARB ITGA1 SVEP1 ADH1B ADAMTS12 ATRNL1 CRYBG3

3.06e-061891467c734e5693808a0333139e87bd5be2597a9252afe
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

RARB ITGA1 SVEP1 ADH1B ADAMTS12 XYLT1 ATRNL1

3.17e-0619014672306aa9dbeaef3be8484a5b236605de23cd75d4c
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

RARB ITGA1 SVEP1 ADH1B ADAMTS12 ATRNL1 CRYBG3

3.17e-0619014672e592323085ba9c019d678ac2a784462ab470ed9
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

RARB ITGA1 SVEP1 ADH1B ADAMTS12 XYLT1 ATRNL1

3.17e-0619014671f83f7f24288a3b9ab33c2e113e845dba96adc8a
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

RARB ITGA1 SVEP1 ADH1B ADAMTS12 ATRNL1 CRYBG3

3.17e-061901467445952b70abffadb6ccc1ed4bbf61a88b06b73b3
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

RARB ITGA1 SVEP1 ADH1B ADAMTS12 XYLT1 ATRNL1

3.28e-061911467a58c75e9580139fb370b498d95660f10f3a2a27b
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Mesenchymal|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

RARB ITGA1 SVEP1 ADH1B ADAMTS12 ATRNL1 CRYBG3

3.28e-061911467806b94f567ea09a9f443cd4091e70cdb1253ac08
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

RARB ITGA1 SVEP1 ADH1B ADAMTS12 XYLT1 ATRNL1

3.40e-0619214679093a9e94a25682d109a7f6edc256a25a61103a0
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

RARB ITGA1 SVEP1 ADH1B ADAMTS12 XYLT1 ATRNL1

3.40e-0619214679ed5d49621ec1aa01716dc369bba1450b5f015f5
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

RARB ITGA1 SVEP1 ADH1B ADAMTS12 XYLT1 ATRNL1

3.51e-061931467c8c21eee8c6c086dc2faf416669cd4a002870fbe
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

RARB ITGA1 SVEP1 ADH1B ADAMTS12 XYLT1 ATRNL1

3.51e-0619314675b602b1702283184bd3943c2a6f2290b7c37e407
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

RARB ITGA1 SVEP1 ADH1B ADAMTS12 XYLT1 ATRNL1

3.76e-061951467d9a5c75d31c6e8bb1e1ab7fd115ac5deb5fb1c8d
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

RARB ITGA1 SVEP1 ADH1B ADAMTS12 XYLT1 ATRNL1

3.76e-061951467cad6563cc51d212554152c727fc2c249c6a07e4d
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ITGA1 KANK2 SVEP1 ADH1B ADAMTS12 XYLT1 ATRNL1

3.76e-061951467edd4cd8402af81737b2074f9dce71cc6ab09be7e
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PI16 ITGA1 SVEP1 ADH1B ADAMTS12 ATRNL1 CDON

3.76e-0619514673c3703f092b6fc1b7333426fb5e2823bfb74bb57
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

RARB ITGA1 SVEP1 ADH1B ADAMTS12 XYLT1 ATRNL1

3.76e-061951467783bfa8110161cbd6def50ce849cae676c39c458
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

RARB ITGA1 SVEP1 ADH1B ADAMTS12 XYLT1 ATRNL1

3.89e-061961467a12dd986df65c36f248cf10815c3b8b6238613b0
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

RARB ITGA1 SVEP1 ADH1B ADAMTS12 XYLT1 ATRNL1

3.89e-0619614673e6803587d8566fd08cb8b290be3b6461743d79c
ToppCellcritical-Epithelial-Squamous|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

PRSS3 KLK6 TMPRSS11E GPRC5A PRDM1 ABHD5 LMO7

4.02e-061971467cfbdaada7169afb68455724ae87032ff311b2d89
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

RARB ITGA1 SVEP1 ADH1B ADAMTS12 XYLT1 ATRNL1

4.02e-06197146709946ee8dfb15a2a32da06e5b331f3277ee934f4
ToppCellNS-control-d_0-4-Epithelial-Squamous|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

PRSS3 KLK6 TMPRSS11E GPRC5A PRDM1 ABHD5 LMO7

4.02e-061971467ab965a0ba87efd3329d24a1ec123985f46fc17c0
ToppCellmoderate-Epithelial-Squamous|moderate / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

PRSS3 KLK6 TMPRSS11E GPRC5A PRDM1 ABHD5 LMO7

4.02e-061971467ab3c90a5b643b45d0b83939c6304b11f567c5d78
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

RARB ITGA1 SVEP1 ADH1B ADAMTS12 XYLT1 ATRNL1

4.02e-0619714676d027119a5f7ca2aac1b10837e43f9a2bb54db85
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

RARB ITGA1 SVEP1 ADH1B ADAMTS12 XYLT1 ATRNL1

4.02e-061971467b349f8e96d61a4c296af64711e11fc44459a9413
ToppCellmoderate-Epithelial-Squamous|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

PRSS3 KLK6 TMPRSS11E GPRC5A PRDM1 ABHD5 LMO7

4.02e-0619714672e13881f917d4f62a5b3e968e41c57e43300d988
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

RARB ITGA1 SVEP1 ADH1B ADAMTS12 XYLT1 ATRNL1

4.02e-061971467c2e390653d5dee7e731c1840cfdab41987dede9b
ToppCellcontrol-Epithelial-Squamous|control / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

