Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionaspartic-type endopeptidase activity

ERVK-6 ERVK-7 ERVK-21 ERVK-9 ERVK-10 ERVK-8 ERVK-18 ERVK-19 ERVK-25 ERVK-24

2.09e-133715810GO:0004190
GeneOntologyMolecularFunctionaspartic-type peptidase activity

ERVK-6 ERVK-7 ERVK-21 ERVK-9 ERVK-10 ERVK-8 ERVK-18 ERVK-19 ERVK-25 ERVK-24

2.82e-133815810GO:0070001
GeneOntologyMolecularFunctionzinc ion binding

ERVK-6 ZSWIM8 TRAF1 MYCBP2 UBR4 KAT6A ZIM2 MYRIP SLC39A4 ZNF385B ZNF318 ERVK-7 ERVK-21 ERVK-9 ERVK-10 ZCCHC2 ZFPM2 ZCCHC14 BMP1 RASGRP1 GLI2 RNF146 SEC24B ERVK-8 ERVK-5 KMT2A ERVK-19 ERVK-24 TOP3A

7.58e-1189115829GO:0008270
GeneOntologyMolecularFunctiontransition metal ion binding

ERVK-6 ZSWIM8 TRAF1 MYCBP2 UBR4 KAT6A ZIM2 MYRIP SLC39A4 ZNF385B ZNF318 ERVK-7 ERVK-21 ERVK-9 ERVK-10 ZCCHC2 ZFPM2 ZCCHC14 BMP1 RASGRP1 GLI2 RNF146 SEC24B ERVK-8 ERVK-5 KMT2A ERVK-19 ERVK-24 TOP3A

5.23e-08118915829GO:0046914
GeneOntologyMolecularFunctionRNA-DNA hybrid ribonuclease activity

ERVK-6 ERVK-7 ERVK-10 ERVK-8

1.19e-06111584GO:0004523
GeneOntologyMolecularFunctionRNA-directed DNA polymerase activity

ERVK-6 ERVK-7 ERVK-10 ERVK-8

3.55e-06141584GO:0003964
GeneOntologyMolecularFunctionRNA stem-loop binding

ERVK-6 ERVK-7 ERVK-10 ERVK-8

2.03e-05211584GO:0035613
GeneOntologyMolecularFunctionendonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters

ERVK-6 ERVK-7 ERVK-10 FAN1 ERVK-8

3.07e-05461585GO:0016893
GeneOntologyMolecularFunctioncatalytic activity, acting on DNA

ERVK-6 TWNK BTAF1 ERVK-7 ERVK-10 FAN1 BPTF ERVK-8 NAV2 TOP3A

4.64e-0526215810GO:0140097
GeneOntologyMolecularFunctionendopeptidase activity

ERVK-6 ERVK-7 ERVK-21 ERVK-9 ERVK-10 BMP1 ERVK-8 ERVK-18 C2 ERVK-19 ERVK-25 ERVK-24

1.66e-0443015812GO:0004175
GeneOntologyMolecularFunctionhistone H3K9 acetyltransferase activity

KAT6A KAT2B

1.86e-0431582GO:0043992
GeneOntologyMolecularFunctionRNA endonuclease activity, producing 5'-phosphomonoesters

ERVK-6 ERVK-7 ERVK-10 ERVK-8

2.03e-04371584GO:0016891
GeneOntologyMolecularFunctionhistone H3 acetyltransferase activity

KAT6A KAT2B KAT6B

2.06e-04151583GO:0010484
GeneOntologyMolecularFunctionDNA polymerase activity

ERVK-6 ERVK-7 ERVK-10 ERVK-8

2.26e-04381584GO:0034061
GeneOntologyMolecularFunctioncalcium, potassium:sodium antiporter activity

SLC24A5 SLC24A4

6.13e-0451582GO:0008273
GeneOntologyMolecularFunctionstructural molecule activity

ERVK-6 SPTBN2 OBSCN KRTAP29-1 ERVK-7 ERVK-21 ERVK-9 ERVK-10 DCN ERVK-8 ERVK-18 ERVK-5 ERVK-19 ERVK-25 DMBT1 ERVK-24 MUC6

7.11e-0489115817GO:0005198
GeneOntologyMolecularFunctionpeptidase activity

USP53 ERVK-6 ERVK-7 ERVK-21 ERVK-9 ERVK-10 BMP1 ERVK-8 ERVK-18 C2 ERVK-19 ERVK-25 USP54 ERVK-24

7.14e-0465415814GO:0008233
GeneOntologyBiologicalProcessDNA integration

ERVK-6 ERVK-7 ERVK-10 ERVK-8

2.13e-06131564GO:0015074
GeneOntologyBiologicalProcesscentral nervous system development

GAK KIF1A MYCBP2 CENPF SPTBN2 GRN VPS54 ARHGAP35 ATXN1L PITPNM1 SHROOM4 BPTF OTP CDK5R1 GLI2 GLI3 SEC24B LRP1 NAV2 NHEJ1 CPLANE1 ANAPC7 NPAS2

3.47e-05119715623GO:0007417
MousePhenoabnormal right lung accessory lobe morphology

ZFPM2 GLI2 GLI3

6.40e-0651223MP:0009571
MousePhenoomphalocele

ARHGAP35 RUNX1T1 ATXN1L GLI3 SEC24B LRP1

6.41e-06531226MP:0003052
MousePhenoabnormal abdominal wall morphology

ARHGAP35 RUNX1T1 ATXN1L BMP1 GLI3 SEC24B LRP1

7.17e-06821227MP:0003257
MousePhenoherniated abdominal wall

BMP1 GLI3 SEC24B LRP1

2.40e-05201224MP:0000757
MousePhenoabnormal body wall morphology

ARHGAP35 RUNX1T1 ATXN1L REXO1 BMP1 GLI3 SEC24B LRP1

5.24e-051511228MP:0003385
MousePhenoabnormal renal tubule epithelium morphology

GLIS3 ARHGAP35 DCN FAN1 CPLANE1

5.91e-05481225MP:0009640
MousePhenoabnormal right lung middle lobe morphology

ZFPM2 GLI3

7.55e-0521222MP:0009573
MousePhenoabsent right lung accessory lobe

ZFPM2 GLI2

7.55e-0521222MP:0010824
MousePhenoabnormal lung lobe morphology

ZFPM2 GLI2 GLI3 SEC24B

1.86e-04331224MP:0010975
MousePhenoabnormal kidney epithelium morphology

GLIS3 ARHGAP35 DCN FAN1 CPLANE1

1.88e-04611225MP:0004967
Domainzf-CCHC

ERVK-6 ZCCHC2 ZCCHC14 ERVK-5

2.90e-05231474PF00098
DomainCUB

KREMEN2 MFRP CSMD2 BMP1 DMBT1

4.07e-05491475PF00431
DomainCUB

KREMEN2 MFRP CSMD2 BMP1 DMBT1

4.49e-05501475SM00042
Domain-

KREMEN2 MFRP CSMD2 BMP1 DMBT1

5.44e-055214752.60.120.290
DomainCUB

KREMEN2 MFRP CSMD2 BMP1 DMBT1

5.97e-05531475PS01180
DomainZnF_C2HC

ERVK-6 ZCCHC2 ZCCHC14 ERVK-5 TOP3A

7.15e-05551475SM00343
DomainZnf_CCHC

ERVK-6 ZCCHC2 ZCCHC14 ERVK-5 TOP3A

7.15e-05551475IPR001878
DomainCUB_dom

KREMEN2 MFRP CSMD2 BMP1 DMBT1

8.50e-05571475IPR000859
DomainZF_CCHC

ERVK-6 ZCCHC2 ZCCHC14 ERVK-5

1.60e-04351474PS50158
Pubmed

A revised nomenclature for transcribed human endogenous retroviral loci.

ERVK-6 ERVK-7 ERVK-21 ERVK-9 ERVK-10 ERVK-8 ERVK-18 ERVK-5 ERVK-19 ERVK-25 ERVK-24

6.86e-13941601121542922
Pubmed

Quantitation of HERV-K env gene expression and splicing in human breast cancer.

ERVK-6 ERVK-7 ERVK-21 ERVK-18 ERVK-19

1.94e-125160512629516
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

USP53 JCAD SYNRG ARHGAP32 HIVEP2 TTC28 MYCBP2 MLXIP PFKP MAP3K6 ZCCHC14 ZNF106 MTMR4 PTPN13 SEC24B NAV2 KMT2A TNKS1BP1 USP54 PLCH1 PHLDB2 CRTC2

8.54e-118611602236931259
Pubmed

Expression patterns of transcribed human endogenous retrovirus HERV-K(HML-2) loci in human tissues and the need for a HERV Transcriptome Project.

ERVK-21 ERVK-9 ERVK-10 ERVK-18 ERVK-25 ERVK-24

1.53e-1018160618664271
Pubmed

Many human endogenous retrovirus K (HERV-K) proviruses are unique to humans.

ERVK-6 ERVK-7 ERVK-10 ERVK-24

4.31e-104160410469592
Pubmed

Human endogenous retrovirus K10: expression of Gag protein and detection of antibodies in patients with seminomas.

ERVK-6 ERVK-10 ERVK-5 ERVK-19

4.31e-10416047983737
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

SEC16B ARHGAP32 CTTNBP2 SPTBN2 TOGARAM1 ZBTB26 ZCCHC2 ARHGAP35 REXO1 FAN1 SHROOM4 KRBA1 FAT2 PLCH1 MAML3 UNC80

1.31e-094931601615368895
Pubmed

Genomewide screening for fusogenic human endogenous retrovirus envelopes identifies syncytin 2, a gene conserved on primate evolution.

ERVK-6 ERVK-21 ERVK-9 ERVK-8 ERVK-19

1.49e-0912160514557543
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

EPHB4 SYNRG HIVEP2 MYCBP2 UBR4 KAT6A OBSCN TWNK BTAF1 MLXIP ARHGAP35 ANKHD1 REXO1 GGA3 PCNX2 ZCCHC14 STK10 CDK5R1 NAV2 TNKS1BP1 SNAPC4 FEM1A TOP3A

1.63e-0911051602335748872
Pubmed

A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration.

NRIP1 ZSWIM8 ARHGAP32 TRAF1 KAT6A GRN RUNX1T1 ANKHD1 ATXN1L TXNDC11 ZFPM2 DZIP3 YY1AP1 USP54 KAT6B RAI2 TGS1

3.64e-096081601716713569
Pubmed

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.

USP53 NRIP1 HIVEP2 KIF1A MYCBP2 SLC38A9 KAT6A OBSCN MYRIP BARD1 ZNF385B BTAF1 VPS54 ARHGAP35 DNAH1 PCNX2 STK10 BPTF PTPN13 GLI2 SETBP1 LRP1 ANKRD12 KAT6B MAML3 NPAS2

4.97e-0914891602628611215
Pubmed

Large-scale characterization of HeLa cell nuclear phosphoproteins.

