Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionenzyme regulator activity

AGAP4 AGAP6 AGAP5 USP6NL PHACTR2 EED AGAP11 PHACTR4 PHACTR3 AGAP9 AGAP7P PHACTR1

2.53e-0914182112GO:0030234
GeneOntologyMolecularFunctionenzyme activator activity

AGAP4 AGAP6 AGAP5 USP6NL EED AGAP11 PHACTR4 AGAP9 AGAP7P

8.71e-09656219GO:0008047
GeneOntologyMolecularFunctionGTPase activator activity

AGAP4 AGAP6 AGAP5 USP6NL AGAP11 AGAP9 AGAP7P

9.49e-09279217GO:0005096
GeneOntologyMolecularFunctionprotein phosphatase inhibitor activity

PHACTR2 PHACTR4 PHACTR3 PHACTR1

2.02e-0750214GO:0004864
GeneOntologyMolecularFunctionphosphatase inhibitor activity

PHACTR2 PHACTR4 PHACTR3 PHACTR1

2.76e-0754214GO:0019212
GeneOntologyMolecularFunctionGTPase regulator activity

AGAP4 AGAP6 AGAP5 USP6NL AGAP11 AGAP9 AGAP7P

5.57e-07507217GO:0030695
GeneOntologyMolecularFunctionnucleoside-triphosphatase regulator activity

AGAP4 AGAP6 AGAP5 USP6NL AGAP11 AGAP9 AGAP7P

5.57e-07507217GO:0060589
GeneOntologyMolecularFunctionGTPase activity

AGAP4 AGAP6 AGAP5 AGAP11 AGAP9 AGAP7P

1.04e-06341216GO:0003924
GeneOntologyMolecularFunctionmolecular function activator activity

AGAP4 AGAP6 AGAP5 USP6NL EED AGAP11 PHACTR4 AGAP9 AGAP7P

1.89e-061233219GO:0140677
GeneOntologyMolecularFunctionGTP binding

AGAP4 AGAP6 AGAP5 AGAP11 AGAP9 AGAP7P

2.51e-06397216GO:0005525
GeneOntologyMolecularFunctionprotein phosphatase regulator activity

PHACTR2 PHACTR4 PHACTR3 PHACTR1

3.32e-06100214GO:0019888
GeneOntologyMolecularFunctionguanyl ribonucleotide binding

AGAP4 AGAP6 AGAP5 AGAP11 AGAP9 AGAP7P

4.47e-06439216GO:0032561
GeneOntologyMolecularFunctionguanyl nucleotide binding

AGAP4 AGAP6 AGAP5 AGAP11 AGAP9 AGAP7P

4.47e-06439216GO:0019001
GeneOntologyMolecularFunctionphosphatase regulator activity

PHACTR2 PHACTR4 PHACTR3 PHACTR1

5.40e-06113214GO:0019208
GeneOntologyMolecularFunctionphospholipid binding

AGAP4 AGAP6 AGAP5 AGAP11 AGAP9 AGAP7P

1.59e-05548216GO:0005543
GeneOntologyMolecularFunctionribonucleoside triphosphate phosphatase activity

AGAP4 AGAP6 AGAP5 AGAP11 AGAP9 AGAP7P

1.10e-04775216GO:0017111
GeneOntologyMolecularFunctionpyrophosphatase activity

AGAP4 AGAP6 AGAP5 AGAP11 AGAP9 AGAP7P

1.70e-04839216GO:0016462
GeneOntologyMolecularFunctionhydrolase activity, acting on acid anhydrides

AGAP4 AGAP6 AGAP5 AGAP11 AGAP9 AGAP7P

1.72e-04840216GO:0016817
GeneOntologyMolecularFunctionhydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides

AGAP4 AGAP6 AGAP5 AGAP11 AGAP9 AGAP7P

1.72e-04840216GO:0016818
GeneOntologyMolecularFunctionlipid binding

AGAP4 AGAP6 AGAP5 AGAP11 AGAP9 AGAP7P

4.13e-04988216GO:0008289
GeneOntologyMolecularFunctionprotein phosphatase 1 binding

PHACTR4 PHACTR1

6.14e-0435212GO:0008157
GeneOntologyMolecularFunctionenzyme inhibitor activity

PHACTR2 PHACTR4 PHACTR3 PHACTR1

9.91e-04435214GO:0004857
GeneOntologyMolecularFunctionactin binding

PHACTR2 PHACTR4 PHACTR3 PHACTR1

1.42e-03479214GO:0003779
GeneOntologyMolecularFunctionmolecular function inhibitor activity

PHACTR2 PHACTR4 PHACTR3 PHACTR1

3.14e-03596214GO:0140678
GeneOntologyBiologicalProcessactivation of GTPase activity

AGAP4 AGAP6 AGAP5 USP6NL AGAP11 AGAP9 AGAP7P

1.04e-11109217GO:0090630
GeneOntologyBiologicalProcesspositive regulation of GTPase activity

AGAP4 AGAP6 AGAP5 USP6NL AGAP11 AGAP9 AGAP7P

3.00e-09244217GO:0043547
GeneOntologyBiologicalProcessregulation of GTPase activity

AGAP4 AGAP6 AGAP5 USP6NL AGAP11 AGAP9 AGAP7P

2.68e-08335217GO:0043087
GeneOntologyBiologicalProcesspositive regulation of hydrolase activity

AGAP4 AGAP6 AGAP5 USP6NL AGAP11 AGAP9 AGAP7P

4.03e-07499217GO:0051345
GeneOntologyBiologicalProcesspositive regulation of catalytic activity

AGAP4 AGAP6 AGAP5 USP6NL AGAP11 PHACTR4 AGAP9 AGAP7P

4.22e-061028218GO:0043085
GeneOntologyBiologicalProcessregulation of hydrolase activity

AGAP4 AGAP6 AGAP5 USP6NL AGAP11 AGAP9 AGAP7P

1.70e-05878217GO:0051336
GeneOntologyBiologicalProcesspositive regulation of molecular function

