Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	ubiquitin-protein transferase activity	RNF214 RNF130 BIRC8 TRIM69 TRIM51 RNF20 NFX1 BIRC3 RFFL DTX3L MDM4 RNF128	1.57e-07	473	74	12	GO:0004842
GeneOntologyMolecularFunction	ubiquitin-like protein transferase activity	RNF214 RNF130 BIRC8 TRIM69 TRIM51 RNF20 NFX1 BIRC3 RFFL DTX3L MDM4 RNF128	3.68e-07	512	74	12	GO:0019787
GeneOntologyMolecularFunction	aminoacyltransferase activity	RNF214 RNF130 BIRC8 TRIM69 TRIM51 RNF20 NFX1 BIRC3 RFFL DTX3L MDM4 RNF128	5.52e-07	532	74	12	GO:0016755
GeneOntologyMolecularFunction	ubiquitin protein ligase activity	RNF130 BIRC8 TRIM69 TRIM51 RNF20 NFX1 BIRC3 RFFL DTX3L RNF128	1.11e-06	372	74	10	GO:0061630
GeneOntologyMolecularFunction	ubiquitin-like protein ligase activity	RNF130 BIRC8 TRIM69 TRIM51 RNF20 NFX1 BIRC3 RFFL DTX3L RNF128	2.04e-06	398	74	10	GO:0061659
GeneOntologyMolecularFunction	acyltransferase activity	RNF214 RNF130 BIRC8 TRIM69 TRIM51 RNF20 NFX1 BIRC3 RFFL DTX3L MDM4 RNF128	2.58e-05	775	74	12	GO:0016746
GeneOntologyMolecularFunction	phosphatidylethanolamine flippase activity	ATP11B ATP11A	2.81e-04	7	74	2	GO:0090555
GeneOntologyMolecularFunction	transition metal ion binding	ZNF675 TTF2 SETDB1 DPYD TRIM51 TRIM42 LACC1 ABCE1 ZNF330 CXXC4 NFX1 ALB MDM4	3.88e-04	1189	74	13	GO:0046914
GeneOntologyMolecularFunction	phosphatidylserine floppase activity	ATP11B ATP11A	4.80e-04	9	74	2	GO:0090556
GeneOntologyMolecularFunction	extracellular matrix constituent conferring elasticity	FBN1 FBN2	8.73e-04	12	74	2	GO:0030023
GeneOntologyMolecularFunction	histone ubiquitin ligase activity	RNF20 DTX3L	8.73e-04	12	74	2	GO:0140852
GeneOntologyMolecularFunction	intramembrane lipid transporter activity	ATP11B ATP11A ANO3	8.95e-04	51	74	3	GO:0140303
GeneOntologyMolecularFunction	pyridoxal phosphate binding	SDSL GAD2 ALB	1.18e-03	56	74	3	GO:0030170
GeneOntologyMolecularFunction	structural molecule activity conferring elasticity	FBN1 FBN2	1.20e-03	14	74	2	GO:0097493
GeneOntologyMolecularFunction	glycerophospholipid flippase activity	ATP11B ATP11A	1.20e-03	14	74	2	GO:0140333
GeneOntologyMolecularFunction	vitamin B6 binding	SDSL GAD2 ALB	1.24e-03	57	74	3	GO:0070279
GeneOntologyMolecularFunction	floppase activity	ATP11B ATP11A	1.57e-03	16	74	2	GO:0140328
GeneOntologyMolecularFunction	zinc ion binding	ZNF675 TTF2 SETDB1 TRIM51 TRIM42 ZNF330 CXXC4 NFX1 ALB MDM4	1.60e-03	891	74	10	GO:0008270
GeneOntologyMolecularFunction	flippase activity	ATP11B ATP11A	1.78e-03	17	74	2	GO:0140327
GeneOntologyMolecularFunction	intracellularly calcium-gated channel activity	TTYH2 ANO3	2.47e-03	20	74	2	GO:0141147
GeneOntologyMolecularFunction	intracellularly calcium-gated chloride channel activity	TTYH2 ANO3	2.47e-03	20	74	2	GO:0005229
GeneOntologyMolecularFunction	phospholipid transporter activity	ATP11B ATP11A ANO3	2.62e-03	74	74	3	GO:0005548
GeneOntologyMolecularFunction	vitamin binding	SDSL GAD2 GC ALB	3.02e-03	161	74	4	GO:0019842
GeneOntologyMolecularFunction	cysteine-type endopeptidase inhibitor activity involved in apoptotic process	BIRC8 BIRC3	3.55e-03	24	74	2	GO:0043027
GeneOntologyMolecularFunction	ATPase-coupled intramembrane lipid transporter activity	ATP11B ATP11A	4.81e-03	28	74	2	GO:0140326
GeneOntologyBiologicalProcess	regulation of brain-derived neurotrophic factor-activated receptor activity	FAM72D FAM72C FAM72A FAM72B	1.36e-10	4	72	4	GO:0031551
GeneOntologyBiologicalProcess	negative regulation of brain-derived neurotrophic factor receptor signaling pathway	FAM72D FAM72C FAM72A FAM72B	6.80e-10	5	72	4	GO:0031549
GeneOntologyBiologicalProcess	regulation of brain-derived neurotrophic factor receptor signaling pathway	FAM72D FAM72C FAM72A FAM72B	4.74e-09	7	72	4	GO:0031548
GeneOntologyBiologicalProcess	brain-derived neurotrophic factor receptor signaling pathway	FAM72D FAM72C FAM72A FAM72B	1.33e-07	14	72	4	GO:0031547
GeneOntologyBiologicalProcess	protein ubiquitination	RNF130 BIRC8 TRIM69 TRIM51 TRIM42 RNF20 NFX1 BIRC3 RFFL MINAR1 N4BP1 DTX3L MDM4 RNF128	6.77e-07	811	72	14	GO:0016567
GeneOntologyBiologicalProcess	negative regulation of catalytic activity	ZNF675 FAM72D BIRC8 FAM72C ABCE1 FAM72A WFDC6 PALM RFFL WFDC8 DTX3L FAM72B	1.33e-06	615	72	12	GO:0043086
GeneOntologyBiologicalProcess	protein modification by small protein conjugation	RNF130 BIRC8 TRIM69 TRIM51 TRIM42 RNF20 NFX1 BIRC3 RFFL MINAR1 N4BP1 DTX3L MDM4 RNF128	2.11e-06	893	72	14	GO:0032446
GeneOntologyBiologicalProcess	negative regulation of protein tyrosine kinase activity	FAM72D FAM72C FAM72A FAM72B	3.49e-06	30	72	4	GO:0061099
GeneOntologyBiologicalProcess	negative regulation of signaling receptor activity	FAM72D FAM72C FAM72A FAM72B	5.17e-06	33	72	4	GO:2000272
GeneOntologyBiologicalProcess	protein modification by small protein conjugation or removal	RNF130 BIRC8 TRIM69 TRIM51 TRIM42 RNF20 NFX1 BIRC3 RFFL MINAR1 N4BP1 DTX3L MDM4 RNF128	8.63e-06	1009	72	14	GO:0070647
GeneOntologyBiologicalProcess	post-translational protein modification	RNF130 BIRC8 TRIM69 TRIM51 TRIM42 RNF20 NFX1 BIRC3 RFFL MINAR1 N4BP1 DTX3L MDM4 RNF128	1.74e-05	1074	72	14	GO:0043687
GeneOntologyBiologicalProcess	negative regulation of molecular function	ZNF675 FAM72D BIRC8 NWD1 FAM72C ABCE1 FAM72A WFDC6 PALM RFFL WFDC8 DTX3L FAM72B	3.94e-05	1005	72	13	GO:0044092
GeneOntologyBiologicalProcess	negative regulation of peptidyl-tyrosine phosphorylation	FAM72D FAM72C FAM72A FAM72B	5.37e-05	59	72	4	GO:0050732
GeneOntologyBiologicalProcess	sequestering of TGFbeta in extracellular matrix	FBN1 FBN2	7.18e-05	4	72	2	GO:0035583
GeneOntologyBiologicalProcess	negative regulation of protein metabolic process	ZNF675 FAM72D BIRC8 FAM72C FAM72A WFDC6 RFFL MINAR1 N4BP1 WFDC8 DTX3L MDM4 FAM72B	8.86e-05	1088	72	13	GO:0051248
GeneOntologyBiologicalProcess	regulation of protein tyrosine kinase activity	FAM72D FAM72C FAM72A FAM72B	9.94e-05	69	72	4	GO:0061097
GeneOntologyBiologicalProcess	maintenance of protein location in extracellular region	FBN1 FBN2	3.32e-04	8	72	2	GO:0071694
GeneOntologyBiologicalProcess	negative regulation of transferase activity	ZNF675 FAM72D FAM72C FAM72A DTX3L FAM72B	3.83e-04	273	72	6	GO:0051348
GeneOntologyBiologicalProcess	negative regulation of protein modification process	ZNF675 FAM72D FAM72C FAM72A MINAR1 N4BP1 DTX3L FAM72B	4.06e-04	512	72	8	GO:0031400
GeneOntologyBiologicalProcess	aminophospholipid transport	ATP11B ATP11A	4.26e-04	9	72	2	GO:0015917
GeneOntologyBiologicalProcess	sequestering of extracellular ligand from receptor	FBN1 FBN2	6.48e-04	11	72	2	GO:0035581
HumanPheno	Abnormal upper to lower segment ratio	FBN1 FBN2	2.42e-05	3	15	2	HP:0012772
