Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctiontransporter activity

SLC30A7 SLC43A2 VMP1 SCN11A SIDT2 KCNH8 PLSCR5 SLC25A4 SLC17A9 SCN7A SLC9B1P1 AQP7P3 SEC63 NDUFB3 AQP5 SVOP MFSD1

4.38e-0612897517GO:0005215
GeneOntologyMolecularFunctiontransmembrane transporter activity

SLC30A7 SLC43A2 SCN11A SIDT2 KCNH8 SLC25A4 SLC17A9 SCN7A SLC9B1P1 AQP7P3 SEC63 NDUFB3 AQP5 SVOP MFSD1

2.74e-0511807515GO:0022857
GeneOntologyMolecularFunctionribonucleoside-diphosphate reductase activity

RRM2B RRM2

4.17e-053752GO:0061731
GeneOntologyMolecularFunctionribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor

RRM2B RRM2

4.17e-053752GO:0004748
GeneOntologyMolecularFunctionoxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor

RRM2B RRM2

1.38e-045752GO:0016728
GeneOntologyMolecularFunctionuniporter activity

SLC17A9 MFSD1

6.14e-0410752GO:0015292
GeneOntologyMolecularFunctionADP transmembrane transporter activity

SLC25A4 SLC17A9

7.49e-0411752GO:0015217
GeneOntologyMolecularFunctionAP-2 adaptor complex binding

SIDT2 OTOF

1.23e-0314752GO:0035612
GeneOntologyMolecularFunctionATP transmembrane transporter activity

SLC25A4 SLC17A9

1.23e-0314752GO:0005347
GeneOntologyMolecularFunctionoxidoreductase activity, acting on CH or CH2 groups

RRM2B RRM2

1.42e-0315752GO:0016725
GeneOntologyMolecularFunctionnucleobase-containing compound transmembrane transporter activity

SIDT2 SLC25A4 SLC17A9

1.42e-0359753GO:0015932
GeneOntologyCellularComponentribonucleoside-diphosphate reductase complex

RRM2B RRM2

3.90e-053762GO:0005971
GeneOntologyCellularComponentendoplasmic reticulum-Golgi intermediate compartment

VMP1 MGAT4D PROM1 NAT8B FTCD

1.64e-04141765GO:0005793
GeneOntologyCellularComponentnuclear outer membrane-endoplasmic reticulum membrane network

SLC30A7 VMP1 MGAT4D TMEM67 NAT8B PIGT OTOF GUCY2F AGMO NUP210 NCEH1 FTCD SEC63 PIGO

2.71e-0413277614GO:0042175
GeneOntologyCellularComponentendoplasmic reticulum membrane

SLC30A7 VMP1 MGAT4D TMEM67 NAT8B PIGT OTOF AGMO NUP210 NCEH1 FTCD SEC63 PIGO

7.25e-0412937613GO:0005789
GeneOntologyCellularComponentendoplasmic reticulum subcompartment

SLC30A7 VMP1 MGAT4D TMEM67 NAT8B PIGT OTOF AGMO NUP210 NCEH1 FTCD SEC63 PIGO

7.57e-0412997613GO:0098827
GeneOntologyCellularComponentsperm fibrous sheath

GSTM3 PGK2

9.91e-0413762GO:0035686
DomainRNR-rel

RRM2B RRM2

1.42e-052712IPR012348
DomainRNR_small_fam

RRM2B RRM2

1.42e-052712IPR000358
Domain-

RRM2B RRM2

1.42e-0527121.10.620.20
DomainRNR_small_AS

RRM2B RRM2

1.42e-052712IPR030475
DomainRNR_small

RRM2B RRM2

1.42e-052712IPR033909
DomainRibonuc_red_sm

RRM2B RRM2

1.42e-052712PF00268
DomainRIBORED_SMALL

RRM2B RRM2

1.42e-052712PS00368
DomainMFS_1

SLC43A2 SLC17A9 SVOP MFSD1

2.10e-0477714PF07690
DomainMFS

SLC43A2 SLC17A9 SVOP MFSD1

2.10e-0477714IPR011701
DomainNa_channel_asu

SCN11A SCN7A

6.29e-0410712IPR001696
DomainNa_trans_assoc

SCN11A SCN7A

6.29e-0410712IPR010526
DomainNa_trans_assoc

SCN11A SCN7A

6.29e-0410712PF06512
DomainMFS

SLC43A2 SLC17A9 SVOP MFSD1

7.63e-04108714PS50850
DomainFerritin-like_SF

RRM2B RRM2

1.26e-0314712IPR009078
DomainHEAT

NCAPD3 MRO EIF4G3

1.40e-0358713IPR000357
DomainMFS_dom

SLC43A2 SLC17A9 SVOP MFSD1

1.70e-03134714IPR020846
DomainHEAT_REPEAT

NCAPD3 MRO EIF4G3

2.40e-0370713PS50077
PathwayWP_BIOMARKERS_FOR_PYRIMIDINE_METABOLISM_DISORDERS

DPYD RRM2B RRM2

2.76e-0515573M39841
PathwayWP_PYRIMIDINE_METABOLISM_AND_RELATED_DISEASES

DPYD RRM2B RRM2

6.80e-0520573M39765
Pubmed

ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.

SLC30A7 GSTM3 VMP1 BMP1 COL5A1 TMEM67 NCAPD3 PIGT MGAT5 NUP210 NCEH1 SEC63 EIF4G3 NT5DC1 CSGALNACT1 PIGO

5.71e-091201761635696571
Pubmed

Systematically defining selective autophagy receptor-specific cargo using autophagosome content profiling.

SLC30A7 GSTM3 WDR3 COL5A1 PIGT PDCD6IP NUP210 NCEH1 SEC63 RRM2 FKBP4 PIGO AKAP12

4.37e-061297761333545068
Pubmed

Crystal structural studies of changes in the native dinuclear iron center of ribonucleotide reductase protein R2 from mouse.

RRM2B RRM2

4.71e-06276215322079
Pubmed

Expression status of ribonucleotide reductase small subunits hRRM2/p53R2 as prognostic biomarkers in stage I and II non-small cell lung cancer.

RRM2B RRM2

4.71e-06276221965764
Pubmed

Structural basis on the dityrosyl-diiron radical cluster and the functional differences of human ribonucleotide reductase small subunits hp53R2 and hRRM2.

RRM2B RRM2

4.71e-06276220484015
Pubmed

Caspase-dependent Proteolysis of Human Ribonucleotide Reductase Small Subunits R2 and p53R2 during Apoptosis.

RRM2B RRM2

4.71e-06276225878246
Pubmed

Nomenclature of voltage-gated sodium channels.

SCN11A SCN7A

4.71e-06276211144347
Pubmed

Ribonucleotide reductase subunit switching in hepatoblastoma drug response and relapse.

RRM2B RRM2

4.71e-06276236882565
Pubmed

Redox property of ribonucleotide reductase small subunit M2 and p53R2.

