Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionRNA polymerase II transcription regulatory region sequence-specific DNA binding

IRX5 FOXO6 ARX DRGX GBX1 IRF3 POU5F1 POU5F1B IRX3 IRX1 DMBX1 IRX4 ZNF440 DHX9 ZNF711 MYPOP THRA BARHL1 BARHL2 PURG

4.20e-05145910220GO:0000977
GeneOntologyMolecularFunctionintronic transcription regulatory region sequence-specific DNA binding

POU5F1 POU5F1B THRA

8.35e-05171023GO:0001161
GeneOntologyMolecularFunctionDNA-binding transcription factor activity, RNA polymerase II-specific

IRX5 FOXO6 ARX DRGX GBX1 IRF3 POU5F1 POU5F1B IRX3 IRX1 DMBX1 IRX4 ZNF440 ZNF711 MYPOP THRA BARHL1 BARHL2 PURG

8.64e-05141210219GO:0000981
GeneOntologyMolecularFunctionDNA-binding transcription repressor activity, RNA polymerase II-specific

ARX IRF3 POU5F1 POU5F1B IRX3 IRX1 DMBX1 MYPOP

2.37e-043201028GO:0001227
GeneOntologyMolecularFunctionDNA-binding transcription repressor activity

ARX IRF3 POU5F1 POU5F1B IRX3 IRX1 DMBX1 MYPOP

2.68e-043261028GO:0001217
GeneOntologyMolecularFunction3'-5' RNA helicase activity

YTHDC2 DHX9

3.82e-0461022GO:0034458
GeneOntologyMolecularFunctionPOU domain binding

POU5F1 POU5F1B

5.34e-0471022GO:0070974
GeneOntologyBiologicalProcessnegative regulation of calcium ion-dependent exocytosis

POU5F1 POU5F1B ADRA2A

1.83e-05111013GO:0045955
GeneOntologyCellularComponentchromatin

IRX5 ERCC6 FOXO6 H1-7 ARX DRGX GBX1 IRF3 POU5F1 POU5F1B IRX3 IRX1 SRCAP DMBX1 IRX4 DHX9 ZNF711 THRA BARHL1 BARHL2 KAT6B

9.10e-06148010321GO:0000785
HumanPhenoPachygyria

COPB2 ARX GRIN1 FKTN MTOR ASPM MACF1 KAT6B

1.04e-05163358HP:0001302
HumanPhenoLissencephaly

COPB2 ARX GRIN1 FKTN MTOR ASPM MACF1 KAT6B

3.08e-05189358HP:0001339
DomainHomeobox_CS

IRX5 ARX DRGX GBX1 POU5F1 POU5F1B IRX3 IRX1 DMBX1 IRX4 BARHL1 BARHL2

3.26e-1018610012IPR017970
Domain-

IRX5 POGK ARX DRGX GBX1 POU5F1 POU5F1B IRX3 IRX1 DMBX1 IRX4 MYPOP BARHL1 BARHL2

3.36e-10283100141.10.10.60
DomainHomeodomain-like

IRX5 POGK ARX DRGX GBX1 POU5F1 POU5F1B IRX3 IRX1 DMBX1 IRX4 MYPOP BARHL1 BARHL2

2.67e-0933210014IPR009057
DomainHomeobox

IRX5 ARX DRGX GBX1 POU5F1 POU5F1B IRX3 IRX1 DMBX1 IRX4 BARHL1 BARHL2

4.48e-0923410012PF00046
DomainHOMEOBOX_1

IRX5 ARX DRGX GBX1 POU5F1 POU5F1B IRX3 IRX1 DMBX1 IRX4 BARHL1 BARHL2

4.94e-0923610012PS00027
DomainHOX

IRX5 ARX DRGX GBX1 POU5F1 POU5F1B IRX3 IRX1 DMBX1 IRX4 BARHL1 BARHL2

5.18e-0923710012SM00389
DomainHOMEOBOX_2

IRX5 ARX DRGX GBX1 POU5F1 POU5F1B IRX3 IRX1 DMBX1 IRX4 BARHL1 BARHL2

5.69e-0923910012PS50071
DomainHomeobox_dom

IRX5 ARX DRGX GBX1 POU5F1 POU5F1B IRX3 IRX1 DMBX1 IRX4 BARHL1 BARHL2

5.69e-0923910012IPR001356
DomainIRO

IRX5 IRX3 IRX1 IRX4

1.15e-0861004SM00548
DomainIroquois_homeo

IRX5 IRX3 IRX1 IRX4

1.15e-0861004IPR003893
DomainHomeobox_KN

IRX5 IRX3 IRX1 IRX4

1.75e-06171004PF05920
DomainHomeobox_KN_domain

IRX5 IRX3 IRX1 IRX4

1.75e-06171004IPR008422
DomainCoatomer_WDAD

COPA COPB2

2.84e-0521002PF04053
DomainCoatomer_WD-assoc_reg

COPA COPB2

2.84e-0521002IPR006692
DomainOAR

ARX DRGX DMBX1

6.47e-05151003PF03826
DomainOAR

ARX DRGX DMBX1

7.93e-05161003PS50803
DomainOAR_dom

ARX DRGX DMBX1

7.93e-05161003IPR003654
DomainPOU_dom_5

POU5F1 POU5F1B

8.48e-0531002IPR015585
DomainATP_Ca_trans_C

ATP2B2 ATP2B3

1.69e-0441002IPR022141
DomainATP_Ca_trans_C

ATP2B2 ATP2B3

1.69e-0441002PF12424
DomainP-type_ATPase_IIB

ATP2B2 ATP2B3

1.69e-0441002IPR006408
DomainHydrolase_3

ATP2B2 ATP2B3

1.24e-03101002PF08282
DomainPTBI

DOK1 DOK2

1.51e-03111002SM00310
DomainIRS_PTB

DOK1 DOK2

1.81e-03121002PS51064
DomainIRS

DOK1 DOK2

2.48e-03141002PF02174
DomainIRS_PTB

DOK1 DOK2

2.48e-03141002IPR002404
DomainHelicase_C

ERCC6 YTHDC2 SRCAP DHX9

2.62e-031071004PF00271
DomainHELICc

ERCC6 YTHDC2 SRCAP DHX9

2.62e-031071004SM00490
DomainHelicase_C

ERCC6 YTHDC2 SRCAP DHX9

2.71e-031081004IPR001650
DomainHELICASE_CTER

ERCC6 YTHDC2 SRCAP DHX9

2.80e-031091004PS51194
DomainHELICASE_ATP_BIND_1

ERCC6 YTHDC2 SRCAP DHX9

2.80e-031091004PS51192
DomainDEXDc

ERCC6 YTHDC2 SRCAP DHX9

2.80e-031091004SM00487
DomainHelicase_ATP-bd

ERCC6 YTHDC2 SRCAP DHX9

2.89e-031101004IPR014001
DomainPOU

POU5F1 POU5F1B

3.24e-03161002SM00352
DomainPOU_dom

POU5F1 POU5F1B

3.24e-03161002IPR000327
DomainPou

POU5F1 POU5F1B

3.24e-03161002PF00157
DomainPOU_1

POU5F1 POU5F1B

3.24e-03161002PS00035
DomainATPase_P-typ_TM_dom

ATP2B2 ATP2B3

3.24e-03161002IPR023298
DomainPOU_2

POU5F1 POU5F1B

3.24e-03161002PS00465
Domain-

ATP2B2 ATP2B3

3.24e-031610021.20.1110.10
DomainPOU_3

POU5F1 POU5F1B

3.24e-03161002PS51179
DomainATPase_P-typ_cation-transptr_C

ATP2B2 ATP2B3

3.66e-03171002IPR006068
DomainPOU

POU5F1 POU5F1B

3.66e-03171002IPR013847
DomainCation_ATPase_C

ATP2B2 ATP2B3

3.66e-03171002PF00689
DomainDUF1605

YTHDC2 DHX9

3.66e-03171002IPR011709
DomainOB_NTP_bind

YTHDC2 DHX9

3.66e-03171002PF07717
DomainCation_ATPase_N

ATP2B2 ATP2B3

4.11e-03181002PF00690
DomainHA2

YTHDC2 DHX9

4.11e-03181002SM00847
DomainCation_ATPase_N

ATP2B2 ATP2B3

4.11e-03181002SM00831
DomainHA2

YTHDC2 DHX9

4.11e-03181002PF04408
DomainHelicase-assoc_dom

YTHDC2 DHX9

4.11e-03181002IPR007502
DomainMyosin-like_IQ_dom

MYH14 ASPM

4.57e-03191002IPR027401
Domain-

MYH14 ASPM

4.57e-031910024.10.270.10
DomainATPase_P-typ_cation-transptr_N

ATP2B2 ATP2B3

4.57e-03191002IPR004014
DomainSOCS

RAB40A RAB40AL

5.06e-03201002SM00253
DomainCH

SPTB ASPM MACF1

5.12e-03651003SM00033
Pubmed

Comparison of Iroquois gene expression in limbs/fins of vertebrate embryos.

