Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionubiquitin-like protein ligase activity

MIB2 NHLRC3 RFPL4A ZZEF1 ATG3 TRIM17 RFPL4AL1

2.80e-05398457GO:0061659
GeneOntologyMolecularFunctioncalcium-induced calcium release activity

RYR2 PKD2

7.41e-056452GO:0048763
GeneOntologyMolecularFunctionubiquitin-like protein transferase activity

MIB2 NHLRC3 RFPL4A ZZEF1 ATG3 TRIM17 RFPL4AL1

1.36e-04512457GO:0019787
GeneOntologyMolecularFunctionaminoacyltransferase activity

MIB2 NHLRC3 RFPL4A ZZEF1 ATG3 TRIM17 RFPL4AL1

1.73e-04532457GO:0016755
GeneOntologyMolecularFunctionheparan sulfate binding

DMBT1 FURIN

1.77e-049452GO:1904399
GeneOntologyMolecularFunctionendopeptidase activity

PLAT TMPRSS15 CNTNAP5 TPP1 CTSZ FURIN

3.85e-04430456GO:0004175
GeneOntologyMolecularFunctionpeptidase activity

PLAT TMPRSS15 CNTNAP5 XPNPEP2 TPP1 CTSZ FURIN

6.01e-04654457GO:0008233
GeneOntologyMolecularFunctionintracellularly gated calcium channel activity

RYR2 PKD2

7.43e-0418452GO:0015278
GeneOntologyMolecularFunctionserine-type endopeptidase activity

PLAT TMPRSS15 TPP1 FURIN

8.72e-04190454GO:0004252
GeneOntologyMolecularFunctionserine-type peptidase activity

PLAT TMPRSS15 TPP1 FURIN

1.20e-03207454GO:0008236
GeneOntologyMolecularFunctionserine hydrolase activity

PLAT TMPRSS15 TPP1 FURIN

1.31e-03212454GO:0017171
GeneOntologyMolecularFunctionubiquitin protein ligase activity

MIB2 NHLRC3 RFPL4A TRIM17 RFPL4AL1

1.45e-03372455GO:0061630
GeneOntologyMolecularFunctionacyltransferase activity

MIB2 NHLRC3 RFPL4A ZZEF1 ATG3 TRIM17 RFPL4AL1

1.62e-03775457GO:0016746
GeneOntologyMolecularFunctionexopeptidase activity

XPNPEP2 TPP1 CTSZ

1.95e-03110453GO:0008238
GeneOntologyMolecularFunctionligand-gated calcium channel activity

RYR2 PKD2

2.22e-0331452GO:0099604
GeneOntologyMolecularFunctionintracellularly ligand-gated monoatomic ion channel activity

RYR2 PKD2

2.51e-0333452GO:0005217
GeneOntologyMolecularFunctionmolecular adaptor activity

FSCN2 PKP2 FCRL2 CASP8AP2 ZZEF1 SPSB1 DLGAP4 TRIM17 HIRA

2.86e-031356459GO:0060090
GeneOntologyMolecularFunctionlipase activity

PLD3 PNLIP ABHD12

3.71e-03138453GO:0016298
GeneOntologyBiologicalProcessmaintenance of animal organ identity

PKP2 USH2A

4.43e-055442GO:0048496
GeneOntologyBiologicalProcessnegative regulation of protein processing

PLAT CTSZ FURIN

6.16e-0536443GO:0010955
GeneOntologyBiologicalProcessnegative regulation of protein maturation

PLAT CTSZ FURIN

6.16e-0536443GO:1903318
GeneOntologyBiologicalProcessnegative regulation of plasminogen activation

PLAT CTSZ

1.24e-048442GO:0010757
GeneOntologyBiologicalProcessregulation of viral entry into host cell

RFPL4A FURIN RFPL4AL1

2.20e-0455443GO:0046596
GeneOntologyBiologicalProcessprotein ubiquitination

MIB2 NHLRC3 RFPL4A ZZEF1 ATG3 SPSB1 TRIM17 RFPL4AL1

2.78e-04811448GO:0016567
GeneOntologyBiologicalProcessregulation of ventricular cardiac muscle cell action potential

PKP2 RYR2

2.90e-0412442GO:0098911
GeneOntologyBiologicalProcessmodulation by symbiont of entry into host

