Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	G protein-coupled receptor kinase activity	GRK4 GRK5 GRK6	1.06e-05	7	136	3	GO:0004703
GeneOntologyMolecularFunction	Roundabout binding	RTN4R SLIT2 SLIT3	6.50e-05	12	136	3	GO:0048495
GeneOntologyMolecularFunction	protein kinase A catalytic subunit binding	RYR2 PRKAR1A PRKAR1B	1.62e-04	16	136	3	GO:0034236
GeneOntologyMolecularFunction	ryanodine-sensitive calcium-release channel activity	RYR1 RYR2	2.74e-04	4	136	2	GO:0005219
GeneOntologyMolecularFunction	beta-adrenergic receptor kinase activity	GRK5 GRK6	2.74e-04	4	136	2	GO:0047696
GeneOntologyMolecularFunction	all-trans retinal binding	ABCA4 OPN3	4.54e-04	5	136	2	GO:0005503
GeneOntologyMolecularFunction	protein kinase A binding	MYRIP RYR2 PRKAR1A PRKAR1B	6.57e-04	58	136	4	GO:0051018
GeneOntologyMolecularFunction	calcium-induced calcium release activity	RYR1 RYR2	6.78e-04	6	136	2	GO:0048763
GeneOntologyMolecularFunction	11-cis retinal binding	ABCA4 OPN3	9.46e-04	7	136	2	GO:0005502
GeneOntologyMolecularFunction	protein serine/threonine kinase activity	DCAF1 GRK4 GRK5 RPS6KB1 GRK6 PDPK2P MAST2 MARK4 EIF2AK1 PKN3	9.72e-04	446	136	10	GO:0004674
GeneOntologyCellularComponent	smooth endoplasmic reticulum	APOB FTCD RYR1 RYR2 SLMAP	1.29e-05	46	138	5	GO:0005790
Domain	AGC-kinase_C	GRK4 GRK5 RPS6KB1 GRK6 MAST2 PKN3	2.70e-06	56	132	6	IPR000961
Domain	AGC_KINASE_CTER	GRK4 GRK5 RPS6KB1 GRK6 MAST2 PKN3	2.70e-06	56	132	6	PS51285
Domain	S_TK_X	GRK4 GRK5 RPS6KB1 GRK6 MAST2 PKN3	2.70e-06	56	132	6	SM00133
Domain	GPCR_kinase	GRK4 GRK5 GRK6	1.18e-05	7	132	3	IPR000239
Domain	DUF4062	TEP1 NWD2	4.96e-05	2	132	2	PF13271
Domain	DUF4062	TEP1 NWD2	4.96e-05	2	132	2	IPR025139
Domain	Ryanodine_rcpt	RYR1 RYR2	1.48e-04	3	132	2	IPR003032
Domain	Ryanrecept_TM4-6	RYR1 RYR2	1.48e-04	3	132	2	IPR009460
Domain	RyR	RYR1 RYR2	1.48e-04	3	132	2	PF02026
Domain	RR_TM4-6	RYR1 RYR2	1.48e-04	3	132	2	PF06459
Domain	Ryan_recept	RYR1 RYR2	1.48e-04	3	132	2	IPR013333
Domain	CTCK_1	SOST SLIT2 SLIT3	2.61e-04	18	132	3	PS01185
Domain	cAMP_dep_PK_reg_su	PRKAR1A PRKAR1B	2.95e-04	4	132	2	IPR012198
Domain	CT	SOST SLIT2 SLIT3	4.82e-04	22	132	3	SM00041
Domain	Cys_knot_C	SOST SLIT2 SLIT3	7.08e-04	25	132	3	IPR006207
Domain	CTCK_2	SOST SLIT2 SLIT3	7.08e-04	25	132	3	PS01225
Domain	RIH_assoc-dom	RYR1 RYR2	7.30e-04	6	132	2	IPR013662
Domain	Ins145_P3_rec	RYR1 RYR2	7.30e-04	6	132	2	PF08709
Domain	RIIa	PRKAR1A PRKAR1B	7.30e-04	6	132	2	SM00394
Domain	RIH_assoc	RYR1 RYR2	7.30e-04	6	132	2	PF08454
Domain	RIH_dom	RYR1 RYR2	7.30e-04	6	132	2	IPR000699
Domain	Ins145_P3_rcpt	RYR1 RYR2	7.30e-04	6	132	2	IPR014821
Domain	Ryanodine_recept-rel	RYR1 RYR2	7.30e-04	6	132	2	IPR015925
Domain	-	RYR1 RYR2	7.30e-04	6	132	2	1.25.10.30
Domain	RYDR_ITPR	RYR1 RYR2	7.30e-04	6	132	2	PF01365
Domain	Ser/Thr_kinase_AS	WEE1 GRK4 GRK5 RPS6KB1 GRK6 MAST2 MARK4 EIF2AK1 PKN3	9.94e-04	357	132	9	IPR008271
Domain	RIIa	PRKAR1A PRKAR1B	1.02e-03	7	132	2	PF02197
Domain	TSP_1	ADAMTS19 CILP ADAMTS13 SEMA5B	1.03e-03	63	132	4	PF00090
Domain	S_TKc	WEE1 GRK4 GRK5 RPS6KB1 GRK6 MAST2 MARK4 EIF2AK1 PKN3	1.03e-03	359	132	9	SM00220
Domain	PROTEIN_KINASE_ST	WEE1 GRK4 GRK5 RPS6KB1 GRK6 MAST2 MARK4 EIF2AK1 PKN3	1.10e-03	362	132	9	PS00108
Domain	TSP1	ADAMTS19 CILP ADAMTS13 SEMA5B	1.16e-03	65	132	4	SM00209
Domain	TSP1_rpt	ADAMTS19 CILP ADAMTS13 SEMA5B	1.16e-03	65	132	4	IPR000884
Domain	TSP1	ADAMTS19 CILP ADAMTS13 SEMA5B	1.16e-03	65	132	4	PS50092
Domain	LRR_8	LRRC8C VASN RTN4R LRRC10B SLIT2 SLIT3	1.37e-03	171	132	6	PF13855
Domain	LRRCT	VASN SLIT2 SLIT3	1.47e-03	32	132	3	PF01463
Domain	Pkinase	WEE1 GRK4 GRK5 RPS6KB1 GRK6 MAST2 MARK4 EIF2AK1 PKN3	1.56e-03	381	132	9	PF00069
Domain	LRR_TYP	LRRC8C VASN RTN4R LRRC10B SLIT2 SLIT3	1.63e-03	177	132	6	SM00369
Domain	Leu-rich_rpt_typical-subtyp	LRRC8C VASN RTN4R LRRC10B SLIT2 SLIT3	1.63e-03	177	132	6	IPR003591
Domain	RGS	GRK4 GRK5 GRK6	1.91e-03	35	132	3	PF00615
Domain	RGS	GRK4 GRK5 GRK6	1.91e-03	35	132	3	SM00315
Domain	EGF	VASN LRP1B SLIT2 SLIT3 FBN3	2.02e-03	126	132	5	PF00008
Domain	RGS	GRK4 GRK5 GRK6	2.08e-03	36	132	3	PS50132
Domain	MIR	RYR1 RYR2	2.15e-03	10	132	2	PF02815
Domain	MIR_motif	RYR1 RYR2	2.15e-03	10	132	2	IPR016093
Domain	MIR	RYR1 RYR2	2.15e-03	10	132	2	PS50919
Domain	MIR	RYR1 RYR2	2.15e-03	10	132	2	SM00472
Domain	RGS	GRK4 GRK5 GRK6	2.62e-03	39	132	3	IPR016137
Domain	LRR	LRRC8C VASN RTN4R LRRC10B SLIT2 SLIT3	3.07e-03	201	132	6	PS51450
Domain	Leu-rich_rpt	LRRC8C VASN CARMIL1 RTN4R LRRC10B SLIT2 SLIT3	3.17e-03	271	132	7	IPR001611
Domain	Pkinase_C	RPS6KB1 MAST2 PKN3	3.24e-03	42	132	3	PF00433
Domain	Cys-rich_flank_reg_C	VASN RTN4R SLIT2 SLIT3	3.81e-03	90	132	4	IPR000483
Domain	LRRCT	VASN RTN4R SLIT2 SLIT3	3.81e-03	90	132	4	SM00082
Domain	ConA-like_dom	TRIM41 RYR1 RYR2 SLIT2 COL21A1 SLIT3	4.67e-03	219	132	6	IPR013320
Domain	LRR_1	LRRC8C VASN RTN4R LRRC10B SLIT2 SLIT3	4.67e-03	219	132	6	PF00560
Domain	cAMP_dep_PK_reg_su_I/II_a/b	PRKAR1A PRKAR1B	4.90e-03	15	132	2	IPR003117
Domain	EGF_Ca-bd_CS	LRP1B SLIT2 SLIT3 FBN3	4.98e-03	97	132	4	IPR018097
Domain	LRRNT	VASN RTN4R SLIT2 SLIT3	5.16e-03	98	132	4	IPR000372
Domain	LRRNT	VASN RTN4R SLIT2 SLIT3	5.16e-03	98	132	4	SM00013
Domain	Kinase-like_dom	WEE1 GRK4 GRK5 RPS6KB1 GRK6 MAST2 TRRAP MARK4 EIF2AK1 PKN3	5.17e-03	542	132	10	IPR011009
Domain	EGF_CA	LRP1B SLIT2 SLIT3 FBN3	5.35e-03	99	132	4	PS01187
Domain	PROTEIN_KINASE_ATP	WEE1 GRK4 GRK5 RPS6KB1 GRK6 MAST2 MARK4 EIF2AK1 PKN3	5.36e-03	459	132	9	PS00107
Domain	Protein_kinase_ATP_BS	WEE1 GRK4 GRK5 RPS6KB1 GRK6 MARK4 EIF2AK1 PKN3	5.56e-03	379	132	8	IPR017441
Domain	cNMP-bd_CS	PRKAR1A PRKAR1B	5.58e-03	16	132	2	IPR018488
Domain	LRRNT	VASN SLIT2 SLIT3	6.25e-03	53	132	3	PF01462
Domain	EGF-type_Asp/Asn_hydroxyl_site	LRP1B SLIT2 SLIT3 FBN3	6.80e-03	106	132	4	IPR000152
Pathway	WP_MYOMETRIAL_RELAXATION_AND_CONTRACTION_PATHWAYS	GRK4 GRK5 GRK6 GPR182 RYR1 RYR2 PRKAR1A PRKAR1B CORIN NOS3	9.11e-08	154	96	10	MM15974
Pathway	WP_MYOMETRIAL_RELAXATION_AND_CONTRACTION_PATHWAYS	GRK4 GRK5 GRK6 GPR182 RYR1 RYR2 PRKAR1A PRKAR1B CORIN NOS3	1.03e-07	156	96	10	M39475
Pathway	BIOCARTA_AGPCR_PATHWAY	GRK4 PRKAR1A PRKAR1B	3.55e-05	10	96	3	MM1352
Pathway	BIOCARTA_NO1_PATHWAY	RYR2 PRKAR1A PRKAR1B NOS3	3.65e-05	28	96	4	M4383
Pathway	BIOCARTA_AGPCR_PATHWAY	GRK4 PRKAR1A PRKAR1B	4.85e-05	11	96	3	M19829
Pathway	WP_CALCIUM_REGULATION_IN_CARDIAC_CELLS	GRK4 GRK5 GRK6 RYR1 RYR2 PRKAR1A PRKAR1B	6.38e-05	147	96	7	MM15854
Pathway	WP_CALCIUM_REGULATION_IN_CARDIAC_CELLS	GRK4 GRK5 GRK6 RYR1 RYR2 PRKAR1A PRKAR1B	7.56e-05	151	96	7	M39329
Pathway	REACTOME_FACTORS_INVOLVED_IN_MEGAKARYOCYTE_DEVELOPMENT_AND_PLATELET_PRODUCTION	CARMIL1 EHHADH PRKAR1A PRKAR1B KIF2A KIF18B	1.38e-04	116	96	6	MM15715
Pubmed	The GRK4 subfamily of G protein-coupled receptor kinases. Alternative splicing, gene organization, and sequence conservation.	GRK4 GRK5 GRK6	1.24e-06	6	139	3	10506199