MousePheno	increased germinal center B cell number	FAM72D FAM72C FAM72A N4BP1 FAM72B	1.12e-07	31	54	5	MP:0008177
MousePheno	abnormal somatic hypermutation frequency	FAM72D FAM72C FAM72A FAM72B	7.38e-07	19	54	4	MP:0004815
MousePheno	abnormal B cell apoptosis	FAM72D FAM72C FAM72A BIRC3 FAM72B	9.65e-07	47	54	5	MP:0008781
MousePheno	abnormal germinal center B cell number	FAM72D FAM72C FAM72A N4BP1 FAM72B	2.14e-06	55	54	5	MP:0013680
MousePheno	abnormal germinal center B cell morphology	FAM72D FAM72C FAM72A N4BP1 FAM72B	2.14e-06	55	54	5	MP:0008176
MousePheno	increased mature B cell number	FAM72D FBN1 FAM72C FAM72A BIRC3 N4BP1 FAM72B	3.52e-06	168	54	7	MP:0008210
MousePheno	increased B cell apoptosis	FAM72D FAM72C FAM72A FAM72B	3.80e-06	28	54	4	MP:0008782
MousePheno	increased B cell number	FAM72D FBN1 FAM72C FAM72A BIRC3 N4BP1 FAM72B	7.74e-05	271	54	7	MP:0005014
MousePheno	abnormal mature B cell number	FAM72D FBN1 FAM72C FAM72A BIRC3 N4BP1 FAM72B	1.86e-04	312	54	7	MP:0013701
MousePheno	abnormal class switch recombination	FAM72D FAM72C FAM72A FAM72B	2.65e-04	81	54	4	MP:0004816
MousePheno	abnormal mature B cell morphology	FAM72D FAM72C FAM72A BIRC3 N4BP1 FAM72B	3.41e-04	244	54	6	MP:0008171
Domain	ZF_RING_1	RNF214 RNF130 BIRC8 TRIM69 TRIM51 TRIM42 RNF20 NFX1 BIRC3 RFFL DTX3L MDM4 RNF128	1.84e-10	291	77	13	PS00518
Domain	ZF_RING_2	RNF214 RNF130 BIRC8 TRIM69 TRIM51 TRIM42 RNF20 NFX1 BIRC3 RFFL DTX3L MDM4 RNF128	2.47e-10	298	77	13	PS50089
Domain	FAM72	FAM72D FAM72C FAM72A FAM72B	2.67e-10	4	77	4	PF14976
Domain	FAM72	FAM72D FAM72C FAM72A FAM72B	2.67e-10	4	77	4	IPR026768
Domain	RING	RNF214 RNF130 BIRC8 TRIM69 TRIM51 TRIM42 RNF20 NFX1 BIRC3 RFFL DTX3L MDM4 RNF128	3.28e-10	305	77	13	SM00184
Domain	Znf_RING	RNF214 RNF130 BIRC8 TRIM69 TRIM51 TRIM42 RNF20 NFX1 BIRC3 RFFL DTX3L MDM4 RNF128	7.41e-10	326	77	13	IPR001841
Domain	Znf_RING/FYVE/PHD	RNF214 RNF130 BIRC8 TRIM69 TRIM51 TRIM42 RNF20 BIRC3 RFFL DTX3L MDM4 RNF128 RUFY4	4.42e-08	459	77	13	IPR013083
Domain	LRRC37AB_C	LRRC37A LRRC37A2 LRRC37B	2.69e-07	4	77	3	PF14914
Domain	LRRC37_N	LRRC37A LRRC37A2 LRRC37B	2.69e-07	4	77	3	IPR032754
Domain	LRRC37AB_C	LRRC37A LRRC37A2 LRRC37B	2.69e-07	4	77	3	IPR029423
Domain	LRRC37	LRRC37A LRRC37A2 LRRC37B	2.69e-07	4	77	3	PF15779
Domain	LRRC37A/B-like	LRRC37A LRRC37A2 LRRC37B	2.69e-07	4	77	3	IPR015753
Domain	zf-C3HC4	RNF130 BIRC8 TRIM69 TRIM51 TRIM42 RNF20 NFX1 DTX3L RNF128	3.35e-07	223	77	9	PF00097
Domain	TB	FBN1 FBN2 FST	5.56e-06	9	77	3	PS51364
Domain	TB_dom	FBN1 FBN2 FST	5.56e-06	9	77	3	IPR017878
Domain	-	RNF214 RNF130 TRIM69 TRIM51 RNF20 RFFL DTX3L MDM4 RNF128 RUFY4	1.52e-05	449	77	10	3.30.40.10
Domain	Fer4	DPYD ABCE1	5.02e-05	3	77	2	PF00037
Domain	FBN	FBN1 FBN2	5.02e-05	3	77	2	IPR011398
Domain	EGF-like_dom	PCSK5 EYS FBN1 FBN2 ADAM21 ADAM12 LRP1B	7.48e-05	249	77	7	IPR000742
Domain	ALBUMIN	GC ALB	1.00e-04	4	77	2	SM00103
Domain	Serum_albumin_N	GC ALB	1.00e-04	4	77	2	IPR014760
Domain	4Fe4S_Fe_S_CS	DPYD ABCE1	1.00e-04	4	77	2	IPR017900
Domain	ALBUMIN_1	GC ALB	1.00e-04	4	77	2	PS00212
Domain	Serum_albumin_CS	GC ALB	1.00e-04	4	77	2	IPR020857
Domain	Serum_albumin	GC ALB	1.00e-04	4	77	2	PF00273
Domain	ALBUMIN_2	GC ALB	1.00e-04	4	77	2	PS51438
Domain	4FE4S_FER_1	DPYD ABCE1	1.00e-04	4	77	2	PS00198
Domain	cEGF	FBN1 FBN2 LRP1B	1.64e-04	26	77	3	IPR026823
Domain	cEGF	FBN1 FBN2 LRP1B	1.64e-04	26	77	3	PF12662
Domain	4FE4S_FER_2	DPYD ABCE1	1.66e-04	5	77	2	PS51379
Domain	Serum_albumin-like	GC ALB	1.66e-04	5	77	2	IPR020858
Domain	4Fe4S_Fe-S-bd	DPYD ABCE1	1.66e-04	5	77	2	IPR017896
Domain	ALB/AFP/VDB	GC ALB	2.49e-04	6	77	2	IPR000264
Domain	TB	FBN1 FBN2	3.48e-04	7	77	2	PF00683
Domain	EGF_3	EYS FBN1 FBN2 ADAM21 ADAM12 LRP1B	4.19e-04	235	77	6	PS50026
Domain	BIR	BIRC8 BIRC3	4.62e-04	8	77	2	SM00238
Domain	-	BIRC8 BIRC3	4.62e-04	8	77	2	1.10.1170.10
Domain	BIR	BIRC8 BIRC3	4.62e-04	8	77	2	PF00653
Domain	BIR_REPEAT_2	BIRC8 BIRC3	4.62e-04	8	77	2	PS50143
Domain	-	FBN1 FBN2	4.62e-04	8	77	2	3.90.290.10
Domain	BIR_rpt	BIRC8 BIRC3	4.62e-04	8	77	2	IPR001370
Domain	BIR_REPEAT_1	BIRC8 BIRC3	4.62e-04	8	77	2	PS01282
Domain	Growth_fac_rcpt_	PCSK5 EYS FBN1 FBN2 LRP1B	4.64e-04	156	77	5	IPR009030
Domain	Znf_RING_CS	TRIM69 TRIM51 TRIM42 RNF20 DTX3L	5.67e-04	163	77	5	IPR017907
Domain	EGF_1	EYS FBN1 FBN2 ADAM21 ADAM12 LRP1B	6.44e-04	255	77	6	PS00022
Domain	EGF_Ca-bd_CS	EYS FBN1 FBN2 LRP1B	6.92e-04	97	77	4	IPR018097
Domain	EGF-like_CS	EYS FBN1 FBN2 ADAM21 ADAM12 LRP1B	7.27e-04	261	77	6	IPR013032
Domain	EGF_CA	EYS FBN1 FBN2 LRP1B	7.47e-04	99	77	4	PS01187
Domain	ASX_HYDROXYL	EYS FBN1 FBN2 LRP1B	7.76e-04	100	77	4	PS00010
Domain	EGF_2	EYS FBN1 FBN2 ADAM21 ADAM12 LRP1B	7.87e-04	265	77	6	PS01186
Domain	EGF-type_Asp/Asn_hydroxyl_site	EYS FBN1 FBN2 LRP1B	9.65e-04	106	77	4	IPR000152
Domain	P_typ_ATPase_c	ATP11B ATP11A	1.48e-03	14	77	2	IPR032630
Domain	P-type_ATPase_N	ATP11B ATP11A	1.48e-03	14	77	2	IPR032631
Domain	P-type_ATPase_IV	ATP11B ATP11A	1.48e-03	14	77	2	IPR006539
Domain	PhoLip_ATPase_C	ATP11B ATP11A	1.48e-03	14	77	2	PF16212
Domain	PhoLip_ATPase_N	ATP11B ATP11A	1.48e-03	14	77	2	PF16209
Domain	EGF_CA	EYS FBN1 FBN2 LRP1B	1.62e-03	122	77	4	SM00179
Domain	EGF-like_Ca-bd_dom	EYS FBN1 FBN2 LRP1B	1.72e-03	124	77	4	IPR001881
Domain	WAP	WFDC6 WFDC8	1.94e-03	16	77	2	SM00217
Domain	Disintegrin_CS	ADAM21 ADAM12	1.94e-03	16	77	2	IPR018358
Domain	WAP	WFDC6 WFDC8	1.94e-03	16	77	2	PF00095
Domain	WAP	WFDC6 WFDC8	2.19e-03	17	77	2	PS51390
Domain	-	WFDC6 WFDC8	2.19e-03	17	77	2	4.10.75.10
Domain	ADAM_CR	ADAM21 ADAM12	2.46e-03	18	77	2	PF08516
Domain	-	WFDC6 WFDC8	2.46e-03	18	77	2	4.10.410.10
Domain	KU	WFDC6 WFDC8	2.46e-03	18	77	2	SM00131
Domain	BPTI_KUNITZ_2	WFDC6 WFDC8	2.74e-03	19	77	2	PS50279
Domain	PA	RNF130 RNF128	2.74e-03	19	77	2	PF02225
Domain	PA_domain	RNF130 RNF128	2.74e-03	19	77	2	IPR003137
Domain	Kunitz_BPTI	WFDC6 WFDC8	2.74e-03	19	77	2	PF00014
Domain	BPTI_KUNITZ_1	WFDC6 WFDC8	2.74e-03	19	77	2	PS00280
Domain	EGF	PCSK5 EYS FBN1 FBN2 LRP1B	2.86e-03	235	77	5	SM00181
Domain	-	ADAM21 ADAM12	3.04e-03	20	77	2	4.10.70.10
Domain	Disintegrin	ADAM21 ADAM12	3.35e-03	21	77	2	PF00200
Domain	DISIN	ADAM21 ADAM12	3.35e-03	21	77	2	SM00050
Domain	WAP_dom	WFDC6 WFDC8	3.67e-03	22	77	2	IPR008197
Domain	Kunitz_BPTI	WFDC6 WFDC8	4.01e-03	23	77	2	IPR002223
Pubmed	Fam72a enforces error-prone DNA repair during antibody diversification.	FAM72D FAM72C FAM72A FAM72B	2.47e-11	4	79	4	34819671
Pubmed	Identification and characterisation of the novel amyloid-beta peptide-induced protein p17.	FAM72D FAM72C FAM72A FAM72B	1.23e-10	5	79	4	19755123
Pubmed	All-or-(N)One - an epistemological characterization of the human tumorigenic neuronal paralogous FAM72 gene loci.	FAM72D FAM72C FAM72A FAM72B	1.23e-10	5	79	4	26206078