RRM2B RRM2

4.71e-06276219082948
Pubmed

Enzymatic cleavage specificity of the proalpha1(V) chain processing analysed by site-directed mutagenesis.

BMP1 COL5A1

4.71e-06276217407447
Pubmed

Posttranslational regulation of IRF-4 activity by the immunophilin FKBP52.

IRF4 FKBP4

4.71e-06276210714679
Pubmed

Palmitoylation of vacuole membrane protein 1 promotes small extracellular vesicle secretion via interaction with ALIX and influences intercellular communication.

VMP1 PDCD6IP

4.71e-06276238403678
Pubmed

Ribonucleotide reductase expression in cervical cancer: a radiation therapy oncology group translational science analysis.

RRM2B RRM2

1.41e-05376223552804
Pubmed

Ribonucleotide reduction is a cytosolic process in mammalian cells independently of DNA damage.

RRM2B RRM2

1.41e-05376218997010
Pubmed

Mutation of RRM2B, encoding p53-controlled ribonucleotide reductase (p53R2), causes severe mitochondrial DNA depletion.

RRM2B RRM2

1.41e-05376217486094
Pubmed

In vitro characterization of enzymatic properties and inhibition of the p53R2 subunit of human ribonucleotide reductase.

RRM2B RRM2

1.41e-05376214729598
Pubmed

Characterization of enzymatic properties of human ribonucleotide reductase holoenzyme reconstituted in vitro from hRRM1, hRRM2, and p53R2 subunits.

RRM2B RRM2

1.41e-05376216376858
Pubmed

Post-translational regulation of CD133 by ATase1/ATase2-mediated lysine acetylation.

PROM1 NAT8B

1.41e-05376224556617
Pubmed

Biosynthetic processing of the pro-alpha 1(V)2pro-alpha 2(V) collagen heterotrimer by bone morphogenetic protein-1 and furin-like proprotein convertases.

BMP1 COL5A1

1.41e-05376211741999
Pubmed

The human ribonucleotide reductase subunit hRRM2 complements p53R2 in response to UV-induced DNA repair in cells with mutant p53.

RRM2B RRM2

2.82e-05476214583450
Pubmed

Essential role of Tip60-dependent recruitment of ribonucleotide reductase at DNA damage sites in DNA repair during G1 phase.

RRM2B RRM2

2.82e-05476220159953
Pubmed

Analysis of exome data for 4293 trios suggests GPI-anchor biogenesis defects are a rare cause of developmental disorders.

PIGT PIGO

2.82e-05476228327575
Pubmed

Mammalian p53R2 protein forms an active ribonucleotide reductase in vitro with the R1 protein, which is expressed both in resting cells in response to DNA damage and in proliferating cells.

RRM2B RRM2

2.82e-05476211517226
Pubmed

Wild-type p53 regulates human ribonucleotide reductase by protein-protein interaction with p53R2 as well as hRRM2 subunits.

RRM2B RRM2

2.82e-05476212615712
Pubmed

WDR37 syndrome: identification of a distinct new cluster of disease-associated variants and functional analyses of mutant proteins.

PACS1 EIF4G3

7.03e-05676234642815
Pubmed

Yeast two-hybrid screening for proteins that interact with alpha1-adrenergic receptors.

BMP1 ADRA1A

7.03e-05676215525470
Pubmed

Role of aquaporin water channels in kidney and lung.

AQP7P3 AQP5

9.83e-0577629822113
Pubmed

Identification of binding partners interacting with the α1-N-propeptide of type V collagen.

BMP1 COL5A1

9.83e-05776220979576
Pubmed

Interpreting cancer genomes using systematic host network perturbations by tumour virus proteins.

SLC30A7 VMP1 PIGT SIDT2 NCEH1 SEC63 PIGO

1.12e-0449976722810586
Pubmed

Aquaporin molecular biology and clinical abnormalities of the water transport channels.

AQP7P3 AQP5

1.68e-0497629757370
Pubmed

Characterization of the CLEAR network reveals an integrated control of cellular clearance pathways.

SERINC2 MFSD1

1.68e-04976221752829
Pubmed

Expression of mRNAs of the aquaporin family in mouse oocytes and embryos.

AQP7P3 AQP5

2.10e-041076210788316
Pubmed

Expression patterns of aquaporins in the inner ear: evidence for concerted actions of multiple types of aquaporins to facilitate water transport in the cochlea.

AQP7P3 AQP5

2.10e-041076212031518
Pubmed

Intersubspecific subcongenic mouse strain analysis reveals closely linked QTLs with opposite effects on body weight.

SCN7A FIGN

2.10e-041076221451961
Pubmed

mRNAs encoding aquaporins are present during murine preimplantation development.

AQP7P3 AQP5

2.10e-041076211066060
Pubmed

Assessment of a polymorphism of SDK1 with hypertension in Japanese Individuals.

NUP210 NCEH1 ALDH1L1 AKAP12

2.72e-0414276419851296
Pubmed

Association of genetic variants with hemorrhagic stroke in Japanese individuals.

NUP210 NCEH1 ALDH1L1 AKAP12

2.79e-0414376420198315
Pubmed

Multiple glycolytic enzymes are tightly bound to the fibrous sheath of mouse spermatozoa.

GSTM3 PGK2

3.07e-041276216687649
Pubmed

Signal sequence and keyword trap in silico for selection of full-length human cDNAs encoding secretion or membrane proteins from oligo-capped cDNA libraries.

SLC43A2 PROM1 PIGT SIDT2 NUP210 SEC63

3.63e-0443076616303743
Pubmed

Large-scale proteomics and phosphoproteomics of urinary exosomes.

PROM1 DDAH2 SCN11A SMPDL3B PDCD6IP SERINC2 ALDH1L1 FTCD FKBP4

3.69e-04101676919056867
Pubmed

Genetic variants in TPMT and COMT are associated with hearing loss in children receiving cisplatin chemotherapy.

GSTM3 DPYD SULT1B1

4.16e-046676319898482
Pubmed

Aquaporins 8 and 9 as Possible Markers for Adult Murine Lacrimal Gland Cells.

AQP7P3 AQP5

4.86e-041576234540996
Pubmed

Phosphorylation switches protein disulfide isomerase activity to maintain proteostasis and attenuate ER stress.

VMP1 PIGT NCEH1 FKBP4

5.86e-0417476432149426
Pubmed

The transcription factor hepatocyte nuclear factor-6 controls the development of pancreatic ducts in the mouse.

SEC63 AQP5

6.27e-041776216472605
Pubmed

Polyhydramnios in Lrp4 knockout mice with bilateral kidney agenesis: Defects in the pathways of amniotic fluid clearance.

AQP7P3 AQP5

6.27e-041776226847765
Pubmed

Expression patterns of the aquaporin gene family during renal development: influence of genetic variability.

AQP7P3 AQP5

7.87e-041976219367412
Pubmed

Association study between single-nucleotide polymorphisms in 199 drug-related genes and commonly measured quantitative traits of 752 healthy Japanese subjects.