RFPL4A FURIN RFPL4AL1

3.14e-0462443GO:0052372
GeneOntologyBiologicalProcesszymogen activation

PLAT CTSZ FURIN

3.61e-0465443GO:0031638
DomainConA-like_dom

CNTNAP4 TMPRSS15 CNTNAP5 RFPL4A USH2A SPSB1 RYR2 TRIM17 RFPL4AL1

1.77e-09219449IPR013320
DomainSPRY

RFPL4A SPSB1 RYR2 TRIM17 RFPL4AL1

1.84e-0687445SM00449
DomainSPRY

RFPL4A SPSB1 RYR2 TRIM17 RFPL4AL1

2.70e-0694445PF00622
DomainSPRY_dom

RFPL4A SPSB1 RYR2 TRIM17 RFPL4AL1

2.70e-0694445IPR003877
DomainB30.2/SPRY

RFPL4A SPSB1 RYR2 TRIM17 RFPL4AL1

2.84e-0695445IPR001870
DomainB302_SPRY

RFPL4A SPSB1 RYR2 TRIM17 RFPL4AL1

2.84e-0695445PS50188
Domain-

TMPRSS15 DMBT1 ZZEF1 LRP10

6.68e-06524442.60.120.290
DomainCUB_dom

TMPRSS15 DMBT1 ZZEF1 LRP10

9.66e-0657444IPR000859
Domain-

CNTNAP4 CNTNAP5 ZZEF1 FURIN

2.59e-05734442.60.120.260
DomainRDM

RFPL4A RFPL4AL1

5.40e-055442PF11002
DomainRDM_domain_RFPL

RFPL4A RFPL4AL1

5.40e-055442IPR022723
DomainGalactose-bd-like

CNTNAP4 CNTNAP5 ZZEF1 FURIN

7.00e-0594444IPR008979
DomainLAM_G_DOMAIN

CNTNAP4 CNTNAP5 USH2A

9.71e-0538443PS50025
DomainLaminin_G_2

CNTNAP4 CNTNAP5 USH2A

1.13e-0440443PF02210
DomainLamG

CNTNAP4 CNTNAP5 USH2A

1.51e-0444443SM00282
DomainPRY

RFPL4A TRIM17 RFPL4AL1

1.96e-0448443SM00589
DomainPRY

RFPL4A TRIM17 RFPL4AL1

1.96e-0448443IPR006574
DomainCUB

TMPRSS15 DMBT1 LRP10

2.08e-0449443PF00431
DomainCUB

TMPRSS15 DMBT1 LRP10

2.21e-0450443SM00042
DomainCUB

TMPRSS15 DMBT1 LRP10

2.63e-0453443PS01180
Domain-

TPP1 FURIN

2.94e-04114423.40.50.200
DomainPeptidase_S8/S53_dom

TPP1 FURIN

2.94e-0411442IPR000209
DomainPeptidase_S8

TPP1 FURIN

2.94e-0411442PF00082
DomainLaminin_G

CNTNAP4 CNTNAP5 USH2A

3.44e-0458443IPR001791
DomainButyrophylin

RFPL4A TRIM17 RFPL4AL1

5.98e-0470443IPR003879
DomainPropept_inh

TPP1 FURIN

7.21e-0417442IPR009020
DomainZZ

MIB2 ZZEF1

8.10e-0418442PF00569
DomainZF_ZZ_2

MIB2 ZZEF1

8.10e-0418442PS50135
DomainZF_ZZ_1

MIB2 ZZEF1

8.10e-0418442PS01357
DomainZnf_ZZ

MIB2 ZZEF1

9.04e-0419442IPR000433
DomainZnF_ZZ

MIB2 ZZEF1

9.04e-0419442SM00291
DomainFA58C

CNTNAP4 CNTNAP5

1.11e-0321442SM00231
DomainSRCR

TMPRSS15 DMBT1

1.11e-0321442PF00530
DomainFA58C_3

CNTNAP4 CNTNAP5

1.11e-0321442PS50022
DomainFA58C_1

CNTNAP4 CNTNAP5

1.11e-0321442PS01285
DomainFA58C_2

CNTNAP4 CNTNAP5

1.11e-0321442PS01286
Domain-

NEK9 TECPR1

1.22e-03224422.130.10.30
DomainRCC1/BLIP-II

NEK9 TECPR1

1.33e-0323442IPR009091
DomainF5_F8_type_C

CNTNAP4 CNTNAP5

1.45e-0324442PF00754
DomainFA58C

CNTNAP4 CNTNAP5

1.45e-0324442IPR000421
Domain-

CNTNAP4 CNTNAP5 USH2A

1.45e-03954432.60.120.200
DomainSR

TMPRSS15 DMBT1

1.57e-0325442SM00202
Domain-

TMPRSS15 DMBT1

1.57e-03254423.10.250.10
DomainSRCR_1

TMPRSS15 DMBT1

1.70e-0326442PS00420
DomainSRCR_2

TMPRSS15 DMBT1

1.70e-0326442PS50287
DomainSRCR-like_dom

TMPRSS15 DMBT1

1.70e-0326442IPR017448
DomainSRCR

TMPRSS15 DMBT1

1.83e-0327442IPR001190
DomainFIBRINOGEN_C_1

CNTNAP4 CNTNAP5

2.57e-0332442PS00514
DomainFibrinogen_a/b/g_C_dom

CNTNAP4 CNTNAP5

2.57e-0332442IPR002181
DomainFIBRINOGEN_C_2

CNTNAP4 CNTNAP5

2.57e-0332442PS51406
Domain-

CES3 PNLIP ABHD12

2.76e-031194433.40.50.1820
DomainAB_hydrolase

CES3 PNLIP ABHD12

2.76e-03119443IPR029058
DomainEGF_1

CNTNAP4 PLAT CNTNAP5 USH2A

3.00e-03255444PS00022
DomainLDLR_class-A_CS

TMPRSS15 LRP10

4.00e-0340442IPR023415
DomainPRY

RFPL4A RFPL4AL1

4.40e-0342442PF13765
DomainLdl_recept_a

TMPRSS15 LRP10

5.04e-0345442PF00057
DomainZF_RING_2

MIB2 RFPL4A TRIM17 RFPL4AL1

5.22e-03298444PS50089
Domain-

TMPRSS15 LRP10

5.26e-03464424.10.400.10
DomainLDLRA_1

TMPRSS15 LRP10

5.71e-0348442PS01209
DomainLDLRA_2

TMPRSS15 LRP10

5.95e-0349442PS50068
DomainLDrepeatLR_classA_rpt

TMPRSS15 LRP10

5.95e-0349442IPR002172
DomainLDLa

TMPRSS15 LRP10

5.95e-0349442SM00192
Pubmed

Rank-based genome-wide analysis reveals the association of ryanodine receptor-2 gene variants with childhood asthma among human populations.

KLHL5 ATG3 RYR2

1.69e-07945323829686
Pubmed

Regulation of ryanodine receptor-dependent calcium signaling by polycystin-2.

RYR2 PKD2

1.64e-06245217404231
Pubmed

ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.