IRX5 IRX3 IRX1 IRX4

1.13e-096104420408909
Pubmed

Organization of mouse Iroquois homeobox genes in two clusters suggests a conserved regulation and function in vertebrate development.

IRX5 IRX3 IRX1 IRX4

1.13e-096104411042145
Pubmed

Iroquois homeobox 3 regulates odontoblast proliferation and differentiation mediated by Wnt5a expression.

IRX5 IRX3 IRX1 IRX4

1.13e-096104436773339
Pubmed

Regulated expression patterns of IRX-2, an Iroquois-class homeobox gene, in the human breast.

IRX5 IRX3 IRX1 IRX4

1.13e-096104410370142
Pubmed

The prepattern transcription factor Irx3 directs nephron segment identity.

IRX5 IRX3 IRX1 IRX4

2.62e-097104417875669
Pubmed

Sensitive nonradioactive detection of mRNA in tissue sections: novel application of the whole-mount in situ hybridization protocol.

IRX5 IRX3 IRX1 IRX4

5.23e-098104411118473
Pubmed

The Iroquois homeobox gene Irx2 is not essential for normal development of the heart and midbrain-hindbrain boundary in mice.

IRX5 IRX3 IRX1 IRX4

9.40e-099104414585979
Pubmed

Gene and cluster-specific expression of the Iroquois family members during mouse development.

IRX5 IRX3 IRX1 IRX4

9.40e-099104411520674
Pubmed

A census of human transcription factors: function, expression and evolution.

IRX5 ARX DRGX GBX1 IRF3 POU5F1 POU5F1B IRX3 IRX1 DMBX1 IRX4 ZNF711 MYPOP THRA BARHL1 BARHL2

1.27e-089081041619274049
Pubmed

Patterning the embryonic heart: identification of five mouse Iroquois homeobox genes in the developing heart.

IRX5 IRX3 IRX1 IRX4

2.45e-0811104410926765
Pubmed

The Hematopoietic TALE-Code Shows Normal Activity of IRX1 in Myeloid Progenitors and Reveals Ectopic Expression of IRX3 and IRX5 in Acute Myeloid Leukemia.

IRX5 IRX3 IRX1

2.60e-083104335328612
Pubmed

Iroquois genes influence proximo-distal morphogenesis during rat lung development.

IRX5 IRX3 IRX1

2.59e-075104316299054
Pubmed

Serine 347 Phosphorylation by JNKs Negatively Regulates OCT4 Protein Stability in Mouse Embryonic Stem Cells.

POU5F1 POU5F1B FBXW8

2.59e-075104329153991
Pubmed

Expression of two novel mouse Iroquois homeobox genes during neurogenesis.

IRX5 IRX3 IRX1

2.59e-075104310704856
Pubmed

Deletion of Mylk1 in oocytes causes delayed morula-to-blastocyst transition and reduced fertility without affecting folliculogenesis and oocyte maturation in mice.

MYLK POU5F1 POU5F1B

2.59e-075104325761595
Pubmed

Expression of Irx6 during mouse morphogenesis.

IRX5 IRX3 IRX4

2.59e-075104311335133
Pubmed

The E3 ubiquitin ligase HECTD1 contributes to cell proliferation through an effect on mitosis.

UTP6 RPL31 ERCC6 COPA RADX COPB2 YTHDC2 DHX9 ASPM ACIN1 MACF1 UTP20 NOP2

4.54e-077591041335915203
Pubmed

Kat6b Modulates Oct4 and Nanog Binding to Chromatin in Embryonic Stem Cells and Is Required for Efficient Neural Differentiation.

POU5F1 POU5F1B KAT6B

5.16e-076104330790630
Pubmed

Deficiency of splicing factor 1 suppresses the occurrence of testicular germ cell tumors.

POU5F1 POU5F1B SF1

5.16e-076104320736371
Pubmed

Germ cell-specific eIF4E1b regulates maternal mRNA translation to ensure zygotic genome activation.

POU5F1 POU5F1B EIF4E1B

5.16e-076104337257918
Pubmed

Primordial germ cell proliferation is impaired in Fused Toes mutant embryos.

IRX5 POU5F1 POU5F1B IRX3

5.29e-0722104420969841
Pubmed

Promyelocytic leukemia protein in retinoic acid-induced chromatin remodeling of Oct4 gene promoter.

POU5F1 POU5F1B SF1

9.01e-077104321360626
Pubmed

Mature mRNA processing that deletes 3' end sequences directs translational activation and embryonic development.

POU5F1 POU5F1B DHX9

9.01e-077104338000026
Pubmed

Cardiomyopathy in Irx4-deficient mice is preceded by abnormal ventricular gene expression.

IRX5 IRX3 IRX1 IRX4

1.07e-0626104411238910
Pubmed

Notch signaling is essential for ventricular chamber development.

IRX5 IRX3 IRX4 MEST

1.26e-0627104417336907
Pubmed

Identification of a novel mouse Iroquois homeobox gene, Irx5, and chromosomal localisation of all members of the mouse Iroquois gene family.

IRX5 IRX3 IRX1

1.44e-068104310822268
Pubmed

Identifying biological pathways that underlie primordial short stature using network analysis.

UTP6 COPA YTHDC2 LMNB2 SRCAP YWHAB SF1 DHX9 FBXW8 MYH14 ACIN1 MACF1 UTP20 NOP2

2.29e-0610241041424711643
Pubmed

Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.

UTP6 RPL31 ERCC6 COPA COPB2 LMNB2 SRCAP YWHAB DHX9 ARVCF MYH14 ASPM ACIN1 MACF1 UTP20 NOP2

2.66e-0613531041629467282
Pubmed

Network organization of the huntingtin proteomic interactome in mammalian brain.

SPTB POR SLC13A3 GRIN1 LMNB2 YWHAB ADCY6 DHX9 MTOR BARHL1 ATP2B2

2.68e-066211041122794259
Pubmed

The role of microtubule actin cross-linking factor 1 (MACF1) in the Wnt signaling pathway.

POU5F1 POU5F1B MACF1

4.21e-0611104316815997
Pubmed

Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.

UTP6 COPA COPB2 YTHDC2 LMNB2 MYH14 MTOR ACIN1 MACF1 UTP20 NOP2

4.32e-066531041122586326
Pubmed

Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.

UTP6 RPL31 COPA COPB2 POR YTHDC2 LMNB2 SF1 DHX9 MYH14 MTOR ACIN1 UTP20 NOP2 ATP2B3 TMEM117

5.14e-0614251041630948266
Pubmed

Impact of cytosine methylation on DNA binding specificities of human transcription factors.

IRX5 ARX DRGX IRF3 POU5F1 IRX3 IRX1 DMBX1 BARHL1 BARHL2

5.66e-065441041028473536
Pubmed

In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.

ADAP1 MYLK COPA LMNB2 SRCAP EPX YWHAB ADCY6 MYPOP MYH14 ASPM ACIN1 MACF1 IL1R1 ATP2B2 ATP2B3

5.96e-0614421041635575683
Pubmed

Sfrp1 and Sfrp2 are required for normal male sexual development in mice.