GSTM3 DPYD SULT1B1 ALDH1L1

8.63e-0419376419343046
Pubmed

Molecular Profiling Reveals Involvement of ESCO2 in Intermediate Progenitor Cell Maintenance in the Developing Mouse Cortex.

NCAPD3 DPYD RRM2

9.32e-048776333798452
Pubmed

Ectodysplasin-A signaling is a key integrator in the lacrimal gland-cornea feedback loop.

BMP1 AQP5

9.63e-042176231221639
Pubmed

Nephronophthisis-Related Ciliopathies

WDR19 TMEM67

9.63e-042176227336129
Pubmed

A BioID-Derived Proximity Interactome for SARS-CoV-2 Proteins.

DDAH2 RRM2B EPB41L5 CSGALNACT1 FKBP4 PIGO AKAP12

9.97e-0471976735337019
Pubmed

KLF13 is a genetic modifier of the Holt-Oram syndrome gene TBX5.

BMP1 COL5A1

1.16e-032376228164238
Pubmed

The STUbL RNF4 regulates protein group SUMOylation by targeting the SUMO conjugation machinery.

SLC30A7 WDR3 VMP1 NCAPD3 PIGT NUP210 NCEH1 SEC63 NDUFB3

1.23e-03120376929180619
Pubmed

Glycine N-methyltransferase-/- mice develop chronic hepatitis and glycogen storage disease in the liver.

ALDH1L1 FTCD

1.26e-032476217937387
Pubmed

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.

COL5A1 PACS1 KCNH8 SMPDL3B PDCD6IP NETO1 NUP210 EIF4G3 ADARB1 DNAH14

1.46e-031489761028611215
Pubmed

An unappreciated role for RNA surveillance.

BMP1 FTCD ADARB1

1.47e-0310276314759258
Pubmed

The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.

SLC30A7 GSTM3 WDR3 VMP1 NCAPD3 PIGT EPB41L5 SEC63 EIF4G3 NDUFB3

1.52e-031497761031527615
Pubmed

CTDP1 regulates breast cancer survival and DNA repair through BRCT-specific interactions with FANCI.

NCAPD3 EPB41L5 AKAP12

1.56e-0310476331240132
Pubmed

The basement membrane of hair follicle stem cells is a muscle cell niche.

PROM1 ADRA1A

1.72e-032876221335239
Pubmed

The Catalytically Inactive Mutation of the Ubiquitin-Conjugating Enzyme CDC34 Affects its Stability and Cell Proliferation.

WDR3 PDCD6IP SEC63 FKBP4

1.84e-0323776429564676
Pubmed

Integrating genetic and network analysis to characterize genes related to mouse weight.

SCN7A RRM2

1.84e-032976216934000
Pubmed

Oral facial clefts and gene polymorphisms in metabolism of folate/one-carbon and vitamin A: a pathway-wide association study.

ALDH1L1 FTCD

1.84e-032976219048631
CytobandEnsembl 112 genes in cytogenetic band chr8p21

BMP1 ADRA1A CSGALNACT1

1.49e-03135763chr8p21
CytobandEnsembl 112 genes in cytogenetic band chr1p35

SMPDL3B SERINC2 FGR

1.56e-03137763chr1p35
Cytoband8p21.3

BMP1 CSGALNACT1

1.83e-03387628p21.3
GeneFamilyMannosyl-glycoprotein N-acetylglucosaminyltransferases

MGAT4D MGAT5

2.06e-049442435
GeneFamilyGlycosyl transferases group 1 domain containing|Phosphatidylinositol glycan anchor biosynthesis

PIGT PIGO

1.18e-0321442680
CoexpressionGSE15659_CD45RA_NEG_CD4_TCELL_VS_RESTING_TREG_DN

SLC43A2 PROM1 SULT1B1 RRM2B ZNF596 CFAP44

2.25e-05198756M3552
CoexpressionGSE39556_UNTREATED_VS_3H_POLYIC_INJ_MOUSE_NK_CELL_UP

NCAPD3 SLC25A4 NUP210 IRF4 RRM2 ADARB1

2.31e-05199756M9410
CoexpressionGSE46606_UNSTIM_VS_CD40L_IL2_IL5_3DAY_STIMULATED_IRF4HIGH_SORTED_BCELL_UP

FLII RCC1L PDCD6IP SCN7A ABHD8 PIGO

2.38e-05200756M9831
ToppCelldroplet-Bladder-BLADDER-1m-Epithelial-endothelial_cell|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KCNH8 NETO1 SCN7A NCEH1 FIGN CSGALNACT1

6.33e-07179766c7c74e26bbf86c5326ee38bac7de111d5414f46b
ToppCellImmune_cells-small_pre-B.|Immune_cells / Lineage and Cell class

DDAH2 NCAPD3 RRM2B IRF4 SEC63 AKAP12

1.01e-061947666a440c09805110b1e48e5959a3a9e094c6716bfb
ToppCellAdult-Mesenchymal-matrix_fibroblast_1_cell-D122|Adult / Lineage, Cell type, age group and donor

COL5A1 ADRA1A AGMO SCN7A ALDH1L1 ADARB1

1.04e-06195766aa0add081881d349099d12efca5cdee098038d4e
ToppCellBronchial-NucSeq-Stromal-Fibroblastic-Fibro_alveolar|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

COL5A1 ADRA1A AGMO SCN7A ADARB1 AKAP12

1.21e-06200766e8462395fee0a532d1e7ec7f1795f28c42af6541
ToppCellBronchial-NucSeq-Epithelial-Epi_submucosal-gland-SMG_Mucous|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

PROM1 KCNH8 SLC17A9 ALDH1L1 AQP5 FAM3D

1.21e-06200766ed093626a9cac7531a2bf02f6e345c5e84b8c060
ToppCellfacs-Heart-RA-18m-Myeloid-macrophage|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GSTM3 PROM1 SULT1B1 SERINC2 FAM3D

8.81e-0616376513557be854878abc1bcdab909b49b8292d064145
ToppCellfacs-Heart-RA-18m-Myeloid-macrophage|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GSTM3 PROM1 SULT1B1 SERINC2 FAM3D

8.81e-061637656c1d1646410e785886d2de103b4b12f73e91edff
ToppCelldroplet-Liver-Hepatocytes-21m-Epithelial-Hepatocyte_(Pericentral,_Midlobular,_Periportal)|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BMP1 DPYD NAT8B ALDH1L1 FTCD

9.07e-0616476590afae3cca108ebfb44ff2ec4adcbb8c68a0bdf2
ToppCellfacs-Brain_Myeloid-Striatum-24m-Myeloid-microglial_cell|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CAPN9 DPYD SULT1B1 SERINC2 AQP5

1.08e-05170765626c12b9a51218f72ee32afb5fd5d4b075025d75
ToppCellfacs-Brain_Myeloid-Striatum-24m|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CAPN9 DPYD SULT1B1 SERINC2 AQP5