SEMA4B MAN1A2 PLD3 ZZEF1 LRP10 ABHD12 NEK9 CTSZ FURIN PKD2

2.46e-061201451035696571
Pubmed

Prevalence of arrhythmia-associated gene mutations and risk of sudden cardiac death in the Finnish population.

PKP2 RYR2

4.91e-06345223651034
Pubmed

The ret finger protein-like 4 gene, Rfpl4, encodes a putative E3 ubiquitin-protein ligase expressed in adult germ cells.

RFPL4A RFPL4AL1

1.63e-05545211850190
Pubmed

RFPL4 interacts with oocyte proteins of the ubiquitin-proteasome degradation pathway.

RFPL4A RFPL4AL1

4.56e-05845212525704
Pubmed

Arrhythmogenic Right Ventricular Cardiomyopathy Overview

PKP2 RYR2

7.32e-051045220301310
Pubmed

Irisin Mediates Effects on Bone and Fat via αV Integrin Receptors.

SEMA4B PLAT MAN1A2 PLD3 SLIRP CTSZ FURIN TRIM17 PKD2

8.51e-05145145930550785
Pubmed

Functional proteomics mapping of a human signaling pathway.

PKP2 MAN1A2 ZZEF1 SDK1 RYR2 SMAD9

1.09e-0459145615231748
Pubmed

Furin, a transcriptional target of NKX2-5, has an essential role in heart development and function.

FURIN SMAD9

1.27e-041345230840660
Pubmed

A Pellino-2 variant is associated with constitutive NLRP3 inflammasome activation in a family with ocular pterygium-digital keloid dysplasia.

FSCN2 NEK9

1.47e-041445236776133
Pubmed

Proteomic analysis of human parotid gland exosomes by multidimensional protein identification technology (MudPIT).

CES3 MAN1A2 DMBT1 PLD3 FURIN

1.99e-0441745519199708
Pubmed

β1-Integrin Deletion From the Lens Activates Cellular Stress Responses Leading to Apoptosis and Fibrosis.

PLAT SMAD9

2.47e-041845228763805
Pubmed

Prediction of the coding sequences of unidentified human genes. XIX. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.

CNTNAP4 SEMA4B WNK2

3.18e-0410245311214970
Pubmed

Peptidic degron in EID1 is recognized by an SCF E3 ligase complex containing the orphan F-box protein FBXO21.

DMBT1 SLIRP

3.72e-042245226631746
Pubmed

Multilevel proteomics reveals host perturbations by SARS-CoV-2 and SARS-CoV.

SEMA4B PLD3 ARSL LRP10 NEK9 FURIN DLGAP4

3.97e-04106145733845483
Pubmed

Hedgehog signalling controls sinoatrial node development and atrioventricular cushion formation.

RYR2 SMAD9

4.44e-042445234062094
Pubmed

Interpreting cancer genomes using systematic host network perturbations by tumour virus proteins.

PLD3 LRP10 SLIRP ABHD12 PKD2

4.54e-0449945522810586
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

SEMA4B MIB2 ZZEF1 CTSZ WNK2 FURIN HIRA

5.07e-04110545735748872
Pubmed

A SARS-CoV-2 protein interaction map reveals targets for drug repurposing.

PKP2 PLAT PLD3 NEK9

5.97e-0429845432353859
Pubmed

ELAVL2-directed RNA regulatory network drives the formation of quiescent primordial follicles.

RFPL4A RFPL4AL1

7.43e-043145231657143
Pubmed

NOBOX deficiency disrupts early folliculogenesis and oocyte-specific gene expression.

RFPL4A RFPL4AL1

1.06e-033745215326356
Pubmed

TGFβ attenuates cartilage extracellular matrix degradation via enhancing FBXO6-mediated MMP14 ubiquitination.

PLAT PLD3 LRP10

1.26e-0316445332409323
Pubmed

Sequence comparison of human and mouse genes reveals a homologous block structure in the promoter regions.

CASP8AP2 XPNPEP2 PLD3 ARSL SLIRP TPP1 FURIN

1.27e-03129345715342556
GeneFamilyZinc fingers ZZ-type|Lysine acetyltransferases

MIB2 ZZEF1

3.48e-041828291
GeneFamilyEF-hand domain containing

ZZEF1 RYR2 PKD2

4.59e-03219283863
CoexpressionAtlasdev gonad_e11.5_F_SupCellPrec_Sry_top-relative-expression-ranked_200

PKP2 KLHL5 CNTNAP5 PNLIP RYR2

2.40e-05171435gudmap_dev gonad_e11.5_F_SupCellPrec_Sry_200
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CNTNAP4 TMPRSS15 USH2A SDK1 RYR2

1.16e-06184455ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CNTNAP4 TMPRSS15 USH2A SDK1 RYR2

1.16e-061844552cbed6462fea2622871bb7e49b0df3d984239281
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CNTNAP4 TMPRSS15 USH2A SDK1 RYR2

1.16e-061844552b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell5'-Adult-Distal_Rectal-Epithelial-Tuft-related|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CES3 PKP2 SEMA4B DMBT1 WNK2

1.22e-061864554046b701aa29712d9f7c774f8955215122c3c003
ToppCell5'-Adult-Distal_Rectal-Epithelial-Tuft-related-BEST4+_epithelial|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CES3 PKP2 SEMA4B DMBT1 WNK2

1.22e-06186455bd5837033c1ffcbe5dd30195cc4846a2ba351bcd
ToppCellfacs-Lung-Endomucin-24m-Endothelial-Capillary_Type_1_Cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CNTNAP5 DMBT1 USH2A WNK2

