Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
MousePhenoabnormal forebrain morphology

CHL1 PIK3R4 GHRHR OR8A1 ROBO4 MICAL1 ATR RNF19A PAFAH1B1 APC2 APAF1 APC ARHGAP11A DISP1 ARSG PCNT

2.81e-0510726616MP:0000783
MousePhenoabnormal nose morphology

CHL1 TBX15 OR8A1 ATR APAF1 ETV5 DISP1

4.35e-05201667MP:0002233
MousePhenoabnormal hippocampus stratum oriens morphology

PIK3R4 PAFAH1B1

6.57e-053662MP:0011150
MousePhenoabnormal limbic system morphology

CHL1 PIK3R4 MICAL1 RNF19A PAFAH1B1 APC2 APAF1 ARSG PCNT

6.66e-05378669MP:0004166
MousePhenoabnormal telencephalon morphology

CHL1 PIK3R4 OR8A1 ROBO4 MICAL1 ATR RNF19A PAFAH1B1 APC2 APAF1 ARHGAP11A ARSG PCNT

9.04e-058126613MP:0000787
MousePhenoabnormal cerebral hemisphere morphology

CHL1 PIK3R4 MICAL1 ATR RNF19A PAFAH1B1 APC2 APAF1 ARHGAP11A ARSG PCNT

1.02e-045996611MP:0008540
MousePhenoabnormal hippocampus morphology

CHL1 PIK3R4 MICAL1 RNF19A PAFAH1B1 APC2 ARSG PCNT

1.58e-04331668MP:0000807
MousePhenoabnormal temporal lobe morphology

CHL1 PIK3R4 MICAL1 RNF19A PAFAH1B1 APC2 ARSG PCNT

1.78e-04337668MP:0000801
MousePhenoabsent gametes

ATR PAFAH1B1 APAF1 FBXO43 LMTK2 ETV5 TRIM37

1.97e-04256667MP:0001117
MousePhenoabnormal head shape

TBX15 ATR APAF1 DISP1 PCNT

2.07e-04115665MP:0011495
MousePhenoabnormal telencephalon development

ROBO4 PAFAH1B1 APAF1 ARHGAP11A PCNT

3.16e-04126665MP:0000934
DomainAPC_dom

APC2 APC

2.00e-052842IPR026831
DomainAPC_N

APC2 APC

2.00e-052842IPR032038
DomainAPC_basic_dom

APC2 APC

2.00e-052842IPR009234
DomainApc_fam

APC2 APC

2.00e-052842IPR026818
DomainAPC_r

APC2 APC

2.00e-052842PF05923
DomainSAMP

APC2 APC

2.00e-052842PF05924
DomainAPC_rpt

APC2 APC

2.00e-052842IPR009223
DomainSAMP

APC2 APC

2.00e-052842IPR009224
DomainAPC_basic

APC2 APC

2.00e-052842PF05956
DomainAPC_N_CC

APC2 APC

2.00e-052842PF16689
DomainSPAR_C

SIPA1L1 SIPA1L2

5.98e-053842PF11881
DomainSIPA1L_C

SIPA1L1 SIPA1L2

5.98e-053842IPR021818
DomainSpectrin/alpha-actinin

AKAP6 DRP2 MCF2L2

3.96e-0432843IPR018159
DomainSPEC

AKAP6 DRP2 MCF2L2

3.96e-0432843SM00150
DomainPDZ

SIPA1L1 FRMPD1 SIPA1L2 SHROOM2 TIAM2

4.37e-04141845PF00595
DomainPDZ

SIPA1L1 FRMPD1 SIPA1L2 SHROOM2 TIAM2

5.45e-04148845SM00228
Domain-

SIPA1L1 FRMPD1 SIPA1L2 SHROOM2 TIAM2

5.79e-041508452.30.42.10
DomainPDZ

SIPA1L1 FRMPD1 SIPA1L2 SHROOM2 TIAM2

5.97e-04151845PS50106
DomainPDZ

SIPA1L1 FRMPD1 SIPA1L2 SHROOM2 TIAM2

6.15e-04152845IPR001478
Domainfn3

CHL1 NPHS1 ROBO4 PTPRB USH2A

8.21e-04162845PF00041
DomainWD40_repeat_CS

PIK3R4 AAMP WDR88 PAFAH1B1 APAF1

8.67e-04164845IPR019775
DomainRap_GAP

SIPA1L1 SIPA1L2

8.79e-0410842PF02145
DomainRap_GAP_dom

SIPA1L1 SIPA1L2

1.07e-0311842IPR000331
DomainRAPGAP

SIPA1L1 SIPA1L2

1.07e-0311842PS50085
DomainHEAT

PIK3R4 NCAPD3 ATR

1.31e-0348843PF02985
DomainFN3

CHL1 NPHS1 ROBO4 PTPRB USH2A

1.48e-03185845SM00060
DomainIBR

RNF19A FBXO43

1.76e-0314842SM00647
DomainIBR

RNF19A FBXO43

1.76e-0314842PF01485
DomainIBR_dom

RNF19A FBXO43

2.02e-0315842IPR002867
DomainFN3

CHL1 NPHS1 ROBO4 PTPRB USH2A

2.04e-03199845PS50853
DomainHEAT

PIK3R4 NCAPD3 ATR

2.27e-0358843IPR000357
DomainFN3_dom

CHL1 NPHS1 ROBO4 PTPRB USH2A

2.52e-03209845IPR003961
DomainHEAT_type_2

PIK3R4 ATR

2.60e-0317842IPR021133
DomainSulfatase

PIGG ARSG

2.92e-0318842PF00884
DomainSulfatase_N

PIGG ARSG

2.92e-0318842IPR000917
Domain-

PIK3R4 NCAPD3 ATR APC2 APC

3.27e-032228451.25.10.10
DomainHEAT_REPEAT

PIK3R4 NCAPD3 ATR

3.87e-0370843PS50077
Domain-

PIK3R4 AAMP WDR88 PAFAH1B1 APAF1 BIRC6

3.89e-033338462.130.10.10
DomainWD40/YVTN_repeat-like_dom

PIK3R4 AAMP WDR88 PAFAH1B1 APAF1 BIRC6

4.01e-03335846IPR015943
DomainTRAF-like

FBXO40 TRIM37

5.17e-0324842IPR008974
Pubmed

Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.

AKAP6 PASK SIPA1L1 CHD5 APAF1 BIRC6 BAIAP3 PCNT

1.02e-0722587812168954
Pubmed

Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.

AKAP6 PIK3R4 ZBTB38 SIPA1L1 SH3D19 APC2 SERGEF MCF2L2 APC CABIN1 SHROOM2 ABHD12 TRIM37 TXNDC11 USP47 PCNT

1.10e-071285871635914814
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

ZFYVE16 STARD9 SIPA1L1 FRMPD1 MLXIP SIPA1L2 BAIAP3 RUBCN PCNT

8.64e-0740787912693553
Pubmed

Functional redundancy between Apc and Apc2 regulates tissue homeostasis and prevents tumorigenesis in murine mammary epithelium.

APC2 APC

6.19e-06287227694902
Pubmed

APC2 is critical for ovarian WNT signalling control, fertility and tumour suppression.

APC2 APC

6.19e-06287231291912
Pubmed

Genetic enhancement of the Lis1+/- phenotype by a heterozygous mutation in the adenomatous polyposis coli gene.