1.08e-0517076531daac8696ae8c021c0302d3b30dd8194054b3e7
ToppCellfacs-Brain_Myeloid-Striatum-24m-Myeloid-nan|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CAPN9 DPYD SULT1B1 SERINC2 AQP5

1.08e-05170765ca88dc0b7a6960facb7c4d3c0f4795431a0a43d2
ToppCellfacs-Brain_Myeloid-Striatum-24m-Myeloid|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CAPN9 DPYD SULT1B1 SERINC2 AQP5

1.08e-05170765b6882665a27c78a63f3b4a2a8806c8438a98e407
ToppCellCOVID-19-kidney-PCT-S3-2|kidney / Disease (COVID-19 only), tissue and cell type

SULT1B1 ADRA1A SLC17A9 AGMO FTCD

1.21e-051747655aa2fb631505600f37d2b87b02def7be139dc262
ToppCellChildren_(3_yrs)-Immune-B_cell-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

KCNH8 NETO1 NUP210 IRF4 CSGALNACT1

1.42e-0518076540a12eb852373ae3d7c8d9bca376b0ae99f724b3
ToppCellnucseq-Immune-Lymphocytic_B-Lymphocytic_B-B|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

PACS1 MGAT5 KCNH8 NETO1 NUP210

1.46e-051817658d8cc4dae2c8bd5f4b1c159f2a52edc4c9449c86
ToppCell3'-Airway_Nasal_SMG-Epithelial-Epithelial_transtional-secretory-SMG_mucus_secreting_cell-SMG_mucous-SMG_mucous_L.0.6.3.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

GSTM3 PLSCR5 SERINC2 AQP5 FAM3D

1.50e-051827656d7ba2e1f33aaa499a898ed9587197c0ee625e9a
ToppCell5'-GW_trimst-1-SmallIntestine-Neuronal-neurons_B-Branch_B1_(eMN)|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ZMYND15 DPYD KCNH8 SRRM4 MFSD1

1.62e-05185765ef996f4cdbc3971c6c0460d13df64b075ab22154
ToppCell5'-GW_trimst-1-SmallIntestine-Neuronal-neurons_B|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ZMYND15 DPYD KCNH8 SRRM4 MFSD1

1.62e-05185765d51342a3979bd728a80e04126059a3fd8a0dbe3b
ToppCell3'-Airway_Nasal_SMG-Epithelial-Epithelial_transtional-secretory-SMG_mucus_secreting_cell|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

GSTM3 PLSCR5 SERINC2 AQP5 FAM3D

1.62e-05185765d9039770226338fbc3fce92aa229fad96e16db8c
ToppCelldroplet-Lung-30m-Hematologic-myeloid-alveolar_macrophage-proliferating_alveolar_macrophage|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

EPB41L5 NCEH1 CPT1B RRM2 ADARB1

1.62e-05185765b4af9ae4c358b48357cb135b740266e1652d886a
ToppCell3'-Airway_Nasal_SMG-Epithelial-Epithelial_transtional-secretory-SMG_mucus_secreting_cell-SMG_mucous|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

GSTM3 PLSCR5 SERINC2 AQP5 FAM3D

1.62e-05185765b931ab35da10e6e3877071dce9b13fc0da63dc88
ToppCellChildren_(3_yrs)-Immune-B_cell|Children_(3_yrs) / Lineage, Cell type, age group and donor

MGAT5 KCNH8 NETO1 NUP210 IRF4

1.67e-05186765aa576748921a318798b911a611f05319b95e8d5e
ToppCellnormal_Pleural_Fluid-B_lymphocytes-MALT_B_cells|normal_Pleural_Fluid / Location, Cell class and cell subclass

SMPDL3B SLC25A4 SLC17A9 IRF4 RRM2

1.80e-0518976505e8fb483ebb9010cc54b39d78cca960c58c0f01
ToppCellControl-Fibroblasts|Control / group, cell type (main and fine annotations)

COL5A1 ADRA1A SCN7A ADARB1 AKAP12

1.85e-051907653a42a9b98d954685d38a741f44545898d0e3e9ce
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PROM1 AGMO NCEH1 FIGN AKAP12

1.89e-051917651cb02007adb344f17ef73d58890f91298c7cf5a1
ToppCellfacs-Trachea-3m-Mesenchymal-fibroblast-fibroblast_of_trachea-tracheal_fibroblast_l20-25|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

BMP1 COL5A1 DDAH2 NETO1 AKAP12

1.94e-0519276530cefa0990ba1f379f350bfbf994a78db145075e
ToppCellfacs-Trachea-3m-Mesenchymal-fibroblast|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

BMP1 COL5A1 DDAH2 SCN7A AKAP12

1.94e-05192765321850b0f881420c2d57d3e825e365c82fa511ab
ToppCellfacs-Trachea-3m-Mesenchymal-fibroblast-fibroblast_of_trachea|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

BMP1 COL5A1 DDAH2 SCN7A AKAP12

1.94e-05192765cf2765d8bc074f7f9ee864eae632a3b705175842
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SLC43A2 EPB41L5 ALDH1L1 FTCD DNAH14

1.99e-0519376582e8a4c40299ffcdfd5a0da711bb9de6fb8a2eaa
ToppCellfacs-Marrow-B-cells-18m-Lymphocytic-precursor_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RRM2B IRF4 SEC63 AQP5 AKAP12

2.04e-05194765ad1aacff97beb76f4211942676e1d5e84087d44e
ToppCellPCW_10-12-Mesenchymal-Mesenchymal_fibroblastic-mes_immature_adventitial_fibro_(9)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

COL5A1 SCN7A FIGN CSGALNACT1 AKAP12

2.04e-0519476599577a5a631e607b5abe7a1b0d8d6a5eabe50196
ToppCelldroplet-Marrow-nan-3m-Myeloid-granulocytopoietic_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DDAH2 RRM2B IRF4 SEC63 AKAP12

2.04e-051947658ef0b71fef5b84cfd04973f891215333e7035d1d
ToppCellControl-Stromal-Myofibroblast|World / Disease state, Lineage and Cell class

COL5A1 ADRA1A SCN7A ADARB1 AKAP12

2.04e-051947653c2266772c5b56e8e02a461e5193e29588028ee9
ToppCellfacs-Marrow-B-cells-18m-Lymphocytic-pre_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RRM2B IRF4 SEC63 AQP5 AKAP12

2.04e-05194765fdd59b1e036b2d6d8877e1a920a0e56a91a2a882
ToppCell5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Alveolar_fibroblasts-Alveolar_fibroblasts_L.2.1.1.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

GSTM3 COL5A1 ADRA1A SCN7A ADARB1

2.09e-05195765df409f94f4e83be89f7a608058ee07ce3ce3a149
ToppCellCOVID-19_Moderate-Classical_Monocyte|World / disease group, cell group and cell class

SLC43A2 VMP1 DPYD OTOF FGR

2.20e-0519776516cf3939e700aef1e16159f0652ba2dfad287e7a
ToppCellCOVID-19-Myeloid|COVID-19 / group, cell type (main and fine annotations)