AGAP4 AGAP6 AGAP5 USP6NL AGAP11 PHACTR4 AGAP9 AGAP7P

4.71e-051430218GO:0044093
HumanPhenoHypoplastic iliac wing

COL2A1 EED

1.07e-043132HP:0002866
HumanPhenoHypoplastic ilia

COL2A1 EED

4.48e-046332HP:0000946
HumanPhenoAbnormal iliac wing morphology

COL2A1 EED

5.22e-046832HP:0011867
HumanPhenoBroad thumb

COL2A1 EED

9.16e-049032HP:0011304
HumanPhenoCoxa valga

COL2A1 EED

9.57e-049232HP:0002673
HumanPhenoAbnormal ilium morphology

COL2A1 EED

1.22e-0310432HP:0002867
HumanPhenoRound face

COL2A1 EED

1.68e-0312232HP:0000311
HumanPhenoBroad phalanx

COL2A1 EED

2.47e-0314832HP:0006009
HumanPhenoBroad phalanges of the hand

COL2A1 EED

2.47e-0314832HP:0009768
HumanPhenoBroad finger

COL2A1 EED

2.67e-0315432HP:0001500
HumanPhenoBroad long bones

COL2A1 EED

2.77e-0315732HP:0005622
HumanPhenoAbnormal femoral neck morphology

COL2A1 EED

2.88e-0316032HP:0003367
HumanPhenoLow-set ears

COL2A1 EED PHACTR1

3.32e-0376133HP:0000369
HumanPhenoFlared metaphysis

COL2A1 EED

4.09e-0319132HP:0003015
MousePhenofused cornea and lens

AGAP4 AGAP6 AGAP5 AGAP11 AGAP9 AGAP7P

1.59e-1324176MP:0001307
MousePhenoabnormal lens development

AGAP4 AGAP6 AGAP5 AGAP11 AGAP9 AGAP7P

2.92e-1078176MP:0005545
MousePhenoabsent pinna reflex

AGAP4 AGAP6 AGAP5 AGAP11 AGAP9 AGAP7P

6.57e-1089176MP:0006358
MousePhenoabnormal eye development

COL2A1 AGAP4 AGAP6 AGAP5 AGAP11 PHACTR4 ZFC3H1 AGAP9 AGAP7P

1.22e-09482179MP:0001286
MousePhenoabnormal pinna reflex

AGAP4 AGAP6 AGAP5 AGAP11 AGAP9 AGAP7P

1.42e-09101176MP:0001485
MousePhenoabnormal anterior uvea morphology

COL2A1 AGAP4 AGAP6 AGAP5 AGAP11 AGAP9 AGAP7P

1.84e-09199177MP:0005194
MousePhenopersistence of hyaloid vascular system

AGAP4 AGAP6 AGAP5 AGAP11 ZFC3H1 AGAP9 AGAP7P

4.06e-09223177MP:0001289
MousePhenoincreased circulating potassium level

AGAP4 AGAP6 AGAP5 AGAP11 AGAP9 AGAP7P

4.25e-09121176MP:0005627
MousePhenoabnormal uvea morphology

COL2A1 AGAP4 AGAP6 AGAP5 AGAP11 AGAP9 AGAP7P

6.97e-09241177MP:0005197
MousePhenoabnormal snout morphology

COL2A1 AGAP4 AGAP6 AGAP5 AGAP11 AGAP9 AGAP7P

1.09e-08257177MP:0000443
MousePhenocornea opacity

AGAP4 AGAP6 AGAP5 AGAP11 AGAP9 AGAP7P

2.20e-08159176MP:0001314
MousePhenoabnormal circulating potassium level

AGAP4 AGAP6 AGAP5 AGAP11 AGAP9 AGAP7P

3.40e-08171176MP:0002668
MousePhenoabnormal skin coloration

AGAP4 AGAP6 AGAP5 AGAP11 AGAP9 AGAP7P

4.93e-08182176MP:0011239
MousePhenoabnormal iris morphology

AGAP4 AGAP6 AGAP5 AGAP11 AGAP9 AGAP7P

6.78e-08192176MP:0001322
MousePhenoabnormal potassium level

AGAP4 AGAP6 AGAP5 AGAP11 AGAP9 AGAP7P

7.66e-08196176MP:0020887
MousePhenoabnormal potassium ion homeostasis

AGAP4 AGAP6 AGAP5 AGAP11 AGAP9 AGAP7P

8.14e-08198176MP:0011978
MousePhenoabnormal vitreous body morphology

AGAP4 AGAP6 AGAP5 AGAP11 ZFC3H1 AGAP9 AGAP7P

3.64e-07429177MP:0002699
MousePhenoabnormal tooth morphology

AGAP4 AGAP6 AGAP5 AGAP11 AGAP9 AGAP7P

1.32e-06318176MP:0002100
MousePhenoabnormal dental arch morphology

AGAP4 AGAP6 AGAP5 AGAP11 AGAP9 AGAP7P

1.35e-06319176MP:0030254
MousePhenoabnormal jaw morphology

COL2A1 AGAP4 AGAP6 AGAP5 AGAP11 AGAP9 AGAP7P

1.51e-06530177MP:0000454
MousePhenoabnormal cornea morphology

AGAP4 AGAP6 AGAP5 AGAP11 AGAP9 AGAP7P

3.00e-06366176MP:0001312
MousePhenoabnormal viscerocranium morphology

COL2A1 AGAP4 AGAP6 AGAP5 AGAP11 AGAP9 AGAP7P

3.20e-06593177MP:0005274
MousePhenoabnormal hearing physiology

COL2A1 AGAP4 AGAP6 AGAP5 AGAP11 AGAP9 AGAP7P

5.48e-06643177MP:0001963
MousePhenoabnormal mouth morphology

COL2A1 AGAP4 AGAP6 AGAP5 AGAP11 AGAP9 AGAP7P

7.19e-06670177MP:0000452
MousePhenoabnormal ear physiology

COL2A1 AGAP4 AGAP6 AGAP5 AGAP11 AGAP9 AGAP7P

8.23e-06684177MP:0003878
MousePhenoabnormal lens morphology

COL2A1 AGAP4 AGAP6 AGAP5 AGAP11 AGAP9 AGAP7P

9.50e-06699177MP:0001303
MousePhenocataract

AGAP4 AGAP6 AGAP5 AGAP11 AGAP9 AGAP7P

1.74e-05497176MP:0001304
MousePhenoincreased circulating alkaline phosphatase level