SEC16B SYNRG MYCBP2 BTAF1 ZNF318 ARHGAP35 PFKP REXO1 PITPNM1 STK10 BPTF ZNF106 KMT2A YY1AP1 TNKS1BP1 SNAPC4 KAT6B PHLDB2

2.11e-087741601815302935
Pubmed

Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.

NRIP1 TTC28 MYCBP2 CENPF ZSCAN4 UBR4 RUSC1 ZNF318 POU5F1B ANKHD1 PTPN13 LRP1 TNKS1BP1

8.06e-084181601334709266
Pubmed

Genome-wide screening, cloning, chromosomal assignment, and expression of full-length human endogenous retrovirus type K.

ERVK-6 ERVK-18 ERVK-19

9.56e-083160310516026
Pubmed

Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.

TTC28 MYCBP2 TOGARAM1 ARHGAP35 ZCCHC14 SETBP1 NAV2 TNKS1BP1 KAT6B UNC80

1.03e-072251601012168954
Pubmed

SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.

SYNRG GAK TTC28 MYCBP2 SPTBN2 ZNF318 ARHGAP35 ANKHD1 GGA3 BPTF PTPN13 SEC24B KMT2A TNKS1BP1

2.84e-075491601438280479
Pubmed

Transcriptionally active HERV-K genes: identification, isolation, and chromosomal mapping.

ERVK-6 ERVK-7 ERVK-5

9.49e-075160311401426
Pubmed

Human endogenous retrovirus HERV-K(HML-2) proviruses with Rec protein coding capacity and transcriptional activity.

ERVK-6 ERVK-9 ERVK-19

1.89e-066160315063128
Pubmed

Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.

JCAD NRIP1 ZSWIM8 HIVEP2 TTC28 KIF1A MYCBP2 SPTBN2 UBR4 MYRIP VPS54 DCN TXNDC11 FAN1 PTPN13 RCBTB1 LRP1 YY1AP1 USP54 DNAJB2

2.06e-0612851602035914814
Pubmed

Targeting TRIM37-driven centrosome dysfunction in 17q23-amplified breast cancer.

NRIP1 GRN ZNF318 KRBA1 SEC24B LRP1 ANKRD12 PHLDB2

2.37e-06184160832908313
Pubmed

Human transcription factor protein interaction networks.

ARHGAP32 UBR4 PABPC4 TWNK GRN ZNF318 PFKP ANKHD1 ATXN1L INO80D ZFPM2 BPTF KAT2B GLI2 GLI3 SEC24B KMT2A ELAVL2 YY1AP1 USP54 RAI2

2.75e-0614291602135140242
Pubmed

Retinoic acid-stimulated sequential phosphorylation, PML recruitment, and SUMOylation of nuclear receptor TR2 to suppress Oct4 expression.

NRIP1 POU5F1B KAT2B

3.30e-067160318682553
Pubmed

Proteome-scale mapping of binding sites in the unstructured regions of the human proteome.

USP53 JCAD ARHGAP32 UBR4 GLIS3 GGA3 STK10 ZNF469 GLI2 SETBP1 CRTC2

5.42e-064301601135044719
Pubmed

SUMOylation of Tr2 orphan receptor involves Pml and fine-tunes Oct4 expression in stem cells.

NRIP1 POU5F1B KAT2B

7.87e-069160317187077
Pubmed

Gli3 null mice display glandular overgrowth of the developing stomach.

CBLIF GLI2 GLI3

7.87e-069160316247775
Pubmed

Osteocyte transcriptome mapping identifies a molecular landscape controlling skeletal homeostasis and susceptibility to skeletal disease.

STARD13 CTTNBP2 SKIDA1 ZCCHC14

8.10e-0628160433953184
Pubmed

Shotgun sequencing of the human transcriptome with ORF expressed sequence tags.

ZSWIM8 ARHGAP32 KIF1A MLXIP ZCCHC2 ATXN1L GRAMD1B SHROOM4 NAV2 ERVK-25 CPLANE1 UNC80

1.04e-055521601210737800
Pubmed

CD spectra show the relational style between Zic-, Gli-, Glis-zinc finger protein and DNA.

GLIS3 GLI2 GLI3

1.12e-0510160318298960
Pubmed

Survey of human genes of retroviral origin: identification and transcriptome of the genes with coding capacity for complete envelope proteins.

ERVK-6 ERVK-21 ERVK-19

1.12e-0510160312970426
Pubmed

Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.

ZSWIM8 KIF1A MYCBP2 CENPF SPTBN2 UBR4 PABPC4 ZNF318 PFKP ANKHD1 BPTF KMT2A TNKS1BP1

1.13e-056531601322586326
Pubmed

Acetylation of HIV-1 integrase by p300 regulates viral integration.

KAT6A KAT2B KAT6B

1.53e-0511160316096645
Pubmed

Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.

ZSWIM8 TTC28 KAT6A ZNF318 ANKHD1 INO80D BPTF ZNF469 KAT2B GLI3 CAPRIN2 LRP1 USP54 KAT6B ANAPC7 UNC80 PHLDB2

1.67e-0511161601731753913
Pubmed

Local anesthetics impair the growth and self-renewal of glioblastoma stem cells by inhibiting ZDHHC15-mediated GP130 palmitoylation.

ZNF318 CRB1 LRP1 MUC6 UNC80

1.97e-0571160533541421
Pubmed

Congenital diaphragmatic hernia: comparison of animal models and relevance to the human situation.

ZFPM2 GLI2 GLI3

2.04e-0512160319325248
Pubmed

Functional proteomics mapping of a human signaling pathway.

STARD13 MYCBP2 ZSCAN4 UBR4 PABPC4 TWNK GRN GGA3 ZNF106 MTMR4 LRP1 DNAJB2

2.04e-055911601215231748
Pubmed

Co-inheritance of the membrane frizzled-related protein ocular phenotype and glycogen storage disease type Ib.

MFRP SLC37A4

2.10e-052160228511025
Pubmed

Lack of phenotypic effect of triallelic variation in SPATA7 in a family with Leber congenital amaurosis resulting from CRB1 mutations.

SPATA7 CRB1

2.10e-052160222219627
Pubmed

The low density lipoprotein receptor-related protein functions as an endocytic receptor for decorin.

DCN LRP1

2.10e-052160216936287
Pubmed

A novel protein-processing domain in Gli2 and Gli3 differentially blocks complete protein degradation by the proteasome.

GLI2 GLI3

2.10e-052160217283082
Pubmed

New mouse models of congenital anorectal malformations.

GLI2 GLI3

2.10e-052160210693670
Pubmed

ERα status of invasive ductal breast carcinoma as a result of regulatory interactions between lysine deacetylases KAT6A and KAT6B.

KAT6A KAT6B

2.10e-052160239505971
Pubmed

Differential effects of GLI2 and GLI3 in regulating cervical cancer malignancy in vitro and in vivo.

GLI2 GLI3

2.10e-052160229967343
Pubmed

Kinetics of hedgehog-dependent full-length Gli3 accumulation in primary cilia and subsequent degradation.

GLI2 GLI3

2.10e-052160220154143
Pubmed

The double PHD finger domain of MOZ/MYST3 induces α-helical structure of the histone H3 tail to facilitate acetylation and methylation sampling and modification.

KAT6A KAT6B

2.10e-052160224150941
Pubmed

Defective Proteolytic Processing of Fibrillar Procollagens and Prodecorin Due to Biallelic BMP1 Mutations Results in a Severe, Progressive Form of Osteogenesis Imperfecta.

DCN BMP1

2.10e-052160225656619
Pubmed

Normal exon copy number of the GLI2 and GLI3 genes in patients with esophageal atresia.

GLI2 GLI3

2.10e-052160223442119
Pubmed

Expression of human endogenous retrovirus type K envelope glycoprotein in insect and mammalian cells.

ERVK-6 ERVK-19

2.10e-05216029060628
Pubmed

Evolutionary relationships within a subgroup of HERV-K-related human endogenous retroviruses.

ERVK-6 ERVK-19

2.10e-05216029460924
Pubmed

Regulation of KAT6 Acetyltransferases and Their Roles in Cell Cycle Progression, Stem Cell Maintenance, and Human Disease.

KAT6A KAT6B

2.10e-052160227185879
Pubmed

A Functional Study of Mutations in K+-dependent Na+-Ca2+ Exchangers Associated with Amelogenesis Imperfecta and Non-syndromic Oculocutaneous Albinism.

SLC24A5 SLC24A4

2.10e-052160227129268
Pubmed

Adult Gli2+/-;Gli3Δ699/+ Male and Female Mice Display a Spectrum of Genital Malformation.

GLI2 GLI3

2.10e-052160227814383
Pubmed

KAT6A is associated with sorafenib resistance and contributes to progression of hepatocellular carcinoma by targeting YAP.

KAT6A YY1AP1

2.10e-052160234808502
Pubmed

Interferon-alpha-induced endogenous superantigen. a model linking environment and autoimmunity.

ERVK-6 ERVK-18

2.10e-052160211672541
Pubmed

Decorin is processed by three isoforms of bone morphogenetic protein-1 (BMP1).

DCN BMP1

2.10e-052160220026052
Pubmed

A study on etiology of incontinence in double knockout mouse model.

GLI2 GLI3

2.10e-052160236272934
Pubmed

A genome-wide screen to identify transcription factors expressed in pelvic Ganglia of the lower urinary tract.

HIVEP2 KIF1A ZNF318 ZCCHC14 OTP RCBTB1 GLI2 GLI3 RNF146 KMT2A KAT6B MAML3 TOP3A

2.66e-057091601322988430
Pubmed

RNF43 inhibits WNT5A-driven signaling and suppresses melanoma invasion and resistance to the targeted therapy.

ARHGAP32 TTC28 ZNF318 GGA3 PTPN13 GLI3 SEC24B USP54

3.19e-05263160834702444
Pubmed

In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.

STARD13 CACNA1E CENPF SPTBN2 UBR4 BIVM PABPC4 SKIDA1 MYRIP TWNK ZNF318 PFKP BPTF CAPRIN2 NAV2 KMT2A NGLY1 PLCH1 ANAPC7

3.83e-0514421601935575683
Pubmed

Identification and Characterization of K(+)-Dependent Na(+)-Ca(2+) Exchange Transport in Pigmented MEB4 Cells Mediated by NCKX4.

SLC24A5 SLC24A4

6.29e-053160227093457
Pubmed

Murine models of VACTERL syndrome: Role of sonic hedgehog signaling pathway.

GLI2 GLI3

6.29e-053160211172440
Pubmed

Fuzzy modeling reveals a dynamic self-sustaining network of the GLI transcription factors controlling important metabolic regulators in adult mouse hepatocytes.