SLC43A2 DPYD NCEH1 FGR MFSD1

2.25e-0519876533f0a919188a67d2a876b52c61a1cec2c9747969
ToppCellsystemic_lupus_erythematosus-treated-Myeloid-classical_monocyte-female|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

SLC43A2 VMP1 DPYD FGR MFSD1

2.25e-05198765c79c1738560d78b63dbed5f2f9621dbc1c2363cb
ToppCell15-Airway-Mesenchymal-Mesenchyme_SERPINF1-high|Airway / Age, Tissue, Lineage and Cell class

GSTM3 BMP1 COL5A1 SCN7A AKAP12

2.25e-051987653d76393e72eed59b4dd16130ef5dd1d331ba5711
ToppCellsystemic_lupus_erythematosus-treated-Myeloid-classical_monocyte|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

SLC43A2 VMP1 DPYD FGR MFSD1

2.25e-051987651d1c80569f1e307285ba0ebaf5c72e0b5b538864
ToppCellAdult-Mesenchymal|Adult / Lineage, Cell type, age group and donor

COL5A1 ADRA1A SCN7A ADARB1 AKAP12

2.25e-0519876526e55b409db2a1637c95fae7c54b0abea1ef550c
ToppCellTracheal|World / Cell types per location group and 10X technology with lineage, and cell group designations

PACS1 PROM1 ALDH1L1 AQP5 FAM3D

2.36e-05200765682960e28542a3d6c119047cd0131941932cfdea
ToppCellBronchial-NucSeq-Stromal|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

COL5A1 ADRA1A SCN7A ADARB1 AKAP12

2.36e-05200765389cc775c8419d90fb77cd794376d2160a7bf44e
ToppCellParenchymal-NucSeq-Stromal|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

COL5A1 ADRA1A SCN7A ADARB1 AKAP12

2.36e-05200765cf433f9b43d7db07acaf70e060f8f77c974e72f3
ToppCellBronchial-NucSeq-Stromal-Fibroblastic|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

COL5A1 ADRA1A SCN7A ADARB1 AKAP12

2.36e-05200765cae972324d1dfea6efeaf6013f265c7c6bb48db4
ToppCellmild-HLA-DR+_CD83+_Monocyte|mild / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

SLC43A2 VMP1 DPYD FGR MFSD1

2.36e-052007658a480f487b52938d00b53bf4b18f067353d34419
ToppCellParenchymal-NucSeq-Stromal-Fibroblastic|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

COL5A1 ADRA1A SCN7A ADARB1 AKAP12

2.36e-05200765311fab076f2ceb258e3970eb21e39344b894042a
ToppCellBronchial-NucSeq-Epithelial-Epi_submucosal-gland|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

PROM1 KCNH8 ALDH1L1 AQP5 FAM3D

2.36e-0520076585c0f038bcfb42669dca2b80273b0f8a1421405e
ToppCellfacs-Tongue-nan-18m-Epithelial-basal|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADRA1A GUCY2F GPR141 SVOP

7.71e-05132764cac8c38a398f0185c68bf5b88053010e30475236
ToppCellLPS-antiTNF-Hematopoietic_Meg-Ery-Mes-Epi-like-Erythroid|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

WDR19 PLSCR5 RRM2B NUP210

8.91e-051377648e2fa2ef8becace96a68bb85c002329110902fbb
ToppCellprimary_visual_cortex-Non-neuronal-oligodendrocyte-Oligo-OPC_Pdgfra_Grm5|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

DPYD KCNH8 GUCY2F FIGN

9.42e-05139764a957ea4e581646c76b16b6a7f89579b8c7ac35b6
ToppCellSevere-B_intermediate-14|Severe / disease group and sub_cluster of B and Plasma cells(res = 0.5)

NCEH1 FGR CSGALNACT1 DNAH14

1.02e-04142764f9cbc266fcea19bec504be4f3a28d1173c6b2e3c
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-early_pro-B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DPYD NETO1 GUCY2F AKAP12

1.08e-041447641d05aa08603cba28c0c6511767e434c1f592a3aa
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-early_pro_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DPYD NETO1 GUCY2F AKAP12

1.08e-04144764d3f6f5da56794367ee3776bfd3a9dcf893efe0f0
ToppCelldroplet-Liver-hepatocytes-3m-Epithelial-Hepatocyte_(Pericentral_and_Periportal)|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DPYD NAT8B ALDH1L1 FTCD

1.17e-0414776400619115b9a1ec2b967c2992043b41974ece63c4
ToppCellLPS-IL1RA-Myeloid-Dendritic_cells-Monocytes-Macrophages|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SLC17A9 GPR141 IRF4 NDUFB3

1.23e-04149764a464c0fd54e3c9e1d40d95b49489cb9371dd7c24
ToppCelldroplet-Liver-hepatocytes-3m-Epithelial-nan|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NAT8B ALDH1L1 FTCD FAM3D

1.26e-04150764ee2da4f684add821f2653d5db8eef46cd95c0fda
ToppCelldroplet-Liver-Hepatocytes-24m-Epithelial-nan|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NAT8B SRRM4 ALDH1L1 FTCD

1.33e-04152764c21e2152b0130485659051d8fb7fb4589d1ec997
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Degenerative_Distal_Convoluted_Tubule_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

GSTM3 SLC25A4 SRRM4 NDUFB3

1.36e-0415376498670bbce4a770af244f033cdd2d54db57200ca8
ToppCelldroplet-Liver-Hepatocytes-24m-Epithelial-Hepatocyte_(Pericentral_and_Periportal)|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DPYD NAT8B ALDH1L1 FTCD

1.40e-04154764a5289000597068ee8d559f89bce7bce31f35dd57
ToppCellnormal_Lung-Endothelial_cells-Tumor_ECs|Endothelial_cells / Location, Cell class and cell subclass

ZMYND15 SCN7A RRM2 FIGN

1.40e-04154764afdc385397c7b13c9348eeef95f109f2363057ae
ToppCellfacs-Liver-Hepatocytes|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BMP1 DPYD NAT8B AGMO

1.47e-04156764e2cda3ad4e5f44a80133864c5a38b766afb952ce
ToppCellLPS-IL1RA-Stromal_mesenchymal-Fibroblasts-Pericyte_2|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SIDT2 KCNH8 IRF4 CFAP44

1.54e-041587647f5426585d0d299d2b48e5fcb349950feffdef33
ToppCellTransplant_Alveoli_and_parenchyma-Epithelial-Club|Transplant_Alveoli_and_parenchyma / Tissue, Lineage and Cell class of Lung Cells from 10X

PROM1 AGMO AQP5 FAM3D

1.54e-0415876403281e87780e3bacd089903383c016d03c373bf7
ToppCelldroplet-Liver-LIVER_HEP-30m-Myeloid-myeloid_leukocyte|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SMPDL3B OTOF GPR141 FGR