SFRP2 POU5F1 POU5F1B

7.27e-0613104319100252
Pubmed

Deficiency of lipopolysaccharide binding protein facilitates adipose browning, glucose uptake and oxygen consumption in mouse embryonic fibroblasts via activating PI3K/Akt/mTOR pathway and inhibiting autophagy.

LBP MTOR

8.86e-062104236710409
Pubmed

Identification of mouse blastocyst genes that are downregulated by double-stranded RNA-mediated knockdown of Oct-4 expression.

POU5F1 POU5F1B

8.86e-062104215685634
Pubmed

Dok-1 and Dok-2 Are Required To Maintain Herpes Simplex Virus 1-Specific CD8+ T Cells in a Murine Model of Ocular Infection.

DOK1 DOK2

8.86e-062104228490594
Pubmed

Nuclear and chromatin reorganization in the MHC-Oct3/4 locus at developmental phases of embryonic stem cell differentiation.

POU5F1 POU5F1B

8.86e-062104216950240
Pubmed

Maternal Oct-4 is a potential key regulator of the developmental competence of mouse oocytes.

POU5F1 POU5F1B

8.86e-062104218837968
Pubmed

Cruciform Formable Sequences within Pou5f1 Enhancer Are Indispensable for Mouse ES Cell Integrity.

POU5F1 POU5F1B

8.86e-062104233810223
Pubmed

Phosphorylation of Threonine343 Is Crucial for OCT4 Interaction with SOX2 in the Maintenance of Mouse Embryonic Stem Cell Pluripotency.

POU5F1 POU5F1B

8.86e-062104228988986
Pubmed

Cross-linking of human cytochrome P450 2B6 to NADPH-cytochrome P450 reductase: Identification of a potential site of interaction.

CYP2B6 POR

8.86e-062104220096935
Pubmed

Abnormal DNA methylation of the Oct-4 enhancer region in cloned mouse embryos.

POU5F1 POU5F1B

8.86e-062104218932201
Pubmed

Dok-1 is a positive regulator of IL-4 signalling and IgE response.

DOK1 DOK2

8.86e-062104217827176
Pubmed

A POU-domain transcription factor in early stem cells and germ cells of the mammalian embryo.

POU5F1 POU5F1B

8.86e-06210421972777
Pubmed

In vitro assembly and disassembly of coatomer.

COPA COPB2

8.86e-06210428537409
Pubmed

Mouse Oct-3 maps between the tcl12 embryonic lethal gene and the Qa gene in the H-2 complex.

POU5F1 POU5F1B

8.86e-06210421680810
Pubmed

NDR functions as a physiological YAP1 kinase in the intestinal epithelium.

STK38 STK38L

8.86e-062104225601544
Pubmed

IRX3 and IRX5 Inhibit Adipogenic Differentiation of Hypertrophic Chondrocytes and Promote Osteogenesis.

IRX5 IRX3

8.86e-062104232662900
Pubmed

Heterogeneous DNA methylation status of the regulatory element of the mouse Oct4 gene in adult somatic cell population.

POU5F1 POU5F1B

8.86e-062104215996113
Pubmed

Oct4 transcription factor in conjunction with valproic acid accelerates myelin repair in demyelinated optic chiasm in mice.

POU5F1 POU5F1B

8.86e-062104226804242
Pubmed

Conserved, developmentally regulated mechanism couples chromosomal looping and heterochromatin barrier activity at the homeobox gene A locus.

POU5F1 POU5F1B

8.86e-062104221502535
Pubmed

Phenotypic complementation establishes requirements for specific POU domain and generic transactivation function of Oct-3/4 in embryonic stem cells.

POU5F1 POU5F1B

8.86e-062104211839818
Pubmed

ADRA2A and IRX1 are putative risk genes for Raynaud's phenomenon.

IRX1 ADRA2A

8.86e-062104237828025
Pubmed

Dok-1 and Dok-2 are negative regulators of T cell receptor signaling.

DOK1 DOK2

8.86e-062104217329234
Pubmed

A novel Oct4/Pou5f1-like non-coding RNA controls neural maturation and mediates developmental effects of ethanol.

POU5F1 POU5F1B

8.86e-062104233221301
Pubmed

Developmental fate of embryonic germ cells (EGCs), in vivo and in vitro.

POU5F1 POU5F1B

8.86e-062104212641567
Pubmed

A nontranscriptional role for Oct4 in the regulation of mitotic entry.

POU5F1 POU5F1B

8.86e-062104225324523
Pubmed

Novel variants of Oct-3/4 gene expressed in mouse somatic cells.

POU5F1 POU5F1B

8.86e-062104218765667
Pubmed

Role of Dok-1 and Dok-2 in leukemia suppression.

DOK1 DOK2

8.86e-062104215611295
Pubmed

Role of Dok-1 and Dok-2 in myeloid homeostasis and suppression of leukemia.

DOK1 DOK2

8.86e-062104215611294
Pubmed

Oct4 dependence of chromatin structure within the extended Nanog locus in ES cells.

POU5F1 POU5F1B

8.86e-062104218283123
Pubmed

Mechanisms of OCT4 on 3,5,3'-Tri-iodothyronine and FSH-induced Granulosa Cell Development in Female Mice.

POU5F1 POU5F1B

8.86e-062104234463738
Pubmed

Differential expression of Oct3/4 in human breast cancer and normal tissues.

POU5F1 POU5F1B

8.86e-062104229620155
Pubmed

Glutamine Metabolism Regulates the Pluripotency Transcription Factor OCT4.

POU5F1 POU5F1B

8.86e-062104227346346
Pubmed

Critical POU domain residues confer Oct4 uniqueness in somatic cell reprogramming.

POU5F1 POU5F1B

8.86e-062104226877091
Pubmed

The embryonic Octamer factor 3/4 displays distinct DNA binding specificity from those of other Octamer factors.

POU5F1 POU5F1B

8.86e-062104212615074
Pubmed

Effect of ectopic expression of homeoprotein EGAM1C on the cell morphology, growth, and differentiation in a mouse embryonic stem cell line, MG1.19 cells.

POU5F1 POU5F1B

8.86e-062104222367590
Pubmed

Cytochrome P450 reductase dependent inhibition of cytochrome P450 2B1 activity: Implications for gene directed enzyme prodrug therapy.

CYP2B6 POR

8.86e-062104216887103
Pubmed

Targeted disruption of organic cation transporter 3 (Oct3) ameliorates ischemic brain damage through modulating histamine and regulatory T cells.

POU5F1 POU5F1B

8.86e-062104222739622
Pubmed

Oct-4: more than just a POUerful marker of the mammalian germline?

POU5F1 POU5F1B

8.86e-06210429524569
Pubmed

Transient pairing of homologous Oct4 alleles accompanies the onset of embryonic stem cell differentiation.

POU5F1 POU5F1B

8.86e-062104225748933
Pubmed

Localization of two genes encoding plasma membrane Ca2+ ATPases isoforms 2 (ATP2B2) and 3 (ATP2B3) to human chromosomes 3p26-->p25 and Xq28, respectively.

ATP2B2 ATP2B3

8.86e-06210428187550
Pubmed

Expression pattern of Oct-4 in preimplantation embryos of different species.

POU5F1 POU5F1B

8.86e-062104211090438
Pubmed

Phosphotyrosine binding-mediated oligomerization of downstream of tyrosine kinase (Dok)-1 and Dok-2 is involved in CD2-induced Dok phosphorylation.

DOK1 DOK2

8.86e-062104216177091
Pubmed

A saturating mutagenesis CRISPR-Cas9-mediated functional genomic screen identifies cis- and trans-regulatory elements of Oct4 in murine ESCs.

POU5F1 POU5F1B

8.86e-062104232994224
Pubmed

Effects of the selected cytochrome P450 oxidoreductase genetic polymorphisms on cytochrome P450 2B6 activity as measured by bupropion hydroxylation.

CYP2B6 POR

8.86e-062104226580670
Pubmed

Networks of Transcription Factors for Oct4 Expression in Mice.