PAFAH1B1 APC

6.19e-06287218075263
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

AKAP6 PASK NCAPD3 CHD5 MED12L LMTK2 ARHGAP11A ANKS3 TIAM2

7.30e-0652987914621295
Pubmed

The deubiquitinase TRABID stabilizes the K29/K48-specific E3 ubiquitin ligase HECTD1.

PIK3R4 RABEP2 NCAPD3 SIPA1L1 USP47 PCNT

1.60e-0521287633853758
Pubmed

A three-gene expression signature model for risk stratification of patients with neuroblastoma.

CHD5 PAFAH1B1

1.85e-05387222328561
Pubmed

RapGAPs in brain: multipurpose players in neuronal Rap signalling.

SIPA1L1 SIPA1L2

1.85e-05387220576033
Pubmed

Functional comparison of human adenomatous polyposis coli (APC) and APC-like in targeting beta-catenin for degradation.

APC2 APC

1.85e-05387223840886
Pubmed

Expanding the clinical phenotype in patients with disease causing variants associated with atypical Usher syndrome.

ABHD12 ARSG

3.70e-05487234223797
Pubmed

Neuroepithelial stem cell proliferation requires LIS1 for precise spindle orientation and symmetric division.

PAFAH1B1 PCNT

3.70e-05487218267077
Pubmed

A novel GSK3-regulated APC:Axin interaction regulates Wnt signaling by driving a catalytic cycle of efficient βcatenin destruction.

APC2 APC

3.70e-05487226393419
Pubmed

Evidence that an interaction between EB1 and p150(Glued) is required for the formation and maintenance of a radial microtubule array anchored at the centrosome.

PIK3R4 APC

6.16e-05587212388762
Pubmed

Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.

AKAP6 SLC17A9 SIPA1L1 FRMPD1 APC LMTK2 SHROOM2 BAIAP3 TRIM37 TIAM2 PCNT

8.25e-051084871111544199
Pubmed

The F-box protein beta-TrCP associates with phosphorylated beta-catenin and regulates its activity in the cell.

APC2 APC

9.22e-05687210074433
Pubmed

Regulation of Beclin 1 in autophagy.

PIK3R4 RUBCN

9.22e-05687219372752
Pubmed

The RUN domain of rubicon is important for hVps34 binding, lipid kinase inhibition, and autophagy suppression.

PIK3R4 RUBCN

9.22e-05687221062745
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

CHD5 LMTK2 PIGG ZNF579 MLXIP SIPA1L2 CABIN1 BIRC6 ARSG TIAM2 PCNT

9.78e-051105871135748872
Pubmed

Prediction of the coding sequences of unidentified human genes. XII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.

NUP210 MCF2L2 MLXIP TRIM37

1.19e-0410087410048485
Pubmed

Distinct regulation of autophagic activity by Atg14L and Rubicon associated with Beclin 1-phosphatidylinositol-3-kinase complex.

PIK3R4 RUBCN

1.29e-04787219270693
Pubmed

Two Beclin 1-binding proteins, Atg14L and Rubicon, reciprocally regulate autophagy at different stages.

PIK3R4 RUBCN

1.29e-04787219270696
Pubmed

Domains of axin involved in protein-protein interactions, Wnt pathway inhibition, and intracellular localization.

APC2 APC

1.29e-04787210330403
Pubmed

Oncogenic PIK3CA induces centrosome amplification and tolerance to genome doubling.

APC PCNT

1.72e-04887229170395
Pubmed

Phosphoproteome analysis of the human mitotic spindle.

NCAPD3 NUP210 ARHGAP11A KNL1 PCNT

1.89e-0421087516565220
Pubmed

Downregulation of beta-catenin by human Axin and its association with the APC tumor suppressor, beta-catenin and GSK3 beta.

APC2 APC

2.20e-0498729601641
Pubmed

Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.

PIK3R4 DIP2B FREM2 NCAPD3 ATR NOA1 APC RUBCN

2.28e-0465087838777146
Pubmed

HENA, heterogeneous network-based data set for Alzheimer's disease.

MICAL1 PAFAH1B1 APC TRIM37

2.41e-0412087431413325
Pubmed

A conserved acetylation switch enables pharmacological control of tubby-like protein stability.

DIP2B AAMP TUBD1 BIRC6 USP47

2.50e-0422387533187986
Pubmed

STYK1 promotes autophagy through enhancing the assembly of autophagy-specific class III phosphatidylinositol 3-kinase complex I.

PIK3R4 RUBCN

2.75e-041087231696776
Pubmed

A systems-wide screen identifies substrates of the SCFβTrCP ubiquitin ligase.

SIPA1L1 APC SIPA1L2 USP47 KNL1

3.00e-0423287525515538
Pubmed

Identification of motif-based interactions between SARS-CoV-2 protein domains and human peptide ligands pinpoint antiviral targets.

FBXO40 STARD9 PCDH11Y ETV5 SHROOM2

3.06e-0423387537704626
Pubmed

Prediction of the coding sequences of unidentified human genes. VIII. 78 new cDNA clones from brain which code for large proteins in vitro.

SIPA1L1 APAF1 PCNT

3.06e-04528739455477
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

PIK3R4 DIP2B STARD9 SIPA1L1 SH3D19 APC LMTK2 MLXIP SIPA1L2

3.07e-0486187936931259
Pubmed

Whole exome sequencing identifies novel recurrently mutated genes in patients with splenic marginal zone lymphoma.

PLA2G4D USH2A

3.35e-041187224349473
Pubmed

Control of oligodendrocyte generation and proliferation by Shp2 protein tyrosine phosphatase.

MNX1 APC

3.35e-041187220648636
Pubmed

The adenomatous polyposis coli protein is an essential regulator of radial glial polarity and construction of the cerebral cortex.

APC PCNT

3.35e-041187219146812
Pubmed

LIS1 regulates CNS lamination by interacting with mNudE, a central component of the centrosome.

PAFAH1B1 PCNT

3.35e-041187211163258
Pubmed

Mouse Disp1 is required in sonic hedgehog-expressing cells for paracrine activity of the cholesterol-modified ligand.

MNX1 DISP1

4.02e-041287215576405
Pubmed

Association between genes of Disrupted in schizophrenia 1 (DISC1) interactors and schizophrenia supports the role of the DISC1 pathway in the etiology of major mental illnesses.

PAFAH1B1 PCNT

4.02e-041287219251251
Pubmed

Intrinsic neural stem cell properties define brain hypersensitivity to genotoxic stress.

ATR PCNT

4.02e-041287235623353
Pubmed

The intracellular redox protein MICAL-1 regulates the development of hippocampal mossy fibre connections.

CHL1 MICAL1

4.02e-041287225007825
Pubmed

Apaf1-deficient cortical neurons exhibit defects in axonal outgrowth.

APAF1 PCNT

4.02e-041287225975226
Pubmed

Novel embryonic neuronal migration and proliferation defects in Dcx mutant mice are exacerbated by Lis1 reduction.

PAFAH1B1 PCNT

4.02e-041287220181597
Pubmed

WT1 targets Gas1 to maintain nephron progenitor cells by modulating FGF signals.

NPHS1 ETV5

4.02e-041287225804736
Pubmed

Endofin is required for HD-PTP and ESCRT-0 interdependent endosomal sorting of ubiquitinated transmembrane cargoes.

