Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	ubiquitin-like protein transferase activity	RAG2 RNF186 JADE2 FBXW2 ZMIZ1 TTC3 TRIM32 ZMIZ2 RNFT1 ANKIB1 FBXO15	8.03e-05	512	105	11	GO:0019787
GeneOntologyMolecularFunction	aminoacyltransferase activity	RAG2 RNF186 JADE2 FBXW2 ZMIZ1 TTC3 TRIM32 ZMIZ2 RNFT1 ANKIB1 FBXO15	1.13e-04	532	105	11	GO:0016755
GeneOntologyMolecularFunction	ubiquitin-like protein ligase activity	RAG2 RNF186 JADE2 ZMIZ1 TRIM32 ZMIZ2 RNFT1 ANKIB1 FBXO15	2.53e-04	398	105	9	GO:0061659
Domain	Sushi	SELP CFH SVEP1 C4BPA CSMD1	1.07e-05	52	105	5	PF00084
Domain	CCP	SELP CFH SVEP1 C4BPA CSMD1	1.30e-05	54	105	5	SM00032
Domain	SUSHI	SELP CFH SVEP1 C4BPA CSMD1	1.55e-05	56	105	5	PS50923
Domain	Sushi_SCR_CCP_dom	SELP CFH SVEP1 C4BPA CSMD1	1.69e-05	57	105	5	IPR000436
Domain	-	RNF186 KDM5A JADE2 JADE1 ZMIZ1 TTC3 TRIM32 ZMIZ2 RNFT1 ANKIB1 USP3	4.49e-05	449	105	11	3.30.40.10
Domain	Znf_RING/FYVE/PHD	RNF186 KDM5A JADE2 JADE1 ZMIZ1 TTC3 TRIM32 ZMIZ2 RNFT1 ANKIB1 USP3	5.47e-05	459	105	11	IPR013083
Domain	Runt	RUNX2 RUNX3	9.36e-05	3	105	2	PF00853
Domain	RUNT	RUNX2 RUNX3	9.36e-05	3	105	2	PS51062
Domain	Transferrin	TF MELTF	9.36e-05	3	105	2	PF00405
Domain	Transferrin	TF MELTF	9.36e-05	3	105	2	IPR016357
Domain	TF_Runt-rel_RUNX	RUNX2 RUNX3	9.36e-05	3	105	2	IPR016554
Domain	TRANSFERRIN_LIKE_4	TF MELTF	9.36e-05	3	105	2	PS51408
Domain	RunxI	RUNX2 RUNX3	9.36e-05	3	105	2	PF08504
Domain	Runt_dom	RUNX2 RUNX3	9.36e-05	3	105	2	IPR013524
Domain	TRANSFERRIN_LIKE_1	TF MELTF	9.36e-05	3	105	2	PS00205
Domain	TRANSFERRIN_LIKE_2	TF MELTF	9.36e-05	3	105	2	PS00206
Domain	TRANSFERRIN_LIKE_3	TF MELTF	9.36e-05	3	105	2	PS00207
Domain	Transferrin_Fe_BS	TF MELTF	9.36e-05	3	105	2	IPR018195
Domain	RunxI_C_dom	RUNX2 RUNX3	9.36e-05	3	105	2	IPR013711
Domain	Runx_central_dom	RUNX2 RUNX3	9.36e-05	3	105	2	IPR027384
Domain	TR_FER	TF MELTF	9.36e-05	3	105	2	SM00094
Domain	-	RUNX2 RUNX3	9.36e-05	3	105	2	4.10.770.10
Domain	Transferrin-like_dom	TF MELTF	9.36e-05	3	105	2	IPR001156
Domain	AML1_Runt	RUNX2 RUNX3	9.36e-05	3	105	2	IPR000040
Domain	p53/RUNT-type_TF_DNA-bd	RUNX2 RUNX3	4.63e-04	6	105	2	IPR012346
Domain	-	RUNX2 RUNX3	4.63e-04	6	105	2	2.60.40.720
Domain	zf-MIZ	ZMIZ1 ZMIZ2	6.45e-04	7	105	2	PF02891
Domain	ZF_SP_RING	ZMIZ1 ZMIZ2	6.45e-04	7	105	2	PS51044
Domain	EPL1	JADE2 JADE1	8.57e-04	8	105	2	PF10513
Domain	Znf_MIZ	ZMIZ1 ZMIZ2	8.57e-04	8	105	2	IPR004181
Domain	Enhancer_polycomb-like_N	JADE2 JADE1	8.57e-04	8	105	2	IPR019542
Domain	C_TYPE_LECTIN_1	SELP FCER2 PKD1 KLRG1	1.07e-03	80	105	4	PS00615
Domain	Lectin_C	SELP FCER2 PKD1 KLRG1	1.29e-03	84	105	4	PF00059
Domain	CLECT	SELP FCER2 PKD1 KLRG1	1.29e-03	84	105	4	SM00034
Domain	C_TYPE_LECTIN_2	SELP FCER2 PKD1 KLRG1	1.35e-03	85	105	4	PS50041
Domain	C-type_lectin-like	SELP FCER2 PKD1 KLRG1	1.41e-03	86	105	4	IPR001304
Domain	Znf_FYVE_PHD	RAG2 KDM5A JADE2 JADE1 ANKIB1	1.45e-03	147	105	5	IPR011011
Domain	F-box-like	FBXW2 FBXL2 FBXO15	1.93e-03	44	105	3	PF12937
Domain	C8	ZAN MUC19	1.99e-03	12	105	2	PF08742
Domain	TIL	ZAN MUC19	1.99e-03	12	105	2	PF01826
Domain	ZF_PHD_2	RAG2 KDM5A JADE2 JADE1	2.03e-03	95	105	4	PS50016
Domain	ZF_PHD_1	RAG2 KDM5A JADE2 JADE1	2.11e-03	96	105	4	PS01359
Domain	-	SELP FCER2 PKD1 KLRG1	2.19e-03	97	105	4	3.10.100.10
Domain	Unchr_dom_Cys-rich	ZAN MUC19	2.35e-03	13	105	2	IPR014853
Domain	C8	ZAN MUC19	2.35e-03	13	105	2	SM00832
Domain	C-type_lectin-like/link	SELP FCER2 PKD1 KLRG1	2.36e-03	99	105	4	IPR016186
Domain	LDLRA_1	MFRP CFI PKD1	2.49e-03	48	105	3	PS01209
Domain	LDLRA_2	MFRP CFI PKD1	2.64e-03	49	105	3	PS50068
Domain	TIL_dom	ZAN MUC19	2.73e-03	14	105	2	IPR002919
Domain	-	MED16 RBBP5 FBXW2 WDR43 WDHD1 NBEAL2 SEMA4A	2.75e-03	333	105	7	2.130.10.10
Domain	WD40/YVTN_repeat-like_dom	MED16 RBBP5 FBXW2 WDR43 WDHD1 NBEAL2 SEMA4A	2.85e-03	335	105	7	IPR015943
Domain	CTDL_fold	SELP FCER2 PKD1 KLRG1	3.12e-03	107	105	4	IPR016187
Domain	FBOX	FBXW2 FBXL2 FBXO15	3.12e-03	52	105	3	SM00256
Domain	WD40	MED16 RBBP5 FBXW2 WDR43 WDHD1 NBEAL2	3.44e-03	259	105	6	PF00400
Domain	VWF_type-D	ZAN MUC19	3.57e-03	16	105	2	IPR001846
Domain	VWFD	ZAN MUC19	3.57e-03	16	105	2	PS51233
Domain	VWD	ZAN MUC19	3.57e-03	16	105	2	SM00216
Domain	VWD	ZAN MUC19	3.57e-03	16	105	2	PF00094
Domain	LRR_6	NLRP9 FBXL2 NLRP13	3.66e-03	55	105	3	PF13516
Domain	WD40	MED16 RBBP5 FBXW2 WDR43 WDHD1 NBEAL2	4.07e-03	268	105	6	SM00320
Domain	WD40_repeat	MED16 RBBP5 FBXW2 WDR43 WDHD1 NBEAL2	4.37e-03	272	105	6	IPR001680
Domain	WD_REPEATS_1	MED16 RBBP5 FBXW2 WDR43 WDHD1 NBEAL2	4.85e-03	278	105	6	PS00678
Domain	WD_REPEATS_2	MED16 RBBP5 FBXW2 WDR43 WDHD1 NBEAL2	4.94e-03	279	105	6	PS50082
Domain	WD_REPEATS_REGION	MED16 RBBP5 FBXW2 WDR43 WDHD1 NBEAL2	4.94e-03	279	105	6	PS50294
Domain	VWC_out	ZAN MUC19	5.03e-03	19	105	2	SM00215
Domain	PLAC	ADAMTS12 ADAMTS6	5.03e-03	19	105	2	PS50900
Domain	PLAC	ADAMTS12 ADAMTS6	5.03e-03	19	105	2	IPR010909
Domain	EGF	SELP ZAN SVEP1 CNTNAP2	5.59e-03	126	105	4	PF00008
Pubmed	Requirement for Runx proteins in IgA class switching acting downstream of TGF-beta 1 and retinoic acid signaling.	RAG2 RUNX2 RUNX3	1.30e-07	4	112	3	20142360
Pubmed	Epidemiological approach to identifying genetic predispositions for atypical hemolytic uremic syndrome.	CFH CFI C4BPA	2.69e-06	9	112	3	20059470
Pubmed	Runx2 (Cbfa1) inhibits Shh signaling in the lower but not upper molars of mouse embryos and prevents the budding of putative successional teeth.	RUNX2 RUNX3 PTCH2	5.26e-06	11	112	3	15668330
Pubmed	NC4 Domain of cartilage-specific collagen IX inhibits complement directly due to attenuation of membrane attack formation and indirectly through binding and enhancing activity of complement inhibitors C4B-binding protein and factor H.	CFH C4BPA	1.03e-05	2	112	2	21659506
Pubmed	Runx3 is required for full activation of regulatory T cells to prevent colitis-associated tumor formation.	RAG2 RUNX3	1.03e-05	2	112	2	21515792
Pubmed	Polycystin-1 regulates skeletogenesis through stimulation of the osteoblast-specific transcription factor RUNX2-II.	RUNX2 PKD1	1.03e-05	2	112	2	18321855
Pubmed	Non-small cell lung cancer cells produce a functional set of complement factor I and its soluble cofactors.	CFI C4BPA	1.03e-05	2	112	2	17548110
Pubmed	Interferon Regulatory Factor-5 in Resident Macrophage Promotes Polycystic Kidney Disease.	IRF5 PKD1	1.03e-05	2	112	2	33490963
Pubmed	Association between vitamin D status and age-related macular degeneration by genetic risk.	CFH CFI	1.03e-05	2	112	2	26312598
Pubmed	Identification of sequence variants influencing immunoglobulin levels.	RUNX2 RUNX3	1.03e-05	2	112	2	28628107
Pubmed	Use of time-resolved FRET to validate crystal structure of complement regulatory complex between C3b and factor H (N terminus).	CFH CFI	1.03e-05	2	112	2	21936007
Pubmed	Genome-wide analyses of human perisylvian cerebral cortical patterning.	PCDH17 CNTNAP2	1.03e-05	2	112	2	17978184
Pubmed	Runx2 activates hepatic stellate cells to promote liver fibrosis via transcriptionally regulating Itgav expression.	RUNX2 ITGAV	1.03e-05	2	112	2	37403784