GLI2 GLI3

6.29e-053160226010061
Pubmed

Acetylation of nuclear hormone receptor-interacting protein RIP140 regulates binding of the transcriptional corepressor CtBP.

NRIP1 KAT2B

6.29e-053160211509661
Pubmed

Identification of an active reverse transcriptase enzyme encoded by a human endogenous HERV-K retrovirus.

ERVK-6 ERVK-9

6.29e-05316029971820
Pubmed

Gene expression profiling reveals the heterogeneous transcriptional activity of Oct3/4 and its possible interaction with Gli2 in mouse embryonic stem cells.

POU5F1B GLI2

6.29e-053160224121003
Pubmed

Colorectal cancer susceptibility variants alter risk of breast cancer in a Chinese Han population.

POU5F1B PTPN13

6.29e-053160224338422
Pubmed

Tandem PHD fingers of MORF/MOZ acetyltransferases display selectivity for acetylated histone H3 and are required for the association with chromatin.

KAT6A KAT6B

6.29e-053160223063713
Pubmed

Zscan4: a novel gene expressed exclusively in late 2-cell embryos and embryonic stem cells.

ZSCAN4 POU5F1B

6.29e-053160217553482
Pubmed

Gli family members are differentially expressed during the mitotic phase of spermatogenesis.

GLI2 GLI3

6.29e-05316029178901
Pubmed

Crystal structure of a five-finger GLI-DNA complex: new perspectives on zinc fingers.

GLI2 GLI3

6.29e-05316028378770
Pubmed

MORF and MOZ acetyltransferases target unmethylated CpG islands through the winged helix domain.

KAT6A KAT6B

6.29e-053160236754959
Pubmed

A mouse model of greig cephalopolysyndactyly syndrome: the extra-toesJ mutation contains an intragenic deletion of the Gli3 gene.

GLI2 GLI3

6.29e-05316028387379
Pubmed

Positive regulation of Hedgehog signaling via phosphorylation of GLI2/GLI3 by DYRK2 kinase.

GLI2 GLI3

6.29e-053160238968120
Pubmed

Unique and complimentary activities of the Gli transcription factors in Hedgehog signaling.

GLI2 GLI3

6.29e-053160216571352
Pubmed

The internal region leucine-rich repeat 6 of decorin interacts with low density lipoprotein receptor-related protein-1, modulates transforming growth factor (TGF)-β-dependent signaling, and inhibits TGF-β-dependent fibrotic response in skeletal muscles.

DCN LRP1

6.29e-053160222203668
Pubmed

Different expression patterns of Gli1-3 in mouse embryonic maxillofacial development.

GLI2 GLI3

6.29e-053160222178118
Pubmed

Presence of rd8 mutation does not alter the ocular phenotype of late-onset retinal degeneration mouse model.

MFRP CRB1

6.29e-053160225814825
Pubmed

Multiple Ser/Thr-rich degrons mediate the degradation of Ci/Gli by the Cul3-HIB/SPOP E3 ubiquitin ligase.

GLI2 GLI3

6.29e-053160219955409
Pubmed

A novel modulatory mechanism of transforming growth factor-beta signaling through decorin and LRP-1.

DCN LRP1

6.29e-053160217485468
Pubmed

Sonic hedgehog through Gli2 and Gli3 is required for the proper development of placental labyrinth.

GLI2 GLI3

6.29e-053160225695606
Pubmed

Suppressive effect of receptor-interacting protein 140 on coregulator binding to retinoic acid receptor complexes, histone-modifying enzyme activity, and gene activation.

NRIP1 KAT2B

6.29e-053160214581481
Pubmed

Mouse screen reveals multiple new genes underlying mouse and human hearing loss.

STARD13 SEC16B CTTNBP2 C19orf67 BIVM PABPC4 SKIDA1 KDM4E MFRP DCN PITPNM1 ZCCHC14 CBLIF ZNF106 KAT2B CAPRIN2 SNAPC4

6.32e-0512421601730973865
Pubmed

Loss of Glis3 causes dysregulation of retrotransposon silencing and germ cell demise in fetal mouse testis.

GLIS3 POU5F1B GLI3

8.77e-0519160329941866
Pubmed

Molecular characterization of mutant mouse strains generated from the EUCOMM/KOMP-CSD ES cell resource.

PABPC4 ZNF106 CRTC2

8.77e-0519160323912999
Pubmed

Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability.

NRIP1 SYNRG ZSWIM8 GAK TTC28 ZNF318 ZCCHC2 RIMBP3 YY1AP1 TNKS1BP1 TOP3A

9.44e-055881601138580884
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

TTC28 MLXIP GGA3 GRAMD1B ZCCHC14 TRIL DZIP3 YY1AP1 ANKRD12

1.20e-04407160912693553
Pubmed

Cloning and sequencing of the mouse Gli2 gene: localization to the Dominant hemimelia critical region.

GLI2 GLI3

1.25e-04416029027508
Pubmed

Comparative genomics identification of a novel set of temporally regulated hedgehog target genes in the retina.

GLI2 GLI3

1.25e-044160222281533
Pubmed

Hedgehog pathway dysregulation contributes to the pathogenesis of human gastrointestinal stromal tumors via GLI-mediated activation of KIT expression.

GLI2 GLI3

1.25e-044160227793025
Pubmed

Non-canonical activation of hedgehog in prostate cancer cells mediated by the interaction of transcriptionally active androgen receptor proteins with Gli3.

GLI2 GLI3

1.25e-044160229429990
Pubmed

Expression profile of Gli family members and Shh in normal and mutant mouse limb development.

GLI2 GLI3

1.25e-04416029438426
Pubmed

Expression of three mouse homologs of the Drosophila segment polarity gene cubitus interruptus, Gli, Gli-2, and Gli-3, in ectoderm- and mesoderm-derived tissues suggests multiple roles during postimplantation development.

GLI2 GLI3

1.25e-04416028150204
Pubmed

Acetylation stabilizes ATP-citrate lyase to promote lipid biosynthesis and tumor growth.

UBR4 KAT2B

1.25e-044160223932781
Pubmed

Histone demethylase KDM4D cooperates with NFIB and MLL1 complex to regulate adipogenic differentiation of C3H10T1/2 mesenchymal stem cells.

KDM4E KMT2A

1.25e-044160232080306
Pubmed

The kinesin-4 protein Kif7 regulates mammalian Hedgehog signalling by organizing the cilium tip compartment.

GLI2 GLI3

1.25e-044160224952464
Pubmed

Recognition of accessory protein motifs by the gamma-adaptin ear domain of GGA3.

SYNRG GGA3

1.25e-044160212858162
Pubmed

Recognition of unmodified histone H3 by the first PHD finger of bromodomain-PHD finger protein 2 provides insights into the regulation of histone acetyltransferases monocytic leukemic zinc-finger protein (MOZ) and MOZ-related factor (MORF).

KAT6A KAT6B

1.25e-044160221880731
Pubmed

Mouse suppressor of fused is a negative regulator of sonic hedgehog signaling and alters the subcellular distribution of Gli1.

GLI2 GLI3

1.25e-044160210531011
Pubmed

Relationships between AML1-ETO and MLL-AF9 fusion gene expressions and hematological parameters in acute myeloid leukemia.

RUNX1T1 KMT2A

1.25e-044160233431365
Pubmed

The interaction of ETV6 (TEL) and TIP60 requires a functional histone acetyltransferase domain in TIP60.

KAT6A KAT6B

1.25e-044160217980166
Pubmed

Specific and redundant functions of Gli2 and Gli3 zinc finger genes in skeletal patterning and development.

GLI2 GLI3

1.25e-04416029006072
InteractionYWHAH interactions

USP53 JCAD NRIP1 SYNRG ARHGAP32 HIVEP2 TTC28 MYCBP2 TWNK MLXIP ATXN1L MAP3K6 ZCCHC14 ZNF106 MTMR4 PTPN13 SEC24B NAV2 KMT2A TNKS1BP1 USP54 PLCH1 PHLDB2 CRTC2

1.26e-06110214624int:YWHAH
InteractionTOP3B interactions

EPHB4 SYNRG HIVEP2 MYCBP2 CENPF SPTBN2 UBR4 KAT6A OBSCN TWNK GRN BTAF1 MLXIP ARHGAP35 PFKP ANKHD1 REXO1 GGA3 PCNX2 ZCCHC14 STK10 CDK5R1 SEC24B NAV2 TNKS1BP1 SNAPC4 FEM1A TOP3A

2.06e-06147014628int:TOP3B
InteractionEGLN3 interactions

JCAD ZSWIM8 ARHGAP32 MYCBP2 CENPF UBR4 BTAF1 ZNF318 ANKHD1 ZFPM2 ZCCHC14 ZNF106 PTPN13 GLI2 GLI3 SEC24B TNKS1BP1 PRR14L USP54 PLCH1 FEM1A ANAPC7 TOP3A CRTC2 TGS1

6.39e-06129614625int:EGLN3
InteractionCELA1 interactions

ZNF318 KRBA1 GLI3 USP54

2.51e-05241464int:CELA1
GeneFamilyZinc fingers C2HC-type|PHD finger proteins|Lysine acetyltransferases

KAT6A ZFPM2 KAT6B

7.26e-051694366
GeneFamilyZinc fingers ZZ-type|Lysine acetyltransferases

KAT6A KAT2B KAT6B

8.78e-0517943486
GeneFamilyZinc fingers C2H2-type|ZF class homeoboxes and pseudogenes

HIVEP2 ZSCAN4 GLIS3 ZIM2 ZBTB26 ZNF318 ZFPM2 ZNF106 ZNF469 KLF1 GLI2 GLI3

3.39e-04718941228
GeneFamilyPHD finger proteins

KAT6A BPTF KMT2A KAT6B

1.24e-039094488
GeneFamilyRho GTPase activating proteins|BCH domain containing

STARD13 ARHGAP32 ARHGAP35

2.24e-0350943721
CoexpressionDAZARD_RESPONSE_TO_UV_NHEK_DN

NRIP1 HIVEP2 CENPF KAT6A TOGARAM1 ZNF318 ZCCHC14 BPTF FAT2 KAT6B NPAS2

1.17e-0630014811M8702
CoexpressionGSE39916_B_CELL_SPLEEN_VS_PLASMA_CELL_BONE_MARROW_DN

TRAF1 GLIS3 GRN ATXN1L IL18RAP GRAMD1B CDK5R1 PTPN13 DNAJB2

2.15e-062001489M9272
CoexpressionMURARO_PANCREAS_BETA_CELL

HIVEP2 KIF1A MYCBP2 GLIS3 TOGARAM1 ZNF318 ARHGAP35 RUNX1T1 ZCCHC14 ZNF106 RASGRP1 KAT2B CDK5R1 SETBP1 NAV2 ANKRD12 KAT6B UNC80