POU5F1 POU5F1B

8.86e-062104228731785
Pubmed

Oct-4 controls cell-cycle progression of embryonic stem cells.

POU5F1 POU5F1B

8.86e-062104219968627
Pubmed

A defined Oct4 level governs cell state transitions of pluripotency entry and differentiation into all embryonic lineages.

POU5F1 POU5F1B

8.86e-062104223629142
Pubmed

Involvement of Oct3/4 in the enhancement of neuronal differentiation of ES cells in neurogenesis-inducing cultures.

POU5F1 POU5F1B

8.86e-062104212702663
Pubmed

Changes in the Expression of Pluripotency Factor Oct-4 and Intensity of Apoptosis in the Uterus during Spontaneous and Immune-Dependent Abortions in Mice.

POU5F1 POU5F1B

8.86e-062104235501657
Pubmed

Cutting edge: Dok-1 and Dok-2 adaptor molecules are regulated by phosphatidylinositol 5-phosphate production in T cells.

DOK1 DOK2

8.86e-062104219299694
Pubmed

Hierarchical Oct4 Binding in Concert with Primed Epigenetic Rearrangements during Somatic Cell Reprogramming.

POU5F1 POU5F1B

8.86e-062104226832419
Pubmed

Dok-1 and Dok-2 Regulate the Formation of Memory CD8+ T Cells.

DOK1 DOK2

8.86e-062104227664281
Pubmed

Oct4 was a novel target of Wnt signaling pathway.

POU5F1 POU5F1B

8.86e-062104222120493
Pubmed

Analysis of a transgenic Oct4 enhancer reveals high fidelity long-range chromosomal interactions.

POU5F1 POU5F1B

8.86e-062104226435056
Pubmed

Differential expression of the Oct-4 transcription factor during mouse germ cell differentiation.

POU5F1 POU5F1B

8.86e-06210429507072
Pubmed

Oct-3/4 repression accelerates differentiation of neural progenitor cells in vitro and in vivo.

POU5F1 POU5F1B

8.86e-062104215548425
Pubmed

OCT4 interprets and enhances nucleosome flexibility.

POU5F1 POU5F1B

8.86e-062104236130732
Pubmed

Computational analysis of single-cell transcriptomics data elucidates the stabilization of Oct4 expression in the E3.25 mouse preimplantation embryo.

POU5F1 POU5F1B

8.86e-062104231222057
Pubmed

The molecular biology of Oct-4 in the early mouse embryo.

POU5F1 POU5F1B

8.86e-06210429835353
Pubmed

OCT4B mediates hypoxia-induced cancer dissemination.

POU5F1 POU5F1B

8.86e-062104230209362
Pubmed

POU5F1 Protein and Gene Expression Analysis in Neonate and Adult Mouse Testicular Germ Cells by Immunohistochemistry and Immunocytochemistry.

POU5F1 POU5F1B

8.86e-062104234788058
Pubmed

The Iroquois homeobox proteins IRX3 and IRX5 have distinct roles in Wilms tumour development and human nephrogenesis.

IRX5 IRX3

8.86e-062104230246301
Pubmed

Dok1 and Dok2 proteins regulate natural killer cell development and function.

DOK1 DOK2

8.86e-062104224963146
Pubmed

Sumoylation of Oct4 enhances its stability, DNA binding, and transactivation.

POU5F1 POU5F1B

8.86e-062104217525163
Pubmed

Auxin-degron system identifies immediate mechanisms of OCT4.

POU5F1 POU5F1B

8.86e-062104234143975
Pubmed

Acidic extracellular pH of tumors induces octamer-binding transcription factor 4 expression in murine fibroblasts in vitro and in vivo.

POU5F1 POU5F1B

8.86e-062104227302093
InteractionCYP2B6 interactions

CYP2B6 ATP2B2 ATP2B3

6.72e-0681013int:CYP2B6
Cytoband5p15.3

IRX1 IRX4

2.26e-041010425p15.3
Cytoband2q12

MGAT4A IL1R1

3.31e-041210422q12
GeneFamilyTALE class homeoboxes and pseudogenes

IRX5 IRX3 IRX1 IRX4

4.93e-0626804526
GeneFamilyATPases Ca2+ transporting

ATP2B2 ATP2B3

6.82e-0498021209
CoexpressionMIKKELSEN_MCV6_HCP_WITH_H3K27ME3

NEIL2 ARX DRGX GBX1 IRX1 PANX2 SSTR1 IRX4 ATP2B2 ATP2B3

9.87e-0643810410M1954
CoexpressionMIKKELSEN_MCV6_HCP_WITH_H3K27ME3

NEIL2 ARX DRGX GBX1 IRX1 PANX2 SSTR1 IRX4 ATP2B2 ATP2B3

1.03e-0544010410MM832
ToppCellfacs-Brain_Non-Myeloid-Hippocampus-3m-Neuronal-neuron|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FOXO6 NEIL2 GRIN1 BARHL2 MCTP2 CDH4

4.01e-061791046479116ac65488c60104a053530830763ec1f95b2
ToppCellfacs-Brain_Non-Myeloid-Hippocampus-3m-Neuronal-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FOXO6 NEIL2 GRIN1 BARHL2 MCTP2 CDH4

4.01e-0617910461dfc0cb8b369aef35c59f3d4c52603dc9f3728c1
ToppCell3'_v3-lymph-node_spleen-Hematopoietic_Erythro-Mega|lymph-node_spleen / Manually curated celltypes from each tissue

MYLK IRX1 PKD1L3 MEST PLA2G4C MYH14

4.01e-0617910464e0cf069bc47328eda753a4edc7e89b8915d52bb
ToppCellfacs-Brain_Non-Myeloid-Hippocampus-3m-Neuronal|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FOXO6 NEIL2 GRIN1 BARHL2 MCTP2 CDH4

4.01e-06179104669a1b3b05c921de6343ffe6ad998aa2b804312a7
ToppCellfacs-Brain_Non-Myeloid-Striatum_-18m-Neuronal-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SPTB GRIN1 IRX1 PANX2 BARHL2 PALS2

5.15e-061871046ef3c85c01bc3da408ae288b6e3096ad888a12e63
ToppCellfacs-Marrow-KLS-18m-Myeloid-granulocyte_monocyte_progenitor_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADAP1 LMNB2 LBP PCYOX1L POGLUT2 NOP2

6.17e-061931046f92bbe70e6c725bfb8c08bfc2a94e375528151a3
ToppCellfacs-Marrow-KLS-18m-Myeloid-granulocyte_monocyte_progenitor_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADAP1 LMNB2 LBP PCYOX1L POGLUT2 NOP2

6.17e-06193104644ba79db566d0fa3bbcfe3adf9164bf8c3cb0bc3
ToppCellLPS-IL1RA-Unknown-Endothelial|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SFRP2 MGAT4A ADAMTSL3 PLA2G4C ASPM

8.52e-061181045aefad0b35aff980b6a2a98057735442e8a65ab04
ToppCellLPS-IL1RA-Unknown|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SFRP2 MGAT4A ADAMTSL3 PLA2G4C ASPM

8.52e-0611810456cb4063b83f867b782080ce5b1199b51bb277f2a
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Calb2_Necab1|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

SFRP2 SPTB ARX SSTR1 CDH4

1.17e-051261045a4fc7ac4931d2fc8aa8196a62d809b698937aa9c
ToppCellPND01-03-samps-Mesenchymal-Myofibroblast-myofibroblast_-_mature_-_B|PND01-03-samps / Age Group, Lineage, Cell class and subclass

SFRP2 GRIN1 MTMR11 STK38L OR2H2

1.82e-0513810458d70e64843f7c3be8ee4203cc126fdf1001f0df5
ToppCellTCGA-Brain-Recurrent_Tumor|TCGA-Brain / Sample_Type by Project: Shred V9

GBX1 DOK2 DMBX1 IRX4 MCTP2

2.16e-051431045eeb8ce6e051e18b82b74aaf2fc23f0cb87fc96d5
ToppCellPND01-03-samps-Myeloid-Macrophage-macrophage-B|PND01-03-samps / Age Group, Lineage, Cell class and subclass