Pubmed	Cilia-like structures and polycystin-1 in osteoblasts/osteocytes and associated abnormalities in skeletogenesis and Runx2 expression.	RUNX2 PKD1	1.03e-05	2	112	2	16905538
Pubmed	Spatial and temporal expression of Zimp7 and Zimp10 PIAS-like proteins in the developing mouse embryo.	ZMIZ1 ZMIZ2	1.03e-05	2	112	2	18053775
Pubmed	Regulatory components of the alternative complement pathway in endothelial cell cytoplasm, factor H and factor I, are not packaged in Weibel-Palade bodies.	CFH CFI	1.03e-05	2	112	2	25803806
Pubmed	Identification of Two Additional Susceptibility Loci for Inflammatory Bowel Disease in a Chinese Population.	ZMIZ1 TNFSF15	1.03e-05	2	112	2	28456797
Pubmed	Integrin αvβ3 mediates the synergetic regulation of core-binding factor α1 transcriptional activity by gravity and insulin-like growth factor-1 through phosphoinositide 3-kinase signaling.	RUNX2 ITGAV	1.03e-05	2	112	2	25263523
Pubmed	Genome-wide association study of advanced age-related macular degeneration identifies a role of the hepatic lipase gene (LIPC).	CFH RREB1 CFI	1.44e-05	15	112	3	20385826
Pubmed	Genetic influences on the end-stage effector phase of arthritis.	SELP CFH C4BPA	1.77e-05	16	112	3	11489951
Pubmed	Identification and characterization of the potential promoter regions of 1031 kinds of human genes.	MED16 RBBP5 MELTF GARRE1	2.45e-05	52	112	4	11337467
Pubmed	Identification of Jade1, a gene encoding a PHD zinc finger protein, in a gene trap mutagenesis screen for genes involved in anteroposterior axis development.	JADE2 JADE1	3.08e-05	3	112	2	14612400
Pubmed	Tumor-derived semaphorin 4A improves PD-1-blocking antibody efficacy by enhancing CD8+ T cell cytotoxicity and proliferation.	RAG2 SEMA4A	3.08e-05	3	112	2	37205755
Pubmed	Expression of Runx1, -2 and -3 during tooth, palate and craniofacial bone development.	RUNX2 RUNX3	3.08e-05	3	112	2	14516670
Pubmed	Insights into hemolytic uremic syndrome: segregation of three independent predisposition factors in a large, multiple affected pedigree.	CFH CFI	3.08e-05	3	112	2	16386793
Pubmed	Ultrastructures and interactions of complement factors H and I.	CFH CFI	3.08e-05	3	112	2	1401896
Pubmed	TL1A (TNFSF15) regulates the development of chronic colitis by modulating both T-helper 1 and T-helper 17 activation.	RAG2 TNFSF15	3.08e-05	3	112	2	18598698
Pubmed	Wnt/β-Catenin Signaling Exacerbates Keloid Cell Proliferation by Regulating Telomerase.	TERT WNT10A	3.08e-05	3	112	2	27771714
Pubmed	Regulator-dependent mechanisms of C3b processing by factor I allow differentiation of immune responses.	CFH CFI	3.08e-05	3	112	2	28671664
Pubmed	Differential impact of complement mutations on clinical characteristics in atypical hemolytic uremic syndrome.	CFH CFI	3.08e-05	3	112	2	17599974
Pubmed	AML1, AML2, and AML3, the human members of the runt domain gene-family: cDNA structure, expression, and chromosomal localization.	RUNX2 RUNX3	3.08e-05	3	112	2	7835892
Pubmed	Polycystin-1 regulates the stability and ubiquitination of transcription factor Jade-1.	JADE1 PKD1	3.08e-05	3	112	2	23001567
Pubmed	Factor I is required for the development of membranoproliferative glomerulonephritis in factor H-deficient mice.	CFH CFI	3.08e-05	3	112	2	18202746
Pubmed	Factor H, membrane cofactor protein, and factor I mutations in patients with hemolysis, elevated liver enzymes, and low platelet count syndrome.	CFH CFI	3.08e-05	3	112	2	18658028
Pubmed	Genetics of HUS: the impact of MCP, CFH, and IF mutations on clinical presentation, response to treatment, and outcome.	CFH CFI	3.08e-05	3	112	2	16621965
Pubmed	Runx2 and Runx3 differentially regulate articular chondrocytes during surgically induced osteoarthritis development.	RUNX2 RUNX3	3.08e-05	3	112	2	36261443
Pubmed	A novel method for real-time analysis of the complement C3b:FH:FI complex reveals dominant negative CFI variants in age-related macular degeneration.	CFH CFI	3.08e-05	3	112	2	36643920
Pubmed	Genotype-phenotype correlations of low-frequency variants in the complement system in renal disease and age-related macular degeneration.	CFH CFI	3.08e-05	3	112	2	29888403
Pubmed	Acquisition of complement inhibitor serine protease factor I and its cofactors C4b-binding protein and factor H by Prevotella intermedia.	CFH CFI	3.08e-05	3	112	2	22514678
Pubmed	Interactions between human complement components factor H, factor I and C3b.	CFH CFI	3.08e-05	3	112	2	9291131
Pubmed	Studies on the interactions between C-reactive protein and complement proteins.	CFH C4BPA	3.08e-05	3	112	2	17244159
Pubmed	Shared and distinct roles mediated through C-terminal subdomains of acute myeloid leukemia/Runt-related transcription factor molecules in murine development.	RUNX2 RUNX3	3.08e-05	3	112	2	15713794
Pubmed	Genetic regulation of the RUNX transcription factor family has antitumor effects.	RUNX2 RUNX3	3.08e-05	3	112	2	28530640
Pubmed	The novel PIAS-like protein hZimp10 is a transcriptional co-activator of the p53 tumor suppressor.	ZMIZ1 ZMIZ2	3.08e-05	3	112	2	17584785
Pubmed	Identification and comparative analysis of a second runx3 promoter.	RUNX2 RUNX3	3.08e-05	3	112	2	11483356
Pubmed	Dual roles of different redox forms of complement factor H in protecting against age related macular degeneration.	CFH CFI	3.08e-05	3	112	2	30253188
Pubmed	ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.	CFH NEMP1 ITGAV CRELD1 MELTF ADSL CNIH4 RRAGA PIGX RNFT1 TYW1 DSEL PPP6R2 PIGO	3.27e-05	1201	112	14	35696571
Pubmed	BRCA2 mediates centrosome cohesion via an interaction with cytoplasmic dynein.	CFH TTF2 TERT GREB1L	3.53e-05	57	112	4	27433848
Pubmed	Enhanced analysis of the mouse plasma proteome using cysteine-containing tryptic glycopeptides.	CFH CFI TF C4BPA	4.05e-05	59	112	4	17330941
Pubmed	Brn3a regulates neuronal subtype specification in the trigeminal ganglion by promoting Runx expression during sensory differentiation.	MRGPRD RUNX2 RUNX3	5.49e-05	23	112	3	20096094
Pubmed	Genetic disorders in complement (regulating) genes in patients with atypical haemolytic uraemic syndrome (aHUS).	CFH CFI	6.14e-05	4	112	2	20106822
Pubmed	Evolution of the interaction between Runx2 and VDR, two transcription factors involved in osteoblastogenesis.	RUNX2 RUNX3	6.14e-05	4	112	2	20236534
Pubmed	Central Role of Core Binding Factor β2 in Mucosa-Associated Lymphoid Tissue Organogenesis in Mouse.	RUNX2 RUNX3	6.14e-05	4	112	2	26001080
Pubmed	Outside-in integrin signalling regulates haematopoietic stem cell function via Periostin-Itgav axis.	RAG2 ITGAV	6.14e-05	4	112	2	27905395
Pubmed	Native, amyloid fibrils and beta-oligomers of the C-terminal domain of human prion protein display differential activation of complement and bind C1q, factor H and C4b-binding protein directly.	CFH C4BPA	6.14e-05	4	112	2	18406463
Pubmed	The Runx-PU.1 pathway preserves normal and AML/ETO9a leukemic stem cells.	RUNX2 RUNX3	6.14e-05	4	112	2	25185713