PRSS3 KLK6 TMPRSS11E GPRC5A PRDM1 ABHD5 LMO7

4.16e-0619814676ba669ac1ed275ae309054941b1457e315766faa
ToppCellNS-moderate-d_07-13-Epithelial-Squamous|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

PRSS3 KLK6 TMPRSS11E GPRC5A PRDM1 ABHD5 LMO7

4.16e-061981467b7495369baba203490c067a58fc8456a778a12e4
ToppCellcontrol-Epithelial-Squamous|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

PRSS3 KLK6 TMPRSS11E GPRC5A PRDM1 ABHD5 LMO7

4.30e-061991467e13dca7a055cdca53dd6c26c04b2a46d58b419b6
ToppCellTracheal-NucSeq-Stromal-Peri/Epineurial_|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

SPTBN1 KANK2 SVEP1 ADH1B ADH1C ADAMTS12 PTPN13

4.30e-0619914673835452e4848d7f7dd8651c17b746b271ef39688
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Degenerative_Fibroblast-Degenerative_Fibroblast_26.46.91|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

RARB SVEP1 ADH1A KIAA1210 ATRNL1 PAX6

4.31e-0612914666abdba987c8528f7cb90b32dc01796e02c7352c9
ToppCellControl_saline-Mesenchymal_fibroblastic-Fibroblasts-MatrixFB|Control_saline / Treatment groups by lineage, cell group, cell type

CASS4 ADAMTS8 KANK2 SVEP1 ADAMTS12 PXDNL ATP2B1

4.44e-062001467bd8cf33502adea320e91ca2af14e1911d88ad374
ToppCellTCGA-Thryoid-Solid_Tissue_Normal-Thryoid_normal_tissue-Thryoid_normal_tissue-3|TCGA-Thryoid / Sample_Type by Project: Shred V9

EPHA6 LRP1B ADH1B ADH1C ZNF804B IGSF9B

1.19e-0515414664e9203c220a44c70cd7979796a0b461991422257
ToppCellTCGA-Thryoid-Solid_Tissue_Normal-Thryoid_normal_tissue-Thryoid_normal_tissue|TCGA-Thryoid / Sample_Type by Project: Shred V9

EPHA6 LRP1B TFF3 ADH1B ADH1C ZNF804B

1.38e-0515814668e48952af0831a1fc71ad422e8216b5a92a75991
ToppCellTCGA-Thryoid-Solid_Tissue_Normal-Thryoid_normal_tissue|TCGA-Thryoid / Sample_Type by Project: Shred V9

EPHA6 LRP1B TFF3 ADH1B ADH1C ZNF804B

1.38e-051581466e5b55c15a8c99c8d7fc94949f0d3c22e0c3fee7b
ToppCellTCGA-Thryoid-Solid_Tissue_Normal|TCGA-Thryoid / Sample_Type by Project: Shred V9

EPHA6 LRP1B TFF3 ADH1B ADH1C ZNF804B

1.38e-05158146655214d674808584e4d48f8c5e3b8c0e206cb9bb8
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

RARB GPRC5A PTPN13 LMO7 ZNF69 PLCL1

2.09e-051701466a2c738e441ced90eeeb1fcc6ca3269b918aaa298
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Cycling_Myofibroblast-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

DPF1 ITGA1 ADH1A ADAMTS12 XYLT1 ATRNL1

2.16e-051711466b0373ed8283ee1792b6a490bff93906546978593
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Cycling_Myofibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

DPF1 ITGA1 ADH1A ADAMTS12 XYLT1 ATRNL1

2.16e-051711466b92963f9f247d2e5e2e6c51c6dbf70e527cd2f55
ToppCelldroplet-Thymus-nan-21m-Lymphocytic-B_cell|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PRAG1 GPR179 ZSCAN29 DDX23 PLEKHA1 CRYBG3

2.30e-0517314660a0cd40bb5f61431fe34758626c8a63ec610a8a5
ToppCell343B-Fibroblasts-Fibroblast-A_(Fibroblast_progenitors)-|343B / Donor, Lineage, Cell class and subclass (all cells)

PI16 KANK2 LRP1B SVEP1 ADH1A ADH1B

2.54e-0517614662e94bbe17c0bb65dc58b4ebc0cb829258bd7373b
ToppCell343B-Fibroblasts-Fibroblast-A_(Fibroblast_progenitors)|343B / Donor, Lineage, Cell class and subclass (all cells)

PI16 KANK2 LRP1B SVEP1 ADH1A ADH1B

2.54e-051761466f33ab41d121b59d871ad7d48ca021524a027d2ef
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-proliferative_fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ITGA1 SVEP1 ADH1B ADAMTS12 XYLT1 ATRNL1

2.62e-051771466b872ee91e01265b101b81bd304cf6b95d5419e68
ToppCellBAL-Severe-Epithelial-Epithelial-undefined_Epi-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

GPRC5A TFF3 PDLIM4 GJB3 LMO7 MUC5AC

2.70e-0517814669a3ef66814dfca7b37024e7f79e86ea8c72ae10f
ToppCell356C-Fibroblasts-Fibroblast-E-|356C / Donor, Lineage, Cell class and subclass (all cells)

SNHG28 PI16 SVEP1 ADH1B CORO2B CDON

2.70e-051781466a493a277d175e5e153410a745b26ebe2e0839ea0
ToppCellBAL-Severe-Epithelial-Epithelial-undefined_Epi-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

GPRC5A TFF3 PDLIM4 GJB3 LMO7 MUC5AC

2.70e-051781466b413a634283550fa224db7d0d05956e3f64694a1
ToppCellBAL-Severe-Epithelial-Epithelial-undefined_Epi|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