1.39e-0514545496712c68ab759d7ade0d912581a1a7c25dc6def8
ToppCellCOVID-19-kidney-Technical/muscle_(PCT)|kidney / Disease (COVID-19 only), tissue and cell type

CNTNAP4 CNTNAP5 USH2A RYR2

1.43e-05146454c55f1bdb6ac43b4118cb27ea7c879527e1afcbab
ToppCellCOVID-19-kidney-Technical/muscle_(Mes)|COVID-19 / Disease (COVID-19 only), tissue and cell type

CNTNAP4 TMPRSS15 CNTNAP5 USH2A

1.51e-05148454d6ac5972267254651dfbe16bb4e9a62228093cc7
ToppCellCOVID-19-kidney-Technical/muscle_(Imm)|COVID-19 / Disease (COVID-19 only), tissue and cell type

CNTNAP4 TMPRSS15 CNTNAP5 USH2A

1.59e-051504540205318a870e091add66ee4305747dda9f51510d
ToppCellfacs-Lung-24m-Endothelial-capillary_endothelial-capillary_endothelial_cell-capillary_type_1_endothelial_cell|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CNTNAP5 DMBT1 USH2A WNK2

2.15e-05162454bf886e22ff2a20353499004b53f25fb9e6574896
ToppCellCOVID-19-kidney-Technical/muscle_(Imm)|kidney / Disease (COVID-19 only), tissue and cell type

CNTNAP4 CNTNAP5 USH2A RYR2

2.20e-0516345419c28ce16a588a7f4a035c32726f6ccd67702b5b
ToppCellmetastatic_Lymph_Node-Myeloid_cells-CD141+_DCs|metastatic_Lymph_Node / Location, Cell class and cell subclass

RFPL4A ATG3 RYR2 RFPL4AL1

2.37e-051664549f14e3ef19d5903278c040be1c477501237173fa
ToppCellfacs-Marrow-B-cells-24m|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CNTNAP4 PNLIP USH2A RYR2

2.91e-05175454887e75fc90e59a6394d62f3c048a9cfdf6707725
ToppCellPND14-Immune-Immune_Myeloid-Monocytic-Macrophage-AM-AM_mature|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PLD3 ABHD12 CTSZ FURIN

2.97e-05176454b0b87eebcf5c994386b39ca607e17f10e9d9de74
ToppCell15-Airway-Epithelial-Submucosal_gland|Airway / Age, Tissue, Lineage and Cell class

CES3 PKP2 DMBT1 WNK2

3.25e-05180454283bb0d58811947bfda4e286b9ec87d869c8e29e
ToppCelldroplet-Lung-nan-3m-Myeloid-Alveolar_Macrophage|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CES3 PLD3 ABHD12 FURIN

3.46e-05183454ec3c05b9ce1e0fbb720e0dea41f1e28fd3fd878f
ToppCellcellseq-Epithelial-Epithelial_Glandular-Serous|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

CES3 DMBT1 WNK2 TECPR1

3.54e-05184454f0cbb5b76e092be4188a9804ef5cf7a83cd7644f
ToppCellcellseq-Epithelial-Epithelial_Glandular-Serous-Serous|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

CES3 DMBT1 WNK2 TECPR1

3.54e-051844545433ba7bbab553ff668619822d1a9208e15cd59f
ToppCellfacs-Thymus|facs / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PLD3 PNLIP SPSB1 TECPR1

3.54e-0518445458beef66bbbde2479ec69dfef392d5941cedf230
ToppCelldroplet-Thymus-nan-21m-Lymphocytic-double_negative_T_cell|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PLD3 LRP10 SPSB1 TECPR1

3.85e-05188454e0184d9f6687d7ecb8fc461294ff7208f49c437c
ToppCellnucseq-Immune-Immune_Myeloid-Myeloid_Dendritic-cDC1|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

RFPL4A ATG3 SDK1 RFPL4AL1

3.85e-05188454d5ce3ffe783c322b4765b790e861727e46bc34b3
ToppCell5'-GW_trimst-2-LargeIntestine-Epithelial-epithelial_progenitor_cell-Stem_cells|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PKP2 DMBT1 ARSL CLDND2

4.09e-05191454a8d77095ba20b47fc70ba04f80759fbce873253d
ToppCell3'_v3-lymph-node_spleen-Lymphocytic_B-ABC_aged-B_memory|lymph-node_spleen / Manually curated celltypes from each tissue

CNTNAP4 FCRL2 SEMA4B CTSZ

4.09e-05191454c3ca8077da8594fb493e47ac4dfbbd20bfc14b37
ToppCellILEUM-inflamed-(3)_DC1|inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

RFPL4A ATG3 CTSZ RFPL4AL1

4.09e-05191454e77a6cace0d5a0463ad770e1b73fabbcb6f2d45f
ToppCellwk_20-22-Hematologic-Myeloid-DC1|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

RFPL4A ATG3 CTSZ RFPL4AL1

4.26e-05193454a260d943e9db966e4ce7d642313fd11354c2d2ba
ToppCellwk_15-18-Hematologic-Myeloid-DC1|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

RFPL4A ATG3 CTSZ RFPL4AL1

4.26e-05193454df9a4a459af51c2040ad832b580c333a135e374e
ToppCell5'-GW_trimst-2-LargeIntestine-Epithelial-epithelial_progenitor_cell|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PKP2 DMBT1 ARSL CLDND2

4.44e-05195454702dc7397c4a3ee50bb97ca24b9ab0d9b07fec9b
ToppCell3'-Pediatric_IBD-SmallIntestine-Epithelial-epithelial_progenitor_cell-Stem_cells|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PKP2 DMBT1 ARSL WNK2

