Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionRNA-directed DNA polymerase activity

ERVK-6 ERVK-7 ERVK-10 TEP1 ERVK-8 ERVK-11

1.49e-09141826GO:0003964
GeneOntologyMolecularFunctionRNA-DNA hybrid ribonuclease activity

ERVK-6 ERVK-7 ERVK-10 ERVK-8 ERVK-11

2.63e-08111825GO:0004523
GeneOntologyMolecularFunctionDNA polymerase activity

ERVK-6 POLG ERVK-7 ERVK-10 TEP1 ERVK-8 ERVK-11

4.63e-08381827GO:0034061
GeneOntologyMolecularFunctionRNA stem-loop binding

ERVK-6 ERVK-7 ERVK-10 ERVK-8 ERVK-11

1.08e-06211825GO:0035613
GeneOntologyMolecularFunctioncatalytic activity, acting on DNA

ERVK-6 SMARCA5 POLG WRN ERVK-7 ERVK-10 TEP1 ERVK-8 SMARCA1 NAV2 ASCC3 ERVK-11

5.36e-0626218212GO:0140097
GeneOntologyMolecularFunctionDNA-binding transcription factor activity, RNA polymerase II-specific

FOXO3 ZNF486 FOXO6 GCM2 SPI1 ZNF337 TSHZ2 FOXN4 ZNF875 NTN3 ZNF254 ZNF629 ZNF343 ZNF619 FOXN3 ZNF595 ZNF248 ZNF10 ZNF514 ZNF18 THRB ZFHX4 ZNF283 ZNF726P1 SKOR1 ZNF479 FOXO4 ZNF700 ZNF679 ZNF726

1.18e-05141218230GO:0000981
GeneOntologyMolecularFunctionRNA endonuclease activity, producing 5'-phosphomonoesters

ERVK-6 ERVK-7 ERVK-10 ERVK-8 ERVK-11

2.05e-05371825GO:0016891
GeneOntologyMolecularFunctionaspartic-type endopeptidase activity

ERVK-6 ERVK-7 ERVK-10 ERVK-8 ERVK-18

2.05e-05371825GO:0004190
GeneOntologyMolecularFunctionaspartic-type peptidase activity

ERVK-6 ERVK-7 ERVK-10 ERVK-8 ERVK-18

2.34e-05381825GO:0070001
GeneOntologyMolecularFunctionendonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters

ERVK-6 ERVK-7 ERVK-10 ERVK-8 ERVK-11

6.03e-05461825GO:0016893
GeneOntologyMolecularFunctionnucleotidyltransferase activity

ERVK-6 POLG ERVK-7 ERVK-10 TEP1 PARP6 ERVK-8 ERVK-11

7.84e-051521828GO:0016779
GeneOntologyMolecularFunctiontriacylglycerol lipase activity

PLB1 LIPK ABHD5 LIPM

8.53e-05261824GO:0004806
GeneOntologyMolecularFunctionRNA polymerase II transcription regulatory region sequence-specific DNA binding

FOXO3 ZNF486 FOXO6 GCM2 SPI1 ZNF337 ZNF875 NTN3 ZNF254 ZNF629 ZNF343 ZNF619 ZNF595 ZNF248 ZNF10 ZNF514 ZNF18 THRB ZFHX4 ZNF283 ZNF726P1 SKOR1 ZNF479 FOXO4 ZNF700 ZNF679 ZNF726 UTY

1.41e-04145918228GO:0000977
GeneOntologyMolecularFunctionbenzoate-CoA ligase activity

ACSM2A ACSM2B

2.46e-0431822GO:0018858
GeneOntologyMolecularFunction3'-5' DNA helicase activity

WRN NAV2 ASCC3

3.82e-04161823GO:0043138
GeneOntologyMolecularFunctiondecanoate-CoA ligase activity

ACSM2A ACSM2B

4.90e-0441822GO:0102391
GeneOntologyMolecularFunctionRNA endonuclease activity

ERVK-6 ERVK-7 ERVK-10 ERVK-8 ERVK-11

7.78e-04791825GO:0004521
GeneOntologyMolecularFunctioncis-regulatory region sequence-specific DNA binding

FOXO3 ZNF486 FOXO6 GCM2 SPI1 FOXN4 NTN3 ZNF254 ZNF629 FOXN3 ZNF595 ZNF514 ZNF18 THRB ZFHX4 ZNF283 ZNF726P1 SKOR1 ZNF479 FOXO4 ZNF679 ZNF726 UTY

1.29e-03127118223GO:0000987
GeneOntologyBiologicalProcessDNA integration

ERVK-6 ERVK-7 ERVK-10 ERVK-8 ERVK-11

6.50e-08131845GO:0015074
GeneOntologyBiologicalProcessDNA synthesis involved in DNA repair

ERVK-6 WRN ERVK-7 ERVK-10 ERVK-8 ERVK-11

4.18e-06481846GO:0000731
GeneOntologyBiologicalProcesspositive regulation of dendritic spine development

FOXO6 SLC30A1 LPAR1 MFN1 CAPRIN2 EEF2K

3.79e-05701846GO:0060999
GeneOntologyBiologicalProcessultradian rhythm

ENOX1 ENOX2

7.92e-0521842GO:0007624
DomainKRAB

ZNF486 ZNF337 ZNF875 ZNF254 ZNF343 ZNF595 ZNF248 ZNF10 ZNF514 ZNF18 ZNF283 ZNF479 ZNF700 ZNF679 ZNF726

1.58e-0635817615PS50805
DomainKRAB

ZNF486 ZNF337 ZNF875 ZNF254 ZNF343 ZNF595 ZNF248 ZNF10 ZNF514 ZNF18 ZNF283 ZNF479 ZNF700 ZNF679 ZNF726

1.58e-0635817615PF01352
DomainKRAB

ZNF486 ZNF337 ZNF875 ZNF254 ZNF343 ZNF595 ZNF248 ZNF10 ZNF514 ZNF18 ZNF283 ZNF479 ZNF700 ZNF679 ZNF726

2.30e-0636917615SM00349
DomainKRAB

ZNF486 ZNF337 ZNF875 ZNF254 ZNF343 ZNF595 ZNF248 ZNF10 ZNF514 ZNF18 ZNF283 ZNF479 ZNF700 ZNF679 ZNF726

2.37e-0637017615IPR001909
Domainzf-C2H2

ZNF486 ZNF337 TSHZ2 ZNF875 ZNF254 ZNF629 ZNF343 ZNF619 ZNF595 ZNF248 ZNF10 ZNF514 ZNF18 ZFHX4 ZNF283 ZNF479 ZNF700 ZNF679 ZNF726

3.07e-0569317619PF00096
DomainZINC_FINGER_C2H2_2

ZNF486 ZNF337 TSHZ2 ZNF875 ZNF254 ZNF629 ZNF343 ZNF619 ZNF595 ZNF248 ZNF10 ZNF514 ZNF18 ZFHX4 ZNF804B ZNF283 ZNF479 ZNF700 ZNF679 ZNF726

4.40e-0577517620PS50157
DomainZINC_FINGER_C2H2_1

ZNF486 ZNF337 TSHZ2 ZNF875 ZNF254 ZNF629 ZNF343 ZNF619 ZNF595 ZNF248 ZNF10 ZNF514 ZNF18 ZFHX4 ZNF804B ZNF283 ZNF479 ZNF700 ZNF679 ZNF726

4.56e-0577717620PS00028
DomainZnf_C2H2

ZNF486 ZNF337 TSHZ2 ZNF875 ZNF254 ZNF629 ZNF343 ZNF619 ZNF595 ZNF248 ZNF10 ZNF514 ZNF18 ZFHX4 ZNF804B ZNF283 ZNF479 ZNF700 ZNF679 ZNF726

7.44e-0580517620IPR007087
DomainTF_fork_head_CS_1

FOXO3 FOXO6 FOXN4 FOXN3 FOXO4

7.82e-05471765IPR018122
DomainZnF_C2H2

ZNF486 ZNF337 TSHZ2 ZNF875 ZNF254 ZNF629 ZNF343 ZNF619 ZNF595 ZNF248 ZNF10 ZNF514 ZNF18 ZFHX4 ZNF804B ZNF283 ZNF479 ZNF700 ZNF679 ZNF726

7.83e-0580817620SM00355
DomainSLIDE

SMARCA5 SMARCA1

8.83e-0521762IPR015195
DomainISWI_HAND-dom

SMARCA5 SMARCA1

8.83e-0521762IPR015194
DomainNCKAP5_C

NCKAP5 NCKAP5L

8.83e-0521762IPR032769
DomainNckap5l

NCKAP5 NCKAP5L

8.83e-0521762IPR026163
DomainNCKAP5

NCKAP5 NCKAP5L

8.83e-0521762PF15246
DomainFAM217

FAM217A FAM217B

8.83e-0521762IPR029266
DomainSLIDE

SMARCA5 SMARCA1

8.83e-0521762PF09111
DomainHAND

SMARCA5 SMARCA1

8.83e-0521762PF09110
DomainFAM217

FAM217A FAM217B

8.83e-0521762PF15344
DomainISWI

SMARCA5 SMARCA1

8.83e-0521762IPR029915
DomainFH

FOXO3 FOXO6 FOXN4 FOXN3 FOXO4

9.57e-05491765SM00339
DomainFORK_HEAD_1

FOXO3 FOXO6 FOXN4 FOXN3 FOXO4

9.57e-05491765PS00657
DomainFORK_HEAD_2

FOXO3 FOXO6 FOXN4 FOXN3 FOXO4

9.57e-05491765PS00658
DomainFork_head_dom

FOXO3 FOXO6 FOXN4 FOXN3 FOXO4

9.57e-05491765IPR001766
DomainFORK_HEAD_3

FOXO3 FOXO6 FOXN4 FOXN3 FOXO4

9.57e-05491765PS50039
DomainForkhead

FOXO3 FOXO6 FOXN4 FOXN3 FOXO4

9.57e-05491765PF00250
DomainZnf_C2H2-like

ZNF486 ZNF337 TSHZ2 ZNF875 ZNF254 ZNF629 ZNF343 ZNF619 ZNF248 ZNF10 ZNF514 ZNF18 ZFHX4 ZNF804B ZNF283 ZNF479 ZNF700 ZNF679 ZNF726