ZFYVE16 SH3D19 BIRC6

4.67e-046087334761192
Pubmed

mTORC1 phosphorylates UVRAG to negatively regulate autophagosome and endosome maturation.

PIK3R4 RUBCN

4.74e-041387225533187
Pubmed

Maturation of the olfactory sensory neurons by Apaf-1/caspase-9-mediated caspase activity.

OR8A1 APAF1

4.74e-041387220624980
Pubmed

CHD5 is required for neurogenesis and has a dual role in facilitating gene expression and polycomb gene repression.

CHD5 APC

4.74e-041387223948251
Pubmed

The DNA sequence, annotation and analysis of human chromosome 3.

ZBTB38 NUP210 RUBCN

5.14e-046287316641997
Pubmed

Gene-specific requirement for P-TEFb activity and RNA polymerase II phosphorylation within the p53 transcriptional program.

APC2 APC

6.36e-041587216510875
Pubmed

ETS transcription factor Erm controls subsynaptic gene expression in skeletal muscles.

MNX1 ETV5

6.36e-041587217785180
Pubmed

Defining the membrane proteome of NK cells.

PIK3R4 DIP2B NCAPD3 GLT8D1 MAN2A1 CHD5 NUP210 PIGG BIRC6 PCNT

6.75e-041168871019946888
Pubmed

Local apoptosis modulates early mammalian brain development through the elimination of morphogen-producing cells.

APAF1 ETV5

7.26e-041687224369835
Pubmed

Primary Autosomal Recessive Microcephalies and Seckel Syndrome Spectrum Disorders – RETIRED CHAPTER, FOR HISTORICAL REFERENCE ONLY

ATR KNL1

7.26e-041687220301772
Pubmed

The Transcriptional Activator Krüppel-like Factor-6 Is Required for CNS Myelination.

MNX1 APC

7.26e-041687227213272
Pubmed

A Human Tyrosine Phosphatase Interactome Mapped by Proteomic Profiling.

DIP2B PASK NCAPD3 ZFYVE16 NUP210 TTC13 SIPA1L2 ABHD12 USP47

7.44e-0497487928675297
Pubmed

Ex vivo Quantitative Proteomic Analysis of Serotonin Transporter Interactome: Network Impact of the SERT Ala56 Coding Variant.

STARD9 SIPA1L1 APC2 FRMPD1 APC SIPA1L2

7.49e-0443087632581705
Pubmed

Virus-Host Interactome and Proteomic Survey Reveal Potential Virulence Factors Influencing SARS-CoV-2 Pathogenesis.

GLT8D1 ATR TTC13 TXNDC11 PCNT

7.62e-0428587532838362
Pubmed

Lis1-Nde1-dependent neuronal fate control determines cerebral cortical size and lamination.

PAFAH1B1 PCNT

9.22e-041887218469343
Pubmed

HDAC1 and HDAC2 regulate oligodendrocyte differentiation by disrupting the beta-catenin-TCF interaction.

MNX1 APC

9.22e-041887219503085
Pubmed

TGF-β signaling and Creb5 cooperatively regulate Fgf18 to control pharyngeal muscle development.

TBX15 ETV5

1.14e-032087236542062
Pubmed

Differential regulation of microtubule severing by APC underlies distinct patterns of projection neuron and interneuron migration.

APC2 APC

1.14e-032087225535916
Pubmed

Protein kinase A acts at the basal body of the primary cilium to prevent Gli2 activation and ventralization of the mouse neural tube.

MNX1 PCNT

1.26e-032187222007132
Pubmed

Programmed cell senescence during mammalian embryonic development.

ATR PCNT

1.26e-032187224238962
Pubmed

Peptidic degron in EID1 is recognized by an SCF E3 ligase complex containing the orphan F-box protein FBXO21.

DISP1 PCNT

1.38e-032287226631746
Pubmed

Major β cell-specific functions of NKX2.2 are mediated via the NK2-specific domain.

MNX1 APC

1.38e-032287237364986
Pubmed

Common developmental requirement for Olig function indicates a motor neuron/oligodendrocyte connection.

MNX1 APC

1.38e-032287211955448
Pubmed

Homozygous Ft embryos are affected in floor plate maintenance and ventral neural tube patterning.

MNX1 IRX2

1.38e-032287215789444
Pubmed

Maternal genes and facial clefts in offspring: a comprehensive search for genetic associations in two population-based cleft studies from Scandinavia.

CHL1 TBX15 ATR PAFAH1B1 ETV5

1.48e-0333187520634891
Pubmed

Systematically defining selective autophagy receptor-specific cargo using autophagosome content profiling.

GLT8D1 MAN2A1 ZFYVE16 NOA1 PAFAH1B1 NUP210 APC TTC13 PIGG BIRC6

1.49e-031297871033545068
Pubmed

Fras1, a basement membrane-associated protein mutated in Fraser syndrome, mediates both the initiation of the mammalian kidney and the integrity of renal glomeruli.

NPHS1 FREM2

1.51e-032387218787044
Pubmed

mTOR drives its own activation via SCF(βTrCP)-dependent degradation of the mTOR inhibitor DEPTOR.

SIPA1L1 USP47

1.51e-032387222017875
Pubmed

Combinatorial actions of Tgfβ and Activin ligands promote oligodendrocyte development and CNS myelination.

MNX1 APC

1.51e-032387224917498
Pubmed

Functional Characterization of DNA Methylation in the Oligodendrocyte Lineage.

MNX1 APC

1.65e-032487227149841
Pubmed

Effect of N-(3-phenyl-2-propenyl)-1-deoxynojirimycin on the lectin binding to HIV-1 glycoproteins.

GLT8D1 MAN2A1

1.79e-03258722283726
Pubmed

Adenomatous polyposis coli is required for early events in the normal growth and differentiation of the developing cerebral cortex.

APC PCNT

1.79e-032587219149881
Pubmed

A MicroRNA Profile in Fmr1 Knockout Mice Reveals MicroRNA Expression Alterations with Possible Roles in Fragile X Syndrome.

CHL1 PAFAH1B1

1.79e-032587224906954
Pubmed

Interactomes of Glycogen Synthase Kinase-3 Isoforms.

PASK SIPA1L1 APC SIPA1L2

1.91e-0320987436779422
Pubmed

Epidermal development requires ninein for spindle orientation and cortical microtubule organization.

PAFAH1B1 PCNT

1.93e-032687230923192
Pubmed

Site-specific N-glycosylation and oligosaccharide structures of recombinant HIV-1 gp120 derived from a baculovirus expression system.

GLT8D1 MAN2A1

1.93e-03268728218172
Pubmed

Proximity interactions among centrosome components identify regulators of centriole duplication.

SIPA1L1 TRIM37 PCNT

2.11e-0310187324613305
Pubmed

N-Terminomics for the Identification of In Vitro Substrates and Cleavage Site Specificity of the SARS-CoV-2 Main Protease.

RABEP2 PTPRB APC ZNF579 PCNT

2.13e-0336087533111431
Pubmed

Ubiquitin-Independent Disassembly by a p97 AAA-ATPase Complex Drives PP1 Holoenzyme Formation.

STARD9 APC LMTK2 TTC13 KNL1

2.16e-0336187530344098
Pubmed

Targeted proteomic analysis of 14-3-3 sigma, a p53 effector commonly silenced in cancer.