4.53e-0519645497324c9e93f833e1f218e81fb53066d44c6892df
ToppCell3'-Pediatric_IBD-SmallIntestine-Epithelial-epithelial_progenitor_cell|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PKP2 DMBT1 ARSL WNK2

4.62e-05197454c0250509836f1be04f5e54386191d7bb1e1da652
ToppCellTracheal-NucSeq-Epithelial-Epi_airway_basal-Suprabasal|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

SEMA4B PLAT SDK1 SPSB1

4.71e-0519845419d8ff3a4f911b13ecc34844202925475ad4d2ab
ToppCelltumor_Lung-Myeloid_cells-mo-Mac|Myeloid_cells / Location, Cell class and cell subclass

PLD3 ABHD12 TPP1 CTSZ

4.89e-0520045458ff8db0ecf71daa86f9a38208e0d9b712cac0b5
ToppCellParenchymal-NucSeq-Epithelial-Epi_submucosal-gland-SMG_Duct|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

PKP2 KLHL5 SDK1 WNK2

4.89e-05200454b992eeddee38e6fe3564e9b1850f6b20b89bf47d
ToppCellTracheal-NucSeq-Epithelial-Epi_submucosal-gland-SMG_Serous|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

PKP2 DMBT1 WNK2 TECPR1

4.89e-052004547c2d499af60654b7b28f172ac2c914ad49fb74b4
ToppCellCOVID-19-kidney-Technical/muscle_(EC)|COVID-19 / Disease (COVID-19 only), tissue and cell type

CNTNAP4 CNTNAP5 USH2A

2.92e-0412845391072ca56bce2c552a95edd67e17f43d8cc1de95
ToppCellCOVID-19-kidney-Epithelial_Doublet|COVID-19 / Disease (COVID-19 only), tissue and cell type

CNTNAP4 TMPRSS15 CNTNAP5

3.06e-041304531ff28e9d3dc9a791e07d815f8fbb48f75d3f275b
ToppCellLPS-IL1RA-Stromal_mesenchymal-Fibroblasts-Pericyte_2|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

HAAO SEMA4B RYR2

5.41e-041584537f5426585d0d299d2b48e5fcb349950feffdef33
ToppCellfacs-Thymus-Thymus_Flowthrough-18m-Epithelial|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DMBT1 CLDND2 WNK2

5.41e-0415845312661763d1c309106801cb710c04cd2b62d16cba
ToppCellfacs-Thymus-Thymus_Flowthrough-18m-Epithelial-TECs|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DMBT1 CLDND2 WNK2

5.41e-041584530792c39e6fc0745095af7812de2d50949540d60f
ToppCellwk_20-22-Epithelial-Proximal_epithelial-SMG_basal_1|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

PKP2 WNK2 TRIM17

5.41e-04158453adad97e6cf479d42791c5ba9cbc5f15f469322bf
ToppCellfacs-Thymus-Thymus_Flowthrough-18m-Epithelial-epithelial_cell_of_thymus|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DMBT1 CLDND2 WNK2

5.41e-04158453e7db50d6dfaf7280a73a0d5b5aa4f43ea2762d72
ToppCellCOVID-19-kidney-Technical/muscle_(Mes)|kidney / Disease (COVID-19 only), tissue and cell type

CNTNAP5 USH2A RYR2

5.51e-041594535335cbcdeaf2bbd0268bbfe0e45c8c0d288e640d
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-precursor_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CNTNAP4 USH2A RYR2

5.61e-04160453c381ec6be8cf887861cc18f831a20db42f953fe1
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-pre_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CNTNAP4 USH2A RYR2

5.61e-0416045325c8f3d2a6d14ff0ca0b965fce89d3ff22f40585
ToppCellAdult-Mesenchymal-myofibroblast_cell-D175|Adult / Lineage, Cell type, age group and donor

FSCN2 PLAT XPNPEP2

5.72e-04161453048b7dc00746987a24bf870d4d278c4183eb04a2
ToppCellfacs-Pancreas-Exocrine-24m-Epithelial-pancreatic_acinar_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DMBT1 PNLIP RYR2

5.72e-04161453b9a17f41426bf715f30bf544a6795afaf37a3aa6
ToppCellfacs-Pancreas-Exocrine-24m-Epithelial-pancreatic_acinar_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DMBT1 PNLIP RYR2

5.72e-04161453f7a89c481f789f624102857be722c95fbeb47595
ToppCellPND07-28-samps-Myeloid-Macrophage|PND07-28-samps / Age Group, Lineage, Cell class and subclass

PLD3 ABHD12 CTSZ

5.82e-041624537c73fe8388af370461e04097cf145cbc9847285b
ToppCelldroplet-Marrow-BM-30m-Lymphocytic-NK_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HAAO PNLIP ABHD12

6.03e-04164453b77995958c938e10a526118f75d78cee72e0b207
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PKP2 CNTNAP5 SMAD9

6.03e-04164453d847d509bb1791638032ade6755d8164586b5bd5
ToppCellPND01-03-samps-Myeloid-Macrophage|PND01-03-samps / Age Group, Lineage, Cell class and subclass

PLD3 ABHD12 CTSZ

6.03e-0416445349733a9d3d95f05056b5b01916060ff20a8de3cf
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Pvalb-Pvalb_Reln_Tac1|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

CNTNAP4 CNTNAP5 FURIN

6.25e-0416645359d47c1fca7a8c70f6998f3367a9dbcb9b67966f
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Outer_Medullary_Collecting_Duct_Intercalated_Cell_Type_A|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PKP2 CNTNAP5 SMAD9

6.25e-041664536fe8db8d45177a78605681f22e04fa8d0594f2df
ToppCellPBMC-Mild-Myeloid-cDC-cDC-cDC_11|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