Pubmed	Mechanosensor polycystin-1 potentiates differentiation of human osteoblastic cells by upregulating Runx2 expression via induction of JAK2/STAT3 signaling axis.	RUNX2 PKD1	6.14e-05	4	112	2	27699453
Pubmed	Differential requirements for Runx proteins in CD4 repression and epigenetic silencing during T lymphocyte development.	RUNX2 RUNX3	6.14e-05	4	112	2	12464175
Pubmed	Isolation of PEBP2 alpha B cDNA representing the mouse homolog of human acute myeloid leukemia gene, AML1.	RUNX2 RUNX3	6.14e-05	4	112	2	8437866
Pubmed	Integrin αvβ3 and CD44 pathways in metastatic prostate cancer cells support osteoclastogenesis via a Runx2/Smad 5/receptor activator of NF-κB ligand signaling axis.	RUNX2 ITGAV	6.14e-05	4	112	2	22966907
Pubmed	Inflammation-driven colon neoplasmatogenesis in uPA-deficient mice is associated with an increased expression of Runx transcriptional regulators.	RUNX2 RUNX3	6.14e-05	4	112	2	29107070
Pubmed	A WW domain-containing yes-associated protein (YAP) is a novel transcriptional co-activator.	RUNX2 RUNX3	6.14e-05	4	112	2	10228168
Pubmed	T Cells Prevent Hemorrhagic Transformation in Ischemic Stroke by P-Selectin Binding.	SELP RAG2	6.14e-05	4	112	2	29903733
Pubmed	Loss of osteoblast Runx3 produces severe congenital osteopenia.	RUNX2 RUNX3	6.14e-05	4	112	2	25605327
Pubmed	Runx3 negatively regulates Osterix expression in dental pulp cells.	RUNX2 RUNX3	6.14e-05	4	112	2	17352693
Pubmed	New functional and structural insights from updated mutational databases for complement factor H, Factor I, membrane cofactor protein and C3.	CFH CFI	6.14e-05	4	112	2	25188723
Pubmed	The vitronectin receptor and its associated CD47 molecule mediates proinflammatory cytokine synthesis in human monocytes by interaction with soluble CD23.	ITGAV FCER2	6.14e-05	4	112	2	10037797
Pubmed	Dendritic cells suppress IgE production in B cells.	RAG2 FCER2	6.14e-05	4	112	2	17208926
Pubmed	Inhibition of c3 convertase activity by hepatitis C virus as an additional lesion in the regulation of complement components.	CFH CFI	6.14e-05	4	112	2	24983375
Pubmed	Telomerase accelerates osteogenesis of bone marrow stromal stem cells by upregulation of CBFA1, osterix, and osteocalcin.	RUNX2 TERT	6.14e-05	4	112	2	12674332
Pubmed	Rare Genetic Variants Associated With Development of Age-Related Macular Degeneration.	CFH CFI	6.14e-05	4	112	2	26767664
Pubmed	Chromatin remodeling: recruitment of histone demethylase RBP2 by Mad1 for transcriptional repression of a Myc target gene, telomerase reverse transcriptase.	KDM5A TERT	6.14e-05	4	112	2	19762557
Pubmed	Dual color FISH on CBF primary acute myeloid leukemia.	RUNX2 RUNX3	6.14e-05	4	112	2	20306685
Pubmed	KLRG1+ Effector CD8+ T Cells Lose KLRG1, Differentiate into All Memory T Cell Lineages, and Convey Enhanced Protective Immunity.	RAG2 KLRG1	6.14e-05	4	112	2	29625895
Pubmed	Ribonucleome analysis identified enzyme genes responsible for wybutosine synthesis.	TYW1 TRMT12	6.14e-05	4	112	2	17150819
Pubmed	Mutagenesis of the Runt domain defines two energetic hot spots for heterodimerization with the core binding factor beta subunit.	RUNX2 RUNX3	6.14e-05	4	112	2	12807883
Pubmed	Estrogen-regulated feedback loop limits the efficacy of estrogen receptor-targeted breast cancer therapy.	RAG2 RGSL1 CFI TTC3 DENND4C MELTF NLRP9 PKD1 FBXL2 LIPI	7.77e-05	686	112	10	29987050
Pubmed	Molecular cloning of rat and mouse membrane cofactor protein (MCP, CD46): preferential expression in testis and close linkage between the mouse Mcp and Cr2 genes on distal chromosome 1.	CFH C4BPA	1.02e-04	5	112	2	9799332
Pubmed	NK cell maturation and peripheral homeostasis is associated with KLRG1 up-regulation.	RAG2 KLRG1	1.02e-04	5	112	2	17404256
Pubmed	Metalloproteinase Adamts16 Is Required for Proper Closure of the Optic Fissure.	ADAMTS12 ADAMTS6	1.02e-04	5	112	2	29625437
Pubmed	The novel PIAS-like protein hZimp10 enhances Smad transcriptional activity.	ZMIZ1 ZMIZ2	1.02e-04	5	112	2	16777850
Pubmed	Oncogenic Runx1-Myc axis in p53-deficient thymic lymphoma.	RUNX2 RUNX3	1.02e-04	5	112	2	35114276
Pubmed	PTHrP prevents chondrocyte premature hypertrophy by inducing cyclin-D1-dependent Runx2 and Runx3 phosphorylation, ubiquitylation and proteasomal degradation.	RUNX2 RUNX3	1.02e-04	5	112	2	19351720
Pubmed	Tumor cell integrin β4 and tumor stroma E-/P-selectin cooperatively regulate tumor growth in vivo.	SELP RAG2	1.02e-04	5	112	2	36932441
Pubmed	Runx3 is required for oncogenic Myc upregulation in p53-deficient osteosarcoma.	RUNX2 RUNX3	1.02e-04	5	112	2	34803166
Pubmed	Transcriptional regulation of osteopontin gene in vivo by PEBP2alphaA/CBFA1 and ETS1 in the skeletal tissues.	RUNX2 RUNX3	1.02e-04	5	112	2	9794229
Pubmed	Sexually dimorphic gene expression of the Zimp7 and Zimp10 genes in embryonic gonads.	ZMIZ1 ZMIZ2	1.02e-04	5	112	2	19931425
Pubmed	Foxp3 controls regulatory T-cell function by interacting with AML1/Runx1.	RUNX2 RUNX3	1.02e-04	5	112	2	17377532
Pubmed	Interplay between SOX7 and RUNX1 regulates hemogenic endothelial fate in the yolk sac.	RUNX2 RUNX3	1.02e-04	5	112	2	27802172
Pubmed	Basophils play a critical role in the development of IgE-mediated chronic allergic inflammation independently of T cells and mast cells.	RAG2 FCER2	1.02e-04	5	112	2	16111637
Pubmed	Kif3a deficiency reverses the skeletal abnormalities in Pkd1 deficient mice by restoring the balance between osteogenesis and adipogenesis.	RUNX2 PKD1	1.02e-04	5	112	2	21151991
Pubmed	TASL is the SLC15A4-associated adaptor for IRF5 activation by TLR7-9.	IRF5 RRAGA	1.02e-04	5	112	2	32433612
Pubmed	A systems-wide screen identifies substrates of the SCFβTrCP ubiquitin ligase.	RBM10 FBXW2 DENND4C TRIM32 PIGX GARRE1	1.10e-04	232	112	6	25515538
Pubmed	Selectin-deficiency reduces the number of spontaneous metastases in a xenograft model of human breast cancer.	SELP RAG2	1.53e-04	6	112	2	22366582
Pubmed	Runx1 and Cbfβ regulate the development of Flt3+ dendritic cell progenitors and restrict myeloproliferative disorder.	RUNX2 RUNX3	1.53e-04	6	112	2	24677539
Pubmed	Inflammatory responses induce an identity crisis of alveolar macrophages, leading to pulmonary alveolar proteinosis.	RAG2 RUNX3	1.53e-04	6	112	2	28916727
Pubmed	Transcription factors Runx1 to 3 are expressed in the lacrimal gland epithelium and are involved in regulation of gland morphogenesis and regeneration.	RUNX2 RUNX3	1.53e-04	6	112	2	23532528
Pubmed	A novel role for protein inhibitor of activated STAT (PIAS) proteins in modulating the activity of Zimp7, a novel PIAS-like protein, in androgen receptor-mediated transcription.	ZMIZ1 ZMIZ2	1.53e-04	6	112	2	20159969
Pubmed	The essential requirement for Runx1 in the development of the sternum.	RUNX2 RUNX3	1.53e-04	6	112	2	20152828
Pubmed	Zfp521 controls bone mass by HDAC3-dependent attenuation of Runx2 activity.	RUNX2 RUNX3	1.53e-04	6	112	2	21173110
Cytoband	1q32	CFH RBBP5 C4BPA	2.40e-04	49	112	3	1q32
GeneFamily	Hyalectan proteoglycans\|V-set domain containing\|Sushi domain containing\|C-type lectin domain containing	SELP CFH SVEP1 C4BPA CSMD1	2.69e-06	57	70	5	1179