AGAP4 AGAP6 AGAP5 AGAP11 AGAP9 AGAP7P

2.40e-05526176MP:0002968
MousePhenoabnormal cranium morphology

COL2A1 AGAP4 AGAP6 AGAP5 AGAP11 AGAP9 AGAP7P

2.55e-05813177MP:0000438
MousePhenoabnormal craniofacial bone morphology

COL2A1 AGAP4 AGAP6 AGAP5 AGAP11 AGAP9 AGAP7P

2.85e-05827177MP:0002116
MousePhenoabnormal auditory brainstem response

AGAP4 AGAP6 AGAP5 AGAP11 AGAP9 AGAP7P

4.00e-05576176MP:0004738
MousePhenoabnormal hearing electrophysiology

AGAP4 AGAP6 AGAP5 AGAP11 AGAP9 AGAP7P

4.75e-05594176MP:0006335
MousePhenohearing/vestibular/ear phenotype

COL2A1 AGAP4 AGAP6 AGAP5 AGAP11 AGAP9 AGAP7P

5.10e-05905177MP:0005377
MousePhenoabnormal facial morphology

COL2A1 AGAP4 AGAP6 AGAP5 AGAP11 AGAP9 AGAP7P

5.28e-05910177MP:0003743
MousePhenoincreased circulating mineral level

AGAP4 AGAP6 AGAP5 AGAP11 AGAP9 AGAP7P

6.38e-05626176MP:0014547
MousePhenoabnormal circulating alkaline phosphatase level

AGAP4 AGAP6 AGAP5 AGAP11 AGAP9 AGAP7P

7.15e-05639176MP:0000202
MousePhenoincreased mineral level

AGAP4 AGAP6 AGAP5 AGAP11 AGAP9 AGAP7P

9.16e-05668176MP:0014535
MousePhenoabnormal anterior eye segment morphology

COL2A1 AGAP4 AGAP6 AGAP5 AGAP11 AGAP9 AGAP7P

1.94e-041117177MP:0005193
MousePhenoabnormal head morphology

COL2A1 AGAP4 AGAP6 AGAP5 AGAP11 AGAP9 AGAP7P

1.97e-041120177MP:0000432
MousePhenoabnormal reflex

AGAP4 AGAP6 AGAP5 PHLDB2 AGAP11 AGAP9 AGAP7P

4.84e-041294177MP:0001961
MousePhenocraniofacial phenotype

COL2A1 AGAP4 AGAP6 AGAP5 AGAP11 AGAP9 AGAP7P

6.93e-041372177MP:0005382
MousePhenoabnormal craniofacial morphology

COL2A1 AGAP4 AGAP6 AGAP5 AGAP11 AGAP9 AGAP7P

6.93e-041372177MP:0000428
MousePhenoabnormal circulating enzyme level

AGAP4 AGAP6 AGAP5 AGAP11 AGAP9 AGAP7P PHACTR1

6.93e-041372177MP:0001570
MousePhenoabnormal circulating mineral level

AGAP4 AGAP6 AGAP5 AGAP11 AGAP9 AGAP7P

7.47e-04982176MP:0006357
MousePhenoabnormal enzyme/coenzyme level

AGAP4 AGAP6 AGAP5 AGAP11 AGAP9 AGAP7P PHACTR1

9.73e-041451177MP:0005319
MousePhenoabnormal skin morphology

AGAP4 AGAP6 AGAP5 AGAP11 AGAP9 AGAP7P PHACTR1

9.89e-041455177MP:0002060
MousePhenoabnormal axial skeleton morphology

COL2A1 AGAP4 AGAP6 AGAP5 AGAP11 AGAP9 AGAP7P

1.00e-031458177MP:0002114
MousePhenoabnormal sensory capabilities/reflexes/nociception