1.54e-0415876491d265e95156f16459924d3e4dd11c180e164eee
ToppCelldroplet-Liver-Hepatocytes-18m-Epithelial-Hepatocyte_(Pericentral,_Midlobular,_Periportal)|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DPYD NAT8B ALDH1L1 FTCD

1.62e-041607648de1fc75241d9bf2b355afa0e9ef39fea1977177
ToppCellfacs-Liver-Non-hepatocytes-3m-Myeloid-myeloid_leukocyte|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PLSCR5 NUP210 GPR141 FGR

1.62e-04160764237430af14830b38e58da8a4224036e5c6b71c5b
ToppCellP07-Mesenchymal-developing_mesenchymal_cell-mesenchymal_immature_unknown_1|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

PROM1 FGR ADARB1 AKAP12

1.66e-04161764b19f82dd98a3064581793711bb70373f18abecd9
ToppCelllymphoid-B_cell-pro-B|World / Lineage, cell class and subclass

COL5A1 DDAH2 FAM3D AKAP12

1.66e-0416176423138e579f07d5a6f20d41457cb573b4ac95a4ef
ToppCellTransplant_Alveoli_and_parenchyma-Epithelial-Club|Epithelial / Tissue, Lineage and Cell class of Lung Cells from 10X

PROM1 AGMO AQP5 FAM3D

1.70e-04162764fe546c2272a70bb5f08e6e097b9accdb891eda23
ToppCelldroplet-Liver-LIVER_HEP-30m-Myeloid-macrophage/monocyte|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SMPDL3B OTOF GPR141 FGR

1.70e-0416276493bd29c52846c3156b8b0d2e39c552373efdfe93
ToppCelldroplet-Liver-Hepatocytes|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DPYD NAT8B ALDH1L1 FTCD

1.74e-04163764a794540f2d8984f963c08f05175e4bc916fcc224
ToppCellfacs-Brain_Non-Myeloid-Hippocampus-3m-Lymphocytic-T_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL5A1 SMPDL3B SCN7A IRF4

1.74e-041637648028636632c168dc50731d0ebecaf88a70daf81d
ToppCelldroplet-Liver-Hepatocytes-21m|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DPYD NAT8B ALDH1L1 FTCD

1.78e-04164764c9866a289e120be4066e66275c3beb97ba67cca4
ToppCellwk_20-22-Hematologic-Myeloid-HSC/ELP|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

PROM1 SLC17A9 SRRM4 DNAH14

1.78e-041647643c07d8f53511f269540bf032738a4ada35650b18
ToppCelldroplet-Liver-Hepatocytes-21m-Epithelial|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DPYD NAT8B ALDH1L1 FTCD

1.86e-041667644b63ecedf21285974f0d188979fcdced27bf9ef9
ToppCellICU-SEP-Lymphocyte-B-Plasmablast|ICU-SEP / Disease, Lineage and Cell Type

SLC25A4 SLC17A9 IRF4 RRM2

1.86e-0416676498ce43e14133418f676f1c88c001add9e28259a7
ToppCelldroplet-Liver-Hepatocytes-21m-Epithelial-hepatocyte|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DPYD NAT8B ALDH1L1 FTCD

1.86e-04166764d6d29b0dc1ef471b1227495f349963ab37f22ec4
ToppCelldroplet-Lung-30m-Hematologic-myeloid-intermediate_monocyte-intermediate_monocyte_l4|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SMPDL3B GPR141 FGR EIF4G3

1.86e-041667641a3a15d1fc76bb91d832cdc6e3da0a6140b94b75
ToppCelldroplet-Kidney-nan-24m-Myeloid-nan|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SMPDL3B OTOF GPR141 FGR

1.91e-041677642ee1660be117e20f24557522345572d11cbee813
ToppCellfacs-GAT-Fat-18m-Epithelial|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GSTM3 PROM1 SULT1B1 FAM3D

1.95e-04168764d6c8056b7d6b937bb91e6b33beeb1075dce1685c
ToppCellfacs-GAT-Fat-18m-Epithelial-epithelial_cell|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GSTM3 PROM1 SULT1B1 FAM3D

1.95e-041687647102c52bf1b2ba67bb3700932181a2e0a6627711
ToppCell3'-Adult-LargeIntestine-Epithelial-goblet-Goblet_cell|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CAPN9 ALDH1L1 CPT1B FIGN

1.95e-041687642163e6774eb7a3d010422e4d59be5e45b4158329
ToppCelldroplet-Kidney-nan-3m-Epithelial-kidney_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PACS1 SMPDL3B OTOF FGR

1.95e-04168764f45dbcd7753117a3e41e1412bce2100d52fa7fd0
ToppCellCOVID-19-Heart-Neuronal|COVID-19 / Disease (COVID-19 only), tissue and cell type

KCNH8 TLDC2 SCN7A FIGN

1.95e-0416876488c2c574f428c2502b5fe099bd73b0758f668ef6
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_1-Inh_L1-2_VIP_RPL41P3|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ADRA1A KCNH8 PLSCR5 SCN7A

1.95e-041687640a7f81266576409560396356d16989e944865844
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-Adaptive_/_Maladaptive_/_Repairing_Fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

COL5A1 SCN7A IRF4 AKAP12

1.95e-041687644b2d29a7843bf45922038c093ca7ec0600756adc
ToppCelldroplet-Spleen-SPLEEN-1m-Hematologic-proerythroblast|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SMPDL3B OTOF GPR141 FGR

1.95e-04168764f3b7a7df54988de77dcc7066e2fc1feb9c280b13
ToppCellfacs-GAT-Fat-18m-Epithelial-nan|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GSTM3 PROM1 SULT1B1 FAM3D

1.95e-0416876468a2f9fd53b54023241acd1620cf24226f639c1b
ToppCell-Donor_05|World / lung cells shred on cell class, cell subclass, sample id

COL5A1 AGMO SCN7A ADARB1

2.00e-041697648ebe9a88111c53a09c25a7b6a164a0a17880458d
ToppCellfacs-Heart-LA-18m-Myeloid-macrophage|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GSTM3 SULT1B1 SERINC2 FAM3D

2.00e-04169764421fb287c7e439d1870b7950c5e3ca34106e014a
ToppCellfacs-Heart-LA-18m-Myeloid-macrophage|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GSTM3 SULT1B1 SERINC2 FAM3D

2.00e-04169764383639ec4f9d0c6255e0881edca15cdd1980a37c
ToppCell356C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_1.5|CD8+_Cytotoxic_T-cell / Donor, Lineage, Cell class and subclass (all cells)

WDR3 TMEM116 GPR141 CSGALNACT1

2.00e-04169764b66ffc2b2b6bfcc3a6e639d9d31d3de95f4a94e1
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_1-Inh_L1-2_VIP_RPL41P3|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ADRA1A KCNH8 PLSCR5 SCN7A

2.04e-0417076431e3f57673c99f4d8ef30faa9c40e5f7f5bf6460
ToppCelldroplet-Spleen-SPLEEN-1m-Hematologic|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SMPDL3B OTOF GPR141 FGR