Pubmed	FAM72A antagonizes UNG2 to promote mutagenic repair during antibody maturation.	FAM72D FAM72C FAM72A FAM72B	3.68e-10	6	79	4	34819670
Pubmed	cDNA sequence of a growth factor-inducible immediate early gene and characterization of its encoded protein.	FAM72D FAM72C FAM72A FAM72B	3.30e-08	15	79	4	1741163
Pubmed	Evolutionary dynamism of the primate LRRC37 gene family.	LRRC37A LRRC37A2 LRRC37B	1.34e-06	10	79	3	23064749
Pubmed	Homo- and heterotypic fibrillin-1 and -2 interactions constitute the basis for the assembly of microfibrils.	FBN1 FBN2	5.09e-06	2	79	2	12399449
Pubmed	Fibrillin-1 and fibrillin-2 are essential for formation of thick oxytalan fibers in human nonpigmented ciliary epithelial cells in vitro.	FBN1 FBN2	5.09e-06	2	79	2	21851253
Pubmed	Fibrillins can co-assemble in fibrils, but fibrillin fibril composition displays cell-specific differences.	FBN1 FBN2	5.09e-06	2	79	2	12429739
Pubmed	New Evidence Supporting the Role of FBN1 in the Development of Adolescent Idiopathic Scoliosis.	FBN1 FBN2	5.09e-06	2	79	2	30044367
Pubmed	Material and mechanical properties of bones deficient for fibrillin-1 or fibrillin-2 microfibrils.	FBN1 FBN2	5.09e-06	2	79	2	21440062
Pubmed	MAGP-2 has multiple binding regions on fibrillins and has covalent periodic association with fibrillin-containing microfibrils.	FBN1 FBN2	5.09e-06	2	79	2	15131124
Pubmed	Fibrillin-1 and fibrillin-2 in human embryonic and early fetal development.	FBN1 FBN2	5.09e-06	2	79	2	12524050
Pubmed	Microfibril structure masks fibrillin-2 in postnatal tissues.	FBN1 FBN2	5.09e-06	2	79	2	20404337
Pubmed	Fibrillln mutations in Marfan syndrome and related phenotypes.	FBN1 FBN2	5.09e-06	2	79	2	8791520
Pubmed	Structure and expression of fibrillin-2, a novel microfibrillar component preferentially located in elastic matrices.	FBN1 FBN2	5.09e-06	2	79	2	8120105
Pubmed	The fibrillinopathies: New insights with focus on the paradigm of opposing phenotypes for both FBN1 and FBN2.	FBN1 FBN2	5.09e-06	2	79	2	35419902
Pubmed	Fibrillin genes map to regions of conserved mouse/human synteny on mouse chromosomes 2 and 18.	FBN1 FBN2	5.09e-06	2	79	2	8307578
Pubmed	Reanalysis of ATP11B, a type IV P-type ATPase.	ATP11B ATP11A	5.09e-06	2	79	2	11790799
Pubmed	Fibrillin assembly: dimer formation mediated by amino-terminal sequences.	FBN1 FBN2	5.09e-06	2	79	2	10504303
Pubmed	Developmental expression of fibrillin genes suggests heterogeneity of extracellular microfibrils.	FBN1 FBN2	5.09e-06	2	79	2	7744963
Pubmed	Fibrillin microfibrils in bone physiology.	FBN1 FBN2	5.09e-06	2	79	2	26408953
Pubmed	Arg-Gly-Asp-containing domains of fibrillins-1 and -2 distinctly regulate lung fibroblast migration.	FBN1 FBN2	5.09e-06	2	79	2	18006876
Pubmed	Rare variants in FBN1 and FBN2 are associated with severe adolescent idiopathic scoliosis.	FBN1 FBN2	5.09e-06	2	79	2	24833718
Pubmed	Nonselective assembly of fibrillin 1 and fibrillin 2 in the rodent ocular zonule and in cultured cells: implications for Marfan syndrome.	FBN1 FBN2	5.09e-06	2	79	2	24265020
Pubmed	In vivo studies of mutant fibrillin-1 microfibrils.	FBN1 FBN2	5.09e-06	2	79	2	20529844
Pubmed	Immunohistochemical expression of fibrillin-1 and fibrillin-2 during tooth development.	FBN1 FBN2	5.09e-06	2	79	2	25524144
Pubmed	Fibrillin-1 mutations causing Weill-Marchesani syndrome and acromicric and geleophysic dysplasias disrupt heparan sulfate interactions.	FBN1 FBN2	5.09e-06	2	79	2	23133647
Pubmed	Fibrillins 1 and 2 perform partially overlapping functions during aortic development.	FBN1 FBN2	5.09e-06	2	79	2	16407178
Pubmed	Linkage of Marfan syndrome and a phenotypically related disorder to two different fibrillin genes.	FBN1 FBN2	5.09e-06	2	79	2	1852206
Pubmed	N-terminal domains of fibrillin 1 and fibrillin 2 direct the formation of homodimers: a possible first step in microfibril assembly.	FBN1 FBN2	5.09e-06	2	79	2	10359653
Pubmed	Differential expression of BIRC family genes in chronic myeloid leukaemia--BIRC3 and BIRC8 as potential new candidates to identify disease progression.	BIRC8 BIRC3	5.09e-06	2	79	2	24266799
Pubmed	A comprehensive framework of E2-RING E3 interactions of the human ubiquitin-proteasome system.	RNF130 BIRC8 NFX1 BIRC3 RFFL	7.61e-06	118	79	5	19690564
Pubmed	Interaction of tropoelastin with the amino-terminal domains of fibrillin-1 and fibrillin-2 suggests a role for the fibrillins in elastic fiber assembly.	FBN1 FBN2	1.53e-05	3	79	2	10825173
Pubmed	Adamts10 inactivation in mice leads to persistence of ocular microfibrils subsequent to reduced fibrillin-2 cleavage.	FBN1 FBN2	1.53e-05	3	79	2	30201140
Pubmed	Inhibitor of apoptosis proteins are required for effective fusion of autophagosomes with lysosomes.	BIRC8 BIRC3	1.53e-05	3	79	2	29743550
Pubmed	Human serum albumin and p53-activating peptide fusion protein is able to promote apoptosis and deliver fatty acid-modified molecules.	ALB MDM4	1.53e-05	3	79	2	24278348
Pubmed	Follistatin mediates learning and synaptic plasticity via regulation of Asic4 expression in the hippocampus.	GAD2 FST	1.53e-05	3	79	2	34544873
Pubmed	Linkage between vitamin D-binding protein and alpha-fetoprotein in the mouse.	GC ALB	1.53e-05	3	79	2	8835525
Pubmed	Fibrillin-1 and -2 differentially modulate endogenous TGF-β and BMP bioavailability during bone formation.	FBN1 FBN2	1.53e-05	3	79	2	20855508
Pubmed	Latent transforming growth factor beta-binding protein 1 interacts with fibrillin and is a microfibril-associated protein.	FBN1 FBN2	3.05e-05	4	79	2	12429738
Pubmed	Human eye development is characterized by coordinated expression of fibrillin isoforms.	FBN1 FBN2	3.05e-05	4	79	2	25406291
Pubmed	Extracellular microfibrils control osteoblast-supported osteoclastogenesis by restricting TGF{beta} stimulation of RANKL production.	FBN1 FBN2	3.05e-05	4	79	2	20729550
Pubmed	Heparin/heparan sulfate controls fibrillin-1, -2 and -3 self-interactions in microfibril assembly.	FBN1 FBN2	3.05e-05	4	79	2	25034023
Pubmed	Posttranscriptional downregulation of c-IAP2 by the ubiquitin protein ligase c-IAP1 in vivo.	BIRC8 BIRC3	3.05e-05	4	79	2	15798218
Pubmed	X-Linked inhibitor of apoptosis protein is involved in mutant SOD1-mediated neuronal degeneration.	BIRC8 BIRC3	3.05e-05	4	79	2	12153481
Pubmed	Comprehensive genetic analysis of relevant four genes in 49 patients with Marfan syndrome or Marfan-related phenotypes.	FBN1 FBN2	3.05e-05	4	79	2	16835936
Pubmed	Inhibitor of Apoptosis Proteins (IAPs) Limit RIPK1-Mediated Skin Inflammation.	BIRC8 BIRC3	3.05e-05	4	79	2	28647349
Pubmed	Primate segmental duplication creates novel promoters for the LRRC37 gene family within the 17q21.31 inversion polymorphism region.	LRRC37A LRRC37A2	3.05e-05	4	79	2	22419166