AGAP4 AGAP6 AGAP5 PHLDB2 AGAP11 AGAP9 AGAP7P

1.12e-031486177MP:0002067
MousePhenoabnormal mineral level

AGAP4 AGAP6 AGAP5 AGAP11 AGAP9 AGAP7P

1.15e-031066176MP:0000192
MousePhenoabnormal mineral homeostasis

AGAP4 AGAP6 AGAP5 AGAP11 AGAP9 AGAP7P

1.21e-031076176MP:0005636
MousePhenoincreased circulating enzyme level

AGAP4 AGAP6 AGAP5 AGAP11 AGAP9 AGAP7P

1.64e-031140176MP:0014450
MousePhenoincreased enzyme/coenzyme level

AGAP4 AGAP6 AGAP5 AGAP11 AGAP9 AGAP7P

1.70e-031148176MP:0014448
MousePhenodisproportionate dwarf

COL2A1 EED

2.14e-0357172MP:0002427
MousePhenoabnormal ion homeostasis

AGAP4 AGAP6 AGAP5 AGAP11 AGAP9 AGAP7P

2.45e-031232176MP:0001765
MousePhenoincreased circulating protein level

AGAP4 AGAP6 AGAP5 AGAP11 AGAP9 AGAP7P

5.25e-031433176MP:0014501
DomainArfGap

AGAP4 AGAP6 AGAP5 AGAP11 AGAP9 AGAP7P

1.48e-1329186SM00105
DomainArfGap

AGAP4 AGAP6 AGAP5 AGAP11 AGAP9 AGAP7P

1.48e-1329186PF01412
DomainArfGAP

AGAP4 AGAP6 AGAP5 AGAP11 AGAP9 AGAP7P

1.48e-1329186IPR001164
DomainARFGAP

AGAP4 AGAP6 AGAP5 AGAP11 AGAP9 AGAP7P

1.48e-1329186PS50115
DomainRPEL_repeat

PHACTR2 PHACTR4 PHACTR3 PHACTR1

2.11e-117184IPR004018
DomainRPEL

PHACTR2 PHACTR4 PHACTR3 PHACTR1

2.11e-117184SM00707
DomainRPEL

PHACTR2 PHACTR4 PHACTR3 PHACTR1

2.11e-117184PS51073
DomainRPEL

PHACTR2 PHACTR4 PHACTR3 PHACTR1

2.11e-117184PF02755
DomainPH

AGAP4 AGAP6 AGAP5 PHLDB2 AGAP11 AGAP9 AGAP7P

4.15e-09278187SM00233
DomainPH_DOMAIN

AGAP4 AGAP6 AGAP5 PHLDB2 AGAP11 AGAP9 AGAP7P

4.26e-09279187PS50003
DomainPH_domain

AGAP4 AGAP6 AGAP5 PHLDB2 AGAP11 AGAP9 AGAP7P

4.36e-09280187IPR001849
DomainPH_dom-like

AGAP4 AGAP6 AGAP5 PHLDB2 AGAP11 AGAP9 AGAP7P

7.83e-08426187IPR011993
DomainAnkyrin_rpt-contain_dom

AGAP4 AGAP6 AGAP5 AGAP11 AGAP9 AGAP7P

9.65e-08254186IPR020683
DomainANK_REP_REGION

AGAP4 AGAP6 AGAP5 AGAP11 AGAP9 AGAP7P

9.65e-08254186PS50297
Domain-

AGAP4 AGAP6 AGAP5 PHLDB2 AGAP11 AGAP9

1.22e-063911862.30.29.30
Domain-

AGAP4 AGAP6 AGAP5 AGAP11 AGAP9

2.95e-062481851.25.40.20
DomainANK

AGAP4 AGAP6 AGAP5 AGAP11 AGAP7P

3.13e-06251185SM00248
DomainANK_REPEAT

AGAP4 AGAP6 AGAP5 AGAP11 AGAP7P

3.25e-06253185PS50088
DomainAnkyrin_rpt

AGAP4 AGAP6 AGAP5 AGAP11 AGAP7P

3.86e-06262185IPR002110
DomainAnk_2

AGAP4 AGAP6 AGAP5 AGAP11

4.60e-05215184PF12796
DomainPH

AGAP4 PHLDB2 AGAP11 AGAP7P

5.89e-05229184PF00169
DomainAnk

AGAP4 AGAP11 AGAP7P

1.28e-03228183PF00023
PathwayREACTOME_RETROGRADE_TRANSPORT_AT_THE_TRANS_GOLGI_NETWORK

USP6NL VAMP3

2.07e-044572MM15355
PathwayREACTOME_RETROGRADE_TRANSPORT_AT_THE_TRANS_GOLGI_NETWORK

USP6NL VAMP3

2.46e-044972M27653
Pubmed

GGAPs, a new family of bifunctional GTP-binding and GTPase-activating proteins.

AGAP4 AGAP6 AGAP5 AGAP11 AGAP9 AGAP7P

1.85e-18921612640130
Pubmed

AGAP1/AP-3-dependent endocytic recycling of M5 muscarinic receptors promotes dopamine release.

AGAP4 AGAP6 AGAP5 AGAP11 AGAP9 AGAP7P

4.63e-181021620664521
Pubmed

AGAP1, a novel binding partner of nitric oxide-sensitive guanylyl cyclase.

AGAP4 AGAP6 AGAP5 AGAP11 AGAP9 AGAP7P

1.02e-171121615381706
Pubmed

The Endosome Localized Arf-GAP AGAP1 Modulates Dendritic Spine Morphology Downstream of the Neurodevelopmental Disorder Factor Dysbindin.

AGAP4 AGAP6 AGAP5 AGAP11 AGAP9 AGAP7P

3.78e-171321627713690
Pubmed

GTP-binding protein-like domain of AGAP1 is protein binding site that allosterically regulates ArfGAP protein catalytic activity.

AGAP4 AGAP6 AGAP5 AGAP11 AGAP9 AGAP7P

6.61e-171421622453919
Pubmed

Different expression patterns of Phactr family members in normal and injured mouse brain.

PHACTR2 PHACTR4 PHACTR3 PHACTR1

3.43e-12721422766235
Pubmed

Phactrs 1-4: A family of protein phosphatase 1 and actin regulatory proteins.

PHACTR2 PHACTR4 PHACTR3 PHACTR1

3.43e-12721415107502
Pubmed

Synaptic GAP and GEF Complexes Cluster Proteins Essential for GTP Signaling.

AGAP4 AGAP6 AGAP5 AGAP11 AGAP9 AGAP7P PHACTR1

2.20e-1028121728706196
Pubmed

The TRIM9/TRIM67 neuronal interactome reveals novel activators of morphogenesis.

AGAP4 AGAP6 AGAP5 AGAP11 AGAP9 AGAP7P

2.84e-0921821633378226
Pubmed

Oncogenic functions of protein kinase D2 and D3 in regulating multiple cancer-related pathways in breast cancer.

AGAP4 AGAP6 AGAP5 AGAP11 AGAP9

7.38e-0911621530652415
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

AGAP4 AGAP6 AGAP5 USP6NL AGAP11 AGAP9 AGAP7P

1.75e-0852921714621295
Pubmed

Identification of new ciliary signaling pathways in the brain and insights into neurological disorders.

AGAP4 AGAP6 AGAP5 AGAP11 AGAP9 AGAP7P

1.12e-0740521638187761
Pubmed

Ex vivo Quantitative Proteomic Analysis of Serotonin Transporter Interactome: Network Impact of the SERT Ala56 Coding Variant.

AGAP4 AGAP6 AGAP5 AGAP11 AGAP9 AGAP7P

1.60e-0743021632581705
Pubmed

Characterization of an exchangeable gene trap using pU-17 carrying a stop codon-beta geo cassette.

AGAP4 AGAP6 AGAP5 AGAP11 AGAP9 AGAP7P

5.81e-0753621615840001
Pubmed

Exchangeable gene trap using the Cre/mutated lox system.

AGAP4 AGAP6 AGAP5 AGAP11 AGAP9 AGAP7P

5.94e-0753821610512203
Pubmed

Scapinin, a putative protein phosphatase-1 regulatory subunit associated with the nuclear nonchromatin structure.

PHACTR4 PHACTR3

1.04e-06321212925532
Pubmed

A Multipronged Unbiased Strategy Guides the Development of an Anti-EGFR/EPHA2-Bispecific Antibody for Combination Cancer Therapy.

USP6NL PHACTR2 PHLDB2 PHACTR4 VAMP3

4.40e-0642121536976175
Pubmed

Mouse screen reveals multiple new genes underlying mouse and human hearing loss.

AGAP4 AGAP6 AGAP5 AGAP11 AGAP9 AGAP7P VAMP3

5.45e-06124221730973865
Pubmed

E-cadherin interactome complexity and robustness resolved by quantitative proteomics.

USP6NL PHACTR2 PHLDB2 PHACTR4 VAMP3

1.82e-0556521525468996
Pubmed

Phactr4 regulates neural tube and optic fissure closure by controlling PP1-, Rb-, and E2F1-regulated cell-cycle progression.

PHACTR4 PHACTR1

5.90e-051921217609112
Pubmed

Pbx1/Pbx2 govern axial skeletal development by controlling Polycomb and Hox in mesoderm and Pax1/Pax9 in sclerotome.

COL2A1 EED

8.72e-052321218691704
Pubmed

In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.

FAM186A PDIA6 PHACTR2 ZFC3H1 CCDC148 VAMP3

1.59e-04144221635575683
Pubmed

The functional landscape of Hsp27 reveals new cellular processes such as DNA repair and alternative splicing and proposes novel anticancer targets.

AGAP4 AGAP5 AGAP7P

3.26e-0422521325277244
Pubmed

The Functional Proximal Proteome of Oncogenic Ras Includes mTORC2.