6.88e-0694614818M39169
CoexpressionDACOSTA_UV_RESPONSE_VIA_ERCC3_DN

STARD13 NRIP1 HIVEP2 TTC28 MYCBP2 CENPF KAT6A BARD1 TOGARAM1 BTAF1 ARHGAP35 STK10 BPTF PTPN13 SEC24B KAT6B MYBL1

7.25e-0685614817M4500
CoexpressionGSE29618_PRE_VS_DAY7_FLU_VACCINE_MDC_UP

USP53 SPTBN2 TOGARAM1 RUNX1T1 INO80D CDK5R1 PTPN13 ANKRD12

1.69e-051971488M4980
CoexpressionGSE29618_PRE_VS_DAY7_POST_TIV_FLU_VACCINE_MDC_UP

USP53 NRIP1 CENPF TOGARAM1 INO80D CDK5R1 PTPN13 RNF146

1.82e-051991488M5009
CoexpressionBUSSLINGER_GASTRIC_IMMUNE_CELLS

SYNRG TRAF1 HIVEP2 MYCBP2 UBR4 KAT6A RCSD1 BTAF1 ARHGAP35 IL18RAP INO80D PCNX2 STK10 BPTF RASGRP1 KAT2B DZIP3 KMT2A NGLY1 EDEM1 KAT6B MYBL1

3.41e-05149214822M40023
CoexpressionMANNO_MIDBRAIN_NEUROTYPES_HGABA

CACNA1E KIF1A MYCBP2 BIVM RUSC1 ZNF318 ARHGAP35 PFKP RUNX1T1 CSMD2 ZFPM2 OTP CDK5R1 FAT2 RNF146 CAPRIN2 ELAVL2 ANKRD12

5.44e-05110614818M39071
CoexpressionTHAKAR_PBMC_INACTIVATED_INFLUENZA_AGE_21_30YO_RESPONDERS_28DY_DN

TRAF1 GAK UBR4 CLEC7A RUSC1 GRN ATXN1L IL18RAP REXO1 GGA3 DNAH1 PITPNM1 STK10 KRBA1 SMCR5 TOP3A

5.55e-0590514816M40865
CoexpressionGSE25677_MPL_VS_R848_STIM_BCELL_UP

CACNA1E TRAF1 MYCBP2 SLC38A9 GRN GRAMD1B EDEM1

6.13e-051741487M8186
CoexpressionDACOSTA_UV_RESPONSE_VIA_ERCC3_COMMON_DN

STARD13 NRIP1 HIVEP2 MYCBP2 CENPF KAT6A BARD1 BPTF SEC24B KAT6B MYBL1

7.17e-0546614811M13522
CoexpressionZHONG_PFC_C3_ASTROCYTE

CACNA1E SPTBN2 OBSCN PFKP RUNX1T1 BPTF CDK5R1 KMT2A ELAVL2 SNAPC4

7.66e-0538914810M39102
ToppCellCOVID-19-Fibroblasts-Adventitial_FB|COVID-19 / group, cell type (main and fine annotations)

USP53 ADAMTSL1 TTC28 GLIS3 RUNX1T1 DCN ZFPM2 GLI3 SETBP1 NAV2 PHLDB2

3.55e-1118514911a5aebf2b9b05b550d021272731d68af9a6b1229d
ToppCellCOVID-19-Fibroblasts|COVID-19 / group, cell type (main and fine annotations)

USP53 TTC28 GLIS3 RUNX1T1 CSMD2 DCN ZFPM2 GLI2 GLI3 SETBP1 PHLDB2

6.98e-1119714911fb847f2277609c31fffcdf49517243ce0684facf
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ADAMTSL1 RUNX1T1 DCN ZFPM2 GLI2 GLI3 SETBP1 LRP1 NAV2

1.98e-08194149981713e0409e8be695ba5dfdc67a997b33435dd9e
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ADAMTSL1 RUNX1T1 DCN ZFPM2 GLI2 GLI3 SETBP1 LRP1 NAV2

1.98e-081941499627cffe2d448e74fc5df92e74e5b922a73304137
ToppCellCOVID-19-Fibroblasts-Intermediate_pathological_FB|COVID-19 / group, cell type (main and fine annotations)

TTC28 GLIS3 RUNX1T1 CSMD2 DCN GLI2 GLI3 SETBP1 PHLDB2

2.26e-081971499f1c8936986123a3151140c374fcd62d6705c530b
ToppCellAdult-Mesenchymal-matrix_fibroblast_2_cell-D175|Adult / Lineage, Cell type, age group and donor

ADAMTSL1 RUNX1T1 DCN ZFPM2 GLI2 GLI3 SETBP1 PHLDB2

2.61e-0719014987dcca3469f3a3b70db0420cb94f7765f39492f06
ToppCellGlobus_pallidus-Neuronal|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

MYCBP2 SPTBN2 ZNF385B PCNX2 CDK5R1 KMT2A ANKRD12 UNC80

2.61e-071901498416de85d8841dac883faa6f5339b2fb461a09e82
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ADAMTSL1 RUNX1T1 DCN ZFPM2 GLI2 GLI3 LRP1 NAV2

2.72e-071911498a6c57627077fa980b7ec1d3894b5f31bfb11b738
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ADAMTSL1 RUNX1T1 DCN ZFPM2 GLI2 GLI3 LRP1 NAV2

2.72e-0719114988f6d592edc32fdb901af30501d4360512334e8c2
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ADAMTSL1 RUNX1T1 DCN ZFPM2 GLI2 SETBP1 LRP1 NAV2

2.83e-071921498bc84b9ce01b4d826a682842ab8a395dac9b91183
ToppCellEntopeduncular-Neuronal|Entopeduncular / BrainAtlas - Mouse McCarroll V32

CACNA1E MYCBP2 SPTBN2 ZNF385B CDK5R1 ELAVL2 ANKRD12 UNC80

2.83e-0719214984c35e5c28a40b439044797ba1f06cb7c36b2a8de
ToppCellAdult-Mesenchymal-matrix_fibroblast_2_cell|Adult / Lineage, Cell type, age group and donor

ADAMTSL1 RUNX1T1 DCN ZFPM2 GLI2 GLI3 SETBP1 PHLDB2

2.83e-071921498d21f0f577156f17c899b08871046a26b88aea011
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ADAMTSL1 RUNX1T1 DCN ZFPM2 GLI2 SETBP1 LRP1 NAV2

2.83e-0719214980ab1176cfbb0de8dd1f22c6e2c41265cf6c10ee1
ToppCellLA|World / Chamber and Cluster_Paper

CACNA1E GLIS3 DCN PCNX2 GLI2 GLI3 LRP1 NAV2

2.94e-071931498d4bf89437216baf489ea0239136dcedf3b6714af
ToppCellChildren_(3_yrs)-Mesenchymal-matrix_fibroblast_2_cell-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

USP53 DCN ZFPM2 GLI3 SETBP1 NAV2 RAI2 PHLDB2

2.94e-071931498261cafc167c86ab277be4ea7f08b0173e2dde26e
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ADAMTSL1 RUNX1T1 DCN ZFPM2 GLI2 SETBP1 LRP1 NAV2

3.06e-071941498e03ba6caed59fa64d4d9b042593469d4a6a3dc10
ToppCellLA-02._Fibroblast_II|LA / Chamber and Cluster_Paper

USP53 TTC28 GLIS3 DCN ZFPM2 SETBP1 LRP1 NAV2

3.06e-071941498234d1494c114cce77c619708bbcd8d5ce805f19b
ToppCellChildren_(3_yrs)-Mesenchymal-matrix_fibroblast_2_cell-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

ADAMTSL1 TTC28 DCN ZFPM2 GLI2 GLI3 SETBP1 PHLDB2

3.18e-071951498ff0aa455e9844a6d7ae57ff59fb6cea825cf1fc2
ToppCellCOVID-19-kidney-Fibroblast-2|COVID-19 / Disease (COVID-19 only), tissue and cell type

ADAMTSL1 GLIS3 RUNX1T1 ZFPM2 GLI2 SETBP1 NAV2 NPAS2

3.18e-0719514983d62ce1c696f47d4d7eb0c5bb0eec2c24b122bb2
ToppCellPCW_13-14-Mesenchymal|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

TTC28 RUNX1T1 DCN ZFPM2 GLI2 GLI3 SETBP1 LRP1

3.44e-07197149873a2085d2682d636726a5432d572ae2a3fbe1c3f
ToppCellParenchymal-NucSeq|Parenchymal / Cell types per location group and 10X technology with lineage, and cell group designations

STARD13 ARHGAP32 TTC28 GLIS3 ZNF385B PTPN13 NAV2 MAML3

3.58e-0719814981996373bdccc55aac347d349bd22f6aad6d0c668
ToppCellCOVID-19-lung-Fibroblast|lung / Disease (COVID-19 only), tissue and cell type

USP53 GLIS3 RUNX1T1 DCN GLI2 GLI3 SETBP1 NAV2

3.58e-071981498df3de77216f5c5d6141ec44d01c56b942f611838
ToppCell(11)_FOXN4+-(2)_GFP_FOXI1|(11)_FOXN4+ / shred by cell type by condition

NRIP1 MYCBP2 CENPF BPTF ZNF106 PTPN13 ANKRD12 TGS1

3.58e-07198149876d40b8c2f8399725b3a62ee2ae0896559cf91eb
ToppCellBronchial-NucSeq-Stromal-Fibroblastic-Fibro_adventitial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

ADAMTSL1 RUNX1T1 DCN ZFPM2 GLI2 SETBP1 LRP1 PHLDB2

3.86e-072001498ad3fdcef895400f929f2ae12ff9bd85fd46adb3a
ToppCellBronchial-NucSeq-Stromal-Fibroblastic|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

RUNX1T1 DCN ZFPM2 GLI2 SETBP1 LRP1 NAV2 PHLDB2

3.86e-072001498cae972324d1dfea6efeaf6013f265c7c6bb48db4
ToppCellE16.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-SCMF-SCMF_mature|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

STARD13 RCSD1 DCN GRAMD1B NOTUM FEM1A SLC37A4

2.10e-0617514971d8aab491dcc27ea5dbfb6462d18ee280b21a05e
ToppCellE16.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-SCMF|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

STARD13 RCSD1 DCN GRAMD1B NOTUM FEM1A SLC37A4

2.10e-061751497427a7ee92fe16a90625946492062d37aa0f7235b
ToppCellTCGA-Brain-Primary_Tumor-Low_Grade_Glioma|TCGA-Brain / Sample_Type by Project: Shred V9

KIF1A INO80D DZIP3 KMT2A ANKRD12 USP54 KAT6B

2.27e-061771497e8ab340b20cd41554c3841fe980e078e878af35f
ToppCelldroplet-Kidney-KIDNEY-30m-Lymphocytic-Epcam____thick_ascending_tube_S_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CENPF BARD1 TWNK TOGARAM1 MAP3K6 RAI2 MYBL1