1.90e-0479617619IPR015880
Domain-

ZNF486 ZNF337 ZNF875 ZNF254 ZNF629 ZNF343 ZNF619 ZNF248 ZNF10 ZNF514 ZNF18 ZFHX4 ZNF283 ZNF479 ZNF700 ZNF679 ZNF726

2.42e-04679176173.30.160.60
DomainDBINO

SMARCA5 SMARCA1

2.63e-0431762IPR020838
DomainFOXO-TAD

FOXO3 FOXO4

2.63e-0431762IPR032067
DomainDBINO

SMARCA5 SMARCA1

2.63e-0431762PF13892
DomainFOXO-TAD

FOXO3 FOXO4

2.63e-0431762PF16676
DomainZnf_C2H2/integrase_DNA-bd

ZNF486 ZNF337 ZNF875 ZNF254 ZNF629 ZNF343 ZNF619 ZNF248 ZNF10 ZNF514 ZNF18 ZFHX4 ZNF283 ZNF479 ZNF700 ZNF679 ZNF726

3.11e-0469417617IPR013087
DomainCAP

CLEC18A CLEC18B CLEC18C

3.44e-04151763PF00188
DomainSCP

CLEC18A CLEC18B CLEC18C

3.44e-04151763SM00198
DomainAllrgn_V5/Tpx1

CLEC18A CLEC18B CLEC18C

3.44e-04151763IPR001283
Domain-

CLEC18A CLEC18B CLEC18C

3.44e-041517633.40.33.10
DomainCAP_domain

CLEC18A CLEC18B CLEC18C

3.44e-04151763IPR014044
DomainEGF-like_dom

PCSK5 CLEC18A CLEC18B LAMA2 CLEC18C VWDE ADAM22 MALRD1 OTOG

6.06e-042491769IPR000742
DomainC-type_lectin_CS

MRC1 CLEC18A CLEC18B CLEC18C

7.06e-04431764IPR018378
DomainTF_fork_head_CS_2

FOXO3 FOXN4 FOXN3 FOXO4

9.13e-04461764IPR030456
DomainLipase_euk

LIPK LIPM

1.29e-0361762IPR025483
DomainAbhydro_lipase

LIPK LIPM

1.29e-0361762PF04083
DomainAB_hydrolase_lipase

LIPK LIPM

1.29e-0361762IPR006693
DomainEGF

PCSK5 CLEC18A CLEC18B LAMA2 CLEC18C VWDE ADAM22 MALRD1

1.77e-032351768SM00181
DomainGalactose-bd-like

PCSK5 NTN3 LAMA2 ZZEF1 FBXO44

1.96e-03941765IPR008979
PathwayREACTOME_AMINO_ACID_CONJUGATION

GLYATL2 ACSM2A ACSM2B

5.50e-0591253M26968
PathwayREACTOME_AKT_PHOSPHORYLATES_TARGETS_IN_THE_NUCLEUS

FOXO3 FOXO6 FOXO4

7.80e-05101253M27095
PathwayREACTOME_AKT_PHOSPHORYLATES_TARGETS_IN_THE_NUCLEUS

FOXO3 FOXO6 FOXO4

7.80e-05101253MM14778
PathwayREACTOME_REGULATION_OF_LOCALIZATION_OF_FOXO_TRANSCRIPTION_FACTORS

FOXO3 FOXO6 FOXO4

1.41e-04121253MM15657
PathwayREACTOME_REGULATION_OF_LOCALIZATION_OF_FOXO_TRANSCRIPTION_FACTORS

FOXO3 FOXO6 FOXO4

1.41e-04121253M27939
Pubmed

The mannose receptor mediates uptake of soluble but not of cell-associated antigen for cross-presentation.

MRC1 CLEC18A CLEC18B CLEC18C

8.09e-104187416709836
Pubmed

Human CLEC18 Gene Cluster Contains C-type Lectins with Differential Glycan-binding Specificity.

CLEC18A CLEC18B CLEC18C

1.53e-073187326170455
Pubmed

The C-type lectin-like domain superfamily.

CLEC18A CLEC18B CLEC18C

1.53e-073187316336259
Pubmed

Endosomal TLR3 co-receptor CLEC18A enhances host immune response to viral infection.

CLEC18A CLEC18B CLEC18C

1.53e-073187333603190
Pubmed

Spatial and temporal expression of FoxO transcription factors in the developing and adult murine brain.

FOXO3 FOXO6 FOXO4

6.09e-074187316326148
Pubmed

Many human endogenous retrovirus K (HERV-K) proviruses are unique to humans.

ERVK-6 ERVK-7 ERVK-10

6.09e-074187310469592
Pubmed

Quantitation of HERV-K env gene expression and splicing in human breast cancer.

ERVK-6 ERVK-7 ERVK-18

1.52e-065187312629516
Pubmed

The KRAB zinc finger protein RSL1 modulates sex-biased gene expression in liver and adipose tissue to maintain metabolic homeostasis.

ZNF254 ZNF595 ZNF726

1.52e-065187324190968
Pubmed

A pair of mouse KRAB zinc finger proteins modulates multiple indicators of female reproduction.

ZNF254 ZNF595 ZNF726

1.52e-065187320042539
Pubmed

A Degradation Motif in STAU1 Defines a Novel Family of Proteins Involved in Inflammation.

PCNP DNAJC13 ILF3 ZNF629 EPB41L3 TRIP4 CENPP FAM120C TNRC6A MACF1 ZMYM1 DHRS2 ASCC3 PALLD VCL WDR48

2.16e-067241871636232890
Pubmed

Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.

SMARCA5 FBF1 ZNF629 DGKE EPB41L3 TEP1 ZZEF1 NCKAP5L TRIP4 ITIH4 KSR1 ZFHX4 FAM120C CAPRIN2 TNRC6A SMARCA1 MACF1 ASCC3 WDR62 WDR48

2.80e-0611161872031753913
Pubmed

FoxO transcription factors suppress Myc-driven lymphomagenesis via direct activation of Arf.

FOXO3 FOXO6 FOXO4

3.02e-066187317974917
Pubmed

FoxO transcription factors; Regulation by AKT and 14-3-3 proteins.

FOXO3 FOXO6 FOXO4

3.02e-066187321708191
Pubmed

The KRAB-zinc-finger protein ZFP708 mediates epigenetic repression at RMER19B retrotransposons.

ZNF254 ZNF595 ZNF726

3.02e-066187330846446
Pubmed

The KRAB zinc finger protein RSL1 regulates sex- and tissue-specific promoter methylation and dynamic hormone-responsive chromatin configuration.

ZNF254 ZNF595 ZNF726

5.27e-067187322801370
Pubmed

A revised nomenclature for transcribed human endogenous retroviral loci.

ERVK-6 ERVK-7 ERVK-10 ERVK-8 ERVK-18 ERVK-11

1.23e-0594187621542922
Pubmed

Comparative analysis of KRAB zinc finger proteins in rodents and man: evidence for several evolutionarily distinct subfamilies of KRAB zinc finger genes.

ZNF254 ZNF595 ZNF726

1.25e-059187310360839
Pubmed

Tagging genes with cassette-exchange sites.

ENOX1 ZNF254 FOXN3 ZNF595 UHMK1 NAV2 MACF1 ZMYM1 TOR1AIP1 ZNF726

1.51e-053351871015741177
Pubmed

Regulator of sex-limitation (Rsl) encodes a pair of KRAB zinc-finger genes that control sexually dimorphic liver gene expression.

ZNF254 ZNF595 ZNF679 ZNF726

1.73e-0529187414563677
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

FOXO3 CEP162 ZNF629 HNRNPUL1 EPB41L3 NCKAP5L PIK3R4 KSR1 SVIL NAV2 FAM83G MACF1 FOXO4 PALLD WDR62 OTOG

1.87e-058611871636931259
Pubmed

Comparative analyses of disease risk genes belonging to the acyl-CoA synthetase medium-chain (ACSM) family in human liver and cell lines.

ACSM2A ACSM2B

2.88e-052187219634011
Pubmed

Thyroid hormone receptor β1 stimulates ABCB4 to increase biliary phosphatidylcholine excretion in mice.

ABCB4 THRB

2.88e-052187229895698
Pubmed

Control of cell cycle exit and entry by protein kinase B-regulated forkhead transcription factors.

FOXO3 FOXO4

2.88e-052187211884591
Pubmed

Expression of tumor-associated macrophage in progression of human glioma.

MRC1 FCGR3A

2.88e-052187225182001
Pubmed

Decreased basal mucus secretion by Slp2-a-deficient gastric surface mucous cells.

SYTL2 RAB27B

2.88e-052187216716193
Pubmed

The FoxO4/DKK3 axis represses IFN-γ expression by Th1 cells and limits antimicrobial immunity.

FOXO3 FOXO4

2.88e-052187236106640
Pubmed

The L513S polymorphism in medium-chain acyl-CoA synthetase 2 (MACS2) is associated with risk factors of the metabolic syndrome in a Caucasian study population.

ACSM2A ACSM2B

2.88e-052187216521160
Pubmed

Modulation of glutamine metabolism by the PI(3)K-PKB-FOXO network regulates autophagy.

FOXO3 FOXO4

2.88e-052187222820375
Pubmed

How lamina-associated polypeptide 1 (LAP1) activates Torsin.

TOR1A TOR1AIP1

2.88e-052187225149450
Pubmed

The preventive effect of β-carotene on denervation-induced soleus muscle atrophy in mice.

FOXO3 USP14

2.88e-052187223046823
Pubmed

FOXO forkhead transcription factors induce G(2)-M checkpoint in response to oxidative stress.

FOXO3 FOXO4

2.88e-052187212048180
Pubmed

Analyses of the genetic diversity and protein expression variation of the acyl: CoA medium-chain ligases, ACSM2A and ACSM2B.

ACSM2A ACSM2B

2.88e-052187229948332
Pubmed

Nuclear envelope-localized torsinA-LAP1 complex regulates hepatic VLDL secretion and steatosis.

TOR1A TOR1AIP1

2.88e-052187231408437
Pubmed

Transcriptional regulation of the HIV-1 inhibitory factor human mannose receptor 1 by the myeloid-specific transcription factor PU.1.

MRC1 SPI1

2.88e-052187238078733
Pubmed

Central FoxO3a and FoxO6 expression is down-regulated in obesity induced diabetes but not in aging.