2.04e-041707647cb7ad9ab064b6ea452545d145e5b1d4090cd4c1
ToppCelldroplet-Spleen-SPLEEN-1m-Hematologic-nan|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SMPDL3B OTOF GPR141 FGR

2.04e-04170764db7cee7e518debb2cbe9eeae05d47e14b69cb8e3
ToppCellCOVID-19-kidney-Bcells|COVID-19 / Disease (COVID-19 only), tissue and cell type

MGAT5 KCNH8 NETO1 IRF4

2.09e-041717648e8fb79968b1a5c34d1d9cad7f9155fabfdb7cc7
ToppCellCOVID-19-kidney-PEC|kidney / Disease (COVID-19 only), tissue and cell type

PROM1 FIGN ADARB1 AKAP12

2.14e-0417276436a96714a0eb6ac438648135336c9791881ddadb
ToppCellfacs-GAT-Fat-18m|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GSTM3 SULT1B1 FAM3D FKBP4

2.18e-04173764515cb02f3eef86a1ff9a2b4b4f794373ed6633aa
ToppCellCOVID-19-Heart-Neuronal|Heart / Disease (COVID-19 only), tissue and cell type

KCNH8 TLDC2 SCN7A FIGN

2.18e-041737646fb5f9e6536a5d57fd8e6657b494047a2d0bc9c7
Drugcaracemide

GUCY2F RRM2B RRM2

1.86e-0516753CID000054747
DrugAdenosine phosphonoacetic acid

RRM2B RRM2

3.21e-053752CID000448505
DrugAC1N8OVF

RRM2B RRM2

3.21e-053752CID004347182
Drug2'-deoxytoyocamycin

RRM2B RRM2

3.21e-053752CID000204132
Drug2'-chloro-2'-dudp

RRM2B RRM2

3.21e-053752CID003082518
Drug1-amino-3-hydroxyguanidine

RRM2B RRM2

3.21e-053752CID009571038
DrugBild 1351

RRM2B RRM2

3.21e-053752CID005478827
Drug3,4-dihydroxybenzaldoxime

RRM2B RRM2

3.21e-053752CID005388593
Drughydroxyguanidine sulfate

RRM2B RRM2

3.21e-053752CID000080667
DrugNSC-137029

RRM2B RRM2

3.21e-053752CID000421633
DrugBild 1357

RRM2B RRM2

3.21e-053752CID000515298
Drug2'-azido-2'-deoxycytidine 5'-diphosphate

RRM2B RRM2

3.21e-053752CID000170963
DrugAC1LAKEY

RRM2B RRM2

3.21e-053752CID000515340
DrugVal-Val-Asn-Asp-Leu

RRM2B RRM2

3.21e-053752CID000515343
Drugdial-CDP

RRM2B RRM2

3.21e-053752CID005487791
Drugcyclo(Sar-Sar

RRM2B RRM2

3.21e-053752CID000078761
DrugBumetanide [28395-03-1]; Down 200; 11uM; PC3; HT_HG-U133A

BMP1 COL5A1 PACS1 NUP210 ABHD8 PIGO

4.50e-051957565117_DN
Drug9-deoxy-9-methylene-16,16-dimethyl Prostaglandin E2; Up 200; 10uM; PC3; HT_HG-U133A

BMP1 PACS1 SMPDL3B NUP210 ADARB1 AKAP12

4.50e-051957567557_UP
Drug(R) -Naproxen sodium salt [26159-34-2]; Up 200; 15.8uM; MCF7; HT_HG-U133A

WDR19 CAPN9 SCN11A SIDT2 IRF4 ADARB1

5.04e-051997566794_UP
Drug2-formylpyridine thiosemicarbazonato copper(II

RRM2B RRM2

6.40e-054752CID009576822
Drug4-nitro-benzohydrazide

RRM2B RRM2

6.40e-054752CID003693744
DrugBPYTA

RRM2B RRM2

6.40e-054752CID003034633
Drug2-formylpyridine thiosemicarbazone

RRM2B RRM2

6.40e-054752CID001638752
Drugp-propoxyphenol

RRM2B RRM2

6.40e-054752CID000029352
DrugDacisteine

RRM2B RRM2

6.40e-054752CID000065690
Drug2'-azido-2'-deoxyuridine

RRM2B RRM2

6.40e-054752CID000168629
DrugAC1NQVLK

RRM2B RRM2

1.06e-045752CID002732427
DrugA1110U

RRM2B RRM2

1.06e-045752CID003006964
Drug2-methylene-3-furanone

RRM2B RRM2

1.06e-045752CID000124504
Drug348U87

RRM2B RRM2

1.06e-045752CID003006985
Drug2-hydroxy-1-naphthylaldehyde benzoyl hydrazone

RRM2B RRM2

1.06e-045752CID005384003
Drugp-butoxyphenol

RRM2B RRM2

1.06e-045752CID000031233
DrugmdGuo

RRM2B RRM2

1.06e-045752CID000126596
Drugbruceine

RRM2B RRM2

1.06e-045752CID000122785
DrugMdAdo

RRM2B RRM2

1.06e-045752CID000175972
DrugN-hydroxy-N'-methylurea

RRM2B RRM2

1.06e-045752CID000096412
DrugCitrusinine-I

RRM2B RRM2

1.06e-045752CID005487772
Drugdisulfate

SULT1B1 SLC25A4 FKBP4

1.18e-0429753CID000062682
DrugDimethylnitrosamine

COL5A1 PROM1 DPYD NAT8B SLC25A4 MRO RRM2B FTCD FGR FKBP4 AKAP12

1.19e-048657511ctd:D004128
DrugEndor

RRM2B RRM2 ADARB1

1.59e-0432753CID000061044
DrugVF 122

RRM2B RRM2

1.59e-046752CID000100590
Diseaseproteinuria (implicated_via_orthology)

TMEM67 MGAT5 EPB41L5

5.39e-0530723DOID:576 (implicated_via_orthology)
DiseaseProgressive External Ophthalmoplegia with Mitochondrial DNA Deletions, Autosomal Dominant, 1

SLC25A4 RRM2B

5.84e-055722C1834846
Diseasefeeling nervous measurement

DDAH2 DPYD IRF4 DNAH14

6.22e-0587724EFO_0009597
DiseaseLiver Cirrhosis, Experimental

SLC43A2 COL5A1 MGAT5 SLC25A4 MRO ALDH1L1 FTCD FGR CSGALNACT1

1.09e-04774729C0023893
Diseasegeneralized epilepsy with febrile seizures plus 2 (implicated_via_orthology)

SCN11A SCN7A

2.61e-0410722DOID:0111294 (implicated_via_orthology)
DiseaseDravet syndrome (implicated_via_orthology)

SCN11A SCN7A

2.61e-0410722DOID:0080422 (implicated_via_orthology)
Diseaseresponse to cisplatin, platinum measurement