GeneFamily	Transferrins	TF MELTF	4.42e-05	3	70	2	908
GeneFamily	Zinc fingers MIZ-type	ZMIZ1 ZMIZ2	3.06e-04	7	70	2	85
GeneFamily	WD repeat domain containing	MED16 RBBP5 FBXW2 WDR43 WDHD1 NBEAL2	5.28e-04	262	70	6	362
GeneFamily	Hyalectan proteoglycans\|V-set domain containing\|Sushi domain containing\|C-type lectin domain containing	SELP FCER2 PKD1	5.33e-04	41	70	3	1298
GeneFamily	Dyneins, axonemal	DNAH7 DNAH17	1.94e-03	17	70	2	536
GeneFamily	ADAM metallopeptidases with thrombospondin type 1 motif	ADAMTS12 ADAMTS6	2.42e-03	19	70	2	50
GeneFamily	Zinc fingers RANBP2-type \|RNA binding motif containing	RBM10 CAPN15	2.96e-03	21	70	2	89
GeneFamily	Glycosyl transferases group 1 domain containing\|Phosphatidylinositol glycan anchor biosynthesis	PIGX PIGO	2.96e-03	21	70	2	680
GeneFamily	NLR family	NLRP9 NLRP13	4.18e-03	25	70	2	666
GeneFamily	Pyrin domain containing\|Pyrin and HIN domain family	NLRP9 NLRP13	4.18e-03	25	70	2	994
GeneFamily	PHD finger proteins	KDM5A JADE2 JADE1	5.13e-03	90	70	3	88
GeneFamily	Complement system\|Sushi domain containing	CFH CFI	8.55e-03	36	70	2	492
Coexpression	HE_LIM_SUN_FETAL_LUNG_C5_CD5_POS_CCL22_NEG_MATURE_B_CELL	PDE7A IRF5 RUNX3 FCER2 ADAMTS6 WNT10A SEMA4A	5.86e-06	160	112	7	M45779
Coexpression	GSE45365_HEALTHY_VS_MCMV_INFECTION_CD11B_DC_IFNAR_KO_UP	JADE2 ZMIZ1 CHIC1 CNTNAP2 DSEL FAM118A CAPN15	2.05e-05	194	112	7	M9980
Coexpression	GSE2405_0H_VS_12H_A_PHAGOCYTOPHILUM_STIM_NEUTROPHIL_DN	MORC1 RAG2 TTF2 FOCAD WDHD1 TRIM32 TRMT12	2.42e-05	199	112	7	M6203
CoexpressionAtlas	alpha beta T cells, T.8Mem.Sp.OT1.d45.VSVOva, CD8+ CD45.1+, Spleen, avg-3	PDE7A JADE2 RUNX2 RUNX3 ZNF831 DENND4C NBEAL2 SEMA4A FBXL2 KLRG1	2.04e-05	383	105	10	GSM538403_500
ToppCell	3'-Adult-SmallIntestine-Hematopoietic-Plasma_cells-IgA_plasma_cell\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	JADE2 PIWIL1 FPGT RUNX2 CHIC1 FCER2 WNT10A	3.31e-07	177	112	7	b326376e879afef579b1b7094d756aaff0de270b
ToppCell	3'-Adult-SmallIntestine-Hematopoietic-Plasma_cells\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	JADE2 PIWIL1 FPGT RUNX2 CHIC1 FCER2 WNT10A	3.31e-07	177	112	7	393882f1bf7658a17e10a771b803339f16fb2e69
ToppCell	Endothelial-endothelial_cell_of_artery\|World / Lineage, Cell type, age group and donor	SELP NPDC1 PCDH17 LDB2 ADAMTS6 CSMD1 GARRE1	5.16e-07	189	112	7	fdd89c71113ac99b7c800c6def8888e512ff1128
ToppCell	LPS-IL1RA-Endothelial-Endothelial-Vein\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	SELP NPDC1 GRIN2B PCDH17 LDB2 CLDN11 ADAMTS6	5.73e-07	192	112	7	717f3d3bbee4d0f64ba1341ee2b00a407ba1e0f3
ToppCell	LPS-IL1RA+antiTNF-Endothelial-Endothelial-Vein\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	SELP NPDC1 GRIN2B PCDH17 LDB2 CLDN11 ADAMTS6	5.94e-07	193	112	7	7261c1ce30c796b61c6ec58e64a051baa24732ff
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	CFH RUNX2 PTGIR SVEP1 LDB2 ADAMTS12 PTCH2	6.15e-07	194	112	7	81713e0409e8be695ba5dfdc67a997b33435dd9e
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	CFH RUNX2 PTGIR SVEP1 LDB2 ADAMTS12 PTCH2	6.15e-07	194	112	7	627cffe2d448e74fc5df92e74e5b922a73304137
ToppCell	LPS-antiTNF-Epithelial_alveolar-Mes-like\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	AKNAD1 GRIN2B TF PTGIR LHFPL1 SVEP1	1.15e-06	134	112	6	64979e1a056b7406e1be39c5ebe2f8d731ac3c17
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-proliferative_fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	CFH PTGIR SVEP1 LDB2 ADAMTS12 PTCH2	3.47e-06	162	112	6	bfaeff19bb56598fdc8c82be71d51787cf13928f
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-proliferative_fibroblast\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	CFH PTGIR SVEP1 LDB2 ADAMTS12 DMRT3	4.42e-06	169	112	6	a84490724a206c9bbb145f7ce08613f91d100ac4
ToppCell	Fetal_29-31_weeks-Endothelial-endothelial_cell_of_artery\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	SELP MUC19 GRIN2B PCDH17 LDB2 ADAMTS6	5.77e-06	177	112	6	5ff8dcfb030312126695d53a026d2e104a401b83
ToppCell	droplet-Spleen-nan-18m-Lymphocytic-mature_NK_T_cell\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RUNX2 RUNX3 DENND4C CD163L1 NBEAL2 SEMA4A	5.77e-06	177	112	6	6561794ae3b14b5279b249eb5e93b80ef15ed82c
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ZAN GRIN2B ODAD2 MELTF DGKK CSMD1	7.20e-06	184	112	6	2cbed6462fea2622871bb7e49b0df3d984239281
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ZAN GRIN2B ODAD2 MELTF DGKK CSMD1	7.20e-06	184	112	6	ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ZAN GRIN2B ODAD2 MELTF DGKK CSMD1	7.20e-06	184	112	6	2b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell	COVID-19-Endothelial_cells-Arterial_endothelial_cells\|COVID-19 / group, cell type (main and fine annotations)	SELP NPDC1 PCDH17 LDB2 CSMD1 GARRE1	7.20e-06	184	112	6	0f19494789f38ab1a420545e15e748ca7eb345c3
ToppCell	Control-Endothelial-Endothelial-Vein\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	SELP GRIN2B PCDH17 LDB2 CLDN11 ADAMTS6	7.66e-06	186	112	6	92092f11ecce22c14f244e42c499af0822977e6f
ToppCell	Control-Endothelial_cells-Arterial_endothelial_cells\|Control / group, cell type (main and fine annotations)	SELP NPDC1 PCDH17 LDB2 CSMD1 GARRE1	7.90e-06	187	112	6	81affaab3fe3e1daea45ada6445e906ddd33950e
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	CFH RUNX2 PTGIR SVEP1 LDB2 ADAMTS12	8.39e-06	189	112	6	71397e993a77d70b2eeede240bdfc7660b558987
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	CFH RUNX2 PTGIR SVEP1 LDB2 ADAMTS12	8.39e-06	189	112	6	4eea4759520c312bd17a681034d8074e47093d2b
ToppCell	nucseq-Endothelial-Endothelial_Vascular-Endothelial_large_blood_vessel-AEC\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	SELP NPDC1 PCDH17 LDB2 CSMD1 GARRE1	8.91e-06	191	112	6	50601ef0a5a8f2c2120922989e08e85bf2d9b4ab
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	CFH RUNX2 PTGIR SVEP1 LDB2 ADAMTS12	8.91e-06	191	112	6	39092a0aff8097617820c59f5fea9ee2bb4f63a2
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	CFH RUNX2 PTGIR SVEP1 LDB2 ADAMTS12	8.91e-06	191	112	6	ee5f1b1c59029c46cbb1a00935c03b9317bb9da9
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	CFH RUNX2 PTGIR SVEP1 LDB2 ADAMTS12	9.18e-06	192	112	6	bc84b9ce01b4d826a682842ab8a395dac9b91183
ToppCell	LPS_only-Endothelial-Endothelial-Vein\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	SELP NPDC1 PCDH17 LDB2 CLDN11 ADAMTS6	9.18e-06	192	112	6	52acaecd3703166f5ce3b328aff7c82bd142fee4
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	CFH RUNX2 PTGIR SVEP1 LDB2 ADAMTS12	9.18e-06	192	112	6	0ab1176cfbb0de8dd1f22c6e2c41265cf6c10ee1
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	CFH PTGIR SVEP1 LDB2 ADAMTS12 PTCH2	9.74e-06	194	112	6	cf0244a29934e515446ac917d3c30672b460fb04
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	CFH RUNX2 PTGIR SVEP1 LDB2 ADAMTS12	9.74e-06	194	112	6	e03ba6caed59fa64d4d9b042593469d4a6a3dc10
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	CFH PTGIR SVEP1 LDB2 ADAMTS12 PTCH2	9.74e-06	194	112	6	ba7f971fb9a19423602da60770f23d9fead4a451