RADX ARX LMNB2 BARHL1 ASPM

2.89e-0515210455ce8920aedd39a4daf7082153b5e213707c14227
ToppCell356C-Myeloid-Macrophage-FABP4+_Macrophage|356C / Donor, Lineage, Cell class and subclass (all cells)

OXCT2 ADCY6 ZNF711 PLA2G4C SPIDR

3.59e-05159104524f87c666eff10c1844c900ffd7ad49fa9f80481
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Calb2_Pdlim5|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

HTR1A SFRP2 ARX SSTR1 CDH4

3.70e-051601045dd16ca90feb3ae88b6409d6c278b4765da565514
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Calb2_Pdlim5|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

HTR1A SFRP2 ARX SSTR1 CDH4

3.81e-051611045bf70be1de418615b5442ec684552551edaf1f072
ToppCellPND10-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

TSGA13 SFRP2 LBP SULF1 TMEM117

4.54e-0516710457abc785e688a384672d7fb5a62d32538fe7e5a51
ToppCellPND10-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial-Mesothelial_mature|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

TSGA13 SFRP2 LBP SULF1 TMEM117

4.54e-051671045d50311b1f66f143bae4c4cf50e2e9b13c85d6920
ToppCellP28-Epithelial-epithelial_progenitor_cell|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

IRX5 SLC13A3 IRX3 IRX1 MYH14

4.67e-05168104503c95ad3684caec7a6d581006b237cc5fa230685
ToppCellPCW_10-12-Hematologic_ErythroMegGranulo-Hem_ErythroMeg-im_megakaryocyte2_(17)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

SPTB DOK2 RAB33A ADRA2A XIRP2

4.94e-0517010453886a77bc3ddbeb42a8149b759fe578871676d6e
ToppCellPND07-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1/AT2|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

IRX5 FOXO6 IRX3 IRX1 MYH14

5.36e-05173104545808cf69122c16b9d2b5ffa06d15392c55954b7
ToppCellPND07-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1/AT2-AT1/AT2_mature|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

IRX5 FOXO6 IRX3 IRX1 MYH14

5.36e-0517310457fa9dbcb258c3ab974490063951620e2def03db1
ToppCellPND03-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SFRP2 GBX1 SULF1 BARHL2 PALS2

5.36e-05173104530d67738633493d47f06ae452424382f069b6c0a
ToppCellPND03-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial-Mesothelial_mature|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SFRP2 GBX1 SULF1 BARHL2 PALS2

5.51e-051741045a9c6edf5c3fc119c24425f921c5566a8356c30fe
ToppCelldroplet-Lung-LUNG-30m-Endothelial-Artery_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SEMA3G SSTR1 SULF1 NCAN ATP2B2

6.30e-051791045a09647750eba9d93c5efc1db3b555fefb5eec7b5
ToppCellfacs-Lung-EPCAM-18m-Endothelial-endothelial_cell_of_lung|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RHBDF2 SEMA3G ALS2CL XIRP2 BARHL1

6.47e-051801045082c6116e0bbba8d9a3a82d14af55bdc8990c8c0
ToppCellfacs-Lung-EPCAM-18m-Endothelial-Capillary_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RHBDF2 SEMA3G ALS2CL XIRP2 BARHL1

6.47e-05180104553043d764fad9ac33ee40e356e562e759931adef
ToppCellfacs-Brain_Non-Myeloid-Cerebellum_-18m-Epithelial-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IRX5 LBP SULF1 ASPM PALS2

6.82e-051821045904804813849b7f7f716ba1554d33b07bc0a701e
ToppCelldroplet-Lung-nan-21m-Epithelial|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IRX5 IRX3 IRX1 MYH14 BARHL1

6.82e-05182104540539ade8c3cd12b61f1cd0d493828e58282796b
ToppCelldroplet-Lung-LUNG-1m-Epithelial-type_II_pneumocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FOXO6 IRX3 IRX1 MYH14 TMEM117

6.82e-051821045c1e0be27064e14043b78ae501b02d4e9542267a3
ToppCellfacs-Brain_Non-Myeloid-Cerebellum_-18m-Epithelial|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IRX5 LBP SULF1 ASPM PALS2

6.82e-0518210455d8b7fe18286e27f0f50c5d2d9be56850e2cb8f4
ToppCelldroplet-Lung-LUNG-1m-Epithelial-Alveolar_Epithelial_Type_2|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FOXO6 IRX3 IRX1 MYH14 TMEM117

6.82e-0518210453c9b4869d357884ae4bcd22a9872faf83a5cfc6d
ToppCelldroplet-Lung-30m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell-pulmonary_artery_endothelial_cell_l25|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SSTR1 SULF1 NCAN IL1R1 ATP2B2

7.00e-0518310456f8f997ffc9eaebca2683de125b6069d07c07d26
ToppCellPCW_05-06-Epithelial-Epithelial_airway-epi_proximal_progenitor1_(6)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

IRX5 IRX3 IRX1 MYH14 MCTP2

7.00e-051831045c5b10571599dc26476170b54b53f09c23e6b3117
ToppCelldroplet-Lung-30m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell-pulmonary_artery_endothelial_cell_l27|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

IRX3 SEMA3G ADCY6 MEST SULF1

7.00e-051831045351d575339038bd4a66f408da518c567444208e8
ToppCelldroplet-Lung-1m-Epithelial-alveolar_epithelial-type_II_pneumocyte-type_2_alveolar_epithelial_cell|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

FOXO6 IRX3 IRX1 MYH14 TMEM117

7.18e-05184104524cbe9f2461ea920954e44bf3b2c2a6a5d4debfb
ToppCelldroplet-Lung-1m-Epithelial-alveolar_epithelial-type_II_pneumocyte|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

FOXO6 IRX3 IRX1 MYH14 TMEM117

7.18e-05184104598079fd048a63b51bbdf3833b6f15bf0ae99ea90
ToppCell3'_v3-lymph-node_spleen-Hematopoietic_Erythro-Mega-Megakaryocyte_early|lymph-node_spleen / Manually curated celltypes from each tissue

MYLK SPTB PKD1L3 PLA2G4C MYH14

7.18e-05184104510607d7d92edcbb92d992900086b90b307421cc3
ToppCelldroplet-Lung-1m-Epithelial-alveolar_epithelial|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

FOXO6 IRX3 IRX1 MYH14 TMEM117

7.18e-05184104586c1551c4f7c7d0c35c14852b01b1e602fa5092a
ToppCellfacs-Brain_Non-Myeloid-Cerebellum_-18m-Neuronal|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GRIN1 PANX2 BARHL1 ATP2B2 ATP2B3

7.18e-0518410457d9bcdaff8cbea4c50ab7db0f8e01f6bbd0ef593
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-24m-Epithelial-Bergmann_glial_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SFRP2 IRX5 IRX1 SULF1 CDH4

7.18e-051841045f6148e9591e8845cc62668e49fd52755257cdc7e
ToppCellTCGA-Bladder-Primary_Tumor-Urothelial_Carcinoma-Non-Papillary_Muscle_Invasive_Urothelial_Carcinoma-4|TCGA-Bladder / Sample_Type by Project: Shred V9

SFRP2 MYLK ADRA2A SULF1 IL1R1

7.37e-051851045e1f3f0e974eb3fe1c05018beb9e124c7fb0cbe50
ToppCelldroplet-Lung-LUNG-1m-Endothelial-Artery_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SFRP2 ADCY6 ADRA2A SULF1 ATP2B2

7.56e-0518610451e67bfb248366d7395efdd2d5e70a97bdb2e68af
ToppCellfacs-Brain_Non-Myeloid-Striatum_-18m-Neuronal-interneuron|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SPTB GRIN1 IRX1 BARHL2 PALS2

7.56e-051861045a1ab273b01971d6a892912560d387685dd657179
ToppCellfacs-Brain_Non-Myeloid-Cerebellum_-18m-Neuronal-interneuron|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TSGA13 PANX2 BARHL2 ATP2B2 ATP2B3

7.75e-0518710451b2fdbfb1ce3f19795dfc4b1da5a94f4b057ec41
ToppCell10x5'v1-week_17-19-Hematopoietic|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

MYLK SPTB ADCY6 MEST XIRP2

7.95e-051881045c00ba0abd0c7bb2c8f9166a2ac6220aae4f4d857
ToppCellPCW_07-8.5-Epithelial-Epithelial_airway-epi_proximal_progenitor1_(6)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

IRX5 IRX3 IRX1 MYH14 MCTP2

8.15e-0518910457659c7bbd58ee959a159294fb8d17317bbcc5681
ToppCellBrain_organoid-organoid_Kanton_Nature-Organoid-2M-Radial_glial-RGCs_early_2|Organoid-2M / Sample Type, Dataset, Time_group, and Cell type.