Pubmed	The N-terminal extension of UBE2E ubiquitin-conjugating enzymes limits chain assembly.	BIRC3 RFFL	3.05e-05	4	79	2	23871895
Pubmed	Apoptotic sensitivity of murine IAP-deficient cells.	BIRC8 BIRC3	3.05e-05	4	79	2	18684108
Pubmed	FLRG, a new ADAM12-associated protein, modulates osteoclast differentiation.	FST ADAM12	3.05e-05	4	79	2	15574124
Pubmed	Characterization of Microfibrillar-associated Protein 4 (MFAP4) as a Tropoelastin- and Fibrillin-binding Protein Involved in Elastic Fiber Formation.	FBN1 FBN2	5.07e-05	5	79	2	26601954
Pubmed	ARTS binds to a distinct domain in XIAP-BIR3 and promotes apoptosis by a mechanism that is different from other IAP-antagonists.	BIRC8 BIRC3	5.07e-05	5	79	2	21695558
Pubmed	Relaxin regulates fibrillin 2, but not fibrillin 1, mRNA and protein expression by human dermal fibroblasts and murine fetal skin.	FBN1 FBN2	5.07e-05	5	79	2	12590922
Pubmed	Identification of DIABLO, a mammalian protein that promotes apoptosis by binding to and antagonizing IAP proteins.	BIRC8 BIRC3	5.07e-05	5	79	2	10929712
Pubmed	IAP antagonists sensitize murine osteosarcoma cells to killing by TNFα.	BIRC8 BIRC3	5.07e-05	5	79	2	27129149
Pubmed	Fibrillin-1 interactions with fibulins depend on the first hybrid domain and provide an adaptor function to tropoelastin.	FBN1 FBN2	5.07e-05	5	79	2	17255108
Pubmed	POGLUT2 and POGLUT3 O-glucosylate multiple EGF repeats in fibrillin-1, -2, and LTBP1 and promote secretion of fibrillin-1.	FBN1 FBN2	5.07e-05	5	79	2	34411563
Pubmed	ATPase reaction cycle of P4-ATPases affects their transport from the endoplasmic reticulum.	ATP11B ATP11A	5.07e-05	5	79	2	31571211
Pubmed	Cloning and expression of apoptosis inhibitory protein homologs that function to inhibit apoptosis and/or bind tumor necrosis factor receptor-associated factors.	BIRC8 BIRC3	5.07e-05	5	79	2	8643514
Pubmed	Survivin acts as an antiapoptotic factor during the development of mouse preimplantation embryos.	BIRC8 BIRC3	5.07e-05	5	79	2	12679106
Pubmed	Development, composition, and structural arrangements of the ciliary zonule of the mouse.	FBN1 FBN2	5.07e-05	5	79	2	23493297
Pubmed	The E3 ubiquitin ligase GREUL1 anteriorizes ectoderm during Xenopus development.	RNF130 RNF128	7.60e-05	6	79	2	12435366
Pubmed	cIAP1 and cIAP2 limit macrophage necroptosis by inhibiting Rip1 and Rip3 activation.	BIRC8 BIRC3	7.60e-05	6	79	2	22576661
Pubmed	Of mice and Marfan: genetic linkage analyses of the fibrillin genes, Fbn1 and Fbn2, in the mouse genome.	FBN1 FBN2	7.60e-05	6	79	2	7873879
Pubmed	HtrA2 promotes cell death through its serine protease activity and its ability to antagonize inhibitor of apoptosis proteins.	BIRC8 BIRC3	7.60e-05	6	79	2	11604410
Pubmed	The inhibitors of apoptosis (IAPs) and their emerging role in cancer.	BIRC8 BIRC3	1.06e-04	7	79	2	9916987
Pubmed	Regulation of limb patterning by extracellular microfibrils.	FBN1 FBN2	1.06e-04	7	79	2	11470817
Pubmed	The inhibitors of apoptosis: there is more to life than Bcl2.	BIRC8 BIRC3	1.06e-04	7	79	2	14634619
Pubmed	An Interaction Landscape of Ubiquitin Signaling.	TTF2 SETDB1 BIRC8 ZNF330 NFX1 BIRC3 N4BP1	1.14e-04	481	79	7	28190767
Pubmed	IAPs limit activation of RIP kinases by TNF receptor 1 during development.	BIRC8 BIRC3	1.41e-04	8	79	2	22327219
Pubmed	Putative functions of extracellular matrix glycoproteins in secondary palate morphogenesis.	FBN1 FBN2	1.41e-04	8	79	2	23055981
Pubmed	Adamts17 is involved in skeletogenesis through modulation of BMP-Smad1/5/8 pathway.	FBN1 FBN2	1.41e-04	8	79	2	31201465
Pubmed	Critical function of endogenous XIAP in regulating caspase activation during sympathetic neuronal apoptosis.	BIRC8 BIRC3	1.41e-04	8	79	2	14623868
Pubmed	Receptor Elimination by E3 Ubiquitin Ligase Recruitment (REULR): A Targeted Protein Degradation Toolbox.	RNF130 RNF128	1.41e-04	8	79	2	37011906
Pubmed	Regulation of apoptosis by XIAP ubiquitin-ligase activity.	BIRC8 BIRC3	1.41e-04	8	79	2	18708583
Pubmed	Targeting of bone morphogenetic protein growth factor complexes to fibrillin.	FBN1 FBN2	1.41e-04	8	79	2	18339631
Pubmed	Microfibril-associated glycoprotein-2 interacts with fibrillin-1 and fibrillin-2 suggesting a role for MAGP-2 in elastic fiber assembly.	FBN1 FBN2	1.82e-04	9	79	2	12122015
Pubmed	BIRC7-E2 ubiquitin conjugate structure reveals the mechanism of ubiquitin transfer by a RING dimer.	BIRC3 MDM4	1.82e-04	9	79	2	22902369
Pubmed	Poglut2/3 double knockout in mice results in neonatal lethality with reduced levels of fibrillin in lung tissues.	FBN1 FBN2	1.82e-04	9	79	2	38844137
Pubmed	Limb- and tendon-specific Adamtsl2 deletion identifies a role for ADAMTSL2 in tendon growth in a mouse model for geleophysic dysplasia.	FBN1 FBN2	2.27e-04	10	79	2	30738849
Pubmed	Caspase 9 is constitutively activated in mouse oocytes and plays a key role in oocyte elimination during meiotic prophase progression.	BIRC8 BIRC3	2.27e-04	10	79	2	23384561
Pubmed	Reproduction and immunity-driven natural selection in the human WFDC locus.	WFDC6 WFDC8	2.27e-04	10	79	2	23292442
Pubmed	Omi/HtrA2 catalytic cleavage of inhibitor of apoptosis (IAP) irreversibly inactivates IAPs and facilitates caspase activity in apoptosis.	BIRC8 BIRC3	2.27e-04	10	79	2	12815069
Pubmed	Ring finger protein20 regulates hepatic lipid metabolism through protein kinase A-dependent sterol regulatory element binding protein1c degradation.	RNF130 RNF20	2.27e-04	10	79	2	24425205
Pubmed	Suppression of caspase-8- and -10-associated RING proteins results in sensitization to death ligands and inhibition of tumor cell growth.	BIRC3 RFFL	3.31e-04	12	79	2	15069192
Pubmed	A distinct transcriptome characterizes neural crest-derived cells at the migratory wavefront during enteric nervous system development.	FBN1 FBN2	3.31e-04	12	79	2	36779913
Pubmed	The ubiquitin ligase XIAP recruits LUBAC for NOD2 signaling in inflammation and innate immunity.	BIRC8 BIRC3	3.31e-04	12	79	2	22607974
Pubmed	Disruption of murine Adamtsl4 results in zonular fiber detachment from the lens and in retinal pigment epithelium dedifferentiation.	FBN1 FBN2	3.31e-04	12	79	2	26405179
Pubmed	ATP9B, a P4-ATPase (a putative aminophospholipid translocase), localizes to the trans-Golgi network in a CDC50 protein-independent manner.	ATP11B ATP11A	3.31e-04	12	79	2	21914794
Pubmed	Cellular inhibitor of apoptosis proteins prevent clearance of hepatitis B virus.	BIRC8 BIRC3	3.31e-04	12	79	2	25902529
Pubmed	Differential expression of putative transbilayer amphipath transporters.	ATP11B ATP11A	3.91e-04	13	79	2	11015572
Pubmed	Interplay between Caspase 9 and X-linked Inhibitor of Apoptosis Protein (XIAP) in the oocyte elimination during fetal mouse development.	BIRC8 BIRC3	3.91e-04	13	79	2	31624230