FOXO3 FOXO6

2.88e-052187222187289
Pubmed

Deubiquitylation and stabilization of Acf7 by ubiquitin carboxylterminal hydrolase 14 (USP14) is critical for NSCLC migration.

USP14 MACF1

2.88e-052187233737492
Pubmed

Expression and localisation of FoxO3 and FoxO4 in human placenta and fetal membranes.

FOXO3 FOXO4

2.88e-052187220934750
Pubmed

Interferon-alpha-induced endogenous superantigen. a model linking environment and autoimmunity.

ERVK-6 ERVK-18

2.88e-052187211672541
Pubmed

Correlations of Foxo3 and Foxo4 expressions with clinicopathological features and prognosis of bladder cancer.

FOXO3 FOXO4

2.88e-052187228554751
Pubmed

Family-wide characterization of the DENN domain Rab GDP-GTP exchange factors.

DENND5B DENND2A RAB18 RAB27B

4.65e-0537187420937701
Pubmed

An antibody-based proximity labeling map reveals mechanisms of SARS-CoV-2 inhibition of antiviral immunity.

SYTL2 DGKE FNDC3A SLC30A1 NCKAP5L TRIP4 ITPR2 USP14 ARFGAP3 TNRC6A ZMYM1 TOR1AIP1 VCL WDR62

4.72e-057331871434672954
Pubmed

Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.

DNAJC13 ILF3 PDE7A TOR1A MRPL13 DGKE FNDC3A HNRNPUL1 EPB41L3 SLC30A1 NCKAP5L TRIP4 ITPR2 NDUFA12 MACF1 EEF2K ASCC3 TOR1AIP1 PBXIP1 VCL WDR62

5.53e-0514871872133957083
Pubmed

Genome-wide association analysis of susceptibility and clinical phenotype in multiple sclerosis.

FOXO3 PCSK5 NCKAP5 SVIL

5.75e-0539187419010793
Pubmed

Talin 1 and 2 are required for myoblast fusion, sarcomere assembly and the maintenance of myotendinous junctions.

LAMA2 ITGAV VCL

6.64e-0515187319793892
Pubmed

Expansion and diversification of KRAB zinc-finger genes within a cluster including Regulator of sex-limitation 1 and 2.

ZNF254 ZNF595 ZNF726

6.64e-0515187315885501
Pubmed

Long-term potentiation modulates synaptic phosphorylation networks and reshapes the structure of the postsynaptic interactome.

GRIN1 EPB41L3 ADAM22 ITIH4 MAP3K5 ARVCF MACF1 AGAP2

6.91e-05251187827507650
Pubmed

Identification of new ciliary signaling pathways in the brain and insights into neurological disorders.

DENND5B GABRG2 DGKE SLC30A1 ADAM22 ARVCF ARFGAP3 OSTF1 RAB27B WDR48

7.46e-054051871038187761
Pubmed

Identification of forkhead transcription factors in cortical and dopaminergic areas of the adult murine brain.

FOXO3 FOXO6 FOXO4

8.14e-0516187316376864
Pubmed

A mutant allele encoding DNA binding-deficient FoxO1 differentially regulates hepatic glucose and lipid metabolism.

FOXO3 FOXO4

8.60e-053187225576059
Pubmed

A unique redox-sensing sensor II motif in TorsinA plays a critical role in nucleotide and partner binding.

TOR1A TOR1AIP1

8.60e-053187220861018
Pubmed

Endothelial FoxO proteins impair insulin sensitivity and restrain muscle angiogenesis in response to a high-fat diet.

FOXO3 FOXO4

8.60e-053187227235148
Pubmed

SPOCK: Master regulator of malignant tumors (Review).

SPOCK2 SPOCK3

8.60e-053187239392048
Pubmed

FoxO6, a novel member of the FoxO class of transcription factors with distinct shuttling dynamics.

FOXO3 FOXO6

8.60e-053187212857750
Pubmed

Epigenetic control of SPI1 gene by CTCF and ISWI ATPase SMARCA5.

SMARCA5 SPI1

8.60e-053187224498324
Pubmed

FoxO transcription factors 1 regulate mouse preimplantation embryo development.

FOXO3 FOXO4

8.60e-053187231396850
Pubmed

FOXO1, FOXO3, AND FOXO4 are differently expressed during mouse oocyte maturation and preimplantation embryo development.

FOXO3 FOXO4

8.60e-053187225929834
Pubmed

Functional regulation of FoxO1 in neural stem cell differentiation.

FOXO3 FOXO4

8.60e-053187226470727
Pubmed

Deletion of FoxO1, 3, and 4 in Osteoblast Progenitors Attenuates the Loss of Cancellous Bone Mass in a Mouse Model of Type 1 Diabetes.

FOXO3 FOXO4

8.60e-053187227491024
Pubmed

FOXO transcription factors are mechanosensitive and their regulation is altered with aging in the respiratory pump.

FOXO3 FOXO4

8.60e-053187218272820
Pubmed

Loss of FoxOs in muscle reveals sex-based differences in insulin sensitivity but mitigates diet-induced obesity.

FOXO3 FOXO4

8.60e-053187231767172
Pubmed

Inhibition of FoxO transcriptional activity prevents muscle fiber atrophy during cachexia and induces hypertrophy.

FOXO3 FOXO4

8.60e-053187222102632
Pubmed

Identification of an active reverse transcriptase enzyme encoded by a human endogenous HERV-K retrovirus.

ERVK-6 ERVK-11

8.60e-05318729971820
Pubmed

Forkhead BoxO transcription factors restrain exercise-induced angiogenesis.

FOXO3 FOXO4

8.60e-053187225063823
Pubmed

FOXOs attenuate bone formation by suppressing Wnt signaling.

FOXO3 FOXO4

8.60e-053187223867625
Pubmed

The FoxO transcription factors and metabolic regulation.

FOXO3 FOXO4

8.60e-053187218022395
Pubmed

Forkhead box O transcription factors in chondrocytes regulate endochondral bone formation.

FOXO3 FOXO4

8.60e-053187226232637
Pubmed

Altered Plasma Profile of Antioxidant Proteins as an Early Correlate of Pancreatic β Cell Dysfunction.

FOXO3 FOXO4

8.60e-053187226917725
Pubmed

FoxO-mediated defense against oxidative stress in osteoblasts is indispensable for skeletal homeostasis in mice.

FOXO3 FOXO4

8.60e-053187220142101
Pubmed

Deletion of hepatic FoxO1/3/4 genes in mice significantly impacts on glucose metabolism through downregulation of gluconeogenesis and upregulation of glycolysis.

FOXO3 FOXO4

8.60e-053187224015318
Pubmed

Control of cyclin G2 mRNA expression by forkhead transcription factors: novel mechanism for cell cycle control by phosphoinositide 3-kinase and forkhead.

FOXO3 FOXO4

8.60e-053187214966295
Pubmed

Metabolic Regulation of Stem Cells and Differentiation: A Forkhead Box O Transcription Factor Perspective.

FOXO3 FOXO4

8.60e-053187232847377
Pubmed

FoxO family members in cancer.

FOXO3 FOXO4

8.60e-053187221613825
Pubmed

Common mechanism for oncogenic activation of MLL by forkhead family proteins.

FOXO3 FOXO4

8.60e-053187212393557
Pubmed

FOXO transcription factors enforce cell cycle checkpoints and promote survival of hematopoietic cells after DNA damage.

FOXO3 FOXO4

8.60e-053187219671690
Pubmed

Acidosis overrides oxygen deprivation to maintain mitochondrial function and cell survival.

SYTL2 MFN1

8.60e-053187224686499
Pubmed

FOXO transcription factors protect against the diet-induced fatty liver disease.

FOXO3 FOXO4

8.60e-053187228300161
Pubmed

Binding kinetics of human ISWI chromatin-remodelers to DNA repair sites elucidate their target location mechanism.

SMARCA5 SMARCA1

8.60e-053187221738833
Pubmed

Cloning and characterization of the murine Imitation Switch (ISWI) genes: differential expression patterns suggest distinct developmental roles for Snf2h and Snf2l.

SMARCA5 SMARCA1

8.60e-053187211359880
Pubmed

FoxOs are lineage-restricted redundant tumor suppressors and regulate endothelial cell homeostasis.

FOXO3 FOXO4

8.60e-053187217254969
Pubmed

Cell-specific effects of Dyt1 knock-out on sensory processing, network-level connectivity, and motor deficits.

TOR1A GRIN1

8.60e-053187234119482
Pubmed

Dynamic regulation of hepatic lipid metabolism by torsinA and its activators.

TOR1A TOR1AIP1

8.60e-053187238194265
Pubmed

Candidate gene study of FOXO1, FOXO4, and FOXO6 reveals no association with human longevity in Germans.

FOXO6 FOXO4

8.60e-053187221388494
Pubmed

Identification of the differential distribution patterns of mRNAs and consensus binding sequences for mouse DAF-16 homologues.

FOXO3 FOXO4

8.60e-053187210880363
Pubmed

Integrated control of hepatic lipogenesis versus glucose production requires FoxO transcription factors.

FOXO3 FOXO4

8.60e-053187225307742
Pubmed

Genome-wide screening, cloning, chromosomal assignment, and expression of full-length human endogenous retrovirus type K.

ERVK-6 ERVK-18

8.60e-053187210516026
Pubmed

Dysregulation of FOXO transcription factors in Epstein-Barr virus-associated gastric carcinoma.

FOXO3 FOXO4

8.60e-053187231712122
Pubmed

Polymorphisms in FOXO gene family and association analysis with BMI.

FOXO3 FOXO4

8.60e-053187216571842
Pubmed

FoxO transcription factors are required for hepatic HDL cholesterol clearance.

FOXO3 FOXO4

8.60e-053187229408809
Pubmed

AFX-like Forkhead transcription factors mediate cell-cycle regulation by Ras and PKB through p27kip1.

FOXO3 FOXO4

8.60e-053187210783894
Pubmed

The transcription of FOXO genes is stimulated by FOXO3 and repressed by growth factors.

FOXO3 FOXO4

8.60e-053187219244250
Pubmed

FOXO4 transcriptional activity is regulated by monoubiquitination and USP7/HAUSP.

FOXO3 FOXO4

8.60e-053187216964248
Pubmed

Expression of forkhead transcription factors in human granulosa cells.