SIPA1L1 APC ARHGAP11A

2.17e-0310287315778465
Pubmed

Prediction of the coding sequences of unidentified human genes. VII. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro.

AKAP6 ZFYVE16 CABIN1

2.29e-031048739205841
Pubmed

JMJD1C Exhibits Multiple Functions in Epigenetic Regulation during Spermatogenesis.

CHD5 ETV5

2.40e-032987227649575
Pubmed

Oncogenic RAS directs silencing of tumor suppressor genes through ordered recruitment of transcriptional repressors.

SIPA1L2 TRIM37

2.40e-032987224105743
Pubmed

Tbx18 Regulates the Differentiation of Periductal Smooth Muscle Stroma and the Maintenance of Epithelial Integrity in the Prostate.

TBX15 IRX2

2.40e-032987227120339
Cytoband5q21-q22

MAN2A1 APC

2.12e-0548725q21-q22
GeneFamilyPDZ domain containing

SIPA1L1 FRMPD1 SIPA1L2 SHROOM2 TIAM2

2.01e-041526451220
GeneFamilyFibronectin type III domain containing

CHL1 NPHS1 ROBO4 PTPRB USH2A

2.55e-04160645555
GeneFamilyWD repeat domain containing

PIK3R4 AAMP WDR88 PAFAH1B1 APAF1

2.34e-03262645362
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Cycling_Endothelial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

NCAPD3 PTPRB STARD9 FBXO43 ARHGAP11A KNL1

1.99e-0619087631de1727822e9818652946dfb962daee77ffad68
ToppCell367C-Myeloid-Dendritic-cDC_proliferating_2|367C / Donor, Lineage, Cell class and subclass (all cells)

FBXO43 ETV5 ARHGAP11A KNL1 ZNF2

1.76e-051648750662cd9d21608efacc336e0a582859f3b9a4951d
ToppCellsevere_influenza-Plasmablast|World / disease group, cell group and cell class (v2)

TBX15 CBY3 SLC17A9 MNX1 CCDC168

2.40e-05175875e6d6c44510d5dc4eb0bae820125e42366f7a4e74
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell_cycling|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

NCAPD3 MED12L FBXO43 ARHGAP11A KNL1

2.75e-05180875401df9cddcbca1eb8f0d2687bcacd98e95dc1493
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d02_child-Lymphocytic-Lymphocytic_B-Plasma_cell-B_c06-MKI67|Mild-Moderate_progression_d02_child / Compartment, severity and other cell annotations on 10x 3' data (130k)

ESYT3 NCAPD3 SLC17A9 ARHGAP11A PLA2G4D

2.82e-05181875c18e5a3f5d99043fa3cb33e2ac33fa98cd15d3db
ToppCellAdult-Endothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)-D175|Adult / Lineage, Cell type, age group and donor

CHL1 ROBO4 STARD9 SIPA1L2 DISP1

2.90e-051828758b4a07ebd7a133a33ef333cfa29d12c4f3d4d9ac
ToppCell367C-Epithelial_cells-Epithelial-A_(AT2)|367C / Donor, Lineage, Cell class and subclass (all cells)

ESYT3 ETV5 IRX2 LRRC36 TMEM213

3.05e-051848750ba243cbf69b4fe6ae100a7f0314317bec38026c
ToppCellControl-Epithelial_alveolar-AT_2|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

FREM2 IMPA2 ETV5 IRX2 TMEM213

3.05e-0518487551e129b3fcc2df083eda05a3afe3717218b1e52b
ToppCell367C-Epithelial_cells-Epithelial-A_(AT2)-|367C / Donor, Lineage, Cell class and subclass (all cells)

ESYT3 ETV5 IRX2 LRRC36 TMEM213

3.05e-051848752a8338e94937686a148b5433515700ca0f674058
ToppCellCOVID-19-lung-Plasma_cells_PRDM1/BLIMP_hi|lung / Disease (COVID-19 only), tissue and cell type

SLC17A9 NUP210 ARHGAP11A TXNDC11 KNL1

3.21e-0518687566676d9395172de5707e204826a1c9f73b448cca
ToppCellDividing_Macrophages-Myositis-ILD_01|World / lung cells shred on cell class, cell subclass, sample id

NCAPD3 FBXO43 CD180 ARHGAP11A KNL1

3.21e-051868750067eb78d4c7e32b9563550d9fcaf13445ee6a48
ToppCellPCW_13-14-Epithelial-Epithelial_alveolar-distal-epi_SOX9^high_Etv5^high_distal_(10)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

ESYT3 FREM2 NUP210 IRX2 LRRC36

3.21e-05186875bb0bfe9a015151be08a6ffc5d82896d0556d76de
ToppCellCOVID-19-lung-Plasma_cells_PRDM1/BLIMP_hi|COVID-19 / Disease (COVID-19 only), tissue and cell type

SLC17A9 NUP210 ARHGAP11A TXNDC11 KNL1

3.38e-05188875567b08514d9d84cbb40f9b7a679eec304f023428
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_2-D231|Adult / Lineage, Cell type, age group and donor

ESYT3 FREM2 ETV5 LRRC36 TMEM213

3.47e-05189875dab54a52358f66a8a9460cd6089a06c5fa7e7a5d
ToppCellPCW_07-8.5-Epithelial-Epithelial_alveolar-distal-epi_SOX9^high_Etv5^high_distal_(10)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

FREM2 NUP210 ETV5 IRX2 LRRC36

3.56e-05190875625c08a0e5227efc46daa512fd579c3938ff76c7
ToppCellwk_20-22-Epithelial-Distal_epithelial_progenitor|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

ESYT3 FREM2 ETV5 IRX2 LRRC36

3.74e-05192875fa2420d6117d4800f60ef6a24bcf8bf54593cd1f
ToppCellwk_20-22-Epithelial-Distal_epithelial_progenitor-epi-tip_late|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

ESYT3 FREM2 ETV5 IRX2 LRRC36

3.74e-0519287587b60014202633a4f6d19b09a5dd9276c2edecfb
ToppCellPCW_07-8.5-Epithelial-Epithelial_alveolar-distal|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

FREM2 NUP210 ETV5 IRX2 LRRC36

3.74e-05192875b7c01e12b3e9be960a741b08835f1dfff65d0d47
ToppCellTCGA-Prostate-Primary_Tumor-Prostate_Adenocarcinoma-Acinar_Adenocarcinoma-6|TCGA-Prostate / Sample_Type by Project: Shred V9

DIP2B MAN2A1 ATR ZFYVE16 BIRC6

3.83e-05193875abd71b2cf667ef2b1c4d88acd0c1dd19a12ff659
ToppCellPCW_13-14-Epithelial-Epithelial_proliferating-epi_proliferating2_(13)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

FREM2 FBXO43 ARHGAP11A IRX2 KNL1

3.93e-05194875c197e4acbff42a9f0410b6801c2bfcf6160aefc1
ToppCellPCW_05-06-Epithelial-Epithelial_alveolar-distal-epi_SOX9^high_Etv5^medium_distal_(2)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

FREM2 NUP210 ETV5 IRX2 LRRC36

3.93e-05194875413112ee8df7407fd418d57c2ff11aad3a6ec259
ToppCellPCW_13-14-Epithelial-Epithelial_proliferating-epi_proliferating3_(5)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