Pubmed	XIAP Loss Triggers RIPK3- and Caspase-8-Driven IL-1β Activation and Cell Death as a Consequence of TLR-MyD88-Induced cIAP1-TRAF2 Degradation.	BIRC8 BIRC3	4.55e-04	14	79	2	28723569
Pubmed	A locus on human chromosome 20 contains several genes expressing protease inhibitor domains with homology to whey acidic protein.	WFDC6 WFDC8	4.55e-04	14	79	2	12206714
Pubmed	Parathyroid hormone regulates fetal-placental mineral homeostasis.	GC ALB	5.25e-04	15	79	2	19968565
Pubmed	Common body mass index-associated variants confer risk of extreme obesity.	FBN2 ANO3	5.25e-04	15	79	2	19553259
Pubmed	Dual role of Fam208a during zygotic cleavage and early embryonic development.	SETDB1 ALB	5.99e-04	16	79	2	34216590
Pubmed	The evolution of a genetic locus encoding small serine proteinase inhibitors.	WFDC6 WFDC8	5.99e-04	16	79	2	15950183
Interaction	UBE2D3 interactions	RNF130 BIRC8 TRIM69 BIRC3 RFFL DTX3L MDM4 RNF128	1.25e-05	283	77	8	int:UBE2D3
Interaction	UBE2D1 interactions	RNF130 BIRC8 TRIM69 BIRC3 RFFL DTX3L MDM4 RNF128	1.64e-05	294	77	8	int:UBE2D1
Cytoband	15q21.1	SLC24A5 TRIM69 FBN1	3.65e-05	37	79	3	15q21.1
Cytoband	Ensembl 112 genes in cytogenetic band chr11p12	TTC17 LRRC4C	4.91e-04	19	79	2	chr11p12
Cytoband	1p22	TTF2 DPYD	5.44e-04	20	79	2	1p22
Cytoband	11q11	TRIM51 OR4C11	3.01e-03	47	79	2	11q11
Cytoband	Ensembl 112 genes in cytogenetic band chr15q21	SLC24A5 TRIM69 FBN1	3.59e-03	177	79	3	chr15q21
Cytoband	13q34	ATP11A CHAMP1	3.95e-03	54	79	2	13q34
Cytoband	20q13.12	WFDC6 WFDC8	4.85e-03	60	79	2	20q13.12
GeneFamily	Ring finger proteins	RNF214 RNF130 TRIM69 TRIM51 TRIM42 RNF20 BIRC3 RFFL DTX3L RNF128	2.21e-09	275	48	10	58
GeneFamily	Ring finger proteins\|Baculoviral IAP repeat containing\|Caspase recruitment domain containing	BIRC8 BIRC3	1.91e-04	8	48	2	419
GeneFamily	Zinc fingers C2H2-type\|ZF class homeoboxes and pseudogenes	ZNF675 SP2 ZNF43 ZNF330 ZFP64 ZNF483 ZNF782 CHAMP1	5.49e-04	718	48	8	28
GeneFamily	ATPase phospholipid transporting	ATP11B ATP11A	7.09e-04	15	48	2	1210
GeneFamily	WAP four-disulfide core domain containing\|Fibronectin type III domain containing	WFDC6 WFDC8	1.03e-03	18	48	2	361
GeneFamily	Ring finger proteins\|Tripartite motif containing\|ARF GTPase family	TRIM69 TRIM51 TRIM42	2.05e-03	95	48	3	59
GeneFamily	ADAM metallopeptidase domain containing\|CD molecules	ADAM21 ADAM12	2.32e-03	27	48	2	47
ToppCell	Neuronal-Inhibitory-iB-iB_4(SST)-ADGRG6-\|Neuronal / cells hierarchy compared to all cells using T-Statistic	PCSK5 GAD2 EYS FBN2 KCP DKK2	1.52e-06	200	79	6	a9cdddc4e985dae59521e557479c24fcc2ac727d
ToppCell	Neuronal-Inhibitory-iB-iB_4(SST)-ADGRG6--L3-5\|Neuronal / cells hierarchy compared to all cells using T-Statistic	PCSK5 GAD2 EYS FBN2 KCP DKK2	1.52e-06	200	79	6	33b9199e0dfc267e2cea20b82d1c167f8adcc635
ToppCell	Neuronal-Inhibitory-iB-iB_4(SST)-ADGRG6\|Neuronal / cells hierarchy compared to all cells using T-Statistic	PCSK5 GAD2 EYS FBN2 KCP DKK2	1.52e-06	200	79	6	9719fabddc34051949468a7520289e3c750de4f8
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-Adaptive_/_Maladaptive_/_Repairing_Fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	TTYH2 LRRC4C FST SLC16A8 GFRA3	1.46e-05	174	79	5	9c916af5eebd932f67dc9117e1d26ff194a2ff2c
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	TTYH2 LRRC4C FST SLC16A8 GFRA3	1.46e-05	174	79	5	bc71521f44a5fe013af42b06b5d1bd2446ecf3b5
ToppCell	droplet-Lung-nan-3m-Mesenchymal-pericyte_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TTYH2 KCP WFDC8 LRRC4C FST	1.59e-05	177	79	5	65709bd546cb1ec6aa2ddd8b2adb46e174eb9a9a
ToppCell	droplet-Lung-nan-3m-Mesenchymal-Pericyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TTYH2 KCP WFDC8 LRRC4C FST	1.59e-05	177	79	5	8684d47a547e2a06496f15e8da0200ecddc431e0
ToppCell	droplet-Bladder-BLADDER-1m-Epithelial-endothelial_cell\|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	OLFML2A FAM72A TTYH2 LRRC4C GFRA3	1.67e-05	179	79	5	c7c74e26bbf86c5326ee38bac7de111d5414f46b
ToppCell	wk_15-18-Epithelial-Proximal_epithelial-GHRL+_neuroendocrine\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	GAD2 STARD10 CXXC4 GC RNF128	1.86e-05	183	79	5	8820cfed27b292bc0bc9cde4005219ed41900552
ToppCell	wk_15-18-Epithelial-PNS-intermediate_Schwann\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	TNFRSF12A OLFML2A LRRC4C FST GFRA3	1.86e-05	183	79	5	d874aa9a856f79626c8a8371f6196a77b7d662ee
ToppCell	343B-Lymphocytic-CD4_T-cell-Proliferating_T_cell\|CD4_T-cell / Donor, Lineage, Cell class and subclass (all cells)	FAM72D FBN1 FAM72C DIPK1B FAM72B	1.86e-05	183	79	5	f03d87b556a3d50360d4eb6126b3466fe7266677
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-TAM-MG-TAM-MG_pro-infl_II-C\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	FAM72D ADAM21 FAM72A LINC01554 FAM72B	2.12e-05	188	79	5	fe8c3283f1da7f3ae8dabaa338efebf3947d8658
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	GAD2 FBN2 KCP MINAR1 DKK2	2.34e-05	192	79	5	dc40ef2341e5d6a6d479f140e023fe1bf687928d
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST-Inh_L3-5_SST_MAFB\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	PCSK5 GAD2 EYS FBN2 DKK2	2.40e-05	193	79	5	c7e9e6e4bf5e07c9cbdf1aa7c8828f4b2500e3ff
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST-Inh_L3-5_SST_MAFB\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	PCSK5 GAD2 EYS FBN2 KCP	2.46e-05	194	79	5	83863da11dfbe59b2d0a2c08db40b537c150588c
ToppCell	Parenchymal-10x3prime_v2-Immune_Myeloid-Macrophage_alveolar-Macro_alv_dividing\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	FBN2 MCM8 FAM72C FAM72A FAM72B	2.78e-05	199	79	5	c6d59ed26eadd3c41acfe1b4d929270e00ea3e95
ToppCell	10x5'v1-week_14-16-Mesenchymal_osteo-stroma-osteochondral_precursor\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	OLFML2A FBN1 SNX7 RNF128 ADAM12	2.85e-05	200	79	5	ad3fb8ef0be45032369d1325024787fbe1dfb8d6
ToppCell	Neuronal-Inhibitory-iB-iB_4(SST)\|Neuronal / cells hierarchy compared to all cells using T-Statistic	PCSK5 GAD2 FBN2 KCP DKK2	2.85e-05	200	79	5	347a510755374c6a66acee326565dfc447993f18
ToppCell	Severe-Myeloid-Mast-\|Severe / Condition, Lineage, Cell class and cell subclass	SLC24A5 ADAM12 LRP1B GFRA3	1.29e-04	145	79	4	ce307d45425a5191882078f049f85477eec40b69
ToppCell	Severe-Myeloid-Mast\|Severe / Condition, Lineage, Cell class and cell subclass	SLC24A5 ADAM12 LRP1B GFRA3	1.29e-04	145	79	4	e0bfd2ffdbd6c197ef0a04e983396ebd87ef7127
ToppCell	Smart-seq2-blood_(Smart-seq2)-myeloid-myeloid_granulocytic-neutrophil\|blood_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	TRIM51 LRRC4C ANO3 DKK2	1.43e-04	149	79	4	c5eedb54ef2e0f131aa6730612c921bc19479632