PKP2 RFPL4A SDK1

6.25e-04166453b1bebcbe17386cb102b11d551e62d46156ce0c68
ToppCellPBMC-Mild-Myeloid-cDC-cDC-cDC_11|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

PKP2 RFPL4A SDK1

6.36e-04167453e44743b20a7435c579d8e999ddc4ca119d6753f2
ToppCellmetastatic_Lymph_Node-Myeloid_cells-CD141+_DCs|Myeloid_cells / Location, Cell class and cell subclass

RFPL4A RYR2 RFPL4AL1

6.58e-04169453a4204bdd75837f5fee9aaac459cb4c19ee2a7bf4
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_1-Inh_L1_SST_CXCL14|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CNTNAP4 PKP2 SDK1

6.58e-041694536a2ef66d7ff69a92e8c62759482e823a07352440
ToppCellCOVID-19-Heart-CM_+_Macrophage|COVID-19 / Disease (COVID-19 only), tissue and cell type

PKP2 WNK2 RYR2

6.69e-041704533f15242a1d3e4e9871d9170b2ef05842fb609c29
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_no-steroids-Myeloid-Macrophage-macrophage,_alveolar-Macro_c3-EREG|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

ABHD12 TPP1 CTSZ

6.69e-041704539ac1ef57f14418a5dd2aa16861c3df698c28f5ed
ToppCelldroplet-Marrow-nan-18m-Lymphocytic-plasma_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PLD3 SPSB1 PKD2

6.69e-04170453067657ca7fcf5a0ffbd168b5c4609a30ca508f22
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2-Inh_L2-4_VIP_DSEL|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PKP2 PLAT SDK1

6.81e-041714532c7d73f1386ddd172839734c68ed3859a90f80f8
ToppCell10x5'-GI_small-bowel-Lymphocytic_T_CD8-Tem/emra_CD8|GI_small-bowel / Manually curated celltypes from each tissue

TMPRSS15 DMBT1 WNK2

6.81e-04171453f28684ea0e74a22f4c140658496068e28a6d3605
ToppCellPND07-Immune-Immune_Myeloid-Monocytic-Macrophage-AM-AM_mature|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PLD3 ABHD12 CTSZ

6.92e-04172453584af6537685cb459bf0fc298e6f46872016c116
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_1-Inh_L1_SST_CXCL14|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CNTNAP4 PKP2 SDK1

7.04e-04173453af85fb9f6e26a044ca4d23e5872039b1a7b73b1b
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Glomerular_Capillary_Endothelial_Cell_prolif|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CASP8AP2 PLAT SMAD9

7.04e-04173453f193c63cc536d891c9d23043765e320252bb6e65
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_1-Inh_L1_SST_CXCL14|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CNTNAP4 PKP2 SDK1

7.04e-041734530ba64e5385fe714f876002520f8b5202809bf11e
ToppCelldroplet-Marrow-nan-18m-Myeloid-basophil|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HAAO PLD3 ZZEF1

7.16e-0417445355cc8300489d11322724159ec7d0e1d32a702e91
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PNLIP USH2A RYR2

7.40e-04176453c6484334187f64cd00cd35e77d8ae436556b4260
ToppCelldroplet-Lung-3m-Hematologic-myeloid-alveolar_macrophage|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

PLD3 ABHD12 FURIN

7.40e-04176453e74ad0db3b05897edcfabeb11008ede2b9eeb638
ToppCellPND03-Immune-Immune_Myeloid-Monocytic-Macrophage-AM-AM_prolif|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PLD3 ABHD12 CTSZ

7.40e-04176453270d7908dbd84028958d257f94941dc685e20255
ToppCellFetal_29-31_weeks-Epithelial-club_cell-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

SEMA4B SDK1 WNK2

7.40e-041764533bbac5c2397535631fce8fa98f6ddb4fe0260351
ToppCellPND14-Immune-Immune_Myeloid-Monocytic-Macrophage-AM|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PLD3 ABHD12 CTSZ

7.52e-0417745367cc3a6461db5e0678f96b18224aeb83ad34b0f4
ToppCelldroplet-Lung-3m-Hematologic-myeloid-alveolar_macrophage-alveolar_macrophage|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

PLD3 ABHD12 FURIN

7.52e-0417745371919b5c9bfa87fdd2cd44dfa057b66ea081be5d
ToppCellSevere-CD4+_T_activated|Severe / Disease group and Cell class

PKP2 SDK1 RYR2

7.52e-04177453a08f170f1143fcdd7d0842a54d9b807a4548f8b7
ToppCellICU-NoSEP-Myeloid-cDC1|ICU-NoSEP / Disease, Lineage and Cell Type

FSCN2 PKP2 ARSL

7.52e-0417745333cd2c183ee8b597012efcbcae72131ac6beaf4e
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_1-Inh_L1_ADARB2_ADAM33|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CES3 CNTNAP4 SDK1

7.52e-041774531cb78133ac09ea3a3f5b5de07151033998406512
ToppCell343B-Lymphocytic-CD4_T-cell-CD4+_Effector_T_cell-2|343B / Donor, Lineage, Cell class and subclass (all cells)

NEK9 SPSB1 HIRA

7.65e-041784535289ac61637224ae70ffbc2d164d73116f10af40
ToppCellClub_cells-SSc-ILD_01|World / lung cells shred on cell class, cell subclass, sample id

DMBT1 SDK1 WNK2

7.65e-04178453be64d4be23fb96a4cdd7980c58880fdfe817747f
ToppCell343B-Lymphocytic-CD4_T-cell-CD4+_Effector_T_cell-2|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