USP6NL PHLDB2 PHACTR4 VAMP3

3.40e-0456921430639242
InteractionPRKD2 interactions

AGAP4 AGAP6 AGAP5 AGAP11 AGAP9

4.06e-06254205int:PRKD2
CytobandEnsembl 112 genes in cytogenetic band chr10q11

AGAP4 AGAP6 AGAP9 AGAP7P

1.54e-06188214chr10q11
Cytoband10q11.23

AGAP6 AGAP7P

1.04e-043321210q11.23
Cytoband10q11.22

AGAP4 AGAP9

1.62e-044121210q11.22
CytobandEnsembl 112 genes in cytogenetic band chr12q13

COL2A1 FAM186A

1.58e-02423212chr12q13
GeneFamilyArfGAPs

AGAP4 AGAP6 AGAP5 AGAP11 AGAP9 AGAP7P

2.79e-1333176395
GeneFamilyPhosphatase and actin regulators

PHACTR2 PHACTR4 PHACTR3 PHACTR1

5.35e-134174679
GeneFamilyX-linked mental retardation|Rho GTPase activating proteins|BAR-PH domain containing

AGAP4 AGAP6 AGAP5 AGAP11 AGAP9

2.36e-12171751291
GeneFamilyPleckstrin homology domain containing|Rho guanine nucleotide exchange factors|C2 domain containing

AGAP4 AGAP6 AGAP5 PHLDB2 AGAP9 AGAP7P

2.27e-08206176682
GeneFamilyAnkyrin repeat domain containing

AGAP4 AGAP6 AGAP5 AGAP11 AGAP9 AGAP7P

5.91e-08242176403
GeneFamilyArmadillo repeat containing|Protein phosphatase 1 regulatory subunits

PHACTR4 PHACTR3

1.23e-02181172694
CoexpressionTHEODOROU_MAMMARY_TUMORIGENESIS

AGAP4 AGAP6 AGAP5 AGAP11 AGAP9 AGAP7P

1.97e-1337206MM1121
CoexpressionGAUSSMANN_MLL_AF4_FUSION_TARGETS_F_DN

AGAP4 AGAP6 AGAP5 AGAP11 AGAP9 AGAP7P

5.97e-1344206MM485
CoexpressionKARLSSON_TGFB1_TARGETS_DN

AGAP4 AGAP6 AGAP5 AGAP11 AGAP9 AGAP7P

8.45e-09209206MM1058
CoexpressionCHYLA_CBFA2T3_TARGETS_DN

AGAP4 AGAP6 AGAP5 AGAP11 AGAP9 AGAP7P

3.32e-08263206MM1295
ToppCellAT1-AT2_cells-IPF_01|World / lung cells shred on cell class, cell subclass, sample id

COL2A1 PHLDB2 PHACTR3

5.81e-0516221357d627259d27f39885bf416d74bcb6656db6e27b
ToppCell5'-GW_trimst-1.5-LargeIntestine-Neuronal-Glial_immature-Glia_1_(DHH+)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

COL2A1 FAM186A PHACTR3

7.06e-05173213789ab8b2709f4b8728e3733bc72744e9d92ea5ea
ToppCellPBMC-Convalescent-Lymphocyte-B-B_cell-B_intermediate-B_intermediate-14|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

AGAP6 USP6NL PHACTR1

7.31e-0517521387e557f7508c88b2087db5d57e77d5e2c92ca083
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_4|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PHACTR2 PHLDB2 PHACTR1

7.31e-0517521306af6629766e2054e6995e8cdb3907658fec49d3
ToppCell3'-GW_trimst-1-LargeIntestine-Neuronal-Glial_immature-Glia_1_(DHH+)|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

COL2A1 PHACTR3 PHACTR1

8.34e-05183213547b1fb9f9940cfc8d6e351d96acc0da44def57e
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_1-D062|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

PHLDB2 PHACTR3 PHACTR1

8.48e-0518421329c95b814a0b1ad8734ed68b77df29c08594e5ec
ToppCell343B-Epithelial_cells-Epithelial-I_(AT1)-|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

PHACTR2 PHLDB2 PHACTR3

8.48e-05184213c7073d1b2c4fdb154d87678b92a0629c02116972
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Macula_Densa_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PHACTR3 CCDC148 PHACTR1

8.48e-051842138fd8bd3d28d0ee6f0ef1f14e354d8eaf63a8081b
ToppCell343B-Epithelial_cells-Epithelial-I_(AT1)|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

PHACTR2 PHLDB2 PHACTR3

8.48e-051842131ed558a88215b248431c524ea16f13d9022ae98c
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Macula_Densa_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PHACTR3 CCDC148 PHACTR1

9.18e-05189213e059be2965cca70ff5576df055d0af1775b76e00
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PHACTR3 CCDC148 PHACTR1

9.32e-051902133fc9e18c7441c0ae8cda65753cc42d0520f4e116
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PHACTR3 CCDC148 PHACTR1

9.47e-051912135a67ff17fb4b9eff641176dff07830c9cd73754e
ToppCellLAM-Epithelial-AT1|Epithelial / Condition, Lineage and Cell class

PHACTR2 PHLDB2 PHACTR3

9.47e-051912133457e15d1e9b36a78363d46b320c4ec46b40290a
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PHACTR3 CCDC148 PHACTR1

9.47e-0519121355ab2854a02cdcfc395e49870ccb7290b5e5471d
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PHACTR4 PHACTR3 PHACTR1

1.01e-04195213938b31dbf1674ee6fd0123bc88391ddcaf151217
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PHACTR4 PHACTR3 PHACTR1

1.01e-04195213d39e9e6544f49e677ebe528c6fe60b99a3630e30
ToppCellCOVID-19-kidney-TAL|kidney / Disease (COVID-19 only), tissue and cell type

PHACTR3 CCDC148 PHACTR1

1.02e-0419621304f5eb206ed3016a737609a3ebac0c1fcabb94ef
ToppCellPosterior_cortex-Macroglia-OLIGODENDROCYTE-O1-Tfr-Oligodendrocyte.Tfr.Il33_(Il33)-|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

COL2A1 FAM186A

4.92e-04702128ee9c9c78eec9dc0cec364ee7c9bc6f34d37de76
ToppCellPosterior_cortex-Macroglia-OLIGODENDROCYTE-O1-Tfr|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

COL2A1 FAM186A

4.92e-0470212b159435487b90331d2d276f182fc8aedf88d612c
ToppCellPosterior_cortex-Macroglia-OLIGODENDROCYTE-O1-Tfr-Oligodendrocyte.Tfr.Il33_(Il33)|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

COL2A1 FAM186A

4.92e-04702127e09547b73789d789c3c464689f7998445830238
ToppCellPosterior_cortex-Macroglia-OLIGODENDROCYTE-O1|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