2.45e-0617914974166c4e1a8748a79ac6a11fd0b97c5344be2321b
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-kidney_interstitial_fibroblast_5|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

RUNX1T1 DCN ZFPM2 GLI2 GLI3 SETBP1 NAV2

2.93e-061841497c5436a8e45f471b8d1301abbe9c7879204537f52
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ADAMTSL1 RUNX1T1 DCN ZFPM2 GLI2 LRP1 NAV2

2.93e-061841497e061e85c4bb19f49f6451ddd7a9077d7378ee365
ToppCellPosterior_cortex-Neuronal-Excitatory|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

CACNA1E ARHGAP32 HIVEP2 SPTBN2 PCNX2 RASGRP1 NPAS2

2.93e-06184149725ccf08a8a26d7e7827b6357f33a53aaf423577d
ToppCellAdult-Mesenchymal-matrix_fibroblast_2_cell-D231|Adult / Lineage, Cell type, age group and donor

ADAMTSL1 CTTNBP2 RUNX1T1 DCN ZFPM2 GLI2 SETBP1

3.04e-061851497fb6bd7e849ecf4ed9cd9c4e2a946a2d12d62f804
ToppCellLPS-IL1RA+antiTNF-Epithelial_alveolar-AT_2-Differentiating_AT2|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ARHGAP32 ZNF385B BMP1 PTPN13 NAV2 USP54 PLCH1

3.15e-061861497e83718fabb057100835d3357df407f283d23fe16
ToppCellPCW_07-8.5-Mesenchymal-Mesenchymal_fibroblastic-mes_immature3_(17)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

USP53 GLIS3 RUNX1T1 DCN PTPN13 GLI2 GLI3

3.27e-061871497a9316e2818217ec5feae9cf8816f7249803caee6
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-Adaptive_/_Maladaptive_/_Repairing_Fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ADAMTSL1 RUNX1T1 DCN ZFPM2 GLI2 GLI3 LRP1

3.38e-061881497ce85a56ac27a6432421dde93a1bafa8b943244b9
ToppCellLPS-IL1RA-Epithelial_alveolar-AT_2-Differentiating_AT2|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ARHGAP32 ZNF385B BMP1 PTPN13 NAV2 USP54 PLCH1

3.38e-0618814974bdf8d49af0e9da349b16e3f012e1b0eec04cc4f
ToppCellLPS_only-Stromal_mesenchymal-Matrix_Fibroblast-MatrixFB|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

GLIS3 RUNX1T1 DCN PTPN13 GLI2 SETBP1 LRP1

3.50e-0618914972a22b9fae70afb3dab8476f9c00e48a4df756410
ToppCellTCGA-Cervix-Primary_Tumor-Cervical_Carcinoma-Cervical_Squamous_Cell_Carcinoma-3|TCGA-Cervix / Sample_Type by Project: Shred V9

UBR4 BTAF1 ARHGAP35 MAP3K6 FAT2 LRP1

3.51e-0612214961ed865f0ecfe304fb86313ff51c04e9052357270
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ADAMTSL1 RUNX1T1 DCN ZFPM2 GLI2 GLI3 LRP1

3.63e-0619014972306aa9dbeaef3be8484a5b236605de23cd75d4c
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ADAMTSL1 RUNX1T1 DCN ZFPM2 GLI2 GLI3 LRP1

3.63e-061901497efb757f11c2809e66ddb48a5c84f5433f111cb7c
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ADAMTSL1 RUNX1T1 DCN ZFPM2 GLI2 GLI3 LRP1

3.63e-0619014971f83f7f24288a3b9ab33c2e113e845dba96adc8a
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ADAMTSL1 RUNX1T1 DCN ZFPM2 GLI2 GLI3 LRP1

3.75e-061911497a58c75e9580139fb370b498d95660f10f3a2a27b
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

STARD13 RUNX1T1 DCN GLI2 SETBP1 LRP1 NAV2

3.75e-061911497c54c420a94dc749ebc67fc64c5614663f4b9798d
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

RUNX1T1 DCN ZFPM2 GLI2 GLI3 LRP1 NAV2

3.75e-06191149739092a0aff8097617820c59f5fea9ee2bb4f63a2
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

STARD13 RUNX1T1 DCN GLI2 SETBP1 LRP1 NAV2

3.75e-061911497cb0aee740b08f7d5fdd2717ecf7429043b277ae7
ToppCellEntopeduncular-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)|Entopeduncular / BrainAtlas - Mouse McCarroll V32

MYCBP2 SPTBN2 ZNF385B PCNX2 ELAVL2 ANKRD12 UNC80

3.75e-0619114975d24022cec293bc8d9e978ae99a109e660bb8f83
ToppCellEntopeduncular-Neuronal-Inhibitory|Entopeduncular / BrainAtlas - Mouse McCarroll V32

MYCBP2 SPTBN2 ZNF385B PCNX2 ELAVL2 ANKRD12 UNC80

3.75e-06191149773dae4cdea86aec62393ad7303dc7375a6b3fc86
ToppCellnucseq-Mesenchymal-Fibroblastic-Fibroblastic_2-AF1|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

USP53 RUNX1T1 DCN ZFPM2 GLI2 SETBP1 NAV2

3.75e-0619114976688cee34beee4f151ac17fccbc9c26a9aad72e1
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

RUNX1T1 DCN ZFPM2 GLI2 GLI3 LRP1 NAV2

3.75e-061911497ee5f1b1c59029c46cbb1a00935c03b9317bb9da9
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

RUNX1T1 DCN ZFPM2 GLI2 GLI3 LRP1 NAV2

3.89e-0619214975105e4b577408b4e1a62d0a44c23c2b830ccad88
ToppCellnucseq-Mesenchymal-Fibroblastic-Fibroblastic_2|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

USP53 RUNX1T1 DCN ZFPM2 GLI2 SETBP1 NAV2

3.89e-06192149799ce9e3c4c50cf64ebb62145f2b5420efa0db309
ToppCellChildren_(3_yrs)-Mesenchymal-matrix_fibroblast_2_cell-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

ADAMTSL1 RUNX1T1 DCN ZFPM2 GLI2 GLI3 SETBP1

3.89e-061921497e0f4e4470a71bfa81d9dcd8594e5f82aafc24f81
ToppCellMesenchymal-matrix_fibroblast_2_cell|World / Lineage, Cell type, age group and donor

ADAMTSL1 RUNX1T1 DCN ZFPM2 GLI2 GLI3 SETBP1

3.89e-061921497a769158c49d2b208c4224d85e7ae68c85cc372ed
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ADAMTSL1 RUNX1T1 DCN ZFPM2 GLI2 GLI3 LRP1

4.02e-061931497f1199518c3626fd29bfce65070dd21a660671213
ToppCellChildren_(3_yrs)-Mesenchymal-matrix_fibroblast_2_cell|Children_(3_yrs) / Lineage, Cell type, age group and donor

ADAMTSL1 RUNX1T1 DCN ZFPM2 GLI2 GLI3 SETBP1

4.02e-0619314979ab47b360bee1d4f1092c2269e58acebe9584021
ToppCellFetal_29-31_weeks-Epithelial|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

ADAMTSL1 ZNF385B SHROOM4 PTPN13 NAV2 USP54 PLCH1

4.02e-061931497a0ca3231992f14abcf1a6129573bace320e89d2a
ToppCellChildren_(3_yrs)-Immune-T_lymphocyte-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

HIVEP2 IL18RAP PCNX2 STK10 RASGRP1 KAT2B MYBL1

4.16e-0619414973d6f2d190dd50804afea299957cc44c2bb756134
ToppCellPCW_07-8.5-Mesenchymal-Mesenchymal_fibroblastic|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

GLIS3 RUNX1T1 DCN ZFPM2 GLI2 GLI3 LRP1

4.16e-0619414978c37bedb23285735ff3828db3889897fada8c95d
ToppCellCOVID-19-Fibroblasts-Alveolar_FB|COVID-19 / group, cell type (main and fine annotations)

USP53 CTTNBP2 TTC28 RUNX1T1 DCN SETBP1 NAV2

4.30e-061951497603050beeb33c331d4b2e3fa46cae3f3e0e4bdc7
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

RUNX1T1 DCN ZFPM2 GLI2 SETBP1 LRP1 NAV2

4.30e-0619514973c3703f092b6fc1b7333426fb5e2823bfb74bb57
ToppCellRA-02._Fibroblast_II|RA / Chamber and Cluster_Paper

USP53 GLIS3 DCN ZFPM2 SETBP1 LRP1 NAV2

4.30e-0619514976a02ebbeb3199447ddce64d92d8809436e040eba
ToppCelldroplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TTC28 KIF1A MYCBP2 NAV2 KMT2A UNC80 PHLDB2

4.30e-0619514973e519cffa6144a62b06124642a14c9ff39b76554
ToppCelldroplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TTC28 KIF1A MYCBP2 NAV2 KMT2A UNC80 PHLDB2

4.30e-0619514977796ea9247f4c63762f0de8490fed08b9717fa23
ToppCellPCW_05-06-Mesenchymal|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

TTC28 RUNX1T1 DCN ZFPM2 GLI2 GLI3 SETBP1

4.45e-061961497dca52c57ba35d9395cdbca8b881f12ece721b10f
ToppCellcontrol-immature_Neutrophil|control / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

UBR4 GRN TXNDC11 GGA3 ZCCHC14 SLC24A4 MAML3

4.45e-061961497e34fd3e7a5b1c22a81fd3208e6d58bdb846d51c4
ToppCellnucseq-Mesenchymal-Fibroblastic|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

USP53 RUNX1T1 DCN ZFPM2 GLI2 SETBP1 NAV2

4.45e-0619614977d8505dac15fa59935ccf592afc54b04c4c6554f
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ADAMTSL1 RUNX1T1 DCN ZFPM2 GLI2 GLI3 LRP1

4.60e-0619714976d027119a5f7ca2aac1b10837e43f9a2bb54db85
ToppCellCOVID-19-lung-Fibroblast|COVID-19 / Disease (COVID-19 only), tissue and cell type

RUNX1T1 DCN GLI2 GLI3 SETBP1 LRP1 NAV2

4.76e-0619814973ec01a55ade5e1627258cc3cfebb2c3207a4cb43
ToppCellPCW_10-12-Mesenchymal-Mesenchymal_fibroblastic|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

TTC28 GLIS3 RUNX1T1 DCN ZFPM2 GLI3 LRP1

4.76e-06198149717dc055e2a289496d9c5cdbf3297bdf906dc6d22
ToppCellnucseq-Mesenchymal|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