Pubmed	Members of the G protein-coupled receptor kinase family that phosphorylate the beta2-adrenergic receptor facilitate sequestration.	GRK4 GRK5 GRK6	2.16e-06	7	139	3	8672451
Pubmed	Determination of bradykinin B2 receptor in vivo phosphorylation sites and their role in receptor function.	GRK4 GRK5 GRK6	2.16e-06	7	139	3	11517230
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	LZTR1 GRK5 GRK6 RDH10 SPPL2B TEP1 MAST2 TRRAP RYR1 FZD7 HIVEP3 ARAP3 CSAD MARK4 ZFYVE26 PKN3 RAI1	2.18e-06	1105	139	17	35748872
Pubmed	Promoter for the regulatory type I beta subunit of the 3',5'-cyclic adenosine monophosphate-dependent protein kinase directs transgene expression in the central nervous system.	PRKAR1A PRKAR1B	1.59e-05	2	139	2	1448119
Pubmed	Skeletal and cardiac ryanodine receptors exhibit different responses to Ca2+ overload and luminal ca2+.	RYR1 RYR2	1.59e-05	2	139	2	17259277
Pubmed	Ryanodine receptor oligomeric interaction: identification of a putative binding region.	RYR1 RYR2	1.59e-05	2	139	2	14722100
Pubmed	Structural and functional interactions within ryanodine receptor.	RYR1 RYR2	1.59e-05	2	139	2	26009179
Pubmed	Structure and Function of the Human Ryanodine Receptors and Their Association with Myopathies-Present State, Challenges, and Perspectives.	RYR1 RYR2	1.59e-05	2	139	2	32899693
Pubmed	Inhibitory effects of two G protein-coupled receptor kinases on the cell surface expression and signaling of the human adrenomedullin receptor.	GRK4 GRK5	1.59e-05	2	139	2	26820533
Pubmed	Soluble Frizzled-7 receptor inhibits Wnt signaling and sensitizes hepatocellular carcinoma cells towards doxorubicin.	WNT3 FZD7	1.59e-05	2	139	2	21314951
Pubmed	Ryanodine receptors in human pancreatic beta cells: localization and effects on insulin secretion.	RYR1 RYR2	1.59e-05	2	139	2	15033925
Pubmed	Beta-arrestin-mediated beta1-adrenergic receptor transactivation of the EGFR confers cardioprotection.	GRK5 GRK6	1.59e-05	2	139	2	17786238
Pubmed	Role for the regulator of G-protein signaling homology domain of G protein-coupled receptor kinases 5 and 6 in beta 2-adrenergic receptor and rhodopsin phosphorylation.	GRK5 GRK6	1.59e-05	2	139	2	20038610
Pubmed	Functional interaction between Wnt3 and Frizzled-7 leads to activation of the Wnt/beta-catenin signaling pathway in hepatocellular carcinoma cells.	WNT3 FZD7	1.59e-05	2	139	2	18313787
Pubmed	Recent advances in understanding the ryanodine receptor calcium release channels and their role in calcium signalling.	RYR1 RYR2	1.59e-05	2	139	2	30542613
Pubmed	Ryanodine receptors are expressed and functionally active in mouse spermatogenic cells and their inhibition interferes with spermatogonial differentiation.	RYR1 RYR2	1.59e-05	2	139	2	15280431
Pubmed	Expression of the ryanodine receptor isoforms in immune cells.	RYR1 RYR2	1.59e-05	2	139	2	11673493
Pubmed	B-lymphocytes from malignant hyperthermia-susceptible patients have an increased sensitivity to skeletal muscle ryanodine receptor activators.	RYR1 RYR2	1.59e-05	2	139	2	11673462
Pubmed	Crystal structures of wild type and disease mutant forms of the ryanodine receptor SPRY2 domain.	RYR1 RYR2	1.59e-05	2	139	2	25370123
Pubmed	Novel isozymes of cAMP-dependent protein kinase exist in human cells due to formation of RI alpha-RI beta heterodimeric complexes.	PRKAR1A PRKAR1B	1.59e-05	2	139	2	8407966
Pubmed	Thermodynamics of calmodulin binding to cardiac and skeletal muscle ryanodine receptor ion channels.	RYR1 RYR2	1.59e-05	2	139	2	18618700
Pubmed	Spatially heterogeneous choroid plexus transcriptomes encode positional identity and contribute to regional CSF production.	CDH26 ABCA4 RDH10 SLIT3	2.21e-05	41	139	4	25810521
Pubmed	Possible roles of Robo1+ ensheathing cells in guiding dorsal-zone olfactory sensory neurons in mouse.	SLIT2 ACSM4 SLIT3	2.74e-05	15	139	3	23821580
Pubmed	SHLD2/FAM35A co-operates with REV7 to coordinate DNA double-strand break repair pathway choice.	TRRAP GTF3C1 DNAJC11 KIF2A KIF18B RAI1	3.26e-05	150	139	6	30154076
Pubmed	Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.	DPF1 DCAF1 LZTR1 WEE1 GPATCH2 TEP1 MAST2 TRRAP SLIT2 TRMT2A UBR5 MARK4 KIF18B RAI1 KNL1	4.29e-05	1116	139	15	31753913
Pubmed	Chromosomal mapping of the genes GPRK5 and GPRK6 encoding G protein-coupled receptor kinases GRK5 and GRK6.	GRK5 GRK6	4.75e-05	3	139	2	7789183
Pubmed	Type 1 and type 3 ryanodine receptors are selectively involved in muscarinic antinociception in mice: an antisense study.	RYR1 RYR2	4.75e-05	3	139	2	18403125
Pubmed	G Protein-coupled receptor kinases phosphorylate LRP6 in the Wnt pathway.	GRK5 GRK6	4.75e-05	3	139	2	19801552
Pubmed	Vertebrate slit, a secreted ligand for the transmembrane protein roundabout, is a repellent for olfactory bulb axons.	SLIT2 SLIT3	4.75e-05	3	139	2	10102269
Pubmed	Increased renal oxidative stress in salt-sensitive human GRK4γ486V transgenic mice.	GRK4 NOS3	4.75e-05	3	139	2	28189851
Pubmed	Cloning and expressions of three mammalian homologues of Drosophila slit suggest possible roles for Slit in the formation and maintenance of the nervous system.	SLIT2 SLIT3	4.75e-05	3	139	2	9813312
Pubmed	Function of Slit/Robo signaling in breast cancer.	SLIT2 SLIT3	4.75e-05	3	139	2	26542734
Pubmed	The ryanodine receptor/calcium channel genes are widely and differentially expressed in murine brain and peripheral tissues.	RYR1 RYR2	4.75e-05	3	139	2	7876312
Pubmed	Dendritic differentiation of cerebellar Purkinje cells is promoted by ryanodine receptors expressed by Purkinje and granule cells.	RYR1 RYR2	4.75e-05	3	139	2	24123915
Pubmed	Deficient ryanodine receptor S-nitrosylation increases sarcoplasmic reticulum calcium leak and arrhythmogenesis in cardiomyocytes.	RYR2 NOS3	4.75e-05	3	139	2	18077344
Pubmed	Axonal growth regulation of fetal and embryonic stem cell-derived dopaminergic neurons by Netrin-1 and Slits.	SLIT2 SLIT3	4.75e-05	3	139	2	16840550
Pubmed	G protein-coupled receptor kinase GRK4. Molecular analysis of the four isoforms and ultrastructural localization in spermatozoa and germinal cells.	GRK4 GRK5	4.75e-05	3	139	2	9092566
Pubmed	Dopamine D1 receptor signaling system regulates ryanodine receptor expression in ethanol physical dependence.	RYR1 RYR2	4.75e-05	3	139	2	23278119
Pubmed	miR-16 and miR-26a target checkpoint kinases Wee1 and Chk1 in response to p53 activation by genotoxic stress.	WEE1 GDE1	4.75e-05	3	139	2	24336073
Pubmed	Bidirectional coupling between ryanodine receptors and Ca2+ release-activated Ca2+ (CRAC) channel machinery sustains store-operated Ca2+ entry in human T lymphocytes.	RYR1 RYR2	4.75e-05	3	139	2	22948152
Pubmed	Developmental changes in expression of the three ryanodine receptor mRNAs in the mouse brain.	RYR1 RYR2	4.75e-05	3	139	2	10788707