SFRP2 IRX5 IRX3 IRX1 MEST

8.56e-05191104506107849463a1ccb78a5ccd3ae31619ef6bedda3
ToppCellfacs-Heart-LV-24m-Mesenchymal-ventricular_cardiomyocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SPTB IRX4 XIRP2 MYH14 TMEM117

8.56e-051911045543da1197c7e62f2c9cbd4a51414bbaaa6d1a92f
ToppCellPCW_05-06-Epithelial-Epithelial_neuroendo-epi_NE_progenitor_(7)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

IRX5 IRX3 IRX1 MYH14 MCTP2

8.56e-05191104505731ece7867659c662f952812805f947032fe10
ToppCellfacs-Heart-LV-24m-Mesenchymal-ventricular_myocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SPTB IRX4 XIRP2 MYH14 TMEM117

8.56e-0519110459d7d680da3979e256191b534ebd14c5383e0cf93
ToppCell10x5'v1-week_14-16-Hematopoietic-MK|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

MYLK ADCY6 RAB33A ADRA2A XIRP2

8.56e-0519110457edc22e7e70697fb22690699efb352577162709b
ToppCellPCW_05-06-Epithelial-Epithelial_neuroendo|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

IRX5 IRX3 IRX1 MYH14 MCTP2

8.99e-051931045aa10924b203c71e65fdbd2b90ba131dbd362d8b1
ToppCellPCW_13-14-Mesenchymal-Mesenchymal_fibroblastic-mes_adventitial_fibro_(10)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

IGFN1 SFRP2 ADAMTSL3 MEST SULF1

8.99e-051931045adc9fc94f9ec686a417d08c0b8b7b7ab687afec0
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Inner_Medullary_Collecting_Duct_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

POU5F1 ALS2CL ZNF440 MYH14 TMEM117

8.99e-051931045a5695ce2e24a62026ae28f3dea07ca4a435206b8
ToppCellPCW_05-06-Epithelial-Epithelial_alveolar-distal-epi_CTGF^high_distal_(3)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

IRX5 DRGX IRX3 IRX1 MYH14

9.21e-051941045c5ef4ff73b4e51530656002e3a2fb7264cdf533d
ToppCellPCW_07-8.5|World / Celltypes from embryonic and fetal-stage human lung

RPL31 SFRP2 SULF1 ASPM PALS2

9.21e-0519410455759c83308df017f1faae248e9b85388e25254f0
ToppCellPCW_07-8.5-Mesenchymal-Mesenchymal_fibroblastic-mes_immature_adventitial_fibro_(9)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

SFRP2 MYLK MEST SULF1 CDH4

9.21e-0519410455f5f0cdeacd5e1b28717d78dabdb9eb95f661e36
ToppCellPCW_05-06-Epithelial-Epithelial_airway-epi_proximal_secretory_(0)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

IRX5 IRX3 IRX1 MYH14 MCTP2

9.21e-051941045b19e16a76d7342ff9a665d19c9151652916f17d4
ToppCellPCW_07-8.5-Epithelial-Epithelial_airway|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

IRX5 IRX3 IRX1 MYH14 MCTP2

9.21e-051941045f95c8dc242c9aebcadfe61b1ed033349cb7e5a88
ToppCell5'-Adult-SmallIntestine-Epithelial-Tuft-related-BEST4+_epithelial|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SSTR1 ADRA2A MYH14 PALS2 TMEM117

9.44e-051951045e87b11e3242fdbed2e7f383e6876ec375af32bd4
ToppCell3'-Distal_airway-Epithelial-Epithelial_transtional-secretory-club_cell-Club_(non-nasal)-Club_(non-nasal)_L.0.4.0.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

RPL31 CYP2B6 ADRA2A MYH14 IL1R1

9.67e-0519610451ff4b41817556a6e573f0737819a5cc24a7ef821
ToppCell(1)_T_cells-(1)_T_CD8_CTL|(1)_T_cells / Spleen cell shreds - cell class (v1) and cell subclass (v1)

RHBDF2 STK38 DOK2 LILRB1 MCTP2

9.67e-051961045ad9b0651cb2a15b750e453b2dcf782bca08b4fe7
ToppCellPCW_05-06-Mesenchymal-Mesenchymal_fibroblastic-mes_immature1_(0)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

RPL31 SFRP2 MYLK MEST SULF1

9.67e-05196104522538376a95fe3afe8639a216a5497087aa94110
ToppCellkidney_cells-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Afferent_/_Efferent_Arteriole_Endothelial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SEMA3G SSTR1 SULF1 CRYBG3 STK38L

1.04e-0419910459b02acae6325b0ac9642438a4431285ff396e5fe
ToppCellBronchial-10x5prime-Stromal-Pericyte-Muscle_pericyte_systemic|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

MYLK SPTB ZNF711 ADRA2A ASPM

1.04e-04199104578a9b26215874a46a910a4b93a51fcac1a597618
ToppCellControl_saline-Epithelial_alveolar-AT_1-Differentiating_AT2|Control_saline / Treatment groups by lineage, cell group, cell type

SLC13A3 IRX3 IRX1 MEST MYH14

1.06e-042001045eac33be484dc443794e66e473f03e98406c2983e
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW10-Mesenchymal|GW10 / Sample Type, Dataset, Time_group, and Cell type.

DOK1 MYLK RHBDF2 SEMA3G RAB40A

1.06e-0420010455c638c80661017c85f9390f1b398ac7728c8f001
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW10-Mesenchymal-BMP_responsible_cell|GW10 / Sample Type, Dataset, Time_group, and Cell type.

DOK1 MYLK RHBDF2 SEMA3G RAB40A

1.06e-042001045604a88633d4162337e394155c7346dbdef8b9f5a
ToppCellLPS_only-Epithelial_alveolar-AT_2-AT1-AT2|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

IRX5 IRX3 IRX1 MYH14

1.38e-041121044456278fb92dd41820fde8cf27c68fec45e15f972
ToppCellSubstantia_nigra|World / BrainAtlas - Mouse McCarroll V32

IRX5 IRX3 IRX1 XIRP2

1.53e-04115104418174b8d57d444fab1e9d2b13d22939c83c958e0
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Nr2f2_Necab1|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

HTR1A SPTB ARX CDH4

2.04e-041241044298ff8bd8f0459f44ce8a8aea889c6f1cf84ac5f
ToppCellLPS-IL1RA+antiTNF-Epithelial_alveolar-AT_1-Differentiating_AT2|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

IRX5 IRX1 MYH14 FKTN

2.67e-0413310445bf5e654653e2c340891f51e3f2a30441b7b6b2b
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Tac1_Htr1d|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

SPTB ARX SSTR1 CDH4

3.16e-041391044fe1657ef9aeda7c530dc7febcd3dcd0e1d5f8a48
ToppCellfacs-Brain_Non-Myeloid-Hippocampus_-18m-Lymphocytic-T_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IRX5 IRX4 VILL MCTP2

3.42e-04142104458c2882cb0ede8cc5d84c85a650d28267268e748
ToppCellFrontal_cortex-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

SFRP2 SPTB ARX GBX1

3.71e-0414510448b13b576fd2e6e33ccb146860a91a53cee0cdd4d
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Degenerative_Cortical_Thick_Ascending_Limb_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