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	CFH PTGIR SVEP1 LDB2 ADAMTS12 PTCH2	1.00e-05	195	112	6	3c3703f092b6fc1b7333426fb5e2823bfb74bb57
ToppCell	5'-Adult-LargeIntestine-Endothelial-blood_vessel_EC-Mature_venous_EC\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SELP NPDC1 CFI PCDH17 LDB2 GARRE1	1.06e-05	197	112	6	87eda06344498dc66cac292cf89746dc90b5cf67
ToppCell	distal-Endothelial-Vein-1\|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	SELP NPDC1 CFI PCDH17 LDB2 CLDN11	1.06e-05	197	112	6	3d71c93da4b88ebbd58e68ed3dbf610d4bcfc4f5
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	CFH RUNX2 PTGIR SVEP1 LDB2 ADAMTS12	1.06e-05	197	112	6	ae0435f4b4a9cdedb1c201fc56921048390097bf
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	CFH RUNX2 PTGIR SVEP1 LDB2 ADAMTS12	1.06e-05	197	112	6	37f6b6f2809b952382eaebb642b0aad6371f4251
ToppCell	Somatosensory_Cortex_(S1)-Neuronal\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	GRIN2B TTC3 FOCAD PKD1 CNTNAP2 CSMD1	1.09e-05	198	112	6	c01091ef18e096d792ea2a7a715764a5b215355f
ToppCell	Sepsis-ICU-SEP-Lymphocyte-T/NK-MAIT\|ICU-SEP / Disease, condition lineage and cell class	CFH PIWIL1 DSEL FBXL2 KLRG1 TRMT12	1.13e-05	199	112	6	2f10622319c6146dfed8cfe3844180c1e1d56e94
ToppCell	Parenchyma_COVID-19-Endothelial-TX-Artery\|Parenchyma_COVID-19 / Sample group, Lineage and Cell type	SELP NPDC1 PCDH17 LDB2 ADAMTS6 GARRE1	1.16e-05	200	112	6	34b279804475ea58fbb052b96f44128c082627a9
ToppCell	Lung_Parenchyma-Severe-Endothelial-Endothelial-Artery\|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)	SELP NPDC1 PCDH17 LDB2 ADAMTS6 GARRE1	1.16e-05	200	112	6	8552cc7a439449b30b59760c3e8667217b9852b5
ToppCell	Parenchyma_COVID-19-Endothelial-TX\|Parenchyma_COVID-19 / Sample group, Lineage and Cell type	SELP NPDC1 PCDH17 LDB2 ADAMTS6 GARRE1	1.16e-05	200	112	6	abcbd5a156aa4fd51d284441388975c81c0b88ae
ToppCell	distal-3-Endothelial-Vein\|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	SELP NPDC1 CFI PCDH17 LDB2 CLDN11	1.16e-05	200	112	6	3a5c85bad2e7a9ecf55d90acb04178a343b3f5fd
ToppCell	Lung_Parenchyma-Severe-Endothelial\|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)	SELP NPDC1 PCDH17 LDB2 ADAMTS6 GARRE1	1.16e-05	200	112	6	d9d0ffa18e5b4647966e19ad9830cbba6120677e
ToppCell	Lung_Parenchyma-Severe-Endothelial-Endothelial-Endothelial-1\|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)	SELP NPDC1 PCDH17 LDB2 ADAMTS6 GARRE1	1.16e-05	200	112	6	27507c4b41d45c7cc50e4993169c0302be22ee34
ToppCell	Lung_Parenchyma-Severe-Endothelial-Endothelial\|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)	SELP NPDC1 PCDH17 LDB2 ADAMTS6 GARRE1	1.16e-05	200	112	6	e9d5ba140cabae11c437012d519b85f5412dcc94
ToppCell	Parenchyma_COVID-19-Endothelial-TX-Endothelial-1\|Parenchyma_COVID-19 / Sample group, Lineage and Cell type	SELP NPDC1 PCDH17 LDB2 ADAMTS6 GARRE1	1.16e-05	200	112	6	b65fb8d378abd91cdabf5faac5f4b90d527f8c44
ToppCell	Lung_Parenchyma-Severe-Endothelial-Endothelial-Endothelial-1-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	SELP NPDC1 PCDH17 LDB2 ADAMTS6 GARRE1	1.16e-05	200	112	6	2cb6e35add34b9dc564ebcf5d3cbc761325ca9f4
ToppCell	Lung_Parenchyma-Severe-Endothelial-Endothelial-Artery-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	SELP NPDC1 PCDH17 LDB2 ADAMTS6 GARRE1	1.16e-05	200	112	6	45c08f1befe78553bbadcc2fcffb6138306638f3
ToppCell	Hippocampus-Neuronal-Excitatory-eN1(Slc17a7)-eN1_2-Pvrl3-Excitatory_Neuron.Slc17a7.Pvrl3-Nos1_(CA3_Principal_cells)\|Hippocampus / BrainAtlas - Mouse McCarroll V32	MORC1 NPDC1 LHFPL1 PRDM8 LIPI	1.81e-05	128	112	5	9128b633879d21de2ebe651384cfec6d2c3c2932
ToppCell	PND07-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK-ILC\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	RUNX3 PTGIR CD163L1 SEMA4A KLRG1	3.19e-05	144	112	5	46177f0d6117e701bda86a99ac2a1b0e7ed66177
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-proliferative_fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	SVEP1 LDB2 ADAMTS12 PRDM8 LIPI	3.30e-05	145	112	5	051d964ff6bdc12ba3f0459d3e6ab16fa9507b0b
ToppCell	Healthy-B_cell\|World / disease group, cell group and cell class	JADE2 ZNF831 FCER2 CNTNAP2 KLRG1	3.41e-05	146	112	5	588359d3df6ad7090b7fa6c7f8d29cc1717e7f4f
ToppCell	Hippocampus-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)\|Hippocampus / BrainAtlas - Mouse McCarroll V32	TERT PRDM8 ZNF296 CD163L1	4.28e-05	77	112	4	a799ccdb84014e978d9fbccf3d2fee8fbeac7b0c
ToppCell	Hippocampus-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)-Calb2\|Hippocampus / BrainAtlas - Mouse McCarroll V32	MORC1 TERT CD163L1 PTCH2	4.73e-05	79	112	4	03c5af851b53800eced1c74e9da374c71092bcd4
ToppCell	E16.5-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK-NK-NK_mature\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	RUNX2 RUNX3 PTCH2 SEMA4A KLRG1	5.27e-05	160	112	5	b2d8940ea8c068273b7da1589d3d6ae5110d8209
ToppCell	facs-Marrow-B-cells-24m-Lymphocytic-precursor_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MUC19 GRIN2B ODAD2 SVEP1 CNTNAP2	5.27e-05	160	112	5	c381ec6be8cf887861cc18f831a20db42f953fe1
ToppCell	E16.5-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	RUNX2 RUNX3 PTCH2 SEMA4A KLRG1	5.27e-05	160	112	5	9caab1bb63c7e66c44783852ee75b16bb40fa594
ToppCell	facs-Marrow-B-cells-24m-Lymphocytic-pre_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MUC19 GRIN2B ODAD2 SVEP1 CNTNAP2	5.27e-05	160	112	5	25c8f3d2a6d14ff0ca0b965fce89d3ff22f40585
ToppCell	E16.5-Immune-Immune_Lymphocytic_T/NK\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	RUNX2 RUNX3 PTCH2 SEMA4A KLRG1	5.27e-05	160	112	5	229841be7b984a00a301cd5d88c11226a90d8a88
ToppCell	E16.5-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK-NK\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	RUNX2 RUNX3 PTCH2 SEMA4A KLRG1	5.27e-05	160	112	5	99c9ae2041445539fada842e1af01368669bfca0
ToppCell	droplet-Liver-LIVER_HEPATOCYTES-30m-Lymphocytic-NK/T\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RUNX3 ZNF831 PRDM8 CD163L1 KLRG1	5.43e-05	161	112	5	140b3c7077947c541cff54f6754e2df968345f4d
ToppCell	droplet-Liver-LIVER_HEPATOCYTES-30m-Lymphocytic-NK_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RUNX3 ZNF831 PRDM8 CD163L1 KLRG1	5.59e-05	162	112	5	16f9fbcaa0093ffc5a2a5e32db6040e2cb519d47
ToppCell	PND10-Immune-Immune_Myeloid-DC-cDC2-cDC2_prolif\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	IRF5 RUNX3 WDHD1 CD163L1 SEMA4A	5.76e-05	163	112	5	7af3d3ae7e0de733a18d0486c7ffbb5a7ef7230a
ToppCell	Fetal_29-31_weeks-Endothelial-endothelial_cell_of_vein-D088\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	SELP NPDC1 PCDH17 LDB2 ADAMTS6	6.28e-05	166	112	5	f7926ee266dcbf10df375cd921f1db5a2fa604f8
ToppCell	TCGA-Stomach-Primary_Tumor-Stomach_Adenocarcinoma-Stomach_Adenocarcinoma_-_Diffuse-3\|TCGA-Stomach / Sample_Type by Project: Shred V9	SELP CFH SVEP1 PTCH2 KLRG1	6.46e-05	167	112	5	d2230c894ccf9dbba9196e079ae81f384d43da63