ToppCell	Smart-seq2-blood_(Smart-seq2)-myeloid-myeloid_granulocytic\|blood_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	TRIM51 LRRC4C ANO3 DKK2	1.43e-04	149	79	4	a22417286de8606f0cc94f86b70bce17aeefb9c2
ToppCell	droplet-Liver-nan\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DPYD STARD10 GC ALB	1.54e-04	152	79	4	1febeeb7376e34b9f86c81b2cb1314ee12408864
ToppCell	droplet-Liver-nan-3m\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DPYD STARD10 GC ALB	1.54e-04	152	79	4	faa92f7c5a6db9f1eb7d8ec930ba7c8ed9fd1bf1
ToppCell	TCGA-Kidney-Primary_Tumor-Renal_Cell_Carcinoma-Kidney_Clear_Cell_Renal_Carcinoma-6\|TCGA-Kidney / Sample_Type by Project: Shred V9	FAM72D FAM72C FAM72A FAM72B	1.71e-04	156	79	4	d249747c7108a0edfc72d24c09b0b0e4ed662b40
ToppCell	Control-Epithelial_airway\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	STARD10 ALB ANO3 GFRA3	1.79e-04	158	79	4	35aee1c3b92169e73569331022833cb44ab7e7e8
ToppCell	facs-Lung-EPCAM-3m-Endothelial-Capillary_Type_1_Cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HSD17B7 TTYH2 KCP GC	1.93e-04	161	79	4	a7e74bc80ac11250e353e5614b19c05793fc2e95
ToppCell	Mild-Myeloid-Mast\|Mild / Condition, Lineage, Cell class and cell subclass	EYS MINAR1 ADAM12 GFRA3	2.12e-04	165	79	4	5fa9552c37890c5cc7e672a47038aebba2413cb4
ToppCell	Mild-Myeloid-Mast-\|Mild / Condition, Lineage, Cell class and cell subclass	EYS MINAR1 ADAM12 GFRA3	2.12e-04	165	79	4	93d3909a0f5f43d473d5005c842d7d73e25eceed
ToppCell	facs-Limb_Muscle-forelimb_and_hindlimb-18m-Mesenchymal-mesenchymal_stem_cell\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FBN1 LRRC4C FST DKK2	2.12e-04	165	79	4	f80665b75d43f1bf6919d59fc762e7e0bac653f2
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST-Inh_L2-4_SST_AHR\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	GAD2 EYS KCP MINAR1	2.21e-04	167	79	4	904a42309ef3a3695bd74c3737c6bec25b742677
ToppCell	Control-Epithelial_airway-Club_cells-Airway\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	STARD10 ALB ANO3 GFRA3	2.27e-04	168	79	4	ce87981f4da2779de952c2e5d2bbcdabb265e705
ToppCell	Control-Epithelial_airway-Club_cells\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	STARD10 ALB ANO3 GFRA3	2.27e-04	168	79	4	e85bc5398eb36b2b0773a8a7082e3ba740452165
ToppCell	droplet-Heart-HEART_(LV+RV_ONLY)-30m-Hematologic-fibroblast\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DPYD FAM72A KCP RUFY4	2.32e-04	169	79	4	15a9183c838cc6384d7f5dfeae3d30602964c9b3
ToppCell	E18.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-PMP-PMP_prolif\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	TTF2 MCM8 KCP ADAM12	2.37e-04	170	79	4	b1a16600754e0c12f7d39c9221f1b03135833f16
ToppCell	343B-Lymphocytic-CD4_T-cell-Proliferating_T_cell\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	FAM72D FAM72C DIPK1B FAM72B	2.42e-04	171	79	4	4ccd88cf812dd8bfdc55159c6f504e9c84e4f4fc
ToppCell	facs-Lung-EPCAM-3m-Mesenchymal-pericyte_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MCM8 KCP WFDC8 LRRC4C	2.53e-04	173	79	4	3059325901b1e5e12a1a91183f14267288b2f600
ToppCell	facs-Lung-EPCAM-3m-Mesenchymal-Pericyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MCM8 KCP WFDC8 LRRC4C	2.53e-04	173	79	4	36c8338463ee4cc432f568728d55989360f9a68d
ToppCell	facs-Lung-EPCAM-18m-Mesenchymal-Pericyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TTYH2 WFDC8 LRRC4C FST	2.65e-04	175	79	4	d2ff8fedca9039cbd45cfd9dec88f4edbe7fe4fc
ToppCell	facs-Lung-EPCAM-18m-Mesenchymal-pericyte_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TTYH2 WFDC8 LRRC4C FST	2.65e-04	175	79	4	a7310950e8d51b3004ea3aee8ce9948fe8655112
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_E_(THEMIS)-Glut_D_(IT_RORB_THEMIS_LINC00507)_6\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	DPYD LRP1B ANO3 DKK2	2.70e-04	176	79	4	0710689e66deba179b0a8038cdd56b4834984f12
ToppCell	wk_20-22-Epithelial-PNS-Late_Schwann\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	OLFML2A FST ANO3 GFRA3	2.70e-04	176	79	4	81924471d8a8c5bd8eedf294c007e25b6cd3e417
ToppCell	facs-Lung-Endomucin-24m-Endothelial-endothelial_cell_of_lymphatic_vessel\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	OLFML2A NWD1 DIPK1B PALM	2.70e-04	176	79	4	057d2759fdc67176c25802b57a78064d8cc93205
ToppCell	facs-Lung-Endomucin-24m-Endothelial-Lymphatic_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	OLFML2A NWD1 DIPK1B PALM	2.70e-04	176	79	4	b81e5d23b31cefc8d374ef403e21acc390c14a80
ToppCell	5'-GW_trimst-1.5-SmallIntestine-Epithelial-neuro-epithelial-EC_cells_(TAC1+)\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	GAD2 STARD10 GC RNF128	2.70e-04	176	79	4	71f96cace3f20fbef975037f4deff9b82b0282a1
ToppCell	droplet-Lung-3m-Mesenchymal-myofibroblast-pericyte_cell-pericyte\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	TTYH2 WFDC8 LRRC4C FST	2.70e-04	176	79	4	e2b59a904c5c8f9c88e1e63788e9b6485f22edd0
ToppCell	356C-Myeloid-Dendritic-cDC_proliferating_2\|356C / Donor, Lineage, Cell class and subclass (all cells)	FAM72D DKK2 FAM72B RUFY4	2.70e-04	176	79	4	4bba41ebf9dd187c8705a6997ed039878de62b4e
ToppCell	droplet-Lung-3m-Mesenchymal-myofibroblast-pericyte_cell\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	TTYH2 WFDC8 LRRC4C FST	2.70e-04	176	79	4	f931192e3cc65414e2245354f443473696cc7ce8
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L1-2_PVALB_TAC1\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	EYS FBN2 KCP DKK2	2.82e-04	178	79	4	1985271984e6747941c8d2097d9c58f0260f021a
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_E_(THEMIS)-Glut_D_(IT_RORB_THEMIS_LINC00507)_6-Exc_L6_THEMIS_LINC00343\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	DPYD LRP1B ANO3 DKK2	2.82e-04	178	79	4	6f61490d79cd1727ed2d5cc673823dd4efdafac1
ToppCell	facs-Lung-18m-Mesenchymal-myofibroblast-pericyte_cell\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	TTYH2 WFDC8 LRRC4C FST	2.82e-04	178	79	4	8bae5db100f4563aa1fc7f881e7f8c59d669e37a
ToppCell	facs-Lung-18m-Mesenchymal-myofibroblast-pericyte_cell-pericyte\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	TTYH2 WFDC8 LRRC4C FST	2.82e-04	178	79	4	bc0336692b84bd0fa49747ed5a031b8ed8afa0fd
ToppCell	3'-GW_trimst-2-LargeIntestine-Epithelial-neuro-epithelial-EC_cells_(TAC1+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SLC24A5 GAD2 EYS STARD10	2.95e-04	180	79	4	d553aba594f5304f1c09ff9c6d49b64cd7ee7850
ToppCell	3'-GW_trimst-2-LargeIntestine-Neuronal-Glial_immature-Glia_1_(DHH+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	OLFML2A RNF130 TRIM51 GFRA3	2.95e-04	180	79	4	b294f9db1e2ff51c94cde64fae4c2b057c0030a1