GPRC5A TFF3 PDLIM4 GJB3 LMO7 MUC5AC

2.70e-05178146649a2271718637522f74334068d252963ee13b1ce
ToppCell356C-Fibroblasts-Fibroblast-E|356C / Donor, Lineage, Cell class and subclass (all cells)

SNHG28 PI16 SVEP1 ADH1B CORO2B CDON

2.70e-051781466371218babddfd3d8a7bb82a46ce65327ee3fcf12
ToppCellBAL-Severe-Epithelial-Epithelial-undefined_Epi|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

GPRC5A TFF3 PDLIM4 GJB3 LMO7 MUC5AC

2.70e-05178146619b5432aa1d7f616d58a106543c18cf2d7ca840c
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-kidney_interstitial_fibroblast_5|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

RARB ITGA1 SVEP1 ADAMTS12 XYLT1 ATRNL1

2.70e-051781466d4ecb84e9b1f4ec49c519321156aa10f9bd34cce
ToppCellClub_cells-SSc-ILD_01|World / lung cells shred on cell class, cell subclass, sample id

GPRC5A NUTM2G TFF3 PDLIM4 GJB3 MUC5AC

2.70e-051781466be64d4be23fb96a4cdd7980c58880fdfe817747f
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_3-Exc_L3_RORB_CARTPT|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PRSS3 EPHA6 PRAG1 PTPN13 ROS1 CRYBG3

2.88e-0518014665e78b29fa1cbdcf502fee3577e5b45766b90d1dc
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

RARB ITGA1 SVEP1 ADH1B ADAMTS12 ATRNL1

2.88e-051801466280ff5c8f292be1b88120db5ff1788b750644856
ToppCell368C-Lymphocytic-ILC-ILC-2|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

KBTBD6 CORO2A ITGA1 XYLT1 MLH3 CDON

2.88e-051801466eb5a57604c7f2ad256c300085dbf5069d0ae1ad0
ToppCell368C-Lymphocytic-ILC|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

KBTBD6 CORO2A ITGA1 XYLT1 MLH3 CDON

2.88e-051801466ddba4dc3bbcfe4e4a22400be73bbc62d3ff27d3c
ToppCell390C-Fibroblasts-Fibroblast-G|390C / Donor, Lineage, Cell class and subclass (all cells)

CASS4 ADAMTS8 KANK2 SVEP1 ADH1B ADAMTS12

2.88e-051801466137fc14859c89e1ecd98bee388bb58c04b835847
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

RARB ITGA1 SVEP1 ADH1B ADAMTS12 ATRNL1

2.88e-051801466fdbd7c22044d9328a1e06e2f9a4451529d1df767
ToppCell5'-GW_trimst-2-SmallIntestine-Epithelial-neuro-epithelial-EC_cells_(TAC1+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

AMER3 LRP1B TFF3 ADH1A ROS1 PAX6

2.88e-0518014666b1606238417490e0d9930870a7827419d1c3737
ToppCell390C-Fibroblasts-Fibroblast-G-|390C / Donor, Lineage, Cell class and subclass (all cells)

CASS4 ADAMTS8 KANK2 SVEP1 ADH1B ADAMTS12

2.88e-051801466cd6790de050151fedfa2c5ea6ad58b72665414b2
ToppCellB_cell_maturation-immature_B_cell|World / Lineage and Cell class

RNGTT MYO1C SPTBN1 LHPP KANK2 CDC40

3.06e-0518214662c7c51ebc4125d8a33454ffee0b143579ce5e451
ToppCellFrontal_cortex-Neuronal-Excitatory-eN1(Slc17a7)-eN1_2-Parm1|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

EPHA6 XYLT1 ATP2B1 SEC14L4 SORL1

3.27e-0511114651847dde68d349114286bc3317be6339666df4aa2
ToppCellPCW_05-06-Mesenchymal-Mesenchymal_fibroblastic-mes_immature_adventitial_fibro_(9)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

LRP1B SORCS1 CNTNAP5 ZNF804B FOXG1 CDON

3.46e-0518614668915436d09775f2828a7678af203b1082b36e21c
ToppCellB_cell_maturation-immature_B_cell|B_cell_maturation / Lineage and Cell class

RNGTT MYO1C SPTBN1 LHPP KANK2 CDC40

3.56e-0518714669afbb21654c8eb6f9c6a7cbd0664d890282ddceb
ToppCellCF-Lymphoid-T_cell_&_NK_cell|Lymphoid / Disease state, Lineage and Cell class

CASS4 AOAH ITGA1 PRDM1 PTPN13 DTHD1

3.67e-05188146615057036b46c9df621ec4955aa94ca3036245d45
ToppCellSevere_COVID-19-Epithelial-undefined_Epi|Severe_COVID-19 / Disease group,lineage and cell class (2021.01.30)

GPRC5A TFF3 PDLIM4 GJB3 LMO7 MUC5AC

3.78e-0518914668cbd35320c7e7ff013ef0c0f13f8d875db1c53cd
ToppCell3'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.0.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PRSS3 ADH1C PTPN13 LMO7 MUC5AC FOXG1

3.89e-0519014666ea9fa08bd97bedcb21d3654467e7f8dd74c8fd0
ToppCellPCW_07-8.5-Epithelial-Epithelial_alveolar-distal-epi_SOX9^high_Etv5^high_distal_(10)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

CORO2A FZD6 CFAP54 SMPDL3B LMO7 SORL1

3.89e-051901466625c08a0e5227efc46daa512fd579c3938ff76c7
ToppCell(5)_Fibroblasts-(5)_Fibroblast-C_(Myofibroblast)|(5)_Fibroblasts / Lung cell shreds - cell class (v4) and cell subclass (v4)