FOXO3 FOXO4

8.60e-053187218692812
Pubmed

Archvillin, a muscle-specific isoform of supervillin, is an early expressed component of the costameric membrane skeleton.

SVIL VCL

8.60e-053187212711699
Pubmed

Expression of kinase suppressor of Ras in the normal adult and embryonic mouse.

KSR1 VCL

8.60e-053187212133899
Pubmed

Mitochondria Define Intestinal Stem Cell Differentiation Downstream of a FOXO/Notch Axis.

FOXO3 FOXO4

8.60e-053187233147486
Pubmed

Expression of FKHR, FKHRL1, and AFX genes in the rodent ovary: evidence for regulation by IGF-I, estrogen, and the gonadotropins.

FOXO3 FOXO4

8.60e-053187211875118
Pubmed

CD97 amplifies LPA receptor signaling and promotes thyroid cancer progression in a mouse model.

LPAR1 THRB

8.60e-053187222797060
Pubmed

FOXO protects against age-progressive axonal degeneration.

FOXO3 FOXO4

8.60e-053187229178390
Pubmed

Dystonia-causing mutant torsinA inhibits cell adhesion and neurite extension through interference with cytoskeletal dynamics.

TOR1A TOR1AIP1

8.60e-053187216361107
Pubmed

FOXO responses to Porphyromonas gingivalis in epithelial cells.

FOXO3 FOXO4

8.60e-053187225958948
GeneFamilyZinc fingers C2H2-type|ZF class homeoboxes and pseudogenes

ZNF486 ZNF337 TSHZ2 ZNF875 ZNF254 ZNF629 ZNF343 ZNF619 ZNF595 ZNF248 ZNF10 ZNF514 ZNF18 ZNF283 ZNF479 ZNF700 ZNF679 ZNF726

4.32e-067181311828
GeneFamilyForkhead boxes

FOXO3 FOXO6 FOXN4 FOXN3 FOXO4

1.43e-05431315508
GeneFamilyC-type lectin domain family

MRC1 CLEC18A CLEC18B CLEC18C

3.69e-04471314494
GeneFamilySPARC family

SPOCK2 SPOCK3

1.42e-03813121278
GeneFamilyArfGAPs

ACAP1 ARFGAP3 AGAP2

1.73e-03331313395
ToppCellrenal_cortex_nuclei|World / Celltypes from Cells and Nuclei per compartment and clinical group

DENND5B PDE7A NCKAP5 EPB41L3 BABAM2 TRPM3 SVIL TNRC6A MACF1 ACSM2A ACSM2B

3.80e-1019217911e8cc4d08fcfceeab75a02558817e4ccd7dbafe3a
ToppCellLPS_IL1RA_TNF-Mesenchymal_myocytic-Myofibroblastic-MatrixFB_->_Myofibroblast|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

PCSK5 DENND2A TSHZ2 SERPINF1 SYTL2 LAMA2 ADAMTSL3 ADAM22 ZFHX4 PALLD

9.03e-092001791009537dc25f8b8b4654a7c183827ee1522a41a4e0
ToppCellLPS_only-Stromal_mesenchymal-Lung_smooth_muscle-MatrixFB_->_Myofibroblast|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PCSK5 TSHZ2 SERPINF1 SYTL2 LAMA2 ADAMTSL3 ADAM22 ZFHX4 PALLD

5.85e-08183179912daaea821e49bc94a01e2496331e92a80d27339
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

TSHZ2 SERPINF1 LAMA2 ADAMTSL3 LPAR1 MAP3K5 ZFHX4 NAV2 PALLD

9.23e-08193179909a9ab029f01234459a88e3e994fe90ef4cbb8c6
ToppCellLPS_anti-TNF-Mesenchymal_myocytic-Myofibroblastic-MatrixFB_->_Myofibroblast|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

PCSK5 DENND2A TSHZ2 SERPINF1 SYTL2 LAMA2 ADAM22 ZFHX4 PALLD

1.20e-07199179938cfd367ee8c074c11ba54edeb7a001e375e2687
ToppCellLPS_IL1RA-Mesenchymal_myocytic-Myofibroblastic-MatrixFB_->_Myofibroblast|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

PCSK5 GABRG2 TSHZ2 SERPINF1 SYTL2 ADAMTSL3 ADAM22 ZFHX4 PALLD

1.20e-0719917996b3a0e5d52a30d0eed30e6a670f5b53bc233f70c
ToppCellLPS_IL1RA_TNF-Mesenchymal_myocytic-Myofibroblastic|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

PCSK5 TSHZ2 SERPINF1 SYTL2 ADAM22 ZFHX4 SVIL PALLD VCL

1.25e-07200179908bf8c00eee6468215edb3611296bfc8784c4d56
ToppCellLPS_only-Mesenchymal_myocytic-Myofibroblastic-MatrixFB_->_Myofibroblast|LPS_only / Treatment groups by lineage, cell group, cell type

PCSK5 TSHZ2 SERPINF1 SYTL2 LAMA2 ADAMTSL3 ADAM22 ZFHX4 PALLD

1.25e-072001799a9ff3210127000b3dd9e97136163c98c2b0817d7
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-proliferative_fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

TSHZ2 LAMA2 ZNF343 LPAR1 RGS16 ZFHX4 PLD5 PALLD

6.16e-071771798b872ee91e01265b101b81bd304cf6b95d5419e68
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

TSHZ2 LAMA2 ADAMTSL3 LPAR1 NAV2 PLD5 PALLD VCL

7.61e-07182179844764676ed3f51ba171ce63f669390392fa50a43
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

TSHZ2 LAMA2 ADAMTSL3 LPAR1 NAV2 PLD5 PALLD VCL

7.61e-071821798d82f59a3f930a840dde27dc6ab024f227a26d446
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive|renal_medulla_nuclei / Celltypes from Cells and Nuclei per compartment and clinical group

PDE7A TSHZ2 SYTL2 BABAM2 LPAR1 MAP3K5 SVIL MACF1

8.26e-071841798d2bf0135eb56bb410997dccea39c5ede88a0617f
ToppCellTCGA-Pancreas-Primary_Tumor-Pancreatic_Adenocarcinoma-Ductal_Adenocarcinoma-4|TCGA-Pancreas / Sample_Type by Project: Shred V9

TSHZ2 LAMA2 ANKRD6 ADAMTSL3 ADAM22 ITPR2 ZFHX4 TOR1AIP1

8.26e-07184179867164bb6bcae7322cb89b585c7aa10bce35b0ecd
ToppCellLPS-IL1RA+antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-MatrixFB_->_Myofibroblast|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PCSK5 TSHZ2 SERPINF1 LAMA2 ADAMTSL3 ADAM22 ZFHX4 PALLD

8.61e-0718517983b2dfc8f4c87be516265dbecfc251276034d0efd
ToppCell3'_v3-GI_small-bowel-Myeloid_Mac-Erythrophagocytic_macrophages|GI_small-bowel / Manually curated celltypes from each tissue

MRC1 ENOX1 SPI1 LILRB2 SERPINF1 DUSP15 EPB41L3 ADAMDEC1

8.96e-071861798a0cc925af97e47efd0c9bc17c37963e8ad4e5b35
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PCSK5 PDE7A NCKAP5 EPB41L3 TRPM3 ZNF804B ACSM2A ACSM2B

9.33e-071871798dcf6475ece5b34d9d58a0d1f51c18acedb19c119
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PCSK5 PDE7A NCKAP5 EPB41L3 TRPM3 ZNF804B ACSM2A ACSM2B

9.33e-071871798f1356273bd3587b6883295edf15cb9cdb706c057
ToppCellAdult-Immune-T_lymphocyte-D175|Adult / Lineage, Cell type, age group and donor

ACAP1 PDE7A RASGRF2 TSHZ2 SYTL2 SPOCK2 UBASH3A PBXIP1

1.09e-0619117980b84fd1dc68146d9f72422b102744d2847f5ecb2
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-Adaptive_/_Maladaptive_/_Repairing_Fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

TSHZ2 SERPINF1 LAMA2 ADAMTSL3 LPAR1 MAP3K5 ZFHX4 EEF2K

1.09e-0619117982c51850f5c559d665b8a27a12b75af9ed58dffe1
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

TSHZ2 LAMA2 ADAMTSL3 LPAR1 ZFHX4 NAV2 PLD5 PALLD

1.14e-0619217985105e4b577408b4e1a62d0a44c23c2b830ccad88
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-Adaptive_/_Maladaptive_/_Repairing_Fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

TSHZ2 SERPINF1 LAMA2 ADAMTSL3 LPAR1 ZFHX4 NAV2 PLD5

1.23e-061941798c49f72441b3557e2c3a9c4239e68c0cf0652814b
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

TSHZ2 SERPINF1 LAMA2 ADAMTSL3 LPAR1 ZFHX4 NAV2 PLD5

1.28e-0619517983c3703f092b6fc1b7333426fb5e2823bfb74bb57
ToppCellCOVID_non-vent-Lymphocytic-T_cell-CD4+_Memory_T_cell|COVID_non-vent / Disease condition, Lineage, Cell class and subclass

ACAP1 PDE7A TSHZ2 SPOCK2 UBASH3A LRIG1 HERC6 PBXIP1

1.28e-06195179822191d361af136942508f1553ff41a626ed982ad
ToppCellnucseq-Mesenchymal-Fibroblastic|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

DENND2A SERPINF1 LAMA2 ADAMTSL3 LPAR1 NAV2 MACF1 PALLD

1.33e-0619617987d8505dac15fa59935ccf592afc54b04c4c6554f
ToppCellmild-low-quality_cells|mild / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

TSHZ2 LYG2 SYTL2 LINC00299 DGKE ADAM22 MED17 RAB27B

1.38e-061971798e4331969bd911d1ebb5453f40a7057297b5389b4
ToppCellhealthy_donor-Lymphocytic-T_cell-CD4+_Naive_T_cell|healthy_donor / Disease condition, Lineage, Cell class and subclass

ACAP1 PDE7A RASGRF2 TSHZ2 VSIG1 SPOCK2 UBASH3A PBXIP1

1.38e-061971798cf72160f03105876641fa6fdc7405e339eb084c7
ToppCell5'-Airway_Nasal-Immune_Lymphocytic-Lymphocytic_T/NK|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