NCEH1 FIGN ADARB1

2.99e-0453723EFO_0010154, GO_0072718
DiseaseMitochondrial Myopathies

SLC25A4 RRM2B

3.18e-0411722C0162670
Diseasegeneralized epilepsy with febrile seizures plus (implicated_via_orthology)

SCN11A SCN7A

3.81e-0412722DOID:0060170 (implicated_via_orthology)
DiseaseNephronophthisis

WDR19 TMEM67

4.50e-0413722C0687120
Diseaseprimary autosomal recessive microcephaly (is_implicated_in)

NCAPD3 PDCD6IP

6.89e-0416722DOID:0070296 (is_implicated_in)
Diseasespinal stenosis

MGAT4D AGMO

7.80e-0417722EFO_0007490
DiseaseColorectal Carcinoma

GSTM3 PROM1 DPYD ALDH1L1 RRM2 PIGO AKAP12

1.62e-03702727C0009402
Diseaseobesity (implicated_via_orthology)

CAPN9 GSTM3 FLII ADARB1

1.91e-03215724DOID:9970 (implicated_via_orthology)
DiseaseHodgkins lymphoma, multiple myeloma, chronic lymphocytic leukemia

IRF4 SERINC2

2.13e-0328722EFO_0000095, EFO_0000183, EFO_0001378

Protein segments in the cluster

PeptideGeneStartEntry
IKKETGFWRDFGFGM

CSGALNACT1

411

Q8TDX6
WATPGFFNKFSVIFK

AGMO

286

Q6ZNB7
ETGSTFKKFFTQGWA

AKAP12

291

Q02952
FKPSETVFKIVFWLG

ADRA1A

301

P35348
AGWGFALTKTFSLDK

DPYD

566

Q12882
WLKFVSDGSINKAGF

BMP1

526

P13497
IKFWEMAFTFTGLKL

CFAP44

296

Q96MT7
AWSFLKAGFARQGAK

ABHD8

306

Q96I13
TLIFVFFGLGSALKW

AQP5

21

P55064
FKWGFAAFVVAVGAE

NDUFB3

71

O43676
GVFEWDAFAKGTKAL

PGK2

341

P07205
FAALTNKGELFVWGK

RCC1L

406

Q96I51
IKSSGRFLWIKFFAD

NETO1

126

Q8TDF5
LLFVFGGSHWFKQKI

GPR141

281

Q7Z602
LAFAKEKSFGWPSFI

NUP210

1731

Q8TEM1
TFFKIAGSGLVAKWL

FIGN

546

Q5HY92
SSKKWGSFFIDSVLG

NT5DC1

371

Q5TFE4
KQLGFRDSWVFIGAK

FAM3D

171

Q96BQ1
GWLTFTFSLQKKFES

FLII

996

Q13045
LFGRFTIKSDVWSFG

FGR

431

P09769
FKAWALFKGKFREGI

IRF4

71

Q15306
SQKLGFFLVTFGFIW

MGAT5

11

Q09328
IKFSWLGFDHKITGK

SLC43A2

246

Q8N370
FTFIAGWGKLVFSDG

AQP7P3

236

A6NL99
WLSNESIALFKKGAF

SMPDL3B

161

Q92485
LTFTWKDAFDKGSLF

PDCD6IP

91

Q8WUM4
GKISKYWSGFVNDVF

PLSCR5

216

A0PG75
ALNFIIVSFGKKSAW

NCEH1

61

Q6PIU2
AVSWFKGKELNLVFG

MFSD1

161

Q9H3U5
LGKFSWFAGEKLTFV

GSTM3

146

P21266
FGQLAAFAGRKWKKF

MRO

156

Q9BYG7
VKGALGRVFSLNFWK

OR6Q1

301

Q8NGQ2
FTAFIKAGLGAWVEK

ADARB1

716

P78563
WFFIEFSMLGFIGKL

MGAT4D

281

A6NG13
FFVKSLANKTSDWLG

PACS1

641

Q6VY07
VFEGDTKIGLFFWPK

EPB41L5

256

Q9HCM4
VWLKKFSLGDFGDLK

GUCY2F

571

P51841
GSWFSEFKRGKLLSY

COL5A1

1701

P20908
KLFVFAFTWAFGGAL

DNAH14

1766

Q0VDD8
KFSFDLGKGEVIKAW

FKBP4

76

Q02790
FTGREFFVGLSKWTN

DDAH2

131

O95865
SGNGKLEFDEFKVFW

CAPN9

576

O14815
KGVALKSVTAFFTWL

EIF4G3

1561

O43432
RWFDKSFTLISFKNG

CPT1B

451

Q92523
WGATATGARKFLIAF

FTCD

171

O95954
FFTGEKSSDIFVRGW

OTOF

1751

Q9HC10
GTGLYWLIFFKAQKS

TMEM67

581

Q5HYA8
AIGFGKFQWKLSVLT

SVOP

76

Q8N4V2
FGKGNTAFWIVFSII

SIDT2

626

Q8NBJ9
GFSFKEKIFIALAWM

SLC9B1P1

191

A6NJY1
LNLFWFGIGKATVFL

PROM1

791

O43490
GWNKKEAGIVLSSFF

SLC17A9

56

Q9BYT1
SFLLWSKVGSFLAVG

WDR19

101

Q8NEZ3
EKFLTGKVAYGSWFT

SULT1B1

161

O43704
WTLIHGDKKGGFSIF

ALDH1L1

121

O75891
GAKAFFKGAWSNVLR

SLC25A4

266

P12235
GGKWTFFLSATKLEE

CCDC54

256

Q8NEL0
VKWKGSLFFRFVSTL

NCAPD3

1011

P42695
VFFSGSFAAIFWLKK

RRM2B

196

Q7LG56
SKKFGKIFSDWLSFN

ZNF596

141

Q8TC21
FDAFITGQGKKDWSL

PIGT

246

Q969N2
FSGSFASIFWLKKRG

RRM2

236

P31350
LFEKFWRGTFKAVAT

SRRM4

11

A7MD48
KFVKSTGFLGSEQWA

TMEM116

116

Q8NCL8
AGWALFLFLAYKVSK

SEC63

81

Q9UGP8
FNLFGKISGWFRSIL

SLC30A7

16

Q8NEW0
WKVFAPKFIFEAVGF

PIGO

1041

Q8TEQ8
VKLFARGVWAGSFSF

SCN7A

161

Q01118
VLKWVAFGFGKYFTS

SCN11A

1106

Q9UI33
KVFKWTGSNSFFVKG

TLDC2

146

A0PJX2
FVTGGADKSVKFWDF

WDR3

511

Q9UNX4
VIGFNSGFALKDTWL

ZMYND15

611

Q9H091
GFWFFKFLILVGLTV

SERINC2

131

Q96SA4
WTFFGATLIGKAIIK

VMP1

286

Q96GC9
KFILLHFSTFKAGWD

KCNH8

211

Q96L42
LGFKKTGQSFFHVWA

NAT8B

191

Q9UHF3