ESYT3 FREM2 NUP210 IRX2 LRRC36

3.93e-05194875c011cd59bb4ca4134331cba0f5d73bdbd7011d64
ToppCellPCW_05-06-Epithelial-Epithelial_alveolar-distal|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

FREM2 NUP210 ETV5 IRX2 LRRC36

3.93e-05194875acd5ba9a097595d4caab4f05440531c65a4aa7bc
ToppCellPCW_10-12-Epithelial-Epithelial_proliferating-epi_proliferating3_(5)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

ESYT3 FREM2 NUP210 IRX2 LRRC36

4.02e-0519587598dd3b7d5ef587825dac052dea4d4ff883f6d4d6
ToppCellPCW_10-12-Epithelial-Epithelial_proliferating|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

ESYT3 FREM2 NUP210 IRX2 LRRC36

4.02e-05195875ce1ba5911e8a6ddb07434acc37147c38e94245ff
ToppCellCOVID-19-T_cells-Cycling_NK/T_cells|COVID-19 / group, cell type (main and fine annotations)

NCAPD3 NUP210 ARHGAP11A KNL1 PCNT

4.02e-05195875764ed100c28d9bc93ee5ecabc5291c8f184d78da
ToppCellPCW_13-14-Epithelial-Epithelial_proliferating|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

ESYT3 FREM2 NUP210 IRX2 LRRC36

4.12e-051968757b17d47b7758d8ccf9dbefd097aeb553791a1eed
ToppCellCOVID-19-lung-Capillary_Aerocytes|lung / Disease (COVID-19 only), tissue and cell type

CHL1 ROBO4 STARD9 SIPA1L2 SHROOM2

4.12e-051968754ac4073380d939a73cec7413e9f3f5ef616d2924
ToppCellwk_08-11-Epithelial-Distal_epithelial_progenitor-epi-tip_intermediate|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

ESYT3 FREM2 ETV5 IRX2 LRRC36

4.33e-0519887584697f316d9195ebe838cf57f4dbdd9feea43bec
ToppCellwk_08-11-Epithelial-Distal_epithelial_progenitor|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

ESYT3 FREM2 ETV5 IRX2 LRRC36

4.33e-05198875eda85a592527992b51a00f288cff0c3239c47e6f
ToppCellNeuron-Postmitotic-Excitatory_Neuron_-Parietal_and_Temporal-6|World / Primary Cells by Cluster

CHL1 ZBTB38 CHD5 PCDH11Y APC

4.43e-051998751b1bccf4293f11048709d15a3c892c0edf3da3d2
ToppCellNeuron-Postmitotic-Excitatory_Neuron_-Parietal_and_Temporal|World / Primary Cells by Cluster

CHL1 ZBTB38 CHD5 PCDH11Y APC

4.43e-051998754bee94c116c0da5eba951cb4cea7cc9dcdd6e30f
ToppCellLung_Parenchyma-Control-Epithelial-Epithelial-AT2-2-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

ESYT3 FREM2 ETV5 IRX2 LRRC36

4.54e-052008753c251ad03fbbdae91dfd9037880ba43adbb03807
ToppCellLung_Parenchyma-Control-Epithelial-Epithelial-AT2-2|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

ESYT3 FREM2 ETV5 IRX2 LRRC36

4.54e-05200875c905451425d1c24773bb0ca69bcf0309b277d2f1
ToppCellParenchyma_Control_(B.)-Epithelial-TX-AT2-2|Parenchyma_Control_(B.) / Sample group, Lineage and Cell type

ESYT3 FREM2 ETV5 IRX2 LRRC36

4.54e-0520087535c05cae30cd6b323d2662f1396ddeab08bc75fc
ToppCellfacs-Brain_Non-Myeloid-Striatum-24m-Macroglial-astrocyte|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MICAL1 DRP2 IMPA2 RUBCN

9.93e-05123874a45d6907c041ad3f3218cd46dccfc25d4bd961cb
ToppCellLPS-IL1RA+antiTNF-Epithelial_alveolar-AT_2-AT1-AT2|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ESYT3 IMPA2 IRX2 TMEM213

1.30e-04132874c6bf0b4b9e33b517629faf4559a21d7ba720ee6a
ToppCellLPS_only-Endothelial-Endothelial-FOXM1|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PASK ARHGAP11A TIAM2 KNL1

1.38e-041348744d8f7ddad02fe76a614771e115ebb8e04623ba85
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22-Lymphocytic-Lymphocytic_T-CD8-positive,_mature_gamma-delta_T_cell-T_gdT_c14-TRDV2|Severe-critical_progression_d12-22 / Compartment, severity and other cell annotations on 10x 3' data (130k)

SERGEF TENM1 ETV5 DISP1

2.19e-0415187429d91a7d1470121af45fb8bb35175f2acced4551
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22-Lymphocytic-Lymphocytic_T-CD8-positive,_mature_gamma-delta_T_cell|Severe-critical_progression_d12-22 / Compartment, severity and other cell annotations on 10x 3' data (130k)

SERGEF TENM1 ETV5 DISP1

2.19e-041518749ebfbdccc9656fce8990d06622f225009633f07c
ToppCellPND14-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_T-CD8_T-CD8_T_prolif|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PASK SLC17A9 BAIAP3 TRIM37

2.66e-04159874e9c51e611ebd427bbe51e3e036c14122c36ea372
ToppCell18-Airway-Epithelial-Bud_tip_progenitor|Airway / Age, Tissue, Lineage and Cell class

ESYT3 ETV5 ZNF579 IRX2

2.66e-04159874e715cadff8e7d5ebe4c2198dbdfd3ca41ecb8a6a
ToppCell390C-Myeloid-Macrophage-SPP1+_Macrophage_2|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

ESYT3 SH3D19 MCF2L2 PIGG

2.79e-041618742fe77af3b41e6eacb707a64feea18f9991618173
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c10-MKI67-GZMK|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

NUP210 ARHGAP11A KNL1 PCNT

2.86e-04162874af9999e5fcd28ff1f401d52fd220315752c40027
ToppCellPND10-Endothelial-Endothelial_blood-vessel-Microvascular_EC-EPC-EPC_mature|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ROBO4 NCAPD3 PTPRB KNL1

2.92e-041638743efbbdc9cb2613bb76d8c2f07cd4ec1a2c51a622
ToppCellLPS-antiTNF-Endothelial-Endothelial-FOXM1|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

NCAPD3 PTPRB ARHGAP11A KNL1

2.92e-041638745285318c52aa31c9b22dc2ffff078e32e408604d
ToppCellE18.5-samps-Endothelial-Mature_fetal_endothelial-endothelial_cells_B|E18.5-samps / Age Group, Lineage, Cell class and subclass

ROBO4 PTPRB SLC17A9 USH2A

2.92e-04163874d6f9b7280c44d120df5a72dfc2ebb26ffbb5752b
ToppCellNS-control-d_0-4-Myeloid-pDC|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

MED12L CCDC168 CD180 RUBCN

3.06e-041658748b2d43d7c4ee07bd999bd51bc15117ce1fbb2d86
ToppCellcontrol-Myeloid-pDC|control / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

MED12L CCDC168 CD180 RUBCN

3.06e-04165874243c74adf8d993ff92acbff2768bdc5a1693eca3
ToppCell368C-Endothelial_cells-Endothelial-C_(Capillary_Aerocyte_)|368C / Donor, Lineage, Cell class and subclass (all cells)