CASS4 RARB SPTBN1 ADH1B ADAMTS12 SORL1

3.89e-05190146671e112dfb8c3190fe0286b45a046ea789eb6a8db
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ITGA1 SVEP1 ADH1B ADAMTS12 XYLT1 ATRNL1

4.01e-051911466a6c57627077fa980b7ec1d3894b5f31bfb11b738
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

RARB ITGA1 SVEP1 ADH1B ATRNL1 CRYBG3

4.01e-051911466c54c420a94dc749ebc67fc64c5614663f4b9798d
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

RARB ITGA1 SVEP1 ADH1B ADAMTS12 ATRNL1

4.01e-0519114661caf726bd07fdca389e678fc16304a6ef1790423
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

RARB ITGA1 SVEP1 ADH1B ATRNL1 CRYBG3

4.01e-051911466cb0aee740b08f7d5fdd2717ecf7429043b277ae7
ToppCellAdult-Immune-natural_killer_cell|Adult / Lineage, Cell type, age group and donor

AOAH APOBEC3G PRDM1 OSBPL5 DTHD1 SORL1

4.01e-051911466758ec27e47d7662a5175305e98a1506c6859dbf7
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ITGA1 KANK2 SVEP1 ADAMTS12 XYLT1 ATRNL1

4.01e-051911466107113b930d9ad171f1b2aa20df4567c94fae7d8
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ITGA1 KANK2 SVEP1 ADAMTS12 XYLT1 ATRNL1

4.01e-051911466bc353a79a1d11ca52bba5e3874a80d432e1a7715
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ITGA1 SVEP1 ADH1B ADAMTS12 XYLT1 ATRNL1

4.01e-0519114668f6d592edc32fdb901af30501d4360512334e8c2
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

RARB ITGA1 SVEP1 ADH1B ADAMTS12 ATRNL1

4.01e-0519114663d60c46bced2984c27a1fcf2910bc38b31fb0148
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Mesenchymal|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

RARB ITGA1 SVEP1 ADH1B ADAMTS12 ATRNL1

4.13e-0519214664022f208eb5db760abd0aac782a25e8ab63efc64
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ITGA1 SVEP1 ADH1B ADAMTS12 XYLT1 ATRNL1

4.13e-051921466bc84b9ce01b4d826a682842ab8a395dac9b91183
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ITGA1 SVEP1 ADH1B ADAMTS12 ATRNL1 CDON

4.13e-0519214665105e4b577408b4e1a62d0a44c23c2b830ccad88
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

RARB ITGA1 SVEP1 ADH1B ADAMTS12 ATRNL1

4.13e-0519214669333aba0d04203ccccad78d82bf6359922f810a7
ToppCellNS-moderate-d_16-33-Epithelial-Squamous|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

PRSS3 KLK6 TMPRSS11E GPRC5A PRDM1 LMO7

4.13e-051921466103496f428f59683ac3ae6147682c07c30663724
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ITGA1 SVEP1 ADH1B ADAMTS12 XYLT1 ATRNL1

4.13e-0519214660ab1176cfbb0de8dd1f22c6e2c41265cf6c10ee1
ToppCellCOPD-Stromal-Myofibroblast|Stromal / Disease state, Lineage and Cell class

CASS4 RARB ADAMTS8 ITGA1 SVEP1 ADAMTS12

4.13e-05192146662904f94dfce430456f05066522cbf9bd29f4d7e
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ITGA1 SVEP1 ADH1B ADAMTS12 XYLT1 ATRNL1

4.25e-051931466f1199518c3626fd29bfce65070dd21a660671213
ToppCellMesenchymal-matrix_fibroblast_1_cell|World / Lineage, Cell type, age group and donor

CASS4 ADAMTS8 ITGA1 SVEP1 ADH1B ADAMTS12

4.25e-051931466acad568621ed677031797b8c2e34dafea798d681
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ITGA1 SVEP1 ADH1B ADAMTS12 XYLT1 ATRNL1

4.37e-05194146681713e0409e8be695ba5dfdc67a997b33435dd9e
ToppCellFetal_29-31_weeks-Mesenchymal-matrix_fibroblast_1_cell|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

CASS4 ADAMTS8 ITGA1 SVEP1 ADH1B ADAMTS12

4.37e-051941466011e14d9ed1393275f892060e7708ffadcd0767f
ToppCell3'-GW_trimst-2-LargeIntestine-Epithelial|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PRSS3 GPRC5A TFF3 GJB3 LMO7 SORL1

4.37e-05194146607d8e38cbc2c7f0564c14f7c365f345f901b73b2
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ITGA1 SVEP1 ADH1B ADAMTS12 XYLT1 ATRNL1

4.37e-051941466cf0244a29934e515446ac917d3c30672b460fb04
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

RARB ITGA1 SVEP1 ADH1B ADAMTS12 ATRNL1

4.37e-051941466240d122dcb9dd1ab2867503ad85869853adcacae
ToppCellNS-critical-d_07-13-Epithelial-Squamous|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

PRSS3 KLK6 TMPRSS11E GPRC5A PRDM1 LMO7

4.37e-05194146653a34843d529ef395deb27086f71f7049a087bab
ToppCellNS-critical-d_0-4-Epithelial-Squamous|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

PRSS3 KLK6 TMPRSS11E GPRC5A PTPN13 LMO7

4.37e-051941466614d0c25b56957c70f397abb169fd2a860eb1c06
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