NEK9 SPSB1 HIRA

7.65e-041784538151e5d73407fd9cba382b69a2bc707c81790c7f
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_1-Inh_L1_SST_CXCL14|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CNTNAP4 PKP2 SDK1

7.77e-04179453c7afbd10072d36a35cd20ae73670d76b9cefd22d
ToppCell3'-Pediatric_IBD-SmallIntestine-Epithelial-mature_enterocytic-Paneth|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PKP2 DMBT1 ARSL

7.77e-041794536405010e8136a4d9bab356f628e36e3194911112
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_1|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CNTNAP4 PKP2 SDK1

7.77e-0417945397ba67a856680f24846244c0b92c886cc0e79537
ToppCell3'-Pediatric_IBD-SmallIntestine-Epithelial-Tuft-related-BEST4+_epithelial|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CES3 DMBT1 WNK2

7.90e-041804537c7c4d64ff99d0710a7d19d8bc29fc9217394db1
ToppCell(5)_Epithelial_cells-(5)_Glands_mucous|(5)_Epithelial_cells / Oesophagus cell shreds on cell class (v1) and cell subclass (v1)

DMBT1 RYR2 SMAD9

7.90e-04180453a4118adaf4b09e2ca01b662ed60e7bbf32a24d58
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_1-Inh_L1_SST_CXCL14|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CNTNAP4 PKP2 SDK1

7.90e-04180453b6efdb4d319ef6f87f559acd974e5a71b06a2322
ToppCell5'-Airway_Nasal-Epithelial-Neuro-endocrine/ionocytic-ionocyte-Ionocyte|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PKP2 CNTNAP5 WNK2

8.02e-041814532b53a65ca5616a7b9f64232c3e0b7212d1e2f063
ToppCell5'-Airway_Nasal-Epithelial-Neuro-endocrine/ionocytic-ionocyte|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PKP2 CNTNAP5 WNK2

8.02e-041814536aef84616e8d2faf54b7e9e6cd02f33c3066dabc
ToppCell3'-GW_trimst-1.5-SmallIntestine-Epithelial-Tuft-related|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

DMBT1 CTSZ WNK2

8.02e-041814531d3d1b5a6efe9cedd03b7e0b5684df97f0246729
ToppCellwk_08-11-Mesenchymal-Fibroblast-Mesenchymal_1|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

PLAT CNTNAP5 SPSB1

8.02e-041814537e3bcfa2ba5b98a7df5854aa6e7a31e9a71faa8a
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD|renal_cortex_nuclei / Celltypes from Cells and Nuclei per compartment and clinical group

XPNPEP2 USH2A RYR2

8.02e-04181453c80ffa2ded5975a88e9a1a7d333196f95237bf0a
ToppCell5'-Airway_Nasal-Epithelial-Neuro-endocrine/ionocytic-ionocyte-Ionocyte-Ionocyte_L.0.7.0.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PKP2 CNTNAP5 WNK2

8.02e-0418145340df0afcb6848202da54670e84f22d7c3a515d01
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2-Inh_L2-5_VIP_TOX2|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CNTNAP4 PKP2 SDK1

8.02e-04181453154d5e586cab25155c6d06dfe6ae01203b88e0fb
ToppCell3'-Pediatric_IBD-SmallIntestine-Hematopoietic-Myeloid-cDC1|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract

RFPL4A ATG3 RFPL4AL1

8.02e-0418145384ca8c9c036478a6d3a2071919d09065455d417c
ToppCellILEUM-non-inflamed-(3)_DC1|non-inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

RFPL4A CTSZ RFPL4AL1

8.02e-04181453c9f53720249c8569598cc859e43e35c5f3f8475a
ToppCell3'-GW_trimst-1.5-SmallIntestine-Epithelial-Tuft-related-BEST4+_epithelial|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

DMBT1 CTSZ WNK2

8.02e-041814530069e8308de932df43660bbe926637c57b8bf7f6
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2-Inh_L2-4_VIP_DSEL|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PKP2 PLAT SDK1

8.02e-0418145370eff83dd85691e977972c660731394d2fcf5cdf
ToppCell5'-Airway_Nasal-Epithelial-Neuro-endocrine/ionocytic|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PKP2 CNTNAP5 WNK2

8.02e-0418145340d3829ae4aaf81e8616c3499ff8933137fc1cc4
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_1|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CNTNAP4 PKP2 SDK1

8.15e-041824537dc61e901428cea04f00ebb0939a44d21a6145c6
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2-Inh_L2-5_VIP_TOX2|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CNTNAP4 PKP2 SDK1

8.15e-041824533d7a8d2ee2137b098248597058974ef5ae09c19e
ToppCelldroplet-Heart-HEART_(LV+RV_ONLY)-30m-Mesenchymal-cardiomyocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PKP2 WNK2 RYR2

8.15e-04182453c4a7007c864a9455a7e7447e28ccd380878a6a0f
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_2|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CNTNAP4 PKP2 SDK1

8.15e-04182453420a8fd30543e37a66ba0786215d056d308660d0
Drugcis-4,7,10,13,16,19-Docosahexaenoic acid ethyl ester; Up 200; 100uM; MCF7; HT_HG-U133A_EA

ZZEF1 TPP1 SPSB1 CTSZ DLGAP4

3.45e-05193445881_UP
DrugHaloperidol [52-86-8]; Up 200; 10.6uM; PC3; HT_HG-U133A

CES3 PKP2 ZZEF1 NEK9 TPP1

3.54e-051944454678_UP
Drug(d,l)-Tetrahydroberberine [522-97-4]; Down 200; 11.8uM; HL60; HT_HG-U133A