COL2A1 FAM186A

4.92e-0470212b486f7fe68743e3385809cfd64512da2f31074df
ToppCellPosterior_cortex-Neuronal-Excitatory-eN1(Slc17a7)-eN1_2-Fezf2-Excitatory_Neuron.Slc17a7-Slc17a6.Fezf2-3110035E14Rik_(Layer_5,_Retrosplenial_cortex_(RSG)_and_Subiculum,_Tshz2+)|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

COL2A1 FAM186A

5.49e-047421283b762542508f9d6407e4b0087d70bea81a8fc7d
ToppCell368C-Epithelial_cells-Epithelial-B_(AT2)-|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

AGAP4 AGAP6

1.14e-031072125bae4b3aede9bcbf7e88414e3453973cc8b0c3e7
ToppCell368C-Epithelial_cells-Epithelial-B_(AT2)|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

AGAP4 AGAP6

1.14e-03107212410b37beffaf637a2a64c9d0ce7baf81f4bc667c
ToppCellsaliva-Severe-critical_progression_d12-22_with-steroid-Myeloid-Monocytic-Classical_Monocyte|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

ZFC3H1 PHACTR1

1.41e-03119212e6f1b9f29dc8fe6b6132c7885234c385159da393
ToppCell356C-Fibroblasts-Fibroblast-E|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

AGAP6 FAM186A

1.83e-03136212edfd453c9a650d69d05a5a3ab15f7df56349fa86
ToppCell356C-Fibroblasts-Fibroblast-E-|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

AGAP6 FAM186A

1.83e-0313621203e4e2353c23ceffde35b2d0aadd15299e3db09f
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-NK_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL2A1 PHACTR3

1.94e-031402127ca49bd7ba9381e75c10f888775df17e5d46804d
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-NK_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL2A1 PHACTR3

1.94e-031402121a31bc33d5723b9bc528cc0047ca5f4c80531c7a
ToppCellPBMC-Severe-Lymphocyte-B-B_cell-B_naive-B_naive-9|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

USP6NL PHACTR1

2.22e-03150212d9931507257c64ead4a53786e6822f51962c6015
ToppCellfacs-Marrow-Granulocytes-24m-Lymphocytic-NK_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PHACTR3 CCDC148

2.22e-03150212a3a4710820a244116a26204f40e7113a1e7236c5
ToppCellfacs-Marrow-Granulocytes-24m-Lymphocytic-NK_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PHACTR3 CCDC148

2.22e-0315021213dcd519dacf08d5852aa3e029e0a3308de07321
ToppCellPND01-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Deuterosomal-Deuterosomal_mature|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

TEX50 CCDC148

2.25e-03151212633ed52dd3b4cf1e87432cf0a1ca187d7b204e83
ToppCellPND01-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Deuterosomal|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

TEX50 CCDC148

2.25e-03151212e335dad89e0a44cdd302b9653154ba5d1ee5fe1a
ToppCellfacs-Spleen-nan-24m-Lymphocytic-NK_cell|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PHACTR3 CCDC148

2.34e-03154212bd283c2367afb99294e7576a0c0167eb7c69ad6b
ToppCell10x5'-Liver-Lymphocytic_T_CD4-Tfh|Liver / Manually curated celltypes from each tissue

AGAP4 CCDC148

2.40e-0315621285bc34ff507f9a66c6e3ba7a3ffd5416d0073ccf
ToppCellfacs-MAT-Fat-18m-Lymphocytic-NK_cell|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PHACTR3 CCDC148

2.43e-03157212e6846ffd1bb18bf0469bc6d49ab6cf3533d9cde6
ToppCellPBMC-Control-Myeloid-cDC-cDC-cDC_1|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

AGAP11 PHACTR1

2.46e-03158212216b3f482daa2d0d7fcaf5a8559e3ccbdb8e110d
ToppCell3'_v3-lymph-node_spleen-Lymphocytic_B-ABC_aged-B_naive|lymph-node_spleen / Manually curated celltypes from each tissue

USP6NL PHACTR1

2.46e-031582127098847804dd90fa1dd74536e4e90f989b630fe4
ToppCellPBMC-Control-Myeloid-cDC-cDC-cDC_1|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

AGAP11 PHACTR1

2.46e-031582129712bb8b1bacb8a38c99a22bc2babec5d5160e2a
ToppCelldroplet-Lung-nan-3m-Lymphocytic-Proliferating_NK|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SPOUT1 PHACTR3

2.46e-03158212ee8ce3cd202807df692b28bb1a81827d49d73862
ToppCellTransplant_Alveoli_and_parenchyma-Epithelial-Type_1_alveolar|Epithelial / Tissue, Lineage and Cell class of Lung Cells from 10X

PHLDB2 PHACTR3

2.52e-0316021258ed3a074932ccc951e07868dfdc61b99ae1cc2b
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Medullary_Thick_Ascending_Limb_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

CCDC148 PHACTR1

2.52e-0316021203b88dc7ad41c6ae443cab7e77ec666340bf432e
ToppCell356C-Lymphocytic-NK_cells-NK_cell_A2|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

AGAP5 PHACTR1

2.56e-031612128ec923c230a7a3cce5edf2a736b3a00d607c698a
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD8_c01-LEF1|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

SPOUT1 AGAP5

2.56e-031612125fba13f0aa5002f7eefe219e2c6a07e163f1a50d
ToppCellAT1_cells-IPF_01|World / lung cells shred on cell class, cell subclass, sample id

PHLDB2 PHACTR3

2.59e-03162212ae2ba4f21f6f6c512006fa531d670b88be7c04c9
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Macula_Densa_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

PHACTR3 CCDC148

2.59e-03162212373513f9d0e5007b2e10a8b78d4909dcce9e3b62
ToppCellnormal_Lymph_Node-Myeloid_cells-Monocytes|Myeloid_cells / Location, Cell class and cell subclass

CCDC148 PHACTR1

2.62e-031632127d7f18e5c99be125e95bc180823430291b770d05
ToppCell10x5'-bone_marrow-Lymphocytic_B-ABC_aged-B_memory|bone_marrow / Manually curated celltypes from each tissue

AGAP4 USP6NL

2.65e-03164212746833f74095c0f25ce76baf1069f1848c231933
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Glutamatergic_Excit-Glut_C_(NP)-Glut_NP_L5/6_FEZF2|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

USP6NL PHLDB2

2.71e-0316621201544c851588f1cde05d6700c3d1167f70a0fbd5
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Glutamatergic_Excit-Glut_C_(NP)|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