Pubmed	GRK5 Gln41Leu polymorphism is not associated with sensitivity to beta(1)-adrenergic blockade in humans.	GRK4 GRK5	4.75e-05	3	139	2	19842931
Pubmed	Ca(2+)-induced Ca2+ release in myocytes from dyspedic mice lacking the type-1 ryanodine receptor.	RYR1 RYR2	4.75e-05	3	139	2	7621815
Pubmed	Exclusion of catalytic and regulatory subunits of cAMP-dependent protein kinase as candidate genes for the defect causing cystic fibrosis.	PRKAR1A PRKAR1B	4.75e-05	3	139	2	3479018
Pubmed	Granulocyte chemotaxis and disease expression are differentially regulated by GRK subtype in an acute inflammatory arthritis model (K/BxN).	GRK5 GRK6	4.75e-05	3	139	2	18662895
Pubmed	Molecular identification of the ryanodine receptor pore-forming segment.	RYR1 RYR2	4.75e-05	3	139	2	10473538
Pubmed	Intraislet SLIT-ROBO signaling is required for beta-cell survival and potentiates insulin secretion.	SLIT2 SLIT3	4.75e-05	3	139	2	24065825
Pubmed	Slit-mediated repulsion is a key regulator of motor axon pathfinding in the hindbrain.	SLIT2 SLIT3	4.75e-05	3	139	2	16162649
Pubmed	Mapping of the Prkar1a gene to mouse chromosome 11.	WNT3 PRKAR1A	4.75e-05	3	139	2	8662216
Pubmed	Lifestyle and socioeconomic-status modify the effects of ADRB2 and NOS3 on adiposity in European-American and African-American adolescents.	APOB NOS3	4.75e-05	3	139	2	20930716
Pubmed	Concurrent Wnt pathway component expression in breast and colorectal cancer.	WNT3 FZD7	4.75e-05	3	139	2	32534708
Pubmed	Heterogeneous gene expression and functional activity of ryanodine receptors in resistance and conduit pulmonary as well as mesenteric artery smooth muscle cells.	RYR1 RYR2	4.75e-05	3	139	2	18434746
Pubmed	Serum Glycoprotein Biomarker Discovery and Qualification Pipeline Reveals Novel Diagnostic Biomarker Candidates for Esophageal Adenocarcinoma.	APOB GSN	4.75e-05	3	139	2	26404905
Pubmed	Defective lymphocyte chemotaxis in beta-arrestin2- and GRK6-deficient mice.	GRK5 GRK6	4.75e-05	3	139	2	12032308
Pubmed	SPRY domains in ryanodine receptors (Ca(2+)-release channels).	RYR1 RYR2	4.75e-05	3	139	2	9204703
Pubmed	Distinct but overlapping expression patterns of two vertebrate slit homologs implies functional roles in CNS development and organogenesis.	SLIT2 SLIT3	4.75e-05	3	139	2	10349621
Pubmed	Ryanodine receptors are expressed in epidermal keratinocytes and associated with keratinocyte differentiation and epidermal permeability barrier homeostasis.	RYR1 RYR2	4.75e-05	3	139	2	21881589
Pubmed	Conserved modularity and potential for alternate splicing in mouse and human Slit genes.	SLIT2 SLIT3	4.75e-05	3	139	2	12141424
Pubmed	Isoform-dependent formation of heteromeric Ca2+ release channels (ryanodine receptors).	RYR1 RYR2	4.75e-05	3	139	2	12213830
Pubmed	A kinase anchoring protein (AKAP) interaction and dimerization of the RIalpha and RIbeta regulatory subunits of protein kinase a in vivo by the yeast two hybrid system.	PRKAR1A PRKAR1B	4.75e-05	3	139	2	12634056
Pubmed	Expression of the ryanodine receptor type 3 calcium release channel during development and differentiation of mammalian skeletal muscle cells.	RYR1 RYR2	4.75e-05	3	139	2	9242641
Pubmed	Direct association of the reticulon protein RTN1A with the ryanodine receptor 2 in neurons.	RYR1 RYR2	4.75e-05	3	139	2	23454728
Pubmed	Expression of G-protein-coupled receptor kinases in pregnant term and non-pregnant human myometrium.	GRK5 GRK6	4.75e-05	3	139	2	10467231
Pubmed	Calcineurin upregulates local Ca(2+) signaling through ryanodine receptor-1 in airway smooth muscle cells.	RYR1 RYR2	4.75e-05	3	139	2	25239916
Pubmed	The p38-interacting protein (p38IP) regulates G2/M progression by promoting α-tubulin acetylation via inhibiting ubiquitination-induced degradation of the acetyltransferase GCN5.	SUPT20HL1 SUPT20HL2	4.75e-05	3	139	2	24220028
Pubmed	A gene-specific cerebral types 1, 2, and 3 RyR protein knockdown induces an antidepressant-like effect in mice.	RYR1 RYR2	4.75e-05	3	139	2	18643873
Pubmed	Identification of mutations in the cardiac ryanodine receptor gene in families affected with arrhythmogenic right ventricular cardiomyopathy type 2 (ARVD2).	RYR1 RYR2	4.75e-05	3	139	2	11159936
Pubmed	Intracellular calcium release channel expression during embryogenesis.	RYR1 RYR2	4.75e-05	3	139	2	9986730
Pubmed	Chromosomal localization of murine ryanodine receptor genes RYR1, RYR2, and RYR3 by in situ hybridization.	RYR1 RYR2	4.75e-05	3	139	2	7959768
Pubmed	The organization of proteins in the human red blood cell membrane. A review.	RYR1 RYR2	4.75e-05	3	139	2	4600883
Pubmed	Regulation of mouse egg activation: presence of ryanodine receptors and effects of microinjected ryanodine and cyclic ADP ribose on uninseminated and inseminated eggs.	RYR1 RYR2	4.75e-05	3	139	2	7635066
Pubmed	Myotubularin-related proteins 3 and 4 interact with polo-like kinase 1 and centrosomal protein of 55 kDa to ensure proper abscission.	DCAF1 PMS2 WEE1 UBR5 PRKAR1A KIF2A	5.94e-05	167	139	6	25659891
Pubmed	Prediction of the coding sequences of unidentified human genes. XX. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.	KBTBD8 SANBR MARK4 FBN3 RAI1	7.27e-05	107	139	5	11347906
Pubmed	ACMG recommendations for reporting of incidental findings in clinical exome and genome sequencing.	PMS2 APOB RYR1 RYR2	8.19e-05	57	139	4	23788249
Pubmed	Expression and roles of Slit/Robo in human ovarian cancer.	SLIT2 SLIT3	9.47e-05	4	139	2	21465248
Pubmed	G-protein receptor kinases 2, 5 and 6 redundantly modulate Smoothened-GATA transcriptional crosstalk in fetal mouse hearts.	GRK5 GRK6	9.47e-05	4	139	2	29969579
Pubmed	Slits contribute to the guidance of retinal ganglion cell axons in the mammalian optic tract.	SLIT2 SLIT3	9.47e-05	4	139	2	16828733
Pubmed	Cyclic nucleotide mapping of hyperpolarization-activated cyclic nucleotide-gated (HCN) channels.	PRKAR1A PRKAR1B	9.47e-05	4	139	2	24605759
Pubmed	Calmodulin modulates the termination threshold for cardiac ryanodine receptor-mediated Ca2+ release.	RYR1 RYR2	9.47e-05	4	139	2	23992453
Pubmed	Ryanodine receptor calcium release channels: lessons from structure-function studies.	RYR1 RYR2	9.47e-05	4	139	2	23413940
Pubmed	Role of G protein-coupled receptor kinases on the agonist-induced phosphorylation and internalization of the follitropin receptor.	GRK4 GRK6	9.47e-05	4	139	2	10379886
Pubmed	Extrinsic Regulators of mRNA Translation in Developing Brain: Story of WNTs.	WNT3 FZD7	9.47e-05	4	139	2	33525513
Pubmed	Partial cloning and differential expression of ryanodine receptor/calcium-release channel genes in human tissues including the hippocampus and cerebellum.	RYR1 RYR2	9.47e-05	4	139	2	9607712
Pubmed	Targeting skeletal endothelium to ameliorate bone loss.	HIVEP3 SLIT3	9.47e-05	4	139	2	29785024