USP53 RUNX1T1 DCN ZFPM2 GLI2 SETBP1 NAV2

4.76e-0619814978f52243ca8b9ba68a75ae411506a3a6de258eb97
ToppCellFetal_29-31_weeks-Mesenchymal|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

TTC28 RUNX1T1 DCN ZFPM2 GLI2 GLI3 SETBP1

4.76e-06198149721cf4d81386761d09d0f6829c01c198e5524176d
ToppCellMesenchymal|World / Lineage, Cell type, age group and donor

TTC28 RUNX1T1 DCN ZFPM2 GLI2 GLI3 SETBP1

4.92e-0619914974bac110c2b3609f6ee5d0e3275da0824a6240270
ToppCellBronchial-NucSeq-Immune_Lymphocytic-T-T_CD8-CD8_TRM|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

TRAF1 RCSD1 IL18RAP STK10 RASGRP1 INSYN2B MYBL1

5.08e-062001497be9a43acc2f926b9433ab3f018b911b03896a924
ToppCellBronchial-NucSeq-Stromal|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

RUNX1T1 DCN ZFPM2 GLI2 SETBP1 LRP1 PHLDB2

5.08e-062001497389cc775c8419d90fb77cd794376d2160a7bf44e
ToppCellTracheal-NucSeq-Stromal|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

ZNF385B RUNX1T1 DCN ZFPM2 LRP1 NAV2 PHLDB2

5.08e-062001497c318d14bd6fd6f42c597eb55ac9e2f48008aeb9b
ToppCellBronchial-NucSeq-Immune_Lymphocytic-T-T_CD8|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

TRAF1 RCSD1 IL18RAP STK10 RASGRP1 INSYN2B MYBL1

5.08e-06200149702c4169a23e5aaa0d4bfc78b51ba19ce8157dc3e
ToppCellParenchymal-NucSeq-Stromal-Fibroblastic|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

USP53 RUNX1T1 DCN ZFPM2 GLI2 SETBP1 LRP1

5.08e-062001497311fab076f2ceb258e3970eb21e39344b894042a
ToppCellParenchymal-NucSeq-Stromal-Fibroblastic-Fibro_adventitial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

ADAMTSL1 RUNX1T1 DCN ZFPM2 GLI2 SETBP1 LRP1

5.08e-06200149774e74123ea7bf38d337a3a0248a6a51437c6ab42
ToppCellTracheal-NucSeq-Stromal-Fibroblastic-Fibro_adventitial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

ADAMTSL1 RUNX1T1 DCN ZFPM2 LRP1 NAV2 PHLDB2

5.08e-0620014970c25d56292b9e5fefa4521b72635449be1ffd6fe
ToppCellE16.5-samps-Mesenchymal-Matrix_fibroblast-_fetal-matrix_-_immature_3|E16.5-samps / Age Group, Lineage, Cell class and subclass

ZSWIM8 GLIS3 ZBTB26 ZNF318 TRIL SLC37A4

1.11e-051491496651494e84be03dc7b061ebdfa91756a1c507b9b4
ToppCellwk_08-11-Mesenchymal-Fibroblast-Alveolar_fibro|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

SLC24A5 ZIM2 RUNX1T1 DCN LRP1 UNC80

2.05e-05166149665dafed953b01a9830b54309af75c7a561e88336
ToppCellfacs-Diaphragm-Limb_Muscle-24m|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HIVEP2 DCN DNAH1 ELAVL2 PLCH1 UNC80

2.26e-05169149612bdc709bc000d7f9061ecd9fbd57233eaacb7e2
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid-Macrophage_Dendritic-Cycling_Mononuclear_Phagocyte|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CENPF BARD1 CLEC7A RCSD1 MTFR2 MYBL1

2.67e-0517414967b318796728001c17b4043d2b033330c7be40c78
ToppCellfacs-Marrow-Granulocytes-3m-Myeloid-basophil|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SEC16B ADAMTSL1 HTR1B SLC39A4 PFKP IL18RAP

2.75e-0517514961b35acece23712ab7e3f92d9d68266efd38b3ef5
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_4|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SEC16B CENPF RCSD1 PFKP PHLDB2 BAALC

2.75e-05175149606af6629766e2054e6995e8cdb3907658fec49d3
ToppCellfacs-Marrow-Granulocytes-3m-Myeloid-basophil|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SEC16B ADAMTSL1 HTR1B SLC39A4 PFKP IL18RAP

2.75e-051751496a9f88054e2c28d604c65ed785f63021aadb7f4c8
ToppCellsaliva-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_T|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

SEC16B SLC39A4 GRAMD1B DZIP3 KMT2A MYBL1

2.84e-051761496dca70f309af24421f8dc708cbd88512814b8e79e
ToppCellFrontal_cortex-Neuronal-Excitatory-eN1(Slc17a7)-eN1_2-Nptxr-Excitatory_Neuron.Slc17a7.Nptxr-Drd1_(Deep_layer_pyramidal_cells)|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

SYNRG SLC38A9 RIMBP3 ANAPC7 SLC37A4 TGS1

2.84e-0517614963c76a5c4ca2b378667cb155fbb9675519572b35d
ToppCellfacs-Marrow-T-cells-3m-Myeloid-basophil|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SEC16B ADAMTSL1 HTR1B PFKP IL18RAP MAP3K6

3.03e-05178149641745a589567ca5ea6d06331f4c8da03595b5f5c
ToppCellfacs-Marrow-T-cells-3m-Myeloid-basophil|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SEC16B ADAMTSL1 HTR1B PFKP IL18RAP MAP3K6

3.03e-051781496eb940dd64c973f68bcaad6069d3bd56383329db5
ToppCell(05)_Ciliated-(4)_1wkpi|(05)_Ciliated / shred by cell type and Timepoint

SYNRG RCSD1 MUC13 CDK5R1 CAPRIN2 ANAPC7

3.22e-05180149685fc9b164147b28545e2397d32302eea03ef6346
ToppCellLPS-antiTNF-Epithelial_alveolar-AT_2|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ZNF385B BMP1 PTPN13 NAV2 USP54 PLCH1

3.22e-051801496b798a3fa2dd15b68aa4267f665559527043dcc07
ToppCellControl-Epithelial_cells-AT2|Control / group, cell type (main and fine annotations)

GLIS3 ZNF385B BMP1 PTPN13 DMBT1 PLCH1

3.22e-051801496198b19e7910b4a8cc7e820c525ab357c7f99f578
ToppCellChildren_(3_yrs)-Endothelial-endothelial_cell_of_vein-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

JCAD MYRIP RUNX1T1 MAP3K6 ZFPM2 SHROOM4

3.22e-05180149627e8bbee388e64dd79d70b160b76d45b1f398006
ToppCellLPS-antiTNF-Epithelial_alveolar-AT_2-AT2|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SLC39A4 ZNF385B BMP1 PTPN13 USP54 PLCH1

3.43e-0518214961e2149b222a3e9f64841aed45288a6f29394e7b0
ToppCellpdx-Tumor_cells-T6|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)

STARD13 HIVEP2 ZFPM2 SETBP1 NAV2 MAML3

3.43e-0518214967b24a4f712e1ae1525e8f1c8ec4e1fc43489cbee
ToppCellLPS-IL1RA+antiTNF-Epithelial_alveolar-AT_2|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ZNF385B BMP1 PTPN13 NAV2 USP54 PLCH1

3.43e-05182149617ed11a7ea366dd3106400511d5e628d3f1a9c3e
ToppCellAdult-Mesenchymal-matrix_fibroblast_2_cell-D122|Adult / Lineage, Cell type, age group and donor

ADAMTSL1 RUNX1T1 DCN ZFPM2 SETBP1 RAI2

3.65e-0518414962b7e6f91e11c228f0521e099886867d9e998e78d
ToppCellLPS-IL1RA+antiTNF-Epithelial_alveolar-AT_2-AT2_Progenitor|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ZNF385B BMP1 PTPN13 NAV2 USP54 PLCH1

3.65e-051841496d0c212a8fbaad24597a84018442b25c61c17ea58
Drugirinotecan HCl; Down 200; 100uM; PC3; HT_HG-U133A

NRIP1 HIVEP2 GRAMD1B BPTF GLI3 SEC24B NAV2 ANKRD12 KAT6B NPAS2

2.08e-07171150107535_DN
DrugTrichostatin A, from Streptomyces sp.; Down 200; 0.1uM; PC3; HT_HG-U133A

EPHB4 NRIP1 HIVEP2 MAP3K6 BPTF MTMR4 SETBP1 KAT6B NPAS2

2.50e-0617515096316_DN
DrugCamptothecine (S,+) [7689-03-4]; Down 200; 11.4uM; PC3; HT_HG-U133A

NRIP1 SYNRG KAT6A GRAMD1B GLI3 SEC24B NAV2 ANKRD12 KAT6B

3.15e-0618015094541_DN
DrugTestosterone propionate [57-85-2]; Up 200; 11.6uM; MCF7; HT_HG-U133A

KAT6A DCN INO80D PCNX2 BMP1 NAV2 CPLANE1 MUC6 MYBL1

5.56e-0619315095271_UP
DrugDomperidone maleate; Down 200; 7.4uM; MCF7; HT_HG-U133A

HIVEP2 TTC28 ARHGAP35 MAP3K6 INO80D BMP1 CDK5R1 DZIP3 KAT6B

7.13e-0619915095701_DN
DrugCarbinoxamine maleate salt [3505-38-2]; Down 200; 9.8uM; HL60; HT_HG-U133A

EPHB4 HIVEP2 INO80D PITPNM1 PCNX2 ZCCHC14 GPR75 PRR14L TOP3A

7.13e-0619915092725_DN
Diseaseunipolar depression, depressive symptom measurement

CTTNBP2 RASGRP1 KMT2A MAML3

7.69e-06261454EFO_0003761, EFO_0007006
Diseaseserum gamma-glutamyl transferase measurement

JCAD SEC16B ICE2 GLIS3 TNFRSF6B TWNK ARHGAP35 SLCO1B7 TRIL BPTF KAT2B SLC24A4 NAV2 KMT2A YY1AP1 MUC6

1.17e-0591414516EFO_0004532
Diseasewaist-hip ratio

JCAD SEC16B TTC28 MYCBP2 SLC38A9 ZNF318 POU5F1B BPTF KLLN NOTUM GLI3 RNF146 SETBP1 CAPRIN2 MAML3 PHLDB2 NPAS2

1.15e-04122614517EFO_0004343
DiseaseSchizophrenia

NRIP1 ARHGAP32 SPTBN2 GRN CSMD2 PITPNM1 CBLIF CDK5R1 RCBTB1 ERVK-8 LRP1 KMT2A ELAVL2 NPAS2

1.21e-0488314514C0036341
Diseasecortical thickness

CTTNBP2 MYCBP2 SPTBN2 GLIS3 ZNF385B ZNF318 ARHGAP35 RUNX1T1 ZNF106 ZNF469 GLI3 LRP1 NAV2 KMT2A ELAVL2 PLCH1

1.22e-04111314516EFO_0004840
DiseaseExudative retinopathy

CRB1 RCBTB1

1.43e-0441452C0154832
Diseasetestosterone measurement

STARD13 TTC28 ICE2 PABPC4 GLIS3 ZNF385B ZNF318 REXO1 ZFPM2 GGA3 GRAMD1B SHROOM4 KAT2B C2 YY1AP1 TNKS1BP1 SMCR5

1.83e-04127514517EFO_0004908
Diseasedepressive symptom measurement

CACNA1E HTR1B CTTNBP2 GLIS3 VPS54 CRB1 KMT2A ELAVL2 MAML3

2.70e-044261459EFO_0007006
DiseaseHypermetropia, Myopia

NRIP1 ADAMTSL1 GRAMD1B BPTF SLC24A4 PLCH1

3.55e-041891456HP_0000540, HP_0000545
Disease3-hydroxypropylmercapturic acid measurement