USP6NL PHLDB2

2.71e-03166212c22a97353f7eb084f768c13d7767a80b30f05043
ToppCelltumor_Lymph_Node_/_Brain-Myeloid_cells-Pleural_Mac|Myeloid_cells / Location, Cell class and cell subclass

AGAP4 AGAP9

2.78e-031682128697b40b2ec2cce68ef3beb4792eb3eff29be053
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_5-Exc_L4-5_RORB_HNRNPA1P46|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PHACTR2 PHLDB2

2.78e-031682129adb91ae87a009db7ed83e0d3ab964acc38708f1
ToppCellfacs-Heart-RA-18m-Endothelial-endothelial_cell_of_endocardium|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PHACTR2 PHLDB2

2.78e-0316821206dc5b2d356d3a9454b10bba6f3b9ead2a0a7d46
ToppCellfacs-Heart-RA-18m-Endothelial-endocardial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PHACTR2 PHLDB2

2.78e-031682121002f058a340763e3d8de0bd1f0547a903526ec6
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_C_(NP)|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

USP6NL PHLDB2

2.81e-03169212bddb28a8b9afbe4a68f082e82caf96a6666fc674
ToppCell3'-Pediatric_IBD-SmallIntestine-Epithelial-Tuft-related-Microfold_cell|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract

COL2A1 CCDC148

2.81e-03169212a54a8494c1feff29d77ab4737fcfabc84ace5c94
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_C_(NP)-Glut_NP_L5/6_FEZF2|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

USP6NL PHLDB2

2.81e-031692125ce46bac8e767feec7ecdc61689de225c49bd3f7
ToppCellControl-Epithelial_cells-ECM-high_epithelial|Control / group, cell type (main and fine annotations)

PHLDB2 PHACTR1

2.84e-03170212e2023d66e70983c87dacbd6181d3426488d1fc57
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Glutamatergic_Excit-Glut_C_(NP)-Glut_NP_L5/6_FEZF2-Exc_L5-6_FEZF2_RSAD2|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

USP6NL PHLDB2

2.84e-0317021263dfbc4746717132dc81b6bac868c7498fc96283
ToppCellPBMC-Convalescent-Lymphocyte-B-B_cell-B_naive-B_naive-5|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

USP6NL PHACTR1

2.88e-0317121223b3120706bb9c20b9214fe3760c6d7a84f1e749
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_4|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PHLDB2 PHACTR1

2.88e-03171212f648789e6aefe508bb748401bf9b3cd830fb0ddf
ToppCelldroplet-Liver-Hepatocytes-21m-Myeloid-Kupffer_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PHACTR2 PHACTR1

2.91e-03172212574ebdf36e45222bcd907cd2c2ee7ff50ed4573a
ToppCelldroplet-Liver-Hepatocytes-21m-Myeloid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PHACTR2 PHACTR1

2.91e-031722121627fa7035b0e0bbc82a1c0f000d8231254c680a
ToppCellfacs-Trachea-nan-24m-Mesenchymal-chondrocyte|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL2A1 TEX50

2.94e-031732122226505610af1becc253d0a5550627144ef0ed6b
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_C_(IT_L4_RORB)-Exc_L4-5_RORB_ASCL1|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PHACTR2 PHLDB2

2.94e-031732122e35bf2b5534a289d93a09faae660f665c131062
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_4-Exc_L4-5_RORB_LCN15|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PHACTR2 PHLDB2

2.94e-031732125aa4d45a01d2d09eff8b4deb32bd91ab2471210a
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_4|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PHLDB2 PHACTR1

2.94e-03173212ee972d9cc68755926512fd3bbe1267098c67cd94
ToppCell3'-Child09-12-SmallIntestine-Hematopoietic-Plasma_cells-IgM_plasma_cell|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PDIA6 PHACTR1

2.94e-0317321277e2b2e66c89984769f2800bdeeab42f9cf9fc46
ToppCell3'-GW_trimst-1.5-LargeIntestine-Neuronal-Glial_immature-Glia_1_(DHH+)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

COL2A1 PHACTR3

2.94e-03173212922356a5b4c84607318ac24d7caa2e235b72b066
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_4-Exc_L4-5_RORB_LCN15|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PHACTR2 PHLDB2

2.98e-031742122947e5906b172d149412fa4e77476fce4ea695d2
ToppCellControl-Epithelial_cells-AT1|Control / group, cell type (main and fine annotations)

PHLDB2 PHACTR1

2.98e-03174212548d7f2b958a2bfd2c95eb049ceaab55a559c77d
ToppCell3'-GW_trimst-1.5-SmallIntestine-Neuronal-Glial_immature-Glia_1_(DHH+)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

COL2A1 PHACTR3

2.98e-03174212667035a11b68745fa8446d6c68214713be42710f
ToppCell5'-GW_trimst-2-LymphNode-Endothelial-blood_vessel_EC-Fetal_venous_EC|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

USP6NL CCDC148

2.98e-031742126b5ff1cc5fe6705f7ea70b5a892dfbf91e32288d
ToppCellfacs-Trachea-24m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

COL2A1 TEX50

3.01e-03175212f1394aacc8a94ca555dd19aaed5a18da99c6bf40
ToppCellfacs-Trachea-24m-Mesenchymal-myofibroblast|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

COL2A1 TEX50

3.01e-031752127bf1194d93fbe2dbf9d953e0a32b2a6d88251ed1
ToppCellAT1-AT2_cells-Donor_06|World / lung cells shred on cell class, cell subclass, sample id

PHLDB2 PHACTR3

3.01e-03175212bdd85ba280648a0283c1984662a34c7b840f64dd
ToppCellNS-moderate-d_0-4-Epithelial-Ionocyte|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

PHLDB2 PHACTR3

3.01e-03175212a1e0a15c69211d6db2edeb101476f0f6e08b90c8
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_C_(NP)-Glut_NP_L5/6_FEZF2-Exc_L5-6_FEZF2_MYBPHL|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

USP6NL PHLDB2

3.01e-03175212bc6bd8c3ce956245ef4db91af9501649d5c09478
ToppCelldroplet-Liver-Hepatocytes-21m-Myeloid-Kupffer_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PHACTR2 PHACTR1

3.04e-031762128e89471f838ea81235256cc2470f1c12c9b75f8a
ToppCellfacs-Trachea-24m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l34|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

COL2A1 TEX50

3.04e-0317621277c3da2eaa072a6baefb5087fd07ec18c5e271cd
ToppCellTCGA-Cervix-Primary_Tumor-Cervical_Carcinoma-Non-keratinizing_Cervical_Squamous_Cell_Carcinoma|TCGA-Cervix / Sample_Type by Project: Shred V9