ToppCell	390C-Myeloid-Macrophage-SPP1+_Macrophage\|Macrophage / Donor, Lineage, Cell class and subclass (all cells)	PDE7A NPDC1 MELTF CD163L1 ZNF579	6.65e-05	168	112	5	8459d0a1bf6d4b5c83001097331f8b78fceb9305
ToppCell	Adult-Endothelial-endothelial_cell_of_artery-D231\|Adult / Lineage, Cell type, age group and donor	SELP NPDC1 GRIN2B LDB2 ADAMTS6	6.65e-05	168	112	5	aca34c51758c65925ad24110294a72b2dea6db72
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-kidney_interstitial_fibroblast_5\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	CFH RUNX2 SVEP1 LDB2 ADAMTS12	6.65e-05	168	112	5	d19a115365c5415e51c039718d7669de788fcf33
ToppCell	356C-Lymphocytic-CD4_T-cell-Treg_cell_1\|356C / Donor, Lineage, Cell class and subclass (all cells)	KIF27 NPDC1 ZNF831 WNT10A FAM118A	7.63e-05	173	112	5	e3cb7c8c09f937da6b8d673e9adfec5d94a15548
ToppCell	367C-Lymphocytic-CD4_T-cell-CD4+_Effector_T_cell-1\|CD4_T-cell / Donor, Lineage, Cell class and subclass (all cells)	ZNF296 ADAMTS6 SEMA4A DSEL KLRG1	7.63e-05	173	112	5	5d3c917e4d0de3158550a8ab2006ddfa87159ffa
ToppCell	PND14-Immune-Immune_Myeloid-DC-cDC1-cDC1_prolif\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CFH IRF5 RUNX3 ANKIB1 DSEL	7.84e-05	174	112	5	09b091e24317c3f7bac043f04762a533e30793de
ToppCell	10x5'-blood-Lymphocytic_Invariant-Inducer-like\|blood / Manually curated celltypes from each tissue	CFH RUNX2 DNAH7 TRBV6-1 KLRG1	7.84e-05	174	112	5	51be6f29308c01593978cbee92114151a5916c9c
ToppCell	Adult-Endothelial-endothelial_cell_of_vein-D231\|Adult / Lineage, Cell type, age group and donor	SELP NPDC1 PCDH17 LDB2 ADAMTS6	7.84e-05	174	112	5	2dd647c4fdf99fd1f7b838efef01baf2cbc3446d
ToppCell	10x5'-blood-Lymphocytic_Invariant-Inducer-like-MAIT\|blood / Manually curated celltypes from each tissue	CFH RUNX2 DNAH7 TRBV6-1 KLRG1	8.06e-05	175	112	5	b4e4b66e89f79999768a6192c8404cb2465f920b
ToppCell	facs-Marrow-B-cells-24m\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MUC19 GRIN2B FCER2 CNTNAP2 CSMD1	8.06e-05	175	112	5	887e75fc90e59a6394d62f3c048a9cfdf6707725
ToppCell	AT1-AT2_cells-IPF_04\|World / lung cells shred on cell class, cell subclass, sample id	RGSL1 PIWIL1 ITGAV CNTNAP2 C4BPA	8.28e-05	176	112	5	f86832cfeff5b3cfffe4455c1b96a1420d48ba1e
ToppCell	3'-Distal_airway-Endothelial-Blood_vessel_EC-vein_endothelial_cell-EC_venous_systemic-EC_venous_systemic_L.2.2.0.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SELP CFI PCDH17 LDB2 FOCAD	8.50e-05	177	112	5	1921226196b2ab7919d9f843e60d9f4bd9ec9c57
ToppCell	TCGA-Ovary-Primary_Tumor-Ovarian_Carcinoma-Serous_Cystadenocarcinoma-6\|TCGA-Ovary / Sample_Type by Project: Shred V9	PTGIR SVEP1 LDB2 ADAMTS12 PRDM8	8.73e-05	178	112	5	142879e9393e721f9b05a6bb46995c9d6d713c95
ToppCell	Endothelial-A-IPF_04\|World / lung cells shred on cell class, cell subclass, sample id	SELP PCDH17 LDB2 CLDN11 GARRE1	8.73e-05	178	112	5	2f2602b9305d55f25afa9861dd6c6347ae179337
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-kidney_interstitial_fibroblast_5\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	CFH PTGIR SVEP1 LDB2 ADAMTS12	8.73e-05	178	112	5	78a0c6340001a77f5b2d890b6263f574af2e72da
ToppCell	3'-Child09-12-SmallIntestine-Hematopoietic-T_cells-MAIT_cell\|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	PDE7A RUNX2 ZNF831 FAM86C1P KLRG1	8.73e-05	178	112	5	0290868dc990878eac5c182fe64968333bc52450
ToppCell	3'-GW_trimst-2-SmallIntestine-Mesenchymal-mesothelial_cell\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	MORC1 CFH CFI WNT10A PSAPL1	8.96e-05	179	112	5	056df2aaff750e0e283e7da78fcc3c90c366aac0
ToppCell	3'-GW_trimst-2-SmallIntestine-Mesenchymal-mesothelial_cell-Mesothelium\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	MORC1 CFH CFI WNT10A PSAPL1	8.96e-05	179	112	5	f5f3945ef3b9efc5921a71fd51deeb2c80f0ce11
ToppCell	droplet-Lung-nan-18m-Lymphocytic-T_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MORC1 RUNX3 ZNF831 DENND4C CD163L1	8.96e-05	179	112	5	8ebd0c7ac99ac8194fa1a2aac88a893739a97725
ToppCell	droplet-Lung-nan-18m-Lymphocytic-Ly6g5b+_T\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MORC1 RUNX3 ZNF831 DENND4C CD163L1	9.20e-05	180	112	5	81c7086399256260e59424b7410feec514ce8027
ToppCell	Endothelial-A-HP_01\|World / lung cells shred on cell class, cell subclass, sample id	SELP NPDC1 PCDH17 LDB2 CLDN11	9.20e-05	180	112	5	4c3376169770ee9f9283daae44c17f35e46bfd19
ToppCell	droplet-Limb_Muscle-Pre-Sort-18m-Lymphocytic-T_cell\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PDE7A RUNX3 PTGIR USP3 KLRG1	9.44e-05	181	112	5	8a8061725e718c89a4c751a415120c5312acc757
ToppCell	5'-GW_trimst-2-LargeIntestine-Endothelial-blood_vessel_EC-Fetal_venous_EC\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SELP ZAN NPDC1 CFI LDB2	9.69e-05	182	112	5	d0e3663f7d39f22a3ebd7fde56ab3504773598f4
ToppCell	3'-Adult-SmallIntestine-Endothelial-blood_vessel_EC\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CFI PCDH17 LDB2 ADAMTS6 GARRE1	9.94e-05	183	112	5	858682df5592c6856487487a7baabd6e60e63a38
ToppCell	3'_v3-bone_marrow-Lymphocytic_T_CD4/8-lo\|bone_marrow / Manually curated celltypes from each tissue	RUNX3 ZNF831 TRBV6-1 FAM118A KLRG1	9.94e-05	183	112	5	2fb78622adc170dd3301e251418337523de50faf
ToppCell	5'-Adult-LymphNode-Endothelial-blood_vessel_EC-Mature_venous_EC\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SELP NPDC1 CFI PCDH17 LDB2	9.94e-05	183	112	5	a644258ba90acc62d571623e429d72ffc4b69203
ToppCell	3'-Adult-SmallIntestine-Endothelial\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CFI PCDH17 LDB2 ADAMTS6 GARRE1	9.94e-05	183	112	5	f8212bf8a8b8312434ae030261c558c147f61747
ToppCell	Fetal_29-31_weeks-Endothelial-endothelial_cell_of_vein-D150\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	SELP GRIN2B PCDH17 LDB2 ADAMTS6	9.94e-05	183	112	5	c1297d8eddfc7132e84ceef14f01b6281f9d0f6a
ToppCell	3'_v3-bone_marrow-Lymphocytic_T_CD4/8-lo-Tgd_CRTAM\|bone_marrow / Manually curated celltypes from each tissue	RUNX3 ZNF831 TRBV6-1 FAM118A KLRG1	9.94e-05	183	112	5	37db007cc65005bffc18a5fda7f454a57c9fb0a9
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-kidney_interstitial_fibroblast_5\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	CFH PTGIR SVEP1 LDB2 ADAMTS12	1.02e-04	184	112	5	c5436a8e45f471b8d1301abbe9c7879204537f52
ToppCell	Smart-seq2-tissue-resident_(Smart-seq2)-myeloid-myeloid_granulocytic-neutrophil\|tissue-resident_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	MUC19 CFI TF NBEAL2 C4BPA	1.02e-04	184	112	5	7ecdf2645e9378cf2f5ce4557f2cf100e6f184ba
ToppCell	PCW_10-12-Endothelial-Endothelial_mature-endo_arterial_(9)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	CFH MUC19 NPDC1 GRIN2B PCDH17	1.02e-04	184	112	5	a809b0fa52df8a159f60f87eefcef61220af5e34
ToppCell	facs-Thymus-Flowthrough-3m-Lymphocytic-DN_to_DP_transition_(most_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MORC1 RAG2 OSTM1 KDM5A USP3	1.05e-04	185	112	5	dc59b8dc459a3c444c9634a0d438cbef54c40036