RARB ITGA1 SVEP1 ADH1B ADAMTS12 ATRNL1

4.37e-051941466ae7df037592f1c20c9d32be15fe6fc3c562ebeb1
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

RARB ITGA1 SVEP1 ADH1B ADAMTS12 ATRNL1

4.37e-05194146690efdbd7f1c85fd7fd622b10340250b1d8fc1197
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ITGA1 SVEP1 ADH1B ADAMTS12 XYLT1 ATRNL1

4.37e-051941466e03ba6caed59fa64d4d9b042593469d4a6a3dc10
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

RARB ITGA1 SVEP1 ADH1B ADAMTS12 ATRNL1

4.37e-051941466df82cce5ebeb73740b02cf816c6df82253cfd566
Drug4-Iodopyrazole

ADH1A ADH1B ADH1C

2.43e-0731433DB02721
DrugFomepizole

ADH1A ADH1B ADH1C

9.66e-0741433DB01213
DrugAC1L1AO2

PRPS2 PRPS1L1 FBP1 PRPS1

4.26e-06181434CID000001073
Drugmethyl iodoacetate

PRPS2 PRPS1L1 PRPS1

4.79e-0661433CID006429536
DrugAPP-MP

PRPS2 PRPS1L1 PRPS1

4.79e-0661433CID003081102
Drugpyrimidine-5-nucleotide

PRPS2 PRPS1L1 PRPS1

4.79e-0661433CID000440040
Drugfructose 3-phosphate

PRPS2 PRPS1L1 ARIH1 PRPS1

6.68e-06201434CID000130872
DrugEthanol

ADH1A ADH1B ADH1C

8.34e-0671433DB00898
DrugN-heptylformamide

ADH1A ADH1B ADH1C

1.33e-0581433CID000347402
Drug2-NA

ADH1A ADH1B ADH1C

1.98e-0591433CID000074128
Drug(3R,7R)-17-(6-hydroxy-1,5-dimethyl-hexyl)-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthrene-3,7-diol

ADH1A ADH1B ADH1C

1.98e-0591433CID000440672
DrugHFCO

MTHFD1 PLK1 PLK3

2.82e-05101433CID000015153
Drug2,8-dihydroxyadenine

PRPS2 PRPS1L1 GLB1 PRPS1

3.14e-05291434CID000092268
DrugSeneciphylline [480-81-9]; Down 200; 12uM; MCF7; HT_HG-U133A

CUL2 RANBP3 FZD6 ORC5 PTPN13 OSGEPL1 SENP6 ATP2B1

3.20e-0519414384822_DN
DrugPramoxine hydrochloride [637-58-1]; Down 200; 12.2uM; MCF7; HT_HG-U133A

STAB2 SPTBN1 NCAPH2 ZFYVE9 WNT16 ZNF76 TNKS2 SMG6

3.57e-0519714383894_DN
DrugMoxisylyte hydrochoride [964-52-3]; Up 200; 12.6uM; MCF7; HT_HG-U133A

RNGTT RANBP3 NCAPH2 ZFYVE9 OSGEPL1 KCTD20 FOXG1 SMG6

3.57e-0519714381682_UP
DrugTolbutamide [64-77-7]; Up 200; 14.8uM; MCF7; HT_HG-U133A

CUL2 PRSS3 SPTBN1 NCAPH2 SVEP1 ADAMTS12 ZFYVE9 ZNF76

3.98e-0520014383886_UP
Drug2,5-anhydro-D-mannitol

PRPS2 PRPS1L1 FBP1 PRPS1

4.11e-05311434CID000001494
DrugAC1L1J0I

ADH1A ADH1B ADH1C

5.12e-05121433CID000030201
DrugDhga

PRPS2 PRPS1L1 PRPS1

5.12e-05121433CID000467478
Drughexa-2,4-dien-1-ol

ADH1A ADH1B ADH1C

5.12e-05121433CID000008104
DrugLeupeptin hydrochloride

PRSS3 KLK6 SPTB SPTBN1 PPP1R3A ZFYVE9 GLB1 SENP6 KNG1

6.42e-052761439CID000003910
Drug2,6,6-tetramethylpiperidine

PRPS2 PRPS1L1 PRPS1

6.63e-05131433CID000013035
Drug2-naphthaldehyde

ADH1A ADH1B ADH1C

6.63e-05131433CID000006201
Drug2,6-diaminonebularine

PRPS2 PRPS1L1 PRPS1

6.63e-05131433CID000072200
Drug3-methylbutanal

ADH1A ADH1B ADH1C

6.63e-05131433CID000011552
DrugS)-HPMPA

PRPS2 PRPS1L1 SMG6 PRPS1

7.52e-05361434CID000072253
DrugHPMPApp

PRPS2 PRPS1L1 PRPS1

8.39e-05141433CID000506018
Drugnaphthalenemethanol

ADH1A ADH1B ADH1C

8.39e-05141433CID000020908
Diseasebitter alcoholic beverage consumption measurement

ADH1B ADH1C ORC5 LRPPRC IGSF9B SENP7 SORL1

3.20e-061331387EFO_0010092
Diseaselower face morphology measurement

PRAG1 LRP1B CORO2B OSBPL5 PLCL1 SMG6

1.28e-051091386EFO_0010948
Diseasealcohol use disorder measurement, longitudinal alcohol consumption measurement