PASK ROBO4 PCDH11Y DISP1

3.13e-0416687430a991fc3275b571d53bd0976df4789e5d40b01d
ToppCell368C-Endothelial_cells-Endothelial-C_(Capillary_Aerocyte_)-|368C / Donor, Lineage, Cell class and subclass (all cells)

PASK ROBO4 PCDH11Y DISP1

3.13e-0416687476b4cd32698900797ec009f17e50ea7ae36b85f4
ToppCellAdult-Endothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)-D231|Adult / Lineage, Cell type, age group and donor

CHL1 ROBO4 STARD9 DISP1

3.21e-041678745af9127bae05768a5164d5708a4ad37edca99324
ToppCell367C-Epithelial_cells-Epithelial-B_(AT2)|367C / Donor, Lineage, Cell class and subclass (all cells)

ESYT3 IRX2 LRRC36 TMEM213

3.28e-04168874e20e1936573fdde78426d7a4eb45c458d5c4dbb4
ToppCell367C-Epithelial_cells-Epithelial-B_(AT2)-|367C / Donor, Lineage, Cell class and subclass (all cells)

ESYT3 IRX2 LRRC36 TMEM213

3.28e-0416887416b517e3159ad6e6d25fd48f7d5f46e77b2b318d
ToppCellE18.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF1-AF1_prolif|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ESYT3 STARD9 ANKS3 ZNF697

3.35e-0416987416c52a0f6d96ecc1832922fce9b39691849f0d73
ToppCell5'-GW_trimst-1.5-LargeIntestine-Mesenchymal-fibroblastic-Stromal_1_(ADAMDEC1+)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ARHGAP11A TUBD1 IRX2 KNL1

3.43e-04170874a7184dc41f90caa753860ed0f65a18133f84bc5f
ToppCellhealthy_donor-Myeloid-Monocytic-Developing_Neutrophil|healthy_donor / Disease condition, Lineage, Cell class and subclass

ZNF670 ARHGAP11A DISP1 KNL1

3.43e-04170874cfd7f29805b7c51666b0eaf269c36c96b8765a1a
ToppCellP15-Mesenchymal-developing_mesenchymal_cell-mesenchymal_proliferating_cell|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

PASK IMPA2 SHROOM2 KNL1

3.59e-041728747c238a7375341d4647ba7274d93fddfb6fae7ce4
ToppCell(01)_Cycling_Basal_(homeostasis)-(1)_24hpi|(01)_Cycling_Basal_(homeostasis) / shred by cell type and Timepoint

NUDT6 USH2A TIAM2

3.63e-04718736aa56b0daaeb5e0ae30619f9c6945c8e42899b27
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

NCAPD3 FBXO43 ARHGAP11A KNL1

3.75e-0417487484da9faff088d05233183b425385beb054c92d1b
ToppCellsevere_influenza-Plasmablast|severe_influenza / disease group, cell group and cell class (v2)

TBX15 SLC17A9 MNX1 CCDC168

3.75e-041748748c6c4d794373e774ecb3382cb7163b4246b98780
ToppCellPND03-Immune-Immune_Myeloid-Monocytic-Macrophage-AM-AM_G2M|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CHD5 ARHGAP11A ABHD12 KNL1

3.75e-0417487465147b0f8c2ccadd5685430d31081520c157536a
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_G2M|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

NCAPD3 FBXO43 ARHGAP11A KNL1

3.75e-04174874dbb4e1a6c3319ce40f81bfd2d1745a88a2cc412e
ToppCellE18.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-VSMC-VSMC_G2M|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

AKAP6 NCAPD3 ARHGAP11A KNL1

3.75e-0417487441eb0a214a8b4015a26311f77061c8147144f0e7
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Immune-Myeloid-Macrophage_Dendritic-Cycling_Mononuclear_Phagocyte|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

SLC17A9 NUP210 ARHGAP11A KNL1

3.83e-04175874f7d191cde68de8f3457fa62b1df53b6d0dbe5001
ToppCellPND03-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-VEC-VEC_G2M|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PTPRB DRP2 CCDC168 KNL1

3.83e-04175874d43ae33a6256606ce848247cad32d74f21b38988
ToppCellInfluenza_Severe-Plasmablast|Influenza_Severe / Disease group and Cell class

TBX15 SLC17A9 MNX1 FRMPD1

3.83e-041758743f9b9793d3d1b7a9b97899272b6a0d37b05c11d1
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell_cycling-Cycling_Distal_Convoluted_Tubule_Cell_G2M|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

NCAPD3 FBXO43 ARHGAP11A KNL1

3.83e-04175874876cea684faf42ff3eb4623ad6d7a1fb1276ee02
ToppCellfacs-SCAT-Fat-3m-Lymphocytic-CD8-positive,_alpha-beta_T_cell|SCAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NUP210 TENM1 FBXO43 BAIAP3

4.00e-04177874ffc4c675b25ffe8bd3441ce26dd0984fef4b3b88
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Cycling_Endothelial_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ROBO4 FBXO43 ARHGAP11A KNL1

4.00e-0417787473ba0f0b4b33f10e9f036d6d9befa48a1258e682
ToppCellC_00|World / shred on cell type and cluster

ZBTB38 NUP210 MLXIP ANKS3

4.17e-04179874da2dadc3266ffebd4a34ac61bfa05fddcadcde4c
ToppCellControl-Endothelial_cells-Capillary_endothelial_cells|Control / group, cell type (main and fine annotations)

CHL1 ROBO4 SIPA1L2 SHROOM2

4.26e-04180874b043f9ffb9a4cd427a15bebb86a711c7b08866e8
ToppCellSevere-B_memory-3|World / disease group and sub_cluster of B and Plasma cells(res = 0.5)

ZBTB38 OR52N2 BAIAP3 TIAM2

4.26e-0418087490b812c5450359b1745b413421b71e291c97086a
ToppCellfacs-Limb_Muscle-ForelimbandHindlimb-24m-Endothelial-nan|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CHL1 ROBO4 FREM2 PTPRB

4.35e-041818740756d7d315b8cdd07a3cf6cdfc8a0679786b8e6a
ToppCellfacs-Limb_Muscle-ForelimbandHindlimb-24m-Endothelial-endothelial_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CHL1 ROBO4 FREM2 PTPRB

4.35e-04181874b09947d2d7b21f96d98b87ceb6f467ea329c4092
ToppCell5'-Parenchyma_lung-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophage_proliferating-Alveolar_macrophage_proliferating_L.1.0.7.2|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

NCAPD3 FBXO43 ARHGAP11A KNL1

4.35e-0418187473b1b59810f60e3e39ca1d5073a5a0d4f5377e6e
ToppCellfacs-Limb_Muscle-ForelimbandHindlimb-24m-Endothelial|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CHL1 ROBO4 FREM2 PTPRB

4.35e-041818743f0d88e9506d66d4e71b88c50d5187302065930f
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell_cycling-Cycling_Connecting_Tubule_Cell_G2M|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

NCAPD3 FBXO43 ARHGAP11A KNL1

4.44e-04182874336cd05e46a741185ce3c59ee67a4b07fa6a5101
ToppCell5'-Adult-SmallIntestine-Hematopoietic-Plasma_cells-IgA_plasma_cell|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ZBTB38 SLC17A9 RUBCN TXNDC11