ToppCell	facs-Lung-18m-Mesenchymal-myofibroblast\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	TTYH2 WFDC8 LRRC4C FST	3.01e-04	181	79	4	dff264815a3569f5666d0bbc3867c0496cd78774
ToppCell	metastatic_Brain-Fibroblasts-Myofibroblasts\|metastatic_Brain / Location, Cell class and cell subclass	FBN1 FBN2 FST DKK2	3.01e-04	181	79	4	bd0b5f74f9c81ec0f1592710774a4fdf33d9d5a9
ToppCell	PND14-Immune-Immune_Myeloid-Monocytic-Macrophage-AM-AM_G2M\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	TTF2 MCM8 TTYH2 RUFY4	3.07e-04	182	79	4	21dcab170ffeef89faa9fee5008568cb6e15c694
ToppCell	wk_08-11-Mesenchymal-Chondrocyte-ASPN+_chondrocyte\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	SERTAD4 FST ANO3 DKK2	3.07e-04	182	79	4	0e52ba34e179d9bfaac7b49920b44c710b2b8dad
ToppCell	3'-GW_trimst-1.5-LargeIntestine-Neuronal-Glial_immature\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	PCSK5 OLFML2A RNF130 GFRA3	3.07e-04	182	79	4	ecb5624c9074cc6449fad961df54c926c2681d54
ToppCell	moderate-Epithelial-IRC-IFNG_responsive_cell\|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	TNFRSF12A BIRC3 FST RUFY4	3.14e-04	183	79	4	4ba879552e2101a341f3224826d364ac64c72260
ToppCell	TCGA-Liver-Primary_Tumor-Hepatocellular_Carcinoma-Hepatocellular_Carcinoma-5\|TCGA-Liver / Sample_Type by Project: Shred V9	FAM72D FAM72C FAM72A FAM72B	3.14e-04	183	79	4	f604a8b62c7088fad8365dbf8d910fc980bd3ba8
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST-Inh_L5-6_SST_KLHL14\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	GAD2 FBN2 KCP DKK2	3.14e-04	183	79	4	439b1d1373b7cc73d65f3b59037a6def7cf8f4ba
ToppCell	droplet-Heart-HEART_(LV+RV_ONLY)-30m-Neuronal-cardiac_neuron\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MCM8 LRRC4C FST GFRA3	3.14e-04	183	79	4	8330c39184ce076e1f95fd3725b68af551d89db0
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FBN2 LRRC4C LRP1B ANO3	3.20e-04	184	79	4	2cbed6462fea2622871bb7e49b0df3d984239281
ToppCell	3'-GW_trimst-2-LargeIntestine-Neuronal-Glial_immature\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	OLFML2A RNF130 TRIM51 GFRA3	3.20e-04	184	79	4	226ccac00ac1c3a0ad7283785fd14312320e0ca6
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FBN2 LRRC4C LRP1B ANO3	3.20e-04	184	79	4	ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FBN2 LRRC4C LRP1B ANO3	3.20e-04	184	79	4	2b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell	droplet-Lung-21m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l17\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CXXC4 SERTAD4 DIPK1B FST	3.27e-04	185	79	4	1b990e3089772be2b38c6d7ea0d1bf22461ae3ea
ToppCell	droplet-Pancreas-Endocrine-21m-Epithelial-pancreatic_A_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RNF130 GC ANO3 GFRA3	3.27e-04	185	79	4	4e40d3103ebf4a7066b7ce300b6ef700ba0e2863
ToppCell	PND07-28-samps-Mesenchymal-Myofibroblast-myofibroblast_-_mature_-_C\|PND07-28-samps / Age Group, Lineage, Cell class and subclass	TNFRSF12A PCSK5 FBN1 FBN2	3.27e-04	185	79	4	427176ad9ab8d9511200fb0a132cfd1e835fe35c
ToppCell	3'-GW_trimst-2-SmallIntestine-Epithelial-neuro-epithelial-EC_cells_(TAC1+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	GAD2 STARD10 GC LRP1B	3.27e-04	185	79	4	eb78614c4acf8d2ce7874d7e51e16997b76127ef
ToppCell	droplet-Kidney-KIDNEY-1m-Mesenchymal-Stroma____fibroblast\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FBN1 FBN2 FST GFRA3	3.27e-04	185	79	4	785c55d39909fac74415f24427979691e7e694e6
ToppCell	droplet-Kidney-KIDNEY-1m-Mesenchymal\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FBN1 FBN2 FST GFRA3	3.27e-04	185	79	4	97a1dcacbc48dc3f41c26fbb59af35c935f894d4
ToppCell	3'-GW_trimst-1-SmallIntestine-Neuronal-Glial_immature-Glia_1_(DHH+)\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	OLFML2A RNF130 ADAM12 GFRA3	3.27e-04	185	79	4	dd17025d8c423aa0a451ac7f1f301c93528e0229
ToppCell	Control-Endothelial-Endothelial-Artery\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	PCSK5 SERTAD4 LRP1B DKK2	3.34e-04	186	79	4	2d3a975d2bf92e18e3410dd413fc9f84831d82de
ToppCell	PCW_07-8.5-Mesenchymal-Mesenchymal_fibroblastic-mes_Arw_fibro_(16)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	DPYD FBN1 FBN2 SERTAD4	3.34e-04	186	79	4	4d68ee3d32f7ef884faf402ef92b31b0eb4656f1
ToppCell	droplet-Lung-21m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell-pulmonary_artery_endothelial_cell_l27\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	PCSK5 FBN1 DKK2 RUFY4	3.34e-04	186	79	4	c116cc9f41971622264434ebe29d18e719b0ae19
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST-Inh_L3-5_SST_MAFB\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	PCSK5 GAD2 FBN2 KCP	3.34e-04	186	79	4	96f6603cc75fa1ffc2a2fdb94ec0ec09498e540a
ToppCell	droplet-Pancreas-Endocrine-21m-Epithelial-pancreatic_A_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RNF130 GC ANO3 GFRA3	3.34e-04	186	79	4	16092819e9148dfe64f07c737652b6e533e699f7
ToppCell	TCGA-Kidney-Primary_Tumor-Renal_Cell_Carcinoma-Kidney_Clear_Cell_Renal_Carcinoma-2\|TCGA-Kidney / Sample_Type by Project: Shred V9	OLFML2A FBN1 TTYH2 ADAM12	3.34e-04	186	79	4	1e6526fc9e9381b7ace864588cc7bd80194338d6
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	PCSK5 GAD2 FBN2 KCP	3.40e-04	187	79	4	85f1678338a47d91e296f0620d4887f057eb7e70
ToppCell	droplet-Trachea-3m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l20-25\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	FBN1 PALM FST DKK2	3.40e-04	187	79	4	0d4b7da81036c2aa678654b9fe49c939d08fcd9b
ToppCell	3'-Adult-LargeIntestine-Hematopoietic-Myeloid-Lymphoid_DC\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	FAM72C TTYH2 BIRC3 SLC16A8	3.40e-04	187	79	4	d69f4eee0304a7db226275ab77fc9d5d2b6f3a07
ToppCell	droplet-Kidney-nan-18m-Epithelial-Pecam____Kidney_cortex_artery_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PCSK5 GAD2 FBN1 DKK2	3.40e-04	187	79	4	e93cad16a087d1443cbf4e1690dc1b35d7a84c41
ToppCell	Multiple_Sclerosis-Lymphocyte-T_NK-T_NK_proliferative\|Multiple_Sclerosis / Disease, Lineage and Cell Type	FAM72D FAM72C GFRA3 FAM72B	3.47e-04	188	79	4	6c05797a5d0635d89ffcf4aca52178687129ccb4
ToppCell	droplet-Pancreas-Endocrine-18m-Epithelial-pancreatic_A_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC24A5 RNF130 GC GFRA3	3.54e-04	189	79	4	ce3fbaf9642785c8adf6edaeae20998bca558928
ToppCell	E18.5-Endothelial-Endothelial_blood-vessel-Macrovascular_EC\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PCSK5 FBN1 CXXC4 DKK2	3.54e-04	189	79	4	d17e8467699c7ca7694a313c26111f085df5204e
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L2-4_PVALB_C8orf4\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	GAD2 EYS MINAR1 WFDC8	3.54e-04	189	79	4	99a13b1b669b0cd36e3096632351d9ade25d1173