DOK1 SFRP2 RADX IRX3

3.90e-041471044f703cb0330304799d16e457215269c7732c9d5d5
ToppCellClub_cells-Donor_03|World / lung cells shred on cell class, cell subclass, sample id

CYP2B6 POU5F1B GRIN1 ADRA2A

3.90e-0414710445a824c89e4d045af465d7333275f8191fb29b041
ToppCellP15-Epithelial-epithelial_progenitor_cell-epithelial_progenitor_cell|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

IRX5 IRX3 IRX1 MYH14

3.90e-041471044aba44c7057096483c4293a7ebcf8ccc8baed0231
ToppCellThalamus-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)|Thalamus / BrainAtlas - Mouse McCarroll V32

HTR1A SFRP2 ARX SSTR1

4.00e-041481044afebb64365c94b9476494bffe7c364677f19c8cf
ToppCellThalamus-Neuronal-Inhibitory|Thalamus / BrainAtlas - Mouse McCarroll V32

HTR1A SFRP2 ARX SSTR1

4.00e-0414810445f82e5ecacfd223020b8ee975c17d68c1fe6db38
ToppCellPericytes-IPF_04|World / lung cells shred on cell class, cell subclass, sample id

MYLK ADAMTSL3 ARVCF SULF1

4.21e-041501044dbc202bd6db4fb5c8b2abd1200e074a2a9e63a59
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Rxfp1_Prdm8|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

HTR1A SFRP2 ARX SSTR1

4.32e-041511044090b067873740c282865e2d02cf47d5cb3dd7607
ToppCellPND14-Immune-Immune_Myeloid-DC-cDC2-cDC2_mature|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SLC13A3 LILRB1 ADRA2A PALS2

4.43e-041521044b2e29fbda6b5f2d87cfc05423caf9cbf3b04ac65
ToppCellP15-Epithelial-epithelial_progenitor_cell|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

IRX5 IRX3 IRX1 MYH14

4.43e-04152104400d5503d462cfa009fb4cac79ecee11725a18b9a
ToppCellsaliva-Severe-critical_progression_d12-22_with-steroid-Myeloid-Granulocytic-Neutrophil-Neu_c6-FGF23|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

TSGA13 POR PANX2 DMBX1

4.54e-0415310448bc09b8b1a32a8d7ac8201c626d2b306e7cc2972
ToppCellfacs-Spleen-nan-24m-Lymphocytic-NK_cell|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

POGK RADX GRIN1 DOK2

4.65e-041541044bd283c2367afb99294e7576a0c0167eb7c69ad6b
ToppCellBrain_organoid-organoid_Kanton_Nature-Organoid-4M-Neuronal-midbrain/hindbrain_cells|Organoid-4M / Sample Type, Dataset, Time_group, and Cell type.

IRX5 IRX3 IRX4 BARHL2

4.65e-041541044df1b58a20af73fa79c6c069c0117a9ffd85b476f
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Renal_corpuscle_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

IGFN1 ALS2CL SULF1 PURG

4.77e-04155104490e629681a72baacc7981b82883866a487638dbc
ToppCellP28-Epithelial-epithelial_progenitor_cell-epi_progenitor|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

SLC13A3 IRX3 IRX1 MYH14

4.77e-041551044be575a0096415705dba425002247289ff8f89474
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Hpse_Sema3c|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

HTR1A SFRP2 ARX MCTP2

4.77e-0415510445c7b68b59244525e3714806c205a57a2daebf423
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

SFRP2 RAB40A SULF1 STK38L

4.88e-041561044d5207dbfbcfb885557ea1378dfe6a56d7102e94a
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast-|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

SFRP2 RAB40A SULF1 STK38L

4.88e-041561044363f1b661048d25895e2b8681c82894c957b29c0
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Degenerative_Cortical_Thick_Ascending_Limb_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

FOXO6 IRX1 MRPL2 ATP2B3

5.12e-0415810445590fd7d7833685abd9bb86ef704c7f879b3ddbd
ToppCellmild_COVID-19_(asymptomatic)-B_cell|World / disease group, cell group and cell class (v2)

TSGA13 MYLK SPTB IRX3

5.12e-041581044afa8fa21c39c2192c1e23a4660011d63d58b733f
ToppCell367C-Lymphocytic-CD4_T-cell-Treg_cell_1|CD4_T-cell / Donor, Lineage, Cell class and subclass (all cells)

DOK1 SEMA3G PKD1L3 THRA

5.25e-041591044ae53ab7a1339007d0b245c6c291ac61e5ff5b682
ToppCell367C-Lymphocytic-CD4_T-cell-Treg_cell_1|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

DOK1 SEMA3G PKD1L3 THRA

5.25e-041591044b05fda31b77536a1878f55d3199563b53f9420b2
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

IGFN1 MTMR11 ATP2B2 PURG

5.25e-0415910449f6607e395bcca9cb1c83199bdbbaaa62a93938d
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell-Parietal_Epithelial_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

IGFN1 MTMR11 ATP2B2 PURG

5.25e-041591044c8b42ebc25ebcc450832096fbffaa5c5f5fe88e7
ToppCell390C-Epithelial_cells-Epithelial-A_(AT2)|390C / Donor, Lineage, Cell class and subclass (all cells)

IRX3 PLA2G4C MYH14 CRYBG3

5.37e-041601044731def6d82814ebac1a400bc7aea5f6da43ec960
DrugPropoxycaine hydrochloride [550-83-4]; Up 200; 12uM; MCF7; HT_HG-U133A

DOK1 HTR1A COPA SRCAP ALS2CL NCAN STK38L ATP2B2

3.21e-0619710386803_UP
DrugPF-00562151-00 [351320-12-2]; Down 200; 10uM; MCF7; HT_HG-U133A

SPTB GRIN1 EPX ALS2CL THRA PLA2G4C ARVCF ATP2B3

3.46e-0619910385954_DN
Drugvitamin D3

CYP2B6 IRX5 POR ADCY6 THRA KAT6B IL1R1 ATP2B2 ATP2B3

4.74e-062771039CID000002735
Drugisoxaben

IRX5 ARX IRX3 IRX1

1.13e-05311034CID000073672
DiseaseHailey-Hailey disease (implicated_via_orthology)

ATP2B2 ATP2B3

1.69e-0461002DOID:0050429 (implicated_via_orthology)
DiseaseRaynaud disease

IRX1 ADRA2A

1.69e-0461002EFO_1001145
Diseasehigh grade glioma (is_marker_for)

MTOR BARHL1 ASPM

3.94e-04421003DOID:3070 (is_marker_for)
DiseaseSchizophrenia

HTR1A ADAMTSL3 ALS2CL LILRB1 ADRA2A PLA2G4C ARVCF MTOR NCAN MCTP2

8.36e-0488310010C0036341
DiseaseMalignant neoplasm of breast

RPL31 SFRP2 ERCC6 PANX2 ALS2CL FKTN MTOR MACF1 UTP20 KAT6B PURG

1.04e-03107410011C0006142
Diseaseovarian neoplasm

DOK1 ERCC6 MTOR SULF1

1.14e-031341004C0919267
DiseaseMalignant neoplasm of ovary

DOK1 ERCC6 MTOR SULF1

1.24e-031371004C1140680
Diseasegliosarcoma

CYP2B6 POR

1.32e-03161002C0206726
Diseaseprimary autosomal recessive microcephaly (is_implicated_in)

LMNB2 ASPM

1.32e-03161002DOID:0070296 (is_implicated_in)
DiseaseBladder Neoplasm

POR FBXW8 MTOR NCAN

1.34e-031401004C0005695
DiseaseMalignant neoplasm of urinary bladder

POR FBXW8 MTOR NCAN

1.37e-031411004C0005684
Diseaseschizophrenia, inflammatory bowel disease

IRF3 EPX

1.68e-03181002EFO_0003767, MONDO_0005090
DiseaseLung diseases

IRX5 IRX3 IRX1

2.39e-03781003C0024115
DiseaseAutosomal Recessive Primary Microcephaly

COPB2 ASPM

2.51e-03221002C3711387
Diseaseanxiety disorder (implicated_via_orthology)