Pubmed	ADAMTS-3, -13, -16, and -19 levels in patients with habitual abortion.	ADAMTS19 ADAMTS13	9.47e-05	4	139	2	28088271
Pubmed	Hypoxia differently modulates gene expression of inositol 1,4,5-trisphosphate receptors in mouse kidney and HEK 293 cell line.	RYR1 RYR2	9.47e-05	4	139	2	19120137
Pubmed	FKBP binding characteristics of cardiac microsomes from diverse vertebrates.	RYR1 RYR2	9.47e-05	4	139	2	11237759
Pubmed	The Ca2+ channel alpha2delta-1 subunit determines Ca2+ current kinetics in skeletal muscle but not targeting of alpha1S or excitation-contraction coupling.	CACNA2D1 RYR1	9.47e-05	4	139	2	15536090
Pubmed	Conserved and divergent functions of Nfix in skeletal muscle development during vertebrate evolution.	RYR1 RYR2	9.47e-05	4	139	2	23482488
Pubmed	A glutathione deficit alters dopamine modulation of L-type calcium channels via D2 and ryanodine receptors in neurons.	RYR1 RYR2	9.47e-05	4	139	2	18206662
Pubmed	Alpha/beta-tubulin are A kinase anchor proteins for type I PKA in neurons.	PRKAR1A PRKAR1B	9.47e-05	4	139	2	19056362
Pubmed	Increase of ryanodine receptors by dopamine D1 receptors is negatively regulated by γ-aminobutyric acid type B receptors in primary cultures of mouse cerebral cortical neurons.	RYR1 RYR2	9.47e-05	4	139	2	22504960
Pubmed	Reduced expression of G protein-coupled receptor kinases in schizophrenia but not in schizoaffective disorder.	GRK5 GRK6	9.47e-05	4	139	2	21784156
Pubmed	SLIT/ROBO1 signaling suppresses mammary branching morphogenesis by limiting basal cell number.	SLIT2 SLIT3	9.47e-05	4	139	2	21664580
Pubmed	Novel regulated expression of the SLIT/ROBO pathway in the ovary: possible role during luteolysis in women.	SLIT2 SLIT3	9.47e-05	4	139	2	18566128
Pubmed	Phosphorylation and desensitization of the human thromboxane receptor-alpha by G protein-coupled receptor kinases.	GRK5 GRK6	9.47e-05	4	139	2	11504827
Pubmed	Localization and quaternary structure of the PKA RIβ holoenzyme.	PRKAR1A PRKAR1B	9.47e-05	4	139	2	22797896
Pubmed	Requirement for the ryanodine receptor type 3 for efficient contraction in neonatal skeletal muscles.	RYR1 RYR2	9.47e-05	4	139	2	9384575
Pubmed	Muscarinic-dependent phosphorylation of the cardiac ryanodine receptor by protein kinase G is mediated by PI3K-AKT-nNOS signaling.	RYR2 NOS3	9.47e-05	4	139	2	32580946
GeneFamily	Ryanodine receptors\|Protein phosphatase 1 regulatory subunits	RYR1 RYR2	5.93e-05	3	81	2	287
ToppCell	facs-Trachea-18m-Endothelial-endothelial_cell_of_trachea-tracheal_endothelial_cell-tracheal_endothelial_cell_l54\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ABCA4 GPR182 CBFA2T3 N4BP3 RNF215 ARAP3 CCL21 NOS3 PKN3	7.15e-09	185	139	9	59acaf025353405948dc34ccccf37ec5c08ea903
ToppCell	Adult-Endothelial-endothelial_cell_of_artery-D122\|Adult / Lineage, Cell type, age group and donor	SOST GRK5 MYRIP DIPK1B ARAP3 NOS3 PKN3	1.01e-06	168	139	7	8c3e1e45b422813bcdfa4273b1167db649a312f5
ToppCell	facs-Lung-3m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell-pulmonary_artery_endothelial_cell_l27\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	SOST CDH26 RPS6KB1 MYRIP CDC6 NOS3 PKN3	1.48e-06	178	139	7	9f59a9af232d77bb55603a7776dbf9749ea652f2
ToppCell	facs-Heart-LA-18m-Endothelial-endocardial_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SOST ABCA4 GPR182 MYRIP CBFA2T3 NOS3 PKN3	1.92e-06	185	139	7	1ecfca049c0c1110fd1b2256db7cb7abda6afb04
ToppCell	facs-Heart-LA-18m-Endothelial-endothelial_cell_of_endocardium\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SOST ABCA4 GPR182 MYRIP CBFA2T3 NOS3 PKN3	1.92e-06	185	139	7	b6df1412b579d40ed5df806f9c54bd1fbb9a1e15
ToppCell	Adult-Endothelial-endothelial_cell_of_artery\|Adult / Lineage, Cell type, age group and donor	SOST GRK5 MYRIP DIPK1B ARAP3 NOS3 PKN3	1.99e-06	186	139	7	2d1c4ea2e401db89971582ee54618a8b0c81b8ac
ToppCell	LPS_only-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_3\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	CILP VASN CARMIL1 RYR2 SLIT2 SEMA5B SLIT3	2.21e-06	189	139	7	975e7aa3b862a8b07c2ab8426a14f5cc54998aca
ToppCell	facs-Skin-Anagen-3m-Epithelial-bulge_keratinocyte\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MAPK8IP1 ADAMTS19 PHYHIP ZMIZ1 GSN SGPP1 FZD7	2.54e-06	193	139	7	eba3c70701b051bc1ed1f4db9270cb27a77ffc3e
ToppCell	Children_(3_yrs)-Mesenchymal-matrix_fibroblast_1_cell\|Children_(3_yrs) / Lineage, Cell type, age group and donor	CACNA2D1 GRK5 RYR2 HIVEP3 SLIT2 COL21A1 SLIT3	2.54e-06	193	139	7	99525545552b371c86b18b6ea6f4897dc6e9a9ec
ToppCell	TCGA-Endometrium-Primary_Tumor-Endometrial_Adenocarcinoma-Endometrioid-1\|TCGA-Endometrium / Sample_Type by Project: Shred V9	ADAMTS19 WEE1 GDE1 FREM2 KIF2A CDC6 KNL1	2.54e-06	193	139	7	c2673d86f7d7b849788036032a93a6d136a70040
ToppCell	facs-Skin-Anagen-3m-Epithelial-outer_bulge\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MAPK8IP1 ADAMTS19 PHYHIP ZMIZ1 GSN SGPP1 FZD7	2.62e-06	194	139	7	5d30d3d41d5f19cdf3077cc609aa2738762cb8c5
ToppCell	distal-mesenchymal-Adventitial_Fibroblast-1\|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	CILP VASN RDH10 PHYHIP FAM43B SLIT2 SLIT3	3.21e-06	200	139	7	56e838787385dd282caadeac24fbb0a706bf7f2b
ToppCell	Int-URO-Lymphocyte-B-Plasmablast\|Int-URO / Disease, Lineage and Cell Type	CDH26 N4BP3 FZD7 SPDYE3 PRKAR1B KNL1	1.08e-05	159	139	6	f6ad73b6a3681471efbd4fafd9eb631764c53500
ToppCell	wk_08-11-Mesenchymal-Myofibro_&_SMC-Late_airway_SMC\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	PHYHIP LRP1B SMTN CSAD SPDYE3 SLMAP	1.24e-05	163	139	6	1e8730d75cccf7292010683ab4e81a69d8e3bfa9
ToppCell	facs-Heart-RA-18m-Endothelial-endothelial_cell_of_endocardium\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SOST GPR182 CBFA2T3 ARAP3 NOS3 PKN3	1.48e-05	168	139	6	06dc5b2d356d3a9454b10bba6f3b9ead2a0a7d46
ToppCell	facs-Heart-RA-18m-Endothelial-endocardial_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SOST GPR182 CBFA2T3 ARAP3 NOS3 PKN3	1.48e-05	168	139	6	1002f058a340763e3d8de0bd1f0547a903526ec6
ToppCell	Control-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_2\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	CBFA2T3 LRP1B RYR2 SLIT2 NWD2 SLIT3	1.58e-05	170	139	6	5570c0e825bca77613bf0ebde620cf744fa1cb84
ToppCell	tumor_Lymph_Node_/_Brain-T/NK_cells-CD8+/CD4+_Mixed_Th\|T/NK_cells / Location, Cell class and cell subclass	DCAF1 TSPOAP1 GRK4 GDE1 TRANK1 NOS3	1.74e-05	173	139	6	42c911ed16fabdabef063830e8407192d8bde950
ToppCell	RV-03._Atrial_Cardiomyocyte\|RV / Chamber and Cluster_Paper	WEE1 PABPC5 RYR2 ZNF648 MYO18B	1.97e-05	105	139	5	49e16b11f16e83a7d17d162c14bce991201bcc2a
ToppCell	5'-Adult-SmallIntestine-Mesenchymal-fibroblastic-Stromal_3_(C7+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SOBP RDH10 SLIT2 NWD2 COL21A1 DNAH17	1.98e-05	177	139	6	bd602db857f37869ef76d14c05ef522c509f08ee