CES3 HAAO TMPRSS15 MAN1A2 RYR2

3.62e-051954452163_DN
DrugSulfisoxazole [127-69-5]; Up 200; 15uM; MCF7; HT_HG-U133A

XPNPEP2 MAN1A2 ZZEF1 NEK9 DLGAP4

3.71e-051964455622_UP
DrugEvoxine [522-11-2]; Up 200; 11.6uM; HL60; HT_HG-U133A

PLAT PLD3 FURIN RYR2 DLGAP4

3.81e-051974452186_UP
DrugIsoflupredone acetate [338-98-7]; Down 200; 9.6uM; MCF7; HT_HG-U133A

CES3 TMPRSS15 SPSB1 RYR2 HIRA

3.90e-051984455545_DN
DrugSaquinavir mesylate [149845-06-7]; Up 200; 5.2uM; MCF7; HT_HG-U133A

PLAT DMBT1 PLD3 FURIN HIRA

4.09e-052004456246_UP
DiseaseArrhythmogenic Right Ventricular Dysplasia

PKP2 RYR2

5.65e-063412C0349788
DiseaseAngioedema

PLAT XPNPEP2

2.82e-056412C0002994
Diseaseautosomal recessive intellectual developmental disorder (implicated_via_orthology)

CNTNAP4 CNTNAP5

5.25e-058412DOID:0060308 (implicated_via_orthology)
DiseaseAtaxias, Hereditary

ABHD12 TPP1

5.25e-058412C0004138
Diseaseautism spectrum disorder (implicated_via_orthology)

CNTNAP4 PKP2 CNTNAP5 DLGAP4

5.91e-05152414DOID:0060041 (implicated_via_orthology)
Diseasearrhythmogenic right ventricular cardiomyopathy (is_implicated_in)

PKP2 RYR2

8.42e-0510412DOID:0050431 (is_implicated_in)
DiseaseLeft ventricular noncompaction

PKP2 MIB2

1.70e-0414412C1960469
DiseaseDisorder of eye

FSCN2 USH2A ABHD12 TPP1

2.13e-04212414C0015397
DiseaseRetinitis Pigmentosa

FSCN2 USH2A ABHD12

4.11e-04104413C0035334

Protein segments in the cluster

PeptideGeneStartEntry
RGCGETQVGWHGETY

DPEP2NB

41

A0A0U1RQF7
SSIGYRVLQWTGASG

ARSL

106

P51690
TTYINHVVSVAGWGI

CTSZ

236

Q9UBR2
VLAGTSYAWERTQGS

HAAO

256

P46952
VTAVATQGGYGSSNW

CNTNAP4

91

Q9C0A0
GWVTHATYGERGTSQ

C1orf147

146

Q96MC9
VWSRSHYQVGEGSSN

CASP8AP2

226

Q9UKL3
GVGTDTNYVKRGSWS

DLGAP4

281

Q9Y2H0
GWVDTYHNTGITGIT

ATG3

106

Q9NT62
YIWGHSLGTGVATNL

ABHD12

241

Q8N2K0
VTERATYIGTSNWSG

PLD3

421

Q8IV08
GQAVVSYHTVAWSNG

LRP10

281

Q7Z4F1
VVTSRTSEVYVWGGG

NEK9

341

Q8TD19
VDWKGGSRTGYTQAS

PNLIP

121

P16233
SIAGWGTVVYQGTTA

TMPRSS15

911

P98073
FTSGRHYWEVDVGTS

RFPL4A

146

A6NLU0
VGGHDGWSYLNTVER

KLHL5

566

Q96PQ7
AAWAQGYTGHGIVVS

FURIN

136

P09958
WATNGVGRKVSHSYG

FURIN

411

P09958
RWGQYHTSVGGLGDS

MAN1A2

386

O60476
GTGNVTFSWYREATG

FCRL2

231

Q96LA5
VHYSTGSQWESTVVG

HIRA

966

P54198
WVHGGALITGAATSY

CES3

146

Q6UWW8
AGRVEIYHGGTWGTV

DMBT1

1896

Q9UGM3
QWTEGHSGDTPTTGY

SDK1

1921

Q7Z5N4
THLRVGWASTEGYSP

RYR2

691

Q92736
VATQGRYGSSDWVTS

CNTNAP5

91

Q8WYK1
VTWADGTTNVYRVGH

MIB2

201

Q96AX9
WYTGSHGSVCSDGER

FSCN2

431

O14926
VIASHEGGSVYSDWS

USH2A

1931

O75445
FTSGRHYWEVDVGTS

RFPL4AL1

146

F8VTS6
YGVFTSQWHRGTTEG

SEMA4B

341

Q9NPR2
GWGAEYHRQDVTSTP

SMAD9

421

O15198
TATNYWTRQQEGHSG

CLDND2

26

Q8NHS1
QGISYRGTWSTAESG

PLAT

131

P00750
VWITDVGSGFFGHTV

NHLRC3

121

Q5JS37
SVGYTTLVGNNHESW

SPSB1

126

Q96BD6
NSRGVVWGIGYDHTA

TECPR1

776

Q7Z6L1
GSSHWGIIATYSGAG

PKD2

376

Q13563
TGFHRGLGWVQFSSE

SLIRP

56

Q9GZT3
VGQTAFSSGRHYWEV

TRIM17

341

Q9Y577
YSAVHWVATLNVGSG

TOMM40L

201

Q969M1
TEWGYRFTVTAGHLG

ZZEF1

2786

O43149
SGGQYWDGTTDITRT

XPNPEP2

451

O43895
GARGQGWTVYHPTSE

WNK2

2071

Q9Y3S1
GRWGRGTAQYSSQKS

PKP2

121

Q99959
NISTWVYSSPGRHEG

TPP1

286

O14773