ADH1A ADH1B ADH1C LRPPRC

2.68e-05371384EFO_0007645, EFO_0009458
DiseaseAstigmatism

CASS4 MYO1G XYLT1 SMPDL3B LMO7 PLCL1

3.33e-051291386HP_0000483
Diseaseopen-angle glaucoma

RARB NPEPPS LHPP ADAMTS8 SVEP1 LMO7 SMG6

3.38e-051911387EFO_0004190
Diseaselung adenocarcinoma (is_implicated_in)

RARB LRP1B PRDM1 PTPN13

8.24e-05491384DOID:3910 (is_implicated_in)
Diseasealcohol use disorder measurement, alcohol consumption measurement

ADH1B ADH1C ORC5 LRPPRC SORL1

9.49e-05971385EFO_0007878, EFO_0009458
Diseasespinocerebellar ataxia type 5 (implicated_via_orthology)

SPTB SPTBN1

1.29e-0441382DOID:0050882 (implicated_via_orthology)
Diseaseautosomal recessive congenital ichthyosis 1 (is_implicated_in)

ABHD5 ALOXE3

1.29e-0441382DOID:0060656 (is_implicated_in)
Diseasefactor XI measurement, coronary artery disease

AOAH SEC14L3 ATP2B1 KNG1 SMG6

2.11e-041151385EFO_0001645, EFO_0004694
DiseaseAlcohol dependence

ADH1B ADH1C

2.15e-0451382cv:C0001973
DiseaseALCOHOL DEPENDENCE

ADH1B ADH1C

2.15e-0451382103780
DiseaseIGF-1 measurement

STAB2 EPHA6 TMPRSS11E ADAMTS8 ADH1A ADH1B ADH1C LRPPRC SENP7

5.02e-044881389EFO_0004627
Diseaseosteoarthritis

PRAG1 USP8 ASAP2 ATRNL1 SENP6 SMG6

6.38e-042221386MONDO_0005178
Diseaseresponse to 4'-epidoxorubicin, response to antineoplastic agent

LHPP ICE1

7.65e-0491382GO_0097327, GO_1902522
Diseaseunipolar depression, bipolar disorder

MYO1G C1orf53 PXDNL MMRN2 PLCL1

8.53e-041561385EFO_0003761, MONDO_0004985
Diseaseprotein intake measurement

RARB ADH1B

9.53e-04101382EFO_0010810
Diseasesubiculum volume

SPTBN1 LHPP PLCL1

1.08e-03431383EFO_0009399
Diseasemyeloid white cell count

MYO1G MYO1C PIEZO1 SPTBN1 USP8 UBE2O POLR1B TNKS2 DTHD1 TM2D1 SMG6 SORL1

1.54e-0393713812EFO_0007988
DiseaseC-reactive protein measurement

LRRC3C RARB ITGA1 ZNF227 ZNF112 PRAG1 KANK2 NT5DC1 ADH1B ADH1C FBP1 DNAJC5 POLR1B VSIG8

1.60e-03120613814EFO_0004458
Diseasevelocity of sound measurement

SPTBN1 WNT16

1.64e-03131382EFO_0005654
Diseaseovary epithelial cancer (is_marker_for)

PLK1 PLK3

1.64e-03131382DOID:2152 (is_marker_for)
Diseaserevision of total hip arthroplasty

ICE1 ADAMTS12

1.90e-03141382EFO_0020973
Diseasefactor VIII measurement, coronary artery disease

STAB2 SEC14L3 ATP2B1 SMG6

1.99e-031131384EFO_0001645, EFO_0004630
DiseaseProteinuria

RARB SMG6

2.19e-03151382HP_0000093
Diseasealcohol dependence measurement

ADH1A ADH1B ADH1C

2.20e-03551383EFO_0007835
Diseaseisoleucine measurement

ADH1A ADH1B ZNF804B

2.31e-03561383EFO_0009793
Diseaseabdominal fat cell number

SNHG28 RARB RNGTT SPTBN1 VSIG8

2.44e-031981385EFO_0021534
Diseasesugar consumption measurement

RARB SORCS1 LRPPRC IGSF9B

2.47e-031201384EFO_0010158
Diseasealcohol use disorder (is_implicated_in)

ADH1B ADH1C

2.50e-03161382DOID:1574 (is_implicated_in)
DiseaseSchizoaffective disorder-bipolar type

MYO1G STAB2

2.50e-03161382EFO_0009965
Diseaseretinal vasculature measurement

RARB SPTBN1 ITGA1 PRAG1 FZD6 ABHD5 ZNF804B PLCL1

3.07e-035171388EFO_0010554
Diseasebreast carcinoma (is_marker_for)

KLK6 PLK1 PLK3

3.69e-03661383DOID:3459 (is_marker_for)
Diseasesex interaction measurement, cerebral amyloid angiopathy

ADH1B ADH1C

4.30e-03211382EFO_0006790, EFO_0008343
Diseasepulse pressure measurement, alcohol drinking

CORO2A ADAMTS8 ATP2B1

4.36e-03701383EFO_0004329, EFO_0005763
Diseasetissue plasminogen activator measurement, coronary artery disease