ToppCell	droplet-Lung-3m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell-pulmonary_artery_endothelial_cell_l27\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	DPF1 SOST TRIM41 MYRIP MARK4 NOS3	2.25e-05	181	139	6	2c44c41b4e8a75ebdbaeb0c6cc5a03f17c44758c
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ABCA4 APOB LRP1B RYR2 FREM2 TRANK1	2.47e-05	184	139	6	2cbed6462fea2622871bb7e49b0df3d984239281
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ABCA4 APOB LRP1B RYR2 FREM2 TRANK1	2.47e-05	184	139	6	ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ABCA4 APOB LRP1B RYR2 FREM2 TRANK1	2.47e-05	184	139	6	2b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell	LPS_only-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_2\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ADAMTS19 SOBP CBFA2T3 RYR2 SMTN SLIT2	2.47e-05	184	139	6	327ff3ac8d2fecdd5d242bdc34f0dfdb1c59a68b
ToppCell	COVID-19-Heart-Fib_2\|COVID-19 / Disease (COVID-19 only), tissue and cell type	CACNA2D1 CILP SOBP GRK5 GSN SLIT2	2.54e-05	185	139	6	8f95d8e591bf7379d13f5a0545b0cb49e2b1ab5d
ToppCell	LPS-antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_3\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	CACNA2D1 CILP RYR2 SLIT2 SEMA5B SLIT3	2.62e-05	186	139	6	4780af76237d7af2abbe2d8d5530cdf53e3ed0b7
ToppCell	LA-01._Fibroblast_I\|World / Chamber and Cluster_Paper	ADAMTS19 CILP CARMIL1 GRK5 GSN SLIT2	2.70e-05	187	139	6	4ea486991f66c29728d127171a07b81404ec0b78
ToppCell	Endothelial-endothelial_cell_of_artery\|World / Lineage, Cell type, age group and donor	SOST MYRIP DIPK1B ARAP3 NOS3 PKN3	2.87e-05	189	139	6	fdd89c71113ac99b7c800c6def8888e512ff1128
ToppCell	10x5'v1-week_12-13-Mesenchymal_fibro-stroma-endosteal_fibroblast\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	DPF1 ADAMTS19 CACNA2D1 SOBP FAM43B COL21A1	2.87e-05	189	139	6	473b01c9162b12b90a617c600238436177a0d18d
ToppCell	LV-01._Fibroblast_I\|World / Chamber and Cluster_Paper	ADAMTS19 SOBP CARMIL1 GRK5 GSN SLIT2	2.95e-05	190	139	6	12992ec80a7b4f4f17de693f0719ee061a9918fd
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell-\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	CARMIL1 GRK5 RYR2 COL21A1 SLIT3 MYO18B	3.13e-05	192	139	6	bfab13793e54de2550ee171397f7ece0625cdb4a
ToppCell	droplet-Heart-nan-24m-Mesenchymal-cardiomyocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PHYHIP RYR2 FREM2 MOV10L1 CORIN MYO18B	3.13e-05	192	139	6	f6a4e348406a852ace9fb21db8fbdff539217645
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	CARMIL1 GRK5 RYR2 COL21A1 SLIT3 MYO18B	3.13e-05	192	139	6	b54b0d5b88139905521c8d5d58332e89c08d589c
ToppCell	droplet-Heart-nan-24m-Mesenchymal-atrial_cardiomyocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PHYHIP RYR2 FREM2 MOV10L1 CORIN MYO18B	3.13e-05	192	139	6	1a0c25106ae08eac912a4edd5fc1a3ee776f69c2
ToppCell	facs-Brain_Non-Myeloid-Cortex-24m-Neuronal\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CACNA2D1 TSPOAP1 PHYHIP RYR2 TRANK1 PRKAR1B	3.22e-05	193	139	6	be28070c049e7cb68bcd54f582226eb2f5e4bc1c
ToppCell	LA\|World / Chamber and Cluster_Paper	CILP CARMIL1 LRP1B GSN SLIT2 NWD2	3.22e-05	193	139	6	d4bf89437216baf489ea0239136dcedf3b6714af
ToppCell	LV-01._Fibroblast_I\|LV / Chamber and Cluster_Paper	ADAMTS19 SOBP CARMIL1 GRK5 GSN SLIT2	3.22e-05	193	139	6	dc17f3b9758936d428cf17f77a1ce6d4c479b165
ToppCell	facs-Brain_Non-Myeloid-Cortex-24m-Neuronal-nan\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CACNA2D1 TSPOAP1 PHYHIP RYR2 TRANK1 PRKAR1B	3.22e-05	193	139	6	0c652ebe22ce5d2927599dd97ef1920547858395
ToppCell	facs-Brain_Non-Myeloid-Cortex-24m-Neuronal-neuron\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CACNA2D1 TSPOAP1 PHYHIP RYR2 TRANK1 PRKAR1B	3.22e-05	193	139	6	8689a70a33a7c3823dc647d41ac0160e7c3ae396
ToppCell	Children_(3_yrs)-Mesenchymal-matrix_fibroblast_1_cell-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	CACNA2D1 GRK5 RYR2 HIVEP3 SLIT2 SLIT3	3.32e-05	194	139	6	e93de9428c986b8943fc169258847c650cfab0e5
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Ascending_Vasa_Recta_Endothelial_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	CACNA2D1 HIVEP3 ARAP3 SEMA5B MARK4 NOS3	3.32e-05	194	139	6	b490fffc94f005dff9a34ce34d80ca776e3a1387
ToppCell	droplet-Fat-Mat-18m-Endothelial-Cd36+\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SOST MYRIP RYR2 ARAP3 NOS3 PKN3	3.32e-05	194	139	6	74d0eaa76f6d9af14110dfe5b4bf9751b99ff6e3
ToppCell	Sepsis-Int-URO-Lymphocyte-B-Plasmablast\|Int-URO / Disease, condition lineage and cell class	CDH26 N4BP3 TXNDC11 SPDYE3 PRKAR1B RPUSD2	3.52e-05	196	139	6	e65b47d0ce1a5dd05f5f50e1639c8ec76fb42dc8
ToppCell	Children_(3_yrs)-Mesenchymal\|Children_(3_yrs) / Lineage, Cell type, age group and donor	CACNA2D1 GRK5 RYR2 SLIT2 COL21A1 SLIT3	3.52e-05	196	139	6	bc94909f9b2dc08a59eef1914148b69720569c8f
ToppCell	PCW_13-14-Mesenchymal-Mesenchymal_fibroblastic-mes_immature1_(0)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	CARMIL1 GRK5 LRP1B SLIT2 COL21A1 SLIT3	3.62e-05	197	139	6	0034bae02ee7fcfea520d453ca3c842ab6963b12
ToppCell	PCW_10-12-Mesenchymal-Mesenchymal_fibroblastic-mes_immature1_(0)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	CARMIL1 GRK5 LRP1B SLIT2 COL21A1 SLIT3	3.62e-05	197	139	6	11a4c417f035e554431a8f03be13b5eefa3530c0
ToppCell	3'-Adult-LymphNode-Mesenchymal-fibroblastic-mLN_Stroma_(FMO2+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CILP PHYHIP LRP1B GSN SLIT2 SLIT3	3.72e-05	198	139	6	abac765c4f6864bdb1700bc546c3b9771edc25c3
ToppCell	Tracheal-10x5prime-Endothelial-Endothelia_lymphatic\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	GPR182 ARAP3 MOV10L1 PRKAR1B CCL21 NOS3	3.72e-05	198	139	6	05429f18e1d74880c1835568c86177f661b3477a
ToppCell	Tracheal-10x5prime-Endothelial-Endothelia_lymphatic-Endothelia_Lymphatic\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	GPR182 ARAP3 MOV10L1 PRKAR1B CCL21 NOS3	3.72e-05	198	139	6	306e28d31fd587409a12dcccc6b2abd7dc9c2e0a
ToppCell	3'-Adult-LymphNode-Mesenchymal-fibroblastic\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CILP PHYHIP LRP1B GSN SLIT2 SLIT3	3.72e-05	198	139	6	ff57addcbdd53e5d2d0c80ec76b5eab3b3a67ca2
ToppCell	3'-Adult-LymphNode-Mesenchymal\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CILP PHYHIP LRP1B GSN SLIT2 SLIT3	3.72e-05	198	139	6	698166b4ca173176ed563af6a1efc8c7d0a18e0b
ToppCell	LPS_IL1RA-Mesenchymal_fibroblastic-Fibroblasts-Activated_MatrixFB\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	RDH10 RYR2 HIVEP3 SLIT2 COL21A1 SLIT3	3.83e-05	199	139	6	8b86c69aaf60feff53aa782559cfece7342a23de
ToppCell	LPS_anti-TNF-Mesenchymal_myocytic-Pericyte-Pericyte_3\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	CILP VASN RYR2 SMTN SLMAP MYO18B	3.93e-05	200	139	6	9169a9ec8e9ab95d90a64c5a19ac666a5cf82313