4.44e-04182874626aabfd9ac662c1d189f7c4b660482914d9e669
ToppCellLPS-antiTNF-Epithelial_alveolar-AT_2-AT2|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

IMPA2 ETV5 IRX2 TMEM213

4.44e-041828741e2149b222a3e9f64841aed45288a6f29394e7b0
ToppCell3'-GW_trimst-1.5-SmallIntestine-Neuronal-neurons_A-Branch_A4_(IN)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

AKAP6 CHD5 MCF2L2 MED12L

4.44e-04182874be32b5b8153c1053cbb55f1fccfa27c3ee97c1e1
ToppCellControl-Epithelial_alveolar-AT_2-AT2|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

IMPA2 ETV5 IRX2 TMEM213

4.44e-04182874e97681a4102f3095d5d9e90ad70f1dc46e90983a
ToppCell343B-Lymphocytic-NK_cells-Proliferating_NK_cell|NK_cells / Donor, Lineage, Cell class and subclass (all cells)

PASK NCAPD3 IMPA2 KNL1

4.44e-04182874b1e66ccd5f33b4801f1cafddf97f5fc0c6dba8d1
ToppCell5'-Adult-SmallIntestine-Hematopoietic-Plasma_cells|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ZBTB38 SLC17A9 RUBCN TXNDC11

4.44e-04182874a00abff41c12b71d5860c494b8c722d649fd5f36
ToppCellPCW_07-8.5-Neuronal-Neuronal_postreplicative-neuro_neuronal_(6)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

AKAP6 CHL1 CHD5 APC2

4.62e-04184874571136c832cb8c08457744152231537aa8e8abd7
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FREM2 DRP2 TENM1 USH2A

4.62e-041848742cbed6462fea2622871bb7e49b0df3d984239281
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell__prolif|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ROBO4 PTPRB STARD9 SIPA1L2

4.62e-04184874688428103e8b19f45f2f65d70a0f30c904c8411c
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FREM2 DRP2 TENM1 USH2A

4.62e-04184874ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FREM2 DRP2 TENM1 USH2A

4.62e-041848742b19a8c5f823e00812908b23e66bb4e563278aff
ToppCellPCW_05-06-Epithelial-Epithelial_alveolar-distal-epi_SOX9^high_Etv5^high_distal_(10)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

FREM2 ETV5 IRX2 LRRC36

4.62e-04184874fa4915b0498f3069fd5ef497286445528f75187e
ToppCellwk_20-22-Epithelial-PNS-intermediate_Schwann|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

CHL1 ZNF670 SIPA1L2 ABHD12

4.62e-041848744e3ba64692868563a579902aa9c6f88cab5bce26
ToppCellPBMC-Convalescent-Lymphocyte-B-B_cell-B_memory-B_memory-3|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

MED12L CD180 BAIAP3 TIAM2

4.72e-0418587405e6eb78ead81268c1656e7ffe34f9cb7329b908
ToppCell3'-GW_trimst-1.5-LargeIntestine-Endothelial-blood_vessel_EC-Fetal_arterial_EC|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ROBO4 PTPRB RNF19A LRRC36

4.72e-04185874602536a3308a848f106adcb0a83530997440c8f4
ToppCell343B-Endothelial_cells-Endothelial-E-|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)

ROBO4 PTPRB LMTK2 DISP1

4.82e-04186874dae6a98963c78bf7518ebab8dc02f173c3b0f7f7
ToppCell343B-Endothelial_cells-Endothelial-E|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)

ROBO4 PTPRB LMTK2 DISP1

4.82e-04186874080e56113b89138277a2bd2eabddfa6cd1a18b61
ToppCellControl-Epithelial-ATII|World / Disease state, Lineage and Cell class

ESYT3 FREM2 IRX2 LRRC36

4.82e-04186874f4b6e401e19a71beddc73d8a1e08359f7c4025cf
ToppCellPCW_10-12-Epithelial-Epithelial_alveolar-distal-epi_SOX9^high_Etv5^high_distal_(10)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

ESYT3 FREM2 IRX2 LRRC36

4.91e-04187874db2974e2e87ac9f1c2407a371d5ed89af09fc9b7
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell_cycling|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

NCAPD3 FBXO43 ARHGAP11A KNL1

4.91e-04187874057569c9437219ecc396aa6e673b1178a2273837
ToppCellLAM-Endothelial-VasEndo-1|Endothelial / Condition, Lineage and Cell class

CHL1 PASK ROBO4 DISP1

5.01e-04188874f24c33d960ca93459584a79ff8f0ec20db6a34d5
ToppCell3'-GW_trimst-1-LargeIntestine-Neuronal-neurons_A-Branch_A3_(IPAN/IN)|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

AKAP6 CHL1 CHD5 APC2

5.01e-04188874bd091503f580dedab40e0996273101285d24b586
Diseasefamilial adenomatous polyposis 1 (implicated_via_orthology)

APC2 APC

8.59e-062872DOID:0080409 (implicated_via_orthology)
DiseaseMalignant neoplasm of breast

AKAP6 PIK3R4 MICAL1 WDR88 NOA1 SIPA1L1 CHD5 APC2 FRMPD1 MCF2L2 TENM1 ARHGAP11A SHROOM2

1.54e-0510748713C0006142
DiseaseSeckel syndrome 1

ATR PCNT

2.57e-053872C4551474
Diseaseprostate carcinoma, type 2 diabetes mellitus

AKAP6 ZBTB38 LMTK2 KNL1

2.83e-0559874EFO_0001663, MONDO_0005148
DiseaseUsher syndrome (is_implicated_in)

USH2A ARSG

5.14e-054872DOID:0050439 (is_implicated_in)
Diseasesarcoma (is_implicated_in)

PTPRB KNL1

2.38e-048872DOID:1115 (is_implicated_in)
Diseasecolon cancer (implicated_via_orthology)

ATR APC

4.65e-0411872DOID:219 (implicated_via_orthology)
Diseasethyroid gland carcinoma (is_marker_for)

ROBO4 PTPRB

5.56e-0412872DOID:3963 (is_marker_for)
Diseaseprimary autosomal recessive microcephaly (is_implicated_in)

NCAPD3 KNL1

1.00e-0316872DOID:0070296 (is_implicated_in)
DiseaseColorectal Carcinoma

AKAP6 CHL1 GHRHR CHD5 APC2 MCF2L2 TENM1 APC

1.11e-03702878C0009402
DiseaseBenign neoplasm of stomach

ATR APC

1.14e-0317872C0153943
DiseaseEye Abnormalities

APAF1 APC

1.14e-0317872C0015393
DiseaseNeoplasm of uncertain or unknown behavior of stomach

ATR APC

1.14e-0317872C0496905
DiseaseCarcinoma in situ of stomach

ATR APC

1.14e-0317872C0154060
DiseaseChronic myeloproliferative disorder

ATR PCNT

1.42e-0319872C1292778
DiseaseStomach Carcinoma

ATR APC

1.74e-0321872C0699791
DiseaseSeckel syndrome

ATR PCNT

1.91e-0322872C0265202
Diseasenucleus accumbens volume

USH2A BIRC6

1.91e-0322872EFO_0006931
DiseaseAutosomal Recessive Primary Microcephaly

NCAPD3 KNL1

1.91e-0322872C3711387
DiseaseS-6-hydroxywarfarin to S-warfarin ratio measurement

MAN2A1 SERGEF BIRC6

2.27e-0388873EFO_0803332
Diseasepallidum volume

BIRC6 ARSG

2.47e-0325872EFO_0006933
Diseasebreast cancer (implicated_via_orthology)