B3GALT2 ACAP1 PDE7A PHTF2 SPOCK2 UBASH3A PBXIP1 AGAP2

1.38e-061971798486af69d2840d351790ee41dc7438c02c615740b
ToppCellPBMC-Severe-Myeloid-Classical_Monocyte-Classical_Monocyte-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

ZNF629 ADAM22 SKOR1 DYNLT5 ZNF479 ALDH4A1 PLD5

1.40e-06137179712caa8ed7cc9e7a0f78c14ad5efe2fc28c3ce9be
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

FOXO3 TSHZ2 LAMA2 LPAR1 RGS16 NAV2 PLD5 PALLD

1.43e-061981798a860246bcea847249a78fd2e86ed8e04371060db
ToppCellLPS_IL1RA_TNF-Mesenchymal_myocytic|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

PCSK5 DENND2A SYTL2 LAMA2 ADAMTSL3 ADAM22 PALLD VCL

1.54e-062001798f599e4b051ac3dad11ad437e98dc8ea6754cca53
ToppCellCOVID-19-COVID-19_Severe-Lymphocyte-T/NK-CD4+_T_activated|COVID-19_Severe / Disease, condition lineage and cell class

ACAP1 RASGRF2 TSHZ2 VSIG1 SPOCK2 UBASH3A HERC6 PBXIP1

1.54e-062001798deeed668b129e66156b5f6abe1a07a9bf842a14d
ToppCellControl_saline-Mesenchymal_myocytic-Myofibroblastic-MatrixFB_->_Myofibroblast|Control_saline / Treatment groups by lineage, cell group, cell type

PCSK5 DENND2A TSHZ2 SERPINF1 SYTL2 ADAMTSL3 ZFHX4 PALLD

1.54e-062001798a799fc7bb83ad0524362cb5010df949741fb7bf3
ToppCellLPS_anti-TNF-Mesenchymal_myocytic|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

PCSK5 DENND2A SERPINF1 SYTL2 LAMA2 ADAMTSL3 PALLD VCL

1.54e-06200179867dcbd86fbc79fd585d0793f979e4aac100326c9
ToppCell356C-Lymphocytic-ILC-ILC-2|356C / Donor, Lineage, Cell class and subclass (all cells)

ACAP1 FBF1 VSIG1 DGKE ZNF514 PBXIP1 ACSM2B

3.18e-0615517970fd66c623cb433ceaa893bc21ba2e3b394faaf70
ToppCellChildren_(3_yrs)-Epithelial-basal_cell-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

ATP13A4 CDH26 GCM2 SERPINF1 VWDE LRIG1 WDR87

3.46e-0615717976ee2692f705bdd93ba523dffaf2f0cd921b47e28
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

FOXO6 TSHZ2 UBASH3A LPAR1 MAP3K5 ZNF10 PALLD

4.25e-06162179768c40d12689cc1b6c797e6e48173f0110f8144e4
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-kidney_interstitial_fibroblast_5|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

FOXO6 TSHZ2 UBASH3A LPAR1 MAP3K5 ZNF10 PALLD

4.25e-061621797735fa3f77b31a4189e431d05c326403c18cbbffb
ToppCell367C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_0.5|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

CDH26 ZNF486 LINC00299 THRB TRPM3 FCGR3A EEF2K

5.20e-061671797e242827999caad08b0894d88ab97bc1df41b7650
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

TSHZ2 LAMA2 LPAR1 MAP3K5 NAV2 PLD5 PALLD

5.84e-06170179703044e1436443b28dd39d5ef4fdb25c18e3a7546
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

TSHZ2 LAMA2 LPAR1 MAP3K5 NAV2 PLD5 PALLD

5.84e-061701797fa753cc8fbd04e63c9a303da4dc17ee2ce907f92
ToppCellEndothelial-Endothelial-G|Endothelial / shred on cell class and cell subclass (v4)

MRC1 DENND2A TSHZ2 FAM217A RGS16 MYO15B FAM120C

6.31e-061721797644f8e42ee8d8996f6ae50cdf874559be55509fc
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_1_/_Segment_2|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

PDE7A NCKAP5 EPB41L3 TRPM3 ZNF804B ACSM2A ACSM2B

6.55e-0617317978888434641ea554a9b62c436e87920378eef29cd
ToppCellP15-Endothelial-lymphatic_endothelial_cell|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

MRC1 TSHZ2 ANKRD6 FAM217A RGS16 ZFHX4 PLD5

7.06e-061751797a00c6fa9b33640710dd05a3799031147196f0986
ToppCellfacs-Lung-ENDOMUCIN-18m-Endothelial-Lymphatic_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MRC1 TSHZ2 ANKRD6 FAM217A RGS16 SMARCA1 PLD5

7.06e-0617517979d082ba0e350162aa6e71b668be074b12a27c7ab
ToppCellfacs-Lung-ENDOMUCIN-18m-Endothelial-endothelial_cell_of_lymphatic_vessel|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MRC1 TSHZ2 ANKRD6 FAM217A RGS16 SMARCA1 PLD5

7.06e-061751797f641f34b52aec5d047430a6f9d026e915da6c11d
ToppCellP15-Endothelial-lymphatic_endothelial_cell-endothelial_cell_of_lymphatic_vessel|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

MRC1 TSHZ2 ANKRD6 FAM217A RGS16 ZFHX4 PLD5

7.06e-06175179784d252f3e432231687613299bbea14978bb4b06b
ToppCellControl-Epithelial_alveolar-AT_1-Differentiating_AT1|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ATP13A4 SPOCK2 EPB41L3 MAP3K5 TRPM3 NAV2 PLD5

7.61e-0617717979af14a056eb6d88c6f11b09f6d4c0d3448d647d5
ToppCellfacs-Marrow-T_cells-18m-Lymphocytic-CD4-positive,_alpha-beta_T_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TSHZ2 SPOCK2 ITGAV VWDE RGS16 LRIG1 NAV2

7.89e-06178179743eda32af2e5e28a92421612d0a4c21e5427a772
ToppCellfacs-Marrow-T_cells-18m-Lymphocytic-BM_CD4_T_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TSHZ2 SPOCK2 ITGAV VWDE RGS16 LRIG1 NAV2

7.89e-061781797888add8935ef3aef9b6693c5698e9d1842e66337
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-kidney_interstitial_fibroblast_5|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

TSHZ2 LAMA2 LPAR1 ZFHX4 NAV2 PLD5 PALLD

7.89e-061781797d4ecb84e9b1f4ec49c519321156aa10f9bd34cce
ToppCellLPS-IL1RA-Epithelial_alveolar-AT_1-Differentiating_AT1|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ATP13A4 PDE7A SPOCK2 EPB41L3 TRPM3 NAV2 PLD5

8.19e-06179179704ce3673e46606f63d9c87bcba3a64c96817d812
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Degenerative_Proximal_Tubule_Epithelial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PCSK5 PDE7A EPB41L3 TRPM3 ZNF804B ACSM2A ACSM2B

8.19e-06179179778fae47ec9bff4e0159a86a281e831d7f8ee925a
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_1_/_Segment_2|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PDE7A NCKAP5 EPB41L3 TRPM3 ZNF804B ACSM2A ACSM2B

8.49e-061801797f8bdfd7bf7b3d52c659a29d8f5f80858e79da83e
ToppCell5'-Adult-LymphNode-Mesenchymal-fibroblastic-Transitional_Stromal_3_(C3+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ENOX1 SERPINF1 LAMA2 EFCAB3 ADAMTSL3 RGS16 ZFHX4

8.80e-061811797ab66a89f316b935d9ba1277426d976b1e9e39757
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L5-6_PVALB_FAM150B|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

DENND2A NXPH1 IGDCC4 TRPM3 SPOCK3 SVIL DYNLT5

8.80e-061811797af92b8b7f455210dab502ef6964f3a0162180759
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

PDE7A NCKAP5 EPB41L3 TRPM3 ZNF804B ACSM2A ACSM2B

8.80e-0618117979542c19edc9bd2cba68c01c2a8407705398e3011
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

PDE7A NCKAP5 EPB41L3 TRPM3 ZNF804B ACSM2A ACSM2B

8.80e-0618117978f04f8cac5d705dc5f6cf6f4516d6e45b0aa4ae5
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_1_/_Segment_2|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CLEC18B NCKAP5 EPB41L3 TRPM3 ZNF804B ACSM2A ACSM2B

9.45e-061831797facd6dbe0851b537d70a899ac7485714ab27d071
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-kidney_interstitial_fibroblast_5|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

TSHZ2 LAMA2 ADAMTSL3 LPAR1 NAV2 PLD5 PALLD

9.80e-061841797c5436a8e45f471b8d1301abbe9c7879204537f52
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

TSHZ2 LAMA2 ADAMTSL3 LPAR1 NAV2 PLD5 PALLD

9.80e-061841797e061e85c4bb19f49f6451ddd7a9077d7378ee365
ToppCellCOVID-19-kidney-PCT-S1/S2|kidney / Disease (COVID-19 only), tissue and cell type

PCSK5 NCKAP5 EPB41L3 TRPM3 ZNF804B ACSM2A ACSM2B

9.80e-061841797dc71f22583fc54b89b242cbb602f4bbe86f576ec
ToppCellLPS-antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-MatrixFB_->_Myofibroblast|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PCSK5 DENND2A TSHZ2 SERPINF1 ADAM22 ZFHX4 PALLD

1.01e-0518517976712512100ccef456d2e2bd201d0987986c92ac9
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_1_/_Segment_2|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

PCSK5 NCKAP5 EPB41L3 TRPM3 ZNF804B ACSM2A ACSM2B

1.05e-0518617975784d255e9ca449d375d81938d0fbbd8a7eb44f6
ToppCellLPS-IL1RA+antiTNF-Epithelial_alveolar-AT_1-Differentiating_AT1|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ATP13A4 PDE7A SPOCK2 EPB41L3 TRPM3 NAV2 PLD5

1.05e-0518617973aebe163799109ffc67e4e10ee47c2dd0886a92c
ToppCellControl-Fibroblasts-Other_FB|Control / group, cell type (main and fine annotations)

DENND2A ENOX1 TSHZ2 LAMA2 ADAMTSL3 LPAR1 PALLD

1.09e-051871797bd3739c4a52aa1ba5deffd778e113a9800f7e158
ToppCellCOVID-19-kidney-Stressed_PCT|kidney / Disease (COVID-19 only), tissue and cell type