ToppCell	5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-Adventitial_fibroblasts_L.2.1.0.1\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CILP VASN PHYHIP FAM43B GSN SLIT3	3.93e-05	200	139	6	3e6730c9ed7003a4acf501f699a4965a7a50f946
ToppCell	distal-1-mesenchymal-Adventitial_Fibroblast\|1 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	CILP VASN PHYHIP FAM43B SLIT2 SLIT3	3.93e-05	200	139	6	738060ed65fa5473fdb39e686f7cdecc059ed92c
ToppCell	LPS_only-Mesenchymal_myocytic-Pericyte-Pericyte_3\|LPS_only / Treatment groups by lineage, cell group, cell type	CILP VASN RYR2 SMTN SLIT2 MYO18B	3.93e-05	200	139	6	7c62678cf408aaaf98d6df0fb27814d2007c4521
ToppCell	distal-mesenchymal-Adventitial_Fibroblast\|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	CILP VASN PHYHIP FAM43B SLIT2 SLIT3	3.93e-05	200	139	6	687cfada2d0977e8985e0a73a5804f84f2ca9c52
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW12-Neuronal-Interneuron\|GW12 / Sample Type, Dataset, Time_group, and Cell type.	GRK5 TMEM79 SLIT2 TRANK1 PRICKLE3	4.56e-05	125	139	5	eafc39072467e209c9fe3a4fa41cb09507a42e82
ToppCell	TCGA-Cervix-Primary_Tumor-Cervical_Carcinoma-Cervical_Squamous_Cell_Carcinoma-4\|TCGA-Cervix / Sample_Type by Project: Shred V9	MAPK8IP1 ABCA4 SOBP FREM2 FBN3	5.11e-05	128	139	5	3ca9ae69fb8cb7f8acb7540aa71778bc917da4df
ToppCell	TCGA-Cervix-Primary_Tumor-Cervical_Carcinoma-Cervical_Squamous_Cell_Carcinoma\|TCGA-Cervix / Sample_Type by Project: Shred V9	GRK6 RTN4R CSAD DENND4B KIF18B	5.70e-05	131	139	5	88b3298110bc2333ffa202a3f41ac0d24e2308c7
ToppCell	LA-10._Endothelium_II\|LA / Chamber and Cluster_Paper	MYRIP UBASH3A ARAP3 CCL21 PKN3	6.35e-05	134	139	5	048fa6ccf305d22d9a53db4ab385f39f558010d8
ToppCell	E16.5-samps-Mesenchymal-Matrix_fibroblast-_fetal-Intermediate_Fibroblast\|E16.5-samps / Age Group, Lineage, Cell class and subclass	CDH26 HIVEP3 ERFE SERINC4 PRKAR1B	7.05e-05	137	139	5	dd5364a1002650d21e0c83d8c701b5f7b09d1c19
ToppCell	facs-Trachea-18m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l20-23\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	FAM43B TRANK1 MOV10L1 CORIN ZNF541	8.93e-05	144	139	5	e9d62f202f0fa8747961036ef0eafed91fe8a42f
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	MAPK8IP1 CILP RDH10 LRP1B TRMT2A	1.05e-04	149	139	5	7e295b2b82dea0754e98f8cef788e2781e5d641f
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	MAPK8IP1 CILP RDH10 LRP1B TRMT2A	1.05e-04	149	139	5	b4f77dc5f9d08b249fe5cd9a0acf86308c528ef4
ToppCell	BAL-Control-cDC_12\|Control / Compartment, Disease Groups and Clusters	WEE1 GRK5 SLIT2 FAM161A CDC6	1.22e-04	154	139	5	0121d08cc527aed9b3e11ff62bb9012916f5c56b
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Cycling_Endothelial_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	KIF2A MYO18B KIF18B NOS3 KNL1	1.30e-04	156	139	5	b3f10cd044f24807576e7d56e51df7064dbf6c50
ToppCell	facs-Marrow-T-cells-24m-Lymphocytic-pre_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CACNA2D1 KBTBD8 FREM2 MMEL1 MOV10L1	1.38e-04	158	139	5	f296ca24fdedc33f1d24b79e7660763114ce7fa3
ToppCell	facs-Marrow-T-cells-24m-Lymphocytic-precursor_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CACNA2D1 KBTBD8 FREM2 MMEL1 MOV10L1	1.38e-04	158	139	5	8c7108f2c40d97a317762ba0b8eca76542b2ebaf
ToppCell	Transplant_Alveoli_and_parenchyma-Epithelial-Basal_2\|Epithelial / Tissue, Lineage and Cell class of Lung Cells from 10X	DPF1 CACNA2D1 ADAMTS13 CBFA2T3 RYR1	1.60e-04	163	139	5	f21951e63188eb0c04675a8f81a0da495c26c007
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_G2M\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	DOK3 SMTN CDC6 KIF18B KNL1	1.64e-04	164	139	5	1642a67c66eeb77a218e7814e3cfe517d9822955
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	DOK3 SMTN CDC6 KIF18B KNL1	1.64e-04	164	139	5	25758fb8112baf296264122d5d4121f1ebb3d0fa
ToppCell	facs-Brain_Non-Myeloid-Cerebellum_-18m-Neuronal-SPN_Neuron_STR\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RYR1 TRANK1 SEMA5B GAL3ST3 ZNF541	1.69e-04	165	139	5	1b7dfa173e83aa8c46a3153a3261866c065c3b73
ToppCell	Endothelial-B-Donor_01\|World / lung cells shred on cell class, cell subclass, sample id	GPR182 SMTN ARAP3 CCL21 PKN3	1.69e-04	165	139	5	b6893882472aeb0d18e26f47eaec9d53688afcde
ToppCell	facs-Brain_Non-Myeloid-Cerebellum_-18m-Neuronal-medium_spiny_neuron\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RYR1 TRANK1 SEMA5B GAL3ST3 ZNF541	1.69e-04	165	139	5	b4f7d33af7d053ec07b01bd67d861600a9c4822e
ToppCell	Children_(3_yrs)-Mesenchymal-vascular_smooth_muscle_cell-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	CACNA2D1 GRK5 LRRC10B RYR2 SLIT3	1.69e-04	165	139	5	8a82e20c9b1156bb4bbc16f7785abb04458d671b
ToppCell	356C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_6\|356C / Donor, Lineage, Cell class and subclass (all cells)	SANBR UBASH3A CDAN1 ERFE EME2	1.74e-04	166	139	5	c4f7ea1cad962b1d6ad77423d15978b68a0d6f1d
ToppCell	CV-Mild-3\|Mild / Virus stimulation, Condition and Cluster	NEIL1 N4BP3 SPDYE3 SETD7 KNL1	1.74e-04	166	139	5	5599f90fc0e15a3670b03187085eba91228390a2
ToppCell	tumor_Lymph_Node_/_Brain-T/NK_cells-CD8+/CD4+_Mixed_Th\|tumor_Lymph_Node_/_Brain / Location, Cell class and cell subclass	DCAF1 TSPOAP1 GRK4 UBASH3A TRANK1	1.79e-04	167	139	5	c0c944eae0514dc8e00d0c2892a0792e157695ec
ToppCell	facs-Aorta-Heart-24m-Endothelial-endocardial_endothelial_cells\|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SOST GPR182 MYRIP ACSM4 PKN3	1.84e-04	168	139	5	edbab94f14e16a1a76546a18fe777a183080d1de
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal--glomerular_mesenchymal_cell-Renin-positive_Juxtaglomerular_Granular_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	GRK5 LRRC10B COL21A1 SLIT3 MYO18B	1.94e-04	170	139	5	99dd734c0972a40d5381e8e2d96bdaa31f6d06e6
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal--glomerular_mesenchymal_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	GRK5 LRRC10B COL21A1 SLIT3 MYO18B	1.94e-04	170	139	5	3a14eeae221b8bb0bd0dadcb8e7a603431240a1e
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal-\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	GRK5 LRRC10B COL21A1 SLIT3 MYO18B	1.94e-04	170	139	5	cdb6fad277f284c3fd5a6f45672a8edc24715882
ToppCell	Control-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_3\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	CARMIL1 RYR2 FREM2 SEMA5B SLIT3	1.99e-04	171	139	5	4ede831aed364cb5271f49a8b09bb6d0452f9b35
ToppCell	Children_(3_yrs)-Endothelial-endothelial_cell_of_artery-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	MYRIP DIPK1B ARAP3 NOS3 PKN3	1.99e-04	171	139	5	1597459c971d6befa991d59dc66b41b6a522f797