SEC14L3 ATP2B1 SMG6

4.54e-03711383EFO_0001645, EFO_0004791

Protein segments in the cluster

PeptideGeneStartEntry
LVCNYEPPGNVKGKR

PI16

161

Q6UXB8
VKGKRPYQEGTPCSQ

PI16

171

Q6UXB8
EYDRCPNKGAQLDPK

AMER3

61

Q8N944
APQDPCYVEKTSDKV

SMG6

1106

Q86US8
KGPDITQQPCARYEA

CFAP54

1801

Q96N23
FKCEKYIQPPQRETE

CASS4

606

Q9NQ75
VGISYQPRKCKEENV

CRYBG3

691

Q68DQ2
LGATECINPQDYKKP

ADH1A

236

P07327
PPDGKSFREQQCEKY

ADAMTS8

581

Q9UP79
CYEVKTKGPSRPPLD

APOBEC3G

36

Q9HC16
LTGKCYVENADGKIP

BCORP1

121

Q8N888
LGATECINPQDYKKP

ADH1B

236

P00325
LGATECINPQDYKKP

ADH1C

236

P00326
KKAPDGTVIPNGYCD

DPF1

261

Q92782
ELKAEYRVSVPQCKP

DPH1

196

Q9BZG8
NCAYTSKILPPEKEG

ATP2B1

521

P20020
ERLCNNPEPKFGGKY

ADAMTS12

566

P58397
EDGNYCPPVKRERTS

RANBP3

111

Q9H6Z4
DYPVEDAFCKPQLVK

GPRC5A

276

Q8NFJ5
PPRVYKPCFVCQDKS

RARB

81

P10826
QVPPRGCYVAKEAGE

LRRC3C

46

A6NJW4
KVQYPDAKPVRCKCG

ARIH1

286

Q9Y4X5
GVPYEKKFCEGSQPR

AOAH

241

P28039
PEVVSKIAQYKRECP

PAX6

81

P26367
YVVNCVSGDAKPAPD

NPHS1

156

O60500
YEPKCPLGVDISKEV

OSGEPL1

386

Q9H4B0
KENCGIYFPEIKRDP

NT5DC1

176

Q5TFE4
VITPPYQVENCKGKE

LSM12

141

Q3MHD2
VCPTRYEGPKCEVDK

LRP1B

4346

Q9NZR2
IAYDVQCPKREKPSN

MCUB

141

Q9NWR8
IFQPTGKYKPGRCDD

RNGTT

441

O60942
KAAAKPREQEAVCPG

GPR179

2171

Q6PRD1
NIRIGIEGYPTCKEK

KCTD20

316

Q7Z5Y7
PQGAPDCQKVKVMYR

MMRN2

86

Q9H8L6
APGSVQKYKVRCTAE

ALOXE3

46

Q9BYJ1
LDPDYKVSKDPFQVC

SMPDL3B

31

Q92485
PKRVKALYNCVADNP

ASAP2

946

O43150
DCRKFPVPQKDGSAL

FANCM

1771

Q8IYD8
RKCEPKGPLINSEFY

GLB1

256

P16278
NKCFVKVPRHYDDPG

FOXG1

236

P55316
PCAKVRPYIAEGESD

KCNQ2

826

O43526
PKRFKDATEVGCQPL

MLH3

551

Q9UHC1
AQKKEVPLSGAPDRY

LMO7

576

Q8WWI1
KDGRYCQEPRGPTEA

LRPPRC

566

P42704
LEYACGIKAEVVGKP

LHPP

176

Q9H008
VEKPTCANGYPAVKV

MUC5AC

4891

P98088
ELTPINGREETPCYK

MRGPRX3

11

Q96LB0
IDKCGYKEPTPIQRQ

DDX23

406

Q9BUQ8
CKPKAPEGEETEFYV

DNAJC5

136

Q9H3Z4
QPKNRTGDVYKCPVG

ITGA1

71

P56199
PPYQKDGSKVEFCIR

PPP1R3A

196

Q16821
VEPEKRGKYVVCFDP

FBP1

106

P09467
VYFTCRAEGNPKPEI

PXDNL

251

A1KZ92
VVPPCRKLCEKVYSD

FZD6

91

O60353
GEKYRKQPCEEETLG

ICE1

1216

Q9Y2F5
EQTGRIEPNYPKVCG

CORO2B

71

Q9UQ03
CRVPESNPKAEVRYK

CDON

141

Q4KMG0
CETKVKRVPGASEYP

CDON

921

Q4KMG0
FGKPASKENCYDSVP

CORO2A

16

Q92828
VNYREPKSVCKAPEL

CUL2

376

Q13617
YKKALRTNPGCPAEV

CTR9

186

Q6PD62
RHCPYGQVNVKDPSK

C1orf53

121

Q5VUE5
DILVYKPPNCKAFRD

ATRNL1

606

Q5VV63
NNYEPRSGKFTCKVP

C1QB

151

P02746
CSDKEKRVPFPIGIA

DTHD1

226

Q6ZMT9
EKVYGECSQKGPVPF

HASPIN

461

Q8TF76
VCKVDKQNRAGYSPI

KANK2

691

Q63ZY3
PQKVFSYSERAPGKC

KIAA1210

1271

Q9ULL0
YEIKEGDCPVQSGKT

KNG1

76

P01042
PNIVDCYIARPTEKK

GJB3

171

O75712
TDPDGNPKCLTKINY

SEC14L3

246

Q9UDX4
TDPDGNPKCLTKINY

SEC14L4

246

Q9UDX3
TDPDGNPKCLTKINY

SEC14L6

246

B5MCN3
ADKCVNPETKRPYTV

SBDS

116

Q9Y3A5
KDGVCVRVYTPVGKA

NPEPPS

261

P55786
CGINYVPDDKKPNGR

MTHFD1

236

P11586