HTR1A ADRA2A

2.51e-03221002DOID:2030 (implicated_via_orthology)

Protein segments in the cluster

PeptideGeneStartEntry
GRKRRWGASTATTQK

ACIN1

846

Q9UKV3
IDSKCRTAWRRKQRG

BANP

311

Q8N9N5
QKAAKRRSEYWRGQR

ALS2CL

116

Q60I27
KNVVGARRSSWRVIS

YWHAB

51

P31946
ANGNRWKVLRRFSVT

CYP2B6

116

P20813
RGTLQKDGWTKARFQ

ARVCF

836

O00192
FRQKWRLNKNGTISS

CRYBG3

2916

Q68DQ2
KTAWGERNGQKRSRR

ADCY6

16

O43306
RAAKFVARKNWVVTG

COPB2

61

P35606
YQNRRTKWKRQTAVG

BARHL1

226

Q9BZE3
LWKRGRDNGQFLSRK

ADAP1

136

O75689
DTQARERAWRIGQKK

ERCC6

941

Q03468
LQSAYRGWKVRKQIR

ASPM

1881

Q8IZT6
SMWKGKTLRRQLQRQ

ASPM

1956

Q8IZT6
NDWSKEKQFRGLQSR

ATP2B2

171

Q01814
WSKEKQFRGLQSRIE

ATP2B3

176

Q16720
KVQVWDTAGQERFRK

RAB33A

86

Q14088
QRVKLKLWDTSGQGR

RAB40A

61

Q8WXH6
QRVKLKLWDTSGQGR

RAB40AL

61

P0C0E4
TWFANARRRLKKENK

IRX4

191

P78413
STWFANARRRLKKEN

IRX5

161

P78411
GTKRGLSKWRQNKER

KAT6B

1251

Q8WYB5
ANLQGKARKTISDRW

RADX

666

Q6NSI4
DVVRVWFCNRRQKGK

POU5F1B

271

Q06416
WFCNRRQKGKRSSSD

POU5F1B

276

Q06416
GDSKERVRWRTKQNL

MGAT4A

226

Q9UM21
WAVLRINSAKGRRKA

OR2H2

221

O95918
QQTFGKKWRRFGASL

DOK2

16

O60496
SDSSIRVQGRWKVRK

LBP

106

P18428
ARRKWQKTGNAVRAI

MYLK

1741

Q15746
KQGDFKRHRWSNRKR

MCTP2

316

Q6DN12
KAGRINKGVATNWLR

POR

481

P16435
FSRAKKANKRGDWRD

NEIL2

146

Q969S2
RKKQAARGWRVSTVN

MTMR11

206

A4FU01
NSDKDQSLGNWRIKR

LMNB2

491

Q03252
TGKTRRKGLANVQWS

ARMC9

631

Q7Z3E5
RNKRGGRWLVSLAKQ

EIF4E1B

131

A6NMX2
NGTTKWQTVRRQKRE

DSG4

36

Q86SJ6
LRTNWKNRKGAVSEL

FBXW8

191

Q8N3Y1
QARRGKGAWEKTRLA

MYH14

1231

Q7Z406
ASFRRKQPQEAAVWR

PCYOX1L

381

Q8NBM8
YNWTQKSIKQRLRSG

EPX

51

P11678
PLRKAKSSRRNAWGN

FOXO6

76

A8MYZ6
NAERKDNVNRRSWKS

MACF1

121

O94854
AKQFGVLEKNVRDWR

POGK

221

Q9P215
VWRRNARAKAKANAR

H1-7

171

Q75WM6
KDVVRVWFCNRRQKG

POU5F1

271

Q01860
VWFCNRRQKGKRSSS

POU5F1

276

Q01860
EKRKAFVRRDWDNSG

PALS2

281

Q9NZW5
TLKGLWRRAVANAKS

PLA2G4C

261

Q9UP65
NRRAKWKRIKAGNVS

GBX1

311

Q14549
FLQSQRFGTKRWRKT

DOK1

11

Q99704
QLSAKTWRRGLRLQK

PIK3CD-AS1

36

Q5SR53
PEARVQVWFKNRRAK

DMBX1

111

Q8NFW5
KRSSGLTAVWVARNR

COPA

411

P53621
AAVRKNWTITRLNGD

CDH4

656

P55283
KKSVNGESGSRNWRL

HTR1A

251

P08908
QNRRTKWKRQTAVGL

BARHL2

281

Q9NY43
SRIGFDSTQWRAVKK

FKTN

46

O75072
FQNRRAKWRKTERGA

DRGX

81

A6NNA5
FQNRRAKWRKREKAG

ARX

376

Q96QS3
KRSLVQRRKQLGWFT

FTCDNL1

96

E5RQL4
ERRKKGSNTWTAVND

IGFN1

781

Q86VF2
FRGWRKNKSEIRTNA

SLC13A3

306

Q8WWT9
QGPQSAKTRFWKNVR

IL1R1

521

P14778
NQRKKFRRRWVGALA

MEST

256

Q5EB52
VWASKTNLEQRKGRA

DHX9

751

Q08211
HKVGIKTRRQWRRSQ

PANX2

326

Q96RD6
WIGRGRQDNIRKSKL

PURG

91

Q9UJV8
TWFANARRRLKKENK

IRX3

176

P78415
WKRNFRSALNRKEGL

IRF3

76

Q14653
STINLQKAWGAARRV

MTOR

1261

P42345
WKTLRAAFQASKRNG

TSGA10IP

341

Q3SY00
TWFGAKKRLNRQLAA

UTP20

2371

O75691
RVQGVFQRASAKWKD

UTP6

91

Q9NYH9
TSVKRWQKGQREFKR

SFRP2

271

Q96HF1
WQKGQREFKRISRSI

SFRP2

276

Q96HF1
KAGWQQRKRSERKIT

SSTR1

256

P30872
WKRNRRQLAFSTVGT

STK38

271

Q15208
TWKKNRRQLAYSTVG

STK38L

271

Q9Y2H1
RRQGKHWTSTQRKAD

LILRB1

486

Q8NHL6
TWFANARRRLKKENK

IRX1

176

P78414
AKDNVVRVAKSWQGR

NCAN

96

O14594
QKWRFFTGKRNILDT

PKD1L3

1491

Q7Z443
FAQERRWKRGVARKV

SRCAP

151

Q6ZRS2
ARKQKAREAAAGIQW

NOP2

166

P46087
KGWKADRAGNVVFRR

OXCT2

211

Q9BYC2
AAKASRWRGRQNREK

ADRA2A

371

P08913
VRKNFQKTWQESGRV

XIRP2

3301

A4UGR9
SAFRNGRAPQWIIKK

TSGA13

256

Q96PP4
TFRNLTSLGKRWKDQ

ZNF440

36

Q8IYI8
TRLNKAVWAKGIRNV

RPL31

66

P62899
RARGSKRKRSWNTEC

SPIDR

6

Q14159
DHNKRVIGKAGRNRW

MRPL2

251

Q5T653
AAGRKAQLEQSKRLW

SPTB

626

P11277
KKSRQAWLTARGFQV

nan

471

Q6ZUG5
KNSTAVWRGRDSRKE

POGLUT2

301

Q6UW63
TWSEKRRRNQKLGGR

VILL

346

O15195
VWISKASAIQRKGRA

YTHDC2

726

Q9H6S0
FRSRSRGKQARGKSW

SEMA3G

741

Q9NS98
RSTNAQGSHWKQRRK

THRA

176

P10827
KSARAFWKKGNVRIT

TMEM117

186

Q9H0C3
AKKRRRGETRQWQTA

ZNF711

356

Q9Y462
GFQNRRLKKSQPRTW

RHBDF2

51

Q6PJF5
NRFRTNKKAKIWRDT

SULF1

396

Q8IWU6
DFPSKKRKRSRWNQD

SF1

11

Q15637
VRRFQKSLIQWEKDG

ADAMTSL3

936

P82987
RTGQEVQKRWNDFKR

MYPOP

71

Q86VE0
NVWRKNLQDRKSGRA

GRIN1

856

Q05586