PCSK5 NCKAP5 EPB41L3 TRPM3 ZNF804B ACSM2A ACSM2B

1.09e-051871797acd305475f3609800af0d7bc68d83ef41228080b
ToppCell3'_v3-GI_small-bowel-Myeloid_Monocytic-Nonclassical_monocytes|GI_small-bowel / Manually curated celltypes from each tissue

SPI1 LILRB2 EPB41L3 LPAR1 FCGR3A SVIL MS4A14

1.09e-051871797c20689022569640ebc4a878e3fe146b86fe9b386
ToppCellwk_15-18-Hematologic_Lymphocytic-T_&_ILC-ILC3|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

ACAP1 SYTL2 LINC00299 SPOCK2 UBASH3A PBXIP1 AGAP2

1.09e-051871797a037631a01d2cce088e6522dceeb1eee806522a1
ToppCellControl-Fibroblasts-Alveolar_FB|Control / group, cell type (main and fine annotations)

DENND2A LAMA2 ADAMTSL3 LPAR1 NAV2 MACF1 PALLD

1.09e-05187179792d468dde81125d51daf7abd4703741abe1ab91c
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

ACAP1 RASGRF2 TSHZ2 SYTL2 SPOCK2 UBASH3A PBXIP1

1.17e-0518917975a9e2ca9a9ee2dc37ab9147a902115a9f1a80169
ToppCell3'_v3-lymph-node_spleen-Myeloid_Mac-Erythrophagocytic_macrophages|lymph-node_spleen / Manually curated celltypes from each tissue

MRC1 NCKAP5 DUSP15 EPB41L3 ADAMDEC1 FCGR3A SMARCA1

1.21e-05190179796c6078619e85f630c9754aca5d6066433e22836
ToppCellT_cells-Effector_memory_CD4+_T_cells|World / Immune cells in Kidney/Urine in Lupus Nephritis

B3GALT2 ACAP1 PDE7A RASGRF2 SPOCK2 LRIG1 PBXIP1

1.21e-05190179713dc3a0aaa554f63eabac37726bd1f11b66fb3dd
ToppCellControl-T_cells-CD4+_T_cells|Control / group, cell type (main and fine annotations)

ACAP1 PDE7A RASGRF2 LINC00299 SPOCK2 UBASH3A PBXIP1

1.21e-0519017970733be5e54fe15d6d6ea51c154a95258e83f1b92
ToppCellT_cells-Effector_memory_CD4+_T_cells|T_cells / Immune cells in Kidney/Urine in Lupus Nephritis

B3GALT2 PDE7A RASGRF2 SPOCK2 RGS16 LRIG1 PBXIP1

1.21e-0519017971af91fe0ee2c924e12f4db93c793e7af475d8f80
ToppCellCOVID-19-T_cells-CD4+_T_cells|COVID-19 / group, cell type (main and fine annotations)

ACAP1 PDE7A RASGRF2 SYTL2 SPOCK2 UBASH3A PBXIP1

1.25e-0519117970646cca78e24aeb6baa9934d3c439b797c567997
ToppCellnucseq-Mesenchymal-Fibroblastic-Fibroblastic_2-AF1|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

DENND2A LAMA2 ADAMTSL3 LPAR1 NAV2 MACF1 PALLD

1.25e-0519117976688cee34beee4f151ac17fccbc9c26a9aad72e1
ToppCellnucseq-Mesenchymal-Fibroblastic-Fibroblastic_2|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

DENND2A LAMA2 ADAMTSL3 LPAR1 NAV2 MACF1 PALLD

1.29e-05192179799ce9e3c4c50cf64ebb62145f2b5420efa0db309
ToppCellMesenchymal-matrix_fibroblast_2_cell|World / Lineage, Cell type, age group and donor

DENND2A TSHZ2 SERPINF1 LAMA2 ADAMTSL3 LPAR1 IGDCC4

1.29e-051921797a769158c49d2b208c4224d85e7ae68c85cc372ed
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

TSHZ2 LAMA2 LPAR1 ZFHX4 PLD5 PALLD VCL

1.34e-051931797c8c21eee8c6c086dc2faf416669cd4a002870fbe
ToppCellT_cells-Central_memory_CD4+_T_cells|World / Immune cells in Kidney/Urine in Lupus Nephritis

ACAP1 PDE7A RASGRF2 VSIG1 SPOCK2 UBASH3A PBXIP1

1.34e-051931797725326d7e3604736b607c19f4069c81cb4f2d20c
ToppCellAdult-Immune-T_lymphocyte|Adult / Lineage, Cell type, age group and donor

ACAP1 RASGRF2 SYTL2 LINC00299 SPOCK2 UBASH3A PBXIP1

1.34e-05193179726df0c4c8a2355dd5503fadd07e368eb9a2bf06a
ToppCellChildren_(3_yrs)-Mesenchymal-matrix_fibroblast_2_cell|Children_(3_yrs) / Lineage, Cell type, age group and donor

DENND2A TSHZ2 SERPINF1 LAMA2 ADAMTSL3 LPAR1 IGDCC4

1.34e-0519317979ab47b360bee1d4f1092c2269e58acebe9584021
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

TSHZ2 LAMA2 LPAR1 ZFHX4 PLD5 PALLD VCL

1.34e-0519317975b602b1702283184bd3943c2a6f2290b7c37e407
ToppCellBAL-Control-Lymphocyte-T/NK-CD4+_T-CD4+_T_1-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

ACAP1 TSHZ2 SYTL2 SPOCK2 UBASH3A RGS16 PBXIP1

1.38e-051941797c30b6d1fd5fabd99e25857f7486d6dc9c054f552
ToppCelldroplet-Pancreas-Exocrine-21m-Mesenchymal-pancreatic_stellate_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PCSK5 SERPINF1 SYTL2 LAMA2 LPAR1 CENPP PALLD

1.38e-051941797775600880bb77781de48085d8744c1030223de1f
ToppCelldroplet-Pancreas-Exocrine-21m-Mesenchymal|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PCSK5 SERPINF1 SYTL2 LAMA2 LPAR1 CENPP PALLD

1.38e-05194179704ecb609d233a4b12e275c604810937830363e17
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

TSHZ2 LAMA2 LPAR1 MAP3K5 PLD5 PALLD VCL

1.38e-05194179790efdbd7f1c85fd7fd622b10340250b1d8fc1197
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

TSHZ2 LAMA2 LPAR1 MAP3K5 PLD5 PALLD VCL

1.38e-051941797df82cce5ebeb73740b02cf816c6df82253cfd566
ToppCellLA-02._Fibroblast_II|LA / Chamber and Cluster_Paper

FOXO3 PCSK5 TSHZ2 SERPINF1 LAMA2 LPAR1 NAV2

1.38e-051941797234d1494c114cce77c619708bbcd8d5ce805f19b
ToppCellAdult-Immune-T_lymphocyte-D231|Adult / Lineage, Cell type, age group and donor

ACAP1 RASGRF2 SYTL2 PHTF2 LINC00299 SPOCK2 UBASH3A

1.38e-0519417975c1dca33f382f37a7deb23e573578343c3b54986
ToppCellChildren_(3_yrs)-Immune-T_lymphocyte-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

ACAP1 PDE7A RASGRF2 SYTL2 PHTF2 SPOCK2 UBASH3A

1.38e-0519417973d6f2d190dd50804afea299957cc44c2bb756134
ToppCellBAL-Control-Lymphocyte-T/NK-CD4+_T-CD4+_T_1|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

ACAP1 TSHZ2 SYTL2 SPOCK2 UBASH3A RGS16 PBXIP1

1.38e-051941797749cc39cbe5d68372fc43f7dbdbe5004cd01ace8
ToppCellBAL-Control-Lymphocyte-T/NK-CD4+_T|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

ACAP1 TSHZ2 SYTL2 SPOCK2 UBASH3A RGS16 PBXIP1

1.38e-051941797a7f11ac46965b3fc21c9d04870ce0bd2b3868cec
ToppCellControl-T/NK-CD4+_T_1|Control / Disease group,lineage and cell class （2021.01.30）

ACAP1 TSHZ2 SYTL2 SPOCK2 UBASH3A RGS16 PBXIP1

1.38e-051941797908cc9a3b0b99aea28a24bbd27667c824743e967
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

TSHZ2 LAMA2 LPAR1 ZFHX4 NAV2 PLD5 PALLD

1.38e-051941797e03ba6caed59fa64d4d9b042593469d4a6a3dc10
ToppCellPBMC-Control-Lymphocyte-T/NK-CD8+_T-MAIT|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

B3GALT2 ACAP1 PDE7A RASGRF2 SYTL2 SPOCK2 PBXIP1

1.43e-051951797c7b54b210cc2c8ddaefebfba74381adb2ca698b8
ToppCellCOVID_non-vent-Lymphocytic-T_cell|COVID_non-vent / Disease condition, Lineage, Cell class and subclass

ACAP1 RASGRF2 TSHZ2 SPOCK2 UBASH3A MACF1 PBXIP1

1.43e-0519517974bdedd924564a260841a9153604026b57487c83d
ToppCellCOVID-19_Severe-Lymphoid_T/NK-gd_T|COVID-19_Severe / Disease group, lineage and cell class

SYTL2 LAMA2 TRGV11 SPOCK2 FCGR3A UHMK1 MACF1

1.43e-0519517979990440bda7fac5d00ef80444fab07459be625e1
ToppCellPBMC-Control-Lymphocyte-T/NK-CD8+_T-MAIT-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

B3GALT2 ACAP1 PDE7A RASGRF2 SYTL2 SPOCK2 PBXIP1

1.43e-051951797a8fd42ff6c2bd80d0e3f20fe3bbf7d113b399df1
ToppCellPBMC-Severe-Lymphocyte-T/NK-Other_T-gd_T|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