NSPYEGPFCKKEVSA

CNTNAP5

986

Q8WYK1
PKERGPSAAEVFKCV

KBTBD6

251

Q86V97
GEEINEISYPKGKCS

PTPN13

2011

Q12923
VPPAEYRLCNGSDKE

OSBPL5

71

Q9H0X9
QCEKGYFRAEKDPPS

EPHA6

311

Q9UF33
RPDDSCKPKSVYENF

NUTM2F

196

A1L443
RPDDSCKPKSVYENF

NUTM2G

196

Q5VZR2
KYRVKPSNSSCDPGA

MOSPD2

371

Q8NHP6
PKVPKQDNSSDCGVY

SENP7

981

Q9BQF6
YKGKNTGSNACVPRP

SORL1

1011

Q92673
GENLVRYKKEPSGCP

PRDM15

891

P57071
RYKKEPSGCPVCGKV

PRDM15

896

P57071
LNFPKYCEPVVKGEA

ORC5

231

O43913
YCESHAKARVKPPEG

PDLIM4

301

P50479
AKARVKPPEGYDVVA

PDLIM4

306

P50479
TNRKVPYCVKFNPDE

CDC40

371

O60508
NLVVKENCSPKEEPY

SLC5A3

551

P53794
CFPRVKVGNEYVTKG

MYH3

401

P11055
NELCPKNVPKREYSV

PRDM1

236

O75626
TAVIPCFPYARQDKK

PRPS1L1

86

P21108
YCKAVSCGKPAIPEN

SVEP1

1841

Q4LDE5
TDGEGYKPCDPQVIR

SPTBN1

596

Q01082
VPCTYKKEPVRISNG

ABHD5

46

Q8WTS1
KEPDIKPQKDTGCYI

BROX

396

Q5VW32
PQCPSGRVYVLKFKA

ADRM1

86

Q16186
FKKGRPYSVPPCVEE

NCAPH2

331

Q6IBW4
VPEKIKTDNGPGYCS

ERVK-25

701

P63136
DECAKPNKPGVYTRV

TMPRSS11E

396

Q9UL52
RKKTICGTPNYVAPE

PLK3

216

Q9H4B4
QCAVPAKDRVDCGYP

TFF3

31

Q07654
AKDRVDCGYPHVTPK

TFF3

36

Q07654
PKGACAKGDVIDPYV

PLCL1

736

Q15111
YDQPPKCDISGKEAI

XYLT1

251

Q86Y38
ACEAGPSPVYVKVKS

VSIG8

381

P0DPA2
NGPAYKAPRVAIEKQ

ZNF804B

131

A4D1E1
DTYRRCSVPPGADKK

RPS10P5

136

Q9NQ39
FRVKPEDSGKYTCVP

IGSF9B

291

Q9UPX0
TAVIPCFPYARQDKK

PRPS2

86

P11908
ERCLYVFPAKVEPAK

UBE2O

351

Q9C0C9
VDKRVQSCPDPAVYG

UBE2O

591

Q9C0C9
YICKDPKINDATQEP

TM2D1

56

Q9BX74
PGQEESDPRYKRNIC

SENP6

841

Q9GZR1
DGKYCDPINPCLRKI

STAB2

231

Q8WWQ8
PNYCVEDKKLGIPGT

WNT16

291

Q9UBV4
CQEKQVAYCPSGKPE

ROS1

2316

P08922
TLKFTEGKGYQPCDP

SPTB

591

P11277
AAACEAGPSPVYVKV

SNHG28

76

P0DPA3
DPGSTYAVKICKAPE

PRAG1

1016

Q86YV5
ASREPYKNQPEKTCV

YTHDC1

121

Q96MU7
AAASPYPKRKQICEL

TNKS2

371

Q9H2K2
PVLTQAECKASYPGK

PRSS3

221

P35030
SPPYQEACTLKRKGQ

FTSJ1

271

Q9UET6
IQTEEKPYPCTGYRK

ZNF112

251

Q9UJU3
EKPYVCPECGKAFIQ

ZNF41

646

P51814
RQKPFVCEAYVKGSE

ZNF792

156

Q3KQV3
TPQRDHTGEKPYACK

ZNF69

181

Q9UC07
RIYSLKVECGPKYPE

UBE2V2

61

Q15819
TEPKPCKGNEYGKII

ZNF227

221

Q86WZ6
TAVIPCFPYARQDKK

PRPS1

86

P60891
CSRETEKKYPQPKGQ

PIEZO1

2151

Q92508
VPEKIKTDNGPGYCS

ERVK-19

706

Q9WJR5
AEENPCKYNPGRKAS

ZNF354A

321

O60765
SYRKVKNGQAPETCP

ZSCAN29

471

Q8IWY8
TVPKGTICKEANVYP

POLR1B

86

Q9H9Y6
PPQDSAVIKAGYCVK

PLEKHA1

186

Q9HB21
VREQYTAKPQKCPGK

SORCS1

781

Q8WY21
GEKPYQCPECEKTFR

ZNF425

606

Q6IV72
NRENKPTCYPKAEIS

USP8

741

P40818
IYNDQKVCASEKPPK

USP5

831

P45974
VRTHTGEKPYKCPEE

ZNF76

216

P36508
DGCPAVKKQENYIPD

ZFYVE9

276

O95405
VKKVYRPEDCFTVNP

WDR64

681

B1ANS9
PQSREPGKVFVCDAY

ZNF628

241

Q5EBL2
ERKKTLCGTPNYIAP

PLK1

206

P53350
IPCGSKEKPGVYTNV

KLK6

216

Q92876
VESRGQPVKIYACKA

KIAA2013

511

Q8IYS2
QSKEPAYVRCIKPND

MYO1C

616

O00159
AYVRCIKPNDAKQPG

MYO1C

621

O00159
PFYVRCIKPNEDKVA

MYO1G

596

B0I1T2