JCAD SYNRG TXNDC11 ZFPM2 STK10 KMT2A ELAVL2 NPAS2

3.66e-043521458EFO_0007014
Diseasecognitive function measurement, self reported educational attainment

CACNA1E MYCBP2 BTAF1 RUNX1T1 MTMR4 ELAVL2 MAML3 NPAS2

3.87e-043551458EFO_0004784, EFO_0008354
Diseasepleckstrin homology domain-containing family A member 1 measurement

ZFPM2 DMBT1

4.96e-0471452EFO_0802873
Diseasewellbeing measurement

CACNA1E CTTNBP2 HIVEP2 GLIS3 ZBTB26 VPS54 ZCCHC14 BPTF KMT2A ELAVL2 MAML3

6.46e-0469214511EFO_0007869
DiseaseDisorder of eye

SLC24A5 SPATA7 GRN MFRP CRB1 CPLANE1

6.51e-042121456C0015397
DiseaseCongenital Amaurosis of Retinal Origin

SPATA7 CRB1

6.59e-0481452C3540662
Diseasecoronary aneurysm

CSMD2 SETBP1 NAV2

6.78e-04351453EFO_1000881
Diseaseprimary bacterial infectious disease (implicated_via_orthology)

GLI2 GLI3

8.44e-0491452DOID:0050338 (implicated_via_orthology)
DiseaseMalignant neoplasm of breast

EPHB4 NRIP1 CENPF UBR4 OBSCN BARD1 ZNF318 MAP3K6 GGA3 ZCCHC14 BMP1 SETBP1 USP54 KAT6B

8.62e-04107414514C0006142
Diseasecorpus callosum anterior volume measurement

ADAMTSL1 CTTNBP2 NAV2

9.33e-04391453EFO_0010295
Diseaseintraocular pressure measurement

JCAD CTTNBP2 GLIS3 MFRP DCN ZNF106 ZNF469 KMT2A NPAS2

9.64e-045091459EFO_0004695
DiseaseInherited neuropathies

SPTBN2 TWNK DNAJB2

1.01e-03401453C0598589
DiseaseMicrophthalmos

MFRP CRB1

1.28e-03111452C0026010
Diseaseinterleukin 1 receptor-like 1 measurement

IL18RAP NPAS2

1.28e-03111452EFO_0008168
Diseasecup-to-disc ratio measurement

ADAMTSL1 CTTNBP2 TTC28 ARHGAP35 KAT2B GLI3 NAV2 KMT2A

1.34e-034301458EFO_0006939
Diseasereading and spelling ability

NRIP1 MYRIP PTPN13 SLC24A4 ELAVL2

1.40e-031661455EFO_0005301
DiseaseAdenoid Cystic Carcinoma

KAT6A ZIM2 MAML3 MYBL1

1.52e-031001454C0010606
Diseasecongenital diaphragmatic hernia (implicated_via_orthology)

ZFPM2 LRP1

1.53e-03121452DOID:3827 (implicated_via_orthology)
Diseasegastroesophageal reflux disease

NRIP1 HIVEP2 SKIDA1 MAML3

1.58e-031011454EFO_0003948
DiseaseLeukemia, Myelocytic, Acute

RUNX1T1 RASGRP1 SETBP1 KMT2A BAALC

1.68e-031731455C0023467
Diseasecorneal resistance factor

GLIS3 DCN ZNF106 ZNF469 KAT2B PTPN13 GLI3 KMT2A

1.80e-034511458EFO_0010067
DiseaseAbnormality of refraction

JCAD NRIP1 ARHGAP32 ADAMTSL1 GLIS3 DCN GRAMD1B SLC24A4 RCBTB1 GLI3

1.87e-0367314510HP_0000539
DiseaseSmall cell carcinoma of lung

RUNX1T1 KMT2A ELAVL2

2.40e-03541453C0149925
Diseaseinterleukin 18 receptor 1 measurement

IL18RAP C2

2.41e-03151452EFO_0008178
Diseaseunipolar depression

JCAD CACNA1E ADAMTSL1 CTTNBP2 HIVEP2 ZFPM2 CRB1 ZCCHC14 TRIL BPTF RASGRP1 KRBA1 ELAVL2 MAML3

2.54e-03120614514EFO_0003761
DiseaseC-reactive protein measurement

SEC16B ZSWIM8 PABPC4 TNFRSF6B ZCCHC2 IL18RAP ZFPM2 BPTF ZNF106 ZNF469 RNF146 TNKS1BP1 SNAPC4 MAML3

2.54e-03120614514EFO_0004458
DiseasePolydactyly

CENPF GLI2 GLI3 CPLANE1

2.70e-031171454C0152427
DiseaseLeber congenital amaurosis

SPATA7 CRB1

2.75e-03161452cv:C0339527
DiseaseFEV/FEC ratio

STARD13 JCAD MGAM CTTNBP2 HIVEP2 PABPC4 SKIDA1 GLIS3 RUNX1T1 ZNF106 LRP1 NAV2 DMBT1 PHLDB2

2.99e-03122814514EFO_0004713
DiseaseAcute Myeloid Leukemia, M1

RUNX1T1 RASGRP1 KMT2A BAALC

3.42e-031251454C0026998
DiseaseAcute Myeloid Leukemia (AML-M2)

RUNX1T1 RASGRP1 KMT2A BAALC

3.42e-031251454C1879321
Diseaseischemia (biomarker_via_orthology)

HTR1B MUC13

3.48e-03181452DOID:326 (biomarker_via_orthology)
DiseaseMyeloid Leukemia

SETBP1 KMT2A

3.48e-03181452C0023470
DiseaseLeukemia, Monocytic, Chronic

SETBP1 KMT2A

3.48e-03181452C0023466
Diseasebirth weight

NRIP1 HIVEP2 CENPF ZBTB26 ZFPM2 ZNF469 NOTUM

3.68e-033991457EFO_0004344
DiseaseHereditary Non-Polyposis Colon Cancer Type 2

BARD1 FAN1

3.88e-03191452C1333991
DiseaseColorectal cancer, hereditary nonpolyposis, type 1

BARD1 FAN1

3.88e-03191452C2936783
DiseaseAlzheimer's disease (is_implicated_in)