SYTL2 LAMA2 TRGV11 SPOCK2 FCGR3A UHMK1 MACF1

1.48e-051961797418e8e0a51c5cb60e3b903e7d2d800dc8b9f3d5c
Diseasethyroid nodule

EPB41L3 TRPM3

3.46e-0521742EFO_1001436
DiseaseX-21319 measurement

ACSM2A ACSM2B

3.46e-0521742EFO_0800807
DiseaseX-11478 measurement

ACSM2A ACSM2B

1.03e-0431742EFO_0021242
Diseasepigment epithelium-derived factor measurement

SERPINF1 SMYD4

1.03e-0431742EFO_0021847
DiseaseHyperhidrosis

PLB1 LONP2

1.03e-0431742HP_0000975
Disease3-hydroxyhexanoate measurement

ACSM2A ACSM2B

3.42e-0451742EFO_0800378
Diseasetotal blood protein measurement

TRPC4AP DNAJC13 ILF3 SPI1 PHTF2 DGKE MAP3K5 MACF1 ASCC3 SERPINA5

3.54e-0444917410EFO_0004536
Diseaseindoleacetoylcarnitine measurement

ACSM2A ACSM2B

5.11e-0461742EFO_0800106
DiseaseCholangitis, Sclerosing

UBASH3A ABCB4

5.11e-0461742C0008313
DiseaseAlzheimer disease, survival time

NCKAP5 ALDH4A1

9.46e-0481742EFO_0000714, MONDO_0004975
DiseasePrimary sclerosing cholangitis

UBASH3A ABCB4

9.46e-0481742C0566602
Diseaseadvanced glycation end-product measurement, type 2 diabetes mellitus

FBXO33 PALLD

9.46e-0481742EFO_0007819, MONDO_0005148
DiseaseX-17676 measurement

ALDH4A1 ACSM2B

9.46e-0481742EFO_0800785
Diseasesmoking behavior

FOXO3 FOXO6 RASGRF2 LAMA2 SPOCK2 ITIH4 NAV2 ASCC3

9.88e-043411748EFO_0004318
Diseaseverbal-numerical reasoning measurement

FOXO3 FOXO6 FOXN3 TNRC6A ARMH3

1.10e-031311745EFO_0008394
Diseaseemotional symptom measurement

ZNF254 UHMK1

1.21e-0391742EFO_0007803
Diseasepost-operative acute kidney injury

CDH26 RCC2

1.21e-0391742EFO_0009955
Diseasegamma-glutamylisoleucine measurement

LILRB2 LAMA2

1.21e-0391742EFO_0021139
Diseaseplexin-B2 measurement

MRC1 FCGR3A

1.21e-0391742EFO_0021867
DiseaseVertigo

MALRD1 SPOCK3 SVIL ZNF804B OTOG

1.43e-031391745HP_0002321
Diseaseage at onset, multiple sclerosis

PCSK5 NCKAP5

1.51e-03101742EFO_0004847, MONDO_0005301
Diseasebipolar I disorder

MAPK8IP1 ILF3 BABAM2 ITIH4 SLC25A17

1.53e-031411745EFO_0009963
Diseasesquamous cell lung carcinoma, family history of lung cancer

SPI1 CENPP THRB PLD5

1.63e-03851744EFO_0000708, EFO_0006953
DiseaseMalignant neoplasm of breast

ACAP1 GFRAL RASGRF2 LAMA2 MRPL13 DGKE EPB41L3 FSCB LPAR1 PIK3R4 ARFGAP3 FAM217B MACF1 TOR1AIP1 AGAP2

1.81e-03107417415C0006142
Diseasesalicylate measurement

PLD5 ACSM2A

1.84e-03111742EFO_0021161
Diseasecreatinine measurement

DENND5B FOXO3 DNAJC13 FOXO6 PDE7A LAMA2 PHTF2 MRPL13 EPB41L3 BABAM2 LRIG1 SVIL ASCC3 ACSM2B

2.40e-0399517414EFO_0004518
DiseaseParkinson's disease (implicated_via_orthology)

FOXO3 ATP13A4 FOXO6 TOR1A FOXO4

2.44e-031571745DOID:14330 (implicated_via_orthology)
DiseaseInfantile Severe Myoclonic Epilepsy

GABRG2 TNRC6A

2.58e-03131742C0751122
Diseaselow affinity immunoglobulin gamma Fc region receptor III-B measurement

FCGR3A MS4A14

3.00e-03141742EFO_0008212
Diseasehepatocellular carcinoma (implicated_via_orthology)

POLG LPAR1 ABCB4

3.04e-03491743DOID:684 (implicated_via_orthology)
Diseasecolorectal cancer

DENND5B FOXO6 ERAP1 SPOCK2 LPAR1 THRB LRIG1 CAPRIN2 SKOR1 MACF1

3.24e-0360417410MONDO_0005575
Diseaserheumatoid arthritis, anti-citrullinated protein antibody seropositivity, rheumatoid factor seropositivity measurement

ZNF629 FAM76B UBASH3A KSR1 FCGR3A

3.43e-031701745EFO_0000685, EFO_0007791, EFO_0007837
Diseasesusceptibility to rubella infection measurement

FAM76B THRB TRPM3

3.60e-03521743EFO_0008418
Diseasepulse pressure measurement

FOXO3 PHTF2 FAM76B CLEC18C TSC22D2 ADAMTSL3 PIK3R4 CENPP MALRD1 ZFHX4 LRIG1 ARVCF TRPM3 TNRC6A ARMH3 PALLD VCL

3.69e-03139217417EFO_0005763
Diseaseureidopropionic acid measurement

SPOCK2 OTOG

3.93e-03161742EFO_0010542
Diseasecentral nervous system disease (implicated_via_orthology)

SMARCA5 SMARCA1

3.93e-03161742DOID:331 (implicated_via_orthology)
Diseaseelectrocardiography

LINC00299 FOXN3 THRB LRIG1 TRPM3 SVIL NAV2 PALLD VCL

4.37e-035301749EFO_0004327
Diseasecopine-1 measurement

TRPC4AP CNBD2

4.44e-03171742EFO_0008102
Diseaseisoleucine measurement

LILRB2 LAMA2 ZNF804B

4.44e-03561743EFO_0009793
Diseasecognitive function measurement, self reported educational attainment