ToppCell	COVID-19-Endothelial_cells-Systemic_venous_endothelial_cells\|COVID-19 / group, cell type (main and fine annotations)	SELP NPDC1 PCDH17 LDB2 GARRE1	1.05e-04	185	112	5	f5e14181f45c37d13ee9e017a4c8bc248c353676
ToppCell	Substantia_nigra-Neuronal-Excitatory-eN1(Slc17a7)-eN1_1-Excitatory_Neuron.Slc17a7.C1ql3_(Hippocampus_Excitatory_Neuron)-\|Substantia_nigra / BrainAtlas - Mouse McCarroll V32	RGSL1 ZNF831 PRDM8 WNT10A	1.05e-04	97	112	4	1da964954a95c497ac4a24df1ea3575df5747025
ToppCell	Substantia_nigra-Neuronal-Excitatory-eN1(Slc17a7)\|Substantia_nigra / BrainAtlas - Mouse McCarroll V32	RGSL1 ZNF831 PRDM8 WNT10A	1.05e-04	97	112	4	dd188763ba02337e4f25d56766eda886cffa810d
ToppCell	Substantia_nigra-Neuronal-Excitatory-eN1(Slc17a7)-eN1_1\|Substantia_nigra / BrainAtlas - Mouse McCarroll V32	RGSL1 ZNF831 PRDM8 WNT10A	1.05e-04	97	112	4	a0242258aad0766450ff52fe28278cbb2b8d63a0
Computational	Genes in the cancer module 58.	CFH CFI C4BPA	2.05e-04	21	60	3	MODULE_58
Computational	Complement.	CFH CFI C4BPA	2.70e-04	23	60	3	MODULE_130
Disease	Drusen, Radial, Autosomal Dominant	CFH CFI	3.83e-05	3	106	2	C1852021
Disease	Malattia Leventinese	CFH CFI	3.83e-05	3	106	2	C1852020
Disease	phosphatidylinositol transfer protein beta isoform measurement	CFH MED16	3.83e-05	3	106	2	EFO_0802863
Disease	thrombospondin type-1 domain-containing protein 7A measurement	CFH C4BPA	3.83e-05	3	106	2	EFO_0803150
Disease	small conductance calcium-activated potassium channel protein 1 measurement	CFH MED16	3.83e-05	3	106	2	EFO_0803081
Disease	DOYNE HONEYCOMB RETINAL DYSTROPHY	CFH CFI	3.83e-05	3	106	2	C1832174
Disease	lymphotoxin alpha2:beta1 measurement	CFH MED16	3.83e-05	3	106	2	EFO_0020543
Disease	sperm-associated antigen 11A measurement	CFH MED16	3.83e-05	3	106	2	EFO_0802082
Disease	glucose-6-phosphate isomerase measurement	CFH CD163L1	3.83e-05	3	106	2	EFO_0020407
Disease	protein CYR61 measurement	CFH RUNX3	3.83e-05	3	106	2	EFO_0802929
Disease	t-cell surface glycoprotein CD8 beta chain measurement	CFH MED16	7.63e-05	4	106	2	EFO_0803135
Disease	alanine aminotransferase 1 measurement	CFH MED16	7.63e-05	4	106	2	EFO_0802260
Disease	integrin alpha-5 measurement	CFH MED16	7.63e-05	4	106	2	EFO_0802637
Disease	protocadherin beta-1 measurement	CFH MED16	7.63e-05	4	106	2	EFO_0802972
Disease	histone acetyltransferase type b catalytic subunit measurement	CFH MED16	7.63e-05	4	106	2	EFO_0020452
Disease	HELLP Syndrome	CFH CFI	7.63e-05	4	106	2	C0162739
Disease	ankylosing spondylitis, psoriasis, ulcerative colitis, Crohn's disease, sclerosing cholangitis	RNF186 IRF5 ZMIZ1 RUNX3 ZNF831 FAM118A TNFSF15	9.74e-05	295	106	7	EFO_0000384, EFO_0000676, EFO_0000729, EFO_0003898, EFO_0004268
Disease	C-type lectin domain family 4 member D measurement	CFH MED16	1.27e-04	5	106	2	EFO_0802347
Disease	potassium voltage-gated channel subfamily F member 1 measurement	CFH TF	1.27e-04	5	106	2	EFO_0802890
Disease	E3 ubiquitin-protein ligase NEURL1 measurement	CFH MED16	1.27e-04	5	106	2	EFO_0801554
Disease	adenylyltransferase and sulfurtransferase MOCS3 measurement	CFH MED16	1.27e-04	5	106	2	EFO_0802257
Disease	augurin measurement	CFH MED16	1.27e-04	5	106	2	EFO_0801399
Disease	scavenger receptor class A member 3 measurement	CFH MED16	1.27e-04	5	106	2	EFO_0803044
Disease	uncharacterized protein C3orf18 measurement	CFH MED16	1.27e-04	5	106	2	EFO_0802193
Disease	layilin measurement	CFH MED16	1.27e-04	5	106	2	EFO_0020529
Disease	mucin-1 measurement	CFH MED16	1.27e-04	5	106	2	EFO_0021841
Disease	fibroblast growth factor 5 measurement	CFH PRDM8	1.27e-04	5	106	2	EFO_0010784
Disease	pulse pressure measurement	CFH KDM5A IRF5 RREB1 ZNF831 SVEP1 DENND4C LDB2 MELTF PRDM8 PKD1 FAM118A GARRE1 DMAC1 TRMT12	1.35e-04	1392	106	15	EFO_0005763
Disease	fractalkine measurement	CFH MED16	1.90e-04	6	106	2	EFO_0020395
Disease	v-set and transmembrane domain-containing protein 4 measurement	CFH MED16	1.90e-04	6	106	2	EFO_0803247
Disease	zinc finger protein 276 measurement	CFH MED16	1.90e-04	6	106	2	EFO_0802227
Disease	peptidyl-prolyl cis-trans isomerase-like 2 measurement	CFH MED16	1.90e-04	6	106	2	EFO_0801877
Disease	aurora kinase B measurement	CFH MED16	1.90e-04	6	106	2	EFO_0020169
Disease	regulator of G-protein signaling 8 measurement	CFH MED16	2.65e-04	7	106	2	EFO_0801997
Disease	baculoviral IAP repeat-containing protein 5 measurement	CFH MED16	2.65e-04	7	106	2	EFO_0020174
Disease	C-C motif chemokine 1 measurement	CFH MED16	2.65e-04	7	106	2	EFO_0008041
Disease	uroplakin-3b-like protein measurement	CFH MED16	2.65e-04	7	106	2	EFO_0802204
Disease	glutathione S-transferase A4 measurement	CFH MED16	2.65e-04	7	106	2	EFO_0801637
Disease	sialic acid-binding Ig-like lectin 6 measurement	CFH SIGLEC8	3.53e-04	8	106	2	EFO_0008285
Disease	tumor necrosis factor receptor superfamily member 3 measurement	CFH MED16	3.53e-04	8	106	2	EFO_0020813
Disease	desmoglein-1 measurement	CFH MED16	3.53e-04	8	106	2	EFO_0020321
Disease	protein sel-1 homolog 2 measurement	CFH MED16	3.53e-04	8	106	2	EFO_0801962
Disease	alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 measurement	CFH MED16	3.53e-04	8	106	2	EFO_0801373
Disease	cadherin-related family member 5 measurement	CFH MED16	3.53e-04	8	106	2	EFO_0801440
Disease	chromobox protein homolog 5 measurement	CFH MED16	3.53e-04	8	106	2	EFO_0020258
Disease	calcium/calmodulin-dependent protein kinase type 1D measurement	CFH MED16	3.53e-04	8	106	2	EFO_0008063
Disease	kallikrein-6 measurement	CFH MED16	3.53e-04	8	106	2	EFO_0801739
Disease	PH and SEC7 domain-containing protein 1 measurement	CFH MED16	3.53e-04	8	106	2	EFO_0803302
Disease	atypical hemolytic-uremic syndrome (is_implicated_in)	CFH CFI	3.53e-04	8	106	2	DOID:0080301 (is_implicated_in)
Disease	epididymal-specific lipocalin-10 measurement	CFH MED16	4.53e-04	9	106	2	EFO_0801576
Disease	ectonucleoside triphosphate diphosphohydrolase 1 measurement	CFH MED16	4.53e-04	9	106	2	EFO_0020342
Disease	cyclin-dependent kinase 5:cyclin-dependent kinase 5 activator 1 complex measurement	CFH MED16	4.53e-04	9	106	2	EFO_0020296
Disease	C3 glomerulopathy	CFH CFI	4.53e-04	9	106	2	C4087273
Disease	Atypical hemolytic-uremic syndrome	CFH CFI	4.53e-04	9	106	2	cv:C2931788
Disease	cellular retinoic acid-binding protein 1 measurement	CFH MED16	4.53e-04	9	106	2	EFO_0801463
Disease	endothelin-converting enzyme 1 measurement	CFH MED16	4.53e-04	9	106	2	EFO_0008121
Disease	Hemolytic-uremic syndrome	CFH CFI	4.53e-04	9	106	2	cv:C0019061
Disease	synaptotagmin-11 measurement	CFH RREB1	4.53e-04	9	106	2	EFO_0802108
Disease	mast cell-expressed membrane protein 1 measurement	CFH MED16	4.53e-04	9	106	2	EFO_0801787
Disease	interleukin-34 measurement	CFH MED16	4.53e-04	9	106	2	EFO_0020505
Disease	heterogeneous nuclear ribonucleoprotein q measurement	CFH MED16	4.53e-04	9	106	2	EFO_0020443
Disease	DNA repair protein rad51 homolog 1 measurement	CFH MED16	5.65e-04	10	106	2	EFO_0020330
Disease	tropomyosin beta chain measurement	CFH MED16	5.65e-04	10	106	2	EFO_0020787