GRN CDK5R1 LRP1 C2

4.16e-031321454DOID:10652 (is_implicated_in)
Diseasecentral corneal thickness

GLIS3 DCN ZNF106 ZNF469 GLI3 KMT2A

4.34e-033091456EFO_0005213
Diseaseeye colour measurement

SLC24A5 ADAMTSL1 MYCBP2 ZNF469 DMBT1

4.54e-032181455EFO_0009764
DiseaseAntimigraine preparation use measurement

RUNX1T1 LRP1

4.74e-03211452EFO_0009939
Diseasedisease

RASGRP1 SETBP1

4.74e-03211452EFO_0000408
Diseasecognitive function measurement

CACNA1E SEC16B HTR1B TTC28 ZCCHC2 RUNX1T1 ZFPM2 ZCCHC14 GLI3 SETBP1 ELAVL2 C2 MAML3 NPAS2 BAALC

4.75e-03143414515EFO_0008354

Protein segments in the cluster

PeptideGeneStartEntry
PQANLSSAPSQNCSA

HTR1B

21

P28222
GQTQSCPSAQVSPAV

ERVK-18

166

O42043
SGQTQSCPSAQVSPA

ERVK-19

276

O71037
SGQTQSCPSAQVSPA

ERVK-8

276

Q902F8
GQTQSCPSAQVSPAV

ERVK-9

276

Q9UKH3
SCANLSTFAQPPPAQ

CDK5R1

91

Q15078
SFCSQPSVISSPQIN

BARD1

241

Q99728
TATSCNDPGIPQNGS

CSMD2

1381

Q7Z408
CLTESSNSPHPQQSQ

CACNA1E

2206

Q15878
SGNNSVGAIQCPDSQ

GRN

116

P28799
PTENNTSVGPVSNLC

RASGRP1

601

O95267
CSPQTGPAQLETSSE

RCSD1

381

Q6JBY9
SPCLPDSTSLSAGNN

BIVM

91

Q86UB2
CPNSNIPDQESSLQS

ANKRD12

1436

Q6UB98
NTSTPSCQSTNGQPQ

BMP1

91

P13497
SSSVGPAEAQPQTAQ

BPTF

2386

Q12830
TPEQGVQRSCSSQSG

GRAMD1B

56

Q3KR37
APVNGTQTAKNCTDP

SLC24A4

66

Q8NFF2
SNCLGTGDNQSTLVP

RCBTB1

51

Q8NDN9
PQEAPCSSSTIHNNL

RAI2

141

Q9Y5P3
VERPPSSSQQLAQCS

KAT6B

1756

Q8WYB5
ASTSQDASQCQPSPD

NPAS2

651

Q99743
TGNSASTPQSQCLPS

ANAPC7

86

Q9UJX3
QQESGVSPSPQSTCG

MFRP

131

Q9BY79
VGVESNSNGASPEPC

POU5F1B

101

Q06416
APQPGPQNSSCATLS

MUC6

261

Q6W4X9
TDSCQSGGVPTAVQN

PABPC4

491

Q13310
PSLSCQSDAQSPAVT

IL18RAP

176

O95256
PTSCSQNPQPGDSRS

KRBA1

406

A5PL33
SPGGQSSCSSQQSPI

GLI3

706

P10071
ESEPNSPQTQDKGCQ

SMCP

86

P49901
GSASPAVAELCQNTP

NGLY1

11

Q96IV0
PASSPANCAVQSPQT

MAML3

406

Q96JK9
QPCPANSHSNTIGSA

EPHB4

286

P54760
SSLEQPNAGSSSPAC

KAT2B

401

Q92831
SSSLANQQLPPACGA

RUNX1T1

106

Q06455
ESNATCSARTCPPNQ

LRP1

926

Q07954
GLADSAPSCPQNVNI

C2

16

P06681
NSNSVSQASCAPPSQ

ATXN1L

586

P0C7T5
VSGCSTNNLNNPPFT

MGAM

541

O43451
AGQNQPAEPDASACT

JCAD

1106

Q9P266
LNNPCTSTQEPTEGL

ZFPM2

766

Q8WW38
SEQCSALPRPVSTQN

ADAMTSL1

1646

Q8N6G6
ANSTTQSQTFPCPQA

MAP3K6

936

O95382
QSQDHTSTGPACTQP

PCNX2

641

A6NKB5
LSASSCNNLNQPEPS

FAT2

4106

Q9NYQ8
NSIQSNCSVPFTPVD

NXF5

31

Q9H1B4
ATPDTPACVVSLNGN

PFKP

336

Q01813
NNNISVVGSSDFCPP

DCN

301

P07585
NLTAQCPTQPVSSGH

KDM4E

376

B2RXH2
SAFPTCQSNGPVLNT

NRIP1

56

P48552
QTPAAPLDGANVSCS

KREMEN2

341

Q8NCW0
LPDSEGNSQCSNQGT

GGA3

311

Q9NZ52
PSTISGALNQFPQSC

GLI2

1256

P10070
QRNPNPSCAAAETGA

KLLN

101

B2CW77
TQNSEICSGQAPTPD

TWNK

661

Q96RR1
SQCQTPGSTASSEPV

ARHGAP32

841

A7KAX9
SGQTQSCPSAQVSPA

ERVK-7

1036

P63135
VSNVNCVSPSHSPSQ

DZIP3

1096

Q86Y13
SQEESSPCNLQPVNS

GPR75

491

O95800
CNFPESSQNSPTGTP

MTMR4

776

Q9NYA4
DATLSCQIVGNPTPQ

OBSCN

26

Q5VST9
NPSCPTVRDQFTGQE

NOTUM

446

Q6P988
QSSVQPAANCSIKSP

KAT6A

1621

Q92794
CPNSGQASPCASEQS

MLXIP

681

Q9HAP2
QASPCASEQSPSPQS

MLXIP

686

Q9HAP2
PSPQSPQNNCSGKSD

MLXIP

696

Q9HAP2
QDPGSTCPSFNTVRQ

ERVK-10

431

P87889
QDPGSTCPSFNTVRQ

ERVK-19

431

Q9YNA8
QDPGSTCPSFNTVRQ

ERVK-21

431

P62683
QDPGSACPSFNTVRQ

ERVK-24

431

P63145
QDPGSTCPSFNTVRQ

ERVK-6

431

Q7LDI9
QDPGSTCPSFNTVRQ

ERVK-7

431

P63130
QDPGSTCPSFNTVRQ

ERVK-8

431

P62685
QDPGSTCPSFNTVRQ

ERVK-9

431

P63126
VIANESAPPNLCGTS

SLC37A4

351

O43826
PSSGNNSQPCSNPDL

GAK

966

O14976
QDPGSTCPSFNTVRQ

HERVK_113

431

P62684
QGPECSSAPAVQVGT

DNAH1

16

Q9P2D7
GQASVGNQTNTACSP

ICE2

611

Q659A1
QTQSSCSVPSAQEPL

CBLIF

21

P27352
PQTCALAPSEASGAQ

KLF1

91

Q13351
CVTCPVPTQSGQENS

BTAF1

936

O14981
AAQSADVSLNPCNTP

CENPF

131

P49454
TQSPVTFQKGSNAPC

CPLANE1

3071

Q9H799
GQTQSCPSAQVSPAV

ERVK-24

166

P61566
SGQTQSCPSAQVSPA

ERVK-25

276

P61570
SGQTQSCPSAQVSPA

ERVK-6

276

Q69384
GQTQSCPSAQVSPAV

ERVK-7

166

P61567
AATPGLNQPACSDSS

CTTNBP2

641

Q8WZ74
SGGTQVQQTPASCPL

DNAJB2

231

P25686
QQPGLPSQSCSVQSS

CRTC2

506

Q53ET0
PPASQVSTACNQISP

GLIS3

11

Q8NEA6
EDPSTSQGCAQPQGA

FEM1A

256

Q9BSK4
EDTGQSPANSCPQIQ

C19orf67

266

A6NJJ6
TNCETQCPNPQSLSS

BAALC

81

Q8WXS3
NQSFTTASTQTPPQC

CAPRIN2

791

Q6IMN6
GQTQSCPSAQVSPAV

ERVK-21

276

P61565
GQTQSCPSAQVSPAV

ERVK-5

166

Q9HDB8
SNGPTCNNTANGPTT

ELAVL2

6

Q12926
NGPTTINNNCSSPVD

ELAVL2

16

Q12926
TGVPPDTNNETCTAG

EDEM1

291

Q92611
QGSVCKSPQPQNTSL

INO80D

226

Q53TQ3
TDSPGPSQISNAAVQ

KMT2A

3051

Q03164
VTCQESCQPSIGAPS

KRTAP29-1

46

A8MX34
SGQTQSCPSAQVSPA

HERVK_113

276

Q902F9
SNPCQGSATCVNTPG

CRB1

76

P82279
DAGVICSASQSQPTP

DMBT1

1216

Q9UGM3
NNNPTITVADSLSCP

SEC24B

286

O95487
STNNSNPVICPSAGS

SLC38A9

246

Q8NBW4
TCNGGNSEAVPLTSP

MYBL1

421

P10243
SADEVNNNTCSAVPP

KIF1A

956

Q12756
SVGSCSQPALTPNDS

PTPN13

1991

Q12923
ISPPGNQTCGASSNC

PRR14L

716

Q5THK1
NVSGSPQLCSSPDSS

OTP

286

Q5XKR4
ASNSIISCFNNAPPA

FAN1

26

Q9Y2M0
NCNALTTCQDVPSPG

RUSC1

181

Q9BVN2
PASPAQVQSSQDGGC

REXO1

356

Q8N1G1
SDSRSQPGQCCTDNP

STARD13

206

Q9Y3M8
SPASSGASQETPNEC

SYNRG

1006

Q9UMZ2
PSVSDQPGEKENCSQ

RIMBP3

1301

Q9UFD9
SQVAGAPSQCQAGTP

NAV2

211

Q8IVL1
SGACTSQSRPPVQDQ

SLC39A4

306

Q6P5W5
PSLNPLAQSQGLSCT

SKIDA1

746

Q1XH10
NCEFSQPPESSQQGS

SHROOM4

341

Q9ULL8
SAVQNTLCTGPSSQA

SMCR5

36

Q8TEV8
ANESCSNTAPSLTVP

RNF146

21

Q9NTX7
STTGNQPEQGLSACT

MYCBP2

2001

O75592
SQCVNQPEQLVSSAP

NHEJ1

251

Q9H9Q4
NIDPSENSTSNLPNC

SLCO1B7

81

G3V0H7
EINEPCGNSTNLSPS

PHLDB2

836

Q86SQ0
CGNSTNLSPSTQFPA

PHLDB2

841

Q86SQ0
PRAGSPLCNSNLQDS

ARHGAP35

971

Q9NRY4
QDPGSTCPSFNTVRQ

ERVK-9

431

P63128
PVQPLSSPQCNFSSD

ANKHD1

926

Q8IWZ3
QIRTTATQENPSPNC

CLEC7A

206

Q9BXN2
PNCPSSSSTNDFQAN

USP53

996

Q70EK8
QGSSESCTVNIPQQP

ZCCHC2

821

Q9C0B9
TSPQPASAGISQAQA

ZCCHC2

941

Q9C0B9
PEGSQNSLQAAPATT

PITPNM1

641

O00562
GSPGQPCQSSSNDEE

UNC80

156

Q8N2C7
SPINSQSRTCESPNQ

UNC80

246

Q8N2C7
STLNSTGPSNPCQDD

MUC13

166

Q9H3R2
PPSTQAPSVNGVCTD

SPTBN2

2131

O15020
APSVNGVCTDGEPSQ

SPTBN2

2136

O15020
LAPSQSQDSVNEPCS

STK10

366

O94804
SQDSVNEPCSQPSGD

STK10

371

O94804
NEPCSQPSGDRSLQT

STK10

376

O94804
QTPEASQASPCPAVT

TNKS1BP1

321

Q9C0C2
DQQLQNGSCADPSPS

TRIL

406

Q7L0X0
TAASNSCVQVNLPPS

GAFA1

46

Q96PS6
KSNVNQQCPASTPSS

nan

546

Q9UF83
GNSTQCVISPSSEFP

SLC24A5

41

Q71RS6
FQRPQSETNVASGCP

TRAF1

371

Q13077
EISNGLCGLNTSPSQ

SPATA7

551

Q9P0W8
ANPSCSITPITGNNS

ZNF385B

206

Q569K4
TTSNATSNCQENPCP

PLCH1

1066

Q4KWH8
SRNPCKDSPASNSGQ

SEC16B

181

Q96JE7
PPTAAGESNSVTCNC

TOP3A

801

Q13472
PGSNNICDSDNPATE

MTFR2

231

Q6P444
GAGCISQPEQSSPES

ZSCAN4

271

Q8NAM6
TSSCLQGLPDNPDTQ

ZNF469

2786

Q96JG9
APGICTSPQSASQEN

ZIM2

311

Q9NZV7
ASSPQNVANSPTKEC

TXNDC11

801

Q6PKC3
ATCNPNLNPEASSTR

YY1AP1

186

Q9H869
PADSAISGQTSCPNN

ZCCHC14

646

Q8WYQ9
SQSTAINTVCGAPDP

ZSWIM8

261

A7E2V4
SPGCDSQTSQLDQPL

TTC28

2271

Q96AY4
VSCPESGLGQSQAPA

SNAPC4

1016

Q5SXM2
SQTECTSSNGQNPSP

TOGARAM1

796

Q9Y4F4
NNPEPEKCQSVSSAG

TGS1

566

Q96RS0
SSCNPNPSGLNTKTT

HIVEP2

1676

P31629
PSASVSNICPSNLNQ

UBR4

2441

Q5T4S7
SDSGPVTQNCFISPE

SETBP1

226

Q9Y6X0
ENSVSPIGCNSSDPA

ZNF318

2046

Q5VUA4
NVNAVPPSSACNVSK

ZNF106

1211

Q9H2Y7
TDSKGCQPQPDATQV

ZBTB26

406

Q9HCK0
SQRNASPNSEPCSSD

VPS54

536

Q9P1Q0
AGVIAPGTPSQNTQC

TNFRSF6B

136

O95407
QPSACLPTQAGTLSQ

USP54

876

Q70EL1
APGCQEQTANNPTES

INSYN2B

351

A6NMK8
TQAQSSDQGPIAASP

MYRIP

426

Q8NFW9