ATR APC

2.47e-0325872DOID:1612 (implicated_via_orthology)

Protein segments in the cluster

PeptideGeneStartEntry
CDISHDATKFSSTSA

APAF1

1091

O14727
SSLNSLASSCFDLAD

ESYT3

726

A0FGR9
SFCFSHISSSESIAQ

BIRC6

3641

Q9NR09
FDSASIHSASVRSEC

CHD5

301

Q8TDI0
TFALHSASVFCVSLD

AAMP

86

Q13685
SVTCAGFSHDSTLVA

AAMP

136

Q13685
SRHSSSAATAGLCLS

BAIAP3

731

O94812
DFHAAASTCSPSRAS

ARSG

76

Q96EG1
DLSHNSLTCDSIDSL

CD180

526

Q99467
HALATFECSATSHAS

CBY3

56

A6NI87
CSAFSHALSTSPSDK

DISP1

1151

Q96F81
AEAFAHNCDDSASIS

RABEP2

221

Q9H5N1
HNCDDSASISSFSLG

RABEP2

226

Q9H5N1
ISFDHSGKLLASCSA

PAFAH1B1

156

P43034
SSSGSAAAALDADCR

ABHD12

21

Q8N2K0
GASEVVTLSDCSHFD

NUP210

566

Q8TEM1
AAGDSTSSATLHCRA

NPHS1

851

O60500
RCNFTLAESKASSHS

PTPRB

26

P23467
SDGTVTSCDSLFAHL

PASK

246

Q96RG2
CTVDVSDLSFHDSLA

MED12L

1071

Q86YW9
VDTADCLFASQSGSH

MAN2A1

111

Q16706
CSAHTALDSAADITQ

CHL1

591

O00533
SNGASVHAASSDCSS

MNX1

371

P50219
SYAHNGDKSLTDSCS

FREM2

901

Q5SZK8
QDLSFCQDLSSSLHS

FAM89B

126

Q8N5H3
LAGLFQSDDSHETCS

MCF2L2

1036

Q86YR7
QSDDSHETCSSKSAF

MCF2L2

1041

Q86YR7
TASHSCGDLLTSLSN

LRRC36

371

Q1X8D7
SLTHDTSISFFGCAL

OR14L1P

86

Q8NHC6
LGFCFHHAESDSSTL

NUDT6

111

P53370
SVSSCDAFLSLFQSH

DIP2B

646

Q9P265
VDFTSSHATAVCGSS

KNL1

1311

Q8NG31
DESCLSALHNSSDLE

LMTK2

1161

Q8IWU2
SCSALARHALESSFV

MICAL1

836

Q8TDZ2
GHAAAFSEDCDSAST

GLT8D1

191

Q68CQ7
SSELSSCSHEQALGA

ETV5

96

P41161
SSADARHKAFSTCTS

OR52N2

231

Q8NGI0
SSTLALCHLASGAAD

IMPA2

206

O14732
ASAHLLESSWSDDSC

PCNT

2101

O95613
SLHVDSLTDHSCSAE

IRX2

221

Q9BZI1
SITHDFSDSSLCIND

FBXO43

261

Q4G163
SFGKTSSCHLSIDAS

MLXIP

111

Q9HAP2
NFSCASSLSALALHE

APC2

1271

O95996
SHSDDGCLKLTTFAA

ATR

601

Q13535
ACLVDEDSHSSAGTL

CABIN1

1316

Q9Y6J0
DLDTCSSSRSTFFHF

FRMPD1

616

Q5SYB0
LFHSDDTDHCSFSTV

GHRHR

186

Q02643
HAASALTNSSASCES

FBXO40

226

Q9UH90
SSSSSREEHAFCANL

ANKS3

331

Q6ZW76
SVFSHILNTSDCGAS

CCDC168

3581

Q8NDH2
FSHCFLHSTSAEAVA

RUBCN

616

Q92622
CAAASSFQHSSSLGR

NOA1

36

Q8NC60
AADQFHHSSSLRSTC

DRP2

21

Q13474
SKAFSTCSSHLAAVG

OR8A1

251

Q8NGG7
LDHSSSSQAQASALC

PCDH11Y

1151

Q9BZA8
ACASRQLHSLASFST

INCA1

201

Q0VD86
LSCLDVHLDSTGSTA

PLA2G4D

161

Q86XP0
PDRSTFCHSSAAAES

USH2A

61

O75445
CAAHSKDEARSSFSQ

ARHGAP11A

751

Q6P4F7
CVLAGSDHSASLTDA

SERGEF

216

Q9UGK8
THLCSAATSSLLDID

TRIM37

601

O94972
CEALHSFTAETSDDL

SH3D19

666

Q5HYK7
SCSFSTHTDLASGAA

TBX15

86

Q96SF7
SFESTLSSHCTNAGV

SIPA1L1

446

O43166
SFESSLSSHCTNAGV

SIPA1L2

441

Q9P2F8
SSGRCHSADDILDVS

SHROOM2

891

Q13796
HTSSFCESVVFASAS

SLC17A9

331

Q9BYT1
EHSSCLSSRANSALS

TENM1

131

Q9UKZ4
QSEASFCSSLHSAHR

SPSB3

76

Q6PJ21
LCSARDEHTASAADT

STARD9

1406

Q9P2P6
SSAFSHGASTVACDD

REELD1

21

A0A1B0GV85
SLVSSSDGSFLADAH

ROBO4

891

Q8WZ75
NEDLFSCHSSGDISV

AKAP6

1606

Q13023
VCFSHNSSLSSLSDI

APC

1961

P25054
SSFAHCLELTVTSAS

NCAPD3

466

P42695
VSDEHSLFATCSNDG

PIK3R4

1001

Q99570
DALLSDSHSSQGLCS

TUBD1

21

Q9UJT1
SAECGESSFLNFHDS

TTC13

86

Q8NBP0
SDCGKTFFDHSSLTR

ZNF2

176

Q9BSG1
EGSVSSCHFARDSSF

WDR88

321

Q6ZMY6
SVSSFHALVCSRDDS

TIAM2

731

Q8IVF5
ADSHSSHFSEFSCSD

RNF19A

721

Q9NV58
ILSSSHSSDTLCNAD

USP47

961

Q96K76
HVASDSIECSNFLTS

TXNDC11

511

Q6PKC3
ECGEAFSLSSHLLSH

ZNF697

321

Q5TEC3
CCSKAFDSSTLLSAH

ZBTB38

346

Q8NAP3
SFSHFTDQELRDCSS

nan

156

Q8N1Y9
LSSETRSGSALSHAC

PIGG

906

Q5H8A4
LAFASLHSACSAEAS

TMEM213

16

A2RRL7
VFLSASCFDSQDHSA

ZNF579

526

Q8NAF0
GASFSTEADSHLVCI

ZFYVE16

1281

Q7Z3T8
ECGKSFTSSSALRSH

ZNF670

341

Q9BS34