ToppCell	356C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_6\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	SANBR UBASH3A CDAN1 ERFE EME2	2.05e-04	172	139	5	a9e13aa36087170dadca421ba9de588e5a1cf715
ToppCell	Adult-Mesenchymal-vascular_smooth_muscle_cell\|Adult / Lineage, Cell type, age group and donor	CACNA2D1 GRK5 RYR2 SEMA5B SLIT3	2.05e-04	172	139	5	c62cad0f4212d1e9ea1ec3143ad3c4e06aff0ebf
ToppCell	facs-Heart-Unknown-3m-Mesenchymal-atrial_myocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PHYHIP RYR2 MOV10L1 CORIN MYO18B	2.05e-04	172	139	5	ee8ce9e8c9a6d3ee2be113f77743958005f4b3f0
ToppCell	Adult-Mesenchymal-pericyte_cell-D231\|Adult / Lineage, Cell type, age group and donor	VASN RYR2 SMTN SEMA5B SLIT3	2.05e-04	172	139	5	858cee96c1c06160863b4adcd7023c0d678bd50f
ToppCell	facs-Heart-Unknown-3m-Mesenchymal-atrial_cardiomyocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PHYHIP RYR2 MOV10L1 CORIN MYO18B	2.05e-04	172	139	5	bd468a7ea6ec832dcf6a816a1e0c03fa0f176dad
ToppCell	E12.5-Endothelial-proliferative_endothelial_cell-proliferative_endothelial_cell\|E12.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	CDH26 GPR182 N4BP3 ARAP3 NOS3	2.05e-04	172	139	5	ba99688e9f46671deccf824b1e77c6db0742d7df
ToppCell	E12.5-Endothelial-proliferative_endothelial_cell\|E12.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	CDH26 GPR182 N4BP3 ARAP3 NOS3	2.05e-04	172	139	5	2136170f6e1204734cec7dbf7b32e7d5179b92b5
ToppCell	droplet-Pancreas-Exocrine-21m-Epithelial-pancreatic_ductal_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CCDC187 ERFE TRANK1 DMRT2 KIF18B	2.16e-04	174	139	5	a0ccda8fd6f55251cdeff24cf66e72e4a31d2104
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Degenerative_Fibroblast-Degenerative_Fibroblast_26.46.91\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	PHYHIP CCDC187 N4BP3 FZD7 GTF3C1	2.22e-04	175	139	5	3031f1eef3cfef8a7e5f57e567cb0868d06cac38
ToppCell	facs-Trachea-24m-Endothelial-endothelial_cell_of_trachea-tracheal_endothelial_cell-tracheal_endothelial_cell_l54\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	GPR182 CBFA2T3 CCL21 NOS3 PKN3	2.28e-04	176	139	5	460cb302c5b3d609c65b924e1d4e8ea057a68485
ToppCell	PBMC-Convalescent-Lymphocyte-B-B_cell-B_naive-B_activate-7\|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	NEIL1 CBFA2T3 N4BP3 MAST2 DNAJC11	2.28e-04	176	139	5	dde46f06f6fc3f7ba83be91a0ee6231790955e3e
ToppCell	PND07-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF1-AF1_prolif\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CACNA2D1 GSN HIVEP3 SLIT2 CDC6	2.28e-04	176	139	5	cb8fd56a4f935cdda19d7ab43382cdda7c307667
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Cycling_Endothelial_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	CDC6 KIF18B NOS3 PKN3 KNL1	2.34e-04	177	139	5	73ba0f0b4b33f10e9f036d6d9befa48a1258e682
ToppCell	3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.0.5\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CDH26 WEE1 RDH10 ZNF648 RAI1	2.46e-04	179	139	5	6e965e424eebef50f0202cff75f458be395cfca1
Disease	Abnormality of the urinary system	ZMIZ1 TRRAP	2.02e-05	2	133	2	C4021821
Disease	alcohol use disorder (implicated_via_orthology)	DPF1 GRK4 GRK5 GRK6 PDPK2P RYR1 RYR2	3.05e-05	195	133	7	DOID:1574 (implicated_via_orthology)
Disease	alkaline phosphatase measurement	WNT3 CARMIL1 TRIM41 APOB ADAMTS13 ZMIZ1 FAM43B TXNDC11 GSN HIVEP3 NWD2 TRANK1 MARK4 PRKAR1A RAI1	5.57e-05	1015	133	15	EFO_0004533
Disease	Lipidemias	NEIL1 APOB NOS3	5.81e-05	17	133	3	C1706412
Disease	Hyperlipidemia	NEIL1 APOB NOS3	5.81e-05	17	133	3	C0020473
Disease	congenital myopathy 1A (implicated_via_orthology)	RYR1 RYR2	6.03e-05	3	133	2	DOID:3529 (implicated_via_orthology)
Disease	malignant hyperthermia (implicated_via_orthology)	RYR1 RYR2	6.03e-05	3	133	2	DOID:8545 (implicated_via_orthology)
Disease	treatment resistant depression, response to antidepressant	OPN3 HIVEP3 SLIT3	1.12e-04	21	133	3	EFO_0009854, GO_0036276
Disease	calcium measurement	GRK5 SANBR GPATCH2 ZMIZ1 LRP1B RNF215 SEMA5B PRICKLE3 MARK4 MYO18B PKN3	1.35e-04	628	133	11	EFO_0004838
Disease	congenital diaphragmatic hernia (biomarker_via_orthology)	SLIT2 SLIT3 NOS3	1.69e-04	24	133	3	DOID:3827 (biomarker_via_orthology)
Disease	level of Sterol ester (27:1/18:2) in blood serum	APOB ZGLP1 MARK4	2.16e-04	26	133	3	OBA_2045194
Disease	celiac disease	WNT3 ZMIZ1 UBASH3A MMEL1 CCL21	2.72e-04	126	133	5	EFO_0001060
Disease	aortic valve disease (implicated_via_orthology)	ADAMTS19 NOS3	2.99e-04	6	133	2	DOID:62 (implicated_via_orthology)
Disease	Malignant neoplasm of breast	ADAMTS19 ABCA4 KBTBD8 ZMIZ1 HELQ GSN ARAP3 TRMT2A SEMA5B PRICKLE3 SLC6A5 ZFYVE26 NOS3 ZNF541	3.61e-04	1074	133	14	C0006142
Disease	uridine measurement	ABCA4 FAM43B SLIT2	4.04e-04	32	133	3	EFO_0010546
Disease	gestational age	HIVEP3 SLIT2 UBR5 MOV10L1 SLMAP	4.14e-04	138	133	5	EFO_0005112
Disease	pulmonary hypertension (biomarker_via_orthology)	GPR182 RYR1 RYR2 NOS3	4.79e-04	80	133	4	DOID:6432 (biomarker_via_orthology)
Disease	triacylglycerol 58:6 measurement	LRP1B HIVEP3	5.55e-04	8	133	2	EFO_0010440
Disease	Cardiovascular Diseases	GRK5 APOB NOS3	5.73e-04	36	133	3	C0007222
Disease	ceramide measurement	APOB ZMIZ1 RNF215 SGPP1 CORIN FBN3	7.08e-04	235	133	6	EFO_0010222
Disease	Kunitz-type protease inhibitor 2 measurement	DPF1 RYR1	8.86e-04	10	133	2	EFO_0008200
Disease	lymphocyte percentage of leukocytes	TSPOAP1 GRK5 ADAMTS13 ZMIZ1 FAM43B CBFA2T3 GTF3C1 UBR5 MARK4 GAB3	8.91e-04	665	133	10	EFO_0007993
Disease	Adenocarcinoma of large intestine	PMS2 TRRAP UBR5 MARK4	9.51e-04	96	133	4	C1319315
Disease	severe acute respiratory syndrome, COVID-19	CACNA2D1 PMS2 GRK4 MYRIP HELQ LRP1B SEMA5B EIF2AK1	9.82e-04	447	133	8	EFO_0000694, MONDO_0100096
Disease	amino acid measurement	ADAMTS19 CACNA2D1 CARMIL1 RTN4R RYR2 SLIT2 SLIT3 MARK4 SLC6A5 SETD7	1.03e-03	678	133	10	EFO_0005134
Disease	rheumatoid arthritis, anti-citrullinated protein antibody seropositivity, rheumatoid factor seropositivity measurement	UBASH3A TXNDC11 HIVEP3 SPDYE3 CCL21	1.06e-03	170	133	5	EFO_0000685, EFO_0007791, EFO_0007837
Disease	Tachycardia, Ventricular	RYR2 NOS3	1.08e-03	11	133	2	C0042514
Disease	peanut allergy measurement, parental genotype effect measurement	RYR1 PWWP3A	1.08e-03	11	133	2	EFO_0005939, EFO_0007017
Disease	Dental enamel hypoplasia	ZMIZ1 SEMA5B	1.29e-03	12	133	2	EFO_1001304
Disease	Colorectal Carcinoma	PMS2 ABCA4 SALL3 RPS6KB1 APOB ZMIZ1 CBFA2T3 SMTN HIVEP3 ARAP3	1.34e-03	702	133	10	C0009402
Disease	gallbladder cancer (is_implicated_in)	APOB LRP1B	1.52e-03	13	133	2	DOID:3121 (is_implicated_in)
Disease	PR interval	CARMIL1 ZMIZ1 RYR2 HIVEP3 FREM2 CEP95 NUDCD1 EME2	1.87e-03	495	133	8	EFO_0004462
Disease	African Burkitt's lymphoma	SALL3 FTCD	2.04e-03	15	133	2	C0343640
Disease	Burkitt Leukemia	SALL3 FTCD	2.04e-03	15	133	2	C4721444