FOXO3 FOXO6 SPI1 WRN TNRC6A FBXO33 ARMH3

5.27e-033551747EFO_0004784, EFO_0008354
Diseasemacula measurement

FOXO3 FAM76B TSC22D2 TNRC6A NAV2

5.37e-031891745EFO_0008375

Protein segments in the cluster

PeptideGeneStartEntry
DQAWGKHRRQNSLKS

LINC00299

61

Q6ZSB3
ASQATRKHGTDLWLD

ARFGAP3

121

Q9NP61
LLKNKDGWNSFHIAS

ANKRD16

131

Q6P6B7
KDGWTKARFQSAAAT

ARVCF

841

O00192
HKGAKSESAESLRQW

APOL4

316

Q9BPW4
WLSSAKIHQKFGSGL

ATP13A4

156

Q4VNC1
WLNFKKLLNEASTTH

ACSM2A

191

Q08AH3
NAKGRAAHSWKKRGS

DYNLT5

6

Q8N7M0
KKRGSISSLSNHEFW

DYNLT5

16

Q8N7M0
KKRSNGLSHSWSERI

ADAM22

801

Q9P0K1
GLRWKHTSSLKVANE

ALDH4A1

21

P30038
SFLLKRSGNSLNKEW

AGAP2

681

Q99490
AGQWKEAASKVTHAL

ARMH3

576

Q5T2E6
HLFKRASNAFKTWSR

ACAP1

271

Q15027
AIHQFNLEGWKSSKD

CENPP

41

Q6IPU0
SWHGFSQSAKLLIKA

ANKRD6

116

Q9Y2G4
SEGRSHSKRKISWAQ

IGDCC4

1051

Q8TDY8
ALTTWQNKTKAHIRF

ITIH4

201

Q14624
HTLVLDSQKRVFSWG

RCC2

341

Q9P258
WESENQNKGVKLSHR

RAB18

176

Q9NP72
SSGKAFKVHLQLWDT

RAB27B

61

O00194
AGQWNSLFRFKHLAT

ITPR2

296

Q14571
LSWTTHAKERAFKQQ

MFN1

631

Q8IWA4
RKFIWTNHKFNVTGT

NDUFA12

106

Q9UI09
SAHLAISWLRSNAKK

LONP2

696

Q86WA8
SNNSIARIHRKGWSF

LRIG1

291

Q96JA1
HRNTSSIASWFGLKK

NCKAP5L

911

Q9HCH0
VSSELQQTWTKRKHG

FSCB

51

Q5H9T9
NSRGNAWSRKHKTLS

LIPM

131

Q5VYY2
SLGKKHSWQDRVSRS

MAPK8IP1

181

Q9UQF2
KAWDHFTKAQRKNIS

ENOX2

346

Q16206
RSGKHLATEWNTVSK

LPAR1

36

Q92633
NDEHWKALSRKSTSF

FBXO33

356

Q7Z6M2
NWNKLVQKFELGSSS

ERAP1

856

Q9NZ08
ANDWKTNAAGFKVSH

PCSK5

426

Q92824
GKHGFSDNQKLWERN

PCNP

151

Q8WW12
FNSLKALWVKGQHST

SLC25A17

86

O43808
SSAGWKNSIRHNLSL

FOXO4

146

P98177
GHFWKSADINSSKVV

KSR1

891

Q8IVT5
VDKHWNGSGSLLLNK

LRRC36

536

Q1X8D7
LNKASWKGLQREQSS

PDE7A

446

Q13946
SESSRKSWNQKHFAL

CYLC1

21

P35663
SWNKVQHSKNSSGKR

FAM217B

6

Q9NTX9
KSDAKWREVSHTFSN

FBXO44

201

Q9H4M3
SNSSAGWKNSIRHNL

FOXO6

131

A8MYZ6
LALSKDSQVFSWGKN

HERC6

141

Q8IVU3
SFQRSLWIAAKQGKH

POLG

306

P54098
QKFLSQWKISHTTGI

HERVK_113

721

P63132
KFTHNQLTRKLWQSG

PDZD3

276

Q86UT5
QSWRQFHTFLLTKAG

LILRB2

346

Q8N423
RQGKHWTSTQRKADF

LILRB2

486

Q8N423
EEQGLWKQSHKSSAT

FAM76B

196

Q5HYJ3
NHNDGKWKSFTLSRI

LAMA2

2416

P24043
KSDVLQDNKWSHLRG

MED17

606

Q9NVC6
QKFLSQWKISHTTGI

ERVK-7

721

P63135
QKFLSQWKISHTTGI

ERVK-6

721

Q9BXR3
RHWLSDVKDKNSVFS

MACF1

1201

Q9UPN3
NAKHLAEASQKLASW

MGAT4D

216

A6NG13
NGWKSRLFRHSTQKN

ABCB4

656

P21439
FWKKENESLTHSTDR

PALLD

1266

Q8WX93
FSFSKEQRSGWHKGQ

MYO15B

1486

Q96JP2
SVALLKSQDHGRSWA

NTN3

131

O00634
QKFLSQWKISHTTGI

ERVK-18

721

Q9QC07
GKIIRFSESQWSHAK

MALRD1

581

Q5VYJ5
KSETNHSSLRNIWKE

B3GALT2

71

O43825
QQLVHKKDSGFWRDF

CSGALNACT2

416

Q8N6G5
EDWLSHALSRKKSQG

FBF1

421

Q8TES7
KKNNWTGEFSARFLL

BABAM2

161

Q9NXR7
WTGRQKSSADHRKSY

DENND2A

321

Q9ULE3
DKFKWNLTTRSHHGF

GFRAL

111

Q6UXV0
AFSHQNLKLKWGEGT

FNDC3A

961

Q9Y2H6
TGWKNSVRHNLSLNK

FOXN3

156

O00409
GWASSQKGARHRTSK

DUSP15

136

Q9H1R2
HQWFGASVRSKQDKI

ITGAV

121

P06756
KAKWETSFNHKGTQE

SERPINA5

206

P05154
HALKLSWNGKNLTTN

FAM120C

276

Q9NX05
RHAKWFQARANGLKS

ILF3

211

Q12906
FFRNSKKADAHWITT

GABRG2

151

P18507
KQGKSALWSHLIQFQ

DENND5B

796

Q6ZUT9
LSSFEETNKKQRWLH

CEP162

676

Q5TB80
ETNKKQRWLHFGEAA

CEP162

681

Q5TB80
KQESFKSWEASGKHQ

CAPRIN2

416

Q6IMN6
GQDHARSNLIWNFKT

DNAJC13

766

O75165
KSSKRHSLDQQSKGW

MS4A14

511

Q96JA4
WSVAQHLKGGLSAFK

LYG2

166

Q86SG7
TSAWRAKFNILHGNE

CDH26

306

Q8IXH8
KLSNFLHAQQWKGAS

EEF2K

151

O00418
RKSKHGWRDTDLFSQ

DGKE

56

P52429
LHNLALSKSDNWKVT

FAM217A

261

Q8IXS0
TNIRSSTRDWKDHKF

FCGR3A

231

P08637
DFSKVFHGNESLWKN

DHRS2

221

Q13268
FHKRDWKTQAANIKS

EFCAB3

281

Q8N7B9
STRQKAWDHFSKAQR

ENOX1

356

Q8TC92
IKKQVRSGAWHFSFN

EPB41L3

171

Q9Y2J2
KTQQEKRHSWFKASG

PARP6

151

Q2NL67
QNKLGDTALHAAAWK

OSTF1

136

Q92882
AAGKTTWAIKHAASN

HNRNPUL1

431

Q9BUJ2
DHRKSGKLSVSQWAF

PPEF1

496

O14829
LAKWQGRDTFQQHAS

OTOG

1331

Q6ZRI0
QINSKSALTWHQARK

MRC1

231

P22897
SQSKHLKARTGGSQW

FAM83G

791

A6ND36
KKGIHEWNFSASSVR

MAP3K5

596

Q99683
GWKNSVRHNLSLNKC

FOXN4

236

Q96NZ1
NSSAGWKNSIRHNLS

FOXO3

201

O43524
TQKLNLSIWHRDTFK

SYTL2

711

Q9HCH5
NFNSWRRHLKLSDKS

SKOR1

241

P84550
WRKQLSNSAQGLHKS

UTY

581

O14607
WHAAFFLSGSKKAKN

PHTF2

251

Q8N3S3
ALGDWQKSATHLQRS

SMYD4

711

Q8IYR2
KLLTQGFTNWTKRDF

SMARCA1

851

P28370
NNLFDKLIWRKHSAS

TRPC4AP

421

Q8TEL6
KGRLQSSFWIVDKQH

PLD5

216

Q8N7P1
RKIAFQLAKHLWNGT

SVIL

1616

O95425
QAFHLNTLKESKSLW

TSC22D2

661

O75157
SSYTWHDGKNLRKRQ

NCKAP5

351

O14513
HDGKNLRKRQSSQNW

NCKAP5

356

O14513
WGDFHSNIKTVKLNL

NXPH1

121

P58417
RGFLSKKTAEASRWH

RASGRF2

26

O14827
SSDEKKAQRHLSGWA

GCM2

51

O75603
WVNELRSSFKQAFGK

NAV2

1831

Q8IVL1
LGRLKSHQFFQSTWD

SMIM22

16

K7EJ46
KGRNWLHKANTESQS

WRN

1046

Q14191
WVDKDKGTFQFSSKH

SPI1

191

P17947
LKKVNWNLQHGISSF

PLB1

1291

Q6P1J6
RISNGNKIWTLKFSH

ABHD5

56

Q8WTS1
TFDNFLRWHSSNLGK

ADAMDEC1

286

O15204
WLNFKKLLNEASTTH

ACSM2B

191

Q68CK6
SELHAAKTKQAWNFL

ASCC3

2016

Q8N3C0
HLKKAWGLQGTSFSR

CNBD2

351

Q96M20
KTAKDSFRWATGEHQ

CLEC18A

376

A5D8T8
KTAKDSFRWATGEHQ

CLEC18B

376

Q6UXF7
KTAKDSFRWATGEHQ

CLEC18C

376

Q8NCF0
LRSSSNAWTLKHDLK

PIK3R4

1126

Q99570
ATKNSVGFHIAWSRL

VWDE

216

Q8N2E2
TFRNLTSIGKKWSDQ

ZNF700

56

Q9H0M5
GQSFRSKSILNRHQW

ZNF343

331

Q6P1L6
SGLSQKVIKHWFRNT

ZFHX4

2121

Q86UP3
KAFRWSTSLNEHKNI

ZNF595

291

Q8IYB9
GKAFIWSASLNEHKN

ZNF595

486

Q8IYB9
NSSENKLKEASRAHW

ZNF804B

596

A4D1E1
VNKWTLKGIHNFRAS

WDR48

321

Q8TAF3
SREQLSIQWSFFHKK

VSIG1

51

Q86XK7
NNKNSGFWHSSLIDR

TOR1A

246

O14656
LWKRSQTFLEKHLNS

TOR1AIP1

386

Q5JTV8
SWRAQHFSKGLDLST

TEP1

156

Q99973
HQKSHFQNSREWSGK

PBXIP1

461

Q96AQ6
AHFKGQWVTKFDSRK

SERPINF1

211

P36955
SRNDIQSEKWSISKH

TRPM3

116

Q9HCF6
HKSATTLSRDYKWNG

ZNF514

141

Q96K75
DKAFKWSSSLANHKS

ZNF679

386

Q8IYX0
SSKDRSLWNLHQGKQ

SOGA1

1216

O94964
ATNAQGSHWKQKRKF

THRB

231

P10828
QKFLSQWKISHTTGI

ERVK-10

721

P10266
QSLHREATKWSSKGN

VCL

971

P18206
QKFLSQWKISHTTGI

ERVK-8

721

P63133
QKFLSQWKISHTTGI

ERVK-11

721

Q9UQG0
KFEWGSKHSKENRNF

RGS16

41

O15492
SFLSWGTNKNRQKSA

RHPN2P1

536

A8MT19
STLHKRKGRQSNWNP

TSHZ2

836

Q9NRE2
NTRHIAFSGNKWEQK

MRPL13

61

Q9BYD1
WFKALHESGSQNKKT

SPOCK3

216

Q9BQ16
CGKAFSWSANLTRHK

ZNF479

246

Q96JC4
GKAFSWSSNLTRHKR

ZNF479

331

Q96JC4
ANKSAHISWKASIQG

TRGV11

31

A0A075B6L2
INRVGKVWSELFHSS

WDR62

391

O43379
GKFFSWRSNLTRHQL

ZNF10

271

P21506
GKAFIWSSNLTEHKK

ZNF726

431

A6NNF4
HSFSGSQQKWKDFEL

ZZEF1

2756

O43149
WSRQGKAGKTHKFSA

SYCN

91

Q0VAF6
WVDHTGAASQKKAFR

TRIP4

391

Q15650
GKSFSWSSSLDKHQR

ZNF18

526

P17022
RGFTWKSNLFTHQRT

ZNF875

336

P10072
GRESFATHGTSNWKK

ZMYM1

491

Q5SVZ6
ARRTHATQKNTFGWI

SLC30A1

61

Q9Y6M5
GKSFSQWSKLLRHQR

ZNF629

156

Q9UEG4
KLLTQGFTNWNKRDF

SMARCA5

836

O60264
SSSGHYVSWVKRKQD

USP14

431

P54578
KAFNWSSDLNKHKRI

ZNF486

441

Q96H40
GKAFRWNASFIQHQK

ZNF619

446

Q8N2I2
RLWKFHDFLSSGSQN

WDR87

541

Q6ZQQ6
TFNWSSILTNNKKIH

ZNF726P1

26

Q15940
LKHTVRSQEWKANSS

UHMK1

241

Q8TAS1
SRNNHWGEANKKSSS

TNRC6A

861

Q8NDV7
QHWIGFLSLKSVERS

TYRO3

96

Q06418
GKTFWEKSNLTQHQR

ZNF248

386

Q8NDW4
GKTFNWSSTLTNHRK

ZNF254

216

O75437
KWEKFGKAFNRSSHL

ZNF254

631

O75437
HGSIEANFRAWKTKF

TYW1B

176

Q6NUM6
SSISQYSGKIKHWNR

SPOCK2

46

Q92563
KSFSLKANLLRHQWT

ZNF337

551

Q9Y3M9
VKTLTHGANAAFNWR

UBASH3A

641

P57075
KAFSWGSSLVKHERV

ZNF283

466

Q8N7M2
NWKRKNTHDGLAESS

PP2D1

331

A8MPX8
SAGSTNSWELKNKQF

ADAMTSL3

1066

P82987
VNEHWAFGKNERSLK

GLYATL2

176

Q8WU03
GNSRGNTWSRKHLKL

LIPK

116

Q5VXJ0
KRHGSWKIQLNATSV

GRIN1

51

Q05586