PHLDB2 VAMP3

3.04e-031762128513c2a05a34453a16bbcf1c11cb34c580133e47
ToppCelldroplet-Marrow-BM-1m-Lymphocytic-plasma_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL2A1 CCDC148

3.08e-0317721226bad614560609d318bfc9c235a698bca4e1c22c
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_4|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PHLDB2 PHACTR1

3.08e-031772127e799333307448c6a94d1f33dbc59c543336f45e
ToppCellControl-Epithelial_alveolar-AT_1-Differentiating_AT1|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PHLDB2 PHACTR1

3.08e-031772129af14a056eb6d88c6f11b09f6d4c0d3448d647d5
ToppCellPBMC-Convalescent-Lymphocyte-B-B_cell-B_naive-B_naive-11|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

USP6NL PHACTR1

3.08e-031772123535575686c9700ab72700aae6f2070ebbb50044
ToppCellmetastatic_Brain-T/NK_cells-Exhausted_Tfh|T/NK_cells / Location, Cell class and cell subclass

AGAP4 AGAP6

3.11e-031782129a3581a0158dfa5a1cc942f8c532afb5e38b272a
ToppCellPBMC-Convalescent-Lymphocyte-B-B_cell-B_intermediate-B_intermediate-0|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

USP6NL PHACTR1

3.11e-03178212be1d991c5a0a5be22f14f57d34ee1330f1a12963
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_5-Exc_L4-5_RORB_HNRNPA1P46|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PHACTR2 PHLDB2

3.11e-03178212b863fc85d2449f25e6cea289459a7bb1f89583fd
ToppCellwk_08-11-Epithelial-PNS-Late_Schwann|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

PHACTR3 PHACTR1

3.11e-03178212a7301c0bba03d10feacc02e3f929d9a9235fd25b
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_5-Exc_L4-5_RORB_HNRNPA1P46|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PHACTR2 PHLDB2

3.15e-03179212c815eb9f760fe4ca7a5e49beb224659f0b864f22
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_5-Exc_L4-5_RORB_HNRNPA1P46|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PHACTR2 PHLDB2

3.15e-0317921253e700494d251ec5649b2dea5fc7d5aeeeed572b
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_1-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

PHLDB2 PHACTR1

3.15e-031792124f6ca313b78aa93557937a046c44dcf8bcc9963c
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_4-Exc_L4-5_RORB_RPL31P31|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PHLDB2 PHACTR1

3.15e-03179212d3d3a9afaac28fa4f2c448c73d79bcbbbea088d7
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_4-Exc_L4-5_RORB_RPL31P31|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PHLDB2 PHACTR1

3.15e-03179212b35a7f8115c997c390201da01d7cb10b10769aec
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_C_(IT_L4_RORB)-Exc_L4_RORB_CCDC168|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PHACTR2 PHLDB2

3.18e-03180212a407376209d80177bf7fc4200219030c83cb5f14
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_5-Exc_L4-5_RORB_HNRNPA1P46|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PHACTR2 PHLDB2

3.18e-031802128923a42a6db9c6e9f3ce2ca9530e620dfea700ba
ToppCellnormal-na-Lymphocytic_NK-T_mait-male|normal / PBMC cell types (v2) per disease, treatment status, and sex

PDIA6 PHACTR2

3.18e-03180212e66a8a61b3576ac37de7c559d16d4ed4f7a2fc78
ToppCell3'-GW_trimst-2-LargeIntestine-Neuronal-Glial_immature-Glia_1_(DHH+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

COL2A1 PHACTR3

3.18e-03180212b294f9db1e2ff51c94cde64fae4c2b057c0030a1
ToppCellRV|World / Chamber and Cluster_Paper

PHACTR3 PHACTR1

3.21e-03181212bbe1e6e59d8889bd37d6e8303116cbdcafca7236
Drugradicicol, diheterospora chlamydosporia; Up 200; 0.1uM; HL60; HT_HG-U133A

USP6NL PHACTR2 EED PHACTR1

1.55e-051772042679_UP
Diseasecerebral palsy (implicated_via_orthology)

AGAP4 AGAP6 AGAP5 AGAP11 AGAP9 AGAP7P

8.87e-1810206DOID:1969 (implicated_via_orthology)
Diseaseblood nickel measurement

PHLDB2 PHACTR3

2.97e-03120202EFO_0007583
Diseaseangina pectoris

PHACTR2 PHACTR1

3.22e-03125202EFO_0003913

Protein segments in the cluster

PeptideGeneStartEntry
KLKRKYWWKNCKMWA

VAMP3

66

Q15836
LLKRSGKWLKTWKKK

AGAP4

266

Q96P64
GKWLKTWKKKYVTLC

AGAP4

271

Q96P64
KKIKKYWAKKKQKWQ

CCDC148

416

Q8NFR7
RSGKWLKTWKKKYVT

AGAP11

131

Q8TF27
KRSGKWLKTWKKKYV

AGAP9

336

Q5VTM2
LLKRSGKWLKTWKKK

AGAP6

266

Q5VW22
GKWLKTWKKKYVTLC

AGAP6

271

Q5VW22
VPKKNWWSSKSKEKK

COL2A1

1331

P02458
KSWGKGKWKSKKCKY

EED

66

O75530
TIGKIFKPWKWRKKK

PHACTR2

36

O75167
FKPWKWRKKKTSDKF

PHACTR2

41

O75167
GKIFKPWKWRKKKSS

PHACTR4

41

Q8IZ21
PWKWRKKKSSDKFKE

PHACTR4

46

Q8IZ21
KPWKWRKKKSEKFKH

PHACTR1

121

Q9C0D0
LLKRSGKWLKTWKKK

AGAP7P

266

Q5VUJ5
GKWLKTWKKKYVTLC

AGAP7P

271

Q5VUJ5
KKKILSRGTLWKSWK

FAM186A

191

A6NE01
WRKWKQQKKEEKKKW

SPOUT1

21

Q5T280
LKLADKYKKKMWGWL

PDIA6

321

Q15084
KPWKWRKKKNEKLKQ

PHACTR3

76

Q96KR7
IKMGGKIKTWKKRWF

PHLDB2

1151

Q86SQ0
KRSGKWLKTWKKKYV

AGAP5

291

A6NIR3
KWLKMLKGWEKYKNT

USP6NL

76

Q92738
HYLWKKWKKHQKKLK

TEX50

96

A0A1B0GTY4
TYKDKRKWKPKFWRK

ZFC3H1

1281

O60293