Disease	ovarian cancer (is_implicated_in)	PMS2 APOB NOS3	2.08e-03	56	133	3	DOID:2394 (is_implicated_in)
Disease	platelet component distribution width	WEE1 CARMIL1 GRK5 ZMIZ1 TRANK1 TBC1D10A MOV10L1 MARK4 KIF2A NOS3	2.28e-03	755	133	10	EFO_0007984
Disease	Pre-Eclampsia	CORIN NOS3	2.32e-03	16	133	2	C0032914
Disease	Malignant lymphoma, lymphocytic, intermediate differentiation, diffuse	WNT3 UBR5	2.32e-03	16	133	2	C0334634
Disease	sickle cell anemia (is_implicated_in)	APOB NOS3	2.32e-03	16	133	2	DOID:10923 (is_implicated_in)
Disease	Insulin Resistance	NEIL1 PRKAR1A NOS3	2.54e-03	60	133	3	C0021655
Disease	Insulin Sensitivity	NEIL1 PRKAR1A NOS3	2.54e-03	60	133	3	C0920563
Disease	erythritol measurement	CACNA2D1 MAST2	2.62e-03	17	133	2	EFO_0021171
Disease	immature granulocyte count	MARK4 PKN3	2.62e-03	17	133	2	EFO_0803542
Disease	essential hypertension (is_implicated_in)	GRK4 NOS3	2.94e-03	18	133	2	DOID:10825 (is_implicated_in)
Disease	lysophosphatidylcholine 22:6 measurement	CACNA2D1 FZD7	2.94e-03	18	133	2	EFO_0010365
Disease	cerebral infarction (is_marker_for)	APOB GSN	3.28e-03	19	133	2	DOID:3526 (is_marker_for)
Disease	Microcephaly	ZMIZ1 TRRAP KIF2A	3.47e-03	67	133	3	C0025958
Disease	energy expenditure measurement	CACNA2D1 GPATCH2	3.63e-03	20	133	2	EFO_0008005
Disease	alpha-tocopherol measurement	CACNA2D1 RNF215	3.63e-03	20	133	2	EFO_0007898
Disease	ascending aortic diameter	CBFA2T3 RYR2 HIVEP3 COL21A1	3.77e-03	140	133	4	EFO_0021787
Disease	vital capacity	ADAMTS19 WNT3 GRK5 APOB ZMIZ1 RYR2 DMRT2 COL21A1 SLMAP GAB3 MYO18B CCL21 FBN3	3.93e-03	1236	133	13	EFO_0004312
Disease	left atrial function	CILP MYO18B	4.00e-03	21	133	2	EFO_0004294
Disease	Metabolic Syndrome X	NEIL1 NOS3	4.00e-03	21	133	2	C0524620
Disease	complement factor H-like 1 protein measurement	FAM43B FREM2	4.39e-03	22	133	2	EFO_0600092

Protein segments in the cluster

Peptide	Gene	Start	Entry
ALGPPSRLCKASFLR	ADAD2	511	Q8NCV1
GCSIPAILFLPRKRS	CCL21	56	O00585
EKDTLRPCPRSRGLL	CCDC187	616	A0A096LP49
RCREEPPRLLGSRFQ	ARAP3	1231	Q8WWN8
KIFEPCGRPAVDRLN	ABCA4	936	P78363
KRRLNILEDPRLRPC	DPF1	81	Q92782
CRLEQLPGIFPKDVR	C17orf78	26	Q8N4C9
EGEIALRLKPTRPFC	ACSM4	416	P0C7M7
CKINGLSPRDRPRRS	FBN3	2676	Q75N90
VLFCPFSKRLQGRLP	DIPK1B	11	Q5VUD6
FCQRKSPGAVRALLP	CDAN1	936	Q8IWY9
LLKTLPPARCRAGAQ	ADAMTS13	776	Q76LX8
AGTKLPCPRDSALRR	NWD2	6	Q9ULI1
RRPSEGRLPNCRATK	RAI1	1161	Q7Z5J4
SNSFGRNLPPKRRCR	RBM27	266	Q9P2N5
PRPGTSLELCRKALA	TSPOAP1	196	O95153
TLIRARERDCIGPKP	ADAMTS19	1011	Q8TE59
NCSLRVKRPLLDPRF	NUDCD1	6	Q96RS6
KFSPAGPILSIRICR	PABPC1L2A	21	Q5JQF8
RERPSPCNGRKIRVL	DCAF1	961	Q9Y4B6
PLFGLKLFRNLTPRC	DNAJC11	221	Q9NVH1
TRPICRGKLFNNLKP	KIAA0100	1296	Q14667
SGLICPEFKRPRDIA	LRP1B	3961	Q9NZR2
FRQRKGPFCPTLRLL	MCTS2	71	A0A3B3IRV3
RLPPCDEFVGARRSK	LZTR1	56	Q8N653
LAVKRILSGDCRPLP	MOV10L1	751	Q9BXT6
PGPRLALCFVDIRRF	NEIL1	106	Q96FI4
QCKDTLSLRPPRAGL	MAPK8IP1	61	Q9UQF2
RDKRLSLNLPCRFSP	GAB3	366	Q8WWW8
VPRAPLRRLLNAKCA	FAM43B	231	Q6ZT52
AQRPGRLSPKRFPCD	FREM2	116	Q5SZK8
RKRGNRRYCPIPDVL	EHHADH	551	Q08426
GPRAPRVEAAFLCRL	ERFE	196	Q4G0M1
LFLSARNCGPERPRE	GPR119	306	Q8TDV5
RGPEKIRPECFELLR	RPS6KB1	81	P23443
LLSRERRKGPAPCDR	DOK3	481	Q7L591
VRRCSLGIFLPRLPN	KNL1	1671	Q8NG31
LGIFLPRLPNKRNCS	KNL1	1676	Q8NG31
FNKLERLPDGLCRLP	LRRC10B	76	A6NIK2
RRIGTNLPLKPCARA	MTFR1L	26	Q9H019
RAPDPRVICSRKGRV	PDPK2P	371	Q6A1A2
RGKQLPRLASRLCFL	MMEL1	51	Q495T6
PPACGARQLSKLKRF	CBFA2T3	166	O75081
RQSFLPCLRRGSLPD	KIF18B	651	Q86Y91
TGRVFKLCKPPNDLR	KBTBD8	311	Q8NFY9
PRRCLGSLVFPRKLQ	NOS3	96	P29474
LLSKVRLCGGRPARP	FGF11	46	Q92914
KKFRPAGPLRFTRIC	PABPC5	36	Q96DU9
RPFLPRRGLIFCSRA	PRICKLE3	351	O43900
CIRALGRNKPHTPFR	KIF2A	491	O00139
LRLLRCQRPAKDLPA	OPN3	326	Q9H1Y3
RGRPAFPFSCPRQLK	FZD7	201	O75084
LLRRCFGDEPLLRPA	GAL3ST3	331	Q96A11
QCDRFKPIRTGISPL	APOB	211	P04114
PSCRALQVLKPRDRI	GDE1	51	Q9NZC3
GAEPRKLSRTPKCAR	DMRT2	111	Q9Y5R5
RAELPENLKALFRPC	DNAH17	1956	Q9UFH2
RTGQLPESLRKRCPV	EIF2AK1	541	Q9BQI3
DIKRLTPRFTLCPNG	CACNA2D1	496	P54289
CFSVIARRDPFRKGP	COL21A1	941	Q96P44
CNSPFPQRPRKRLTE	CEP95	351	Q96GE4
LFRPLAKRCCLQPRD	CERS1	81	P27544
LPLSPRKRLGDDNLC	CDC6	51	Q99741
ERCRRAGSPKPVLRA	CORIN	11	Q9Y5Q5
QRYPDCKQRGLRTLP	CSAD	166	Q9Y600
CKQRGLRTLPPLALF	CSAD	171	Q9Y600
VCQLPRPGLRGVLFR	MARK4	716	Q96L34
VRRRCSGLLDAPRFP	MAST2	926	Q6P0Q8
ERLVFCERGKLQPPR	CDH26	361	Q8IXH8
ICYRRGRDKPPLVEL	DENND4B	91	O75064
ARGPLKCVKLDRPRF	PRKAR1A	341	P10644
ARGPLKCVKLDRPRF	PRKAR1B	341	P31321
GTCLRKIFPGLSPVR	CARMIL1	111	Q5VZK9
PGSRVSCRRDLGKPL	ARRDC1-AS1	141	Q9H2J1
PPRLFACSNKIGRFV	GSN	666	P06396
PRRVGPDLSRRICLF	EME2	351	A4GXA9
RVSLPKRNRPSLGCI	HELQ	11	Q8TDG4
LSPRRKSPVRCAGVN	FAM161A	491	Q3B820
CTGDIKRRRKAAPLP	GPATCH2	436	Q9NW75
PIGRRLFRQFCDTKP	GRK4	61	P32298
PIGRLLFRQFCETRP	GRK5	61	P34947
PIGRLLFREFCATRP	GRK6	61	P43250
PVREKFCNLIGPRDR	DHX40	236	Q8IX18
PFSLLFLSRERGKCP	SALL3	961	Q9BXA9
LLIRKPECFGPALRG	RYR1	2356	P21817
VRLLIRRPECFGPAL	RYR2	2321	Q92736
RVPPDLFRRLTGQFC	BVES	136	Q8NE79
RLGLDSLCPFSPKER	FTCD	306	O95954
RKPPRLQDFRCLAVL	PKN3	551	Q6P5Z2
ECPAKKRPRLDGSQR	PWWP3A	296	Q2TAK8
RVDPRGKPCETVFQR	RPUSD2	336	Q8IZ73
PCSLPQRLAGRDLKR	RTN4R	286	Q9BZR6
CRAPSNRVKGIPFRP	TRMT2A	551	Q8IZ69
CRKSFPRRSFRPNLQ	TRIM41	186	Q8WV44
QSFNDPLLCGKIRPR	SUPT20HL1	356	Q3ZLR7
PGRFIERLKLVCSPQ	SLC6A5	741	Q9Y345
LEPNCAKPRRARTAF	NKX1-2	156	Q9UD57
TACRLRQPGQPKSRR	GPR182	241	O15218
RQPGQPKSRRHCLLL	GPR182	246	O15218
RRCRLSRAAQGLPDP	RNF215	306	Q9Y6U7
ARFQRLCGVEAPPRR	SGPP1	21	Q9BX95
PRFGPIKCIRTLRAV	SETD7	311	Q8WTS6
PKGSLGDRFCRDRLP	PHYHIP	241	Q92561
RLVPGLTPKECAKRF	SANBR	41	Q6NSI8
LLCPGGEAPRARKVR	SOST	146	Q9BQB4
FRGCRIRKEIEPFLP	RDH10	251	Q8IZV5
QSFNDPLLCGKIRPR	SUPT20HL2	356	P0C7V6
RFRIPGLCPDGKSIL	CILP	261	O75339
VLRAGKKTFLPPLCR	COA8	16	Q96IL0
RRIVSGNPRCQKPFF	SLIT3	681	O75094
TLVFIRRCKPEGPKR	TEX13D	426	A0A0J9YY54
PPRRAGAACTLRQKL	WEE1	11	P30291
RRLCTYLRGQLKEPG	TEP1	1216	Q99973
DLEPPLKRRCLRIRN	SOBP	856	A7XYQ1
PPRRSLGCKRKRECL	SPDYE3	116	A6NKU9
EPIKIGRSVARCRPA	SLMAP	26	Q14BN4
SFLSIAPCIRLKQPR	SERINC4	271	A6NH21
VRRLPFGKCRIPNNS	SPPL2B	271	Q8TCT7
LLCFSALRPFGEPRR	TMEM79	261	Q9BSE2
RKCFLVRQASLSRPP	HIVEP3	1041	Q5T1R4
GSIPGLVPKQLRFCR	WNT3	46	P56703
NRLRCIPPRTFDGLK	SLIT2	811	O94813
LGFRVRKRTCTNPEP	SEMA5B	871	Q9P283
TRCHFPPKNAGRLLL	VASN	326	Q6EMK4
LRSLFQARAKLPPVC	MYO18B	1126	Q8IUG5
FINRRPCDPAKVCRL	PMS2	291	P54278
RLPTVLFFPCNRKDL	TXNDC11	761	Q6PKC3
PSKRRGARAFRCIKP	YY1AP1	576	Q9H869
RCLRGGRAFQKPSKP	ZNF648	251	Q5T619
VTRKEPGALRPCSLR	TRANK1	671	O15050
KFQLRCTPVPARLRP	GTF3C1	1676	Q12789
LRCQKGIPPSLRGRA	TBC1D10A	106	Q9BXI6
RPRKQLNPCRGTERV	ZGLP1	126	P0C6A0
FPNLGCLLDREFRPL	ZFYVE26	351	Q68DK2
PAFLSGLRCAQPLIR	TRRAP	2441	Q9Y4A5
SKCPRAFGRPATLRR	ZSCAN5C	471	A6NGD5
KRADVAGPRPCQRSL	SMTN	286	P53814
CLLKQEPRGRRLSPQ	nan	151	Q8N7P7
KCPITFRRIQLPARG	ZMIZ1	741	Q9ULJ6
PRPGKNTEARLNCFR	UBR5	2516	O95071
FGTEFCKPLRQVLRP	ZNF541	876	Q9H0D2
LNFPCSLPRRSRGIK	UBASH3A	431	P57075
ILPPELGDCRALKRA	LRRC8C	766	Q8TDW0
SLPERGRFDKCRIRP	N4BP3	101	O15049
ALSKLCPRSRALPRN	MYRIP	406	Q8NFW9