ToppCell	RV-15._Ventricular_Cardiomyocyte_III\|World / Chamber and Cluster_Paper	TNFRSF12A FBN2 KCP ATP11A	3.54e-04	189	79	4	0a82931b5f6c0a6427ca3edd5e2235ac49099d40
ToppCell	facs-Thymus-Flowthrough-24m-Mesenchymal-fibroblast\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TNFRSF12A SNX7 FST DKK2	3.62e-04	190	79	4	990ac07f4b0a22041daac7502f74fafd6d258cba
ToppCell	LPS-IL1RA-Endothelial-Endothelial-Artery\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	PCSK5 FBN1 SERTAD4 DKK2	3.62e-04	190	79	4	aed65d584ca0c25f6a8313c66b421a6618af82ea
ToppCell	facs-Thymus-Flowthrough-24m-Mesenchymal-fibroblast\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TNFRSF12A SNX7 FST DKK2	3.62e-04	190	79	4	fc9bbe5e6e0ec3cfa47bf479d8b09a0fc53169cc
ToppCell	facs-Thymus-Flowthrough-24m-Mesenchymal\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TNFRSF12A SNX7 FST DKK2	3.62e-04	190	79	4	39ecdf8815e235771132684dfc1aff1917e20965
ToppCell	droplet-Pancreas-Endocrine-18m-Epithelial-pancreatic_A_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC24A5 RNF130 GC GFRA3	3.62e-04	190	79	4	db19c72d8c8053262b535068c5a9d4d696989cb1
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L2-4_PVALB_C8orf4\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	GAD2 EYS MINAR1 FST	3.62e-04	190	79	4	e58e4b6fbeb4368f738adac67ec10879c0966f0f
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST-Inh_L2-4_SST_AHR\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	PCSK5 GAD2 EYS MINAR1	3.69e-04	191	79	4	782bc7946417549ffd39e5b596db659436fa01ba
ToppCell	facs-Trachea-3m-Mesenchymal-fibroblast-fibroblast_of_trachea-tracheal_fibroblast_l20-25\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	OLFML2A FBN1 TTYH2 ANO3	3.76e-04	192	79	4	30cefa0990ba1f379f350bfbf994a78db145075e
ToppCell	E15.5-Epithelial\|E15.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	TNFRSF12A FBN2 SNX7 STARD10	3.76e-04	192	79	4	3f2ecd428c0c608d7bbd7b403a07399b87761338
ToppCell	3'-GW_trimst-2-SmallIntestine-Epithelial-neuro-epithelial\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	GAD2 STARD10 GC GFRA3	3.76e-04	192	79	4	0b506fb5bca54a50949932293c6f86d974a3acdd
ToppCell	PND14-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	TTYH2 KCP LRRC4C FST	3.76e-04	192	79	4	158cc5736f154da1cb3186ffbf186eae10483e48
Disease	connective tissue disease (implicated_via_orthology)	FBN1 FBN2	1.86e-05	3	74	2	DOID:65 (implicated_via_orthology)
Disease	Liver Failure, Acute	GC ALB FST	2.95e-05	24	74	3	C0162557
Disease	scoliosis (is_implicated_in)	FBN1 FBN2	3.71e-05	4	74	2	DOID:0060249 (is_implicated_in)
Disease	psychosocial stress measurement	EYS FST	3.36e-04	11	74	2	EFO_0006783
Disease	severe aplastic anemia	DPYD FBN2	6.38e-04	15	74	2	EFO_0006927
Disease	p-tau measurement	LRRC4C FST ANO3	7.98e-04	72	74	3	EFO_0004763
Disease	hepatocellular carcinoma (is_implicated_in)	BIRC3 GC ALB LRP1B	1.13e-03	181	74	4	DOID:684 (is_implicated_in)
Disease	pulmonary arterial hypertension	SLC24A5 FBN1	1.39e-03	22	74	2	EFO_0001361
Disease	carnosine measurement	ZNF675 LRRC4C	1.65e-03	24	74	2	EFO_0010470
Disease	intraocular pressure measurement	PCSK5 TTF2 FBN1 FBN2 FST ADAM12	1.76e-03	509	74	6	EFO_0004695
Disease	hemoglobin A1 measurement	GAD2 ATP11B RP1L1 ATP11A ANO3 ELOF1	1.96e-03	520	74	6	EFO_0007629
Disease	Acute Kidney Insufficiency	TNFRSF12A GC ALB	2.12e-03	101	74	3	C1565662
Disease	Acute kidney injury	TNFRSF12A GC ALB	2.12e-03	101	74	3	C2609414
Disease	Kidney Failure, Acute	TNFRSF12A GC ALB	2.12e-03	101	74	3	C0022660
Disease	Liver Cirrhosis	FBN1 GC ALB	2.24e-03	103	74	3	C0023890
Disease	Fibrosis, Liver	FBN1 GC ALB	2.36e-03	105	74	3	C0239946
Disease	central nervous system cancer, glioma	MDM4 SLC16A8	2.41e-03	29	74	2	EFO_0000326, EFO_0005543

Protein segments in the cluster

Peptide	Gene	Start	Entry
CNREREIFMSKCAKC	ERC2-IT1	121	O76042
CCKHPEAKRMPCAED	ALB	461	P02768
TCPCCNMRKKDAVLT	RNF20	921	Q5VTR2
CCKDCKFMPSGELCR	ADAM21	451	Q9UKJ8
NDKVKCFCCGLMLDN	BIRC3	61	Q13489
AKCEMRDAKCGKIQC	ADAM12	571	O43184
AMRCLKCADAPCQKS	DPYD	76	Q12882
KKKRCHRDGMCCPST	DKK2	106	Q9UBU2
CRAPCDRLMRQCKGD	DIPK1B	346	Q5VUD6
CPFCNHEKSCDVKMD	ELOF1	26	P60002
MCPLCDKNCSLQRLN	ANO3	441	Q9BYT9
PEARKAINCMSLSKC	NWD1	1296	Q149M9
PQDLDMKKHRCKCCS	PALM	371	O75781
SEHCTCPMCKLNILK	RNF130	296	Q86XS8
FMAVATNCCLRCAKA	SLC16A8	426	O95907
AAARKAACACDQKPC	GAD2	66	Q05329
MCHNKVCIPKQFVCD	LRP1B	2811	Q9NZR2
CKIKINDCTSIPCMN	EYS	1076	Q5T1H1
EKLILPSHMACCLCQ	LRRC37A2	1016	A6NM11
EKLILPSHMACCLCQ	LRRC37A	1016	A6NMS7
IKPLCTKMAFLCAAC	MCM8	231	Q9UJA3
NMEDCQNLLKPCSLC	MDM4	426	O15151
LCCKFCKQVLSSRGM	FAM72D	16	Q6L9T8
ADKKRCRKCAPNCES	PCSK5	681	Q92824
TFMCDKRCNKKRLCG	NFX1	681	Q12986
AAKAKFLCIMCCSNI	LACC1	36	Q8IV20
EKLILPSHMACCLCQ	LRRC37B	706	Q96QE4
IKDMAPSNTACCARC	LRRC4C	316	Q9HCJ2
CRMNKKNKPRCVCAP	FST	106	P19883
LCCKFCKQVLSSRGM	FAM72A	16	Q5TYM5
CCDLQPLLKLACMDT	OR4C11	176	Q6IEV9
CRQECKKSCPVVRMG	ABCE1	21	P61221
KQCAEAVDRCPMCSA	BIRC8	211	Q96P09
KCKHEFCAPCINKAM	DTX3L	576	Q8TDB6
LCLKFAMLCTLNDKC	GFRA3	161	O60609
MCINEDGSFKCICKP	FBN1	586	P35555
ECKMIPSLCTHGKCR	FBN1	1031	P35555
CKICCCRAMKKGAVL	CHAMP1	711	Q96JM3
LCCKFCKQVLSSRGM	FAM72C	16	H0Y354
HCRPLAGECMNKLKC	CXXC4	36	Q9H2H0
LCLACRNMSKAEAVC	HSD17B7	31	P56937
MCINEDGSFKCICKP	FBN2	631	P35556
MTPCLESFCQRAKDC	LINC01554	1	Q52M75
KKNRCANCFDCPGCM	DCTN4	66	Q9UJW0
LCCKFCKQVLSSRGM	FAM72B	16	Q86X60
DCRCKCIMRPLSKDA	OLFML2A	46	Q68BL7
SKCRKMDCKDCPQFV	MINAR1	156	Q9UPX6
SFMLPCNHSLCEKCL	TRIM42	156	Q8IWZ5
HKIKCRMECCDVPAE	STARD10	66	Q9Y365
TCTKCGKRMNECPIC	RFFL	336	Q8WZ73
LCTCQEGSMRCQKKP	KCP	866	Q6ZWJ8
HRTCPMCKCDILKAL	RNF128	311	Q8TEB7
HACSMDYKKRDRCCP	RUFY4	546	Q6ZNE9
CLCGKDMSHVKAACI	SLC5A4	301	Q9NY91
PRMAKEECEKFHACC	SERTAD4	176	Q9NUC0
ASCIDRCCKATEKRM	SNX7	246	Q9UNH6
CQEMAKKGCRHLVCS	SDSL	56	Q96GA7
CNKRCKCDPNMCTNR	SETDB1	781	Q15047
CSAVLCCRMAPLQKA	ATP11A	791	P98196
NCSAVLCCRMAPLQK	ATP11B	786	Q9Y2G3
LQAKETFCPECKMLC	TRIM69	71	Q86WT6
APATCKLCLMCQKLV	RNF214	651	Q8ND24
DQCTKPRDCPENMKC	WFDC6	46	Q9BQY6
ENMKCCPFSRGKKCL	WFDC6	56	Q9BQY6
EKCCSHCGLKCMDPR	WFDC8	226	Q8IUA0
CRSSPKSMICCNKKS	UHRF1BP1L	476	A0JNW5
FCPCEACVRKKVSPM	RP1L1	1656	Q8IWN7
KRSKCLLASMLCCGA	TTYH2	236	Q9BSA4
RRMACTCPNCKDGEK	SP2	501	Q02086
KMFCEVDKSLLCLPC	TRIM51	101	Q9BSJ1
CCTKEGLERKLCMAA	GC	111	P02774
KKCSPCCACLAKAME	SLC24A5	226	Q71RS6
KCPECENSLKLIRCM	TTC17	721	Q96AE7
PFKCKECGRSFCMLS	ZNF675	171	Q8TD23
CKECGKSFCMLPHLA	ZNF43	176	P17038
PMCEKCRKDSCQEAA	ZNF483	411	Q8TF39
LDKCMDCASCRARPH	TNFRSF12A	46	Q9NP84
LAKHPCNASMECDKC	ZNF330	31	Q9Y3S2
ARMMPCKCDIAGSAC	ZNF782	131	Q6ZMW2
PFKCEFCDVRCTMKA	ZFP64	441	Q9NTW7
CCCHLSLLKSALDPM	TTF2	926	Q9UNY4
DSQAPQMKRAPRCCC	PRO3102	41	Q9H379
QMKRAPRCCCLAVVA	PRO3102	46	Q9H379
NNMKSACEKRLGCCS	N4BP1	536	O75113