Disease	Atypical Hemolytic Uremic Syndrome	CFH CFI	5.65e-04	10	106	2	C2931788
Disease	response to carboplatin, response to antineoplastic agent	AKNAD1 CSMD1	5.65e-04	10	106	2	GO_0097327, GO_0097328
Disease	axin-2 measurement	CFH MED16	5.65e-04	10	106	2	EFO_0801400
Disease	obstructive jaundice (biomarker_via_orthology)	CFH IRF5	5.65e-04	10	106	2	DOID:13603 (biomarker_via_orthology)
Disease	interleukin-37 measurement	CFH MED16	5.65e-04	10	106	2	EFO_0020506
Disease	insulin growth factor-like family member 3 measurement	CFH MED16	5.65e-04	10	106	2	EFO_0801700
Disease	stromal interaction molecule 1 measurement	CFH MED16	5.65e-04	10	106	2	EFO_0802093
Disease	PR domain zinc finger protein 1 measurement	CFH MED16	6.88e-04	11	106	2	EFO_0801904
Disease	interleukin-22 receptor subunit alpha-2 measurement	CFH RUNX3	6.88e-04	11	106	2	EFO_0020500
Disease	interleukin-10 receptor subunit alpha measurement	CFH MED16	6.88e-04	11	106	2	EFO_0021890
Disease	glycerol-3-phosphate dehydrogenase 1-like protein measurement	CFH MED16	6.88e-04	11	106	2	EFO_0801640
Disease	gout	RUNX2 RREB1 PRDM8 CNIH4 CNTNAP2	7.24e-04	196	106	5	EFO_0004274
Disease	oncostatin-M measurement	CFH MED16	8.24e-04	12	106	2	EFO_0010792
Disease	tyrosine-protein kinase ZAP-70 measurement	CFH MED16	8.24e-04	12	106	2	EFO_0020833
Disease	kallikrein-12 measurement	CFH MED16	9.72e-04	13	106	2	EFO_0008194
Disease	T-cell surface glycoprotein CD3 epsilon chain measurement	SELP CFH	9.72e-04	13	106	2	EFO_0802114
Disease	wet macular degeneration	CFH CFI	1.13e-03	14	106	2	EFO_0004683
Disease	Abnormality of chromosome segregation	ODAD2 RUNX3 FCER2	1.33e-03	60	106	3	HP_0002916
Disease	preeclampsia, hypertension, pregnancy-induced	ZNF831 PRDM8	1.48e-03	16	106	2	EFO_0000668, MONDO_0024664
Disease	preeclampsia, parental genotype effect measurement	ZNF831 PRDM8	1.48e-03	16	106	2	EFO_0000668, EFO_0005939
Disease	vital capacity	CFH JADE2 ODAD2 ZMIZ1 RUNX2 RREB1 SVEP1 MELTF ADAMTS6 FBXL2 PPP6R2 DMAC1	1.62e-03	1236	106	12	EFO_0004312
Disease	SLAM family member 7 measurement	CFH RUNX3	1.68e-03	17	106	2	EFO_0008287
Disease	Antibody Deficiency Syndrome	CFH EPG5	1.68e-03	17	106	2	C0003257
Disease	Age-related macular degeneration	CFH CFI	1.88e-03	18	106	2	cv:C0242383
Disease	diabetes mellitus	OR5V1 ZMIZ1 RREB1	1.91e-03	68	106	3	EFO_0000400
Disease	response to methotrexate, juvenile idiopathic arthritis	ZMIZ1 CSMD1	2.10e-03	19	106	2	EFO_0002609, GO_0031427
Disease	respiratory symptom measurement, COVID-19	RBM10 GRIN2B CSMD1	2.43e-03	74	106	3	EFO_0007939, MONDO_0100096
Disease	esophagus squamous cell carcinoma (is_marker_for)	RUNX2 RUNX3 TERT	2.43e-03	74	106	3	DOID:3748 (is_marker_for)
Disease	COVID-19 (is_implicated_in)	CFH C4BPA	2.57e-03	21	106	2	DOID:0080600 (is_implicated_in)
Disease	e-selectin measurement	NPDC1 DMAC1	2.82e-03	22	106	2	EFO_0004575
Disease	Immunologic Deficiency Syndromes	CFH EPG5	3.08e-03	23	106	2	C0021051
Disease	Sjogren's syndrome (is_marker_for)	SELP MUC19	3.35e-03	24	106	2	DOID:12894 (is_marker_for)

Protein segments in the cluster

Peptide	Gene	Start	Entry
PKARSSSARWALTCC	TNFSF15	26	O95150
NVCPNSWRSKTLKDC	nan	411	A8MVM7
SHWSAPAPQCKALCR	C4BPA	471	P04003
LSPECWKATLRALGC	EPG5	1846	Q9HCE0
WKATLRALGCCAPSC	EPG5	1851	Q9HCE0
NLSDGQKCRVCLAWL	ABCF2	516	Q9UG63
LSCDKVFCQPWQRCI	CFI	41	P05156
TSPAEHRLLKTCWSC	DMAC1	36	Q96GE9
KCVCNWASRLFAPNV	CDRT15L2	261	A8MXV6
LWDRSLPKCLAISCG	CSMD1	2846	Q96PZ7
AANCLWLLTNSKPCA	ANKIB1	506	Q9P2G1
ITCKDGRWQSIPLCV	CFH	851	P08603
QCPKTHISIWQCLSA	CD163L1	1211	Q9NR16
KFCQTIKCRANWRPA	PKD1L1-AS1	51	Q9H7B7
LSCNRDILCPSDWTV	ADAMTS12	936	P58397
WCLSKSNRCVTNSIP	ADAMTS6	511	Q9UKP5
KWNSVADCLPCVFLV	RAG2	171	P55895
WQKLACLLCRRQFPS	RBM10	756	P98175
CCCFLLWAPALTLKN	PCDH17	6	O14917
CDLCLKWRVLPSSTN	MORC1	486	Q86VD1
WACPACTLLNALRAK	CAPN15	416	O75808
PDCRFSWLCVLLLSS	MFRP	61	Q9BY79
FQWLCSDSLKLCCPA	CRELD1	131	Q96HD1
TLCRCAQISKAWNIL	FBXL2	31	Q9UKC9
NLDWSSACSCPLLIF	DGKK	481	Q5KSL6
RLASWIKSQDPSVCC	nan	26	O00370
LLTCCIAQKPSCRWS	FAM86C1P	86	Q9NVL1
SPRDCLKTCLFQKWQ	LDB2	226	O43679
SNTPIWACRLRSCEK	CARF	201	Q8N187
WLCRTCALGVQPKCL	JADE2	241	Q9NQC1
HIPASRWALSCSLCK	JADE2	301	Q9NQC1
CRSRSWIQKPDSVCS	KIF27	661	Q86VH2
CSAVGVCVSWRKPNL	MUC19	1521	Q7Z5P9
ADICNPCRTWELSKQ	PDE7A	361	Q13946
CNSPDCSAWKTVSRI	NEMP1	366	O14524
KLGAWVCDRLATCTP	FCER2	276	P06734
TQRCLSVLFPIWFKC	MRGPRD	121	Q8TDS7
LICTWLSCFAGRNPK	LHFPL1	181	Q86WI0
AIRLCQCKVFWSGPC	IRF5	336	Q13568
WLPRSHCTAQLCASL	OR2I1P	91	Q8NGU4
RKLWSRTFNCSVPCS	OSTM1	266	Q86WC4
PLICWKECRSRQSSA	GREB1L	231	Q9C091
SSWQAKEVKFLCPLC	KDM5A	1201	P29375
QDLVNRTPWKKCCFS	RBBP5	246	Q15291
PSVPLACAWSCRNLI	MED16	31	Q9Y2X0
AAALSVASLCWCRLQ	NPDC1	196	Q9NQX5
LSKVLCNQLAASCWA	OR5V1	136	Q9UGF6
IPALCSWRSCIEAVI	FAM118A	46	Q9NWS6
AWCLRCVAVALPFQL	HEATR5B	466	Q9P2D3
LQASSCEVPLHWVCK	KLRG1	171	Q96E93
WLQCDCRPFKQALLS	DNAH17	1061	Q9UFH2
TPKCARCRNHGVLSW	DMRT3	26	Q9NQL9
KKWPCLASLSTLDLC	FBXO15	231	Q8NCQ5
LIWNRAQSCPTFLCA	ATPAF1	186	Q5TC12
LNQVCPSTWRGACKT	GARRE1	396	O15063
VLKCDWSSTRRCQPI	ITGAV	86	P06756
ALCALVATIWFPVCA	CLDN11	131	O75508
LRKFPALVNCCTIDW	DNAH7	2486	Q8WXX0
SINTNKCICLLSHWP	DENND4C	306	Q5VZ89
SPSCAFCRRLLEWKQ	AKNAD1	601	Q5T1N1
QWTAVTPACRAVKCS	SELP	691	P16109
CLCRAWTAPSTSQKC	CNTNAP2	21	Q9UHC6
WLDPQTLLTCCLVSK	FBXW2	71	Q9UKT8
LGCSLWPVICLNKRT	CHIC1	156	Q5VXU3
LLTCCIAQKPSCRWS	FAM86C2P	86	A6NEL3
LLDVWSTCSQPICAK	DSEL	816	Q8IZU8
PALNLLWEKCCSDNV	FOCAD	46	Q5VW36
TCLSLWTARIFPVCS	FPGT	531	O14772
AWNVCVTRKAPLLAS	PPP6R2	806	O75170
TWACPACALRLLAAT	PKD1	761	P98161
KVCLQAALRAWNSCN	PIWIL1	676	Q96J94
NTWSITCPLCRKVTA	RNF186	76	Q9NXI6
FLCSVLPSHWRCNKT	RUNX2	121	Q13950
CSVLPSHWRCNKTLP	RUNX3	76	Q13761
TWLEKCRLPFFCKTN	RGSL1	66	A5PLK6
CVACHRSQLSKPWGI	TRIM32	461	Q13049
PSFWCRSQEAAKLCN	PSAPL1	486	Q6NUJ1
LRWCVLSTPEIQKCG	MELTF	366	P08582
CWVRSDNKRPCLEFS	LIPI	11	Q6XZB0
ASAAWALCPCIKNAK	ODAD2	856	Q5T2S8
LAQRLRWLCDSCPAS	NBEAL2	471	Q6ZNJ1
FTSLCLPAQNWCAKC	PRDM8	616	Q9NQV8
AACKSLPCARWNLAH	PTCH2	656	Q9Y6C5
QPAQLTTVGKRCCLW	ADSL	161	P30566
RTCCLLSAPNLNSWK	SEMA4A	521	Q9H3S1
RNLTCSVPWACKQGT	SIGLEC8	171	Q9NYZ4
IPSSRWALVCSLCNE	JADE1	306	Q6IE81
LCLENRKWSGASPRC	SVEP1	2756	Q4LDE5
NARSCCSKLNKWVIP	CNIH4	36	Q9P003
PSSVHCGCSKQWRLR	RPP38-DT	56	Q8N326
CGCSKQWRLRLPSES	RPP38-DT	61	Q8N326
NPFTCWLVCTCVKQR	NLRP9	336	Q7RTR0
LWFNREKTCPLCRTV	RNFT1	401	Q5M7Z0
LCLAVPDKTVRWCAV	TF	16	P02787
ILKCWAHSEVAAPCA	PIGX	181	Q8TBF5
CRKFPRISQAWCETN	RREB1	291	Q92766
QRLKLWVCCLCLGPA	PTGIR	301	P43119
SDQTCAISWPLLQKC	WDHD1	166	O75717
LSRPLECACFRTSIW	RRAGA	151	Q7L523
NLEFDICSIWCSKPI	TTC3	61	P53804
LCCVAFSLLWASPVN	TRBV6-1	6	A0A0K0K1D8
TWRCPVCNKTALLEG	ZMIZ2	636	Q8NF64
VCRSNKSPWVCLTCS	USP3	31	Q9Y6I4
SCFICLLASQWAISP	PIGO	461	Q8TEQ8
CSPAQKLCLEVSRWV	TRMT12	101	Q53H54
TPSLACANKCVFCWR	TYW1	411	Q9NV66
CQLKTCWQVTPEFRT	WNT10A	271	Q9GZT5
SLKAEPRLTWCCLSR	ZNF831	1176	Q5JPB2
RDLKSCNRPCVWSRL	ZNF22-AS1	31	Q5T742
QCSICLKAFARPWSL	ZNF579	271	Q8NAF0
AFRALVAQCLVCVPW	TERT	46	O14746
RGTWRCPVCNKTALL	ZMIZ1	776	Q9ULJ6
IAVCKLQACARWAVT	TTF2	751	Q9UNY4
TCTCLAWAPARLQAK	WDR43	61	Q15061
ALSCLRCGKQFTVAW	ZNF296	156	Q8WUU4
CEAALRAPVWAQCAS	ZAN	2141	Q9Y493
RLELWFCQLAAPACK	NLRP13	871	Q86W25
ECCSPKFWLVLAVLA	GRIN2B	6	Q13224